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Volume 19 Number 4 October-December 2018 PHILIPPINE COLLEGE OF CHEST PHYSICIANS RESEARCH AGENDA 2019-2023

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• PCCP Position Statement on E- Cigarettes

• MDMA-induced pneumothorax

Volume 19 Number 4

October-December 2018

PHILIPPINE COLLEGE OF

CHEST PHYSICIANS

RESEARCH AGENDA

2019-2023

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PHILIPPINE COLLEGE OF CHEST PHYSICIANS OFFICERS 2018-2019

PHILIPPINE JOURNAL OF CHEST DISEASESAN OFFICIAL PUBLICATION OF THE

PHILIPPINE COLLEGE OF CHEST PHYSICIANS

Lenora C. Fernandez, MD, FPCCP

President

Malbar G. Ferrer, MD, FPCCP

Vice President

Ivan N. Villespin, MD, FPCCP

Secretary

Gregorio P. Ocampo, MD, FPCCP

Treasurer

Imelda M. Mateo, MD, FPCCP

Eileen G. Aniceto, MD, FPCCP

Ma. Janeth T. Samson, MD, FPCCP

Jubert P. Benedicto, MD, FPCCP

Virginia S. de los Reyes, MD, FPCCP

Board Members

Charles Y. Yu, MD, FPCCP

Immediate Past President

Editor-in-Chief

Evelyn Victoria E. Reside, MD, FPCCP

Managing Editor

Camilo C. Roa, Jr., MD, FPCCP

Copy Editor

Blesilda O. Adlaon

Editorial Assistant

Ivan Noel G. Olegario, MD, MDC

The opinions and data expressed in the Philippine Journal of Chest Diseases (PJCD) are those of the individual authors. They are not

attributable to the editors or editorial board of the PJCD and should not be regarded as the official stand of/or endorsement by the

Philippine College of Chest Physicians. References may be made in the articles regarding drug usage, which may not be included in the

current prescribing information. The reader is, thus, urged to check the full prescribing information of drugs. No part of the PJCD may be

reproduced without the written permission of the publisher.

Address all communication and manuscripts for publication to the following: The Editor, Philippine Journal of Chest Diseases, 84-A Malakas

St., Pinyahan, Quezon City. Email: [email protected]. Phone: (+632) 924 9204.

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The Philippine Journal of Chest Diseases

publishes scientific papers in the field of

pulmonary medicine. These papers may be in the

form of collective and current reviews (state of the

art, meta-analyses), original investigations, case

reports, editorials or letters to the editor. All

manuscripts must be submitted electronically to

[email protected]. Manuscripts should be

single spaced and left-justified, including

references. Use 10-point type, approximately 1-

inch margins, and format for 8 ½ x 11 paper. The

editorial staff requires files that can be opened and

manipulated in Word 2004-2009, PowerPoint or

Excel.

Accepted manuscripts become the property of the

Philippine College of Chest Physicians and are

published with the understanding that they are not

for publication elsewhere without approval.

These manuscripts are subject to editorial

modification.

Generally, write using the first person, active

voice; for example, “We analyzed data,” not

“Data were analyzed.” The Abstract

and acknowledgments or disclaimers are the

exceptions to this guideline, and should be written

in the third person, active voice; “The authors

analyzed,” “The authors wish to thank.”

Supply a title page as the first page of the

manuscript with the following information:

1. The manuscript’s full title which should

provide sufficient information regarding the

contents of the manuscript.

2. All authors should provide their complete

names, professional titles, and institutional

affiliations. Include an author byline that lists

all authors’ full names and academic degrees

above a Masters; for example, “Juana Cruz,

MD, PhD, and Juan Ramos, MD”. Also

include sentence-style bios for each author

than list position(s) or title(s) and institutional

affiliation(s); for example, “Dr. Cruz is

assistant professor, Section of Pulmonary

Medicine, Department of Internal Medicine,

State University College of Medicine”.

3. Contact information (address and email

address, plus telephone and/or fax) for the

corresponding author.

INSTRUCTIONS TO AUTHORS

4. Disclosure of funding received for this work

from any organization or company.

5. State if the paper has been presented in any

convention and whether any awards have

been conferred on the paper.

Abstract. The abstract should not be longer than

250 words. It should contain a summary of what

was done in the study, including objectives, study

design, important results and conclusions. Only

findings restricted to the study should be

mentioned in the abstract. For research reports

only, abstracts must be in the structured form of

four paragraphs, with headings Purpose,

Methods, Results, and Conclusions; and must

include the year of the study. The authors should

also provide three key words under which the

article can be indexed.

Headings

For all manuscripts. Use main headings and

short subheadings as needed. Do not create a

heading at the very top of the manuscript (e.g.,

“Introduction”), since layout constraints make

such headings unworkable. Text should be set in

Times New Roman font, 10 point in size, and

single-spaced. The main heading of the online-

only text should be in 12 point and boldface;

subheadings should be in 10-point and boldface.

If subheadings are used, two or more such

headings must be used, as in outline style.

For research reports. Structure the body of the

manuscript using the headings Introduction,

Methods, Results, and Conclusions. At least a full

paragraph of text must precede the Introduction

heading, for layout reasons.

For articles. Create headings that are substantive

and interesting and that will give readers a sense

of the article’s organization. Make headings as

short as is feasible. At least a full paragraph of

text must precede the initial heading, for layout

reasons.

Text. Formal scientific or technical style shall be

followed in writing the manuscripts. All

abbreviations should be spelled out when used

for the first time. For standard terminology,

such as chronic obstructive pulmonary disease

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(COPD) or forced vital capacity (FVC), only

standard abbreviations should be used. Information

or data that is best described in tables should be

presented as such. Tables which duplicate

information provided in the text shall be removed.

Generic names of drugs shall be used except in

instances where trade names are vital, such as in

clinical trials.

Tables and Figures. Only tables cited in the text

should be included. All tables should be called out

in the text and shall be numbered in ascending

order depending on the sequence they were

referred to in the text. A different order for tables

and figures is to be used. Symbols are * † ‡ § ¶.

A single table or figure with the appropriate labels

should be printed on a single page. The text and

data in online tables should be Arial font, 10 point

in size, and single-spaced. The table title should be

set in Arial font 12 point, and bold. Headings

within tables should be set in 10 point bold.

Explanatory notes or legends should be written

at bottom of the table or figure. Table titles should

make the table sufficiently understandable

independent of the manuscript. Typically, include

type of data, number and type of respondents, place

of study, year of study. Titles should be placed

directly above the table, not in a data cell. Columns

should be clearly labeled, including unit of

measure.

Footnotes: If information is needed to make the

table understandable that won’t easily fit into the

table title or data cells, create one or more

footnotes. Table footnotes should be set in 8 point

and single-spaced. Place footnotes at the bottom of

the table, not in a data cell. All abbreviations

should also be explained.

Figures. Only figures (or pictures) cited in the text

should be included. All figures should be called out

in the text and shall be numbered in ascending

order depending on the sequence they were

referred to in the text. A different order for tables

and figures is to be used.

Figures are acceptable as Excel, PowerPoint

or Word 2004-2009 files. All files supplied must be

“live” figures that can be opened and formatted.

PDFs and JPGs are not accepted. Figures should

be two-dimensional; black-and-white or

grayscale; and without gridlines or background

shading. X and Y axes, if present, must be

labeled.

Figure legends should make the figure

sufficiently understandable independent of the

manuscript. Legends should be placed on the last

page in the manuscript. All figures should be

separated from the text file, yet bundled into a

common file, if possible, with individual figures

separated by page breaks.

The editorial staff reserves the right to determine

whether the graphical instruments are appropriate

for the information being imparted and modify or

request modification/s for inappropriate

illustrations. The editorial staff reserves the right

to generate illustrations compatible with the

professional standards of the journal.

References. Authors are responsible for the

accuracy and completeness of their references and

for correct text citations. All references should be

identified at the appropriate parts of the text using

Arabic numerals enclosed in parentheses. All

references should then be typed double-spaced at

the end of the manuscript and numbered

according to the order they were cited in the text.

Journal references should include the names of all

the authors and inclusive page numbers.

Abbreviations of names of journals should

conform to those used in the Index Medicus.

For world wide web citations, follow the

following format: <author’s name> <title of

document> <<URL>> <date of document>

(accessed <date accessed>). You may break

URLS across lines, but if possible, arrange for

breaks to occur only at punctuation separators

(but not on hyphens, and don’t ever add hyphens).

Samples of the style to be followed in the listing

references are enumerated below:

JOURNAL ARTICLE: Tanchuco JQ, Young J.

Normal standards for spirometric tests in Filipino

children. Chest Dis J 1989. 16:93-100.

INSTRUCTIONS TO AUTHORS

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BOOK: Kelley MA, Fishman AP. Exercise

Testing. In: Pulmonary Diseases. 2 edition.

Fishman AP, (ed.). McGraw-Hill Book Co.; 1989.

pp.2525-2532.

WORLD WIDE WEB: Horton M, Adams R.

Standard for interchange of USENET messages

Request for comment s 1036, Network Working

Group. <ftp://ftp.demon.co.uk/pub/doc/rfc/rfc1036.

txt> Dec.1987 (Accessed 19 June 1995)

Personal communications, unpublished data or

manuscripts in preparation should not be used as

numbered reference. Instead, these may be cited in

parentheses or as a footnote on the page where they

are mentioned. Authors assume responsibility for

verifying the accuracy of their cited reference.

Advertisements. All requests for rates should be

add-ressed to: The Business Manager, Philippine

Journal of Chest Diseases, PCCP Secretariat, 84-A

Malakas St., Brgy. Pinyahan, Diliman, Quezon

City (Telephone No. 924-9204 and Fax No. 924-

0144). The journal also accepts announcements

from institutions or professional

INSTRUCTIONS TO AUTHORS

invitations to forthcoming symposia or convention

for publication at minimal cost depending on

available space.

Reprints. Requests for additional reprints of

individual articles should be addressed to: The

Editor-In-Chief, Philippine Journal of Chest

Diseases, PCCP Secretariat, 84-A Malakas St.,

Brgy. Pinyahan, Diliman, Quezon City (Telephone

No. 924-9204 and Fax No. 924-0144). Author/s of

each manuscript are entitled to 25 copies of the

article. These shall be sent to the major author.

Requests for reprints should be addressed to the

senior author. Reprints of entire issues may be

provided at cost, depending on availability of

copies.

Subscriptions. All requests for subscriptions should

be addressed to: The Business Manager, Philippine

Journal of Chest Diseases, PCCP Secretariat, 84-A

Malakas St., Brgy. Pinyahan, Diliman, Quezon City

(Telephone No. 9249204 and Fax No. 924-0144. E-

mail address [email protected]. One issue

(P120.00). Back issues (depending on availability

P120.00).

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Editorial: The PCCP, the PJCD and the pulmonary researcher

Philippine College of Chest Physicians Research Agenda Setting

2019-2023

Appendix I: Review of local researches

Appendix II. Revised guidelines on research grant applications

OCTOBER-DECEMBER 2018 VOLUME 19 NUMBER 4

1

3

30

43

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Philipp J Chest Dis 201811

EDITORIAL

The PCCP, the PJCD and the

pulmonary researcher

Evelyn Victoria E. Reside, MD, FPCCP

Editor-in-Chief

As the year comes to a close, it is but

fitting to end with a clear understanding of

what knowledge gaps there are and what

needs to be done to fill them, with regards to

the realm of pulmonary medicine in the

Philippines.

Indeed, with more than seven

thousand islands, and more than 100 million

people, in an environment akin to a cultural

hotpot from north to south, to generate

research in a small corner of the country, and

to claim its results as attributable to the

whole, will never be fair nor accurate for the

general population. Although there are data

from some small studies which hold

significant value, what is more evident is

that the country needs data generated on a

larger scale, which is perpetually a challenge

considering the architecture of the country,

and how most pulmonary specialists are

distributed, with practice primarily in

abundance in the urbanized areas. Moreover,

there is also the fact that pulmonary training

programs are not as common as other internal

medicine subspecialties, so that the number of

those who are compelled to conduct

pulmonary research become even less.

Nevertheless, there is hope for the

pulmonary researcher. This issue of the PJCD

highlights the current state of published local

knowledge contributing to the landscape of

useful medical information. However, as

pulmonary medicine is dynamic, so should

research be dynamic as well. The mind must

“If we knew what it was we were doing, it would not be called research, would it?”

- Albert Einstein

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Vol. 19 | Issue 03 | September 2018 22Vol. 18 | Issue 02 | June 2017

always be curious for there is an overflow

of patient resources continuously avail-

able, and there is always a public health

concern associated with the lungs, such as

smoking and pulmonary infections. But this

issue simplifies matters for the prospective

researcher and curious pulmonologist; it

already identifies the gaps and the

questions, and all that needs to be done is to

answer them. Such is the necessity and the

urgency of national data: the PCCP has

already set the stage, it is now up to the

College to respond.

And to respond will not only be to

heed the call of the PCCP, but will also be

to respond to the needs of our fellow

Filipinos.

“Research is what I’m doing when I

don’t know what I’m doing.”

- Wernher von Braun

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Philipp J Chest Dis 20183

PHILIPPINE COLLEGE OF CHEST PHYSICIANS

RESEARCH AGENDA 2019-2023

Leadership Group:

Dr. Virginia S. de los Reyes

Dr. Lenora Fernandez

Technical Working Group:

Dr. Luisito Idolor

Dr. Jubert Benedicto

Dr. Aileen David-Wang

Dr. Raiza Visita

Dr. Miriam Lalas

Participants

PCCP Board of Directors:

Dr. Lenora Fernandez

Dr. Ivan Villespin

Dr. Jubert Benedicto

Dr. Eileen Aniceto

Dr. Virginia de los Reyes

Technical Adviser:

Professor Cynthia Cordero

• MS Public Health, University of the Philippines

• Master of Medical Statistics, University of Newcastle, Australia

• Professor, Department of Clinical Epidemiology, UP College of Medicine

• Project Leader, PNHRS Initiative to Develop Guidelines for Health

Research Prioritization

• Member, Research Agenda Committee, Philippine National Health

Research System (1990-2017)

Research Agenda Setting Workshop, September 1, 2018

AVR Lung Center of the Philippines

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Vol. 19 | Issue 03 | September 2018 4

Cluster on Chronic Airway Diseases:

Dr. Gene Louie Philip Ambrocio

Dr. Aileen David-Wang

Dr. Chona De Vera

Dr. Glynna Ong-Cabrera

Dr. Tim Trinidad

Dr. Eileen Aniceto

Cluster on Critical Care/Vascular/Sleep:

Dr. Ma. Paz Mateo

Dr. Christopher Cortes

Dr. Rodolfo Dizon Jr.

