prediction of outcome after stroke

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Page 1: Prediction of Outcome After Stroke

Phys

Occ

up T

her

Ger

iatr

Dow

nloa

ded

from

info

rmah

ealth

care

.com

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rsity

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onal

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y.

Page 2: Prediction of Outcome After Stroke

Phys

Occ

up T

her

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iatr

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ded

from

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rsity

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onal

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y.

Page 3: Prediction of Outcome After Stroke

Phys

Occ

up T

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iatr

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ded

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Page 4: Prediction of Outcome After Stroke

Phys

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up T

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iatr

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ded

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Page 5: Prediction of Outcome After Stroke

TA

BLE

1.S

elec

tive

Sum

mar

yof

33S

tudi

esE

xam

inin

gP

redi

ctor

sof

Str

oke

Out

com

ein

Ter

ms

ofF

unct

iona

lSta

tus,

Dis

char

geS

ettin

g,an

dQ

OL

Pos

t-S

trok

e

Aut

hor/

sG

oalo

fstu

dy(r

elat

edto

this

revi

ew)

Stu

dysa

mpl

eT

imin

gO

utco

me

mea

sure

s(r

elat

edto

this

revi

ew)

Pre

dict

ors

(rel

ated

toth

isre

view

)R

esul

ts

Ale

xand

er(1

994)

To

diffe

rent

iate

betw

een

patie

nts

with

diffe

rent

func

tiona

lou

tcom

es

N=

520,

mea

nag

e=

72%

(L)/

(R)C

VA

=49

/51

Bra

inst

eman

dce

rebe

llar

stro

kes

excl

uded

Rev

iew

ofad

mis

sion

/di

scha

rge

data

Dis

char

gefu

nctio

n(F

IM)

and

setti

ngA

geS

ide

ofst

roke

Adm

issi

onfu

nctio

n

Adv

erse

effe

ct–o

lder

age,

(R)C

VA

(FIM

chan

geon

ly),

low

adm

issi

onfu

nctio

n

Bru

unW

ylle

ret

al.(

1997

)T

ost

udy

gend

erdi

ffere

nces

infu

nctio

nalo

utco

me

N=

87,m

ean

age

=75

%m

ale/

fem

ale

=52

/48

Infa

rctio

n=

87%

,he

mor

rhag

e=

7%,o

ther

=6%

7-16

days

afte

rad

mis

sion

,1

year

post

-dis

char

ge

Fun

ctio

n(B

arth

elIn

dex)

1ye

arpo

st-s

trok

ean

dse

tting

Gen

der

Adv

erse

effe

ct–f

emal

ege

nder

Col

anto

nio

etal

.(19

96)

To

dete

rmin

eph

ysic

alfu

nctio

npr

edic

tors

ofpo

st-s

trok

efu

nctio

nan

ddi

scha

rge

setti

ng

N=

79,a

ge:<

75(4

8%),

75-8

4(3

4%),

85+

(18%

)%

mal

e/fe

mal

e=

39/6

1P

revi

ous

stro

keex

clud

ed

Pre

-str

oke,

inho

spita

l,6

mon

ths

post

-dis

char

ge

Fun

ctio

n(K

atz)

and

setti

ng6

mon

ths

post

-dis

char

ge

Age

,gen

der

Str

oke

seve

rity

Com

orbi

dity

Cog

nitiv

eim

pairm

ent

No

effe

ct–g

ende

r,co

mor

bidi

tyA

dver

seef

fect

–old

erag

e(s

ettin

gon

ly),

stro

kese

verit

y,co

gniti

veim

pairm

ent(

setti

ngon

ly)

Col

anto

nio

etal

.(19

93)

To

dete

rmin

eps

ycho

soci

alpr

edic

tors

ofpo

st-s

trok

efu

nctio

nan

ddi

scha

rge

setti

ng

N=

127,

age:

<75

(42%

),75

-84

(38%

),85

+(2

0%)

