Prof. Massimo Massi Benedetti

Chairman IDF European RegionDepartment of Internal Medicine -University of Perugia (I)

THE DIABETIC TIME BOMB

IN EUROPE

“Round Table”European Parliament Brussels

Members SalonTuesday 5th November 2002

THE INTERNATIONAL DIABETES FEDERATION

The mission of theInternational Diabetes Federation

is to work with our member associationsto enhance the lives of people with diabetes

IDF Regions

Total population: 655 millionsPeople with diabetes: 22.5 millionsMember associations: 59Countries represented: 41

IDF European Region

The estimated prevalence and numbers of type 2 diabetes mellitus by IDF region, year 2000

Differences in the prevalence of type 2 diabetes among selected ethnic groups

Prevalence in different countries in the year

0 2 4 6 8 10

Austria

Belgium

Denmark

Finland

France

Germany

Ireland

Italy

Netherlands

Poland

Spain

Sweden

Switzerland

UK

. (%)

1994 2000

Spain Sweden SwitzerlanUK6,1 6,4 3,7 3,5

Diabetes prevalence in different age classes

0

5

10

15

20

25

30

35

Finland Italy Sweden

45-54

55-64

65-74

75-

Pre

vale

nce

(%)

Age classes

Proportion of adolescent obesity

0

5

10

15

20

25

30

35

40

45

WhitesWhites BlacksBlacks AmericanAmericanIndiansIndians

% O

bese

% O

bese

Barry et al, J. Nutr. 1998Barry et al, J. Nutr. 1998

24.024.0

30.630.6

42.342.3

Estimates of magnitude of T2DM in North American children

StudyStudy YearYear AgeAgeEstimates*Estimates* (Years)(Years) (%)(%)

San Diego, CASan Diego, CA 19941994 0-160-16 88

Cincinnati, OHCincinnati, OH 19941994 0-190-19 1616

San Antonio, TXSan Antonio, TX 19971997 0-160-16 1818

Ventura, CAVentura, CA 19941994 0-170-17 45 45

Charleston, SCCharleston, SC 19971997 0-190-19 4646

*Percentage of T2DM among new cases of diabetes*Percentage of T2DM among new cases of diabetes

Impaired Glucose Tolerance

• IGT is characterised by raised blood glucose after meals (post-prandial hyperglycaemia), with near-normal fasting blood glucose

• IGT usually progresses to type 2 diabetes

Results from the Hoorn Study:• 28 % of the subjects with IGT at baseline

have developed type 2 diabetes within 2 years of study duration

• This is equivalent to a progression rate of 13.8% per year

Rate of progression of impaired glucose tolerance to type 2 diabetes

                                                     

Diabetes mellitusRegional estimates 1995 - 2025

0

10

20

30

40

50

60

70

801995 2000 2025

Africa Americas Eastern Europe South-Est Western Mediterranean Asia Pacific

Mill

ion

of i

ndi

vid

ual

s