prrsv control and eradication in spanish farms enric marco marco i collell; s.l
TRANSCRIPT
PRRSV control and eradication in Spanish farmsEnric Marco
marco i collell; S.L.
PRRS is possible
• “Test and removal” (Dee and Molitor, 1998),• Closed up of the herd (Torremorell and
Christianson, 2001) • Partial depopulation (Plomgaard, 2001)
Critical points
• Persistence of the virus (Zimmerman, et al., 1992) • 152 days in tonsils of infected animals (Wills, et al.
1997) • 92 days in semen (Christopher-Hennings et al., 1995,
Swenson et al. 1994)• Viremic piglets can shed virus up to 7-16 weeks
(Benfield et al., 1996)
Case 1: PRRS eradication in a small farrow to finish herd
The farm
• Year 2,000• 230 sows farm• Farrow to finish herd.• Batch farrowing every 15 days.• Finishing capacity: 50%• Sows: LD x LW• Boars: Pietrain-Halothane (-) (I.A.)
Sus Scrofa (Cal Rech, Barcelona)
The farm
The farm
The farm –health status
• Aujeszky’s disease• PRRS• Mange• Mycoplasma hyopneumoniae• Actinobacillus pleuropneumoniae• Finishing mortality up to 25-30%
Objective
• Eradicate:• PRRS• App• Mange
Eradication plan
• Switzerland eradicate M. hyo from small herds (Zimmerman, 1996).
• Denmark, the same methods are apply in larger herds (Plomgaard, J. 1998)
BASES:• No animals present younger than 10 month of
age.• No replacement during 6 months.• Nursery and finishing depopulation.• Stop farrowing or move them to other facilities.
• Medicate the remaining stock
Eradication plan
• Medication all remaining animals:• 5 injections of enrofloxacin (2,5 mg/Kg. BW) on days
1, 4, 8, 11 and 14.• 2 injections of Doramectin (3 mg./Kg. BW) 14 days
apart.
• Good cleaning and disinfection of empty rooms.
Eradication plan
• Sows wean outside farm were located in isolation during 15 days• Where received Enrofloxacin and Doramectin.• A.I. during this period.
• Remodelling took place during the eradication time.
Eradication plan
Results
• No clinical signs of mange observe till now. • No mange control is done.• No lesions, no clinical signs of App
observed till now.
Results
• M.hyo is still present on the farm.• Replacement come from a positive
source.• Farm produced PRRS negative stock
until December 2001 when became reinfected.
Case 2: PRRS eradication in a small farrow to finish Boar multiplier by total depopulation
The farm
• Year : 2,002• 300 sows farm• Farrow to finish herd.• Boar multiplier• Batch farrowing every week.• Finishing capacity: 50% (boars and replacement) • Sows: LW and (LW x Pt)• IA in the farm: 5 boars: Pietrain
The farm
The farm
The farm –health status
• Mycoplasma hyopneumoniae• PRRS infected in August 2001
BASES:
• Stop positive replacement during 6 months.• Nursery and finishing depopulation.
Eradication plan
Farm lay out
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
Eradication starts. January 2002
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
Last PRRS negative replacement moved in
Eradication: March 2002
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
Last Replacement PRRS (+)
At 3 weeks piglets are weaned outside
Replacement of all AI boars by PRRS (-)
Eradication: September 2002
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
Piglets are weaned again inside
Eradication: October 2002
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
NEW PRRS negative replacement moved in
Eradication: December 2002
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
All samples Show PRRS negative
results
Eradication: January 2003
500 m.
GestationFarrowing roomNurseriesFinishing barnsPoultry barns
PRRS (+)
Eradication continues
• January 2004: same process is done again• October 2004: Positive animals in Finishing
again• EXTERNAL FINISHING HAS NOT BEEN
EMPTIED
Eradication continues
• January 2005: TOTAL DEPOPULATION• May last PRRS (+) sows farrow• July 2005 first sows farrow• To accelerate the program matings has been done out side.• New stock: • PRRS negative• M. hyo negative
Case 3: PRRS eradication in a 3 sites herd
The farm
• Year 2,003• 1.400 sows multiplier farm• 3 sites herd.• Farrowing every week.• Sows: Lw and Ld x Lw• AI boar stud in farm • 6 Boars: LD and (Lw x D)
The farm
The farm –health status
• Mycoplasma hyopneumoniae• PRRS
Farm lay out
> 10 Km.
