Gitanjali Gitanjali 11

Preparing a Power Point Preparing a Power Point PresentationPresentation

GitanjaliGitanjali BatmanabaneBatmanabane

Gitanjali Gitanjali 22

What I shall cover ….What I shall cover …. Preparing a text slidePreparing a text slide Adding photos, clipart, soundsAdding photos, clipart, sounds Animating to illustrate mechanisms of Animating to illustrate mechanisms of

actionaction Making your presentation much more Making your presentation much more

interestinginteresting

Gitanjali Gitanjali 33

What I shall What I shall notnot cover… cover…

Font / size / typeFont / size / type How many lines to a slideHow many lines to a slide Backgrounds, what colour to chooseBackgrounds, what colour to choose Making a slide / saving itMaking a slide / saving it

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Text materialText material

Slide should have a title – use larger font orSlide should have a title – use larger font or different colour or capitals for titledifferent colour or capitals for title Write points below using key words or Write points below using key words or telegraphic languagetelegraphic language Use another colour or smaller fontUse another colour or smaller font Font size no less than 24Font size no less than 24

The functions of epidermal The functions of epidermal growth factor in normal cellsgrowth factor in normal cells

Cell ProliferationCell Proliferation AngiogenesisAngiogenesis Anti apoptosisAnti apoptosis

The functions of epidermal The functions of epidermal growth factor in normal cellsgrowth factor in normal cells

Cell ProliferationCell Proliferation AngiogenesisAngiogenesis Anti apoptosisAnti apoptosis

The functions of epidermal The functions of epidermal growth factor in normal cellsgrowth factor in normal cells

Cell ProliferationCell Proliferation AngiogenesisAngiogenesis Anti apoptosisAnti apoptosis

The functions of epidermal The functions of epidermal growth factor in normal cellsgrowth factor in normal cells

Cell proliferationCell proliferation AngiogenesisAngiogenesis Anti apoptosisAnti apoptosis

Epidermal Growth Factor40A

Gitanjali Gitanjali 99

How to search for an appropriate How to search for an appropriate image?image?

Make your own collectionMake your own collection Clipart CDs availableClipart CDs available Photos on CDsPhotos on CDs Spend time searchingSpend time searching Don’t use irrelevant picturesDon’t use irrelevant pictures

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How to search for an appropriate How to search for an appropriate image?image?

The web is a very rich sourceThe web is a very rich source Search for clipart on the webSearch for clipart on the web Use Google image search

Gitanjali Gitanjali 1111

How to insert an image from How to insert an image from Google image?Google image?

Type the word that best describes the imagType the word that best describes the image you want – e.g. capsulee you want – e.g. capsule

Double click the imageDouble click the image

If the word is non-specific the search will notIf the word is non-specific the search will not be focused – e.g. clipart be focused – e.g. clipart

The functions of epidermal The functions of epidermal growth factor in normal cellsgrowth factor in normal cells

Cell proliferationCell proliferation AngiogenesisAngiogenesis Anti apoptosisAnti apoptosis

40A

Epidermal Growth Factor

Epidermal Growth Factor Receptor

The functions of epidermal The functions of epidermal growth factor in normal growth factor in normal cellscells

Cell proliferationCell proliferation AngiogenesisAngiogenesis Anti apoptosisAnti apoptosis

1515

TK

EGF Function in Normal CellEGF Function in Normal Cell

TKATP ATP

Cell Proliferation Antiapoptosis

Angiogenesis

Gene Transcription

Cell Cycle Progression

+

Slide made by: Dr. M. Jayanthi

Cell membrane

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Another exampleAnother example

Teaching the coagulation cascade….Teaching the coagulation cascade….

1717

FibrinFibrin

Coagulation PathwayCoagulation Pathway

Extrinsic pathway (Tissue factor)

Prothrombin Thrombin

Fibrinogen

Intrinsic pathway (Contact)

X XaXa

XaXa

ThrombinThrombin

1818

FibrinFibrin

Coagulation PathwayCoagulation Pathway

Extrinsic pathway (Tissue factor)

Prothrombin Thrombin

Fibrinogen

Intrinsic pathway (Contact)

X XaXaXaXa

ThrombinThrombin

Slide prepared by C.GirishSlide prepared by C.Girish

1919

XIIXII

Contact (eg: with glass)Contact (eg: with glass)

XIIaXIIa

XIXI XIaXIa

IXIX IXaIXa

XX XaXa

VIIIaVIIIa

PLPL

CaCa++++

Intrinsic Pathway

Slide prepared by C.GirishSlide prepared by C.Girish

2020

Tissue factor (TF)Tissue factor (TF)

VIIVII VIIa- TFVIIa- TF

IXIX IXaIXa

XX XaXa

XIaXIa

VIIIaVIIIa

Extrinsic Pathway

Slide prepared by C.GirishSlide prepared by C.Girish

Gitanjali Gitanjali 2121

Levodopa(Prodrug)

DopamineDOPA

decarboxylase

2222

EGFR - Variant III EGFR – Wild Type

No extracellular domain Present

Ligand cannot bind Can bind

TK constitutively active TK activated by ligand binding

Cannot dimerise Can dimerise

Not found in normal cells Found normally

More propensity for cancer Up regulation leads to cancer

How EGFR variant differs from the wild type

2323

EGFR - Variant III EGFR – Wild Type

No extracellular domain Present

Ligand cannot bind Can bind

TK constitutively active TK activated by ligand binding

Cannot dimerise Can dimerise

Not found in normal cells Found normally

More propensity for cancer Up regulation leads to cancer

How EGFR variant differs from the wild type

Gitanjali Gitanjali 2424

How to animate a molecule How to animate a molecule getting bound to a receptor?getting bound to a receptor?

Draw a shape – rectangleDraw a shape – rectangle Insert another shape into the firstInsert another shape into the first Create one more shape of similar size & Create one more shape of similar size &

appearanceappearance Define the motion pathDefine the motion path Fine tuneFine tune

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What are the tasks?What are the tasks?

Group 1 & 2Group 1 & 2 Instructions : Prepare a slide for the given Instructions : Prepare a slide for the given

informationinformation