Principals of thermopuncture diagnosis, monitoring and treatment of patients with

diabetes.Valery Muzhikov, MD, Phd, CEO of “Med Byte” Ltd.

Mail: mujikov_v@mail.ru

“Home Doctor on a mobile phone

Gold medal - USA 2009Silver medal RAVI - Moscow 2009

Our history.We work on creation of devices for thermopunctur diagnostics and treatments with 1990г. For this time it is issued more than 10 versions of the professional devices. We have received 18 patents, 3 monographies and more than 40 publications are issued. Now under license contracts devices are certificated, made and sold in Europe, Asia, Australia and Russia.

1990 1993 1995 1996

2000

2004

1998

20072011

Description of the technology

• Our advantages:• Devices demand no special knowledge;• Gives a reliable result explained from the point

of view of modern physiology;• Easy to mass produce;• Opportunity to forecast a condition for the next

few days in order to address preventive treatment.

Over 15 years of work, we have created a new technology for diagnosis and treatment on the basis of the influence on certain information points on fingers modulated with IR-radiation. On the basis of this technology, we have created system estimations of the level of biochemical and physiological parameters of an organism calculated on the basis of individual mathematical models on the training gauging. The treatment is bloodless and painless and gives a predicted result after just 15-20 minutes.Simultaneously, with the help of an estimation of the individual biorhythms of separate organs it is possible to predict the condition of various parameters of an organism for the next few days.

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• Non-Invasive• Cost Effective• Accesible• DIY self administered solution

Solution

Basic principles of diagnosis1. Evaluation of pathology according to the channel map profile

•

The diagnosis of diseases and the control of the general condition are carried out on an estimation of structures of parameters on 12 basic physiological systems of an organism. Thus even simple visual estimation allows the features of each organism to be revealed.

Norm

Pancreatitis

Ischemia of a myocardium

Principles of diagnosis of diabetes on the profile test

Identified expressed statistically significant differences in the profiles of the test between the norm and diabetes of 1 and 2 types.

Basic principles of diagnosis 2. High correlation rate with blood sugar

• Type 2 diabetes, men – channel rates’• Correlation with blood sugar• n observation p p- criteria

• 1 143 .079 .940 .174 -.054 -.645 .260• 2 143 -.209 -2.538 .006* -.220 -2.681 .004*• 3 143 -.126 -1.512 .066 -.130 -1.561 .060• 4 143 -.129 -1.549 .062 -.158 -1.896 .030• 5 143 -.216 -2.630 .005* -.227 -2.774 .003*• 6 143 -.262 -3.230 .001* -.250 -3.066 .001*• 7 143 -.238 -2.905 .002* -.227 -2.770 .003*• 8 143 -.265 -3.259 .001* -.272 -3.359 .001*• 9 143 -.273 -3.374 .000* -.266 -3.273 .001*• 10 143 -.113 -1.354 .089 -.234 -2.853 .002*• 11 143 .071 .847 .199 -.076 -.910 .182• 12 143 -.297 -3.687 .000* -.323 -4.051 .000*• 13 143 -.079 -.939 .175 -.037 -.435 .332• 14 143 .046 .547 .293 -.049 -.579 .282• 15 143 -.024 -.290 .386 -.038 -.448 .327• 16 143 -.057 -.679 .249 -.160 -1.924 .028• 17 143 .128 1.532 .064 -.001 -.014 .494• 18 143 .193 2.335 .010* .023 .271 .393• 19 143 .045 .531 .298 -.006 -.069 .472• 20 143 .021 .252 .401 .060 .712 .239• 21 143 -.068 -.804 .211 -.104 -1.245 .108• 22 143 .208 2.524 .006* .070 .835 .203• 23 143 -.111 -1.330 .093 -.185 -2.238 .013*• 24 143 .128 1.527 .065 .032 .381 .352

Correlation with cholesterol

Basic principles of diagnosis• 3. Making individual and group models to control basic the parameters of the

organism

• Group model of correlation between blood sugar in patients with type 1 diabetes• ---------------------------------------------------------------------------------------------------------------• Channels coefficients mean error t-critic. significance level• ---------------------------------------------------------------------------------------------------------------• constant 23.881392 5.918608 4.0350 0.0005• RPs -6.106297 2.759818 -2.2126 0.0371• Fd 6.432937 1.32788 4.8445 0.0001• Ed -13.91464 4.019018 -3.4622 0.0021• Rd -4.004711 1.893141 -2.1154 0.0454• RPd 5.202921 1.436439 3.6221 0.0014• ---------------------------------------------------------------------------------------------------------------• R-SQ. (ADJ.) = 0.7522 SE= 8.393783 MAE= 5.667226 DurbWat= 1.814• Previously: 0.4522 12.480549 7.979804 1.556• 54 observations fitted, forecast(s) computed for 0 missing val. of dep. var.