%m

ale/

fem

ale

=44

/56

Pre

viou

sst

roke

excl

uded

Pre

-str

oke,

inho

spita

l,6

wee

kspo

st-d

isch

arge

Fun

ctio

n(K

atz)

and

setti

ng6

wee

kspo

st-d

isch

arge

Age

,gen

der

Soc

ialn

etw

ork

size

and

perc

eive

dso

cial

supp

ort

Str

oke

seve

rity

Com

orbi

dity

Cog

nitiv

eim

pairm

ent

No

effe

ct–g

ende

r,pe

rcei

ved

soci

alsu

ppor

t,co

mor

bidi

tyP

ositi

veef

fect

–soc

ialn

etw

ork

size

Adv

erse

effe

ct–o

lder

age

(set

ting

only

),st

roke

seve

rity

(fun

ctio

non

ly),

cogn

itive

impa

irmen

t

deH

aan

etal

.(19

95)

To

anal

yse

the

impa

ctof

stro

kety

pean

dlo

catio

non

QO

L

N=

441,

mea

nag

e=

73%

mal

e/fe

mal

e=

52/4

8%

(L)/

(R)C

VA

=54

/46

37%

prev

ious

stro

ke

Inho

spita

l,6

mon

ths

post

-str

oke

QO

L(S

IP)

6m

onth

spo

st-s

trok

eA

ge,g

ende

rS

ide

ofst

roke

Str

oke

seve

rity

Com

orbi

dity

Pre

viou

sst

roke

No

effe

ct–g

ende

r,pr

evio

usst

roke

Adv

erse

effe

ct–o

lder

age,

(R)C

VA

,str

oke

seve

rity,

com

orbi

dity

Frie

dman

(199

5)T

oex

amin

epr

edic

tors

ofre

turn

ing

hom

eto

live

alon

e

N=

178,

mea

nag

e=

76%

mal

e/fe

mal

e=

36.5

/63.

520

%pr

evio

usst

roke

All

prev

ious

lyliv

ing

alon

e

Day

7;1,

2,6,

and

12m

onth

spo

st-s

trok

e,di

scha

rge

Dis

char

gese

tting

(hom

eal

one

orno

t)A

ge,g

ende

rS

trok

ese

verit

yP

revi

ous

stro

keA

dmis

sion

func

tion

Men

tals

tatu

s

No

effe

ct–a

ge,g

ende

r,pr

evio

usst

roke

Adv

erse

effe

ct–s

trok

ese

verit

y,lo

wad

mis

sion

func

tion,

low

men

tals

tatu

ssc

ores

Gra

nger

etal

.(1

992)

To

exam

ine

pred

icto

rsof

disc

harg

efu

nctio

nan

dse

tting

N=

7905

,mea

nag

e=

71%

(L)/

(R)C

VA

=46

/43,

bila

tera

l=3%

,oth

er=

8%

Rev

iew

ofad

mis

sion

/di

scha

rge

data

Dis

char

gefu

nctio

n(F

IM),

rate

sof

com

mun

itydi

scha

rge

Age

Sid

eof

stro

keA

dver

seef

fect

–old

erag

e,bi

late

ralp

ares

is

Phys

Occ

up T

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iatr

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onal

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y.

Page 6: Prediction of Outcome After Stroke

TA

BLE

1(c

ontin

ued)

Aut

hor/

sG

oalo

fstu

dy(r

elat

edto

this

revi

ew)

Stu

dysa

mpl

eT

imin

gO

utco

me

mea

sure

s(r

elat

edto

this

revi

ew)

Pre

dict

ors

(rel

ated

toth

isre

view

)

Res

ults

Hei

nem

ann

etal

.(19

87)

To

iden

tify

patie

ntch

arac

teris

tics

asso

ciat

edw

ithfa

vour

able

outc

omes

N=

432,

mea

nag

e=

63%

mal

e/fe

mal

e=

55/4

5%

(L)/

(R)C

VA

=50

/46,

bila

tera

l=4%

Rev

iew

ofad

mis

sion

/dis

-ch

arge

data

,3

mon

thfo

llow

-up

Dis

char

gefu

nctio

n(b

ased

onB

arth

elIn

dex)

and

setti

ng3

mon

thfo

llow

-up

func

tion

Age

Gen

der

Sid

eof

stro

keA

dmis

sion

func

tion

No

effe

ct–a

ge,g

ende

r,si

deof

stro

keA

dver

seef

fect

–low

adm

issi

onfu

nctio

n(f

unct

ion

only

)

