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PUBLISH OR PERISH Writing and Publishing Scientific Manuscripts

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PUBLISH OR PERISH Writing and Publishing Scientific Manuscripts

www.jiasociety.orgJournal of the International AIDS Society

Workshop Outline

1. Journal of the International AIDS Society (JIAS)

2. How to write a scientific manuscript

3. Pre-submission do’s and don’ts4. What happens after submission5. Editors’ panel discussion

www.jiasociety.orgJournal of the International AIDS Society

www.jiasociety.orgJournal of the International AIDS Society

• Quality

• Originality

• Good methods

• A good fit to the journal

• No trouble

What editors want ☺

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Writing & Science

From a scientific point of view –

Results that are not published means the research did not take place

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It’s all about the question…

QuestionQuestionAnalysis of the data

Design and implementation

of research

Discussion of the findings

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Manuscript structure

Title/title pageAbstract

IntroductionMethods and materials

ResultsDiscussionReferences

Tables and Figures

What is the most important part of a scientific article?...

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Title

Title

Abstract

Main

text

The part most often readOften the only part read

ShortSpecific

RepresentativeInformative

Effect of multiple micronutrient supplementation on survival of HIV-infected children in Uganda: a randomised controlled trial

Ndeezi et al, JIAS 2010

cohort

setting design

intervention outcome

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Abstract

• Main problems encountered by editors:– Inconsistent – Incomplete

• Brief summary • Complete

– Background– Experimental design– Major findings– Conclusion

• Stand alone• Consistent with the paper

Title

Abstract

Maintext

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Introduction: What was your question?

• Background – context for understanding the question

• Problem – nature and importance of problem

• Question – underlying research

• Forecasting – mini-summary for readers

Problem: authors write as if readers know as much as they do

Funnel-shaped, from general to specific

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Methods/Materials: How did you examine your hypothesis?

• Validates your study• Use subheadings to organize this

section if needed• Details on ethical approval and patient

consent• Detailed enough to allow replication

– Procedures, materials used, data collected, data analysis and statistical methods

• Past tense• No results yet!

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Results: What did you find?

• What is the best way to present your data: table, figure or text?– Avoid repetition

• Present only the results relevant to your hypothesis

• Relate results to methods, but do not describe them again

• Do not discuss yet!

!!! Careful with the word ‘significant’

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Figures: Different figures for different messages

Change over time

Source: UNAIDS/WHO, 2008

0

5

10

15

20

25

1990 1993 1996 1999 2002 2005

Adult HIVprevalence (%)High estimate

Low estimate

• Only when helpful to convey information• Should be understandable without text• Choose type based on the kind of data you have

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Figures: Different figures for different messages

• A bar graph would work for a different type of data:

Source: UNAIDS/WHO, 2006

Ratios

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Discussion: What do your findings mean?

• Do not repeat results, but should be based on the results!

• Discuss the importance and implications of your findings

• Describe any limitations of the study• Conclude with the key points• Did the results answer your

question?

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Criteria for evaluating qualitative analyses

• Significance of the data set; contextualization and production conditions

• Sufficiency of the data• Coverage of the analysis• Transparency and repeatability of the

analysis

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Which section of a manuscript usually contains the most errors?

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References

• Credibility– Knowledge and awareness of the field– Validates your claims and arguments

• How to write references:– Pay attention to the ‘Instructions for Authors’of your selected journal

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Cover letter

• Editors read the cover letter ☺

• Statements of manuscript submitted to one journal only and not previously published.

• Your chance…– to highlight the importance of your study– to explain why manuscript of interest to

journal

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deadly sins

• Carelessness• Redundancy• Unfair authorship• Undeclared conflicts• Subject violations• Plagiarism• Fraud

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To do and not to do in manuscript submission

Elise Langdon-Neuner

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Choosing a Journal

Traditional list

• Journal’s prestige (Impact factor)

• Publication speed

• Circulation

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Choosing a journal

• Coverage by abstracting + indexing

• Open access

• Influence

• Cost

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High impact factor pros

• Citation rates more strongly influenced by journal IF than by merits of the study(JAMA 2002)

• Reviews might help improve paper for resubmission

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High impact factor cons

• Acceptance rates of high impact journals often below 10%

• Delay if rejected

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How easy is it to get published?

