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2015Laboratory

Staying Ahead of Threats

Response NetworkN A T I O N A L M E E T I N G

Atlanta, GASEPTEMBER 9–11, 2015Tom Harkin Global Communications CenterCENTERS FOR DISEASE CONTROL AND PREVENTION

PREPARE

D E T E C T

RESPOND

Table of Contents

Meeting Goals and Objectives . . . . . . . . . . . . . . . . . . . . . . . . . . .2

Welcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3

LRN National Meeting Planning Committee . . . . . . . . . . . . . . . . . .4

Location Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9

General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10

Check-In and Information Desk Hours . . . . . . . . . . . . . . . . . . . .10

Continuing Education Credit Information . . . . . . . . . . . . . . . . . . .10

About LRN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11

About APHL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11

About CDC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11

Meeting at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17

Program Day 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21

Program Day 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27

Program Day 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37

List of Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43

Acronyms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .51

Blank Note Pages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .55

2 LRN 2015: Staying Ahead of Threats

Meeting Goals and Objectives

The Centers for Disease Control and Prevention (CDC) Division of Preparedness and Emerging Infections (DPEI) and the National Center for Environmental Health (NCEH) in collaboration with the Association of Public Health Laboratories (APHL) is pleased to convene the 2015 Laboratory Response Network (LRN) National Meeting from September 9-11, 2015 in Atlanta, GA .

The purpose of this meeting is to provide LRN stakeholders with current information on:

■■ Preparedness Collaborations

■■ Emerging Technologies

■■ Biosafety and Biosecurity

■■ Model Practices

■■ Solutions to Ongoing Challenges

■■ Training Needs

■■ Response Capabilities

■■ Future of the LRN

The LRN National Meeting is an ideal combination of science, policy, networking and partnerships, with a focus on innovation and emerging technologies .

LRN 2015: Staying Ahead of Threats 3

Dear Colleagues:

On behalf of the 2015 Laboratory Response Network (LRN) National Meeting Planning Committee, I am pleased to welcome you to Atlanta. For the first time this meeting is being held on the campus of the Centers for Disease Control and Prevention (CDC) and we’re very grateful to CDC for being such welcoming hosts. For over 15 years, the LRN has set the precedent as an exemplary laboratory system

that is sustainable and capable of responding to and “Staying Ahead of Threats”, the theme for this year’s meeting.

When the committee started planning this meeting, Ebola was very much on everyone’s mind and it was a reminder to us all that threats, whether biological, chemical or radiological, are always on our doorstep. This year’s meeting is comprised of plenary sessions, breakouts, and poster presentations providing opportunities to network with colleagues and to learn about the critical functions of LRN member laboratories. It is well understood that the future of the LRN relies constantly on us strengthening partnerships and realizing the value of all the laboratories that comprise the LRN. Our agenda will focus on these partnerships, the capabilities we have built and on how best to sustain and enhance these LRN achievements in the future so that we can stay ahead of threats.

I would like to thank the Planning Committee for all of their efforts in developing this exciting program and to the abstract submitters, moderators and presenters for sharing their experiences and knowledge, as well as the Association of Public Health Laboratories (APHL) and CDC staff, LRN members and partners who assisted with logistics, including providing multi-media resources and tools, to help make this National Meeting a success. I would like to extend a special thank you to Mr. Tyler Wolford, APHL’s LRN Specialist for his hard work in all aspects of the meeting planning and coordination, and keeping the planning committee on target!

Again, welcome and enjoy your stay in Atlanta!

Andrew Cannons, PhD

Chair, LRN National Meeting Planning Committee


2015 LRN National Meeting Planning Committee

Planning Committee Chair

Andrew C. Cannons, PhD, HCLD/CC (ABB)Laboratory DirectorFlorida Department of HealthBureau of Public Health LaboratoriesTampa, FL

Planning Committee Members

Blevins, Patricia, MPHBioterrorism Laboratory CoordinatorSan Antonio Metropolitan Health DistrictSan Antonio, TX

Chaitram, Jasmine, MPH, MT (ASCP)Laboratory Preparedness and Response BranchDivision of Preparedness and Emerging InfectionsCenters for Disease Control and PreventionAtlanta, GA

Chaudhuri, Sanwat, PhDBureau Director, Chemical and Environmental SciencesUnified State Laboratories: Public HealthUtah Department of HealthTaylorsville, UT

Collopy, Maureen, MPH, MT (ASCP)Bioterrorism CoordinatorNew Hampshire Public Health LaboratoriesConcord, NH

Degeberg, Ruhiyyih, MPHSenior Specialist, Environmental HealthAssociation of Public Health LaboratoriesSilver Spring, MD

George, KarimAssistant DirectorKentucky Division of Laboratory ServicesFrankfort, KY

Ghuman, HarjinderChemical Terrorism Laboratory CoordinatorGeorgia Public Health LaboratoryDecatur, GA

Griffin-Thomas, Latoya, PhD, MSBioterrorism Response CoordinatorVirginia Division of Consolidated Laboratory ServicesRichmond, VA

Johnson, Rudolph PhDLaboratory Chief, Emergency Response Branch Division of Laboratory SciencesCenters for Disease Control and PreventionAtlanta, GA


