Ralph J. Altiere, Dean November 14, 2012 Skaggs School of Pharmacy and Pharmaceutical Sciences

2012

Roger Kovacs, Jr. “RJ” 1984 - 2012 RJ was a P2 student and a pharmacy intern at the north Boulder Safeway when he passed away in June 2012.

Carol Sue Stehley 1940 – 2012 Carol’s mother, Pearl Stehley, was an alumna and a loyal supporter of our school. Upon her mother’s death, Carol remained a supporter of the school, most recently donating funds for our new building, specifically for the room that bears her name and houses the NMR equipment.

George Masunaga 1914 - 2011 George Yoshito Masunaga was an alumnus of our school (1941) and a long time supporter. George worked as a chemist with the Denver and Rio Grande Railroad, as chief civilian pharmacist at Lowry Air Force Base, and later operated Walgreens stores in Denver and Adams County with his two brothers. He then opened and operated his own pharmacy, Swansea Drug Store, for many years. His family and friends generously provided donations to fund scholarships in his name that were awarded in 2011.

In memoriam

Janella Lyn Olinger 1963-2012 Janella was a hospital pharmacist and worked in the pharmaceutical industry most recently at Allergan. She was a faculty member serving as an instructor and preceptor in our NTPD program and served that program in various other capacities over a number of years. Tony Everett Jones 1920 – 2012 Tony Jones earned a PhD degree in Pharmaceutical Chemistry from the school in 1957 and was a long-time member of our faculty serving 33 years from 1954-1987. Tony was a research scientist for his entire career that continued until shortly before his death. He was creator and co-editor of the American Drug Index. Tony is perhaps best recognized for the creation and development of numerous well-known products including Blistex and Clearasil among many others. He received the University of Colorado School of Pharmacy Distinguished Coloradan Award in 1991. Al Malkinson 1941-2012 Scientist, scholar, educator, mentor, writer, patron of the arts, especially cinema, and a warm and caring person. Upon graduation from Johns Hopkins University with a PhD in biochemistry, Al and his wife, Lynn, served for two years in the Peace Corps in Kenya. Al served on our faculty for 34 years, joining the school in 1978. He conducted lung cancer research throughout his career, published hundreds of papers and taught in both our pharmacy and graduate PhD programs through the spring 2012 semester, just months before his death in August. In 2004, he was awarded the Shell Prize for outstanding research and teaching.

In memoriam Ruthanne Rockey Ramsey - 2012 Ruthanne died on July 13, 2012. Dr. Ramsey graduated with honors from Ohio Northern in 1976 and received her Doctorate of Pharmacy from the University of Texas-Austin in 1984. She graduated from the University of Utah Gerontology program in 1985, completing a Post-Doctorate Residency in Geriatric Clinical Pharmacy. During an outstanding career in teaching Pharmacy doctorate students, she received numerous teaching awards, including the President's Excellence in Teaching from the University of Colorado.

Outline

2012 Operations

Demographics

Highlights in our mission areas

Looking Forward

Operations2012

-

5,000,000

10,000,000

15,000,000

20,000,000

25,000,000

30,000,000

35,000,000

40,000,000

45,000,000

50,000,000

Revenue Sources1990-2012

Other Grants Clinical Contracts Tuition & Fees State Appropriations

0 2 4 6 8 10 12 14 16

Endowment

F & A

State Funds

Auxiliaries

Tuition & Fees

Grants/Contracts

Millions

Revenue Sources

TOTAL REVENUES 2010/11 $40,744,983 2011/12 $42,604,559

2010/11

2011/12

0 2 4 6 8 10 12

Other Expenses

Compensation

Millions

Unrestricted Fund Expenditures

2010/11 $12,811,399 2011/12 $13,367,271

2010/11

2011/12

0 1 2 3 4 5 6

Sponsored Projects,Clinical Contracts,

Departments

Unrestricted

Millions

Faculty Salary Sources2012

2011/12 $8,657,310

Demographics

Students* 1043 Residents** 11 Post-doctoral fellows 16 Faculty Regular Faculty 58 Research 17 Clinical Instructors 11 Preceptors 905 Instructors 8 Adjunct professors 2 Distance Degree Program Instructors 95 Staff Administrative 37 Research 33 TOTAL *Students 2236 Grad students: total 56; PS 27; PS POR 3; Tox 26 PharmD: 648 NTPD: 339 **Residents: total 11; PGY1 – 4 at UCH; PGY1 – 1 at KS; PGY2 – 6 – Oncology, Family Med, Amb Care, Infectious Diseases, Critical Care

