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• PCCP Position Statement on E- Cigarettes
• MDMA-induced pneumothorax
Volume 19 Number 4
October-December 2018
PHILIPPINE COLLEGE OF
CHEST PHYSICIANS
RESEARCH AGENDA
2019-2023
PHILIPPINE COLLEGE OF CHEST PHYSICIANS OFFICERS 2018-2019
PHILIPPINE JOURNAL OF CHEST DISEASESAN OFFICIAL PUBLICATION OF THE
PHILIPPINE COLLEGE OF CHEST PHYSICIANS
Lenora C. Fernandez, MD, FPCCP
President
Malbar G. Ferrer, MD, FPCCP
Vice President
Ivan N. Villespin, MD, FPCCP
Secretary
Gregorio P. Ocampo, MD, FPCCP
Treasurer
Imelda M. Mateo, MD, FPCCP
Eileen G. Aniceto, MD, FPCCP
Ma. Janeth T. Samson, MD, FPCCP
Jubert P. Benedicto, MD, FPCCP
Virginia S. de los Reyes, MD, FPCCP
Board Members
Charles Y. Yu, MD, FPCCP
Immediate Past President
Editor-in-Chief
Evelyn Victoria E. Reside, MD, FPCCP
Managing Editor
Camilo C. Roa, Jr., MD, FPCCP
Copy Editor
Blesilda O. Adlaon
Editorial Assistant
Ivan Noel G. Olegario, MD, MDC
The opinions and data expressed in the Philippine Journal of Chest Diseases (PJCD) are those of the individual authors. They are not
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Address all communication and manuscripts for publication to the following: The Editor, Philippine Journal of Chest Diseases, 84-A Malakas
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The Philippine Journal of Chest Diseases
publishes scientific papers in the field of
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JOURNAL ARTICLE: Tanchuco JQ, Young J.
Normal standards for spirometric tests in Filipino
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INSTRUCTIONS TO AUTHORS
BOOK: Kelley MA, Fishman AP. Exercise
Testing. In: Pulmonary Diseases. 2 edition.
Fishman AP, (ed.). McGraw-Hill Book Co.; 1989.
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Editorial: The PCCP, the PJCD and the pulmonary researcher
Philippine College of Chest Physicians Research Agenda Setting
2019-2023
Appendix I: Review of local researches
Appendix II. Revised guidelines on research grant applications
OCTOBER-DECEMBER 2018 VOLUME 19 NUMBER 4
1
3
30
43
Philipp J Chest Dis 201811
EDITORIAL
The PCCP, the PJCD and the
pulmonary researcher
Evelyn Victoria E. Reside, MD, FPCCP
Editor-in-Chief
As the year comes to a close, it is but
fitting to end with a clear understanding of
what knowledge gaps there are and what
needs to be done to fill them, with regards to
the realm of pulmonary medicine in the
Philippines.
Indeed, with more than seven
thousand islands, and more than 100 million
people, in an environment akin to a cultural
hotpot from north to south, to generate
research in a small corner of the country, and
to claim its results as attributable to the
whole, will never be fair nor accurate for the
general population. Although there are data
from some small studies which hold
significant value, what is more evident is
that the country needs data generated on a
larger scale, which is perpetually a challenge
considering the architecture of the country,
and how most pulmonary specialists are
distributed, with practice primarily in
abundance in the urbanized areas. Moreover,
there is also the fact that pulmonary training
programs are not as common as other internal
medicine subspecialties, so that the number of
those who are compelled to conduct
pulmonary research become even less.
Nevertheless, there is hope for the
pulmonary researcher. This issue of the PJCD
highlights the current state of published local
knowledge contributing to the landscape of
useful medical information. However, as
pulmonary medicine is dynamic, so should
research be dynamic as well. The mind must
“If we knew what it was we were doing, it would not be called research, would it?”
- Albert Einstein
Vol. 19 | Issue 03 | September 2018 22Vol. 18 | Issue 02 | June 2017
always be curious for there is an overflow
of patient resources continuously avail-
able, and there is always a public health
concern associated with the lungs, such as
smoking and pulmonary infections. But this
issue simplifies matters for the prospective
researcher and curious pulmonologist; it
already identifies the gaps and the
questions, and all that needs to be done is to
answer them. Such is the necessity and the
urgency of national data: the PCCP has
already set the stage, it is now up to the
College to respond.
And to respond will not only be to
heed the call of the PCCP, but will also be
to respond to the needs of our fellow
Filipinos.
“Research is what I’m doing when I
don’t know what I’m doing.”
- Wernher von Braun
Philipp J Chest Dis 20183
PHILIPPINE COLLEGE OF CHEST PHYSICIANS
RESEARCH AGENDA 2019-2023
Leadership Group:
Dr. Virginia S. de los Reyes
Dr. Lenora Fernandez
Technical Working Group:
Dr. Luisito Idolor
Dr. Jubert Benedicto
Dr. Aileen David-Wang
Dr. Raiza Visita
Dr. Miriam Lalas
Participants
PCCP Board of Directors:
Dr. Lenora Fernandez
Dr. Ivan Villespin
Dr. Jubert Benedicto
Dr. Eileen Aniceto
Dr. Virginia de los Reyes
Technical Adviser:
Professor Cynthia Cordero
• MS Public Health, University of the Philippines
• Master of Medical Statistics, University of Newcastle, Australia
• Professor, Department of Clinical Epidemiology, UP College of Medicine
• Project Leader, PNHRS Initiative to Develop Guidelines for Health
Research Prioritization
• Member, Research Agenda Committee, Philippine National Health
Research System (1990-2017)
Research Agenda Setting Workshop, September 1, 2018
AVR Lung Center of the Philippines
Vol. 19 | Issue 03 | September 2018 4
Cluster on Chronic Airway Diseases:
Dr. Gene Louie Philip Ambrocio
Dr. Aileen David-Wang
Dr. Chona De Vera
Dr. Glynna Ong-Cabrera
Dr. Tim Trinidad
Dr. Eileen Aniceto
Cluster on Critical Care/Vascular/Sleep:
Dr. Ma. Paz Mateo
Dr. Christopher Cortes
Dr. Rodolfo Dizon Jr.
Dr. Geraldine Garcia
Dr. Patrick Gerard Moral
Dr. Russel Omena
Cluster on ILD/OLD/Lung malignancy/Smoking
Dr. Shane Ceniza-Boiser
Dr. Dina Diaz
Dr. Melissa Lim-Bagay
Dr. Ma. Encarnita Limpin
Dr. Kriselda Tan
Dr. R. Tipones
Cluster on Pulmonary Infections
Dr. William Del Poso
Dr. Jesus Egargo
Dr. Jose Herson Morfe
Dr. Rodolfo Pagcatipunan Jr.
Dr. Jubert Benedicto
Dr. Luisito Idolor
Philipp J Chest Dis 20185
Cluster on Education & Training
Dr. Guilvic Tirso Aspiras
Dr. Bernice Ong-Dela Cruz
Dr. Christine Agatha Untalan
Facilitators:
Professor Cynthia Cordero
Dr. Virginia de los Reyes
Vol. 19 | Issue 03 | September 2018
INTRODUCTION
The Philippine College of Chest Physicians (PCCP) in pursuing its mission and vision,
is committed to supporting relevant and quality research to improve our country’s
health. As the leading expert in pulmonary health, PCCP envisions itself to be the
catalyst for meaningful, systematic and relevant research on lung diseases. However,
given its limited resources and the inequity in global research funding, there is a need
to channel these limited resources to answer the most important research questions
with the greatest impact and relevance.
On July 2, 2017, during the PCCP strategic planning workshop, it was decided to
reinforce the research capability of the College through the following action plans: 1.)
To revisit the PCCP research priorities and align with Department of Health (DOH)
priorities , 2.) To increase PCCP identified research involving the different Councils,
Chapters, training institutions in collaborative research, and 3.) To create a network of
funding agencies for the identified priority research topics.
To revisit the PCCP research priorities, the PCCP spearheaded and supported a
research agenda setting initiative. Through this activity which culminated with a
workshop on September 1, 2018., it was hoped that PCCP could better prioritize and
integrate the College’s research activities. PCCP emphasized inclusiveness by
engaging the PCCP’s Councils, Chapters and training institutions in crafting a
research agenda. PCCP recognized national frameworks particularly the Philippine
National Health Research Agenda to guide the agenda setting initiative.
Process and criteria for research priority setting
There were 3 essential phases in research priority setting, namely pre-
implementation/preparatory, implementation and post-implementation phases.
For the pre-implementation phase, we first identified the three essential groups of
people involved and their functions. These are: 1) Leadership- ensures the funding
and other needed resources, and identifies a technical group. 2) Technical Working
Group – functions as the research, organizational and documentation team 3) Agenda
Setting Participants - research stakeholders who would actively participate in the
process.
6
Philipp J Chest Dis 20187
Preparatory Phase
On July 26, 2018, the three essential groups and its members were identified. The
leadership group included the current PCCP President Dr. Lenora Fernandez, Board
Member Dr. Virginia de los Reyes, and the current chairman of the research
committee. The technical working group (TWG) was composed of Dr. Luisito Idolor, Dr.
Jubert Benedicto, Dr. Aileen Wang, Dr. Raiza Visita, and Dr. Miriam Lalas). The group
decided to consult Professor Cynthia Cordero from the Department of Clinical
Epidemiology University of the Philippines College of Medicine to guide them on the
agenda setting process. The leadership and technical working group decided to invite
research stakeholders namely Chairs of the PCCP councils, Chairs of the local
chapters, research representatives of training institutions and Consultant advisers of
PCCP.
A vital part of the preparatory phase is contextualization which includes specifying an
over-arching framework. Contextualization included the scope and focus of the
research agenda setting for PCCP, identifying the end-users, the guiding values and
principles to be used and followed, and identifying the capacity of the College and
available resources. It also included the planning for its implementation and
dissemination of the output among the college members. It was important for the
group to gather information or data that were associated with the objectives of the
college and current health needs in the field of respiratory medicine, and to ensure
inclusiveness from different stakeholders and end-users’ concerns and encourage
active participation. Guiding principles such as equity, cost-effectiveness and preferred
type of research were specified at this phase. Also at this phase political and economic
factors that may influence our agenda were identified and how these are aligned with
the national health agenda.
Finally, a context map (see figure 1) was drawn to tie all components by an
overarching framework that explains the rationale behind our health research
prioritization activity and shows how health research prioritization should lead to
improved lung health status of the population.
In this context map (Figure 1), it was decided that the main focus of research will be
chronic airway diseases, infectious diseases, lung malignancy, critical care/vascular,
as well as education and training. These research areas also reflect how the PCCP is
currently organized with its different specialty councils. Outside the box in this
diagram, will be the National Health Research Agenda (NUHRA) that will help guide
our research prioritization; and the Department of Health (DOH), and World Health
Vol. 19 | Issue 03 | September 2018 8
Organization (WHO), whose policies may influence the agenda and may be our
partners in providing funding and other resources. The goal of this health research
prioritization is to generate researches that will improve health status of Filipinos by
decreasing morbidity and mortality due to lung diseases.
Information Gathering
Before the implementation phase, information that are relevant to health research
(previous agenda, morbidity mortality causes, national health agenda, prevalence and
cost-effectiveness studies) have to be gathered, processed and integrated. It was the
task of the technical working group to gather these relevant information that may be
considered a reference/baseline for the agenda setting participants or situational
analysis for the prioritization exercise.
A previous PCCP research agenda setting workshop in 2006 identified 11 topics of
high research importance. The following are: 1. Tuberculosis, 2. Epidemiologic studies,
3. Chronic obstructive pulmonary disease, 4. Adherence to Clinical Practice Guide-
Figure 1. Contextual Framework
Philipp J Chest Dis 20189
lines, 5. Lung Cancer treatment outcomes, 6. Mechanical Ventilation, 7. KAP studies,
8. Economic burden of pulmonary diseases, 9. Smoking, 10. Environmental/
occupational studies, and 11. Complementary and alternative medicine. There is
however a clear need to update these priority research areas and to improve the
uptake of the research agenda in terms of actual studies conducted based on this
agenda.
The Philippine National Health Research Agenda has 6 themes comprising the
research priorities, namely: responsive health system, research to enhance and
extend healthy lives (ex. communicable and non-communicable disease), holistic
approaches to health and wellness, health resiliency (ex. occupational &
environmental health), global competitiveness and innovation in health (ex diagnostics;
mapping of health risks & resources), and research in equity and health. The outputs
of these priority areas may be used in the development of personalized medicines,
diagnostics and therapeutics, and in support to the health & clinical practice guidelines
and policies in its identified priority respiratory diseases or conditions, such as
Pneumonia, Tuberculosis, Multidrug-resistant Tuberculosis and Lung Cancer. The
NUHRA is useful in providing a national framework for research areas that PCCP may
venture into. However, its scope may be too broad and there is a need to formulate
more specific research areas that PCCP currently needs.