• +Data Mining (Accuracy 0,8-0,9)• + NGO (Accuracy 0,7-0,85)

Basic principles. Individual control of harmony in the body at the level of the "Golden sections” and energy of the

Monad.

Оn 1997, we established (patent RU N 2198600), that the matrix of correlation inter-relations in channels, as a rule, has a certain structure, which corresponds to the concept of ancient Chinese MONAD (Yin/Yan) In healthy people this ratio corresponds to the ratio of the Golden section (1,62), and maintains the harmony of the soul and flesh in the body. With the help of our system influents of heat on the individual points can support individual monad in an optimal state. Then our desires will be in harmony with the possibilities and in this case, the life expectancy and quality will increase. This methodology harmonization body was tested on thousands of patients in Russia

Basic principles of diagnosis.5.The system of assessment of activity of the organism, depending on the age dipole

model.

The two graphs show the change in the activity of the TCM bioenergy Monad (dipole) of the body depending on the age of the choice of 250 men and 250 women. In old age is a violation of the «Golden section» and the alignment of the monad is a 50/50 that is accompanied by inhibition of all body functions. Maximum «heyday» of the organism occurs when there is an imbalance in the dipole, but the proportions of «the Golden section». In women the maximum surge of bioenergy is observed at about age 30, men in 20-25 years. Women have a period of inactivity in 40-50 years, associated and climax. In both cases, the impact of biorhythms with a period of about 7 years, through which the organism becomes more vulnerable to diseases. Using the factor analysis, and regression we established that the activity of the Monad depends mainly on the channel bladder (Bl), but men can influence only his right branch (Blr), , and women - left branch of this canal (Bll), . Thus, using a patented technique impact on this channel can be maintained bioenergy body and quality of life at the optimal level, even in old age.

Fire

Small Intestine Triple Heater

HeartPericardium

Stomach

Spleen

Large Intestine

Lung

Bladder

Gall Bladder

Liver

Earth

MetalWater

Wood

Kidney

Fire

Small Intestine Triple Heater

HeartPericardium

Stomach

Spleen

Large Intestine

Lung

Bladder

Gall Bladder

Liver

Earth

MetalWater

Wood

Kidney

+Fire

Water-

AP = 9+19+23+9 = 60Ht Si TH HC

Bladder + KidneyAP = 67+27 = 94

94/60=1.60

38%

62%

+Fire

Water-

AP = 9+19+23+9 = 60Ht Si TH HC

Bladder + KidneyAP = 67+27 = 94

94/60=1.60

38%

62%

Three levels control of the energy Chi:

1.Control balance of Yin/Yang energy level dipole (Fire/Water) allows you to maintain a General balance in the body. You should try to keep it in the level "Golden section“. 2.Control balance-Right/Left allows you to control the metabolism and maintain optimum BMI. 3.Balance control Right/Left at the level of 12 channels allows early diagnosis of diseases and implement targeted treatment on the level of Chi

The 12 main ACs form the system of the 5 Elements which are responsible for the general balance of

energy distribution in the body through stimulating and

inhibiting interactions between the organs.

The 12 main ACs form the system of the 5 Elements which are responsible for the general balance of

energy distribution in the body through stimulating and

inhibiting interactions between the organs.

Basic principles of diagnosis 4. Estimation of specific features of an organism and mechanism indemnification in type 1 diabetes

• Normn Norm

Amosov. Norma

0

2

4

6

8

10

12

14

16

Anna. Diabetes I

0

2

4

6

8

10

12

14

16

Borgest. Diabetes I

0

2

4

6

8

10

12

14

16

Ñðåäí èå ñ î ø èáêàì è èñõî äí û õ ï î ðî ãî â ÷óâñòâèòåëüí î ñòè(í å í î ðì èðî âàí í û õ í à ñóì ì àðí û å äàí í û å)

Norm

Type 1 diabetes with don't preserved-function B-cells

Type 1 diabetes with preserved-function B-cells. These patients were selected on the basis of the test and may be included in the basic research. They are most likely to respond to Leptin treatment and most effectively carry out the forecast state based on an assessment of pancreas biorhythms.

Structures of activity of channels

Simple way of testing the organism at the level of its separate physiological systems based on an assessment of loss of symmetry. The example of the pancreas (RP) has proved that the temperature pain barrier of the right channel's branch reflects

the total activity of B-cells and the left one – for A-cells

This principle works at the level of all channels, due to its universal nature.

А-cells

Method of achieving quantitative assessment of the features of the principal organism.Blood sugar level assessment according to the degree of the channels’ misalignment.

dRight

sLeft

11 9

48 6

10 24

6Test of pancreas (RP)

The presence of this atypical test asymmetry along with high levels of blood sugar points to insulin resistance. In these patients, an increase in the level of sugar is due to the high activity of A-cells that produce the contra insulin hormone (Glyukogon). These patients will display the best responses to treatment with Leptin.