Her

rman

net

al.(

1998

)T

ode

term

ine

the

effe

cts

ofde

pres

sive

sym

ptom

son

stro

kere

cove

ry

N=

436,

mea

nag

e=

75%

mal

e/fe

mal

e=

49/5

1%

(L)/

(R)C

VA

=49

/49%

,bi

late

ral=

2%27

%pr

evio

usst

roke

Inho

spita

l,3

and

12m

onth

spo

st-s

trok

e

Fun

ctio

n(F

IM)

12m

onth

spo

st-s

trok

eD

epre

ssio

nA

dver

seef

fect

–dep

ress

ion

Joha

nsso

net

al.(

1992

)T

oev

alua

teth

em

edic

al&

soci

alou

tcom

eup

to1

year

post

-str

oke

N=

346,

age:

�75

(52%

)%

mal

e/fe

mal

e=

56/4

4%

(L)/

(R)C

VA

=46

/31,

othe

r=

16.5

%,p

revi

ous

stro

keex

clud

ed

With

in48

hour

sof

stro

keon

set,

6an

d12

mon

ths

post

stro

ke

Dis

char

gefu

nctio

n(8

AD

Lite

ms)

and

setti

ng,Q

OL

(NH

P)

Age

Sid

eof

stro

keA

dver

seef

fect

–old

erag

e(f

unct

ion

only

),(R

)CV

A

Jorg

ense

net

al.(

1995

)T

oev

alua

test

roke

outc

ome

acco

rdin

gto

initi

alst

roke

seve

rity

and

leve

lofd

isab

ility

N=

1197

,mea

nag

e=

74%

mal

e/fe

mal

e=

46/5

4In

farc

tion

=92

%,

hem

orrh

age

=8%

Inho

spita

l,di

scha

rge

and

6m

onth

follo

w-u

p

Dis

char

gefu

nctio

n(B

arth

elIn

dex)

and

setti

ng,6

mon

thfo

llow

-up

func

tion

Str

oke

seve

rity

Adm

issi

onfu

nctio

nA

dver

seef

fect

–str

oke

seve

rity,

low

adm

issi

onfu

nctio

n

Kal

ra(1

994)

To

stud

yth

ein

fluen

ceof

age

onpo

st-s

trok

eou

tcom

es

N=

245,

age:

<75

(41%

)%

mal

e/fe

mal

e=

43/5

7%

(L)/

(R)C

VA

=43

/48,

othe

r=

9%,1

3%pr

evio

usst

roke

Adm

issi

on,

wee

kly

inho

spita

l,di

scha

rge

Dis

char

gefu

nctio

n(B

arth

elIn

dex)

and

setti

ng

Age

Adv

erse

effe

ct–o

lder

age

Kal

raet

al.

(199

3)T

oid

entif

yfa

ctor

sw

hich

influ

ence

stro

keou

tcom

e

N=

96,m

ean

age

=81

(onl

yth

ose

>75

incl

uded

)%

mal

e/fe

mal

e=

28/7

2%

(L)/

(R)C

VA

=44

/48

Bra

inst

em/c

ereb

ella

rsi

gns

=8%

,19%

prev

ious

stro

ke

With

in72

hour

sof

adm

issi

on,

wee

kly

inho

spita

l,di

scha

rge

Dis

char

gese

tting

Age

,gen

der

Sid

e/se

verit

yof

stro

keC

omor

bidi

tyP

revi

ous

stro

keA

dmis

sion

func

tion

Men

tals

tatu

s

No

effe

ct–a

ge,g

ende

r,si

deof

stro

ke,c

omor

bidi

ty,p

revi

ous

stro

keA

dver

seef

fect

–sev

erity

ofst

roke

(inco

ntin

ence

only

),lo

wad

mis

sion

func

tion,

impa

ired

men

tals

tatu

s

Kel

ly-H

ayes

etal

.(19

88)

To

expl

ore

influ

ence

son

disc

harg

ese

tting

post

-str

oke

N=

213,

mea

nag

e=

74%

mal

e/fe

mal

e=

48/5

2%

(L)/

(R)C

VA

=42

/38,

othe

r=

20%

An

aver

age

of13

mon

ths

post

-str

oke

Dis

char

gese

tting

Age

,gen

der

Mar

itals

tatu

sS

ide/

seve

rity

ofst

roke

Com

orbi

dity

No

effe

ct–s

ide

ofst

roke

,co

mor

bidi

tyA

dver

seef

fect

–old

erag

e,fe

mal

ege

nder

,bei

ngun

mar

ried

(mal

es),

stro

kese

verit

y(f

emal

es)

Phys

Occ

up T

her

Ger

iatr

Dow

nloa

ded

from

info

rmah

ealth

care

.com

by

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ts U

nive

rsity

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For

pers

onal

use

onl

y.