Burden of pulmonary diseases and local researches
Pulmonary diseases such as PTB, COPD, pneumonia, and lung cancer remain in the
top 10 causes of morbidity and mortality in the country.
According to DOH data in 2013 (Fig.2), the top 10 causes of mortalities included
Pneumonia, lower respiratory tract infection and Tuberculosis of all forms at the 4th, 7th
and 8th places. The tope 10 causes of morbidity (Fig.3) included acute respiratory
infection, Acute Lower respiratory tract infection or Pneumonia, Bronchitis and PTB at
the 1st, 2nd, 5th and 8th place.
More recently, the Institute for Health Metrics and Evaluation (IHME), an independent
global health research center at the University of Washington published the Global
Burden of Diseases 2016 document in LANCET in 2017. This provides a
comprehensive assessment of cause-specific mortality for 264 causes in 195 locations
from 1980 to 2016 with >80,000 different data sources. The top ten diseases causing
mortality among Filipinos in 2016 where identified and three respiratory illnesses such
as Lower respiratory tract infection, Tuberculosis, and COPD ranked 3rd, 5th and 7th
Vol. 19 | Issue 03 | September 2018
place respectively. While the top respiratory disease causes of morbidity among
Filipinos according to this document were respiratory tract infection and tuberculosis at
2nd and 8th spot. They also identified tobacco use and air pollution as among the top
10 risk factors for mortality and disability among Filipinos (Fig. 4, 5).
In terms of published local researches on lung diseases, it was noted that these were
mostly small observational studies usually initiated by residents and fellows as a
prerequisite for completion of training. The TWG was able to review 105 articles from
three journal archives (PCP Journal, PCCP Journal and Acta Medica) for the past five
years (2013-2018). Among the research topics, majority were on chronic airway
diseases (34%), critical care, vascular and sleep medicine topics at 28%, Infectious
lung disease 25%, ILD/smoking/lung cancer 11% and others 2% (Fig. 6). Majority of
these studies though analytical (56.2%) in design, were mostly observational studies
(93.2%) and only 0.7% were interventional studies (Fig.7). It was important also to
note that the sample size in the majority of these studies were small and mostly done
at a single-center setting. Nonetheless, this list of local studies (Appendix 1) is helpful
in terms of giving us an idea of what has already been done as reference and baseline
for the agenda setting.
10
Fig. 2. Leading Causes of Mortality, DOH 2013
Philipp J Chest Dis 201811
Fig. 3. Leading Causes of Morbidity, DOH 2014
Fig. 4. Leading Causes of Death & Disability. Global Burden of Diseases 2016
Vol. 19 | Issue 03 | September 2018 12
Chronic Airway Disease; 34%
Crit Care/Vascular/Sleep; 28%
ILD/Malignancy/Smoking/Air Pollution; 11%
Infectious lung diseases; 25%
Others; 2%
Fig. 6. Distribution of Researches by topic.
The mortality, morbidity, and local research reviews supported our conceptual
framework in emphasizing our identified priority research areas. The information
gathered from the preparatory phase also served as the spring board to generate the
initial list of topics.
40
6
Observational; 55
Interventional; 4
0
10
20
30
40
50
60
70
Descriptive Meta-analysis Analytical
Fig. 7. Classification of Local Researches on lung diseases by Study Design
Philipp J Chest Dis 201813
Implementation Phase
The different PCCP councils and chapters submitted a list of priority research topics to
be included in the research agenda based on their recently completed research
projects, ongoing researches and planned research projects. On August 13, 2018, an
initial list of research topics was generated by the technical working group based on the
gathered information during the preparatory phase and the contribution of the PCCP
councils and chapters.
On August 16, 2018, the Leadership and the TWG drew a criteria for ranking the initial
list of research topics. The criteria included: magnitude of the problem (based on
prevalence, urgency, burden to population); likelihood that results of research can
influence practice (ex. health policy, clinical practice guidelines); likelihood that results
of research can potentially decrease disease burden; feasibility of the research based
on existing resources of PCCP; and if the research can be ethically conducted (Table
1). The assigned weight per criteria (multiplier) was also decided on, with the criterion
of magnitude of the problem being assigned the highest weight (Table 2).
On September 1, 2018, the research agenda setting workshop was held at the Lung
Center of the Philippines. This was attended by representatives of the various councils,
chapters, and PCCP training institutions, technical working group, and the PCCP
leadership. Professor Cynthia Cordero and Dr. Virginia de los Reyes served as the
facilitators for this workshop.
There were a total of 27 research topics that were generated from the input of the
different councils, chapters, training institutions and the technical working group (See
Table 3).
The participants were asked to score and rank the various topics based on the criteria
presented by the TWG. The participants were also divided into clusters as follows
based on the concept map: obstructive airway disease, critical care/vascular/sleep,
interstitial lung disease/malignancy/smoking/air pollution, infectious lung disease and
Table 1: Criteria for Ranking
1. Magnitude of the problem (based on prevalence, urgency, burden to population)
2. Likelihood that results of research can influence practice (ex. Health policy, clinical
practice guidelines)
3. Likelihood that results of research can potentially decrease disease burden
4. Is the research feasible based on existing resources of PCCP?
5. Can the research be ethically conducted?
Vol. 19 | Issue 03 | September 2018 14
Table 2: Scoring Worksheet
Criteria Magnitude
of the
problem
Likelihood
that
results of
the
research
can
influence
practice
Likelihood
that the
results of
the
research
can
potentially
decrease
disease
burden
Is the
research
feasible
based on
existing
resources
of PCCP?
Can the
research
be
ethically
conducted
?
Score
Assigned
weight per
criteria
(multiplier)
2 1 1 1 1
Proposed
research
topic
SCORE TOPICS PER CRITERIA (from 1-10); 10 as the highest score
education/training. Aside from scoring and ranking the general research topics, the
groups were tasked to formulate clinical questions using the PIOM format as well as
generate related new topics. The research questions were not meant to restrict the
agenda’s field of study, but rather to assist potential researchers in formulating their own
research questions.
After the presentation of each group, the over-all ranking of topics as scored by the
participants were presented. The final topics were agreed upon during the open forum
wherein ranking and consensus were used in reaching decisions on prioritization.
Philipp J Chest Dis 201815
Obstructive airway disease
1. The burden of obstructive lung disease II study
2. Study of national asthma prevalence
3. Non-adherence to pharmacologic treatment in the Clinical Profile and Survival
Study of Filipino COPD patients (CPASS) cohort
4. Non-adherence to non-pharmacologic treatment in the CPASS cohort
5. Real-world experience/studies of asthma management of both MDs and
non-MDs
Critical Care/Vascular/Sleep
1. Prevalence of pulmonary embolism among critically-ill patients
2. Physician knowledge and attitude on OSA
3. ARDS registry
4. Community-based prevalence of OSA in the Philippines
5. Patient adherence to PAP therapy
6. Local version of Epworth Sleepiness Scale
ILD/Malignancy/Smoking/Air Pollution
1. Development of evidence-based recommendations on the use of e-cigarette
2. Clinical profile of pulmonary malignancies among Filipinos
3. Clinical profile of e-cigarette users in Metro Manila
4. KAP of pulmonologists on occupational lung disease
5. Survey of most common occupational lung diseases in the Philippines
6. Exposure to air pollution of workers who commute daily in Metro Manila
7. Accuracy of PET scan in differentiating TB vs malignancy
Infectious lung disease
1. Evaluation of treatment practices among pulmonologists for TB retreatment cases
2. Local guidelines for TB pre-employment
3. Surveillance of commonly isolated respiratory pathogens
4. Practices among pulmonologists regarding vaccination
5. Isoniazid prophylaxis treatment among healthcare workers with latent TB infection
6. Profile of bronchiectasis patients in the Philippines
Education/Training
1. Healthcare utilization of different pulmonary diseases
2. Assessing relevance of required pulmonary procedures and degree of
preparedness of PCCP graduates in their performance
3. Formulation of outcome-based curriculum for PCCP pulmonary fellowship
program
Table 3. List of Research Topics
Vol. 19 | Issue 03 | September 2018 16
CRITICAL CARE/VASCULAR/SLEEP MEDICINE
CLUSTER RANKING
Critical Care/Vascular/SleepAverage
scoreRank
Prevalence of pulmonary embolism among critically-ill
patients47.13 1
Physician knowledge and attitude on OSA 46.50 2
ARDS registry 46.17 3
Community-based prevalence of OSA in the Philippines 45.29 4
Patient adherence to PAP therapy 43.88 5
Local version of Epworth Sleepiness Scale 43.67 6
Research topic 1: What are the risk factors for CTPA diagnosed PE?
Identified initiator: PCCP Council on Critical Care, Training institutions
Timeline: 4-5 years
P-CTPA diagnosed Pulmonary embolism
O-Clinical Characteristics
M-Observational, survey questionnaire
Research topic 2: Among pulmonologists, what is the state of awareness and
practice on OSA?
Identified initiator: PCCP Council on Sleep, Training institutions
Timeline: 2 years
P-practicing pulmonologist members of the PCCP
O-Knowledge, attitude and practices
M-Observational, survey questionnaire
Research topic 3: What is the clinical profile of ARDS patients admitted in the
ICU of PCCP accredited hospitals?
Identified initiator: PCCP Council on Critical Care, Training institutions
Timeline: 4-5 years
P-ICU patients diagnosed with ARDS
O-Clinical Characteristics of ARDS patients admitted at the ICU
M-Observational, survey questionnaire
Philipp J Chest Dis 201817
Research topic 4: Among hypertensive patients what is the prevalence of those
at risk for OSA?
Identified initiator: PCCP Council on Sleep Medicine, Training institution
Timeline: 3 years
P-Hypertensive patients
O-Prevalence of OSA risk factors
M-Observational, use of STOP-BANG questionnaire
Research topic 5: Among PSG-diagnosed OSA patients, what is the adherence to
PAP therapy?
Identified initiator: PCCP Council on Sleep
Timeline: 3-5 years
P-PSG diagnosed OSA patients
O-adherence data through self-report and machine compliance use data
M-Descriptive, Questionnaire, compliance data
OBSTRUCTIVE AIRWAY DISEASE
CLUSTER RANKING
Obstructive airway diseaseAverage
scoreRank
The burden of obstructive lung disease II study 50.54 1
Study of national asthma prevalence 50.29 2
Non-adherence to pharmacologic treatment in the CPASS
cohort49.33 3
Non-adherence to non-pharmacologic treatment in the CPASS
cohort47.46 4
Real-world experience/studies of asthma management of both
MDs and non-MDs46.33 5
Research topic 1: What is the prevalence, burden and risk factors for COPD in
urban and rural settings in the Philippines? Burden of Chronic Obstructive
Pulmonary Disease (BOLDer)
Identified initiator: PCCP COPD Council, Chapters, Training Institutions
Timeline: 3 years
Vol. 19 | Issue 03 | September 2018 18
P: all adults > 40 years of age residing in selected rural communities and urban cities
nationwide; multi-stage random sampling procedure
• By region, by province, by municipality
• Metro-cities (NCR, Metro Cebu, Metro Davao)
O: prevalence, burden and risk factors(smoking, other environmental/occupational risk
factors)
M: Cross sectional analytic; Cross Sectional survey using CORE questionnaire,
Spirometry
Research topic 2: Non-adherence to pharmacologic treatment in the Clinical Profile
and Survival Study of Filipino COPD patients (CPASS) cohort
2.1. Among physicians managing the CPASS COPD cohort, is there a difference in the
adherence to the GOLD 2017 recommendations?
Identified initiator: PCCP COPD Council, Chapters, Training Institutions
Timeline: 3 years
Significance: Strategize educational intervention for physicians
P: FPCCP vs non-FPCCP pulmo trained doctors, internists, general practitioners
O: adherence to the GOLD 2017 recommendations
M: Observational Retrospective (or Prospective) Cohort Study; survey
2.2. Among the CPASS cohort, what are the factors predictive of or are associated with
patients’ non-adherence to pharmacologic treatment?