Dr. Geraldine Garcia

Dr. Patrick Gerard Moral

Dr. Russel Omena

Cluster on ILD/OLD/Lung malignancy/Smoking

Dr. Shane Ceniza-Boiser

Dr. Dina Diaz

Dr. Melissa Lim-Bagay

Dr. Ma. Encarnita Limpin

Dr. Kriselda Tan

Dr. R. Tipones

Cluster on Pulmonary Infections

Dr. William Del Poso

Dr. Jesus Egargo

Dr. Jose Herson Morfe

Dr. Rodolfo Pagcatipunan Jr.

Dr. Jubert Benedicto

Dr. Luisito Idolor

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Philipp J Chest Dis 20185

Cluster on Education & Training

Dr. Guilvic Tirso Aspiras

Dr. Bernice Ong-Dela Cruz

Dr. Christine Agatha Untalan

Facilitators:

Professor Cynthia Cordero

Dr. Virginia de los Reyes

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Vol. 19 | Issue 03 | September 2018

INTRODUCTION

The Philippine College of Chest Physicians (PCCP) in pursuing its mission and vision,

is committed to supporting relevant and quality research to improve our country’s

health. As the leading expert in pulmonary health, PCCP envisions itself to be the

catalyst for meaningful, systematic and relevant research on lung diseases. However,

given its limited resources and the inequity in global research funding, there is a need

to channel these limited resources to answer the most important research questions

with the greatest impact and relevance.

On July 2, 2017, during the PCCP strategic planning workshop, it was decided to

reinforce the research capability of the College through the following action plans: 1.)

To revisit the PCCP research priorities and align with Department of Health (DOH)

priorities , 2.) To increase PCCP identified research involving the different Councils,

Chapters, training institutions in collaborative research, and 3.) To create a network of

funding agencies for the identified priority research topics.

To revisit the PCCP research priorities, the PCCP spearheaded and supported a

research agenda setting initiative. Through this activity which culminated with a

workshop on September 1, 2018., it was hoped that PCCP could better prioritize and

integrate the College’s research activities. PCCP emphasized inclusiveness by

engaging the PCCP’s Councils, Chapters and training institutions in crafting a

research agenda. PCCP recognized national frameworks particularly the Philippine

National Health Research Agenda to guide the agenda setting initiative.

Process and criteria for research priority setting

There were 3 essential phases in research priority setting, namely pre-

implementation/preparatory, implementation and post-implementation phases.

For the pre-implementation phase, we first identified the three essential groups of

people involved and their functions. These are: 1) Leadership- ensures the funding

and other needed resources, and identifies a technical group. 2) Technical Working

Group – functions as the research, organizational and documentation team 3) Agenda

Setting Participants - research stakeholders who would actively participate in the

process.

6

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Philipp J Chest Dis 20187

Preparatory Phase

On July 26, 2018, the three essential groups and its members were identified. The

leadership group included the current PCCP President Dr. Lenora Fernandez, Board

Member Dr. Virginia de los Reyes, and the current chairman of the research

committee. The technical working group (TWG) was composed of Dr. Luisito Idolor, Dr.

Jubert Benedicto, Dr. Aileen Wang, Dr. Raiza Visita, and Dr. Miriam Lalas). The group

decided to consult Professor Cynthia Cordero from the Department of Clinical

Epidemiology University of the Philippines College of Medicine to guide them on the

agenda setting process. The leadership and technical working group decided to invite

research stakeholders namely Chairs of the PCCP councils, Chairs of the local

chapters, research representatives of training institutions and Consultant advisers of

PCCP.

A vital part of the preparatory phase is contextualization which includes specifying an

over-arching framework. Contextualization included the scope and focus of the

research agenda setting for PCCP, identifying the end-users, the guiding values and

principles to be used and followed, and identifying the capacity of the College and

available resources. It also included the planning for its implementation and

dissemination of the output among the college members. It was important for the

group to gather information or data that were associated with the objectives of the

college and current health needs in the field of respiratory medicine, and to ensure

inclusiveness from different stakeholders and end-users’ concerns and encourage

active participation. Guiding principles such as equity, cost-effectiveness and preferred

type of research were specified at this phase. Also at this phase political and economic

factors that may influence our agenda were identified and how these are aligned with

the national health agenda.

Finally, a context map (see figure 1) was drawn to tie all components by an

overarching framework that explains the rationale behind our health research

prioritization activity and shows how health research prioritization should lead to

improved lung health status of the population.

In this context map (Figure 1), it was decided that the main focus of research will be

chronic airway diseases, infectious diseases, lung malignancy, critical care/vascular,

as well as education and training. These research areas also reflect how the PCCP is

currently organized with its different specialty councils. Outside the box in this

diagram, will be the National Health Research Agenda (NUHRA) that will help guide

our research prioritization; and the Department of Health (DOH), and World Health

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Vol. 19 | Issue 03 | September 2018 8

Organization (WHO), whose policies may influence the agenda and may be our

partners in providing funding and other resources. The goal of this health research

prioritization is to generate researches that will improve health status of Filipinos by

decreasing morbidity and mortality due to lung diseases.

Information Gathering

Before the implementation phase, information that are relevant to health research

(previous agenda, morbidity mortality causes, national health agenda, prevalence and

cost-effectiveness studies) have to be gathered, processed and integrated. It was the

task of the technical working group to gather these relevant information that may be

considered a reference/baseline for the agenda setting participants or situational

analysis for the prioritization exercise.

A previous PCCP research agenda setting workshop in 2006 identified 11 topics of

high research importance. The following are: 1. Tuberculosis, 2. Epidemiologic studies,

3. Chronic obstructive pulmonary disease, 4. Adherence to Clinical Practice Guide-

Figure 1. Contextual Framework

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Philipp J Chest Dis 20189

lines, 5. Lung Cancer treatment outcomes, 6. Mechanical Ventilation, 7. KAP studies,

8. Economic burden of pulmonary diseases, 9. Smoking, 10. Environmental/

occupational studies, and 11. Complementary and alternative medicine. There is

however a clear need to update these priority research areas and to improve the

uptake of the research agenda in terms of actual studies conducted based on this

agenda.

The Philippine National Health Research Agenda has 6 themes comprising the

research priorities, namely: responsive health system, research to enhance and

extend healthy lives (ex. communicable and non-communicable disease), holistic

approaches to health and wellness, health resiliency (ex. occupational &

environmental health), global competitiveness and innovation in health (ex diagnostics;

mapping of health risks & resources), and research in equity and health. The outputs

of these priority areas may be used in the development of personalized medicines,

diagnostics and therapeutics, and in support to the health & clinical practice guidelines

and policies in its identified priority respiratory diseases or conditions, such as

Pneumonia, Tuberculosis, Multidrug-resistant Tuberculosis and Lung Cancer. The

NUHRA is useful in providing a national framework for research areas that PCCP may

venture into. However, its scope may be too broad and there is a need to formulate

more specific research areas that PCCP currently needs.

Burden of pulmonary diseases and local researches

Pulmonary diseases such as PTB, COPD, pneumonia, and lung cancer remain in the

top 10 causes of morbidity and mortality in the country.

According to DOH data in 2013 (Fig.2), the top 10 causes of mortalities included

Pneumonia, lower respiratory tract infection and Tuberculosis of all forms at the 4th, 7th

and 8th places. The tope 10 causes of morbidity (Fig.3) included acute respiratory

infection, Acute Lower respiratory tract infection or Pneumonia, Bronchitis and PTB at

the 1st, 2nd, 5th and 8th place.

More recently, the Institute for Health Metrics and Evaluation (IHME), an independent

global health research center at the University of Washington published the Global

Burden of Diseases 2016 document in LANCET in 2017. This provides a

comprehensive assessment of cause-specific mortality for 264 causes in 195 locations

from 1980 to 2016 with >80,000 different data sources. The top ten diseases causing

mortality among Filipinos in 2016 where identified and three respiratory illnesses such

as Lower respiratory tract infection, Tuberculosis, and COPD ranked 3rd, 5th and 7th

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Vol. 19 | Issue 03 | September 2018

place respectively. While the top respiratory disease causes of morbidity among

Filipinos according to this document were respiratory tract infection and tuberculosis at

2nd and 8th spot. They also identified tobacco use and air pollution as among the top

10 risk factors for mortality and disability among Filipinos (Fig. 4, 5).

In terms of published local researches on lung diseases, it was noted that these were

mostly small observational studies usually initiated by residents and fellows as a

prerequisite for completion of training. The TWG was able to review 105 articles from

three journal archives (PCP Journal, PCCP Journal and Acta Medica) for the past five

years (2013-2018). Among the research topics, majority were on chronic airway

diseases (34%), critical care, vascular and sleep medicine topics at 28%, Infectious

lung disease 25%, ILD/smoking/lung cancer 11% and others 2% (Fig. 6). Majority of

these studies though analytical (56.2%) in design, were mostly observational studies

(93.2%) and only 0.7% were interventional studies (Fig.7). It was important also to

note that the sample size in the majority of these studies were small and mostly done

at a single-center setting. Nonetheless, this list of local studies (Appendix 1) is helpful

in terms of giving us an idea of what has already been done as reference and baseline

for the agenda setting.

10

Fig. 2. Leading Causes of Mortality, DOH 2013

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Philipp J Chest Dis 201811

Fig. 3. Leading Causes of Morbidity, DOH 2014

Fig. 4. Leading Causes of Death & Disability. Global Burden of Diseases 2016

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Vol. 19 | Issue 03 | September 2018 12

Chronic Airway Disease; 34%

Crit Care/Vascular/Sleep; 28%

ILD/Malignancy/Smoking/Air Pollution; 11%

Infectious lung diseases; 25%

Others; 2%

Fig. 6. Distribution of Researches by topic.

The mortality, morbidity, and local research reviews supported our conceptual

framework in emphasizing our identified priority research areas. The information

gathered from the preparatory phase also served as the spring board to generate the

initial list of topics.

40

6

Observational; 55

Interventional; 4

0

10

20

30

40

50

60

70

Descriptive Meta-analysis Analytical

Fig. 7. Classification of Local Researches on lung diseases by Study Design

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Philipp J Chest Dis 201813

Implementation Phase

The different PCCP councils and chapters submitted a list of priority research topics to

be included in the research agenda based on their recently completed research

projects, ongoing researches and planned research projects. On August 13, 2018, an

initial list of research topics was generated by the technical working group based on the

gathered information during the preparatory phase and the contribution of the PCCP

councils and chapters.

On August 16, 2018, the Leadership and the TWG drew a criteria for ranking the initial

list of research topics. The criteria included: magnitude of the problem (based on

prevalence, urgency, burden to population); likelihood that results of research can

influence practice (ex. health policy, clinical practice guidelines); likelihood that results

of research can potentially decrease disease burden; feasibility of the research based

on existing resources of PCCP; and if the research can be ethically conducted (Table

1). The assigned weight per criteria (multiplier) was also decided on, with the criterion

of magnitude of the problem being assigned the highest weight (Table 2).

On September 1, 2018, the research agenda setting workshop was held at the Lung

Center of the Philippines. This was attended by representatives of the various councils,

chapters, and PCCP training institutions, technical working group, and the PCCP

leadership. Professor Cynthia Cordero and Dr. Virginia de los Reyes served as the

facilitators for this workshop.

There were a total of 27 research topics that were generated from the input of the

different councils, chapters, training institutions and the technical working group (See

Table 3).

The participants were asked to score and rank the various topics based on the criteria

presented by the TWG. The participants were also divided into clusters as follows

based on the concept map: obstructive airway disease, critical care/vascular/sleep,

interstitial lung disease/malignancy/smoking/air pollution, infectious lung disease and

Table 1: Criteria for Ranking

1. Magnitude of the problem (based on prevalence, urgency, burden to population)

2. Likelihood that results of research can influence practice (ex. Health policy, clinical

practice guidelines)

3. Likelihood that results of research can potentially decrease disease burden

4. Is the research feasible based on existing resources of PCCP?

5. Can the research be ethically conducted?

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Vol. 19 | Issue 03 | September 2018 14

Table 2: Scoring Worksheet

Criteria Magnitude

of the

problem

Likelihood

that

results of

the

research

can

influence

practice

Likelihood

that the

results of

the

research

can

potentially

decrease

disease

burden

Is the

research

feasible

based on

existing

resources

of PCCP?

Can the

research

be

ethically

conducted

?

Score

Assigned

weight per

criteria

(multiplier)

2 1 1 1 1

Proposed

research

topic

SCORE TOPICS PER CRITERIA (from 1-10); 10 as the highest score

education/training. Aside from scoring and ranking the general research topics, the

groups were tasked to formulate clinical questions using the PIOM format as well as

generate related new topics. The research questions were not meant to restrict the

agenda’s field of study, but rather to assist potential researchers in formulating their own

research questions.

After the presentation of each group, the over-all ranking of topics as scored by the

participants were presented. The final topics were agreed upon during the open forum

wherein ranking and consensus were used in reaching decisions on prioritization.