Leonard, Pascale, PhDMolecular Biology Supervisor New Mexico Department of Health Albuquerque, NM

MacKeil-Pepin, KaraAssociate Specialist, Public Health Preparedness and ResponseAssociation of Public Health LaboratoriesSilver Spring, MD

Mangal, Chris, MPHDirector, Public Health Preparedness and ResponseAssociation of Public Health LaboratoriesSilver Spring, MD

Nauschuetz, William, PhDLab Biopreparedness Manager US Army Medical Command, Fort SamHouston, TX

Paquette, Nicholas, MS, MT (ASCP), CBSPMicrobiologistFederal Bureau of Investigation LaboratoryQuantico, VA

Reiter-Kintz, Wanda, PhDBioterrorism/Chemical Terrorism CoordinatorState Hygienic Laboratory at the University of IowaCoralville, IA

Rhodes, Blaine, MChEDirector, Office of Environmental Lab SciencesWashington Public Health LaboratoriesShoreline, WA

Saravia, StefanChemical Threat Preparedness CoordinatorMinnesota Public Health Laboratory DivisionSt . Paul, MN

Tran, Robert, PhDBioterrorism Response CoordinatorLos Angeles Public Health Laboratory Downey, CA

Amy Watson, PhDLRN-C Program CoordinatorCenters for Disease Control and PreventionAtlanta, GA

Wolford, Tyler, MSSpecialist, Laboratory Response NetworkAssociation of Public Health LaboratoriesSilver Spring, MD

Zanto, Susanne, MPH, MLS, SMDeputy Laboratory DirectorMontana Laboratory Services BureauHelena, MT

2015N A T I O N A L M E E T I N G

GENERAL INFORMATION

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Location InformationTom Harkin Global Communications CenterBuilding 19Centers for Disease Control and Prevention 1600 Clifton Road, N .E . Atlanta, GA 30333 USA404 .639 .3311


General Information

Event Check-In and Information Desk Hours

Located in the Tom Harkin Global Communications Center LobbyBuilding 19

Wednesday, September 9 8:00 a .m . – 5:00 p .m .

Thursday, September 10 8:00 a .m . – 5:00 p .m .

Friday, September 11 8:00 a .m . – 1:00 p .m .

Continuing Education Credits

APHL is an approved provider of continuing education programs in the clinical laboratory sciences through the American Society of Clinical Laboratory Science (ASCLS) P .A .C .E .® program . Contact hours are available for the entire conference . The contact hours to be awarded to participants who successfully complete the sessions are as follows: Day 1 of the conference—4 .25 contact hours, Day 2 of the conference (either Biological OR Chemical track and general track)—5 .5 contact hours and Day 3 of the conference—1 .5 contact hours, for a total of 11 .25 contact hours . Contact hours will only be provided for full day attendance . On Day 2 you can receive contact hours for EITHER the Biological or Chemical breakout track, not for both . You must sign in once each day on the sign-in sheets in front of the session room .

Tell Us What You Think!

We take your evaluation of the LRN National Meeting seriously . Please plan on providing your feedback in an online survey provided after the meeting via email . Your feedback is vital to helping us plan a better and more beneficial meeting in the future .

Emergency Procedures for Attendees

CDC and APHL encourage all attendees to review and be familiar with CDC emergency procedures, including emergency exits for all meeting rooms . Please pre-identify a location away from the Tom Harkin Global Communications Center where you and your colleagues will meet in the event of an emergency .


About LRN The Laboratory Response Network (LRN) was established in 1999 through a collaborative effort involving founding partners, CDC, FBI, APHL and DoD to ensure an effective laboratory response to bioterrorism . Today, the LRN is an integrated network of local, state and federal public health, hospital-based, food testing, veterinary, environmental testing and international laboratories providing laboratory diagnostics and capacity for biological and chemical threats and other public health emergencies . The LRN is a unique asset in the nation’s growing preparedness for biological and chemical threats . The linking of state and local public health laboratories, veterinary, agriculture, military and water and food testing laboratories is unprecedented .

About APHL APHL is a national non-profit organization dedicated to working with members to strengthen governmental laboratories that perform testing of public health significance . Working at the national and international level, APHL advances laboratory systems and practices, promotes policies that support laboratories as a vital component of the public health system, provides a nexus for crisis response and exchange among laboratory systems, and links APHL member laboratories with federal partners, including the CDC, the Environmental Protection Agency (EPA), the Food and Drug Administration (FDA), the United States Department of Agriculture(USDA), the Department of Homeland Security (DHS) and the Federal Bureau of Investigation (FBI) .

About CDC CDC is one of the major operating components of the Department of Health and Human Services (HHS) . CDC’s top organizational components include the Office of the Director, Coordinating Centers and Offices and the National Institute for Occupational Safety and Health . These components collaborate to create the expertise, information and tools that people and communities need to protect their health through health promotion, prevention of disease, injury and disability and preparedness for new health threats . In addressing the preceding components of health, decisions are based on scientific excellence, requiring well-trained public health practitioners and leaders dedicated to high standards of quality and ethical practice .