Initiator: PCCP / COPD Council
Significance: Strategize educational intervention for patients
P: CPASS subjects who are non-adherent to pharmacologic management
O: Prevalence of non-adherence due to: Economic reasons, Complex drug regimens,
Drug is ineffective, Too many drugs, Side effects, Difficult to use, Inadequate instructions
from physician
M: Descriptive Study; questionnaire
2.3. Among the CPASS cohort, is management adherent to the GOLD 2017 guidelines
associated with or predictive of better outcomes compared to non-adherent
management?
Initiator: PCCP / COPD Council
Significance: Formulation of CPG guidelines
Philipp J Chest Dis 201819
P: CPASS subjects
O: exacerbation rates, symptom control, QOL, health care utilization
M: Observational Retrospective (or Prospective) Cohort Study; use of questionnaires,
CAT, SGRQ
Research topic 3: Non-adherence to non-pharmacologic treatment in the CPASS
cohort
3.1. What is the QOL of COPD patients undergoing pulmonary rehabilitation compared
with those not on pulmonary rehabilitation?
Initiator: PCCP / COPD Council
P: CPASS patients
I: Pulmonary Rehabilitation (6 weeks and above)
O: Quality of life (CAT Score and Six Minute Walk Distance; Borg, Dyspnea Scale
M: cross-sectional multi-center survey
3.2. Frequency of exacerbation among COPD patients undergoing PR as compared to
those not on PR
3.3. Survival Rate of COPD patients undergoing PR compared to those not on PR
Research topic 4. Study of National Asthma Prevalence
Initiator: PCCP /Asthma Council / PCCP Chapters
4.1 Among clinically diagnosed asthma patients, what is the level of asthma control?
P: adult asthmatic patients (physician-diagnosed, current asthma symptoms or taking
asthma medications); rural and urban, community and hospital-based
O: Asthma control (GINA criteria for asthma control)
M: Cross-sectional descriptive survey; use of ACT, Questionnaire (socio-demographic
data, respiratory symptoms, risk factors), spirometry with bronchodilator testing
4.2 Among patients diagnosed with asthma by spirometry and GINA definition, what is
the national prevalence, current severity, and GINA-defined level of control?
P: Asthma patients diagnosed by spirometry
O: national prevalence, current severity, and GINA-defined level of control
M: cross-sectional descriptive study, questionnaire, spirometry
Vol. 19 | Issue 03 | September 2018 20
4.3 Among patients with asthma, what are the prevalence of step 4-5 GINA/ERS-
defined severe asthma and determinants of severity?
4.4 Among adult Filipinos with asthma, is their current management adherent to
current national and GINA recommendations?
(Can be combined with previous surveys)
P: adult Filipinos with asthma managed by GP, IM, specialist, or self-managed
O: adherence to national and GINA recommendations
M: cross-sectional descriptive study, questionnaire
Research topic 5. Real-world experience (RWE) studies of asthma
Initiator: Asthma Council, PCCP Chapters, training institutions
5.1 Among physicians taking care of adult asthmatics in their outpatient clinics,
what are their knowledge, attitude and current practices in the diagnosis and
management of asthma?
P: Specialists, IMs, GPs
O: KAP measures
M: cross-sectional descriptive study, use of questionnaires to measure knowledge and
attitude. To measure practice: Asthma Council to formulate typical asthma cases (GINA
Steps 1-5) and develop questions on diagnosis and management
5.2 Among adult patients with asthma, what are the factors that independently
predict or are associated with increased exacerbations and poor outcome?
P: GINA-defined controlled vs uncontrolled asthma (visited the emergency room at least
2x in the past year)
O: exacerbations
M: Case-control, cross-sectional survey or prospective cohort
5.3 Among adult patients consulting at outpatient clinics, what are the
comparative rates in the prescription of oral medications versus inhalers in their
maintenance management?
P: asthma patients at OPD
O: rates in the prescription of oral medications versus inhalers in the maintenance
management of asthma; specialists vs internists vs general practitioner
M: Cross Sectional Survey; can be social media sourced
Philipp J Chest Dis 201821
5.4 Among adult patients consulting at outpatient clinics, are asthma outcomes
better among patients given ICS/LABA for at least 6 months by MDI vs dry powder
inhaler?
P: adult asthmatic patients consulting at outpatient clinics
I: ICS/LABA for at least 6 months by MDI vs dry powder inhaler
O: exacerbation rates, GINA control status, health care utilization, ACT, asthma QOL
M: Pragmatic RCT or prospective cohort study
5.5 Among adult patients consulting at outpatient clinics, what are the errors in
inhalational technique (pMDI vs DPI)?
P: adult asthmatic patients consulting at outpatient clinics using pMDI or DPI
O: errors in inhalational technique
M: Observational study
5.6 Among adult patients consulting at outpatient clinics, will an inhaler
technique instruction program provide better asthma outcomes compared to
standard practice?
(Can be combined with previous study)
P: adult asthmatic patients consulting at outpatient clinics
I: inhaler technique instruction program
O: exacerbation rates, GINA control status, health care utilization, ACT, asthma QOL
M: Pragmatic RCT or Prospective Cohort study
Research topic 6. Healthcare utilization for asthma exacerbations
PCCP / Asthma council initiated; Philhealth
Among adult asthmatic patients admitted for acute exacerbation included in the Phil
Health database:
1. What are the direct and indirect costs of healthcare utilization? Method: Health
economics measurement
2. What are the risk factors associated with hospital admission? Method: case control /
cross sectional
3. What are the characteristics and outcomes associated with more severe asthma
exacerbation? Method: case control
Vol. 19 | Issue 03 | September 2018 22
INFECTIOUS LUNG DISEASE
CLUSTER RANKING
Infectious lung disease
Average
score Rank
Evaluation of treatment practices among pulmonologists for
TB retreatment cases 53.04 1
Local guidelines for TB pre-employment 52.79 2
Surveillance of commonly isolated respiratory pathogens 48.67 3
Practices among pulmonologists regarding vaccination 48.33 4
Isoniazid prophylaxis treatment among healthcare workers
with latent TB infection 47.96 5
Profile of bronchiectasis patients in the Philippines 47.83 6
Research topic 1: Evaluation of treatment practices among pulmonologists for
TB retreatment cases
Multi-center; Council or chapter initiated
1.1 Comparison of Programmatic (DOTS) vs non programmatic (clinic) treatment
for retreatment cases
P: TB retreatment cases
I: Programmatic (DOTS) vs non programmatic (clinic) treatment
O: cure rate, completion rate, treatment failure, relapse
M: cross-sectional cohort
1.2 Knowledge Attitude Practices of physicians regarding TB retreatment cases
Research topic 2: Local guidelines for TB pre-employment
PCCP, Council initiated
• Knowledge Attitude Practices of physicians regarding TB pre-employment
• Adherence to current TB pre-employment guidelines
• Development of updated guidelines
Research topic 3: Surveillance of commonly isolated respiratory pathogens
Private hospitals/PCCP training institutions
P: hospitalized patients with community acquired pneumonia
O: isolated respiratory pathogens, drug sensitivity
M: observational study; standardized collection of respiratory specimen
Philipp J Chest Dis 201823
Research topic 4: Practices among pulmonologists regarding vaccination
P: patients seen at health facilities
O: vaccination rate; type of vaccinations given; facilitating and hindering factors
M: observational study; patient survey
Research topic 5: Isoniazid prophylaxis treatment among healthcare workers
with latent TB infection
TB Council, PCHRD
P: healthcare workers with latent TB infection
I: Isoniazid prophylaxis treatment
O: prevention of active PTB over 3-5 years
M: RCT
Research topic 6: Risk factors for poor treatment outcomes of drug sensitive TB
PCCP/Training Institutions/Chapters; National TB Program funding
P: Patients with drug sensitive tuberculosis under DOTS setting on Category 1
treatment
O: cure, treatment completed, lost to follow up, treatment failure, relapse, adverse
events
M: case control study
Research topic 7: Profile of bronchiectasis patients in the Philippines (ANOLD
Bronchiectasis study)
What are the characteristics of patients with bronchiectasis in the Philippines?
PCCP council initiated; Sponsored by South Korean Study Group
Timeline: 3 years
P: Filipino patients with non-cystic fibrosis bronchiectasis
O: etiology; clinical characteristics (phenotype, etiology:, exacerbation, hospitalization,
mortality), disease burden
M: cross sectional study; use of questionnaires, imaging, PFT, bacteriologic studies
Vol. 19 | Issue 03 | September 2018 24
LUNG MALIGNANCY/ILD/OLD/SMOKING/AIR POLLUTION
CLUSTER RANKING
ILD/Malignancy/Smoking/Air Pollution
Average
score Rank
Development of evidence-based recommendations on the use of
e-cigarette 49.58 1
Clinical profile of pulmonary malignancies among Filipinos 48.71 2
Clinical profile of e-cigarette users in Metro Manila 47.83 3
KAP of pulmonologists on occupational lung disease 47.33 4
Survey of most common occupational lung diseases in the
Philippines 46.75 5
Exposure to air pollution of workers who commute daily in Metro
Manila 45.79 6
Accuracy of PET scan in differentiating TB vs malignancy 42.63 7
Research topic 1: Exposure to air pollution of workers who commute daily in
Metro Manila
PCCP Council initiated
Among jeepney commuters along major thoroughfares in Metro Manila, does the level
of total particulate matter exposure correlate with their lung function?
P- Jeepney commuters along major thoroughfares in Metro Manila
O-Lung Function
M-cross-sectional study, case control; total particulate matter exposure monitoring;
spirometry; respiratory symptoms
Research topic 2: What are the Knowledge, Attitude and Practices of
Pulmonologists in the Philippines towards Occupational Lung Disease?
P: Pulmonologists in the Philippines
O: KAP
M: Descriptive, questionnaire
Research topic 3: What is the prevalence of Occupational Lung Disease in the
Philippines?
P: Major Cities in the Philippines; representative industries
O: Prevalence of common occupational lung diseases, risk factors
M: Descriptive, questionnaire, interviews, spirometry
Philipp J Chest Dis 201825
Research Topic 4. Development of evidence-based recommendations on the use
of e-cigarette
4.1. What is the clinical profile of e-cigarette users in Metro Manila?
P: E-cigarette users in Metro Manila
O: Clinical profile
M: Descriptive; use of questionnaires
4.2. What is the relationship between E-cigarette use and smoking cessation?
P: conventional cigarette smokers vs dual (conventional and E-cigarette) smokers in
urban cities
I: E-cigarette
O: quit attempt rates, smoking cessation rates
M: prospective cohort study
Research Topic 5: What is the clinical profile of patients with pulmonary
malignancies based on an analysis of the Tumor Registry?
P: Patients with pulmonary malignancy registered with the Tumor Registry
O: Clinical profile, incidence of pulmonary malignancy among smokers vs non-
smokers, second hand smokers
M: Descriptive; use of questionnaire, data base
Research Topic 6: Accuracy of PET scan in differentiating TB vs malignancy
What is the reliability of the PET-CT in the setting of high TB burden in terms of
staging of lung malignancy?
P: Patients with lung malignancy with PET-CT
O: Sensitivity and specificity of PET-CT for staging of lung malignancy
M: cross sectional study
Vol. 19 | Issue 03 | September 2018 26
CLUSTER RANKING
Education/Training
Average
score Rank
Healthcare utilization of different pulmonary diseases 48.75 1
Assessing relevance of required pulmonary procedures and
degree of preparedness of PCCP graduates in their performance 48.71 2
Formulation of outcome-based curriculum for PCCP pulmonary
fellowship program 48.54 3
EDUCATION/TRAINING
Research Topic 1: Assessing relevance of required pulmonary procedures and
degree of preparedness of PCCP graduates in their performance
Initiator: PCCP, Training Institutions, Chapters
Timeline: 1 to 2 years
What is the relevance of the required pulmonary procedures and degree of
confidence in performing them in clinical practice among PCCP- accredited
pulmonologists?
P-All graduates of PCCP accredited pulmonary fellowship training program
O-Relevance of required procedure and confidence in the performance of the
procedure
M-Observational study via survey/ questionnaires (thoracentesis, bronchoscopy,
pleurodesis and pleural biopsy)
Research Topic 2: Health care utilization of different pulmonary diseases
Initiator: PCCP through different institutions / chapters
Timeline: 2-3 years
What is the cost of healthcare utilization among admitted patients with
pulmonary diseases (COPD, Asthma, Pneumonia, Lung CA, and PTB) in the
Philippines?