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Philipp J Chest Dis 201815

Obstructive airway disease

1. The burden of obstructive lung disease II study

2. Study of national asthma prevalence

3. Non-adherence to pharmacologic treatment in the Clinical Profile and Survival

Study of Filipino COPD patients (CPASS) cohort

4. Non-adherence to non-pharmacologic treatment in the CPASS cohort

5. Real-world experience/studies of asthma management of both MDs and

non-MDs

Critical Care/Vascular/Sleep

1. Prevalence of pulmonary embolism among critically-ill patients

2. Physician knowledge and attitude on OSA

3. ARDS registry

4. Community-based prevalence of OSA in the Philippines

5. Patient adherence to PAP therapy

6. Local version of Epworth Sleepiness Scale

ILD/Malignancy/Smoking/Air Pollution

1. Development of evidence-based recommendations on the use of e-cigarette

2. Clinical profile of pulmonary malignancies among Filipinos

3. Clinical profile of e-cigarette users in Metro Manila

4. KAP of pulmonologists on occupational lung disease

5. Survey of most common occupational lung diseases in the Philippines

6. Exposure to air pollution of workers who commute daily in Metro Manila

7. Accuracy of PET scan in differentiating TB vs malignancy

Infectious lung disease

1. Evaluation of treatment practices among pulmonologists for TB retreatment cases

2. Local guidelines for TB pre-employment

3. Surveillance of commonly isolated respiratory pathogens

4. Practices among pulmonologists regarding vaccination

5. Isoniazid prophylaxis treatment among healthcare workers with latent TB infection

6. Profile of bronchiectasis patients in the Philippines

Education/Training

1. Healthcare utilization of different pulmonary diseases

2. Assessing relevance of required pulmonary procedures and degree of

preparedness of PCCP graduates in their performance

3. Formulation of outcome-based curriculum for PCCP pulmonary fellowship

program

Table 3. List of Research Topics

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Vol. 19 | Issue 03 | September 2018 16

CRITICAL CARE/VASCULAR/SLEEP MEDICINE

CLUSTER RANKING

Critical Care/Vascular/SleepAverage

scoreRank

Prevalence of pulmonary embolism among critically-ill

patients47.13 1

Physician knowledge and attitude on OSA 46.50 2

ARDS registry 46.17 3

Community-based prevalence of OSA in the Philippines 45.29 4

Patient adherence to PAP therapy 43.88 5

Local version of Epworth Sleepiness Scale 43.67 6

Research topic 1: What are the risk factors for CTPA diagnosed PE?

Identified initiator: PCCP Council on Critical Care, Training institutions

Timeline: 4-5 years

P-CTPA diagnosed Pulmonary embolism

O-Clinical Characteristics

M-Observational, survey questionnaire

Research topic 2: Among pulmonologists, what is the state of awareness and

practice on OSA?

Identified initiator: PCCP Council on Sleep, Training institutions

Timeline: 2 years

P-practicing pulmonologist members of the PCCP

O-Knowledge, attitude and practices

M-Observational, survey questionnaire

Research topic 3: What is the clinical profile of ARDS patients admitted in the

ICU of PCCP accredited hospitals?

Identified initiator: PCCP Council on Critical Care, Training institutions

Timeline: 4-5 years

P-ICU patients diagnosed with ARDS

O-Clinical Characteristics of ARDS patients admitted at the ICU

M-Observational, survey questionnaire

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Philipp J Chest Dis 201817

Research topic 4: Among hypertensive patients what is the prevalence of those

at risk for OSA?

Identified initiator: PCCP Council on Sleep Medicine, Training institution

Timeline: 3 years

P-Hypertensive patients

O-Prevalence of OSA risk factors

M-Observational, use of STOP-BANG questionnaire

Research topic 5: Among PSG-diagnosed OSA patients, what is the adherence to

PAP therapy?

Identified initiator: PCCP Council on Sleep

Timeline: 3-5 years

P-PSG diagnosed OSA patients

O-adherence data through self-report and machine compliance use data

M-Descriptive, Questionnaire, compliance data

OBSTRUCTIVE AIRWAY DISEASE

CLUSTER RANKING

Obstructive airway diseaseAverage

scoreRank

The burden of obstructive lung disease II study 50.54 1

Study of national asthma prevalence 50.29 2

Non-adherence to pharmacologic treatment in the CPASS

cohort49.33 3

Non-adherence to non-pharmacologic treatment in the CPASS

cohort47.46 4

Real-world experience/studies of asthma management of both

MDs and non-MDs46.33 5

Research topic 1: What is the prevalence, burden and risk factors for COPD in

urban and rural settings in the Philippines? Burden of Chronic Obstructive

Pulmonary Disease (BOLDer)

Identified initiator: PCCP COPD Council, Chapters, Training Institutions

Timeline: 3 years

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Vol. 19 | Issue 03 | September 2018 18

P: all adults > 40 years of age residing in selected rural communities and urban cities

nationwide; multi-stage random sampling procedure

• By region, by province, by municipality

• Metro-cities (NCR, Metro Cebu, Metro Davao)

O: prevalence, burden and risk factors(smoking, other environmental/occupational risk

factors)

M: Cross sectional analytic; Cross Sectional survey using CORE questionnaire,

Spirometry

Research topic 2: Non-adherence to pharmacologic treatment in the Clinical Profile

and Survival Study of Filipino COPD patients (CPASS) cohort

2.1. Among physicians managing the CPASS COPD cohort, is there a difference in the

adherence to the GOLD 2017 recommendations?

Identified initiator: PCCP COPD Council, Chapters, Training Institutions

Timeline: 3 years

Significance: Strategize educational intervention for physicians

P: FPCCP vs non-FPCCP pulmo trained doctors, internists, general practitioners

O: adherence to the GOLD 2017 recommendations

M: Observational Retrospective (or Prospective) Cohort Study; survey

2.2. Among the CPASS cohort, what are the factors predictive of or are associated with

patients’ non-adherence to pharmacologic treatment?

Initiator: PCCP / COPD Council

Significance: Strategize educational intervention for patients

P: CPASS subjects who are non-adherent to pharmacologic management

O: Prevalence of non-adherence due to: Economic reasons, Complex drug regimens,

Drug is ineffective, Too many drugs, Side effects, Difficult to use, Inadequate instructions

from physician

M: Descriptive Study; questionnaire

2.3. Among the CPASS cohort, is management adherent to the GOLD 2017 guidelines

associated with or predictive of better outcomes compared to non-adherent

management?

Initiator: PCCP / COPD Council

Significance: Formulation of CPG guidelines

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Philipp J Chest Dis 201819

P: CPASS subjects

O: exacerbation rates, symptom control, QOL, health care utilization

M: Observational Retrospective (or Prospective) Cohort Study; use of questionnaires,

CAT, SGRQ

Research topic 3: Non-adherence to non-pharmacologic treatment in the CPASS

cohort

3.1. What is the QOL of COPD patients undergoing pulmonary rehabilitation compared

with those not on pulmonary rehabilitation?

Initiator: PCCP / COPD Council

P: CPASS patients

I: Pulmonary Rehabilitation (6 weeks and above)

O: Quality of life (CAT Score and Six Minute Walk Distance; Borg, Dyspnea Scale

M: cross-sectional multi-center survey

3.2. Frequency of exacerbation among COPD patients undergoing PR as compared to

those not on PR

3.3. Survival Rate of COPD patients undergoing PR compared to those not on PR

Research topic 4. Study of National Asthma Prevalence

Initiator: PCCP /Asthma Council / PCCP Chapters

4.1 Among clinically diagnosed asthma patients, what is the level of asthma control?

P: adult asthmatic patients (physician-diagnosed, current asthma symptoms or taking

asthma medications); rural and urban, community and hospital-based

O: Asthma control (GINA criteria for asthma control)

M: Cross-sectional descriptive survey; use of ACT, Questionnaire (socio-demographic

data, respiratory symptoms, risk factors), spirometry with bronchodilator testing

4.2 Among patients diagnosed with asthma by spirometry and GINA definition, what is

the national prevalence, current severity, and GINA-defined level of control?

P: Asthma patients diagnosed by spirometry

O: national prevalence, current severity, and GINA-defined level of control

M: cross-sectional descriptive study, questionnaire, spirometry

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Vol. 19 | Issue 03 | September 2018 20

4.3 Among patients with asthma, what are the prevalence of step 4-5 GINA/ERS-

defined severe asthma and determinants of severity?

4.4 Among adult Filipinos with asthma, is their current management adherent to

current national and GINA recommendations?

(Can be combined with previous surveys)

P: adult Filipinos with asthma managed by GP, IM, specialist, or self-managed

O: adherence to national and GINA recommendations

M: cross-sectional descriptive study, questionnaire

Research topic 5. Real-world experience (RWE) studies of asthma

Initiator: Asthma Council, PCCP Chapters, training institutions

5.1 Among physicians taking care of adult asthmatics in their outpatient clinics,

what are their knowledge, attitude and current practices in the diagnosis and

management of asthma?

P: Specialists, IMs, GPs

O: KAP measures

M: cross-sectional descriptive study, use of questionnaires to measure knowledge and

attitude. To measure practice: Asthma Council to formulate typical asthma cases (GINA

Steps 1-5) and develop questions on diagnosis and management

5.2 Among adult patients with asthma, what are the factors that independently

predict or are associated with increased exacerbations and poor outcome?

P: GINA-defined controlled vs uncontrolled asthma (visited the emergency room at least

2x in the past year)

O: exacerbations

M: Case-control, cross-sectional survey or prospective cohort

5.3 Among adult patients consulting at outpatient clinics, what are the

comparative rates in the prescription of oral medications versus inhalers in their

maintenance management?

P: asthma patients at OPD

O: rates in the prescription of oral medications versus inhalers in the maintenance

management of asthma; specialists vs internists vs general practitioner

M: Cross Sectional Survey; can be social media sourced

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Philipp J Chest Dis 201821

5.4 Among adult patients consulting at outpatient clinics, are asthma outcomes

better among patients given ICS/LABA for at least 6 months by MDI vs dry powder

inhaler?

P: adult asthmatic patients consulting at outpatient clinics

I: ICS/LABA for at least 6 months by MDI vs dry powder inhaler

O: exacerbation rates, GINA control status, health care utilization, ACT, asthma QOL

M: Pragmatic RCT or prospective cohort study

5.5 Among adult patients consulting at outpatient clinics, what are the errors in

inhalational technique (pMDI vs DPI)?

P: adult asthmatic patients consulting at outpatient clinics using pMDI or DPI

O: errors in inhalational technique

M: Observational study

5.6 Among adult patients consulting at outpatient clinics, will an inhaler

technique instruction program provide better asthma outcomes compared to

standard practice?

(Can be combined with previous study)

P: adult asthmatic patients consulting at outpatient clinics

I: inhaler technique instruction program

O: exacerbation rates, GINA control status, health care utilization, ACT, asthma QOL

M: Pragmatic RCT or Prospective Cohort study

Research topic 6. Healthcare utilization for asthma exacerbations

PCCP / Asthma council initiated; Philhealth

Among adult asthmatic patients admitted for acute exacerbation included in the Phil

Health database:

1. What are the direct and indirect costs of healthcare utilization? Method: Health

economics measurement

2. What are the risk factors associated with hospital admission? Method: case control /

cross sectional

3. What are the characteristics and outcomes associated with more severe asthma

exacerbation? Method: case control

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Vol. 19 | Issue 03 | September 2018 22

INFECTIOUS LUNG DISEASE

CLUSTER RANKING

Infectious lung disease

Average

score Rank

Evaluation of treatment practices among pulmonologists for

TB retreatment cases 53.04 1

Local guidelines for TB pre-employment 52.79 2

Surveillance of commonly isolated respiratory pathogens 48.67 3

Practices among pulmonologists regarding vaccination 48.33 4

Isoniazid prophylaxis treatment among healthcare workers

with latent TB infection 47.96 5

Profile of bronchiectasis patients in the Philippines 47.83 6

Research topic 1: Evaluation of treatment practices among pulmonologists for

TB retreatment cases

Multi-center; Council or chapter initiated

1.1 Comparison of Programmatic (DOTS) vs non programmatic (clinic) treatment

for retreatment cases

P: TB retreatment cases

I: Programmatic (DOTS) vs non programmatic (clinic) treatment

O: cure rate, completion rate, treatment failure, relapse

M: cross-sectional cohort

1.2 Knowledge Attitude Practices of physicians regarding TB retreatment cases

Research topic 2: Local guidelines for TB pre-employment

PCCP, Council initiated

• Knowledge Attitude Practices of physicians regarding TB pre-employment

• Adherence to current TB pre-employment guidelines

• Development of updated guidelines

Research topic 3: Surveillance of commonly isolated respiratory pathogens

Private hospitals/PCCP training institutions

P: hospitalized patients with community acquired pneumonia

O: isolated respiratory pathogens, drug sensitivity

M: observational study; standardized collection of respiratory specimen

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Philipp J Chest Dis 201823

Research topic 4: Practices among pulmonologists regarding vaccination

P: patients seen at health facilities

O: vaccination rate; type of vaccinations given; facilitating and hindering factors

M: observational study; patient survey

Research topic 5: Isoniazid prophylaxis treatment among healthcare workers

with latent TB infection

TB Council, PCHRD

P: healthcare workers with latent TB infection

I: Isoniazid prophylaxis treatment

O: prevention of active PTB over 3-5 years

M: RCT

Research topic 6: Risk factors for poor treatment outcomes of drug sensitive TB

PCCP/Training Institutions/Chapters; National TB Program funding

P: Patients with drug sensitive tuberculosis under DOTS setting on Category 1

treatment

O: cure, treatment completed, lost to follow up, treatment failure, relapse, adverse

events

M: case control study

Research topic 7: Profile of bronchiectasis patients in the Philippines (ANOLD

Bronchiectasis study)

What are the characteristics of patients with bronchiectasis in the Philippines?

PCCP council initiated; Sponsored by South Korean Study Group

Timeline: 3 years

P: Filipino patients with non-cystic fibrosis bronchiectasis

O: etiology; clinical characteristics (phenotype, etiology:, exacerbation, hospitalization,

mortality), disease burden

M: cross sectional study; use of questionnaires, imaging, PFT, bacteriologic studies

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Vol. 19 | Issue 03 | September 2018 24

LUNG MALIGNANCY/ILD/OLD/SMOKING/AIR POLLUTION

CLUSTER RANKING

ILD/Malignancy/Smoking/Air Pollution

Average

score Rank

Development of evidence-based recommendations on the use of

e-cigarette 49.58 1

Clinical profile of pulmonary malignancies among Filipinos 48.71 2

Clinical profile of e-cigarette users in Metro Manila 47.83 3

KAP of pulmonologists on occupational lung disease 47.33 4

Survey of most common occupational lung diseases in the

Philippines 46.75 5

Exposure to air pollution of workers who commute daily in Metro

Manila 45.79 6

Accuracy of PET scan in differentiating TB vs malignancy 42.63 7

Research topic 1: Exposure to air pollution of workers who commute daily in

Metro Manila

PCCP Council initiated

Among jeepney commuters along major thoroughfares in Metro Manila, does the level

of total particulate matter exposure correlate with their lung function?