0102030405060708090

100

Acc

epta

nce

rate

BMJ JAMA JIAS J InfectDis

AIDS PlosOne

Journal(from 2009)

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Practical approach

• Look at article• Subject matter—of national/international interest• Who will be interested• Reference list

• Look at journals• Types of topic• Author instructions for scope• Editorial board• New journal-will it survive?

• Ask colleagues

Have a second choice ready

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A website that might help

• http://www.biosemanitcs.org/jane

• This website searches for journals in the field

• You insert your abstract in the box provided

• The site compares your abstract with articles on Medline and produces a list of possible journals for your article

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Where are the instructions?

• Instructions to authors: journal webpage

• Examine a recent issue of the journal

• Uniform Requirements for Manuscripts submitted to Biomedical Journals (ICMJE) [www.icmje.org]

• CONSORT (Consolidated Standards of Reporting Trials) [www.consort- statement.org] NB NEW STATEMENT

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Most often ignored instructions

• Word counts

• Reference formats: in-text citations or referencing incorrect

• Tables/figures: inserting in the text rather than at the end of the manuscript or as separate files

• Poor quality: figures/photos or non-standard formats

• Abbreviations: failure to write out the first time they are written in the manuscript

• Photos of patient: lack of consent/confidentiality of body parts

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Look out for limitations

in number of • Authors

• Words

• References

• Tables/Figures

• Characters in running title

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Format

Check• Format required for manuscript:

Word, pdf, figures included in file/separate

• Structured abstract?• Format for references• Format for figures• Cover letter required

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Forms

• The contributions made by each author

• The conflicts of interest of each author

• Also to be included in the manuscript?

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Electronic submission

Information needed:

• Authors’ full names, email, MD/PhDs

• Corresponding author’s keywords

• Preferred/non-preferred reviewers + email, addresses

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Manuscripts sent back because...

• Authorship/COI form not signed by every author

• No title page, no abstract

• No figure legends

• Incorrect figure/table labels

• Reference order incorrect, usage of et al. in references

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Failure to revise and resubmit

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Reviewer’s comments

• Comply with as many reviewer requests as possible

• Disagree or explain reasons for non- compliance politely and well argued

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Categorising comments

• Difference of opinion irresolvable

• Request impossible

• Request possible but impracticable

• Difference of interpretation

• Request acceptable

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Replying to reviewers’ comments

• Point-by-point reply

• Highlight the changes you have made clearly

• Keep your reply short and to the point

• Answer reviewers’ questions in the manuscript

—not only in your reply to reviewer’s comments

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Prior publication

• Key is whether prior publication was work in progress or completed work

• Congress abstracts, posters, proceedings = work in progress

• Eprints?

• Posting trial results on a clinical trial registry?

NB: FDA Amendment Act

• http://chestjournal.chestpubs.org/cgi/collection/mwt

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Editorial black box

Online submission

Initial decision by Editors

Reviewed by at least 2 selected experts

Accept

Revision

Reject

Published in JIAS - open access

Revision reviewed

Reject

Mentoring

Mentoring

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that you always wanted to ask an editor

YOUR questions

What editors want?

What are the reasons for instant rejection?

What are the reasons for rejection after revision?

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Editor’s checklist upon submision

• Objective • Scientific importance • Originality and novelty• Validity• Presentation quality

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Common reasons for instant rejection

Journals have a duty to avoid wasting referee time and undue delays in responding to authors

x Not within Journal’s scope

x Manuscript type unacceptable

x Ignores instructions to authors

x Major methodological weakness

x Clear ethical problems

x No clear hypotheses / objective

x Incorrect analysis & conclusion

x Lack of Statistical analysis

x Nothing new

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Editors’ decisions depend on:

o Importance, originality

o Reviewers’ concerns

o Fatal flaws

o Journal Philosophy

o Space available

o The quality of the competition

o Editorial work required

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The Balance between Innovation and Rigour

The perfect paper has important new ideas backed up by sound data from thoroughly validated methods.

In real papers there is a trade-off between innovation and quality of data.

Good luck!

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How did we do?

• Please take a minute to fill out our evaluation form.

• Many thanks for your participation.

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http://www.emwa.org/, click journal, then free sample copy of TWS

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Editors' concerns I need to be aware of

• Ghostwriters

• Conflicts of interest

• Prior/duplicate/salami publication