P- patients admitted for pulmonary diseases
O- cost of healthcare utilization
M- cross-sectional study; review of Philhealth data base
Philipp J Chest Dis 20181927
OVER ALL RANKING Average score
1. Evaluation of treatment practices among pulmonologists for TB
retreatment cases53.04
2. Local guidelines for TB pre-employment 52.79
3. The burden of obstructive lung disease II study 50.54
4. Study of national asthma prevalence 50.29
5. Development of evidence-based recommendations on the use of e-
cigarette49.58
6. Non-adherence to pharmacologic treatment in the CPASS cohort 49.33
7. Healthcare utilization of different pulmonary diseases 48.75
8. Clinical profile of pulmonary malignancies among Filipinos 48.71
9. Assessing relevance of required pulmonary procedures and degree
of preparedness of PCCP graduates in their performance48.71
10. Surveillance of commonly isolated respiratory pathogens 48.67
11. Formulation of outcome-based curriculum for PCCP pulmonary
fellowship program48.54
12. Practices among pulmonologists regarding vaccination 48.33
13. Isoniazid prophylaxis treatment among healthcare workers with
latent TB infection47.96
14. Clinical profile of e-cigarette users in Metro Manila 47.83
15. Profile of bronchiectasis patients in the Philippines 47.83
16. Non-adherence to non-pharmacologic treatment in the CPAS cohort 47.46
17. KAP of pulmonologists on occupational lung disease 47.33
18. Prevalence of pulmonary embolism among critically-ill patients 47.13
19. Survey of most common occupational lung diseases in the
Philippines46.75
20. Physician knowledge and attitude on OSA 46.5
21. Real-world experience/studies of asthma management of both MDs
and non-MDs46.33
22. ARDS registry 46.17
23. Exposure to air pollution of workers who commute daily in Metro
Manila45.79
24. Community-based prevalence of OSA in the Philippines 45.29
25. Patient adherence to PAP therapy 43.88
26. Local version of Epworth Sleepiness Scale 43.67
27. Accuracy of PET scan in differentiating TB vs malignancy 42.63
Vol. 19 | Issue 03 | September 2018 28
Post-implementation Phase
The last phase is the post-implementation phase wherein the process and results of
the research agenda setting workshop will be reported. The manuscript of the
workshop proceedings will be disseminated to the membership. Monitoring and
evaluation of the uptake of the research topics in the agenda will be carried out by
PCCP’s Research Committee.
PCCP has adopted measures to strengthen its research capabilities through the
formation a Research Committee with a fixed two year term. Among the
responsibilities of the Research Committee will be to carry out dissemination,
implementation and monitoring and evaluation of the PCCP Research agenda.
Additionally, it will oversee the approval of research grant proposals and funding. The
Research committee had reviewed and revised the policies, rules and regulations
regarding research grant applications with the objective of increasing the support of
PCCP for relevant research by its members. (Appendix 2: Revised guidelines on
research grant applications). The PCCP Research Committee will also link up with
partners in the government and private sectors who will be providing additional
funding and other resources.
This research agenda would hopefully set the direction for the research activities of
the College for the next five years. However, a fair and transparent appeal system
will be put in place. This process is essential to allow important topics that might
have been overlooked to be included and ensure that the agenda remains dynamic
and relevant.
A timeline of the research agenda setting process is outlined below (Table 3).
For queries on conduct, funding, or appeals process, please contact PCCP Research
Committee thru philchest.org, [email protected].
Philipp J Chest Dis 201829
Table 3. Timeline of Research Agenda Setting Process
Tasks Jul 30-Aug 5 Aug 6-12 Aug 13-19 Aug 20-26 Aug 27-30 Sep-01 Oct- Jan Feb Mar 2018 2023
Defining the context;
concept map
July 26-prep.
mtg
Planning for M&E
Information gathering
Follow up
attendees–follow up of
research topics
Generate initial list of
topics
Choosing & applying
criteria for ranking
Deciding on research
priorities
Aug 13- mtg of
TWG
Aug 16-mtg.
TWG
Reporting prioritization
process & results
Sep 1-RA
Workshop
Write up of report
Meet with Research Board
Disseminating the research
agenda
Write-up &
Publish the
document
Meet with
funding agencies
Distribute
manuscripts
during
Monitoring & Evaluation Every 6 months
Mar 2019
Vol. 19 | Issue 03 | September 2018 30
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rteria
l D
isease a
mong
Fili
pin
o C
hro
nic
Obstr
uctive P
ulm
onary
Dis
ease P
atie
nts
at
the O
utp
atie
nt
Depart
ment of
the L
ung C
ente
r of
the
Phili
ppin
es (
PJC
D v
ol 17 #
4)
10.B
acte
ria
l P
ath
ogens o
f P
atie
nts
with C
hro
nic
Obstr
uctive
Pulm
onary
Dis
ease (
CO
PD
) A
dm
itte
d for
Acute
Exacerb
atio
n a
t th
e L
ung C
ente
r of
the P
hili
ppin
es in
2011
–
2014 (
PJC
D v
ol 17 #
4)
Appendix I. Review of Local Researches
Philipp J Chest Dis 201831
N
98
,81
3
60
PO
PU
LA
TIO
N
Ad
ult a
dm
itte
d p
atie
nts
du
e to
Pn
eu
mo
nia
or
Bro
nch
iecta
sis
in IE
22
stu
die
s in
clu
de
C
OP
D
pa
tie
nts
an
d n
ote
d m
ort
alit
y
with
or
with
ou
r B
eta
blo
cke
rs
2 s
tud
ies
3 R
CT
s 4
,62
5 p
atie
nts
mo
d-
se
ve
re C
OP
D
SP
EC
IFIC
RC
T
Me
ta-a
na
lysis
Me
ta-a
na
lysis
Me
ta-a
na
lysis
Me
ta-a
na
lysis
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
ST
UD
Y
DE
SIG
N
Inte
rve
ntio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
TIT
LE
(R
efe
ren
ce
)
11
.Eff
ective
ne
ss o
f M
ech
an
ica
l C
ou
gh
Assis
t
(In
su
ffla
tor-
Exsu
ffla
tor)
am
on
g H
osp
ita
lize
d P
atie
nts
:
An
Op
en
-La
be
l R
an
do
miz
ed
Con
tro
l S
tud
y o
f
Me
ch
an
ica
l C
ou
gh
Assis
t (I
nsu
ffla
tor-
Exsu
ffla
tor)
am
on
g H
osp
ita
lize
d P
atie
nts
: A
n O
pe
n-L
ab
el
Ran
do
miz
ed
Con
tro
l S
tud
y (
PJC
D v
ol 1
8 #
1)
12
.Sa
fety
an
d b
en
efits
of b
eta
-blo
cke
rs in
ch
ron
ic
ob
str
uctive
pu
lmo
na
ry d
ise
ase
: a
re
vie
w o
f cu
rre
nt
evid
en
ce
an
d m
eta
-an
aly
sis
(P
JC
D v
ol 1
9 #
1)
13
.Me
ta-a
na
lysis
on
th
e u
se
of
Sta
tin
s in
Chro
nic
Ob
str
uctive
Pu
lmo
na
ry D
ise
ase
pa
tie
nts
(P
JC
D v
ol
17
#3
)
14
.Co
mp
ari
so
n o
f G
lyco
pyrr
on
ium
plu
s In
da
ca
tero
l
co
mp
are
d to
In
ha
led
Cort
ico
ste
roid
s p
lus L
on
g-A
ctin
g
Be
ta-A
go
nis
ts in
Pa
tie
nts
with
Ch
ron
ic O
bstr
uctive
Pu
lmo
na
ry D
ise
ase
: A
Me
taA
na
lysis
(P
JC
D v
ol 1
8
#1
)
15
.Eff
ica
cy a
nd
Sa
fety
of L
on
g-A
ctin
g B
eta
-Ag
on
ists
(LA
BA
) P
lus L
on
g-A
ctin
g M
usca
rin
ic A
nta
go
nis
ts
ve
rsu
s L
AB
A P
lus In
ha
led
Cort
ico
ste
roid
s in
Ch
ron
ic
Ob
str
uctive
Pu
lmo
na
ry D
ise
ase
: A
Me
ta-A
na
lysis
(PJC
D v
ol 1
8 #
1)
16
.A C
om
pa
rative
Stu
dy o
n P
ulm
on
ary
Fu
nctio
n T
est
resu
lts b
etw
ee
n m
orr
is a
nd
th
e F
ilip
ino
Sta
nd
ard
s
17
.Asso
cia
tio
n b
etw
ee
n T
um
or
Ne
cro
sis
Fa
cto
r-α
-
30
8G
/A P
oly
mo
rph
ism
an
d C
hro
nic
Ob
str
uctive
Pu
lmo
na
ry D
ise
ase
in
Pa
tie
nts
of th
e U
niv
ers
ity o
f
Sa
nto
To
ma
s H
osp
ita
0 (
PJC
D v
ol 1
7 #
3)
18
.No
rma
l S
tan
da
rds fo
r V
en
tila
tory
Fu
nctio
n te
st in
Ad
ult F
ilip
ino
s
Vol. 19 | Issue 03 | September 2018 32
N 18
11
7
7,2
02
63
15
9
35
PO
PU
LA
TIO
N
Po
st T
B t
rea
ted
pa
tie
nts
se
en
in M
DH
, w
ith
PF
T
Se
nio
r m
ed
ica
l re
sid
en
ts
20
ye
ars
old
an
d a
bo
ve
asth
ma
pa
tie
nts
pa
tie
nts
dia
gn
ose
d w
ith
Asth
ma
or
CO
PD
CO
PD
pa
tie
nts
CO
PD
pa
tie
nts
in
PH
C
SP
EC
IFIC
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
co
ho
rt
Pro
sp
ective
co
ho
rt
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
Ch
ron
ic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
TIT
LE
(R
efe
ren
ce
)
19
.Air
flo
w o
bstr
uctio
n a
mo
ng
pre
vio
usly
tre
ate
d
pu
lmo
na
ry tu
be
rcu
losis
no
nsm
oke
rs in
Ma
nila
Docto
rs H
osp
ita
l (P
JC
D v
ol 1
9 #
1)
20
.Kn
ow
led
ge
an
d U
se
of S
pir
om
etr
y fo
r th
e
Dia
gn
osis
of C
hro
nic
Ob
str
uctive
Pu
lmo
na
ry D
ise
ase
Am
on
g S
en
ior
Me
dic
al R
esid
en
ts in
Me
tro
Ma
nila
(PJC
D v
ol 1
8 #
1)
21
.Pre
va
len
ce
of A
sth
ma
Am
on
g F
ilip
ino
Ad
ults
ba
se
d o
n th
e N
atio
na
l a
nd
Hea
lth
Su
rve
y (
NN
HeS
)
(PJIM
vo
l 5
2 #
4)
22
.Pre
va
len
ce
of A
sth
ma
-CO
PD
Ove
rla
p S
yn
dro
me
(AC
OS
) A
mo
ng
Pa
tie
nts
Pre
se
ntin
g w
ith
Asth
ma
of
CO
PD
in
th
e O
PD
of th
e U
P-P
GH
Se
ctio
n o
