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Prof. Peter Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics | www.hzdr.de Timing RPC for prompt gamma radiation detection RPC 2016 Lothar Naumann

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Page 1: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Prof. Peter Mustermann | Institut xxxxx | www.hzdr.deSeite 1

Dr. Lothar Naumann | Institute of Radiation Physics | www.hzdr.de

Timing RPC for prompt gamma radiation detection

RPC 2016Lothar Naumann

Page 2: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 2

E = 70 - 230 MeVI = 3 - 200 nA

• Proton therapy is a modern treatment for deep seated tumors

• Tumor dislocation or modification during the treatment period occurs

• Improvement of the proton therapy with online beam parameter settings

RPC for Proton Therapy

Page 3: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 3

E = 70 - 230 MeVI = 3 - 200 nA

• Proton therapy is a modern treatment for deep seated tumors

• Tumor dislocation or modification during the treatment period occurs

• Improvement of the proton therapy with online beam parameter settings

PRC for Proton Therapy

Page 4: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 4

E = 70 - 230 MeVI = 3 - 200 nA

• Proton therapy is a modern treatment for deep seated tumors

• Tumor dislocation or modification during the treatment period occurs

• Improvement of the proton therapy with real time range assessment

RPC for Proton Therapy

Page 5: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 5

gantryPET

annihilation gamma

prompt gammaPrompt Gamma Spectrum

Treatment control

Page 6: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 6

prompt gammaPrompt Gamma Spectrum

Treatment control

• Prompt Gamma Timing: Timing Detector timing resolution and count rate capabilities →RPC ?

• Prompt Gamma Imaging: Slit camera spatial resolution and count rate capabilities →RPC ?

• Prompt Gamma Origin: Compton camera spatial, time and energy resolutions and count rate capabilities → no RPC !

Page 7: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 7

Ceramics RPC efficiency (sim.)

Compton scattering in a single ceramic sheet of 2 mm effects an escape of electrons and positrons

GEANT4 physics list QGSP_BIC_HP

energy spectrum of prompt γ-raysEp= 150 MeV; PMMA target

1.5 % electrons/γ

Page 8: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 8

X-Rays@Electron accelerator (ELBE)

X-Rays energy spectra ≤ 20 MeVpulse duration 5 psflux ≤ 500 kHz/cm2

Electron beammonoenergetic , single electrons energy 12 - 40 MeVpulse duration 5 psflux ≤ 500 kHz/cm2

Page 9: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 9

energy spectrum

X-Rays@ ELBE

beam size

Page 10: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 10

Beampipe

RPC

X-ray monitorLaBr; BGO

E γ<12.5MeV

FWHMRF = 94 ps

X-Rays@ELBE

Reference timing: ELBE RF

Trigger: RPCOR & RF

Event distribution

Page 11: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 11

Active area: 100 x 100 mm2 46 x 76 mm2

Bulk resistivity: ρ ~ 109 Ω cm ρ ~ 1012 Ω cmGas gaps: 2 x 2 gaps, 250 μm/gap 2 x 3 gaps, 250 μm/gap

Gas mixture: 85%Freon/10%i-Butane/5% SF6

Read-out electronics: GSI (FOPI)

L. Naumann et al., Nucl. Instr. Meth. A 628 (2011) 138 Kotte et al., Nucl. Instr. Meth. A 564 (2006) 155

RPC - design Ceramics RPC Glass RPC

Page 12: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 12

Glass RPC- timing

𝑡𝑇𝑜𝐹=𝑡 𝑙𝑒𝑓𝑡+𝑡 h𝑟𝑖𝑔 𝑡

2

𝜎𝑅𝑃𝐶+𝐹𝐸𝐸=√𝜎𝑇𝑂𝐹2 −𝜎𝑅𝐹

2

Average over the whole detector:

E = 103 kV/cm RPC+FEE = 160 psE = 107 kV/cm RPC+FEE = 161 ps

Page 13: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 13

Glass RPC – efficiency vs. flux

(6 gaps)

(4 gaps)

Eγ≤ 12.5 MeV

Page 14: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 14

Ceramics RPC – efficiency vs. flux

(4 gaps)

Eγ≤ 12.5 MeV

Page 15: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 15

RPC – efficiency

(6 gaps)

(4 gaps)

Eγ≤ 12.5 MeV

x 20

Page 16: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 16

Ceramics RPC – timing vs.flux

Page 17: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 17

• X-rays at ELBE are comparable to prompt gammas, generated by proton beams in human tissue

• GEANT4 simulations and experimental results of the detector efficiency have been compared. The results are in agreement for fluxes of 104 cm-²s-1 and amounts to 1.5 % per gap

• RPC with float glass electrodes shows in comparison to ceramics system an degradation of the rate capability by a factor of 20

• The time resolution is constant and amounts to FWKH = 150 ps up to the flux of 105 cm-²s-1

Conclusions

Page 18: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Dr. Lothar Naumann I [email protected] I Institut of Radiation Physics I www.hzdr.de Mitglied der Helmholtz-GemeinschaftSeite 18

20x20 cm²6 gas gaps, 250 μm/gap32 readout stripsPADI + VFTX

• Ceramics RPC for Prompt Gamma Timing

• Ceramics RPC for Prompt Gamma Imaging (slit camera system)

• Ceramics RPC test run with proton induced prompt gammas at OncoRay

Outlook

Page 19: Prof. Peter Mustermann | Institut xxxxx |  Seite 1 Dr. Lothar Naumann | Institute of Radiation Physics |  Timing RPC for prompt gamma

Prof. Peter Mustermann | Institut xxxxx | www.hzdr.deSeite 19

Dr. Lothar Naumann | Institute of Radiation Physics | www.hzdr.de

Acknowledgment:

HZDR - Dresden/Germany:A. Laso Garcia, J. Dreyer, B. Kämpfer, R. Kotte, H. Rohling, K. Römer, D. Stach, C. Wendisch

OncoRay - Dresden/Germany:G. Pausch

RPC 2016Lothar Naumann