SkinMedica® products are available exclusively through our dedicated network of licensed physicians and medically supervised spas.

PRODUCTGUIDE

Science of Beautiful Skin© 2011 SkinMedica, Inc. All rights reserved. PL1093-05

TNS® is covered by US Patent Nos. 6,372,494 and 7,118,746.MICROSPONGE® is a registered trademark of AMCOL International Corporation. This product is covered by U.S. Patent 5,851,538. The products described on this brochure meet the FDA’s definition of a cosmetic product and are intended to clean, beautify, promote attractiveness or alter your appearance. These statements have not been evaluated by the FDA. These products are not intended to be drug products that diagnose, treat, cure or prevent any disease or condition.

SkinMedica5909 Sea Lion Place, Suite HCarlsbad, CA 92010

Phone: 866.867.0110E-mail: info@skinmedica.comskinmedica.com

Use your smart phone to scan this code or visit skinmedica.com to learn more about the products.

Not all products are available in Canada. Subject to change at any time without prior notice.

THE SKINMEDICA® DIFFERENCE

At SkinMedica, we believe everyone deserves to have naturally radiant skin. That’s why we’ve dedicated years of research to effectively formulating technologically advanced skin care products for ultimate anti-aging skin rejuvenation.

Skin is capable of regenerating, healing and growing cells. When examined closely, there are many naturally occurring elements in young, healthy skin that provide tremendous regenerative benefits. SkinMedica believes that the main element is growth factors. Growth factors play an integral role in skin’s natural ability to repair damage and are key anti-aging actives in skin rejuvenation. Through meticulous research, we have been able to create a treatment regimen based on your skin condition and lifestyle that delivers optimal results for what your skin naturally craves.

SKIN CARE BASICS— TAKING THE RIGHT STEPSNo matter what your skin type, the principles remain the same. A twice-daily regimen of Cleanse, Tone, Skin Rejuvenation, Age Defense and Moisturize in coordination with Sun Protection during the day is essential for beautiful, healthy skin.

STEPS

ACNESkinMedica’s acne system employs therapeutic antiseptics to destroy bacteria, clean deeply, promote healing, and reduce breakouts on blemish-prone skin.

TONEpH balanced fresheners and clarifiers that gently tone and refine skin without depleting the natural oils of the skin.

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AGE DEFENSETreatment formulas suitable for all skin types that provide delivery of vital components to improve damage caused by exposure to the sun, environmental assaults and aging.

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SKIN REJUVENATIONRevolutionary anti-aging skin treatment serums formulated with naturally occurring growth factors, antioxidants, soluble collagen, cytokines and matrix proteins to rejuvenate skin.

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MOISTURIZEProducts with unique combinations of ingredients that work to provide a specific moisture level to help properly restore hydration and revitalize skin tone and texture.

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SUN PROTECTIONTriple Protection formulas—physical protection prevents UVA/UVB from entering the skin; chemical defense absorbs UVA/UVB; and potent antioxidants that protect the skin against free radical damage.

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CLEANSEGentle, non-irritating cleansers that purge skin of dirt, makeup, and environmental pollutants without damage to the skin’s moisture balance.

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VISIBLE REDNESSIntroducing Redness Relief CalmPlex™, clinically proven to reduce visible redness and promote healthy skin.

SPECIAL CONDITIONS

CLEANSE

SKIN POLISHER A physical exfoliator with ultra-fine jojoba spheres gently lifts dead cells from the skin surface without stripping moisture or over-exfoliating the skin. AM/PM

SENSITIVE SKIN CLEANSER Gently cleanses the most sensitive, post-procedure or inflamed skin with a combination of soothing botanical extracts. AM/PM

PURIFYING FOAMING WASHActive Ingredient: Salicylic Acid 2.0%

This instant foaming wash with salicylic acid helps remove excess oil and impurities to clear skin, break the chain of acne-producing comedones and prevent new acne blemishes. AM/PM

FACIAL CLEANSER This foaming, soap-free facial cleanser gently purges dirt, makeup, and environmental pollutants from the skin as it hydrates and refreshes. AM/PM

These gentle, non-irritating cleansers purge skin of dirt, makeup, and environmental pollutants without damage to the skin’s moisture balance, helping to achieve better absorption of other treatments.