f
Pu
lmo
na
ry M
ed
icin
e: A
Pilo
t S
tud
y (
PJC
D v
ol 1
8 #
1)
23
.Pre
dic
tive
Eq
ua
tio
n o
f Im
pu
lse
Oscill
om
etr
y (
IOS
)
Pa
ram
ete
rs in
Mid
dle
an
d A
dva
nce
d A
ge
Ad
ults w
ith
an
d w
ith
ou
t O
bstr
uctive
Lu
ng
Dis
ea
se
(P
JC
D v
ol 1
9
#1
)
24
.Asse
ssm
en
t o
f in
ha
latio
na
l te
ch
niq
ue
am
on
g a
du
lt
pa
tie
nt w
ith
ob
str
uctive
air
wa
y d
ise
ase
at th
e
ou
tpa
tie
nt d
ep
art
me
nt o
f a
te
rtia
ry le
ve
l h
osp
ita
l in
th
e
Ph
ilip
pin
es (
PJC
D v
ol 1
9 #
1)
25
.Asso
cia
tio
n o
f S
eru
m U
ric A
cid
Le
ve
ls a
nd
Ou
tco
me
s o
f P
atie
nts
with
Chro
nic
Ob
str
uctive
Pu
lmo
na
ry D
ise
ase
: A
Pro
sp
ective
Coh
ort
Stu
dy
(PJC
D v
ol 1
8 #
1)
26
.Co
rre
latio
n o
f F
ractio
na
l Exh
ale
d N
itri
c O
xid
e
Le
ve
l w
ith
Se
ve
rity
of C
hro
nic
Ob
str
uctive
Pu
lmo
na
ry
Dis
ea
se
(P
JC
D v
ol 1
8 #
1)
Philipp J Chest Dis 201833
N
20
3
89
59
80
25
2
13
5
40
8
11
PO
PU
LA
TIO
N
AE
CO
PD
pa
tie
nts
se
en
in
VM
MC
ER
CO
PD
pa
tie
nts
CO
PD
& b
ron
ch
iecta
sis
pa
tie
nts
CO
PD
pa
tie
nts
in
PH
C
Asth
ma
pa
tie
nt in
LC
P c
linic
CO
PD
pa
tie
nts
CO
PD
pa
tie
nts
se
en
at L
CP
OP
D t
akin
g IC
S/L
AB
A
AE
CO
PD
pa
tie
nts
fro
m M
arc
h
20
14
-Ju
n 2
01
5
pa
tie
nts
wh
o u
nd
erw
en
t C
P
exe
rcis
e te
st p
rio
r to
su
rge
ry
wh
ere
in (
Ja
nu
ary
20
13
to
Ap
ril
20
17
at
SL
MC
-QC
; A
pri
l 2
01
5
to A
pri
l 2
01
7 a
t S
LM
C-G
C
SP
EC
IFIC
Pro
sp
ective
co
ho
rt
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
cro
ss-
se
ctio
na
l
Retr
osp
ective
Retr
osp
ective
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
Ch
ron
ic
Air
wa
y
Dis
ea
se
Chro
nic
Air
wa
y
Dis
ea
se
TIT
LE
(R
efe
ren
ce
)
27
.Va
lida
tio
n o
f th
e O
tta
wa
ris
k s
ca
le in
id
en
tify
ing
CO
PD
in
exa
ce
rba
tio
n p
atie
nts
se
en
in
th
e
em
erg
en
cy d
ep
art
me
nt a
t ri
sk o
f se
rio
us a
dve
rse
eve
nt (P
JC
D v
ol 1
9 #
1)
28
.Blo
od
Eo
sin
op
hili
a a
s P
red
icto
r fo
r P
atie
nt
Ou
tco
me
s in
Ch
ron
ic O
bstr
uctive
Pu
lmo
na
ry D
ise
ase
(PJC
D v
ol 1
8 #
1)
29
.Th
e a
ccu
racy o
f B
ron
ko
Te
st in
de
tectin
g b
acte
ria
l
infe
ctio
n in
pa
tie
nts
with
ch
ron
ic lu
ng
dis
ea
se
s (
PJC
D
vo
l 1
7 #
2)
30
.Th
e a
sso
cia
tion
be
twe
en
th
e le
ve
l o
f C
OP
D
se
ve
rity
an
d h
yp
eri
nfla
tio
n (
PJC
D v
ol 1
7 #
2)
31
.Ph
en
oty
pin
g o
f A
du
lt P
atie
nts
with
Bro
nch
ial
Asth
ma
at th
e L
un
g C
en
ter
of th
e P
hili
pp
ine
s O
PD
Asth
ma
Clin
ic: A
6-m
on
th P
ilot S
tud
y (
PJC
D v
ol 1
7
#4
)
32
.Pre
va
len
ce
of d
ep
ressio
n a
mo
ng
CO
PD
pa
tie
nts
in V
ete
ran
s M
em
ori
al M
ed
ica
l C
en
ter
(PJC
D v
ol 1
7
#2
)
33
.Scre
en
ing
fo
r O
ste
op
oro
sis
in M
ale
Ch
ron
ic
Ob
str
uctive
Pu
lmo
na
ry D
ise
ase
Pa
tie
nts
on
Lo
ng
-
term
IC
S U
se
vs N
on
-IC
S U
se
rs a
t th
e O
PD
of
the
Lu
ng
Cen
ter
of
the
Ph
ilip
pin
es (
PJC
D V
ol 1
9 #
1 J
an
-
Ma
r 2
01
8)
34
.Utilit
y o
f D
EC
AF
sco
re in
Hosp
ita
lize
d P
atie
nts
with
CO
PD
in
Acu
te E
xa
ce
rba
tio
n (
PJC
D v
ol 1
8 #
1)
35
.Re
latio
nship
of
pre
-op
era
tive
ca
rdio
pu
lmo
na
ry
exe
rcis
e te
stin
g w
ith
in
-ho
sp
ita
l ou
tco
me
s a
nd
le
ng
th
of sta
y o
f p
atie
nts
wh
o u
nd
erw
en
t m
ajo
r su
rge
ry in
a
tert
iary
ho
sp
ita
l in
th
e P
hili
pp
ine
s: A
de
scri
ptive
ca
se
se
rie
s s
tud
y (
PJC
D v
ol 1
9 #
1)
Vol. 19 | Issue 03 | September 2018 34
N
20
4
43
10
7
39
27
10
0
71
9
PO
PU
LA
TIO
N
Dia
gn
ose
d C
OP
D p
atie
nts
in
UP
-PG
H,
UP
HD
MC
, Q
MM
C
Ad
ult p
atie
nts
ad
mitte
d a
t th
e
cri
tica
l ca
re u
nits in
SL
MC
Ad
ult p
atie
nts
ad
mitte
d in
IC
U
ICU
pa
tie
nts
in V
ete
rna
ns
Hosp
ita
l w
ith
de
liriu
m
AR
DS
Pa
tie
nts
in
US
T
Ho
sp
ita
l fr
om
Ja
n 2
01
2-
De
c
20
15
UP
PG
H p
atie
nts
with
SV
CO
Ad
ult p
atie
nts
se
en
at
the
LC
P
OS
A p
atie
nts
se
en
in
SL
MC
Sle
ep
Ce
nte
r w
ith
Be
rlin
Fle
mo
n a
nd
SL
MC
OS
AC
S
qu
estio
nn
aire
SP
EC
IFIC
Su
rve
y
Cro
ss-
se
ctio
na
l
Cro
ss-
se
ctio
na
l
Pro
sp
ective
Re
tro
sp
ective
Retr
osp
ective
Re
tro
sp
ective
Retr
osp
ective
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Descri
ptive
Descri
ptive
Descri
ptive
De
scri
ptive
Descri
ptive
De
scri
ptive
Descri
ptive
CL
US
TE
R
Chro
nic
Air
wa
y
Dis
ea
se
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Ca
re/V
asc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Ca
re/V
asc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
TIT
LE
(R
efe
ren
ce
)
36
.Pre
va
len
ce
of A
nxie
ty a
nd
Dep
ressio
n a
mo
ng
Fili
pin
o P
atie
nts
with
Ch
ron
ic O
bstr
uctive
Pu
lmo
na
ry
Dis
ea
se
: A
Mu
lti-
Cen
ter
Stu
dy (
PJIM
Vo
l 5
3 #
1)
37
.De
term
ina
tio
n o
f th
e e
nd
otr
ach
ea
l cu
ff p
ressu
re
tim
e-d
eca
y u
sin
g a
co
ntin
uo
us p
ressu
re m
on
ito
rin
g
de
vic
e (
PJC
D V
ol 1
6 #
1, Ja
n-M
ar
20
15
)
38
.Pre
va
len
ce
of d
elir
ium
in
pa
tie
nts
ad
mitte
d a
t
inte
nsiv
e c
are
un
its o
f P
GH
(P
JC
D V
ol 1
6 #
3, Ju
l-
Se
pt 2
01
5)
39
.Ne
uro
co
gn
itiv
e o
utc
om
e o
f p
atie
nts
with
de
liriu
m
in th
e in
ten
siv
e c
are
un
its a
t a
te
rtia
ry g
ove
rnm
en
t
ho
sp
ita
l (P
JC
D v
ol 1
8 #
2)
40
.Oxyg
en
Sa
tura
tio
n In
de
x a
s a
Su
rro
ga
te o
f
Pa
O2
/FiO
2 R
atio
in
Acu
te R
esp
ira
tory
Dis
tre
ss
Syn
dro
me
(P
JC
D v
ol 1
8 #
2 )
41
.Tre
atm
en
t o
utc
om
es o
f p
atie
nts
with
SV
C
syn
dro
me
wh
o r
ece
ive
d h
igh
-do
se
RT
at
UP
PG
H
fro
m 2
00
9-2
01
1 (
Acta
Me
dic
a P
hili
pp
ina
Vo
l 4
7 #
3,
20
13
)
42
.Th
ree
-ye
ar
revie
w o
f p
atie
nts
dia
gn
ose
d w
ith
Ob
str
uctive
Sle
ep
Ap
ne
a in
th
e L
CP
(P
JC
M V
ol 1
6
#2
, A
pri
l-Ju
ne
20
15
)
43
.Dia
gn
ostic A
ccu
racy o
f B
erl
in,
Fle
mo
ns
Sle
ep
Ap
ne
a C
linic
al S
co
re a
nd
St.
Lu
ke
’s M
ed
ica
l C
en
ter–
Ob
str
uctive
Sle
ep
Ap
ne
a C
linic
al S
co
re
Qu
estio
nn
air
es fo
r S
cre
en
ing
Ob
str
uctive
Sle
ep
Ap
ne
a in
Fili
pin
o P
atie
nts
(P
JC
D V
ol 1
8 #
4 O
ct-
Dec
20
17
)
Philipp J Chest Dis 201835
N 84
56
45
23
5
20
(ctr
l)
vs 5
5
(in
terv
en
tio
n)
41
13
3
PO
PU
LA
TIO
N
ICU
pa
tie
nts
re
ferr
ed
an
d n
ot
refe
rre
d to
clin
ica
lnu
trtio
n
Me
dic
al re
sid
en
ts in
PG
H
Nurs
es w
ith
in
tub
ate
d p
atie
nts
in IC
U o
f M
MC
Ju
n 2
01
6-D
ec
20
16
intu
ba
ted
pa
tie
nts
ad
mitte
d a
t
the
IC
U
Intu
ba
ted
pa
tie
nts
at th
e IC
U o
f
TM
C
Pa
tie
nts
of sp
ecia
l ca
re u
nits in
Cho
ng
Hu
a H
osp
ita
l
Ad
ult p
atie
nts
at th
e C
EN
ICU
an
d M
ICU
LC
P n
urs
es
SP
EC
IFIC
Retr
osp
ective
co
ho
rt
Su
rve
y
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
co
ho
rt
Coh
ort
Cro
ss-
se
ctio
na
l
ST
UD
Y
DE
SIG
N
Descri
ptive
Descri
ptive
Descri
ptive
Inte
rve
ntio
na
l
Inte
rve
ntio
na
l
Inte
rve
ntio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
TIT
LE
(R
efe
ren
ce
)
44
.Clin
ica
l Ou
tco
me
s o
f M
ech
an
ica
lly V
en
tila
ted
Pa
tie
nts
in
th
e In
ten
siv
e C
are
Unit R
efe
rre
d to
Clin
ica
l Nutr
itio
n S
erv
ice
s (
PJC
D v
ol 1
8 #
1)
45
.A s
urv
ey o
f p
ractice
pa
tte
rns o
f m
ed
ica
l re
sid
en
ts
on
th
e u
se
of n
on
-in
va
siv
e v
en
tila
tio
n a
t P
GH
(P
JC
D
Vo
l 1
6 #
3, Ju
l-S
ep
t 2
01
5)
46
.Ad
he
ren
ce
, E
na
ble
rs a
nd
Ba
rrie
rs to
th
e
Imp
lem
en
tatio
n o
f th
e V
en
tila
tor-
Asso
cia
ted
Pn
eu
mo
nia
Bu
nd
le in
th
e In
ten
siv
e C
are
Un
its a
t th
e
Ma
ka
ti M
ed
ica
l C
en
ter
(PJC
D v
ol 1
9 #
1)
47
.Th
e e
ffe
ct o
f w
he
y p
rote
in s
up
ple
me
nta
tio
n o
n
du
ratio
n o
f m
ech
an
ical v
en
tila
tio
n
48
.Th
e A
sso
cia
tio
n b
etw
ee
n Im
ple
me
nta
tion
of
Bu
nd
les o
f C
are
an
d P
ossib
le V
en
tila
tor
Asso
cia
ted
Pn
eu
mo
nia
Am
on
g M
ech
an
ica
lly V
en
tila
ted
Pa
tie
nts
in th
e In
ten
siv
e C
are
Un
it: A
Qu
asi-
Exp
eri
me
nta
l
Stu
dy (
PJC
D v
ol 1
8 #
1)
49
.A c
om
pa
riso
n o
f th
e c
linic
al o
utc
om
e o
f th
e n
ew
en
tera
l fe
ed
ing
pro
toco
l ve
rsu
s tra
ditio
na
l en
tera
l
fee
din
g a
mo
ng
cri
tica
lly-i
ll p
atie
nts
ad
mitte
d a
t C
ho
ng
Hua
Hosp
ita
l S
pe
cia
l C
are
Unit (
PJC
D V
ol 1
6 #
3, Ju
l-
Se
pt 2
01
5)
50
.Obse
rva
tio
na
l stu
dy o
n t
he
cu
rre
nt w
ea
nin
g
pra
ctice
s in
th
e c
en
tra
l in
ten
siv
e c
are
an
d m
ed
ica
l
inte
nsiv
e c
are
un
its o
f th
e P
GH
(P
JC
D V
ol 1
6 #
3, Ju
l-
Se
pt 2
01
5)
51
.Pre
va
len
ce
an
d c
on
se
qu
ence
s o
f sh
ift w
ork
dis
ord
er
am
on
g n
urs
es a
t L
CP
(P
JC
M V
ol 1
6 #
2,
Ap
ril-
Ju
ne
20
15
)
Vol. 19 | Issue 03 | September 2018 36
N
15
6
36
20
29
0
PO
PU
LA
TIO
N
Bu
s d
rive
rs o
f co
mp
an
ies w
ith
sta
tio
ns in
QC
20
stu
die
s
Nurs
es w
ith
in
tub
ate
d p
atie
nts
in IC
U o
f M
MC
Ju
n 2
01
6-D
ec
20
16
pa
tie
nts
ad
mitte
d in
MIC
U o
f
PG
H
cri
tica
