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Principles of Surveillance: Jonathan Samet, MD, MS 1 © 2007 Johns Hopkins Bloomberg School of Public Health Principles of Surveillance Jonathan Samet, MD, MS Johns Hopkins Bloomberg School of Public Health 2 © 2007 Johns Hopkins Bloomberg School of Public Health Learning Objectives Define the basic terms related to surveillance Specify characteristics of surveillance systems for different objectives Describe selected major surveillance systems

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Page 1: Principles of Surveillance - Global Tobacco Control · Obesity −Health behaviors Smoking, sexual behavior, substance use ©2007 Johns Hopkins Bloomberg School of Public Health 16

Principles of Surveillance: Jonathan Samet, MD, MS

1

© 2007 Johns Hopkins Bloomberg School of Public Health

Principles of Surveillance

Jonathan Samet, MD, MSJohns Hopkins Bloomberg School of Public Health

2© 2007 Johns Hopkins Bloomberg School of Public Health

Learning Objectives

Define the basic terms related to surveillance

Specify characteristics of surveillance systems for differentobjectives

Describe selected major surveillance systems

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3© 2007 Johns Hopkins Bloomberg School of Public Health

Uses of Morbidity and Mortality Data

1. Hypothesis generation

2. Health planning

3. Program evaluation

4. Surveillance

4© 2007 Johns Hopkins Bloomberg School of Public Health

Surveillance

“Ongoing, systematic collection, analysis, and interpretationof health-related data essential to the planning,implementation, and evaluation of public health practice,closely integrated with the timely dissemination of these datato those responsible for prevention and control.”

— U.S. Centers for Disease Control and Prevention

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5© 2007 Johns Hopkins Bloomberg School of Public Health

Information Loop of Public Health Surveillance

Source: adapted by CTLT from http://www.cdc.gov/epo/dphsi/phs/overview.htm

6© 2007 Johns Hopkins Bloomberg School of Public Health

Immediate Detection of . . .

Epidemics− Established agents− Emerging agents

Newly emerging health problems

Changes in health practices

Changes in antibiotic resistance

Chemical and biological terrorism

Source: Thacker and Stroup. (1994).

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7© 2007 Johns Hopkins Bloomberg School of Public Health

Periodic Dissemination for . . .

Estimating the magnitude ofthe health problem, includingcosts

Assessing control activities

Setting research priorities

Testing hypotheses

Facilitating planning

Monitoring risk factors

Monitoring changes in healthpractices

Source: Thacker and Stroup. (1994).

8© 2007 Johns Hopkins Bloomberg School of Public Health

Source: Thacker and Stroup. (1994).

Archival Information for . . .

Describing the natural history of disease

Facilitating epidemiologic and laboratory research

Validating the use of preliminary data

Setting research priorities

Documenting distribution and spread

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9© 2007 Johns Hopkins Bloomberg School of Public Health

Langmuir on Surveillance

“Surveillance, when applied to a disease, means thecontinued watchfulness over the distribution and trends ofincidence through the systematic collection, consolidation,and evaluation of morbidity and mortality reports and otherrelevant data.”

— Alexander Langmuir

10© 2007 Johns Hopkins Bloomberg School of Public Health

From Vector to Agent to Disease: Surveillance Points

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11© 2007 Johns Hopkins Bloomberg School of Public Health

Points for Surveillance Example: Tobacco

12© 2007 Johns Hopkins Bloomberg School of Public Health

Modeling a Surveillance System

Source: Teutsch and Churchill. (2000).

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13© 2007 Johns Hopkins Bloomberg School of Public Health

Surveillance Systems: Some Characteristics

Geographic scale: local to global

Event identification: active or passive

Scope: all or sentinel events

Focus on monitoring: vector → agent → outcome

Purpose: tracking or alarm

14© 2007 Johns Hopkins Bloomberg School of Public Health

Modeling a Surveillance System

Source: Teutsch and Churchill. (2000).

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15© 2007 Johns Hopkins Bloomberg School of Public Health

Occurrence of an Event: Kind of Event

What kind of an event?− Exposure

Exposure to air pollution, bio-monitoring− Disease

Communicable diseases, chronic diseases, syndromes− Injuries

Motor vehicle accidents, homicide− Health risk factors

Obesity− Health behaviors

Smoking, sexual behavior, substance use

16© 2007 Johns Hopkins Bloomberg School of Public Health

What do you want to do a surveillance of?− Exposure

Agents Biomarkers

− Exposure determinants Behaviors Risk factors Vectors Host characteristics Reservoirs

− Health outcomes Disease Death Medical care

Occurrence of an Event: Surveillance of What?

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WHO Global Tobacco Surveillance

World Health Survey− Household survey of adults (18+) conducted in 70 countries in

2002–2003

STEPwise Approach to Surveillance (STEPS)− Modular survey of chronic disease risk factors

Global Youth Tobacco Survey− School-based survey− Global Adult Tobacco Survey (planned)

18© 2007 Johns Hopkins Bloomberg School of Public Health

Occurrence of an Event: What Type of System?