P- Jeepney commuters along major thoroughfares in Metro Manila

O-Lung Function

M-cross-sectional study, case control; total particulate matter exposure monitoring;

spirometry; respiratory symptoms

Research topic 2: What are the Knowledge, Attitude and Practices of

Pulmonologists in the Philippines towards Occupational Lung Disease?

P: Pulmonologists in the Philippines

O: KAP

M: Descriptive, questionnaire

Research topic 3: What is the prevalence of Occupational Lung Disease in the

Philippines?

P: Major Cities in the Philippines; representative industries

O: Prevalence of common occupational lung diseases, risk factors

M: Descriptive, questionnaire, interviews, spirometry

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Philipp J Chest Dis 201825

Research Topic 4. Development of evidence-based recommendations on the use

of e-cigarette

4.1. What is the clinical profile of e-cigarette users in Metro Manila?

P: E-cigarette users in Metro Manila

O: Clinical profile

M: Descriptive; use of questionnaires

4.2. What is the relationship between E-cigarette use and smoking cessation?

P: conventional cigarette smokers vs dual (conventional and E-cigarette) smokers in

urban cities

I: E-cigarette

O: quit attempt rates, smoking cessation rates

M: prospective cohort study

Research Topic 5: What is the clinical profile of patients with pulmonary

malignancies based on an analysis of the Tumor Registry?

P: Patients with pulmonary malignancy registered with the Tumor Registry

O: Clinical profile, incidence of pulmonary malignancy among smokers vs non-

smokers, second hand smokers

M: Descriptive; use of questionnaire, data base

Research Topic 6: Accuracy of PET scan in differentiating TB vs malignancy

What is the reliability of the PET-CT in the setting of high TB burden in terms of

staging of lung malignancy?

P: Patients with lung malignancy with PET-CT

O: Sensitivity and specificity of PET-CT for staging of lung malignancy

M: cross sectional study

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Vol. 19 | Issue 03 | September 2018 26

CLUSTER RANKING

Education/Training

Average

score Rank

Healthcare utilization of different pulmonary diseases 48.75 1

Assessing relevance of required pulmonary procedures and

degree of preparedness of PCCP graduates in their performance 48.71 2

Formulation of outcome-based curriculum for PCCP pulmonary

fellowship program 48.54 3

EDUCATION/TRAINING

Research Topic 1: Assessing relevance of required pulmonary procedures and

degree of preparedness of PCCP graduates in their performance

Initiator: PCCP, Training Institutions, Chapters

Timeline: 1 to 2 years

What is the relevance of the required pulmonary procedures and degree of

confidence in performing them in clinical practice among PCCP- accredited

pulmonologists?

P-All graduates of PCCP accredited pulmonary fellowship training program

O-Relevance of required procedure and confidence in the performance of the

procedure

M-Observational study via survey/ questionnaires (thoracentesis, bronchoscopy,

pleurodesis and pleural biopsy)

Research Topic 2: Health care utilization of different pulmonary diseases

Initiator: PCCP through different institutions / chapters

Timeline: 2-3 years

What is the cost of healthcare utilization among admitted patients with

pulmonary diseases (COPD, Asthma, Pneumonia, Lung CA, and PTB) in the

Philippines?

P- patients admitted for pulmonary diseases

O- cost of healthcare utilization

M- cross-sectional study; review of Philhealth data base

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Philipp J Chest Dis 20181927

OVER ALL RANKING Average score

1. Evaluation of treatment practices among pulmonologists for TB

retreatment cases53.04

2. Local guidelines for TB pre-employment 52.79

3. The burden of obstructive lung disease II study 50.54

4. Study of national asthma prevalence 50.29

5. Development of evidence-based recommendations on the use of e-

cigarette49.58

6. Non-adherence to pharmacologic treatment in the CPASS cohort 49.33

7. Healthcare utilization of different pulmonary diseases 48.75

8. Clinical profile of pulmonary malignancies among Filipinos 48.71

9. Assessing relevance of required pulmonary procedures and degree

of preparedness of PCCP graduates in their performance48.71

10. Surveillance of commonly isolated respiratory pathogens 48.67

11. Formulation of outcome-based curriculum for PCCP pulmonary

fellowship program48.54

12. Practices among pulmonologists regarding vaccination 48.33

13. Isoniazid prophylaxis treatment among healthcare workers with

latent TB infection47.96

14. Clinical profile of e-cigarette users in Metro Manila 47.83

15. Profile of bronchiectasis patients in the Philippines 47.83

16. Non-adherence to non-pharmacologic treatment in the CPAS cohort 47.46

17. KAP of pulmonologists on occupational lung disease 47.33

18. Prevalence of pulmonary embolism among critically-ill patients 47.13

19. Survey of most common occupational lung diseases in the

Philippines46.75

20. Physician knowledge and attitude on OSA 46.5

21. Real-world experience/studies of asthma management of both MDs

and non-MDs46.33

22. ARDS registry 46.17

23. Exposure to air pollution of workers who commute daily in Metro

Manila45.79

24. Community-based prevalence of OSA in the Philippines 45.29

25. Patient adherence to PAP therapy 43.88

26. Local version of Epworth Sleepiness Scale 43.67

27. Accuracy of PET scan in differentiating TB vs malignancy 42.63

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Vol. 19 | Issue 03 | September 2018 28

Post-implementation Phase

The last phase is the post-implementation phase wherein the process and results of

the research agenda setting workshop will be reported. The manuscript of the

workshop proceedings will be disseminated to the membership. Monitoring and

evaluation of the uptake of the research topics in the agenda will be carried out by

PCCP’s Research Committee.

PCCP has adopted measures to strengthen its research capabilities through the

formation a Research Committee with a fixed two year term. Among the

responsibilities of the Research Committee will be to carry out dissemination,

implementation and monitoring and evaluation of the PCCP Research agenda.

Additionally, it will oversee the approval of research grant proposals and funding. The

Research committee had reviewed and revised the policies, rules and regulations

regarding research grant applications with the objective of increasing the support of

PCCP for relevant research by its members. (Appendix 2: Revised guidelines on

research grant applications). The PCCP Research Committee will also link up with

partners in the government and private sectors who will be providing additional

funding and other resources.

This research agenda would hopefully set the direction for the research activities of

the College for the next five years. However, a fair and transparent appeal system

will be put in place. This process is essential to allow important topics that might

have been overlooked to be included and ensure that the agenda remains dynamic

and relevant.

A timeline of the research agenda setting process is outlined below (Table 3).

For queries on conduct, funding, or appeals process, please contact PCCP Research

Committee thru philchest.org, [email protected].

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Philipp J Chest Dis 201829

Table 3. Timeline of Research Agenda Setting Process

Tasks Jul 30-Aug 5 Aug 6-12 Aug 13-19 Aug 20-26 Aug 27-30 Sep-01 Oct- Jan Feb Mar 2018 2023

Defining the context;

concept map

July 26-prep.

mtg

Planning for M&E

Information gathering

Follow up

attendees–follow up of

research topics

Generate initial list of

topics

Choosing & applying

criteria for ranking

Deciding on research

priorities

Aug 13- mtg of

TWG

Aug 16-mtg.

TWG

Reporting prioritization

process & results

Sep 1-RA

Workshop

Write up of report

Meet with Research Board

Disseminating the research

agenda

Write-up &

Publish the

document

Meet with

funding agencies

Distribute

manuscripts

during

Monitoring & Evaluation Every 6 months

Mar 2019

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Vol. 19 | Issue 03 | September 2018 30

N

107

58

102

78

26

165

165

254

118

399

PO

PU

LA

TIO

N

Adult a

sth

ma a

nd C

OP

D p

atie

nts

in U

P P

GH

adult p

atie

nts

in

LC

P w

ith

bro

nchie

cta

sis

Asth

ma p

atie

nts

in

LC

P

Adult P

atie

nts

in

LC

P e

valu

ate

d

for

lung r

esectio

n

patie

nts

adm

itte

d in

PG

H w

ith

hem

opty

sis

Jan 2

011 t

o D

ec 2

015

CO

PD

patie

nts

seen in

LC

P c

linic

s

CO

PD

patie

nt

in L

CP

clin

ic

Adult p

ost

TB

tre

ate

ment w

ith P

FT

CO

PD

patients

seen in c

linic

s

revie

w o

f chart

s o

f C

OP

D p

atie

nt

adm

itte

d in

LC

P f

or

exacerb

atio

n

SP

EC

IFIC

Cro

ss-s

ectio

nal

Pro

spective

Pro

spective

cro

ss-s

ectio

nal

Pro

spective

cohort

Retr

ospective

Retr

ospective

Cro

ss-s

ectio

nal

Pro

spective

cro

ss-s

ectio

nal

Pro

spective

cro

ss-s

ectio

nal

Retr

ospective

cro

ss-s

ectio

nal

ST

UD

Y D

ES

IGN

Descrip

tive

Descrip

tive

Descrip

tive

Descrip

tive

Descrip

tive

Descrip

tive

Descrip

tive

Descrip

tive

Descriptive

Descrip

tive

CL

US

TE

R

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

Chro

nic

Airw

ay

Dis

ease

TIT

LE

(R

efe

ren

ce)

1.P

revale

nce o

f A

sth

ma

-CO

PD

Overla

p S

yndro

me (

AC

OS

)

in P

atie

nts

Pre

sentin

g w

ith A

sth

ma o

r C

OP

D in t

he O

PD

of

the U

P-P

GH

Sectio

n o

f P

ulm

onary

Medic

ine:

A P

ilot S

tudy

(PJC

D v

ol 18 #

3)

2.C

linic

al C

orr

ela

tio

n o

f th

e R

adio

logic

Fin

din

gs a

nd

Pulm

onary

Fu

nctio

n o

f P

atie

nts

with B

ronchie

cta

sis

: a L

ung

Cente

r of

the P

hili

ppin

es E

xperie

nce (

PJC

D v

ol 18 #

3)

3.C

om

para

tive s

tudy o

n t

he c

linic

al p

rofile

, tr

eatm

ent

response a

nd le

vel of

asth

ma c

ontr

ol betw

een e

lderly a

nd

adult a

sth

matic p

atie

nts

seen a

t th

e a

sth

ma c

linic

–O

PD

of

the L

ung C

ente

r of

the P

hili

ppin

es (

PJC

D v

ol 17 #

2)

4.C

ohort

Stu

dy o

n t

he A

pplic

abili

ty o

f th

e U

pdate

d 2

015

Lung C

ente

r of

the P

hili

ppin

es A

lgorith

m o

n P

re-o

pera

tive

Ris

k A

ssessm

ent as a

Pre

dic

tor

of

Post-

pera

tive P

ulm

onary

Com

plic

atio

ns (

PJC

D V

ol 18 #

4 O

ct-

Dec 2

017)

5.C

linic

al P

rofile

and O

utc

om

e o

f P

atie

nts

Pre

sentin

g w

ith

Hem

opty

sis

Adm

itte

d in

a T

ert

iary

Hospital P

rofile

and

Outc

om

e o

f P

atie

nts

Pre

sentin

g w

ith H

em

opty

sis

Adm

itte

d

in a

Te

rtia

ry H

ospital

6.P

revale

nce a

nd C

hara

cte

ristics o

f th

e T

hre

e C

linic

al

Phenoty

pes o

f C

hro

nic

Obstr

uctive P

ulm

onary

Dis

ease a

t

Lung C

ente

r of

the P

hili

ppin

es (

PJC

D v

ol 18 #

3)

7.C

linic

al P

rofile

of

Patie

nts

with C

OP

D A

ccord

ing t

o G

OLD

2014 S

een a

t th

e O

utp

atie

nt

Depart

ment

of

Lung C

ente

r of

Th

e P

hili

ppin

es (

PJC

D v

ol 17 #

4)

8.P

revale

nce o

f C

hro

nic

Obstr

uctive P

ulm

onary

Dis

ease

am

ong p

atie

nts

pre

vio

usly

tre

ate

d f

or

Pulm

onary

Tu

berc

ulo

sis

in

Manila

(P

reC

OP

T):

A m

ultic

ente

r stu

dy

9.T

he P

revale

nce o

f P

erip

hera

l A

rteria

l D

isease a

mong

Fili

pin

o C

hro

nic

Obstr

uctive P

ulm

onary

Dis

ease P

atie

nts

at

the O

utp

atie

nt

Depart

ment of

the L

ung C

ente

r of

the

Phili

ppin

es (

PJC

D v

ol 17 #

4)

10.B

acte

ria

l P

ath

ogens o

f P

atie

nts

with C

hro

nic

Obstr

uctive

Pulm

onary

Dis

ease (

CO

PD

) A

dm

itte

d for

Acute

Exacerb

atio

n a

t th

e L

ung C

ente

r of

the P

hili

ppin

es in

2011

2014 (

PJC

D v

ol 17 #

4)

Appendix I. Review of Local Researches

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Philipp J Chest Dis 201831

N

98

,81

3

60

PO

PU

LA

TIO

N

Ad

ult a

dm

itte

d p

atie

nts

du

e to

Pn

eu

mo

nia

or

Bro

nch

iecta

sis

in IE

22

stu

die

s in

clu

de

C

OP

D

pa

tie

nts

an

d n

ote

d m

ort

alit

y

with

or

with

ou

r B

eta

blo

cke

rs

2 s

tud

ies

3 R

CT

s 4

,62

5 p

atie

nts

mo

d-

se

ve

re C

OP

D

SP

EC

IFIC

RC

T

Me

ta-a

na

lysis

Me

ta-a

na

lysis

Me

ta-a

na

lysis

Me

ta-a

na

lysis

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

ST

UD

Y

DE

SIG

N

Inte

rve

ntio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

TIT

LE

(R

efe

ren

ce

)

11

.Eff

ective

ne

ss o

f M

ech

an

ica

l C

ou

gh

Assis

t

(In

su

ffla

tor-

Exsu

ffla

tor)

am

on

g H

osp

ita

lize

d P

atie

nts

:

An

Op

en

-La

be

l R

an

do

miz

ed

Con

tro

l S

tud

y o

f

Me

ch

an

ica

l C

ou

gh

Assis

t (I

nsu

ffla

tor-

Exsu

ffla

tor)

am

on

g H

osp

ita

lize

d P

atie

nts

: A

n O

pe

n-L

ab

el

Ran

do

miz

ed

Con

tro

l S

tud

y (

PJC

D v

ol 1

8 #

1)

12

.Sa

fety

an

d b

en

efits

of b

eta

-blo

cke

rs in

ch

ron

ic

ob

str

uctive

pu

lmo

na

ry d

ise

ase

: a

re

vie

w o

f cu

rre

nt

evid

en

ce

an

d m

eta

-an

aly

sis

(P

JC

D v

ol 1

9 #

1)

13

.Me

ta-a

na

lysis

on

th

e u

se

of

Sta

tin

s in

Chro

nic

Ob

str

uctive

Pu

lmo

na

ry D

ise

ase

pa

tie

nts

(P

JC

D v

ol

17

#3

)

14

.Co

mp

ari

so

n o

f G

lyco

pyrr

on

ium

plu

s In

da

ca

tero

l

co

mp

are

d to

In

ha

led

Cort

ico

ste

roid

s p

lus L

on

g-A

ctin

g

Be

ta-A

go

nis

ts in

Pa

tie

nts

with

Ch

ron

ic O

bstr

uctive

Pu

lmo

na

ry D

ise

ase

: A

Me

taA

na

lysis

(P

JC

D v

ol 1

8

#1

)

15

.Eff

ica

cy a

nd

Sa

fety

of L

on

g-A

ctin

g B

eta

-Ag

on

ists

(LA

BA

) P

lus L

on

g-A

ctin

g M

usca

rin

ic A

nta

go

nis

ts

ve

rsu

s L

AB

A P

lus In

ha

led

Cort

ico

ste

roid

s in

Ch

ron

ic

Ob

str

uctive

Pu

lmo

na

ry D

ise

ase

: A

Me

ta-A

na

lysis

(PJC

D v

ol 1

8 #

1)

16

.A C

om

pa

rative

Stu

dy o

n P

ulm

on

ary

Fu

nctio

n T

est

resu

lts b

etw

ee

n m

orr

is a

nd

th

e F

ilip

ino

Sta

nd

ard

s

17

.Asso

cia

tio

n b

etw

ee

n T

um

or

Ne

cro

sis

Fa

cto

r-α

-

30

8G

/A P

oly

mo

rph

ism

an

d C

hro

nic

Ob

str

uctive

Pu

lmo

na

ry D

ise

ase

in

Pa

tie

nts

of th

e U

niv

ers

ity o

f

Sa

nto

To

ma

s H

osp

ita

0 (

PJC

D v

ol 1

7 #

3)

18

.No

rma

l S

tan

da

rds fo

r V

en

tila

tory

Fu

nctio

n te

st in

Ad

ult F

ilip

ino

s

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Vol. 19 | Issue 03 | September 2018 32

N 18

11

7

7,2

02

63

15

9

35

PO

PU

LA

TIO

N

Po

st T

B t

rea

ted

pa

tie

nts

se

en

in M

DH

, w

ith

PF

T

Se

nio

r m

ed

ica

l re

sid

en

ts

20

ye

ars

old

an

d a

bo

ve

asth

ma

pa

tie

nts

pa

tie

nts

dia

gn

ose

d w

ith

Asth

ma

or

CO

PD

CO

PD

pa

tie

nts

CO

PD

pa

tie

nts

in

PH

C

SP

EC

IFIC

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

co

ho

rt

Pro

sp

ective

co

ho

rt

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

Ch

ron

ic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

TIT

LE

(R

efe

ren

ce

)

19

.Air

flo

w o

bstr

uctio

n a

mo

ng

pre

vio

usly

tre

ate

d

pu

lmo

na

ry tu

be

rcu

losis

no

nsm

oke

rs in

Ma

nila

Docto

rs H

osp

ita

l (P

JC

D v

ol 1

9 #

1)

20

.Kn

ow

led

ge

an

d U

se

of S

pir

om

etr

y fo

r th

e

Dia

gn

osis

of C

hro

nic

Ob

str

uctive

Pu

lmo

na

ry D

ise

ase

Am

on

g S

en

ior

Me

dic

al R

esid

en

ts in

Me

tro

Ma

nila

(PJC

D v

ol 1

8 #

1)

21

.Pre

va

len

ce

of A

sth

ma

Am

on

g F

ilip

ino

Ad

ults

ba

se

d o

n th

e N

atio

na

l a

nd

Hea

lth

Su

rve

y (

NN

HeS

)

(PJIM

vo

l 5

2 #

4)

22

.Pre

va

len

ce

of A

sth

ma

-CO

PD

Ove

rla

p S

yn

dro

me

(AC

OS

) A

mo

ng

Pa

tie

nts

Pre

se

ntin

g w

ith

Asth

ma

of

CO

PD

in

th

e O

PD

of th

e U

P-P

GH

Se

ctio

n o

f

Pu

lmo

na

ry M

ed

icin

e: A

Pilo

t S

tud

y (

PJC

D v

ol 1

8 #

1)

23

.Pre

dic

tive

Eq

ua

tio

n o

f Im

pu

lse

Oscill

om

etr

y (

IOS

)

Pa

ram

ete

rs in

Mid

dle

an

d A

dva

nce

d A

ge

Ad

ults w

ith

an

d w

ith

ou

t O

bstr

uctive

Lu

ng

Dis

ea

se

(P

JC

D v

ol 1

9

#1

)

24

.Asse

ssm

en

t o

f in

ha

latio

na

l te

ch

niq

ue

am

on

g a

du

lt

pa

tie

nt w

ith

ob

str

uctive

air

wa

y d

ise

ase

at th

e

ou

tpa

tie

nt d

ep

art

me

nt o

f a

te

rtia

ry le

ve

l h

osp

ita

l in

th

e

Ph

ilip

pin

es (

PJC

D v

ol 1

9 #

1)

25

.Asso

cia

tio

n o

f S

eru

m U

ric A

cid

Le

ve

ls a

nd

Ou

tco

me

s o

f P

atie

nts

with

Chro

nic

Ob

str

uctive

Pu

lmo

na

ry D

ise

ase

: A

Pro

sp

ective

Coh

ort

Stu

dy

(PJC

D v

ol 1

8 #

1)

26

.Co

rre

latio

n o

f F

ractio

na

l Exh

ale

d N

itri

c O

xid

e

Le

ve

l w

ith

Se

ve

rity

of C

hro

nic

Ob

str

uctive

Pu

lmo

na

ry

Dis

ea

se

(P

JC

D v

ol 1

8 #

1)

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Philipp J Chest Dis 201833

N

20

3

89

59

80

25

2

13

5

40

8

11

PO

PU

LA

TIO

N

AE

CO

PD

pa

tie

nts

se

en

in

VM

MC

ER

CO

PD

pa

tie

nts

CO

PD

& b

ron

ch

iecta

sis

pa

tie

nts

CO

PD

pa

tie

nts

in

PH

C

Asth

ma

pa

tie

nt in

LC

P c

linic

CO

PD

pa

tie

nts

CO

PD

pa

tie

nts

se

en

at L

CP

OP

D t

akin

g IC

S/L

AB

A

AE

CO

PD

pa

tie

nts

fro

m M

arc

h

20

14

-Ju

n 2

01

5

pa

tie

nts

wh

o u

nd

erw

en

t C

P

exe

rcis

e te

st p

rio

r to

su

rge

ry

wh

ere

in (

Ja

nu

ary

20

13

to

Ap

ril

20

17

at

SL

MC

-QC

; A

pri

l 2

01

5

to A

pri

l 2

01

7 a

t S

LM

C-G

C

SP

EC

IFIC

Pro

sp

ective

co

ho

rt

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

cro

ss-

se

ctio

na

l

Retr

osp

ective

Retr

osp

ective

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

Ch

ron

ic

Air

wa

y

Dis

ea

se

Chro

nic

Air

wa

y

Dis

ea

se

TIT

LE

(R

efe

ren

ce

)

27

.Va

lida

tio

n o

f th

e O

tta

wa

ris

k s

ca

le in

id

en

tify

ing

CO

PD

in

exa

ce

rba

tio

n p

atie

nts

se

en

in

th

e

em

erg

en

cy d

ep

art

me

nt a

t ri

sk o

f se

rio

us a

dve

rse

eve

nt (P

JC

D v

ol 1

9 #

1)

28

.Blo

od

Eo

sin

op

hili

a a

s P

red

icto

r fo

r P

atie

nt

Ou

tco

me

s in

Ch

ron

ic O

bstr

uctive

Pu

lmo

na

ry D

ise

ase

(PJC

D v

ol 1

8 #

1)

29

.Th

e a

ccu

racy o

f B

ron

ko

Te

st in

de

tectin

g b

acte

ria

l

infe

ctio

n in

pa

tie

nts

with

ch

ron

ic lu

ng

dis

ea

se

s (

PJC

D

vo

l 1

7 #

2)

30

.Th

e a

sso

cia

tion

be

twe

en

th

e le

ve

l o

f C

OP

D

se

ve

rity

an

d h

yp

eri

nfla

tio

n (

PJC

D v

ol 1

7 #

2)

31

.Ph

en

oty

pin

g o

f A

du

lt P

atie

nts

with

Bro

nch

ial

Asth

ma

at th

e L

un

g C

en

ter

of th

e P

hili

pp

ine

s O

PD

Asth

ma

Clin

ic: A

6-m

on

th P

ilot S

tud

y (

PJC

D v

ol 1

7

#4

)

32

.Pre

va

len

ce

of d

ep

ressio

n a

mo

ng

CO

PD

pa

tie

nts

in V

ete

ran

s M

em

ori

al M

ed

ica

l C

en

ter

(PJC

D v

ol 1

7

#2

)

33

.Scre

en

ing

fo

r O

ste

op

oro

sis

in M

ale

Ch

ron

ic

Ob

str

uctive

Pu

lmo

na

ry D

ise

ase

Pa

tie

nts

on

Lo

ng

-

term

IC

S U

se

vs N

on

-IC

S U

se

rs a

t th

e O

PD

of

the

Lu

ng

Cen

ter

of

the

Ph

ilip

pin

es (

PJC

D V

ol 1

9 #

1 J

an

-

Ma

r 2

01

8)

34

.Utilit

y o

f D

EC

AF

sco

re in

Hosp

ita

lize

d P

atie

nts

with

CO

PD

in

Acu

te E

xa

ce

rba

tio

n (

PJC

D v

ol 1

8 #

1)

35

.Re

latio

nship

of

pre

-op

era

tive

ca

rdio

pu

lmo

na

ry

exe

rcis

e te

stin

g w

ith

in

-ho

sp

ita

l ou

tco

me

s a

nd

le

ng

th

of sta

y o

f p

atie

nts

wh

o u

nd

erw

en

t m

ajo

r su

rge

ry in

a

tert

iary

ho

sp

ita

l in

th

e P

hili

pp

ine

s: A

de

scri

ptive

ca

se

se

rie

s s

tud

y (

PJC

D v

ol 1

9 #

1)

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Vol. 19 | Issue 03 | September 2018 34

N

20

4

43

10

7

39

27

10

0

71

9

PO

PU

LA

TIO

N

Dia

gn

ose

d C

OP

D p

atie

nts

in

UP

-PG

H,

UP

HD

MC

, Q

MM

C

Ad

ult p

atie

nts

ad

mitte

d a

t th

e

cri

tica

l ca

re u

nits in

SL

MC

Ad

ult p

atie

nts

ad

mitte

d in

IC

U

ICU

pa

tie

nts

in V

ete

rna

ns

Hosp

ita

l w

ith

de

liriu

m

AR

DS

Pa

tie

nts

in

US

T

Ho

sp

ita

l fr

om

Ja

n 2

01

2-

De

c

20

15

UP

PG

H p

atie

nts

with

SV

CO

Ad

ult p

atie

nts

se

en

at

the

LC

P

OS

A p

atie

nts

se

en

in

SL

MC

Sle

ep

Ce

nte

r w

ith

Be

rlin

Fle

mo

n a

nd

SL

MC

OS

AC

S

qu

estio

nn

aire

SP

EC

IFIC

Su

rve

y

Cro

ss-

se

ctio

na

l

Cro

ss-

se

ctio

na

l

Pro

sp

ective

Re

tro

sp

ective

Retr

osp

ective

Re

tro

sp

ective

Retr

osp

ective

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Descri

ptive

Descri

ptive

Descri

ptive

De

scri

ptive

Descri

ptive

De

scri

ptive

Descri

ptive

CL

US

TE

R

Chro

nic

Air

wa

y

Dis

ea

se

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Ca

re/V

asc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Ca

re/V

asc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

TIT

LE

(R

efe

ren

ce

)

36

.Pre

va

len

ce

of A

nxie

ty a

nd

Dep

ressio

n a

mo

ng

Fili

pin

o P

atie

nts

with

Ch

ron

ic O

bstr

uctive

Pu

lmo

na

ry

Dis

ea

se

: A

Mu

lti-

Cen

ter

Stu

dy (

PJIM

Vo

l 5

3 #

1)

37

.De

term

ina

tio

n o

f th

e e

nd

otr

ach

ea

l cu

ff p

ressu

re

tim

e-d

eca

y u

sin

g a

co

ntin

uo

us p

ressu

re m

on

ito

rin

g

de

vic

e (

PJC

D V

ol 1

6 #

1, Ja

n-M

ar

20

15

)

38

.Pre

va

len

ce

of d

elir

ium

in

pa

tie

nts

ad

mitte

d a

t

inte

nsiv

e c

are

un

its o

f P

GH

(P

JC

D V

ol 1

6 #

3, Ju

l-

Se

pt 2

01

5)

39

.Ne

uro

co

gn

itiv

e o

utc

om

e o

f p

atie

nts

with

de

liriu

m

in th

e in

ten

siv

e c

are

un

its a

t a

te

rtia

ry g

ove

rnm

en

t

ho

sp

ita

l (P

JC

D v

ol 1

8 #

2)

40

.Oxyg

en

Sa

tura

tio

n In

de

x a

s a

Su

rro

ga

te o

f

Pa

O2

/FiO

2 R

atio

in

Acu

te R

esp

ira

tory

Dis

tre

ss

Syn

dro

me

(P

JC

D v

ol 1

8 #

2 )

41

.Tre

atm

en

t o

utc

om

es o

f p

atie

nts

with

SV

C

syn

dro

me

wh

o r

ece

ive

d h

igh

-do

se

RT

at

UP

PG

H

fro

m 2

00

9-2

01

1 (

Acta

Me

dic

a P

hili

pp

ina

Vo

l 4

7 #

3,

20

13

)

42

.Th

ree

-ye

ar

revie

w o

f p

atie

nts

dia

gn

ose

d w

ith

Ob

str

uctive

Sle

ep

Ap

ne

a in

th

e L

CP

(P

JC

M V

ol 1

6

#2

, A

pri

l-Ju

ne

20

15

)

43

.Dia

gn

ostic A

ccu

racy o

f B

erl

in,

Fle

mo

ns

Sle

ep

Ap

ne

a C

linic

al S

co

re a

nd

St.