Demographics2012

…at a glance

2012 2016

Female/Male CO/not CO PCAT composite Avg GPA Degrees earned

84/73 84/73 72 3.31 139

Nationwide applications: 84, 593 (drop from 85,717 in 2009/10) Resident applicants: increase from 168 (2011) to 175 (2012) Resident admits: increase 74 (2011) to 84 (2012)

White 64.8% African American 3.8% Hispanic 10.1% Asian/Pacific Islander 18.2% Native American 1.3%

Ethnicity Class 2016

Class 2016

Faculty & Staff

Faculty Recruitments/Hires DOCP New hires: Scott Mueller-Aug ‘11, Steve Smith-Aug ‘11, Katy Trinkley-Oct ’11, Sarah Carson-Sept ’12 Current recruitments: two senior clinical instructors in ambulatory care for Salud Clinics DOPS New hires: Erica Pierce-Jan’12, Melanie Joy-Aug ‘12, Molly Huntsman-Sept ’12 Currently four searches: Med Chem; Metabolomics/Systems Biology; Drug Delivery/Nanotechnology; Molecular Biophysics Faculty Promotions and Tenure 2011: Tom Anchordoquy – Professor; Joseph Saseen – Vice Chair DOCP; Catherine Jarvis – Associate Dean 2012: David Thompson – Associate Dean; John Carpenter – Director of Business Development; Anne Libby – Tenure

Faculty & Staff New staff hires from January 2011 to current

Three staff positions in DOPS and grants accounting

Four staff positions in NTPD and CE

Four staff positions combined in Experiential Programs and Office of Student Services

Mission areas

Education

Research

Clinical/Service

Education programs

PharmD degree program

NTPD degree program for practicing pharmacists

CE program

PhD Pharmaceutical Sciences, including POR

PhD Toxicology

Residency programs – PGY1 and PGY2

Postdoctoral programs

Education highlights

PharmD Program Mission Provide educational activities that prepare students to fully participate in team-based care delivery models and performance-based payment for services Curriculum Renewal Continuous improvement and advancement in current curriculum Renewed curriculum initiated 2012-13 Interprofessional Education Honors Program Revitalized Honors Program Currently 28 students in the program

Education highlights

Rural education opportunities

Students placed in 231 rural pharmacy locations in Colorado Students counseled 15,463 patients and answered over 6,400 drug information questions Disease state management clinics – 1,758 one-on-one visits of one hour or more between patients and students IPE in rural settings – 738 pairings that reached over 22,000 patients NTPD Program

Second largest program of its kind in US Robust enrollment – 339 currently enrolled; 63 admits 2012 Teleconferencing for active learning courses CE programs Science and Practice CE Program – Translating Research to Pharmacy Practice Residency Programs

PGY1 – 4 at UCH; 1 at King Soopers PGY2 – 6 in Oncology, Family Med, Ambulatory Care, Infectious Diseases, Critical Care

Professional Student highlights

Student Ambassadors Program – recruiting through community outreach, promoting the profession 2011 ASHP Student Leadership Award – Heather Woodward 2011 Outstanding Community Service Award AMC – NCPA SNPhA Awarded grant funds for community health fairs First place in business plan competition at SNPhA National Meeting Awarded host for SNPhA Regional Meeting in 2013 (2nd time) NCPA Top 10 Chapter of the Year Health and Wellness Challenge winner Legislative Challenge first runner up NCPA business plan national competition – top 10 finish (5th place unofficially) 32 Residency matches 2012

NAPLEX and MPJE Results

NAPLEX

MPJE

2012 98.53 (97.19) 95.67 (93.94)

2011 97.22 (96.57) 100.00 (96.05)

2010 100.00 (95.31) 98.56 (95.50) 2009 98.13 (97.50) 98.04 (94.30) 2008 98.35 (97.44) 97.58 (91.16)

% Pass Rate CU (National)*

*First time test takers May-Aug test window

Ranking: top 20%

Research

Leading edge research programs Areas of research Cancer Neuroscience Pharmaceutical Biotechnology Biomedical Nanotechnology Structural Biology Immunology Toxicology Medicinal Chemistry Clinical Translational Pharmacogenomics HIV/AIDS POR Clinical oncology, diabetes, critical care, epilepsy, MS

