proteins
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Proteins. Chapter 5 Big Idea #2: Structure Meets Function. Basic Unit of Proteins. Amino Acid: Review: What are the constant domains of an amino acid? What is the variable region?. Types of Amino Acids. What functional groups can you recognize in the variable regions? - PowerPoint PPT PresentationTRANSCRIPT
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ProteinsChapter 5
Big Idea #2: Structure Meets Function
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Basic Unit of Proteins
Amino Acid:
Review:
What are the constant domains of an amino acid?
What is the variable region?
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Types of Amino Acids What
functional groups can you recognize in the variable regions?
How might these impact how the variable region functions?
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How does the amino acid chain dictate protein
structure?
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Modeling Activity
Let’s use pipecleaners to model protein structure.
What limitations do we have?
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What impacts each level of structure?
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Key Protein Functions
Can you give an example of each? (In case a multiple choice gives examples instead of categories?!)
Enzymes
Hormone
Receptor
Contractile
Defensive
Transport
Storage
Structural
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Structure Meets Function
Case Study: Hemoglobin
What differs?
How might this cause such a
significant change in protein
structure?
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Sickle Cell Disease
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Structure Meets Function
Case Study: CJD and Prions
Prions: Misfolded proteins
Can be infectious agents!
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Protein Project!!! Goal:
To connect Big Ideas #1 & 3 (Evolution and continuity of proteins) to Big idea #2 (How proteins work)
Work in Pairs By Function
Your job is to find TWO examples for each function and present a poster session to connect the two examples.
Research structure meets function using primary sources and figures from primary sources.
Research evolution using a BLAST to find and compare similar protein sequences in various organisms.