PURIFYING TONERActive Ingredient: Salicylic Acid 2.0%

Purifies and refreshes skin with a combination of salicylic acid, tea tree oil, willow bark extract and other ingredients designed to reduce clogged pores and control breakouts often associated with acne or acne-prone skin. AM/PM

REJUVENATIVE TONER This refreshing, non-drying toner gently exfoliates dead skin cells and refines pores with mildly exfoliating alpha-hydroxy acids. AM/PM

These pH balanced fresheners and clarifiers gently tone and refine skin without depleting the natural oils of the skin.

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WHAT ARE GROWTH FACTORS AND HOW DO THEY WORK? • Growth factors are proteins that regulate cellular

growth and the activity of skin cells.

• There are different growth factors present in skin as a physiologically balanced combination to maintain a healthy skin structure.

• Through normal aging, the production and level of growth factors decreases, resulting in impaired skin repair, wrinkles and fine lines.

WHAT IS TNS®?Tissue Nutrient Solution (TNS) is a combination of growth factors and other naturally occurring elements that are crucial to the regeneration of healthy skin. TNS ESSENTIAL SERUM — BEFORE AND AFTER

(Applied twice daily)

TNS RECOVERY COMPLEX — BEFORE AND AFTER (Applied twice daily)

SKIN REJUVENATION

Individual results may vary.

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TNS ESSENTIAL SERUM®This patented treatment is the first and only anti-aging serum to combine the benefits of the proprietary growth factor blend, TNS Recovery Complex®, with potent antioxidants, peptides and other anti-aging ingredients to regenerate your skin. AM/PM

TNS RECOVERY COMPLEX®This unparalleled gel is the first and only patented anti-aging treatment using the highest level of a combination of growth factors clinically proven to improve the appearance of fine lines and wrinkles, skin tone, texture and elasticity. AM/PM

This vital step in the anti-aging process works with your skin’s natural cellular restructuring process to reducethe appearance of fine lines and wrinkles, diminish age spots, and improve skin texture and elasticity.

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HYDRATING COMPLEXA unique blend of high and low molecular weight hyaluronic acid to effectively replenish skin’s moisture reservoir, when used with your daily moisturizer. AM/PM

TRI-RETINOL COMPLEX 0.65% TOTAL RETINOIDS

Three forms of vitamin A in a sustained release formulation enhance skin texture through exfoliation and skin regeneration with minimal irritation. PM ONLY

VITAMIN C+E COMPLEX This silky, fragrance-free formula with 15% stabilized vitamin C and E provides extraordinary antioxidant protection, improving the appearance of skin tone, texture and firmness. AM/PM

These anti-aging treatments provide delivery of vital components to the skin to improve damage caused by exposure to the sun, environmental assaults and aging, and prevent additional damage.

FACE

AGE DEFENSE Step 4

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TRI-RETINOL COMPLEX ES™ 1.10% TOTAL RETINOIDS

This extra-strength treatment delivers three forms of vitamin A and contains the patented MICROSPONGE® delivery system to reduce the appearance of fine lines and wrinkles. PM ONLY

FACE

15% AHA/BHA CREAM This treatment with 15% alpha-beta hydroxy acids improves the appearance of skin texture, tone, and smoothness by exfoliating dead skin cells. AM/PM

TNS LINE REFINE® Visually reduces the appearance of fine lines and wrinkles around the mouth, eyes and crow’s feet while providing long-term anti- aging benefits, with the growth factor blend, TNS®, a patented anti-aging treatment. AM/PM

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TNS LIP PLUMP SYSTEM™The first and only clinically proven two-step lip treatment. Works to decrease the look of fine lines, improve contour and increase lip volume. As needed

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RESTORATIVE OINTMENT This ointment protects and accelerates the recovery of compromised skin immediately following ablative procedures such as laser resurfacing or deep chemical peels. AM/PM

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AGE DEFENSE

SYSTEMS

TNS REGENERATION SYSTEM® Combines the essential ingredients, vitamin C, vitamin A and growth factors to visibly reduce the signs of aging. Reveal healthy, glowing skin with this simple three step system. AM/PM

POST-PROCEDURE SYSTEM Specifically formulated to optimize the results from CO2 and fractionated CO2 laser resurfacing treatments and deep chemical peel procedures. AM/PM

HYPERPIGMENTATION SYSTEM – REGULAR STRENGTH This prescription strength anti- aging regimen lightens existing dark spots as it prevents further skin discoloration in a simple, easy-to-use, low-irritating professional system. AM/PM