Research standings

• No. 1 vs. 8 basic sciences departments in SOM • No. 5 vs. all 27 SOM departments

Research Expenditures $13.6M for 2011-12

• No. 3 among U.S. pharmacy schools

Individual NIH awards per PhD faculty

• No. 14 among U.S. pharmacy schools

NIH funding

• No. 2 among U.S. pharmacy schools

PharmD faculty with NIH funding

Total Awards $9,221,674

NIH $5,970,874

State $968,853

Corporate Contracts $465,933

Non-profit $741,651

Fed Other $1,074,363

RESEARCH 2012 Calendar year – 10 months only

Research standings

Agarwal NIH NEI $3,730,021

Kompella NIH NEI $499,000

Kompella FDA $494,634

Vasiliou NIH NEI $424,979

Patel The Michael J. Fox Foundation $415,151

Research standings

2012 new awards over 400K

Research highlights

Vaccine thermostabilization novel technology developed by Drs. John Carpenter (DOPS), Ted Randolph (UCB), Amber Clausi (UCB) and license agreement with Soligenix, Inc. Barofold, a company founded by Dr. John Carpenter, licensed its Pressure Enabled Protein Manufacturing (PreEMT™) Technology developed by Drs. John Carpenter and Ted Randolph for stabilizing protein therapeutics to Boehringer Ingelheim for development of biopharmaceutical products in its Vienna, Austria facility NU100, a recombinant human interferon beta-1b therapeutic produced by Barofold, Inc., for treatment of relapsing remitting multiple sclerosis, is in Phase 3 clinical trials by Nuron Biotech, Inc. A colon cancer biomarker and potential therapeutic target identified by Dr. Vasilis Vasiliou Development of AEOL 10150 as a nerve gas countermeasure by Dr. Manisha Patel

Research highlights

Grape seed extract and resveratrol selectively kill head and neck cancer cells in studies conducted by Dr. Rajesh Agarwal Landmark research and paper published November 2012 on binding of dystrophin to F-actin, a critical mechanism in muscular dystrophy by Dr. Krishna Mallela 2012 Drug Delivery Symposium in honor of Dr. H.L. Vincent Lee by Dr. Uday Kompella at CU SSPPS 2012 ARVO (Association for Research in Vision and Ophthalmology) Eye Research Drug and Gene Delivery Conference organized and chaired by Dr. Uday Kompella at the CU SSPPS 2012 Anschutz Medical Campus Graduate Mentoring Award to Dr. Uday Kompella Critical Care PRN Research Award to Dr. Doug Fish

Research highlights

DOPS graduate students hosted AMC research symposium in 2012 Awards 2012 Rinku Baid received the National Biotechnology Conference Biotechnology Graduate Student Symposium Award, sponsored by Eli Lily and Company Rajendra Kadam received the AAPS Graduate Student Symposium Award in Pharmacokinetics, Pharmacodynamics, Drug Metabolism, and Clinical Pharmacology and Translational Research, sponsored by Eli Lily and Company Jiban Jyoti Panda received the AAPS Graduate Student Symposium in Formulation Design and Development, sponsored by Pfizer, Inc. Puneet Tyagi received the AAPS Graduate Student Symposium Award in Biotechnology, sponsored by Pfizer, Inc. Arun Upadhyay received the AAPS Innovations in Nanotechnology Award, sponsored by Hospira, Inc.

Skaggs Scholars

The Skaggs Scholars Program, centered at the University of Colorado and funded by a generous grant from The ALSAM Foundation, is designed to stimulate collaborative research among the Skaggs institutions; University of Arizona, University of California San Diego, Idaho State University, The University of Montana, The Scripps Research Institute/The Skaggs Institute for Chemical Biology, University of Utah.