What type of system would work best?− Universal: population tracking

Choose entire population or a representative sample tomonitor for condition of interest (measles, obesity,bioterrorism agents)

− Sentinel: “warning” signs Choose key “location” to monitor for condition of

interest (e.g., unusual disease) “Locations” might include sites, events, providers,

animals, vectors Choose a “location” that is most susceptible to change

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19© 2007 Johns Hopkins Bloomberg School of Public Health

Capturing an Event: Approaches

Active− Periodic solicitation of case reports from reporting sources,

such as physicians, hospitals, laboratories, etc.

Passive− Relies on health care providers to report on their own

initiative− Must make this reporting process simple and time efficient

20© 2007 Johns Hopkins Bloomberg School of Public Health

Active−Advantages

Can be very sensitive Can collect more

detailed information May be more

representative−Disadvantages

Costly Labor intensive Difficult to sustain

over time

Active vs. Passive: Advantages and Disadvantages

Passive−Advantages

Less costly Eager to design and

carry out Useful for monitoring

trends over time−Disadvantages

Low sensitivity Amount of data

available is limited May not be

representative

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Active: SEER Cancer Registry

Source: http://seer.cancer.gov

22© 2007 Johns Hopkins Bloomberg School of Public Health

Passive: CDC Notifiable Diseases

Provisional Cases of Selected Notifiable Diseases, United States,Week Ending July 16, 2005*

Source: U.S. Centers for Disease Control. (2005).

* Incidence data for reporting year 2005 is provisional

ChlamydiaAIDSReporting Area

Cum. 2004Cum. 2005Cum. 2004Cum. 2005

9,89110,433374386South Carolina

15,19817,485333531North Carolina

1,4931,3503036West Virginia

11,73210,550329307Virginia

1,9101,970355467District of Columbia

10,0099,692686812Maryland

1,5141,72980100Delaware

91,83090,6876,0226,473South Atlantic

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Modeling a Surveillance System

Source: Teutsch and Churchill. (2000).

24© 2007 Johns Hopkins Bloomberg School of Public Health

Processing and Analyzing the Event

How do you detect a signal?

Data capture/editing/management

Analytical approaches

Statistical approaches

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Examine the Event by Person, Place, and Time

By person: demographics, lifestyle, risk factors

By place: GIS mapping

By time: epidemic curve, time series analysis

26© 2007 Johns Hopkins Bloomberg School of Public Health

By Place: GIS Mapping

GIS: geographic information systems− GIS links location to information (such as people to addresses,

buildings to parcels, or streets within a network) and layersthat information to give you a better understanding of how itall interrelates

− You choose what layers to combine based on your purpose

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Image source: adapted by CTLT from U.S. Centers for Disease Control and Prevention. (2005).

By Time: Time Series

Time series analysis accounts for the fact that data points takenover time may have an internal structure (such as trend orseasonal variation) that should be accounted for

28© 2007 Johns Hopkins Bloomberg School of Public Health

By Person: Demographics

Age

Race/ethnicity

Occupation

Socioeconomic status

Sex

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By Place

Small areas

Governmental units

Nations

Unit chosen to examine is determined by the availability of dataon particular geographic scales

30© 2007 Johns Hopkins Bloomberg School of Public Health

Source: U.S. National Cancer Institute. (1999).

Cancer Mortality Rates, by State

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Heart Disease Death Rates: 1991–1995

Source: U.S. Centers for Disease Control and Prevention.

32© 2007 Johns Hopkins Bloomberg School of Public Health

Male Lung Cancer Incidence Rate per 100,000

Source: adapted by CTLT from GLOBOCAN. (2002). IARC.

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Female Lung Cancer Incidence Rate per 100,000

Source: adapted by CTLT from GLOBOCAN. (2002). IARC.

34© 2007 Johns Hopkins Bloomberg School of Public Health

Modeling a Surveillance System

Source: Teutsch and Churchill. (2000).

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Disseminating the Information

Process information for your audience− Broadcast faxes, email, mailings to dissemination lists

Locally, to clinicians Regionally, to health departments

− Web sites− Journal articles− Media

36© 2007 Johns Hopkins Bloomberg School of Public Health

Tobacco Use Information Systems

Global InfoBase− Data repository for chronic

disease risk factorprevalence, includingtobacco use

− Summarized inSurveillance of Risk FactorsReport (SuRF)

Global Information System onTobacco Control (GISTOC)− Provides links to tobacco-

related databases

Image source: World Health Organization. (2003 and 2005).

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World Health Organization: The SuRF Report

Source: The World Health Organization.

38© 2007 Johns Hopkins Bloomberg School of Public Health

Modeling a Surveillance System

Source: Teutsch and Churchill. (2000).

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Model for State-Based Chronic Disease Surveillance

Response

Hypothesis generation

Health planning

Program evaluation

Source: Remington and Goodman. (1999).

40© 2007 Johns Hopkins Bloomberg School of Public Health

Summary

Surveillance takeaways− Ongoing collection− Systematic according to a plan− Results given to those who need to know them− Resulting action is based in evidence gained in the

surveillance system