Lu

ke

’s M

ed

ica

l C

en

ter–

Ob

str

uctive

Sle

ep

Ap

ne

a C

linic

al S

co

re

Qu

estio

nn

air

es fo

r S

cre

en

ing

Ob

str

uctive

Sle

ep

Ap

ne

a in

Fili

pin

o P

atie

nts

(P

JC

D V

ol 1

8 #

4 O

ct-

Dec

20

17

)

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Philipp J Chest Dis 201835

N 84

56

45

23

5

20

(ctr

l)

vs 5

5

(in

terv

en

tio

n)

41

13

3

PO

PU

LA

TIO

N

ICU

pa

tie

nts

re

ferr

ed

an

d n

ot

refe

rre

d to

clin

ica

lnu

trtio

n

Me

dic

al re

sid

en

ts in

PG

H

Nurs

es w

ith

in

tub

ate

d p

atie

nts

in IC

U o

f M

MC

Ju

n 2

01

6-D

ec

20

16

intu

ba

ted

pa

tie

nts

ad

mitte

d a

t

the

IC

U

Intu

ba

ted

pa

tie

nts

at th

e IC

U o

f

TM

C

Pa

tie

nts

of sp

ecia

l ca

re u

nits in

Cho

ng

Hu

a H

osp

ita

l

Ad

ult p

atie

nts

at th

e C

EN

ICU

an

d M

ICU

LC

P n

urs

es

SP

EC

IFIC

Retr

osp

ective

co

ho

rt

Su

rve

y

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

co

ho

rt

Coh

ort

Cro

ss-

se

ctio

na

l

ST

UD

Y

DE

SIG

N

Descri

ptive

Descri

ptive

Descri

ptive

Inte

rve

ntio

na

l

Inte

rve

ntio

na

l

Inte

rve

ntio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

TIT

LE

(R

efe

ren

ce

)

44

.Clin

ica

l Ou

tco

me

s o

f M

ech

an

ica

lly V

en

tila

ted

Pa

tie

nts

in

th

e In

ten

siv

e C

are

Unit R

efe

rre

d to

Clin

ica

l Nutr

itio

n S

erv

ice

s (

PJC

D v

ol 1

8 #

1)

45

.A s

urv

ey o

f p

ractice

pa

tte

rns o

f m

ed

ica

l re

sid

en

ts

on

th

e u

se

of n

on

-in

va

siv

e v

en

tila

tio

n a

t P

GH

(P

JC

D

Vo

l 1

6 #

3, Ju

l-S

ep

t 2

01

5)

46

.Ad

he

ren

ce

, E

na

ble

rs a

nd

Ba

rrie

rs to

th

e

Imp

lem

en

tatio

n o

f th

e V

en

tila

tor-

Asso

cia

ted

Pn

eu

mo

nia

Bu

nd

le in

th

e In

ten

siv

e C

are

Un

its a

t th

e

Ma

ka

ti M

ed

ica

l C

en

ter

(PJC

D v

ol 1

9 #

1)

47

.Th

e e

ffe

ct o

f w

he

y p

rote

in s

up

ple

me

nta

tio

n o

n

du

ratio

n o

f m

ech

an

ical v

en

tila

tio

n

48

.Th

e A

sso

cia

tio

n b

etw

ee

n Im

ple

me

nta

tion

of

Bu

nd

les o

f C

are

an

d P

ossib

le V

en

tila

tor

Asso

cia

ted

Pn

eu

mo

nia

Am

on

g M

ech

an

ica

lly V

en

tila

ted

Pa

tie

nts

in th

e In

ten

siv

e C

are

Un

it: A

Qu

asi-

Exp

eri

me

nta

l

Stu

dy (

PJC

D v

ol 1

8 #

1)

49

.A c

om

pa

riso

n o

f th

e c

linic

al o

utc

om

e o

f th

e n

ew

en

tera

l fe

ed

ing

pro

toco

l ve

rsu

s tra

ditio

na

l en

tera

l

fee

din

g a

mo

ng

cri

tica

lly-i

ll p

atie

nts

ad

mitte

d a

t C

ho

ng

Hua

Hosp

ita

l S

pe

cia

l C

are

Unit (

PJC

D V

ol 1

6 #

3, Ju

l-

Se

pt 2

01

5)

50

.Obse

rva

tio

na

l stu

dy o

n t

he

cu

rre

nt w

ea

nin

g

pra

ctice

s in

th

e c

en

tra

l in

ten

siv

e c

are

an

d m

ed

ica

l

inte

nsiv

e c

are

un

its o

f th

e P

GH

(P

JC

D V

ol 1

6 #

3, Ju

l-

Se

pt 2

01

5)

51

.Pre

va

len

ce

an

d c

on

se

qu

ence

s o

f sh

ift w

ork

dis

ord

er

am

on

g n

urs

es a

t L

CP

(P

JC

M V

ol 1

6 #

2,

Ap

ril-

Ju

ne

20

15

)

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Vol. 19 | Issue 03 | September 2018 36

N

15

6

36

20

29

0

PO

PU

LA

TIO

N

Bu

s d

rive

rs o

f co

mp

an

ies w

ith

sta

tio

ns in

QC

20

stu

die

s

Nurs

es w

ith

in

tub

ate

d p

atie

nts

in IC

U o

f M

MC

Ju

n 2

01

6-D

ec

20

16

pa

tie

nts

ad

mitte

d in

MIC

U o

f

PG

H

cri

tica

lly il

l in

tub

ate

d p

atie

nts

in

SL

MC

an

d d

ete

rmin

ation

of

RS

Bi

intu

ba

ted

pa

tie

nts

ad

mitte

d a

t

the

IC

U o

f P

HC

SP

EC

IFIC

Cro

ss-

se

ctio

na

l

Me

ta-a

na

lysis

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

co

ho

rt

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Ca

re/V

asc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

TIT

LE

(R

efe

ren

ce

)

52

.Pre

va

len

ce

of O

SA

sym

pto

ms a

nd

exce

ssiv

e

da

ytim

e s

lee

pin

ess a

mo

ng

co

mm

erc

ial l

on

g-d

ista

nce

bu

s d

rive

rs in

th

e P

hili

pp

ine

s (

PJC

M V

ol 1

6 #

2, A

pri

l-

Ju

ne

20

15

)

53

.No

n-i

nva

siv

e V

en

tila

tio

n v

ers

us C

on

ve

ntio

na

l

Oxyg

en

Th

era

py in

Im

mu

no

-co

mpro

mis

ed

Pa

tie

nts

: A

Me

ta-a

na

lysis

(P

JC

D v

ol 1

8 #

1)

54

.Th

e A

sso

cia

tio

n b

etw

ee

n Im

ple

me

nta

tion

of

Bu

nd

les o

f C

are

an

d P

ossib

le V

en

tila

tor

Asso

cia

ted

Pn

eu

mo

nia

Am

on

g M

ech

an

ica

lly V

en

tila

ted

Pa

tie

nts

in th

e In

ten

siv

e C

are

Unit: A

Qu

asi-

Exp

eri

me

nta

l

Stu

dy (

PJC

D v

ol 1

8 #

1)

55

.A P

relim

ina

ry S

tud

y o

n th

e N

utr

itio

na

l In

take

an

d

Clin

ica

l Ou

tco

me

s o

f P

atie

nts

Ad

mitte

d a

t th

e M

ed

ica

l

Inte

nsiv

e C

are

Unit (

PJC

D v

ol 1

8 #

1)

56

.De

ve

lop

me

nt o

f a

va

lida

ted

qu

estio

nn

air

e to

de

term

ine

th

e K

no

wle

dg

e, A

ttitu

de

an

d P

ractice

s o

f

Inte

rnis

ts in

de

term

inin

g p

atie

nt’s r

ea

din

ess fo

r

we

an

ing

an

d d

isco

ntin

ua

tio

n fro

m v

en

tila

tory

su

pp

ort

57

.A C

om

pa

rative

Stu

dy o

n th

e D

iap

hra

gm

Mu

scle

Th

ickn

ess a

nd

Rap

id S

ha

llow

Bre

ath

ing

In

de

x (

RS

BI)

as a

pre

dic

tor

for

su

cce

ssfu

l extu

ba

tio

n a

mo

ng

cri

tica

lly il

l a

du

lt p

atie

nts

(P

JC

D v

ol 1

9 #

1 J

an

-Ma

r

20

18

)

58

.Accu

racy o

f G

as E

xch

an

ge

Me

asu

rem

en

ts a

s

Pre

dic

tors

Of

Ea

rly S

ucce

ssfu

l We

anin

g A

mo

ng

IC

U

Pa

tie

nts

of P

hili

pp

ine

Hea

rt C

en

ter:

A P

rosp

ective

Coh

ort

Stu

dy (

PJC

D v

ol 1

9 #

1)

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Philipp J Chest Dis 201837

N

14

42

52

/48

52

76

17

1

20

2

52

PO

PU

LA

TIO

N

Me

ch

an

ica

ll ve

ntila

ted

pa

tie

nts

in M

DH

(V

AP

bu

nd

le

gro

up

Ap

ril-

Se

p 2

01

6)

&

ba

se

line

gro

up

(S

ep

20

14

-Fe

b

20

15

)

pa

tie

nts

ad

mitte

d in

US

TH

IC

U

(De

c 2

01

3-M

ar

20

14

)

Pa

tie

nts

at U

ST

H

PS

G s

tud

ies th

rou

gh

Resp

ica

re

Pa

tie

nts

se

en

at th

e S

lee

p L

ab

of L

CP

fem

ale

pa

tie

nts

in S

LM

C w

ith

pri

ma

ry lu

ng

ca

SP

EC

IFIC

Pro

sp

ective

co

ho

rt

Case

co

ntr

ol

Retr

osp

ective

Retr

osp

ective

Retr

osp

ective

Su

rve

y

Cro

ss-

se

ctio

na

l

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Descri

ptive

CL

US

TE

R

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

Cri

tica

l

Care

/Va

sc

ula

r/S

lee

p

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

TIT

LE

(R

efe

ren

ce

)

59

.Co

nco

rda

nce

of In

cid

en

ce

of P

osto

pe

rative

Pu

lmo

na

ry C

om

plic

atio

ns w

ith

Pre

dic

ted

Pro

ba

bili

ties

Usin

g M

ultifa

cto

ria

l R

isk In

de

x f

or

Po

sto

pe

rative

Pn

eu

mo

nia

an

d R

esp

ira

tory

Fa

ilure

at th

e V

ete

ran

s

Me

mo

ria

l M

ed

ica

l C

en

ter

60

.Th

e E

ffic

acy o

f th

e V

en

tila

tor

Bu

nd

le in

Pre

ve

ntin

g

Ve

ntila

tor-

Associa

ted P

ne

um

on

ia a

mo

ng

IC

U

Pa

tie

nts

in

th

e M

an

ila D

octo

rs H

osp

ita

l (P

JC

D v

ol 1

9

#1

)

61

.Asse

ssm

en

t o

f ri

sk fo

r V

TE

an

d V

TE

pro

ph

yla

xis

ba

se

d o

n th

e T

hro

mb

osis

Ris

k A

sse

ssm

en

t F

orm

fo

r

Me

dic

al a

nd

Su

rgic

al P

atie

nts

am

on

g IC

U p

atie

nt

(PJC

D v

ol 1

7 #

2)

62

.Pre

dic

tors

of

failu

re a

mo

ng

pa

tie

nts

giv

en

no

n-

inva

siv

e m

ech

an

ica

l ve

ntila

tio

n a

t th

e U

ST

Hosp

ita

l

(PJC

D V

ol 1

6 #

1, Ja

n-M

ar

20

15

)

63

.Ad

juste

d n

eck c

ircu

mfe

rence

sco

re, S

TO

P B

AN

G,

an

d B

erl

in q

ue

stio

nn

air

e a

s s

cre

en

ing

to

ols

fo

r O

SA

(PJC

M V

ol 1

6 #

2, A

pri

l-Ju

ne

20

15

)

64

.A s

urv

ey o

f kn

ow

led

ge

, a

ttitu

de

s a

nd

pra

ctice

s o

f

se

da

tio

n a

nd

an

alg

esia

am

on

g m

ed

ica

l re

sid

en

ts a

nd

pu

lmo

na

ry fe

llow

s in

tra

inin

g a

t th

e U

niv

ers

ity o

f th

e

Ph

ilip

pin

es G

en

era

l H

osp

ita

l (P

JC

D v

ol 1

8 #

1)

65

.De

ve

lop

me

nt a

nd

va

lida

tio

n o

f a

pre

dic

tive

fo

rmu

la

for

op

tim

al C

PA

P le

ve

l in

Fili

pin

o p

atie

nts

with

OS

A

se

en

in

LC

P (

PJC

D V

ol 1

6 #

2, A

pri

l-Ju

ne

20

15

)

66

.Clin

ica

l Pro

file

s a

nd

Su

rviv

al o

f F

em

ale

Pa

tie

nts

Dia

gn

ose

d w

ith

Pri

ma

ry L

un

g C

an

ce

r R

eg

iste

red

at

the

Lu

ng

Can

ce

r R

eg

istr

y o

f S

t. L

uke

’s M

ed

ica

l

Cen

ter

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Vol. 19 | Issue 03 | September 2018 38