Cynthia Ju, PhD Anne Libby, PhD Krishna Mallela, PhD Manisha Patel, PhD Vasilis Vasiliou, PhD

Clinical/Service highlights

Comprehensive Medication Management, Formulary and Outcomes Research Services University of Colorado Health and Wellness Trust New initiative in 2011-2012 – roll out of program; modest number of patients 2012-2013 – leading the collaboration with Cigna to optimize medication use across all plan beneficiaries Colorado Access Seniors Clinic, AF Williams Family Practice and Internal Medicine in AOP and Lowry Clinic State Initiatives DUR (Drug Utilization Review) Contract with Colorado Medicaid Program Review medication use and make recommendations for improving quality of care and reducing costs Initial review of PPI use resulted in $2M savings to program Rural Diabetes Education Program Grant from CDPHE Train pharmacists in rural Colorado to provide Diabetes Self-Management Education (DSME) University Collaborations Flu shot clinics on CU campuses Collaborations with College of Nursing Clinical Pharmacy Services at Sheridan Clinic Informatics training grant Training health care professionals in use of health information technology

Clinical/Service highlights

Elizabeth D. Gee Memorial Lectureship Award received by Dr. Laura Borgelt (2011) Recognized as a PSPC champion – Dr. Sarah Anderson (2011) Denver Health Employee of the month – Dr. Joel Marrs (July 2011) Fellow of the American Society of Health-System Pharmacists (FASHP) – Dr. Joseph Saseen USP representative appointed by American Heart Association – Dr. Robert Page Selected section editor for Cardiology for AACP Pharmacotherapy Self Assessment Program – Dr. Robert Page Elected to American Geriatrics Society Board of Directors – Dr. Sunny Linnebur (2012) Dean Ralph Altiere elected president of FIP Academic Section (2011) Colorado Prescription Drug Abuse Program hosted by our school (Dr. Rob Valuck) with Governor Hickenlooper and R. Gil Kerlikoske, Director of the Office of National Drug Control Policy Expert commentary and service for news channels and publications by clinical faculty members

Fund raising highlights

The ALSAM Foundation $1M initial gift to start Skaggs Scholars Program Additional $1M commitment to continue program Annibel Gardner Trust $100K building fund Centennial Scholarship Fund $71K 100% participation by faculty; 85% participation by staff Gene McMahan $65K to support the Teresa McMahan Shulkin Memorial Scholarship

Friends, alumni, donors, local dignitaries, university officials, politicians and the Skaggs family were present August 29, 2011 to dedicate the new Pharmacy and Pharmaceutical Sciences building and officially change the name of the school to the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences.

Building dedication – 100th Anniversary

100th Anniversary

Skaggs School of Pharmacy and Pharmaceutical Sciences

DOPS hosts two scientific symposia attended by hundreds in the new seminar room. Speaker - Christopher P. Austin, M.D., new director of NCATS in NIH

Centennial Scholarships: one student from each PharmD class, one PhD student, one NTPD student

Convocations Steven C. Anderson, IOM, CAE President and Chief Executive Officer National Association of Chain Drug Stores Michael Maddux, PharmD, FCCP Executive Director American College of Clinical Pharmacy Henri Manasse, Jr., PhD Executive Vice President & Chief Executive Officer Emeritus American Society of Health-System Pharmacists B. Douglas Hoey, Pharmacist, MBA Chief Executive Officer National Community Pharmacist Association Thomas Menighan, BSPharm, MBA, ScD Executive Vice President & Chief Executive Officer American Pharmacists Association

Norman Fenn P3, Kelsey Melander P2, Danielle Smidt P4, Molly Derry PhD candidate, Michael Thompson NTPD student (not shown)

Acknowledgment to The ALSAM Foundation,

L.S. and Aline Skaggs

Ronny Cutshall Susie Skaggs Balukoff

Msgr. J. Terrence Fitzgerald

Arnold LaGuardia Claudia Skaggs Lutrell

Don L. Skaggs Mark S. Skaggs

L.S. Skaggs Biomedical Symposium

L.S. Skaggs Symposium participants

100th Anniversary

Special guest Tom Cech, PhD Nobel Laureate 1989 Chemistry

Education initiatives Curriculum renewal roll out over next three years Education technology recruitment iPharmD; International Affairs Coordinator; ACPE review FIP AcPS programs at FIP Congress Global Conference on Pharmacy Education targeted for 2015 IPSF Egypt, Turkey, others

Research Associate Dean for Research Faculty recruitments Foster interdisciplinary research CCTSI Clinical translational research Clinical research Drug Discovery Program with AMC and Biofrontiers

Looking forward

Clinical CU Health and Wellness Trust – expand CMM and other services Integration with University of Colorado Health System Capitalize on emerging health care models Advance practice Engagement with PCMHs, ACOs Pharmacist Managed Medicare Outreach in Primary Care Establishment of Clinical Pharmacy Services in Colorado Community Health Centers to Optimize Medication Management and Patient Outcomes

Looking forward