LRN Structure for Biological Threats Preparedness

The LRN for Biological Threats Preparedness (LRN-B) is composed of three levels: Sentinel, Reference and National Laboratories . Reference laboratories are further subdivided into Reference, Standard and Advanced . The following are the capabilities for each level:

National Laboratories: there are three national laboratories (1) Centers for Disease Control and Prevention, (2) United States Army Medical Research Institute for Infectious Diseases and (3) the Naval Medical Research Center . These laboratories have specialized testing capabilities (e .g . Biosafety Level 4 facilities, strain characterization) and provide test development and agent specific subject matter expertise which can be leveraged when needed by the network .

Reference Laboratories: over 130 laboratories, categorized as Reference, Standard and Advanced, provide testing for high priority threat agents in a variety of matrices . In addition to their testing function, these laboratories also conduct outreach to sentinel clinical laboratories, first responders and other partners .

Sentinel Laboratories: thousands of laboratories, notably hospital based, work closely with local and state public health and federal laboratories to recognize and rule-out potential biological threat agents and other emerging threats to public health . Sentinel laboratories are an integral part of the LRN with the system relying heavily on their ability to recognize rule-out and/or refer potential threats .


LRN Structure for Chemical Threat Preparedness

The LRN for Chemical Threats Preparedness (LRN-C) is composed of 53 laboratories and is categorized into three distinct levels: one, two and three . Starting with level three and building upward, each designation carries additional safety requirements and testing capabilities, in addition to the duties and requirements of the preceding level . The following are minimum capabilities required at each level:

■■ CDC Laboratories provide a high level of analysis, including a rapid toxicology screen to detect exposure to chemical threats . Further, they maintain a quality system within the LRN-C by developing methods and providing proficiency testing and exercises .

■■ Level 1 Laboratories provide surge capacity for CDC and can detect exposure to an expanded number of chemicals, including mustard agents, nerve agents and toxic industrial chemicals .

■■ Level 2 Laboratories are trained to detect exposure to a number of chemical threat agents, including cyanide, nerve agents and toxic metals .

■■ Level 3 Laboratories work with hospitals and first responders to maintain competency in clinical specimen collection, packaging and shipment .


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LRN 2015: Staying Ahead of Threats

Program At- A- Glance

Wednesday, September 9 Event Check-In and Badge Pick-UpWelcome AddressKeynote AddressPlenary SessionsPoster Session

Thursday, September 10 Event Check-InBreakout Sessions (Biological, Chemical/Radiological)Plenary Session

Friday, September 11 Event Check-InColor Guard CeremonyAwards CeremonyPlenary Session Closing Keynote


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LRN 2015: Staying Ahead of Threats

Wednesday, September 98:00 a .m . - 9:00 a .m . Arrive at Centers for Disease Control and

Prevention Campus

8:00 a .m . - 4:45 p .m . Event Check-In and Badge Pick-Up Tom Harkin Global Communications Center Lobby

C .E .U .s and Objectives 4.25 contact hours for today’s sessions (588-833-15)At the conclusion of Day 1, the participant will be able to:

■■ Describe the evolving role of the LRN and articulate its past accomplishments and future vision .

■■ Discuss how the LRN supports public health .

■■ Describe partnerships, coordination and response efforts involved in international and domestic laboratory preparedness .

Welcome and Opening Panel Plenary Session Auditorium B1/B2/B3

Panel:

9:00 a .m . - 10:30a .m . Andrew C. Cannons, Ph.D., HCLD (ABB), Planning Committee Chair, Laboratory Director, Bureau of Public Health Laboratories – Tampa, Division of Disease Control and Health Protection, Florida Department of Health

Elizabeth Franko, DrPH, Laboratory Director, Georgia Public Health Laboratory, Georgia Department of Public Health


Brenda Fitzgerald, MD, Commissioner and State Health Officer, Georgia Department of Public Health

Thomas Frieden, MD, MPH, Director, Centers for Disease Control and Prevention

David Nabarro, MSc, BM BCh, MFPHM, FRCP, Special Representative to the United Nations Secretary–General

10:30 a .m . - 10:45 a .m . Break Tom Harkin Global Communications Center Lobby

Future of the Laboratory Response Network Plenary Session Auditorium B1/B2/B3

Moderator: Jasmine Chaitram, MPH, MT (ASCP) Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention

Panel:

10:45 a .m . – 11:05 a .m . Joanne Andreadis, PhD, Senior Advisor for Laboratory Preparedness, Office of Public Health Preparedness and Response, Centers for Disease Control and Prevention

11:05 a .m . – 11:25 a .m . James L. Pirkle, MD, PhD, Director, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention

11:25 a .m . – 11:45 a .m . Julie Villanueva, PhD, Branch Chief, Laboratory Preparedness and Response Branch, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention

11:45 a .m . – 12:00 p .m . Questions/Answers


10:00 a .m . – 5:00 p .m . Posters Available for Viewing Tom Harkin Global Communications Center Lobby

12:00 p .m . - 1:30 p .m . Lunch Available for Purchase Tom Harkin Global Communications Center Lobby

12:30 p .m . - 1:30 p .m . Poster Presenters Available for Discussion

International Response to Chemical Weapons Plenary Session Auditorium B1/B2/B3

Moderator: Rudolph Johnson, PhD, Laboratory Chief, Emergency Response Branch, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention

1:30 p .m . - 2:00 p .m . International Response to Chemical Weapons Hugh Gregg, PhD, Head of Organisation for the Prohibition of Chemical Weapons Laboratory, Organisation for the Prohibition of Chemical Weapons

2:00 p .m . - 2:15 p .m . Questions/Answers

2:15 p .m . – 2:30 p .m . Break Tom Harkin Global Communications Center Lobby

FBI Partnerships to Respond to Threats Plenary Session Auditorium B1/B2/B3

Moderator: Nicholas Paquette, MS, Microbiologist, Hazardous Materials Science Response Unit, Federal Bureau of Investigation Laboratory

2:30 p .m . - 3:00 p .m . History of Powder Letters Sent via Mail Douglas Beecher, PhD, Science Lead, Chemical, Biological, Radiological, Nuclear Sciences Unit (CBRNSU), Federal Bureau of Investigation Laboratory


3:00 p .m . - 3:20 p .m . Big Data and Personal Health Information: National & Transnational Security Implications Edward You, MS, Supervisory Special Agent, Weapons of Mass Destruction, Federal Bureau of Investigation

3:20 p .m . – 3:30 p .m . Questions/Answers

3:30 p .m . – 3:45 p .m . Break Tom Harkin Global Communications Center Lobby

2014 Ebola Outbreak Response Plenary Session Auditorium B1/B2/B3

Moderator: Scott Hughes, PhD, Associate Director, Public Health Laboratory, New York City Department of Health and Mental Hygiene

Panel:

3:45 p .m . - 4:05 p .m . Grace Kubin, PhD, Director, Laboratory Services Section, Texas Department of State Health Services

4:05 p .m . – 4:25 p .m . Peter Iwen, MS, PhD, D (ABMM), Director, Nebraska Public Health Laboratory

4:25 p .m . – 4:45 p .m . Mark Wolcott, PhD, Director, Special Pathogens Laboratory, United States Army Medical Research Institute of Infectious Diseases


5:00 p .m . Adjourn Day 1

Note: When you exit CDC, please retain your meeting badge.


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Thursday, September 10

8:00 a .m . - 8:45 a .m . Arrive at Centers for Disease Control and Prevention Campus

8:00 a .m . - 5:00 p .m . Event Check-In and Badge Pick-Up

C .E .U .s and Objectives 4.0 contact hours for today’s Biological Breakout session (588-834-15)

At the conclusion of Day 2, the participant of the Biological Breakout session will be able to:

■■ Describe lessons learned from real cases and exercises .

■■ Describe new technologies and capabilities of the LRN for Biological Threats Preparedness (LRN-B) as well as initiatives for assay development .

4.0 contact hours for today’s Chemical Breakout session (588-835-15)

At the conclusion of Day 2, the participant of the Chemical Breakout session will be able to:

■■ Describe lessons learned from real cases and exercises .

■■ Discuss the concept of the LRN for Radiological Threats Preparedness (LRN-R) and the importance of partnerships for preparedness and threat response .

■■ Describe how laboratories are involved in radiological preparedness activities .

■■ Describe new technologies and capabilities of the LRN for Chemical Threats Preparedness (LRN-C) .


1.5 contact hours for today’s General session (588-836-15)

At the conclusion of Day 2, the participant of the General session will be able to:

■■ Outline biosafety and biosecurity practices as it relates to the select agent program .

■■ Discuss ways to implement effective biosafety and biosecurity programs within the laboratory .

■■ Describe the role of biosecurity for all-hazard preparedness and response .


LRN-B IN ACTION BREAKOUT SESSION Auditorium B3

Moderator: Patricia Blevins, MPH, LRN Laboratory Coordinator, San Antonio Metro Health District Laboratory, City of San Antonio Metropolitan Health District

9:00 a .m . – 9:20 a .m . LRN in Action: Local, State and National Response to the October Texas Ebola Outbreak Erin Swaney, Team Leader, Biothreat Team and Emerging Preparedness, Laboratory Services Section, Texas Department of State Health Services

9:20 a .m . – 9:40 a .m . Multifaceted Response to a Large-Scale Brucella species Laboratory Exposure Megan Price, PhD, Bioterrorism Molecular Senior Scientist, Virginia Division of Consolidated Laboratory Services, Commonwealth of Virginia Department of General Services


9:40 a .m . – 10:00 a .m . Testing for MERS-CoV, the Indiana Lab Story Judith Lovchik, PhD, D (ABMM), Assistant Commissioner, Laboratory Director, Indiana State Public Health Laboratory, Indiana State Department of Health

10:00 a .m . – 10:20 a .m . A Perfect Storm: LRN Laboratory Response to Simultaneous Plague & Tularemia Outbreaks During Challenging Circumstances Larry Sater, MS, Biological and Chemical Terrorism Response Coordinator, Security Officer, Laboratory Services Division, Colorado Department of Public Health & Environment

10:20 a .m . – 10:30 a .m . Questions/Answers

LRN-C IN ACTION BREAKOUT SESSION Auditoriums B1/B2

Moderator: Amy D. Watson, PhD, LRN-C Program Coordinator, National Center for Environmental Health, Centers for Disease Control and Prevention