N

31

2

26

25

1

77

00

98

13

33

11

2

PO

PU

LA

TIO

N

Lu

ng

Ca

nce

r p

atie

nts

in L

CP

ad

mitte

d fo

r p

ne

um

on

ia

EB

US

pro

ce

du

re d

on

e in

TM

C

Ja

n 2

01

5-D

ec 2

01

5)

Pa

tie

nts

ad

mitte

d a

t a

te

rtia

ry

ho

sp

ita

l (2

01

1-2

01

3)

with

a

his

tolo

gic

/ cyto

log

ic d

iag

no

sis

of p

rim

ary

lu

ng

ca

nce

r

Fili

pin

o a

du

lts in

17

re

gio

ns

pa

tie

nts

in V

MM

C w

ith

ma

lign

an

t p

leu

ral e

ffu

sio

n

10

stu

die

s th

at in

vo

lve

pa

tie

nts

with

in

dw

elli

ng

ca

the

ters

Pa

tie

nts

wh

o u

nd

erw

en

t

bro

nch

oscop

u s

usp

ecte

d fo

r

ma

lign

an

cy

SP

EC

IFIC

Retr

osp

ective

Retr

osp

ective

Retr

osp

ective

Su

rve

y

Am

bis

pe

ctive

co

ho

rt

Me

ta-a

na

lysis

Pro

sp

ective

Pro

sp

ective

cro

ss-

se

ctio

na

l

ST

UD

Y

DE

SIG

N

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

TIT

LE

(R

efe

ren

ce

)

67

.Clin

ica

l Pro

file

an

d O

utc

om

e o

f L

un

g C

an

ce

r

Pa

tie

nts

with

Pn

eu

mo

nia

Ad

mitte

d a

t L

un

g C

en

ter

of

the

Ph

ilip

pin

es: A

5-y

ea

r R

etr

osp

ective

Stu

dy (

PJC

D

vo

l 1

8 #

3)

68

.En

do

bro

nchia

l Ultra

so

un

d-G

uid

ed T

ran

sb

ron

ch

ial

Nee

dle

Asp

ira

tio

n in

th

e P

hili

pp

ine

s: A

Pre

limin

ary

Retr

osp

ective

Coh

ort

Stu

dy o

n D

iag

no

stic

Pe

rfo

rma

nce

(P

JC

D v

ol 1

7 #

3)

69

.A R

etr

osp

ective

Stu

dy C

om

pa

rin

g Y

ou

ng

an

d O

ld

Pa

tie

nts

Dia

gn

ose

d w

ith

Pri

ma

ry L

un

g C

an

ce

r (P

JC

D

vo

l 1

8 #

2)

70

.Sm

okin

g b

urd

en

in

th

e P

hili

pp

ine

s (

Acta

Me

dic

a

Ph

ilip

pin

a V

ol 4

7 #

3, 2

01

3)

71

.LE

NT

Pro

gn

ostic S

co

re in

Ma

lign

an

t P

leu

ral

Eff

usio

n a

t V

ete

ran

s M

em

ori

al M

ed

ica

l C

en

ter

(PJC

D

vo

l 1

8 #

1)

72

.A M

eta

-an

aly

sis

on

In

dw

elli

ng

Ple

ura

l C

ath

ete

rs

vs P

leu

rod

esis

in th

e M

an

ag

em

en

t o

f M

alig

na

nt

Ple

ura

l E

ffu

sio

ns: A

Mo

de

rn D

ilem

ma

(P

JC

D v

ol 1

9

#1

)

73

.Na

tio

na

l Sm

okin

g P

reva

len

ce

Stu

dy (

PJIM

vo

l 5

1

#1

)

74

.Co

mp

ara

bili

ty o

f A

uto

ma

ted

Qu

an

tita

tive

Im

ag

e

Cyto

me

try (

Cle

arC

yte

TM

) R

esu

lts o

f B

ron

ch

ial

Wash

ing

s w

ith

Ma

nu

al C

yto

log

y a

nd

His

top

ath

olo

gy

in th

e D

iag

no

sis

of L

un

g C

an

ce

r (P

JC

D v

ol 1

9 #

1)

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Philipp J Chest Dis 201839

N 88

10

0

21

2

15

9

17

96

16

1

50

8

PO

PU

LA

TIO

N

Case

re

vie

w o

f p

atie

nts

with

MP

E in

CG

H

pa

tie

nt in

VM

MS

with

ma

lign

an

t p

leu

ral e

ffu

sio

n

UP

Ma

nila

stu

de

nts

ag

ed

18

-

24

Su

sp

ecte

d M

DR

TB

ca

se

s

sta

rte

d o

n S

TR

at th

e L

CP

MD

RT

B p

atie

nts

All

pa

tie

nts

co

mp

lete

d C

atI

tre

atm

en

t a

t L

CP

Ad

ult p

atie

nts

in V

MM

C w

ith

co

ug

h o

f le

ss th

an

2 w

ee

ks

SS

P a

nd

Tb

pa

tie

nts

ad

mitte

d

in L

CP

ja

n 2

00

4 to

De

c 2

01

3

SP

EC

IFIC

Retr

osp

ective

Retr

osp

ective

Am

bis

pe

ctive

co

ho

rt

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

cro

ss-

se

ctio

na

l

Retr

osp

ective

co

ho

rt

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

CL

US

TE

R

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

ILD

/Ma

lign

an

cy/S

mo

ki

ng

/Air

Po

llutio

n

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

TIT

LE

(R

efe

ren

ce

)

75

.Pro

gn

ostic u

tilit

y o

f th

e L

EN

T S

co

re in

Pre

dic

tin

g

Su

rviv

al a

mo

ng

Pa

tie

nts

with

Ma

lign

an

t P

leu

ral

Eff

usio

n a

dm

itte

d a

t th

e C

hin

ese

Ge

ne

ral H

osp

ita

l

an

d M

ed

ica

l C

en

ter:

A C

oh

ort

Stu

dy (

PJC

D v

ol 1

9

#1

)

76

.Va

lidity o

f th

e L

EN

T P

rog

no

stic S

co

re fo

r

Pre

dic

tin

g S

urv

iva

l in

Ma

lign

an

t P

leu

ral E

ffu

sio

n

(PJC

D v

ol 1

8 #

1)

77

.Eva

lua

tio

n fo

r cig

are

tte

s a

mo

ng

UP

Ma

nila

stu

de

nts

th

rou

gh

sta

ted

pre

fere

nce

me

tho

ds (

Acta

Me

dic

a P

hili

pp

ina

Vo

l 4

8 #

3, 2

01

4)

78

.Tre

atm

en

t o

utc

om

e o

f p

atie

nts

pre

vio

usly

sta

rte

d

on

sta

nd

ard

ize

d tre

atm

en

t re

gim

en

fo

r su

sp

ecte

d

MD

R-T

B a

t th

e L

CP

: P

MD

T (

PJC

D V

ol 1

6 #

4, O

ct-

Dec 2

01

5)

79

.Ou

tco

me

s o

f M

ulti D

rug

Re

sis

tan

t T

ub

erc

ulo

sis

Con

tacts

wh

o r

ece

ive

d C

ate

go

ry I T

rea

tme

nt fo

r

Clin

ica

lly D

iag

no

se

d P

ulm

on

ary

Tu

be

rcu

losis

un

de

r

DO

TS

80

.Pre

va

len

ce

of p

ulm

on

ary

im

pa

irm

en

t a

fte

r

tre

atm

en

t o

f p

ulm

on

ary

tu

be

rcu

losis

am

on

g p

atie

nts

tre

ate

d a

t th

e L

CP

81

.Pre

dic

tio

n o

f P

ne

um

on

ia B

ase

d o

n S

ign

s a

nd

Sym

pto

ms in

Pa

tie

nts

Pre

se

ntin

g w

ith

Co

ug

h a

t th

e

Ve

tera

ns M

em

ori

al M

ed

ica

l C

en

ter

(PJC

D v

ol 1

8 #

2)

82

.Ris

k F

acto

rs fo

r D

eve

lop

me

nt o

f S

eco

nd

ary

Sp

on

tan

eo

us P

ne

um

oth

ora

x in

Pa

tie

nts

with

Pu

lmo

na

ry T

ub

erc

ulo

sis

Ad

mitte

d to

th

e L

un

g C

en

ter

of th

e P

hili

pp

ine

s: A

10

-ye

ar

Exp

eri

en

ce

(P

JC

D v

ol

18

#1

)

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Vol. 19 | Issue 03 | September 2018 40

N

12

4

63

18

4

83

15

3

15

3

16

4

PO

PU

LA

TIO

N

ICU

pa

tie

nts

in C

ho

ng

Hu

a

Hosp

ita

l

Lu

ng

Ca

nce

r p

atie

nts

in

Ve

tera

ns H

osp

ita

l with

PT

B

dia

gn

osis

PT

B p

atie

nts

re

gis

tere

d u

nd

er

DO

TS

in

Bin

an

an

d C

ab

uya

o,

La

gu

na

pa

tie

nts

dia

gn

ose

d w

ith

HIV

with

pu

lmo

na

ry p

rese

nta

tio

n

fro

m ja

n 2

00

0 to

Se

p 2

01

5

ne

ga

tive

sm

ea

r P

TB

re

ferr

ed

to U

ST

H T

BD

C

Neg

ative

-sm

ea

r P

TB

pa

tie

nts

refe

rre

d to

US

TH

-TB

DC

fro

m

Ja

n 2

01

4to

De

c 2

01

4

Ad

mitte

d p

atie

nts

at th

e L

CP

SP

EC

IFIC

Retr

osp

ective

Retr

osp

ective

cro

ss-

se

ctio

na

l

Su

rve

y

Cro

ss-

se

ctio

na

l

Retr

osp

ective

Retr

osp

ective

Retr

osp

ective

ST

UD

Y

DE

SIG

N

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

Descri

ptive

CL

US

TE

R

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

TIT

LE

(R

efe

ren

ce

)

83

.Co

rre

latio

n o

f e

nd

otr

ach

ea

l asp

ira

te G

ram

sta

in

an

d fin

al cu

ltu

re r

esu

lts in

IC

U p

atie

nts

in a

te

rtia

ry

ho

sp

ita

l in

Ceb

u C

ity:

A r

etr

osp

ective

stu

dy (P

JC

D

Vo

l 1

6 #

4, O

ct-

Dec 2

01

5)

84

.Pre

va

len

ce

of tu

be

rcu

losis

infe

ctio

n in

ca

nce

r

pa

tie

nts

at

Ve

tera

ns M

em

ori

al M

ed

ica

l C

en

ter

(PJC

D

vo

l 1

8 #

2)

85

.So

cio

-co

gn

itiv

e fa

cto

rs a

nd

pe

rce

ive

d b

arr

iers

:

Th

eir

in

flu

en

ce

on

th

e p

atie

nt's

ad

he

ren

ce

to

PT

B

tre

atm

en

t (A

cta

Me

dic

aP

hili

pp

ina

Vo

l 4

8 #

3, 2

01

4)

86

.Asse

ssm

en

t o

f th

e U

tiliz

atio

n o

f G

en

e X

pe

rt

MT

B/R

IF in

Ph

ilip

pin

e T

ub

erc

ulo

sis

So

cie

ty, In

c

87

.Clin

ica

l Corr

ela

tio

n o

f A

bso

lute

To

tal L

ym

ph

ocyte

an

d C

D4

T-L

ym

ph

ocyte

Co

un

t w

ith

Pu

lmo

na

ry

Com

plic

atio

ns o

f H

um

an

Im

mu

no

de

ficie

ncy V

iru

s

(HIV

) S

ero

po

sitiv

e P

atie

nts

Se

en

at th

e L

un

g C

en

ter

of th

e P

hili

pp

ine

s (

PJC

D v

ol 1

7 #

4)

88

.Pe

rfo

rma

nce o

f T

B D

iag

no

stic C

om

mitte

e in

Cert

ifyin

g D

ise

ase

Activity o

f S

me

ar

Neg

ative

Cate

go

ry II C

ase

s in

Dis

tric

t IV

of M

an

ila

89

.Tu

rna

rou

nd

Tim

e f

or

Sm

ea

r-n

eg

ative

Ca

teg

ory

I

Case

s to

In

itia

tio

n o

f T

rea

tme

nt in

Dis

tric

t IV

of

Ma

nila

fro

m J

an

ua

ry 2

01

4 to

Dece

mb

er

20

14

(P

JC

D v

ol 1

8

#2

)

90

.A 1

3-y

ea

r re

tro

sp

ective

stu

dy o

n c

linic

al p

rofile

an

d m

an

ag

em

ent o

f p

atie

nts

ad

mitte

d fo

r p

ulm

on

ary

asp

erg

illo

ma

(P

JC

D V

ol 1

6 #

4, O

ct-

Dec 2

01

5)

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Philipp J Chest Dis 201841

N

16

2

63

10

2

71

17

8

78

PO

PU

LA

TIO

N

Ad

mitte

d a

du

lt p

atie

nts

at

the

LC

P

pa

tie

nts

in L

CP

with

ple

ura

l

eff

usio

n,p

ost d

rain

ag

e

Ad

mitte

d p

atie

nts

at th

e L

CP

PT

B p

atie

nts

un

de

rgo

ing

tre

atm

en

fo

r C

at II

HIV

pa

tie

nts

co

-in

fecte

d w

ith

TB

en

rolle

d a

t th

e S

AG

IP U

nit

fro

m J

an

-De

c 2

01

4

Pa

tie

nts

ad

mitte

d a

t th

e w

ard

of P

GH

ICU

pa

tie

nts

in C

ho

ng

Hu

a

Hosp

ita

l

SP

EC

IFIC

Retr

osp

ective

Cro

ss-

se

ctio

na

l

Cro

ss-

se

ctio

na

l

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

Pro

sp

ective

ST

UD

Y

DE

SIG

N

Descri

ptive

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

CL

US

TE

R

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

TIT

LE

(R

efe

ren

ce

)

91

.A r

etr

osp

ective

stu

dy o

n th

e c

linic

al p

rofile

of

pa

tie

nts

with

se

co

nd

ary

sp

on

tan

eo

us p

ne

um

oth

ora

x,

with

co

exis

tin

g p

ulm

on

ary

tu

be

rcu

losis

at th

e L

CP

fro

m J

an

ua

ry 2

00

8 to

Dece

mb

er

20

12

(P

JC

D V

ol 1

6

#4

, O

ct-

Dec 2

01

5)