Page 7: Prediction of Outcome After Stroke

Kin

g(1

996)

To

iden

tify

varia

bles

that

pred

ictQ

OL

post

-str

oke

N=

86,m

ean

age

=63

.3%

mal

e/fe

mal

e=

45/5

5%

(L)/

(R)C

VA

=35

/56,

brai

nste

mle

sion

=7%

1-3

year

spo

st-s

trok

eQ

ualit

yof

Life

Inde

xsc

ore

1to

3ye

ars

post

-str

oke

Age

Soc

ials

uppo

rtC

omor

bidi

tyD

epre

ssio

n

Adv

erse

effe

ct–y

oung

erag

e,le

ssso

cial

supp

ort,

pres

ence

ofca

rdio

vasc

ular

dise

ase,

depr

essi

on

Kon

get

al.

(199

8)T

oid

entif

yfa

ctor

sth

atpr

edic

tfun

ctio

npo

st-s

trok

e

N=

59,m

ean

age

=80

(onl

yth

ose

>75

incl

uded

)%

mal

e/fe

mal

e=

63/3

7%

(L)/

(R)C

VA

=44

/56

Pre

viou

sst

roke

excl

uded

Adm

issi

onan

ddi

scha

rge

Dis

char

gefu

nctio

n(B

arth

elIn

dex)

and

setti

ng

Adm

issi

onfu

nctio

nC

ogni

tion

Adv

erse

effe

ct–l

owad

mis

sion

func

tion,

impa

ired

cogn

ition

(fun

ctio

non

ly)

Liu

etal

.(1

997)

To

stud

yw

heth

erco

mor

bidi

typr

edic

tfu

nctio

npo

st-s

trok

e

N=

106,

mea

nag

e=

56.5

%m

ale/

fem

ale

=67

/33

%(L

)/(R

)CV

A=

56/4

4,B

ilate

ral/n

onpa

resi

sst

roke

sex

clud

ed

Rev

iew

ofad

mis

sion

/di

scha

rge

data

Dis

char

gefu

nctio

n(F

IM)

Com

orbi

dity

Adm

issi

onfu

nctio

nA

dver

seef

fect

–num

ber

and

seve

rity

ofco

mor

bidi

ties,

low

adm

issi

onfu

nctio

n

Lofg

ren

etal

.(1

998)

To

iden

tify

fact

ors

asso

ciat

edw

ithim

prov

edfu

nctio

npo

st-s

trok

e

N=

99,m

ean

age

=76

%m

ale/

fem

ale

=51

.5/4

8.5

Infa

rct=

55%

,em

bolu

s=

21%

,ha

emor

rhag

e=

15%

,oth

er=

9%,3

8%pr

evio

usst

roke

Adm

issi

onan

ddi

scha

rge

Impr

ovem

enti

nfu

nctio

n(K

atz)

and

setti

ngat

disc

harg

e

Age

,gen

der

Soc

ials

uppo

rtP

revi

ous

stro

keA

dmis

sion

func

tion

No

effe

ct–a

ge,p

revi

ous

stro

ke,

Adv

erse

effe

ct–f

emal

ege

nder

,lo

wso

cial

supp

ort,

low

adm

issi

onfu

nctio

n

Mac

cioc

chi

etal

.(19

98)

To

iden

tify

pred

icto

rsof

func

tiona

lout

com

epo

st-is

chem

icst

roke

N=

327,

mea

nag

e:m

ale

(55%

)=

69,f

emal

e(4

5%)

=72

%(L

)/(R

)CV

A=

49.5

/50.