Typical type 1 diabetes with partial preservation of function B-cells.

Norm

Assessing the biorhythmic activity of organs and the physiological system

1

X Data

0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38

Y D

ata

0.0

0.5

1.0

1.5

2.0

Fire/Water_d Fire/Water_s

2

X Data

0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36

Y D

ata

0.0

0.5

1.0

1.5

2.0

2.5

3.0

3

X Data

0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 40 42 44

Y D

ata

0.0

0.5

1.0

1.5

2.0

2.5

3.0

Äè í àì è ê à î òí î ø åí è é Fire/Water_d & Fire/Water_s â çàâè ñè ì î ñòè î ò í î ì åðà è çì åðåí è ÿ

The biorhythmic activity of the pancreas, liver and kidneys over 38 days based on the results of our tests.

The principal of generating biorhythms in the organ and its channel

Norm∆t>0

∆t=0

The organ does not work

Basic principals of working system - prognosis of condition organ

Prognosis

Real gauging

Biorhythm

real time at this moment

Basic principal of working system - prognosis of the condition of organs

T1Rp=5Vbs=16Sugar=6мМoll/l

T2Rp=8Vbs=20Sugar=23 мМоll/l

MODEL: glucose = 8,6xRpd – 2,3xVBs

At different times of the day, due to the varied activity of organs under the action of biorhythms, the blood sugar level also changes.When estimating a biorhythm, it is possible to predict the change in sugar for the next 1-2 days.

19

The concept of displaying the information to the user

Diabetes 1 type

Left Right

Sugar

- +Norma

SPSP

Time12:30

Sugar prediction

+

-Norma

The screen does not show absolute numerical values of glucose. The level of glucose is shown on a colour scale of varying intensity, as on the diagram. Thus, the device is not a means of metrology, and only shows the tendency in sugar change (much, very much or a little). As required, the user is able to place individual marks on the screen. Furthermore, as soon as a set of sufficient statistics is available, the device can be positioned individually as a glucometer.

high levellow level

20

The concept of displaying the information to the user

Type 2 diabetes

Time12:30

Sugar prediction

+

-Norma

Sugar

- +

Norma

Right

LeftSTSILIVGBDI

LILIVGB

The activity of each organ in an individual model contributes to the formation of blood sugar levels.

The concept of displaying the information to the user Type 1 diabetes

Time

Sugar prediction

+

-Norma

F diabetes .irst type insulin. Influence of doze

Time

Time12:308:00 14:00

5 units5 units

10 units10 units

The device can be equipped with a system for calculating an optimum dose of insulin and the time of optimum introduction. Diagrams of influence of different doses can be submitted to the user and to his/her doctor for download from the internet. This allows one doctor to supervise the condition of 30-40 patients through the special PC programme on a daily basis.

Су-Джок терапия острых болевых синдромов

При наличии болевых синдромовв различных частях тела и органах -нашим прибором можно эффективноснимать боль, воздействуя на определённые зонына ладонях

Huge and Growing Target Market

According to Nutrition Business journal annual revenue of TCM in 2007 is $4.7B from which $4.2B is acupuncture.

Health conscious consumers

Preventive Medical Practitioners• Acupuncturists• Yoga Teachers• Reiki Masters• Naturopaths• Osteopaths

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ChiMaster™ getchimaster.com

Business Model$99 for the ChiMaster™ Pen

- Lifetime access to Basic Plan for assessment

reports on Web and Mobile

- Access to TCM forum

$14.99 per month for Premium Plan

- In-depth assessment reports from our Reporting

Engine

- Monthly 1-on-1 Video Call with a TCM expert

System pulse - diagnosis on the basis of three-dimensional analysis of the heart rhythm

Further development of the systemIn the past, Chinese doctors defined the conditions of various organs on the basis of pulse diagnosis. We can also do this by means of pulse diagnosis using a measurement of temperature sensitivity. We developed this system 12 years ago, but its realisation at the time was dependent on a powerful computer and specialised knowledge. Now, the modern mobile phone allows basic calculations to be performed, with periodic transmission of data to a server. Thus, if this principle is realised, the information concerning the activity of different organs will be transmitted to the phone via sensors measuring heart contractions (for example from a special watch (“POLAR”) for controlling the heart rhythm). These data will be processed on individual models on the basis of periodic calibration of the system. In this case, the activity of the channels will be continuously estimated in real time, without the need for frequent gauging.

Rhythm of heart contractions

The special 3D spectral analysis of heart rhythm.

Heart rhythm spectral component estimation system

Diagram of organ activity over time

Numerical value of organ activity at the present time

17 Patents