92

.Va

lidity o

f P

leu

ral F

luid

Cho

leste

rol in

Diffe

ren

tia

tin

g E

xu

da

tive

fro

m T

ran

su

da

tive

Ple

ura

l

Eff

usio

ns o

f P

leu

ral F

luid

Cho

leste

rol i

n

Diffe

ren

tia

tin

g E

xu

da

tive

fro

m T

ran

su

da

tive

Ple

ura

l

Eff

usio

ns (

PJC

D v

ol 1

8 #

1)

93

.Co

mp

ari

so

n o

f p

rese

psin

an

d p

roca

lcito

nin

as

bio

ma

rke

rs in

th

e d

iag

no

sis

of

se

psis

(P

JC

D V

ol 1

6

#4

, O

ct-

Dec 2

01

5)

94

.Co

mp

ara

tive

An

aly

sis

of G

en

eX

pe

rt M

TB

/RIF

Assa

y T

estin

g w

ith

MT

B C

ultu

re A

mo

ng

PT

B

Cate

go

ry II–

Tre

ate

d P

atie

nts

(P

JC

D v

ol 1

7 #

2)

95

.Ad

he

ren

ce

to

th

e N

atio

na

l T

ub

erc

ulo

sis

Co

ntr

ol

Pro

gra

m G

uid

elin

es 2

01

3 a

nd

Ou

tco

me

of T

rea

tme

nt

on

Pe

op

le L

ivin

g W

ith

HIV

Co

-In

fecte

d w

ith

Tu

be

rcu

losis

En

rolle

d in

th

e P

hili

pp

ine

Ge

ne

ral

Hosp

ita

l T

rea

tme

nt H

ub

(S

AG

IP)

(PJC

D v

ol 1

8 #

1)

96

.Clin

ica

l pro

file

an

d o

utc

om

e o

f S

ten

otr

op

ho

mo

na

s

ma

lto

ph

ilia in

fectio

ns a

mo

ng

Ad

ult p

atie

nts

Ad

mitte

d

at th

e U

niv

ers

ity o

f S

an

to T

om

as H

osp

ita

l: A

Se

ve

n

ye

ar

Re

tro

sp

ective

Stu

dy

97

.Eva

lua

tin

g th

e u

tilit

y o

f th

e C

AP

-PIR

O s

co

rin

g

syste

m in

ad

ult p

atie

nts

with

se

ve

re c

om

mu

nity-

acq

uir

ed

pn

eu

mo

nia

at C

ho

ng

Hua

Hosp

ita

l (P

JC

D

Vo

l 1

6 #

1, Ja

n-M

ar

20

15

)

98

.Sa

fety

an

d e

ffic

acy o

f C

efp

iro

me

am

on

g F

ilip

ino

Pa

tie

nts

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Vol. 19 | Issue 03 | September 2018 42

N 27

10

98

60

52

27

PO

PU

LA

TIO

N

ad

ult T

B p

atie

nts

Ad

ult p

atie

nts

with

un

ilate

ral

ple

ura

l e

ffu

sio

n

ad

ult p

atie

nts

in

Ad

ult p

atie

nts

ad

mitte

d fo

r lu

ng

rese

ctio

n

SP

EC

IFIC

Pro

sp

ective

Pro

sp

ective

co

ho

rt

Retr

osp

ective

Retr

osp

ective

co

ho

rt

Retr

osp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

cro

ss-

se

ctio

na

l

Pro

sp

ective

co

ho

rt

ST

UD

Y

DE

SIG

N

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Ob

se

rva

tio

na

l

Descri

ptive

CL

US

TE

R

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Infe

ctio

us

Lu

ng

Dis

ea

se

s

Oth

ers

:

Pu

lmo

Reh

ab

Oth

ers

:

Nutr

itio

n

TIT

LE

(R

efe

ren

ce

)

99

.Th

e in

cid

en

ce

of M

yco

ba

cte

riu

m o

the

nth

an

Tu

be

rcu

losis

Iso

late

d in

sp

ecim

en

s S

usp

ecte

d o

f

Tu

be

rcu

losis

in a

Te

rtia

tyH

osp

ita

l in

th

e P

hili

pp

ine

s

10

0.S

cre

en

ing fo

r D

iab

ete

s M

elli

tus in

Pa

tie

nts

dia

gn

ose

d w

ith

Pu

lmo

na

ry T

ub

erc

ulo

sis

(P

JIM

vo

l 5

2

#4

)

10

1.F

irst L

ine

An

ti-t

ub

erc

ulo

sis

Dru

g R

esis

tan

ce

Pa

tte

rn in

Myco

ba

cte

riu

m tu

be

rcu

losis

iso

late

s a

t th

e

Univ

ers

ity o

f S

an

to T

om

as H

osp

ita

l fr

om

20

03

-20

13

10

2.I

mp

act o

f A

dh

ere

nce

to

th

e P

hili

pp

ine

Clin

ica

l

Pra

ctice

Gu

ide

line

s o

n th

e C

linic

al O

utc

om

es o

f

Pa

tie

nts

Ho

sp

ita

lize

d fo

r C

om

mu

nity-A

cq

uir

ed

Pn

eu

mo

nia

at th

e L

un

g C

en

ter

of th

e P

hili

pp

ine

s

(PJC

D v

ol 1

7 #

3)

10

3.V

alid

ity S

tud

y o

f G

en

e X

pe

rt M

TB

/RIF

Assa

y in

the

Dia

gn

osis

of T

ub

erc

ulo

us P

leu

ral E

ffu

sio

n a

mo

ng

Ad

ult a

tie

nts

at

the

Lu

ng

Cen

ter

of th

e P

hili

pp

ine

s

(PJC

D V

ol 1

8 #

4 O

ct-

Dec 2

01

7)

10

4.O

utc

om

e o

f P

atie

nts

Who

Und

erw

en

t

Pro

gra

mm

atic P

ulm

on

ary

Reh

ab

ilita

tion

Ve

rsu

s

Ince

ntive

Sp

iro

me

try A

lon

e A

fte

r L

un

g R

ese

ctive

Su

rge

ry: A

Pro

sp

ective

, O

bse

rva

tio

na

l, C

ross-

Se

ctio

na

l, P

ilot S

tud

y (

PJC

D v

ol 1

7 #

3)

10

5.P

re-o

pe

rative

Nutr

itio

na

l Asse

ssm

en

t in

Su

rgic

al

Lu

ng

Rese

ctio

n a

nd

Occu

rre

nce

of P

osto

pe

rative

Pu

lmo

na

ry C

om

plic

atio

n: A

Pro

sp

ective

Coh

ort

Stu

dy

(PJC

D v

ol 1

8 #

1)

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Philipp J Chest Dis 201843

Appendix II. Revised guidelines on research grant applications

I. PCCP GUIDELINES FOR COUNCIL INITIATED/SUPPORTED RESEARCHES

A. Grant Eligibility

• In order to avoid any implication of conflict of interest, no member of a grant review committee

may submit a grant application. Those committee members who are mentioned in an application

or have written a letter of support must excuse themselves from the deliberations.

• A grant recipient/winner shall not be allowed to apply for the same PCCP or industry sponsored

grant within a period of five years. Grant recipients may apply for a different grant.

B. Grant Application

• Submission by the grant applicant of a description of the project to be funded should be in

sufficient detail

• A written confirmation by the grant applicant to use grant funds solely for purposes of the project

described in the application and to return any unspent funds or any funds that are spent for an

improper purpose shall be submitted.

C. Receipt of Proposal

• As proposals are received, they will be added to a grant list with the following information: author,

PCCP council, title, primary reviewer, secondary reviewer.

• Proposals must contain the endorsement of the Council Chair with the approval of a majority its

members during one its meetings (50% of attendees plus one with the total number achieving a

quorum). Electronic approval through the internet or SMS are also acceptable alternatives.

• Proposals must be submitted for review by an Institutional Review Board (IRB) / Ethics

Committee.

• The Research Committee Chair will forward it to the Grants Unit where a primary and secondary

reviewer will be assigned to each grant.

• After proposals are received, PCCP staff will send the following information to each reviewer:

o Copy of the proposals assigned to them by the Research Committee Chair. A committee

member may request to see/review any of the proposals

o List of grants with review assignments

o Evaluation forms

o Memo from Research Committee Chair with instructions and deadlines

• The Research Committee will be given two weeks to review the assigned grants and submit the

evaluations to PCCP Office.

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Vol. 19 | Issue 03 | September 2018 44

D. Budgetary Allocations

• The budgetary requirements of the study proposal must be stated.

• A detailed allocation must be provided to support the total budget as proposed.

• The grants application must state the amount that it is seeking from the PCCP. A study of

national scope, may apply for a maximum of 300K. Research topics listed in the PCCP Research

agenda will be given priority.

• The approved amount will be at the discretion of the committee, with the Executive Board

granting final approval for disbursement.

• The total budgetary allocation will be released upon the approval of the Executive Board.

E. Grant Approval

• After a proposal is endorsed for funding, the Research Committee will submit their decision to the

Executive Board for approval.

• Upon approval, PCCP inform the council, through its respective Chair, of the Research

Committee’s decision. PCCP staff will also provide the proponents with the reviews and

comments to be answered by the proponents in two weeks.

• The letters should be mailed within a week of the Research Committee decision.

• The grant winner should be contacted to collect the information necessary for a check request, in

order to receive the grant money.

• A document from PCCP to be signed by the Principal Investigator and the Chair of the Research

Committee should outline the terms of the grant including target completion and progress report.

• Fifty percent of the approved budget should be released upon approval.

• An interim report within a year of approval must be made.

• The grant recipient will also be recognized at the PCCP Annual Convention Research

Presentation.

• The research results should be presented within a maximum of two years from funding.

• If the paper is mainly funded by PCCP then it reserves the right to publish the paper in its own

journal, unless it waives its rights.

• Works in progress must submit a progress report midway through the project, further tranches

maybe released based on the report

• Finished papers should be presented during the annual PCCP convention

• An acknowledgement of the PCCP support provided is expected with the publication of the study,

regardless of the amount of support, as part of disclosure and in recognition of the assistance.

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Philipp J Chest Dis 201845

F. Grant Extension

• Grant recipients, upon written request to the Chair of the Research Committee, shall be granted

an extension beyond the anticipated completion of the research of a maximum of one year

• If, after the extension expires, the research project is still not completed, any further extension of

time shall be decided by the PCCP Executive Board and the Chair of the Research Committee.

• A paper not finishing during the proscribed period of implementation must justify in writing or else

forfeit the remainder of the funding and will be required to remit or reimburse the original funds

extended by PCCP.

G. Competition Eligibility

• PCCP funded research projects for individuals are not eligible for competition in PCCP

conventions.

II. GUIDELINES FOR APPROVAL OF RESEARCH GRANTS INDIVIDUAL/INSTITUTION

A. Research protocols should be submitted to the PCCP Research Screening Committee through

PCCP secretariat.

B. Protocols must contain the endorsement of the Section Chief of the Accredited Training Institution

and the Training Officer or Research Coordinator. Protocols must be submitted for review toy the

Institutional Review Board (IRB) and Ethics Committee.

C. Approved research protocols by the PCCP Research Committee should be submitted to the PCCP

Board of Directors for approval.

D. A document from PCCP to be signed by the Principal Investigator and the Chair of the Research

Committee should outline the terms of the grant including target completion and progress report.

The individual/institution may apply for a maximum of 50,000 Php. The budgetary allocation

however may be increased to 300,000 Php for a study of national scope.

E. Fifty percent of the approved budget should be released upon approval.

F. A completed report of the research should be submitted to the research committee and a progress

report in the middle of the project (according to its timeline).

G. If the paper is mainly funded by PCCP then it reserves the right to publish the paper in its own

journal, unless it waives its rights.

H. A progress report must be submitted midway through the project, further tranches maybe released

based on the report. The first 50% of the fund will only be released upon submission of the letter of

approval for the protocol by the institution’s Ethics Review Board or Ethics Committee. The grant

recipients are then required to submit a progress and a financial report every 3 months thereafter.

The next 40% of the fund will be given when they submit a report of their findings after 6 months,

indicating in the Gantt chart what have been achieved, as well as a financial report of their

expenses. 10% of the fund will be given when they present the completed data and analysis with

financial report.

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Vol. 19 | Issue 03 | September 2018 46

J. Finished papers should be presented during the annual PCCP convention.

K. If the major source of the funding for the research project comes from PCCP research funds, then

PCCP unless it waives its rights, has the right to publish it in its own journal.

L. Any study that has received a grant from the PCCP must include the logo of the PCCP in oral or

spoken presentations. For publications, an acknowledgment is required.

M. A paper not finishing during the proscribed period of implementation must justify in writing or else

forfeit the remainder of the funding and required to remit or reimburse the original funds extended by

PCCP.

N. Research papers conducted in multiple sites are encouraged and allowed. However, for PCCP

funding purposes, a single coordinating institution and proponent will be principally responsible to

PCCP.

O. Completed report of research should be submitted to the PCCP according to the protocol timeline.

P. Finished papers should be presented during the PCCP annual convention but not included in the

research contest.

III. GUIDELINES FOR APPROVAL OF TRAVEL RESEARCH GRANTS FOR FELLOWS-IN-TRAINING

A. For pulmonary fellows-in-training, a yearly total allotment of 7,000 USD will be given for papers

accepted for international presentation (oral, poster) in amounts of 700 USD for oral presentations

and 500 USD for poster presentation each to be screened by the research committee and

approved by the PCCP board.

B. Criteria for inclusion are international conferences on pulmonary diseases and disorders and

excludes support for conferences conducted in the Philippines.

C. A maximum of three (3) grants per institution per year will be given.

D. Requirements: Application letter of fellow-in-training, endorsed by TO or head and acceptance

letter from the international scientific organization.

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Philipp J Chest Dis 201847

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OUTSIDE BACK COVER

The Philippine Journal of Chest Diseases

An official publication of:

Philippine College of Chest Physicians

84-A Malakas St., Pinyahan, Quezon City, Philippines

Email: [email protected]

Phone: (+632) 924 9204