9:00 a .m . – 9:25 a .m . LRN-C: Beyond Preparedness, Increasing Roles and Expanding Partnerships Stefan Saravia, MPH, Chemical Threat Preparedness Coordinator, Minnesota Public Health Laboratory Division, Minnesota Department of Health

9:25 a .m . – 9:50 a .m . A Triangulation Strategy Between CT/Poison Control/Hazmat Jason Mihalic, Chemistry Office Chief, Arizona Bureau of State Laboratory Services, Arizona Department of Health Services

9:50 a .m . – 10:15 a .m . Unknown Substance Training for HAZMAT Responders: Assessment and Laboratory Sample Collection Meshel Mork, MS, Senior Chemist, Wisconsin State Laboratory of Hygiene, University of Madison-Wisconsin


10:15 a .m . – 10:30 a .m . Questions/Answers

10:30 a .m- 10:45 a .m . Break Tom Harkin Global Communications Center Lobby

LRN-B Unusual Case Presentations Breakout Session Auditorium B3

Moderator: William Nauschuetz, PhD, Laboratory Biopreparedness Manager, United State Army Medical Command

10:45 a .m . – 11:05 a .m . Response to an Unknown Pulmonary Illness Incident with an Unexpected Outcome LaToya Griffin-Thomas, PhD, MS, Bioterrorism Response Coordinator, Virginia Division of Consolidated Laboratory Services, Commonwealth of Virginia Department of General Services

11:05 a .m . – 11:25 a .m . USAMRIID Ebola Response: Vaccine Interactions and Canines William Dorman, Biothreat Coordinator, US Army Medical Research Institute of Infectious Diseases

11:25 a .m . – 11:45 a .m . Domestic Response to the First Ebola Case Daniel Serinaldi, MT (ASCP), Bioterrorism Response Coordinator, Dallas County Health and Human Services


Radiological Preparedness and Response Breakout Session Auditoriums B1/B2

Moderator: David Saunders, PhD, Physicist, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention

10:45 a .m . – 11:05 a .m . Response to Nuclear Events-Lessons from Fukushima


Blaine Rhodes, MChE, Director, Office of Environmental Laboratory Sciences, Washington Public Health Laboratories, Washington State Department of Health

11:05 a .m . – 11:25 a .m . CDC Radiological Preparedness and Response Capabilities and the Potential for LRN for Radiological Preparedness Robert L. Jones, PhD, Chief, Inorganic and Analytical Toxicology Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention

11:25 a .m . – 11:45 a .m . Inorganic and Radiation Analytical Toxicology Branch (IRAT) Activities Deanna Jones, Research Chemist, Centers for Disease Control and Prevention


12:00 p .m . – 2:00 p .m . Lunch Off-Campus On Your Own

Developing New Assays and Technologies for the LRN-B Breakout Session Auditorium B3

Moderator: Brad Bowzard, PhD, Acting Team Lead, Bioterrorism Rapid Response and Advanced Technology Laboratory, Laboratory Preparedness and Response Branch, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention

2:00 p .m . – 2:20 p .m . The development and use of a C. perfringens assay for use as a positive extraction control Michael Perry, MS, Laboratory Supervisor, New York State Department of Health, Wadsworth Center

2:20 p .m . – 2:40 p .m . Performance Evaluation of the EndoPep MS Assay for Detection of Botulinum Neurotoxins


Susan Maslanka, PhD, Team Lead, National Botulism Laboratory, Centers for Disease Control and Prevention

2:40 p .m . – 3:00 p .m . Developing Variola Virus Specific qPCR Assays Yu, Li, PhD, Team Lead, Molecular Diagnostics, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention


Developing New Assays and Technologies for the LRN-C Breakout Session Auditorium B1/B2

Moderator: Thomas Blake, PhD, Research Chemist, Team Lead, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention

2:00 p .m . – 3:15 p .m . Benefits of Switching to High-Throughput Specimen Analysis for a CT Laboratory Luke C. Short, PhD, Supervisory Chemist, District of Columbia Public Health Laboratory, DC Department of Forensic Sciences

Development of Dichlorotyrosine as a Biomarker of Chlorine Exposure Brian Crow, PhD, Senior Method Development Scientist, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention

Methods Development toward the Detection of Soapberry Toxins in Human Urine Melissa Carter, PhD, Senior Method Development Scientist, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention


Untargeted Data-Dependent Acquisition of Analytes from Human Blood Products Confirming Exposure to Organophosphorus Nerve Agents Thomas P. Matthews, PhD, Research Chemist, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention

3:15 p .m . - 3:30 p .m . Break Tom Harkin Global Communications Center Lobby

Biosafety and Biosecurity Plenary Session Auditorium B3 Video Feed to Auditoriums B1/B2

Moderator: Michael Shaw, PhD, Senior Advisor for Laboratory Science, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention

3:30 p .m . – 5:00 p .m . Biosecurity and Catastrophic Preparedness Patrick Rose, PhD, Director, Pandemic and Catastrophic Preparedness, National Association of County and City Health Officials

Implementing an Effective Biosafety Program Michael Pentella, PhD, MS, D (ABMM), William A. Hinton State Laboratory Institute, Massachusetts Department of Health and Human Services

Laboratory Bio-Risk Management Reynolds M. Salerno, PhD, Senior Manager, Biological Sciences and Technologies, Sandia National Laboratories

Federal Select Agent Program Robbin S. Weyant, PhD, Director, Division of Select Agents and Toxins, Centers for Disease Control and Prevention


5:00 p .m . Adjourn Day 2

Note: When you exit CDC, please retain your meeting badge.