lly il
l in
tub
ate
d p
atie
nts
in
SL
MC
an
d d
ete
rmin
ation
of
RS
Bi
intu
ba
ted
pa
tie
nts
ad
mitte
d a
t
the
IC
U o
f P
HC
SP
EC
IFIC
Cro
ss-
se
ctio
na
l
Me
ta-a
na
lysis
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
co
ho
rt
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Ca
re/V
asc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
TIT
LE
(R
efe
ren
ce
)
52
.Pre
va
len
ce
of O
SA
sym
pto
ms a
nd
exce
ssiv
e
da
ytim
e s
lee
pin
ess a
mo
ng
co
mm
erc
ial l
on
g-d
ista
nce
bu
s d
rive
rs in
th
e P
hili
pp
ine
s (
PJC
M V
ol 1
6 #
2, A
pri
l-
Ju
ne
20
15
)
53
.No
n-i
nva
siv
e V
en
tila
tio
n v
ers
us C
on
ve
ntio
na
l
Oxyg
en
Th
era
py in
Im
mu
no
-co
mpro
mis
ed
Pa
tie
nts
: A
Me
ta-a
na
lysis
(P
JC
D v
ol 1
8 #
1)
54
.Th
e A
sso
cia
tio
n b
etw
ee
n Im
ple
me
nta
tion
of
Bu
nd
les o
f C
are
an
d P
ossib
le V
en
tila
tor
Asso
cia
ted
Pn
eu
mo
nia
Am
on
g M
ech
an
ica
lly V
en
tila
ted
Pa
tie
nts
in th
e In
ten
siv
e C
are
Unit: A
Qu
asi-
Exp
eri
me
nta
l
Stu
dy (
PJC
D v
ol 1
8 #
1)
55
.A P
relim
ina
ry S
tud
y o
n th
e N
utr
itio
na
l In
take
an
d
Clin
ica
l Ou
tco
me
s o
f P
atie
nts
Ad
mitte
d a
t th
e M
ed
ica
l
Inte
nsiv
e C
are
Unit (
PJC
D v
ol 1
8 #
1)
56
.De
ve
lop
me
nt o
f a
va
lida
ted
qu
estio
nn
air
e to
de
term
ine
th
e K
no
wle
dg
e, A
ttitu
de
an
d P
ractice
s o
f
Inte
rnis
ts in
de
term
inin
g p
atie
nt’s r
ea
din
ess fo
r
we
an
ing
an
d d
isco
ntin
ua
tio
n fro
m v
en
tila
tory
su
pp
ort
57
.A C
om
pa
rative
Stu
dy o
n th
e D
iap
hra
gm
Mu
scle
Th
ickn
ess a
nd
Rap
id S
ha
llow
Bre
ath
ing
In
de
x (
RS
BI)
as a
pre
dic
tor
for
su
cce
ssfu
l extu
ba
tio
n a
mo
ng
cri
tica
lly il
l a
du
lt p
atie
nts
(P
JC
D v
ol 1
9 #
1 J
an
-Ma
r
20
18
)
58
.Accu
racy o
f G
as E
xch
an
ge
Me
asu
rem
en
ts a
s
Pre
dic
tors
Of
Ea
rly S
ucce
ssfu
l We
anin
g A
mo
ng
IC
U
Pa
tie
nts
of P
hili
pp
ine
Hea
rt C
en
ter:
A P
rosp
ective
Coh
ort
Stu
dy (
PJC
D v
ol 1
9 #
1)
Philipp J Chest Dis 201837
N
14
42
52
/48
52
76
17
1
20
2
52
PO
PU
LA
TIO
N
Me
ch
an
ica
ll ve
ntila
ted
pa
tie
nts
in M
DH
(V
AP
bu
nd
le
gro
up
Ap
ril-
Se
p 2
01
6)
&
ba
se
line
gro
up
(S
ep
20
14
-Fe
b
20
15
)
pa
tie
nts
ad
mitte
d in
US
TH
IC
U
(De
c 2
01
3-M
ar
20
14
)
Pa
tie
nts
at U
ST
H
PS
G s
tud
ies th
rou
gh
Resp
ica
re
Pa
tie
nts
se
en
at th
e S
lee
p L
ab
of L
CP
fem
ale
pa
tie
nts
in S
LM
C w
ith
pri
ma
ry lu
ng
ca
SP
EC
IFIC
Pro
sp
ective
co
ho
rt
Case
co
ntr
ol
Retr
osp
ective
Retr
osp
ective
Retr
osp
ective
Su
rve
y
Cro
ss-
se
ctio
na
l
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Descri
ptive
CL
US
TE
R
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
Cri
tica
l
Care
/Va
sc
ula
r/S
lee
p
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
TIT
LE
(R
efe
ren
ce
)
59
.Co
nco
rda
nce
of In
cid
en
ce
of P
osto
pe
rative
Pu
lmo
na
ry C
om
plic
atio
ns w
ith
Pre
dic
ted
Pro
ba
bili
ties
Usin
g M
ultifa
cto
ria
l R
isk In
de
x f
or
Po
sto
pe
rative
Pn
eu
mo
nia
an
d R
esp
ira
tory
Fa
ilure
at th
e V
ete
ran
s
Me
mo
ria
l M
ed
ica
l C
en
ter
60
.Th
e E
ffic
acy o
f th
e V
en
tila
tor
Bu
nd
le in
Pre
ve
ntin
g
Ve
ntila
tor-
Associa
ted P
ne
um
on
ia a
mo
ng
IC
U
Pa
tie
nts
in
th
e M
an
ila D
octo
rs H
osp
ita
l (P
JC
D v
ol 1
9
#1
)
61
.Asse
ssm
en
t o
f ri
sk fo
r V
TE
an
d V
TE
pro
ph
yla
xis
ba
se
d o
n th
e T
hro
mb
osis
Ris
k A
sse
ssm
en
t F
orm
fo
r
Me
dic
al a
nd
Su
rgic
al P
atie
nts
am
on
g IC
U p
atie
nt
(PJC
D v
ol 1
7 #
2)
62
.Pre
dic
tors
of
failu
re a
mo
ng
pa
tie
nts
giv
en
no
n-
inva
siv
e m
ech
an
ica
l ve
ntila
tio
n a
t th
e U
ST
Hosp
ita
l
(PJC
D V
ol 1
6 #
1, Ja
n-M
ar
20
15
)
63
.Ad
juste
d n
eck c
ircu
mfe
rence
sco
re, S
TO
P B
AN
G,
an
d B
erl
in q
ue
stio
nn
air
e a
s s
cre
en
ing
to
ols
fo
r O
SA
(PJC
M V
ol 1
6 #
2, A
pri
l-Ju
ne
20
15
)
64
.A s
urv
ey o
f kn
ow
led
ge
, a
ttitu
de
s a
nd
pra
ctice
s o
f
se
da
tio
n a
nd
an
alg
esia
am
on
g m
ed
ica
l re
sid
en
ts a
nd
pu
lmo
na
ry fe
llow
s in
tra
inin
g a
t th
e U
niv
ers
ity o
f th
e
Ph
ilip
pin
es G
en
era
l H
osp
ita
l (P
JC
D v
ol 1
8 #
1)
65
.De
ve
lop
me
nt a
nd
va
lida
tio
n o
f a
pre
dic
tive
fo
rmu
la
for
op
tim
al C
PA
P le
ve
l in
Fili
pin
o p
atie
nts
with
OS
A
se
en
in
LC
P (
PJC
D V
ol 1
6 #
2, A
pri
l-Ju
ne
20
15
)
66
.Clin
ica
l Pro
file
s a
nd
Su
rviv
al o
f F
em
ale
Pa
tie
nts
Dia
gn
ose
d w
ith
Pri
ma
ry L
un
g C
an
ce
r R
eg
iste
red
at
the
Lu
ng
Can
ce
r R
eg
istr
y o
f S
t. L
uke
’s M
ed
ica
l
Cen
ter
Vol. 19 | Issue 03 | September 2018 38
N
31
2
26
25
1
77
00
98
13
33
11
2
PO
PU
LA
TIO
N
Lu
ng
Ca
nce
r p
atie
nts
in L
CP
ad
mitte
d fo
r p
ne
um
on
ia
EB
US
pro
ce
du
re d
on
e in
TM
C
Ja
n 2
01
5-D
ec 2
01
5)
Pa
tie
nts
ad
mitte
d a
t a
te
rtia
ry
ho
sp
ita
l (2
01
1-2
01
3)
with
a
his
tolo
gic
/ cyto
log
ic d
iag
no
sis
of p
rim
ary
lu
ng
ca
nce
r
Fili
pin
o a
du
lts in
17
re
gio
ns
pa
tie
nts
in V
MM
C w
ith
ma
lign
an
t p
leu
ral e
ffu
sio
n
10
stu
die
s th
at in
vo
lve
pa
tie
nts
with
in
dw
elli
ng
ca
the
ters
Pa
tie
nts
wh
o u
nd
erw
en
t
bro
nch
oscop
u s
usp
ecte
d fo
r
ma
lign
an
cy
SP
EC
IFIC
Retr
osp
ective
Retr
osp
ective
Retr
osp
ective
Su
rve
y
Am
bis
pe
ctive
co
ho
rt
Me
ta-a
na
lysis
Pro
sp
ective
Pro
sp
ective
cro
ss-
se
ctio
na
l
ST
UD
Y
DE
SIG
N
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
TIT
LE
(R
efe
ren
ce
)
67
.Clin
ica
l Pro
file
an
d O
utc
om
e o
f L
un
g C
an
ce
r
Pa
tie
nts
with
Pn
eu
mo
nia
Ad
mitte
d a
t L
un
g C
en
ter
of
the
Ph
ilip
pin
es: A
5-y
ea
r R
etr
osp
ective
Stu
dy (
PJC
D
vo
l 1
8 #
3)
68
.En
do
bro
nchia
l Ultra
so
un
d-G
uid
ed T
ran
sb
ron
ch
ial
Nee
dle
Asp
ira
tio
n in
th
e P
hili
pp
ine
s: A
Pre
limin
ary
Retr
osp
ective
Coh
ort
Stu
dy o
n D
iag
no
stic
Pe
rfo
rma
nce
(P
JC
D v
ol 1
7 #
3)
69
.A R
etr
osp
ective
Stu
dy C
om
pa
rin
g Y
ou
ng
an
d O
ld
Pa
tie
nts
Dia
gn
ose
d w
ith
Pri
ma
ry L
un
g C
an
ce
r (P
JC
D
vo
l 1
8 #
2)
70
.Sm
okin
g b
urd
en
in
th
e P
hili
pp
ine
s (
Acta
Me
dic
a
Ph
ilip
pin
a V
ol 4
7 #
3, 2
01
3)
71
.LE
NT
Pro
gn
ostic S
co
re in
Ma
lign
an
t P
leu
ral
Eff
usio
n a
t V
ete
ran
s M
em
ori
al M
ed
ica
l C
en
ter
(PJC
D
vo
l 1
8 #
1)
72
.A M
eta
-an
aly
sis
on
In
dw
elli
ng
Ple
ura
l C
ath
ete
rs
vs P
leu
rod
esis
in th
e M
an
ag
em
en
t o
f M
alig
na
nt
Ple
ura
l E
ffu
sio
ns: A
Mo
de
rn D
ilem
ma
(P
JC
D v
ol 1
9
#1
)
73
.Na
tio
na
l Sm
okin
g P
reva
len
ce
Stu
dy (
PJIM
vo
l 5
1
#1
)
74
.Co
mp
ara
bili
ty o
f A
uto
ma
ted
Qu
an
tita
tive
Im
ag
e
Cyto
me
try (
Cle
arC
yte
TM
) R
esu
lts o
f B
ron
ch
ial
Wash
ing
s w
ith
Ma
nu
al C
yto
log
y a
nd
His
top
ath
olo
gy
in th
e D
iag
no
sis
of L
un
g C
an
ce
r (P
JC
D v
ol 1
9 #
1)
Philipp J Chest Dis 201839
N 88
10
0
21
2
15
9
17
96
16
1
50
8
PO
PU
LA
TIO
N
Case
re
vie
w o
f p
atie
nts
with
MP
E in
CG
H
pa
tie
nt in
VM
MS
with
ma
lign
an
t p
leu
ral e
ffu
sio
n
UP
Ma
nila
stu
de
nts
ag
ed
18
-
24
Su
sp
ecte
d M
DR
TB
ca
se
s
sta
rte
d o
n S
TR
at th
e L
CP
MD
RT
B p
atie
nts
All
pa
tie
nts
co
mp
lete
d C
atI
tre
atm
en
t a
t L
CP
Ad
ult p
atie
nts
in V
MM
C w
ith
co
ug
h o
f le
ss th
an
2 w
ee
ks
SS
P a
nd
Tb
pa
tie
nts
ad
mitte
d
in L
CP
ja
n 2
00
4 to
De
c 2
01
3
SP
EC
IFIC
Retr
osp
ective
Retr
osp
ective
Am
bis
pe
ctive
co
ho
rt
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
cro
ss-
se
ctio
na
l
Retr
osp
ective
co
ho
rt
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
CL
US
TE
R
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
ILD
/Ma
lign
an
cy/S
mo
ki
ng
/Air
Po
llutio
n
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
TIT
LE
(R
efe
ren
ce
)
75
.Pro
gn
ostic u
tilit
y o
f th
e L
EN
T S
co
re in
Pre
dic
tin
g
Su
rviv
al a
mo
ng
Pa
tie
nts
with
Ma
lign
an
t P
leu
ral
Eff
usio
n a
dm
itte
d a
t th
e C
hin
ese
Ge
ne
ral H
osp
ita
l
an
d M
ed
ica
l C
en
ter:
A C
oh
ort
Stu
dy (
PJC
D v
ol 1
9
#1
)
76
.Va
lidity o
f th
e L
EN
T P
rog
no
stic S
co
re fo
r
Pre
dic
tin
g S
urv
iva
l in
Ma
lign
an
t P
leu
ral E
ffu
sio
n
(PJC
D v
ol 1
8 #
1)
77
.Eva
lua
tio
n fo
r cig
are
tte
s a
mo
ng
UP
Ma
nila
stu
de
nts
th
rou
gh
sta
ted
pre
fere
nce
me
tho
ds (
Acta
Me
dic
a P
hili
pp
ina
Vo
l 4
8 #
3, 2
01
4)
78
.Tre
atm
en
t o
utc
om
e o
f p
atie
nts
pre
vio
usly
sta
rte
d
on
sta
nd
ard
ize
d tre
atm
en
t re
gim
en
fo
r su
sp
ecte
d
MD
R-T
B a
t th
e L
CP
: P
MD
T (
PJC
D V
ol 1
6 #
4, O
ct-
Dec 2
01
5)
79
.Ou
tco
me
s o
f M
ulti D
rug
Re
sis
tan
t T
ub
erc
ulo
sis
Con
tacts
wh
o r
ece
ive
d C
ate
go
ry I T
rea
tme
nt fo
r
Clin
ica
lly D
iag
no
se
d P
ulm
on
ary
Tu
be
rcu
losis
un
de
r
DO
TS
80
.Pre
va
len
ce
of p
ulm
on
ary
im
pa
irm
en
t a
fte
r
tre
atm