5O

nly

thos

ew

ithis

chae

mic

stro

kein

clud

ed

7-10

days

and

3m

onth

spo

st-s

trok

e

Fun

ctio

n(B

arth

elIn

dex)

3m

onth

spo

st-s

trok

e

Age

,gen

der

Sid

eof

stro

keS

trok

ese

verit

yC

omor

bidi

tyP

revi

ous

stro

ke

No

effe

ct–g

ende

r,co

mor

bidi

tyA

dver

seef

fect

–old

erag

e,(R

)CV

A,s

trok

ese

verit

y,pr

evio

usst

roke

Nak

ayam

aet

al.(

1994

)T

ode

term

ine

whe

ther

and

how

age

influ

ence

sst

roke

outc

ome

N=

418,

mea

nag

e=

75%

mal

e/fe

mal

e=

45/5

5In

farc

t=75

%,h

aem

orrh

age

=4%

,und

efin

ed=

21%

22%

prev

ious

stro

ke

Adm

issi

on,

wee

kly

inho

spita

l,di

scha

rge

Dis

char

gefu

nctio

n(B

arth

elin

dex)

and

setti

ng

Age

Adv

erse

effe

ct–o

lder

age

(fun

ctio

non

ly)

Nie

mie

tal.

(198

8)T

oin

vest

igat

ein

fluen

ces

onQ

OL

post

-str

oke

N=

46,m

ean

age

=48

(onl

yth

ose

<65

incl

uded

)%

mal

e/fe

mal

e=

41/5

9%

(L)/

(R)C

VA

=37

/26,

othe

r=

37%

Adm

issi

on,

disc

harg

e,4

year

spo

st-s

trok

e

QO

L(s

elf-

devi

sed

ques

tionn

aire

)4

year

spo

st-s

trok

e

Age

Gen

der

Sid

eof

stro

keD

epre

ssio

n

No

effe

ct–g

ende

rA

dver

seef

fect

–old

erag

e,he

mis

pher

ical

lesi

on,d

epre

ssio

n

Phys

Occ

up T

her

Ger

iatr

Dow

nloa

ded

from

info

rmah

ealth

care

.com

by

Tuf

ts U

nive

rsity

on

11/0

4/14

For

pers

onal

use

onl

y.

Page 8: Prediction of Outcome After Stroke

TA

BLE

1(c

ontin

ued)

Aut

hor/

sG

oalo

fstu

dy(r

elat

edto

this

revi

ew)

Stu

dysa

mpl

eT

imin

gO

utco

me

mea

sure

s(r

elat

edto

this

revi

ew)

Pre

dict

ors

(rel

ated

toth

isre

view

)R

esul

ts

Ocz

kow

ski&

Bar

reca

(199

3)

To

expl

ore

the

pote

ntia

loft

heF

IMto

pred

ictp

rogn

osis

post

-str

oke

N=

113,

mea

nag

e=

66%

mal

e/fe

mal

e=

52/4

8%

(L)/

(R)C

VA

=37

/46,

bila

tera

l=17

%

Adm

issi

onan

ddi

scha

rge

Dis

char

gese

tting

Age

Gen

der

Sid

eof

stro

keA

dmis

sion

func

tion

Dep

ress

ion

No

effe

ct–g

ende

r,si

deof

stro

ke,

depr

essi

onA

dver

seef

fect

–old

erag

e,lo

wad

mis

sion

func

tion

Osb

erg

etal

.(1

988)

To

iden

tify

pred

icto

rsof

long

-ter

mou

tcom

espo

st-s

trok

e

N=

89,m

ean

age

=67

%m

ale/

fem

ale

=46

/54

Pre

viou

sst

roke

excl

uded

Rev

iew

ofho

spita

lsta

yda

ta,1

2m

onth

follo

w-u

p

Fol

low

-up

com

posi

tesc

ore

for

mor

talit

y,se

tting

&A

DL

stat

us(B

arth

elIn

dex)

Life

satis

fact

ion

Age

Gen

der

In-h

ouse

supp

orts

Out

-of-

hous

esu

ppor

tsS

ide

ofst

roke

Sev

erity

ofst

roke

Adm

issi

onfu

nctio

n

No

effe

ct–a

ge,g

ende

r,si

deof

stro

keA

dver

seef

fect

–str

oke

seve

rity,

low

adm

issi

onfu

nctio

nP

ositi

veef

fect

–in-

hous

esu

ppor

t,ou

t-of

-hou

sesu

ppor

t(lif

esa

tisfa

ctio

non

ly)

Par

ikh

etal

.(1

990)

To

stud

yth

eef

fect

ofde

pres

sion

onpo

st-s

trok

efu

nctio

n

Dep

ress

edgr

oup:

N=

25,

mea

nag

e=

56%

mal

e/fe

mal

e=

42/5

8%

(L)/

(R)C

VA

=60

/28,

brai

nste

m=

4%,b

ilate

ral=

8%N

on-d

epre

ssed

grou

p :N

=38

,m

ean

age

=61

%m

ale/

fem

ale

=66

/34

%(L

)/(R

)CV

A=

37/5

0,br

ains

tem

=8%

,bila

tera

l=5%

Inte

rvie

ww

ithin

2w

eeks

ofad

mis

sion

,fo

llow

-up

at2

year

spo

st-s

trok

e

AD

Lre

cove

ryat

2ye

ars

post

-str

oke

(Joh

nsH

opki

nsF

unct

ioni

ngIn

vent

ory)

Dia

gnos

isof

depr

essi

on(m

ajor

orm

inor

)w

hile

inho

spita

l

Adv

erse

effe

ct

Poh

jasv

aara

etal

.(19

97)

To

com

pare

post

-str

oke

func

tion

inyo

unge

ran

dol

der

patie

nts

N=

486,

age:

55-7

0(4

5%),

71-8

5(5

5%)

%m

ale/

fem

ale

=51

/49

%(L

)/(R

)CV

A=

54/4

3,ot

her

=3%

Rev

iew

ofad

mis

sion

/dis

-ch

arge

data

,3

mon

ths

follo

w-u

p

Pos

t-st

roke

func

tion

(Bar

thel

Inde

x)A

geA

dver

seef

fect

Sha

het

al.

(199

1)T

oid

entif

yva

riabl

esth

atco

rrel

ate

with

func

tiona

lrec

over

ypo

st-s

trok

e

N=

258,

mea

nag

e=

68(m

ales

),72

(fem

ales

)%

mal

e/fe

mal

e=

56/4

4T

hrom

bosi

s=

57%

,em

bolu

s=

16%

,hem

orrh

age

=16

%,

acut

eill

-def

ined

stro

ke=

12%

Pre

viou

sst

roke

excl

uded

Adm

issi

onan

ddi

scha

rge

Dis

char

gefu

nctio

n(B

arth

elIn

dex)

Age

Gen

der

Mar

itals

tatu

sS

ide

ofst

roke

Sev

erity

ofst

roke

Com

orbi

dity

No

effe

ct–c

omor

bidi

tyA

dver

seef

fect

–old

erag

e,fe

mal

ege

nder

,bei

ngm

arrie

d,(L

)CV

A,

stro

kese

verit

y

Phys

Occ

up T

her

Ger

iatr

Dow

nloa

ded

from

info

rmah

ealth

care

.com

by

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ts U

nive

rsity

on

11/0

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For

pers

onal

use

onl

y.

Page 9: Prediction of Outcome After Stroke

Sill

iman

etal

.(1

987)

To

iden

tify

the

fact

ors

that

pred

ictd

isch

arge

setti

ngpo

st-s

trok

e

N=

147,

mea

nag

e=

75%

mal

e/fe

mal

e=

56/4

4%

(L)/

(R)C

VA

=53

/42

21%

prev

ious

stro

ke

Inho

spita

land

am

ean

of11

mon

ths

post

-dis

char

ge

Dis

char

gefu

nctio

n(K

atz)

and

setti

ngA

geG

ende

rM

arita

lsta

tus

In-h

ospi

talf

unct

ion

No

effe

ct–a

ge,g

ende

r,m

arita

lst

atus

Adv

erse

affe

ct–l

owin

-hos

pita

lfu

nctio

n

Sim

etal

.(1

997)

To

dete

rmin

eou

tcom

efo

rpa

tient

sdi

scha

rged

toth

eco

mm

unity

post

-str

oke

N=

185,

mea

nag

e69

%m

ale/

fem

ale

=49

/51

22%

prev

ious

stro

ke

Rev

iew

ofad

mis

sion

/D

isch

arge

data

,12

mon

ths

post

-dis

char

ge

Dis

char

gefu

nctio

n(B

arth

elIn

dex)

and

func

tion

12m

onth

spo

st-s

trok

eD

isch

arge

setti

ng

Age

Adv

erse

effe

ct–o

lder

age

Sin

yor

etal

.(1

986)

To

exam

ine

the

impa

ctof

post

-str

oke

depr

essi

onon

reha

bilit

atio

nou

tcom

e

N=

64,m

ean

age

=67

%m

ale/

fem

ale

=61

/39

%(L

)/(R

)CV

A=

45/5

5P

revi

ous

stro

keex

clud

ed

Adm

issi

onan

ddi

scha

rge,

6w

eeks

post

disc

harg

e

Dis

char

gefu

nctio

n(2

0ite

ms

from

the

Pat

ient

Eva

luat

ion

Con

fere

nce

Sys

tem

)

Dep

ress

ion

Adv

erse

effe

ct–d

epre

ssio

n

Tau

bet

al.