HYPERPIGMENTATION SYSTEM – EXTRA STRENGTH This prescription strength anti-aging regimen lightens existing dark spots as it prevents further skin discoloration in a simple, easy-to-use professional system. AM/PM

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TNS EYE REPAIR®This luxurious eye treatment cream helps to increase firmness and elasticity, improve the appearance of fine lines and wrinkles and minimize dark circles. AM/PM MOISTURE LEVEL = 4

TNS ILLUMINATING EYE CREAM® This lightweight eye cream reduces the appearance of fine lines and dark circles with the growth factor blend, TNS®, a patented anti-aging treatment, peptides and chrysin. AM/PM MOISTURE LEVEL = 2N

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UPLIFTING EYE SERUM This oil-free serum soothes the delicate skin around the eyes to rapidly reduce the appearance of puffiness and fine lines. AM/PM MOISTURE LEVEL = 0A

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TNS IlluminatingEye Cream®

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BENEFITS OF OUR EYE PRODUCTS

PROFESSIONAL PEELS

ILLUMINIZE PEEL® • Non-invasive

• Increases skin glow and radiance

• Tightens the skin and restores a more youthful appearance

• Improves skin color, clarity and texture

• Little or no visible peeling

VITALIZE PEEL® • Non-invasive

• Well tolerated with little downtime

• Noticeable results after just one peel, significant results after 3–6 peels

• Helps to improve acne, hyperpigmentation, and melasma

• Smoothes fine lines and wrinkles

REJUVENIZE PEEL™ • Non-invasive

• Well tolerated with minimal downtime

• Noticeable improvement after just one peel, significant results after 3–6 peels

• Helps to improve acne and acne scarring

• Significant improvement in melasma and hyperpigmentation

• Smoothes fine lines, wrinkles, and rough textures

A chemical peel is a treatment performed by a medical professional in which an acid solution is used to treat and improve the skin by removing the damaged outer layers of the skin, enhancing and smoothing the texture. SkinMedica offers a comprehensive system of three peels, each designed to treat skin conditions from mild to severe, including photodamaged skin, fine lines and wrinkles, pigmentary abnormalities, acne scarring and acne. Ask your physician or skin care professional about SkinMedica’s in-office peels and accelerate your path to younger, healthier-looking skin.

REJUVENIZE PEEL — BEFORE AND AFTER

VITALIZE PEEL — BEFORE AND AFTER

Individual results may vary.

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FACE

DERMAL REPAIR CREAM This ultra-rich cream intensely hydrates and replenishes moisture to dry skin with high levels of lipid-soluble antioxidant vitamins C and E. AM/PM MOISTURE LEVEL = 4

TNS ULTIMATE DAILY MOISTURIZER™+SPF 20Enriched with the growth factor blend TNS® , a patented anti- aging treatment, and anti-oxidants, this formula guards against the destructive effects of free radical damage while also providing full-spectrum UVA/UVB protection. AM/PM MOISTURE LEVEL = 2

REJUVENATIVE MOISTURIZER This moisturizing cream with vitamins A, C and E soothes and hydrates stressed, dry skin. AM/PM MOISTURE LEVEL = 3

ULTRA SHEER MOISTURIZER This light, oil- and fragrance-free formula effectively hydrates skin while antioxidant vitamins C and E protect against free radical damage. AM/PM MOISTURE LEVEL = 1

Each product's unique combination of ingredients work to provide a specific moisture level based on your skin’s need, to help properly restore hydration and revitalize skin tone and texture.

MOISTURIZE

CERATOPIC® REPLENISHING CREAM Developed for tough treatment areas such as hands, feet, and elbows, this intense moisturizing cream restores the balance of ceramides and other lipids found in healthy skin. AM/PM MOISTURE LEVEL = 5

TNS BODY LOTION™This silky, emollient body lotion with the growth factor blend TNS®, a patented anti-aging treatment, hydrates, soothes and improves the appearance of dry, sun-damaged skin. AM/PM MOISTURE LEVEL = 4

TNS CERAMIDE TREATMENT CREAM™ This ceramide-rich treatment cream with the growth factor blend TNS®, a patented anti-aging treatment, and peptides rapidly restores the skin’s moisture balance while soothing and hydrating the driest, post-procedure and compromised skin. AM/PM MOISTURE LEVEL = 5

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Don’t let the environment affect the aging of your skin or increase your risk of skin cancer. Fight back against pollution, harmful chemicals, and UV exposure by limiting time in the sun, wearing protective clothing and using a SkinMedica® Triple Sun Protection formula—The first layer of physical protection prevents UVA/UVB from entering the skin; the second layer of chemical defense absorbs any UVA/UVB that enters the skin; and a third biological layer of potent antioxidants protects the skin against free radical damage.

