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Proteins Chapter 5 Big Idea #2: Structure Meets Function

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Proteins. Chapter 5 Big Idea #2: Structure Meets Function. Basic Unit of Proteins. Amino Acid: Review: What are the constant domains of an amino acid? What is the variable region?. Types of Amino Acids. What functional groups can you recognize in the variable regions? - PowerPoint PPT Presentation

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Page 1: Proteins

ProteinsChapter 5

Big Idea #2: Structure Meets Function

Page 2: Proteins

Basic Unit of Proteins

Amino Acid:

Review:

What are the constant domains of an amino acid?

What is the variable region?

Page 3: Proteins

Types of Amino Acids What

functional groups can you recognize in the variable regions?

How might these impact how the variable region functions?

Page 4: Proteins

How does the amino acid chain dictate protein

structure?

Page 5: Proteins

Modeling Activity

Let’s use pipecleaners to model protein structure.

What limitations do we have?

Page 6: Proteins

What impacts each level of structure?

Page 7: Proteins

Key Protein Functions

Can you give an example of each? (In case a multiple choice gives examples instead of categories?!)

Enzymes

Hormone

Receptor

Contractile

Defensive

Transport

Storage

Structural

Page 8: Proteins

Structure Meets Function

Case Study: Hemoglobin

What differs?

How might this cause such a

significant change in protein

structure?

Page 9: Proteins

Sickle Cell Disease

Page 10: Proteins

Structure Meets Function

Case Study: CJD and Prions

Prions: Misfolded proteins

Can be infectious agents!

Page 11: Proteins

Protein Project!!! Goal:

To connect Big Ideas #1 & 3 (Evolution and continuity of proteins) to Big idea #2 (How proteins work)

Work in Pairs By Function

Your job is to find TWO examples for each function and present a poster session to connect the two examples.

Research structure meets function using primary sources and figures from primary sources.

Research evolution using a BLAST to find and compare similar protein sequences in various organisms.