(199

4)T

oid

entif

ypr

edic

tors

offu

nctio

n1

year

afte

rfir

st-t

ime

stro

kein

patie

nts

<75

year

s

N=

639,

med

ian

age

=67

%m

ale/

fem

ale

=56

/44

Inho

spita

land

3an

d12

mon

ths

post

-str

oke

Fol

low

-up

func

tion

(Bar

thel

inde

x)A

geG

ende

rLi

ving

situ

atio

nS

trok

ese

verit

y

No

effe

ct–a

ge,g

ende

r,liv

ing

situ

atio

nA

dver

seef

fect

–str

oke

seve

rity

Wad

eet

al.

(198

6)T

oid

entif

ypr

edic

tors

offu

nctio

nalr

ecov

ery

post

-str

oke

N=

976,

mea

nag

e=

72%

mal

e/fe

mal

e=

47/5

3%

(L)/

(R)C

VA

=46

/40,

othe

r=

12%

Adm

issi

on,

3w

eeks

and

6m

onth

saf

ter

stro

ke

Fun

ctio

n(B

arth

elIn

dex)

and

setti

ng6

mon

ths

post

-str

oke

Age

Gen

der

Sid

eof

stro

ke

No

effe

ct–s

ide

ofst

roke

Adv

erse

effe

ct–o

lder

age,

fem

ale

gend

er(a

ssoc

iatio

nsfo

und

betw

een

age

and

gend

er)

Wee

net

al.

(199

6)T

oid

entif

ypr

edic

tive

ofpo

st-s

trok

eou

tcom

e

N=

376,

mea

nag

e=

73%

mal

e/fe

mal

e=

45/5

5%

(L)/

(R)C

VA

=41

/37,

othe

r=

22%

With

in2-

3da

ysof

adm

issi

onan

dat

disc

harg

e

Dis

char

gefu

nctio

n(F

IM)

and

setti

ngA

geA

bsen

ceof

aca

regi

ver

Sid

eof

stro

keS

trok

ese

verit

yC

omor

bidi

tyP

revi

ous

stro

keA

dmis

sion

func

tion

No

effe

ct–p

revi

ous

stro

keA

dver

seef

fect

–old

erag

e,ab

senc

eof

aca

regi

ver

(set

ting

only

),bi

late

rall

esio

nsan

d(R

)CV

A(f

unct

ion

only

),st

roke

seve

rity,

cum

ulat

ive

com

orbi

dity

(fun

ctio

non

ly),

low

adm

issi

onfu

nctio

n

Wils

onet

al.

(199

1)T

oid

entif

yfa

ctor

sth

atpr

edic

tdis

char

gese

tting

post

-str

oke

N=

282,

mea

nag

e=

69%

mal

e/fe

mal

e=

48/5

2%

(L)/

(R)C

VA

“app

roxi

mat

ely

equa

l”

Adm

issi

onan

ddi

scha

rge

Dis

char

gese

tting

Age

,gen

der

Mar

itals

tatu

sS

ide

ofst

roke

Adm

issi

onfu

nctio

n

No

effe

ct–a

ge,g

ende

r,m

arita

lst

atus

,sid

eof

stro

keA

dver

seef

fect

–low

adm

issi

onfu

nctio

n

Phys

Occ

up T

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y.

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Page 11: Prediction of Outcome After Stroke

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Page 12: Prediction of Outcome After Stroke

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Page 13: Prediction of Outcome After Stroke

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Page 14: Prediction of Outcome After Stroke

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Page 15: Prediction of Outcome After Stroke

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Page 16: Prediction of Outcome After Stroke

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Page 17: Prediction of Outcome After Stroke

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Page 18: Prediction of Outcome After Stroke

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Page 19: Prediction of Outcome After Stroke

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Page 20: Prediction of Outcome After Stroke

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