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Friday, September 11

8:00 a .m . - 8:45 a .m . Arrive at Centers for Disease Control and Prevention Campus

8:00 a .m . - 1:00 p .m . Event Check-In and Badge Pick-Up

C .E .U .s and Objectives 1.5 contact hours for today’s sessions (588-858-15)

At the conclusion of Day 3, the participant will be able to:

■■ Describe some of the challenges associated with developing a state-wide response plan with first responders .

■■ Describe the importance of laboratory findings for law enforcement investigations .

■■ Discuss technologies that are currently being used by first responders as well as the development of new field-based technologies .


Color Guard Ceremony Auditorium B1/B2/B3

9:00 a .m . – 9:15 a .m . Georgia State Defense Force

Essential Partnerships and Funding to Stay Ahead of Threats Plenary Session Auditorium B1/B2/B3

Moderator: Eric Blank, Dr.P.H., Senior Director, Public Health Systems, Association of Public Health Laboratories


9:15 a .m . – 10:00 a .m . Partnerships to Enhance the LRN Scott J. Becker, MS, Executive Director, Association of Public Health Laboratories

Importance of Federal Funding to Sustain the LRN Peter Kyriacopoulos, Senior Director, Public Policy, Association of Public Health Laboratories

Awards Ceremony Auditorium B1/B2/B3

Presenters:

10:00 a .m . - 10:45 a .m . Judith Lovchik, PhD, D(ABMM), Assistant Commissioner, Laboratory Director, Indiana State Public Health Laboratory

A. Christian Whelen, PhD, D(ABMM), Laboratory Director, Hawaii Department of Health State Laboratories

10:45 a .m . - 11:00 a .m . Break Tom Harkin Global Communications Center Lobby

Partnering to Evaluate Field Devices and Respond to Threats Plenary Session Auditorium B1/B2/B3

Moderator: Noel Stanton, MS, Wisconsin State Laboratory of Hygiene, University of Madison-Wisconsin

11:00 a .m . - 12:30 p .m . Evaluation of the use of Field-Based PCR as a Screening Tool for First Responders Christina Egan, PhD, CBSP, Chief, Biodefense Laboratory, New York State Department of Health, Wadsworth Center

Georgia’s Biological Threat Response Guidance for 1st Responders Daniel Polanski, Chemical, Biological, Radiological, Nuclear (CBRN) Coordinator, Georgia Department of Public Health


Stranger than Fiction: The Remarkable Saga of a Would-Be Terrorist in Northern Minnesota Maureen Sullivan, MPH, Emergency Preparedness Unit Supervisor, Minnesota Public Health Laboratory Division, Minnesota Department of Health

Joint Biological Threat Response System: An All-Hazards Approach to Responding to Suspicious Substances Cheryl Gauthier, MA, MT (ASCP), Director, Bioterrorism Response Laboratory, William A. Hinton State Laboratory Institute, Massachusetts Department of Health and Human Services

Closing Plenary Session Auditorium B1/B2/B3

12:30 p .m . – 1:00 p .m . Andrew C. Cannons, Ph.D., HCLD (ABB), Planning Committee Chair, Laboratory Director, Bureau of Public Health Laboratories – Tampa, Division of Disease Control and Health Protection, Florida Department of Health

1:00 p .m . Adjourn 2015 LRN National Meeting


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Poster Sessions

Tom Harkin Global Communications Center Lobby

To be displayed from Wednesday, September 9th at 10:00 a .m . to Friday, September 11th at 1:00 p .m . Poster presenters will be available for questions during lunch on Wednesday, September 9th from 12:30 p.m. – 1:30 p.m.

1. Chikungunya, a Vector Borne Emerging Threat

Samantha Tostenson, Research Microbiologist, United States Army Medical Research Institute for Infectious Disease

2. Evaluation of the BacterioScanTM Instrument for Rapid Antimicrobial Susceptibility Testing of Yersinia pestis and Bacillus anthracis

Julia Bugrysheva, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Christine Lascols, MS, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Linda Weigel, PhD, Team Lead, Centers for Disease Control and Prevention

3. The Design and Validation of Variola Virus Specific Diagnostic Assays

A. Kondas, Victoria Olson, PhD, Team Lead, Poxvirus Team, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Yu, Li, PhD, Team Lead, Molecular Diagnostics, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, J. Abel, K. Wilkins, Inger Damon, MD, PhD, Chief, Poxvirus Program, Captain, USPHS, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Jonathan Turner, MS, MB (ASCP), Poxvirus Program, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention


4. Clandestine Laboratories: Beyond Recreational Pharmaceuticals New York State Department of Health First Responder Training Program

Alan J. Antenucci, All-Hazards Training Coordinator, New York State Department of Health, Wadsworth Center, Biodefense Laboratory