en
t o
f p
ulm
on
ary
tu
be
rcu
losis
am
on
g p
atie
nts
tre
ate
d a
t th
e L
CP
81
.Pre
dic
tio
n o
f P
ne
um
on
ia B
ase
d o
n S
ign
s a
nd
Sym
pto
ms in
Pa
tie
nts
Pre
se
ntin
g w
ith
Co
ug
h a
t th
e
Ve
tera
ns M
em
ori
al M
ed
ica
l C
en
ter
(PJC
D v
ol 1
8 #
2)
82
.Ris
k F
acto
rs fo
r D
eve
lop
me
nt o
f S
eco
nd
ary
Sp
on
tan
eo
us P
ne
um
oth
ora
x in
Pa
tie
nts
with
Pu
lmo
na
ry T
ub
erc
ulo
sis
Ad
mitte
d to
th
e L
un
g C
en
ter
of th
e P
hili
pp
ine
s: A
10
-ye
ar
Exp
eri
en
ce
(P
JC
D v
ol
18
#1
)
Vol. 19 | Issue 03 | September 2018 40
N
12
4
63
18
4
83
15
3
15
3
16
4
PO
PU
LA
TIO
N
ICU
pa
tie
nts
in C
ho
ng
Hu
a
Hosp
ita
l
Lu
ng
Ca
nce
r p
atie
nts
in
Ve
tera
ns H
osp
ita
l with
PT
B
dia
gn
osis
PT
B p
atie
nts
re
gis
tere
d u
nd
er
DO
TS
in
Bin
an
an
d C
ab
uya
o,
La
gu
na
pa
tie
nts
dia
gn
ose
d w
ith
HIV
with
pu
lmo
na
ry p
rese
nta
tio
n
fro
m ja
n 2
00
0 to
Se
p 2
01
5
ne
ga
tive
sm
ea
r P
TB
re
ferr
ed
to U
ST
H T
BD
C
Neg
ative
-sm
ea
r P
TB
pa
tie
nts
refe
rre
d to
US
TH
-TB
DC
fro
m
Ja
n 2
01
4to
De
c 2
01
4
Ad
mitte
d p
atie
nts
at th
e L
CP
SP
EC
IFIC
Retr
osp
ective
Retr
osp
ective
cro
ss-
se
ctio
na
l
Su
rve
y
Cro
ss-
se
ctio
na
l
Retr
osp
ective
Retr
osp
ective
Retr
osp
ective
ST
UD
Y
DE
SIG
N
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
Descri
ptive
CL
US
TE
R
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
TIT
LE
(R
efe
ren
ce
)
83
.Co
rre
latio
n o
f e
nd
otr
ach
ea
l asp
ira
te G
ram
sta
in
an
d fin
al cu
ltu
re r
esu
lts in
IC
U p
atie
nts
in a
te
rtia
ry
ho
sp
ita
l in
Ceb
u C
ity:
A r
etr
osp
ective
stu
dy (P
JC
D
Vo
l 1
6 #
4, O
ct-
Dec 2
01
5)
84
.Pre
va
len
ce
of tu
be
rcu
losis
infe
ctio
n in
ca
nce
r
pa
tie
nts
at
Ve
tera
ns M
em
ori
al M
ed
ica
l C
en
ter
(PJC
D
vo
l 1
8 #
2)
85
.So
cio
-co
gn
itiv
e fa
cto
rs a
nd
pe
rce
ive
d b
arr
iers
:
Th
eir
in
flu
en
ce
on
th
e p
atie
nt's
ad
he
ren
ce
to
PT
B
tre
atm
en
t (A
cta
Me
dic
aP
hili
pp
ina
Vo
l 4
8 #
3, 2
01
4)
86
.Asse
ssm
en
t o
f th
e U
tiliz
atio
n o
f G
en
e X
pe
rt
MT
B/R
IF in
Ph
ilip
pin
e T
ub
erc
ulo
sis
So
cie
ty, In
c
87
.Clin
ica
l Corr
ela
tio
n o
f A
bso
lute
To
tal L
ym
ph
ocyte
an
d C
D4
T-L
ym
ph
ocyte
Co
un
t w
ith
Pu
lmo
na
ry
Com
plic
atio
ns o
f H
um
an
Im
mu
no
de
ficie
ncy V
iru
s
(HIV
) S
ero
po
sitiv
e P
atie
nts
Se
en
at th
e L
un
g C
en
ter
of th
e P
hili
pp
ine
s (
PJC
D v
ol 1
7 #
4)
88
.Pe
rfo
rma
nce o
f T
B D
iag
no
stic C
om
mitte
e in
Cert
ifyin
g D
ise
ase
Activity o
f S
me
ar
Neg
ative
Cate
go
ry II C
ase
s in
Dis
tric
t IV
of M
an
ila
89
.Tu
rna
rou
nd
Tim
e f
or
Sm
ea
r-n
eg
ative
Ca
teg
ory
I
Case
s to
In
itia
tio
n o
f T
rea
tme
nt in
Dis
tric
t IV
of
Ma
nila
fro
m J
an
ua
ry 2
01
4 to
Dece
mb
er
20
14
(P
JC
D v
ol 1
8
#2
)
90
.A 1
3-y
ea
r re
tro
sp
ective
stu
dy o
n c
linic
al p
rofile
an
d m
an
ag
em
ent o
f p
atie
nts
ad
mitte
d fo
r p
ulm
on
ary
asp
erg
illo
ma
(P
JC
D V
ol 1
6 #
4, O
ct-
Dec 2
01
5)
Philipp J Chest Dis 201841
N
16
2
63
10
2
71
17
8
78
PO
PU
LA
TIO
N
Ad
mitte
d a
du
lt p
atie
nts
at
the
LC
P
pa
tie
nts
in L
CP
with
ple
ura
l
eff
usio
n,p
ost d
rain
ag
e
Ad
mitte
d p
atie
nts
at th
e L
CP
PT
B p
atie
nts
un
de
rgo
ing
tre
atm
en
fo
r C
at II
HIV
pa
tie
nts
co
-in
fecte
d w
ith
TB
en
rolle
d a
t th
e S
AG
IP U
nit
fro
m J
an
-De
c 2
01
4
Pa
tie
nts
ad
mitte
d a
t th
e w
ard
of P
GH
ICU
pa
tie
nts
in C
ho
ng
Hu
a
Hosp
ita
l
SP
EC
IFIC
Retr
osp
ective
Cro
ss-
se
ctio
na
l
Cro
ss-
se
ctio
na
l
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
Pro
sp
ective
ST
UD
Y
DE
SIG
N
Descri
ptive
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
CL
US
TE
R
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
TIT
LE
(R
efe
ren
ce
)
91
.A r
etr
osp
ective
stu
dy o
n th
e c
linic
al p
rofile
of
pa
tie
nts
with
se
co
nd
ary
sp
on
tan
eo
us p
ne
um
oth
ora
x,
with
co
exis
tin
g p
ulm
on
ary
tu
be
rcu
losis
at th
e L
CP
fro
m J
an
ua
ry 2
00
8 to
Dece
mb
er
20
12
(P
JC
D V
ol 1
6
#4
, O
ct-
Dec 2
01
5)
92
.Va
lidity o
f P
leu
ral F
luid
Cho
leste
rol in
Diffe
ren
tia
tin
g E
xu
da
tive
fro
m T
ran
su
da
tive
Ple
ura
l
Eff
usio
ns o
f P
leu
ral F
luid
Cho
leste
rol i
n
Diffe
ren
tia
tin
g E
xu
da
tive
fro
m T
ran
su
da
tive
Ple
ura
l
Eff
usio
ns (
PJC
D v
ol 1
8 #
1)
93
.Co
mp
ari
so
n o
f p
rese
psin
an
d p
roca
lcito
nin
as
bio
ma
rke
rs in
th
e d
iag
no
sis
of
se
psis
(P
JC
D V
ol 1
6
#4
, O
ct-
Dec 2
01
5)
94
.Co
mp
ara
tive
An
aly
sis
of G
en
eX
pe
rt M
TB
/RIF
Assa
y T
estin
g w
ith
MT
B C
ultu
re A
mo
ng
PT
B
Cate
go
ry II–
Tre
ate
d P
atie
nts
(P
JC
D v
ol 1
7 #
2)
95
.Ad
he
ren
ce
to
th
e N
atio
na
l T
ub
erc
ulo
sis
Co
ntr
ol
Pro
gra
m G
uid
elin
es 2
01
3 a
nd
Ou
tco
me
of T
rea
tme
nt
on
Pe
op
le L
ivin
g W
ith
HIV
Co
-In
fecte
d w
ith
Tu
be
rcu
losis
En
rolle
d in
th
e P
hili
pp
ine
Ge
ne
ral
Hosp
ita
l T
rea
tme
nt H
ub
(S
AG
IP)
(PJC
D v
ol 1
8 #
1)
96
.Clin
ica
l pro
file
an
d o
utc
om
e o
f S
ten
otr
op
ho
mo
na
s
ma
lto
ph
ilia in
fectio
ns a
mo
ng
Ad
ult p
atie
nts
Ad
mitte
d
at th
e U
niv
ers
ity o
f S
an
to T
om
as H
osp
ita
l: A
Se
ve
n
ye
ar
Re
tro
sp
ective
Stu
dy
97
.Eva
lua
tin
g th
e u
tilit
y o
f th
e C
AP
-PIR
O s
co
rin
g
syste
m in
ad
ult p
atie
nts
with
se
ve
re c
om
mu
nity-
acq
uir
ed
pn
eu
mo
nia
at C
ho
ng
Hua
Hosp
ita
l (P
JC
D
Vo
l 1
6 #
1, Ja
n-M
ar
20
15
)
98
.Sa
fety
an
d e
ffic
acy o
f C
efp
iro
me
am
on
g F
ilip
ino
Pa
tie
nts
Vol. 19 | Issue 03 | September 2018 42
N 27
10
98
60
52
27
PO
PU
LA
TIO
N
ad
ult T
B p
atie
nts
Ad
ult p
atie
nts
with
un
ilate
ral
ple
ura
l e
ffu
sio
n
ad
ult p
atie
nts
in
Ad
ult p
atie
nts
ad
mitte
d fo
r lu
ng
rese
ctio
n
SP
EC
IFIC
Pro
sp
ective
Pro
sp
ective
co
ho
rt
Retr
osp
ective
Retr
osp
ective
co
ho
rt
Retr
osp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
cro
ss-
se
ctio
na
l
Pro
sp
ective
co
ho
rt
ST
UD
Y
DE
SIG
N
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Ob
se
rva
tio
na
l
Descri
ptive
CL
US
TE
R
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Infe
ctio
us
Lu
ng
Dis
ea
se
s
Oth
ers
:
Pu
lmo
Reh
ab
Oth
ers
:
Nutr
itio
n
TIT
LE
(R
efe
ren
ce
)
99
.Th
e in
cid
en
ce
of M
yco
ba
cte
riu
m o
the
nth
an
Tu
be
rcu
losis
Iso
late
d in
sp
ecim
en
s S
usp
ecte
d o
f
Tu
be
rcu
losis
in a
Te
rtia
tyH
osp
ita
l in
th
e P
hili
pp
ine
s
10
0.S
cre
en
ing fo
r D
iab
ete
s M
elli
tus in
Pa
tie
nts
dia
gn
ose
d w
ith
Pu
lmo
na
ry T
ub
erc
ulo
sis
(P
JIM
vo
l 5
2
#4
)
10
1.F
irst L
ine
An
ti-t
ub
erc
ulo
sis
Dru
g R
esis
tan
ce
Pa
tte
rn in
Myco
ba
cte
riu
m tu
be
rcu
losis
iso
late
s a
t th
e
Univ
ers
ity o
f S
an
to T
om
as H
osp
ita
l fr
om
20
03
-20
13
10
2.I
mp
act o
f A
dh
ere
nce
to
th
e P
hili
pp
ine
Clin
ica
l
Pra
ctice
Gu
ide
line
s o
n th
e C
linic
al O
utc
om
es o
f
Pa
tie
nts
Ho
sp
ita
lize
d fo
r C
om
mu
nity-A
cq
uir
ed
Pn
eu
mo
nia
at th
e L
un
g C
en
ter
of th
e P
hili
pp
ine
s
(PJC
D v
ol 1
7 #
3)
10
3.V
alid
ity S
tud
y o
f G
en
e X
pe
rt M
TB
/RIF
Assa
y in
the
Dia
gn
osis
of T
ub
erc
ulo
us P
leu
ral E
ffu
sio
n a
mo
ng
Ad
ult a
tie
nts
at
the
Lu
ng
Cen
ter
of th
e P
hili
pp
ine
s
(PJC
D V
ol 1
8 #
4 O
ct-
Dec 2
01
7)
10
4.O
utc
om
e o
f P
atie
nts
Who
Und
erw
en
t
Pro
gra
mm
atic P
ulm
on
ary
Reh
ab
ilita
tion
Ve
rsu
s
Ince
ntive
Sp
iro
me
try A
lon
e A
fte
r L
un
g R
ese
ctive
Su
rge
ry: A
Pro
sp
ective
, O
bse
rva
tio
na
l, C
ross-
Se
ctio
na
l, P
ilot S
tud
y (
PJC
D v
ol 1
7 #
3)
10
5.P
re-o
pe
rative
Nutr
itio
na
l Asse
ssm
en
t in
Su
rgic
al
Lu
ng
Rese
ctio
n a
nd
Occu
rre
nce
of P
osto
pe
rative
Pu
lmo
na
ry C
om
plic
atio
n: A
Pro
sp
ective
Coh
ort
Stu
dy
(PJC
D v
ol 1
8 #
1)
Philipp J Chest Dis 201843
Appendix II. Revised guidelines on research grant applications
I. PCCP GUIDELINES FOR COUNCIL INITIATED/SUPPORTED RESEARCHES
A. Grant Eligibility
• In order to avoid any implication of conflict of interest, no member of a grant review committee
may submit a grant application. Those committee members who are mentioned in an application
or have written a letter of support must excuse themselves from the deliberations.
• A grant recipient/winner shall not be allowed to apply for the same PCCP or industry sponsored
grant within a period of five years. Grant recipients may apply for a different grant.
B. Grant Application
• Submission by the grant applicant of a description of the project to be funded should be in
sufficient detail
• A written confirmation by the grant applicant to use grant funds solely for purposes of the project
described in the application and to return any unspent funds or any funds that are spent for an