ENVIRONMENTAL DEFENSE SUNSCREEN™ SPF 50+WITH UV Pro-Plex™ A very water-resistant, full-spectrum UVA/UVB defense sunscreen in an oil-free, paba-free and fragrance-free formulation. Ideal for extended sun exposure. Contains patented technology UV ProPlex™ to help improve performance requiring 25-30% less chemicals than other leading products.

ENVIRONMENTAL DEFENSE SUNSCREEN™ SPF 30+ An elegant, oil-free and fragrance-free sunscreen with advanced technology offering full-spectrum UVA and UVB protection with Z-COTE® Max™ and Parsol® MCX. Combined with antioxidant green tea as well as caffeine to protect the skin against free radical damage.

SUN PROTECTION Step 6

JOIN US IN THE FIGHT AGAINST SKIN CANCER!SkinMedica will make a $1 donation to Skin Cancer Awareness for each SkinMedica SPF product sold globally.

To learn more, visit www.skinmedica.com/fightskincancer

ACNE TREATMENT LOTION Active Ingredient: Benzoyl Peroxide 2.5%

This therapeutic lotion has the ability to reduce P. acnes bacteria as well as absorb sebum from the surface of the skin. AM/PM

SkinMedica’s acne sytem employs therapeutic antiseptics to destroy bacteria, clean deeply and reduce breakouts on blemish-prone or troubled skin.

ACNE

ACNE SYSTEMThis integrated acne treatment system utilizes the leading acne-fighting ingredients (salicylic acid and benzoyl peroxide) to control acne conditions and excess oil with minimal irritation — leaving clear, healthy skin. AM/PM

TAKING THE RIGHT STEPS TO CONTROL ACNE: 1. CLEANSE: Purifying Foaming wash

2. TONE: Purifying Toner

3. SKIN REJUVENATION: TNS Recovery Complex®

4. AGE DEFENSE: Hydrating Complex

5. TREAT ACNE: Acne Treatment Lotion

6. MOISTURIZE: Ultra Sheer Moisturizer

7. SUN PROTECTION: Environmental Defense Sunscreen™ SPF 30+

SPECIAL CONDITIONS

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Unretouched photographs of subjects at baseline and after twice daily use of Redness Relief CalmPlex.

Individual results may vary. 1Clinical studies on file at SkinMedica.

BENEFITS • Addresses the underlying causes of redness

• Clinically proven to reduce visible redness

• Fast-acting; initial results seen in as early as two weeks

• Restores skin’s barrier

• Non-comedogenic

• Leaves skin looking healthy and radiant

REDNESS RELIEF CALMPLEX™ This breakthrough treatment is clinically proven to reduce visible redness as well as address it's underlying causes. The addition of niacinamide helps to restore the skin’s barrier and promote healthy skin. Contains no added fragrance. Non-comedogenic. AM/PM

TAKE THE RIGHT STEPS TO REDUCE VISIBLE REDNESS:

1. CLEANSE: Sensitive Skin Cleanser

2. TONE: Unless you have very oily skin, toner should be avoided

3. SKIN REJUVENATION: TNS Recovery Complex®

4. AGE DEFENSE: Select based on your anti-aging skin care goals, excluding retinol products due to potential for increased irritation

5. MOISTURIZE: Redness Relief CalmPlex™

6. SUN PROTECTION: Environmental Defense Sunscreen™ SPF 30+

Some patients with sensitive skin may experience a momentary tingling sensation that subsides shortly after application and has been shown to decrease over time with continued usage.*

*Individual results may vary.

VISIBLE REDNESS

REDNESS RELIEF CALMPLEX — BEFORE AND AFTER

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Baseline Week 12

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Clinical studies demonstrated Redness Relief CalmPlex™ reduces the appearance of visible redness in two weeks with continued improvement over time.1

Dealing with visibly red skin can be frustrating. At SkinMedica® we understand and are proud to introduce Redness Relief CalmPlex™ - a breakthrough treatment clinically proven to be effective and fast-acting with initial results seen in as early as two weeks.