5. Laboratory Response Network Chemical (LRN-C) Level 3 Resource Handbook

Jennifer Jenner, PhD, Chemical Threat Response Laboratory Coordinator, Massachusetts Department of Public Health, Nicole Gethin, MS, Chemical Threat Response Laboratory Assistant Coordinator, Massachusetts Department of Public Health, Teresa Miller, Chemical Threat Coordinator, Michigan Department of Community Health

6. Comparison of DNA Extraction Methods for Whole Genome Sequencing of Bacillus anthracis

Heather McLaughlin, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Amy Gargis, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Julia Bugrysheva, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Andrew Carter, MPH, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, David Sue, PhD, Microbiologist, Centers for Disease Control and Prevention, Linda Weigel, PhD, Team Lead, Centers for Disease Control and Prevention

7. EXPRESS—Exercise of Preparedness and Response System

Tina Fan, P.D, Research Scientist 1/Program Manager, Chemical Terrorism Laboratory, New Jersey Department of Health Public Health & Environmental Laboratories

8. Dallas County LRN: Ebola Response 2014

Daniel Serinaldi, MB (ASCP), LRN BT Coordinator, Dallas County Health and Human Services

9. Applications of Pyrosequencing Technology for Identification and Characterization of Burkholderia pseudomallei.

Nelson Delgado, PhD, D(ABMM), RBP, Research Scientist-1, BioThreat Response Laboratory Coordinator, ARO, New Jersey Department of Health Public Health & Environmental Laboratories, A. MacMillan, S.


DasGupta, H. Shah, Ondrea Shone, Research Scientist, New Jersey Department of Health Public Health & Environmental Laboratories, D. Galkowski

10. Laboratory Preparedness and Response to Ebola Virus in New York City

Scott Hughes, PhD, Associate Director, Public Health Laboratory, New York City Department of Health and Mental Hygiene

11. Biothreat Environmental Sample Collection Training for First Responders: Highlighting Local, State and Federal Partnerships

Mark Glazier, Director, Biological Preparedness, Laboratory Outreach, and Logistics, Indiana State Department of Health Laboratories

12. Analysis of Mercury in Urine by ICP-MS

David Freund MT(AMT), Medical/Clinical Specialist, Georgia Public Health Laboratory, Stacey Gonder MPH, MLS(ASCP), Medical/Clinical Specialist, Georgia Public Health Laboratory, Noemi Kalath MPH, MLS(ASCP), Medical/Clinical Specialist, Georgia Public Health Laboratory,

13. Enhancing Rapid Electronic Laboratory Reporting: Collaborative Efforts and Progress with LRN-LIMSi

Indira Srinivasan, PMP, IT Project Manager, Centers for Disease Control and Prevention, Emory Meeks, Branch Chief, Information Systems Branch,Division of Health Informatics and Surveillance, Center for Surveillance, Epidemiology, and Laboratory Services, Office of Public Health Scientific Services, Centers for Disease Control and Prevention (CDC), Jasmine Chaitram, MPH, MT(ASCP) Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infections, Jon Lipsky, MBA, PMP, Consultant, J Michael Consulting, Jason Scott, PMP, Project Manager, J Michael Consulting

14. Implementation of Homeland Security Exercise Evaluation Program (HSEEP) to Test Plans and Protocols in the Laboratory

Graciela Malave, MT, MLS(ASCP) CM, BT & CT Coordinator, Biological and Chemical Emergencies Laboratory of the Puerto Rico Department of Health


15. Comparative Study of a Lateral Flow Assay to the LRN Time-Resolved Fluorescence Assay for Screening of Ricin Toxin in Environmental Samples

Michael Perry, MS, Laboratory Supervisor, New York State Department of Health, Wadsworth Center

16. Implementing MALDI-TOF in the Public Health Laboratory for C. botulinum Neurotoxin Detection

Dominick Centurioni, MS, Research Scientist, New York State Department of Health, Wadsworth Center

17. LRN in the Community: Responding to Ebola

Valerie Requenez, MLS(ASCP), BT Coordinator, Corpus Christi-Nueces County Public Health Department Laboratory, Rachel Rios, MT(ASCP), Clinical Microbiologist, Corpus Christi-Nueces County Public Health Department Laboratory, Donna Rosson, MPH, MT(ASCP), Public Health Administrator, Corpus Christi-Nueces County Public Health Department Laboratory

18. Ebola Planning: The State Perspective.

Marissa Bloemke, LRN Molecular Biologist, Infectious Disease Section, Minnesota Public Health Laboratory Division

19. The Great Flood: A Real Life Game of “Whack-a-mole”.

Jackie Mahon, LRN Molecular Biologist, Infectious Disease Section, Minnesota Public Health Laboratory Division

20. From Threat to Reality: Biological and Chemical Emergencies Laboratory Response to Chikungunya virus

Gloriene González Ruiz, Biological and Chemical Emergencies Laboratory of the Puerto Rico Department of Health

21. All Hands on Deck: What Happens When There is Something in the Water

Courtney Demontigny, MS, LRN Molecular Assay Coordinator, Minnesota Public Health Laboratory Division


22. Leveraging the LRN: A Step Toward Implementing International Health Regulations (IHR) (2005)

Tyler Wolford, MS, Specialist, LRN, Association of Public Health Laboratories


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AcronymsAAVLD American Association of Veterinary