improper purpose shall be submitted.
C. Receipt of Proposal
• As proposals are received, they will be added to a grant list with the following information: author,
PCCP council, title, primary reviewer, secondary reviewer.
• Proposals must contain the endorsement of the Council Chair with the approval of a majority its
members during one its meetings (50% of attendees plus one with the total number achieving a
quorum). Electronic approval through the internet or SMS are also acceptable alternatives.
• Proposals must be submitted for review by an Institutional Review Board (IRB) / Ethics
Committee.
• The Research Committee Chair will forward it to the Grants Unit where a primary and secondary
reviewer will be assigned to each grant.
• After proposals are received, PCCP staff will send the following information to each reviewer:
o Copy of the proposals assigned to them by the Research Committee Chair. A committee
member may request to see/review any of the proposals
o List of grants with review assignments
o Evaluation forms
o Memo from Research Committee Chair with instructions and deadlines
• The Research Committee will be given two weeks to review the assigned grants and submit the
evaluations to PCCP Office.
Vol. 19 | Issue 03 | September 2018 44
D. Budgetary Allocations
• The budgetary requirements of the study proposal must be stated.
• A detailed allocation must be provided to support the total budget as proposed.
• The grants application must state the amount that it is seeking from the PCCP. A study of
national scope, may apply for a maximum of 300K. Research topics listed in the PCCP Research
agenda will be given priority.
• The approved amount will be at the discretion of the committee, with the Executive Board
granting final approval for disbursement.
• The total budgetary allocation will be released upon the approval of the Executive Board.
E. Grant Approval
• After a proposal is endorsed for funding, the Research Committee will submit their decision to the
Executive Board for approval.
• Upon approval, PCCP inform the council, through its respective Chair, of the Research
Committee’s decision. PCCP staff will also provide the proponents with the reviews and
comments to be answered by the proponents in two weeks.
• The letters should be mailed within a week of the Research Committee decision.
• The grant winner should be contacted to collect the information necessary for a check request, in
order to receive the grant money.
• A document from PCCP to be signed by the Principal Investigator and the Chair of the Research
Committee should outline the terms of the grant including target completion and progress report.
• Fifty percent of the approved budget should be released upon approval.
• An interim report within a year of approval must be made.
• The grant recipient will also be recognized at the PCCP Annual Convention Research
Presentation.
• The research results should be presented within a maximum of two years from funding.
• If the paper is mainly funded by PCCP then it reserves the right to publish the paper in its own
journal, unless it waives its rights.
• Works in progress must submit a progress report midway through the project, further tranches
maybe released based on the report
• Finished papers should be presented during the annual PCCP convention
• An acknowledgement of the PCCP support provided is expected with the publication of the study,
regardless of the amount of support, as part of disclosure and in recognition of the assistance.
Philipp J Chest Dis 201845
F. Grant Extension
• Grant recipients, upon written request to the Chair of the Research Committee, shall be granted
an extension beyond the anticipated completion of the research of a maximum of one year
• If, after the extension expires, the research project is still not completed, any further extension of
time shall be decided by the PCCP Executive Board and the Chair of the Research Committee.
• A paper not finishing during the proscribed period of implementation must justify in writing or else
forfeit the remainder of the funding and will be required to remit or reimburse the original funds
extended by PCCP.
G. Competition Eligibility
• PCCP funded research projects for individuals are not eligible for competition in PCCP
conventions.
II. GUIDELINES FOR APPROVAL OF RESEARCH GRANTS INDIVIDUAL/INSTITUTION
A. Research protocols should be submitted to the PCCP Research Screening Committee through
PCCP secretariat.
B. Protocols must contain the endorsement of the Section Chief of the Accredited Training Institution
and the Training Officer or Research Coordinator. Protocols must be submitted for review toy the
Institutional Review Board (IRB) and Ethics Committee.
C. Approved research protocols by the PCCP Research Committee should be submitted to the PCCP
Board of Directors for approval.
D. A document from PCCP to be signed by the Principal Investigator and the Chair of the Research
Committee should outline the terms of the grant including target completion and progress report.
The individual/institution may apply for a maximum of 50,000 Php. The budgetary allocation
however may be increased to 300,000 Php for a study of national scope.
E. Fifty percent of the approved budget should be released upon approval.
F. A completed report of the research should be submitted to the research committee and a progress
report in the middle of the project (according to its timeline).
G. If the paper is mainly funded by PCCP then it reserves the right to publish the paper in its own
journal, unless it waives its rights.
H. A progress report must be submitted midway through the project, further tranches maybe released
based on the report. The first 50% of the fund will only be released upon submission of the letter of
approval for the protocol by the institution’s Ethics Review Board or Ethics Committee. The grant
recipients are then required to submit a progress and a financial report every 3 months thereafter.
The next 40% of the fund will be given when they submit a report of their findings after 6 months,
indicating in the Gantt chart what have been achieved, as well as a financial report of their
expenses. 10% of the fund will be given when they present the completed data and analysis with
financial report.
Vol. 19 | Issue 03 | September 2018 46
J. Finished papers should be presented during the annual PCCP convention.
K. If the major source of the funding for the research project comes from PCCP research funds, then
PCCP unless it waives its rights, has the right to publish it in its own journal.
L. Any study that has received a grant from the PCCP must include the logo of the PCCP in oral or
spoken presentations. For publications, an acknowledgment is required.
M. A paper not finishing during the proscribed period of implementation must justify in writing or else
forfeit the remainder of the funding and required to remit or reimburse the original funds extended by
PCCP.
N. Research papers conducted in multiple sites are encouraged and allowed. However, for PCCP
funding purposes, a single coordinating institution and proponent will be principally responsible to
PCCP.
O. Completed report of research should be submitted to the PCCP according to the protocol timeline.
P. Finished papers should be presented during the PCCP annual convention but not included in the
research contest.
III. GUIDELINES FOR APPROVAL OF TRAVEL RESEARCH GRANTS FOR FELLOWS-IN-TRAINING
A. For pulmonary fellows-in-training, a yearly total allotment of 7,000 USD will be given for papers
accepted for international presentation (oral, poster) in amounts of 700 USD for oral presentations
and 500 USD for poster presentation each to be screened by the research committee and
approved by the PCCP board.
B. Criteria for inclusion are international conferences on pulmonary diseases and disorders and
excludes support for conferences conducted in the Philippines.
C. A maximum of three (3) grants per institution per year will be given.
D. Requirements: Application letter of fellow-in-training, endorsed by TO or head and acceptance
letter from the international scientific organization.
Philipp J Chest Dis 201847
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OUTSIDE BACK COVER
The Philippine Journal of Chest Diseases
An official publication of:
Philippine College of Chest Physicians
84-A Malakas St., Pinyahan, Quezon City, Philippines
Email: [email protected]
Phone: (+632) 924 9204