GestationFarrowing roomNurseriesFinishing barns: Own replacement
SITE 1
SITE 2
EXTERNALSITE 3
> 1000 Km.
Future farm lay out
> 10 Km.
GestationFarrowing roomNurseriesFinishing barns: Own replacementand gilts to sale
SITE 1
SITE 2
SITE 3
3 Km.
800 m.
BASES:
• Stop positive replacement during 6 months.• Nursery and finishing depopulation. Using the
possibility of new facilities.
Eradication plan
Eradication Plan
• March 2003: Last replacement PRRS (-)• June 2003: Last replacement show titers to PRRS• June 2003: Inside nurseries emptied• July 2003: 4 weeks after, weaned pigs moved to
new sites 3 (wean to finish)• Own replacement and few more to fill up barns.
Eradication Plan
• July 2003: inside nurseries emptied• October 2003: Inside Finishing barn emptied• November 2003: New PRRS replacement located
in new inside finishing barn.• Managed independently.
• November 2003 old inside finishing remodeled to gestation
• December 2003: • Elimination of any gilt or sow PRRS (+) not mated.• Stop using PRRS (+) boars
Eradication Plan
• February 2004: Replacement in new site 3 negative to PRRS is moved to site I.
• March 2004: last farrowings from PRRS (+) sows• April 2004: first farrowing from new PRRS (-) gilts.• April 2004: weaners moved to new Site 2.• April 2004: Old site 2 is emptied.
Results
• Up today all analysis have shown negative results form all sites.
Production gaps
• Form last replacement negative to become positive: 3 m.
• From last replacement negative to first weaners (future replacement on external site) that remain on farm: 4 m .
• From last replacement once positive to new replacement negative: 5 m.
Case 4: PRRS eradication in a 3 sites herd without partial depopulation
The farm
• Year: 2,006• 800 commercial farm• 3 sites herd.• Farrowing every second week.• Sows: Ld x Lw• AI boar stud in farm • 4 Boars: Pietrain
• Own replacement• GP’s external source
The farm
Site 1
Site 2
The farm: site 1
Gestation
Farrowing
Own replacement
The farm: site 2
History
• 400 sows close herd• 1992 PRRS infection• 1998 control PRRS• Own-replacement• Gp’s + F1 acclimatization (contact with viremic pigs)
• 2002 • Change to 3 sites system• Increase population from 400 sows to 750
• 2006• PRRS circulating on site 2 + 3• No circulation on sow herd
The farm –health status
• Mycoplasma hyopneumoniae• PRRS
BASES:
• Stop positive replacement during 1 month.• No nursery depopulation
Eradication plan
Eradication Plan
1. Stop recirculation on site 2 (8-9 weeks of age)• Increase Biosecurity among batches• Different boots per barn• Specific material per barn (syringes, medicines, etc)
2. Once recirculation on site 2 stops (week 0)• Stop introduction of F1 on site 1 (once first batch is
detected negative) one month (two consecutives batches).
• Move negative F1 from site 2 to isolated external finishing and keep them isolated. (week 2)
The farm: site 2
Eradication Plan
3. Control PRRS status on site 2 (week 12)4. Control PRRS status last replacement PRRS positive
still on farm by PCR (week 16).• If PCR negative• Move negative F1 to site 1 (week 20)• Breed negative F1 (week 26)• Keep them isolated from the rest of the sows util gestation is
confirmed (4 weeks)
5. Week 30: Herd come back to normality
Results
• Farm has been PRRS negative up to January 2012
Production gaps
• From last replacement positive to new replacement negative: 1 m.
• But new replacement kept in isolation during 6 months.
Conclusions
• PRRS elimination is possible, but not always easy.
• People on farm have to be involved on the project.
• Replacement and weaners are critical areas for PRRS control.
• Good location and biosecurity are essential to maintain PRRS free status.
Thank you for your attention