Laboratory Diagnosticians

AHRF Assessment of Health Risks with Feedback

AML Area Medical Laboratory

APHIS Animal and Plant Health Inspection Service

APHL Association of Public Health Laboratories

ASM American Society for Microbiology

ASTM American Society for Testing and Materials

BA Bacillus anthracis

BAIT Biological Agent Identification and Counterterrorism Training

BOTE Bio-Response Operational Testing Exercise

BRRATL Bioterrorism Rapid Response and Advanced Technology Laboratory

BSL Biosafety Level

BTRA Bioterrorism Risk Assessment

CAP College of American Pathologists

CBCT Confidence Building Competency Test

CBNR Chemical, Biological, Nuclear, and Radiological

CBRNSU Chemical Biological Radiological Nuclear Science Unit (FBI Laboratory)

CDC Centers for Disease Control and Prevention

CLIA Clinical Laboratory Improvement Amendments

CoC Chain of Custody

COOP Continuity of Operations Plan

CRCPD Conference of Radiation Control Program Directors

CRP Critical Reagents Program

CST Civil Support Team (U.S. Army National Guard)

CWA chemical warfare agents

DBPR Division of Bioterrorism Preparedness and Response

DEOC Director of the Emergency Operations Center (Federal)

DHS Department of Homeland Security

DHS OHA Department of Health and Human Services Office of Health Affairs

DHS S&T Department of Health and Human Services Science and Technology

DLN Defense Laboratory Network

DoD Department of Defense

DoD GEIS United States Department of Defense Global Emerging Infections Surveillance and Response System

DOE Department of Energy

DOJ Department of Justice

DSL Division of Laboratory Systems

DTRA Defense Threat Reduction Agency

EDD Electronic Data Deliverable

EPA Environmental Protection Agency

ERCL Emergency Response Chemical Laboratory

ERLN Environmental Response Laboratory Network

EUA Emergency Use Authorization

FBI Federal Bureau of Investigation

FDA Food and Drug Administration

FERN Food Emergency Response Network

FSIS Food Safety and Inspection Service

GC-MS Gas chromatography-mass spectroscopy

H1N1 Hemoagglutinine and Neuroaminidase Influenza Virus

HHA Handheld Assay

HHS Department of Health and Human Services

HMRT Hazardous Materials Response Team (FBI field hazmat teams)

HMSRU Hazardous Materials Science Response Unit (FBI Laboratory)

HSEEP Homeland Security Exercise and Evaluation Program

IAWG Interagency Working Group

IBRD Interagency Biological Restoration Demonstration

ICLN Integrated Consortium of Laboratory Networks


IRA Integrated Response Architecture

ISO ISO International Organization for Standardization

ITCC Information Technology Communication Committee

JBAIDS Joint Biological Agent Identification and Diagnostic System

JLC Joint Leadership Council

JPM CBMS Joint Program Executive Office for Chemical and Biological Medical Systems

LIMS/LIS Laboratory Information (Management) System

LIMSi Laboratory Information Systems Management integration

LLNL Lawrence Livermore National Laboratory

LPX Laboratory Preparedness Exercise

LRN Laboratory Response Network

LRN-B Laboratory Response Network for Biological Terrorism Preparedness

LRN-C Laboratory Response Network for Chemical Terrorism Preparedness

LRN-R Laboratory Response Network for Radiological Terrorism Preparedness

MCC Method Coordination Committee

MOU Memorandum of Understanding

MSDS Material Safety Data Sheet

NAHLN National Animal Health Laboratory Network

NCEH National Centers for Environmental Health (under CDC)

NCG Network Coordinating Group

NELAC National Environmental Laboratory Accreditation Conference

NGB National Guard Bureau

NIOSH National Institute for Occupational Safety and Health

NLTN National Laboratory Training Network

NMRC Naval Medical Research Center

NPDN National Plant Diagnostic Network

NRC Nuclear Regulatory Commission

OHA Office of Health Affairs

OIG Office of Inspector General

PCR Polymerase Chain Reaction

PHAA Public Health Actionable Assays

PHEP Public Health Emergency Preparedness

PHILIS Portable High Throughput Integrated Laboratory Identification Systems

PHLIP Public Health Laboratory Interoperability Project

PSAA Public Safety Actionable Assays

PT Proficiency Testing

QA Quality Assurance

QAPP Quality Assurance Program Plan

REEF Radiological Evidence Examination Facility

RT-PCR Real Time Polymerase Chain Reaction

SAIC Science Applications International Corporation

SAP Select Agent Program

SARS Severe Acute Respiratory Syndrome

SOW Statement of Work

STP Scenarios and Threat Prioritization

SVOC semi volatile organic compounds

USAHA United States Animal Health Association

USAMRIID U.S. Army Medical Research Institute for Infectious Diseases

USDA Department of Agriculture

VSP Validate Sampling Plan

WLA Water Laboratory Alliance

WMD Weapons of Mass Destruction

WMDC WMD Coordinator (FBI field office coordinator)

WMDD Weapons of Mass Destruction Directorate


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CS257147-I

prepare response network detect · biosafety and biosecurity model practices solutions to ongoing...

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