pten proteins - molecular basis
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MOLECULAR BIOLOGY
SIMÓN RESTREPO ARISMENDYMedicine Student
UPB
Scientists Identify Molecular Basis for DNA Breakage, a Hallmark of Cancer Cells
Targeting PTEN May Prevent Skin Cancer
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INTRODUCTION
Sounds like an easy thing, but it´s a very complex molecular process
Even a tiny mistake in the DNA replication can cause terrible diseas like
cancer
TARGETING PTEN MAY PREVENT CANCERScienceDaily (july26, 2011)
TARGETING PTEN MAY PREVENT CANCER
Non-melanome skin cancer is the most common cancer in the United States.
PTEN proteins promote cellular repair
TARGETING PTEN MAY PREVENT CANCER
Cells with low PTEN protein were more likely to hace UVB-induced skin cancers.
Reduced levels of PTEN proteins could lead to cancer and tumor progression.
TARGETING PTEN MAY PREVENT CANCER
Increasing PTEN protein activity could reduce skin
cancer and tumor progression.
OBSERVATION
This study, has made a breakthrough the
understanding the PTEN protein function and the way to prevent skin cancer and
tumor progression, which is a huge and a really important
step in the war against oncology diseases.
SCIENTIST IDENTIFY MOLECULAR BASIS FOR
DNA BREAKAGE, A HALLMARK OF CANCER
CELLSSCIENCEDAILY (JULY 19, 2011)
Scientist identify Molecular Basis for DNA Breakage, A Hallmark Of Cancer
Cells
The DNA encodes the entire genetic information required for building the proteins of
the cell.
Under stress condition, DNA usually breaks.
Scientist identify Molecular Basis for DNA Breakage, A Hallmark Of Cancer Cells
DNA breaks leads in an uncontrolled cell division and
at the end in a cancer development
The study shed a light on the regulation of DNA replication
along the fragile sites
Scientist Identify Molecular Basis for DNA Breakage, A Hallmark Of Cancer
Cells
Fragile sites, where the DNA breakage begins, is a site that slow and also can stop DNA
replication.
OPINION
This study, has made a breakthrough the
understanding the PTEN protein function and the way to prevent skin cancer and tumor progression, which is a huge and a really important step in
the war against oncology diseases.
Medical Utility
Medical Utility
.
Both studies could let the scientist have more tool to keep investingation around more genetic troubles that
could end in cancer
Medical Utility
Founding cancer genetic causes and all the
molecular process that increase posibilty of
developing this diseas, could end in some
nutrition regim that gives the posibilty to prevent some specific cancer.
Medical utility
Scientist could develop better treatments or even a cure for
cancer.
BIBLIOGRAPHY
1. Targetin PTEN may prevent skin Cancer. American Association for Cancer Research . 2011, July 26. ScienceDaily [online]. Retrieved August 6, 2011, from http://www.sciencedaily.com/releases/2011/07/110726132351.htm
2. Scientists identify molecular basis for DNA breakage, a hallmark of cancer cells.. Hebrew University of Jerusalem. 2011, July 19. ScienceDaily [online]. Retrieved August 6, 2011, from http://www.sciencedaily.com/releases/2011/07/110719094023.htm
3. Martinez S Lina María. Biologia Molecular. 6 ed.
Medellin. UPB. Fac Medicina. 2011, 74-75p
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