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11/20/2015 1 Eighth Bi-Annual Pediatric Sleep Medicine Conference November 12-15, 2015 Omni Amelia Island Plantation Resort Amelia Island, Florida Sponsored by The Warren Alpert Medical School of Brown University Carol L. Rosen, MD Case Western Reserve University School of Medicine Rainbow Babies & Children’s Hospital Cleveland, OH No relevant financial conflicts of interest to this presentation For respiratory-related PSG findings Practice pattern recognition skills Recognize commonly encounters artifacts Audience participation Have fun A. Central apnea B. Mixed apnea C. Obstructive apnea D. Obstructive hypopnea 120 sec

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11/20/2015

1

Eighth Bi-Annual Pediatric Sleep Medicine Conference

November 12-15, 2015Omni Amelia Island Plantation Resort

Amelia Island, Florida

Sponsored byThe Warren Alpert Medical School

of Brown University

Carol L. Rosen, MD

Case Western Reserve University School of Medicine

Rainbow Babies & Children’s Hospital

Cleveland, OH

No relevant financial conflicts of interest to this presentation

For respiratory-related PSG findings◦ Practice pattern recognition skills

◦ Recognize commonly encounters artifacts

Audience participation

Have fun

A. Central apneaB. Mixed apneaC. Obstructive apneaD. Obstructive hypopnea

120 sec

11/20/2015

2

A. Central apneaB. Mixed apneaC. Obstructive apneaD. Obstructive hypopnea

120 sec 120 sec in REMA. Central apneaB. Central hypopneaC. Obstructive apneaD. Obstructive hypopnea

120 sec in REMA. Central apneaB. Central hypopneaC. Obstructive apnea -uberD. Obstructive hypopnea Bonus Q, another event?

Hypopnea

41 Seconds

Inspiratory Breath Hold

Tachypnea

A. AchondroplasiaB. Congenital central hypoventilation C. Prader-WilliD. Rett’s

41 Seconds

Inspiratory Breath Hold

Tachypnea

A. AchondroplasiaB. Congenital central hypoventilation C. Prader-WilliD. Rett’s

Marcus CL et al. Polysomnographic characteristics of patients J Pediatr 1994;125:218-24.

EtCO2 values ~ 42 mmHgSpO2 average 97% with episodic desaturations

A. Central hypoventilationB. Central sleep apneaC. Heart failureD. Obstructive sleep apnea

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EtCO2 values ~ 42 mmHgSpO2 average 97% with episodic desaturations

A. Central hypoventilationB. Central sleep apneaC. Heart failureD. Obstructive sleep apnea

A. BruxismB. Load compensationC. Palatal myoclonusD. Snoring

N3 , 30 sec

A. BruxismB. Load compensationC. Palatal myoclonusD. Snoring

N3 , 30 sec120 secSpO2 averages 94%

EtCO2 average 35 mmHg

120 sec

#1 flow limitation

#2 tachypnea; >50 breaths/min

#3 SpO2 94%

Bonus question: is EtCO2 reliable? why or why not?

Not: likely underestimates because of tachypnea

A. OxygenB. PHOX2BC. Pulmonary referralD. Reassurance

120 sec in N3 sleepSpO2 mean 97%EtCO2 mean 35 mmHg

TcCO2 mean 41 mmHg

= 35 breaths/min

11/20/2015

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A. OxygenB. PHOX2BC. Pulmonary referralD. Reassurance

Tachypnea (-35/hr) with normal gas exchange

120 sec in N3 sleepSpO2 mean 97%EtCO2 mean 35 mmHgTcCO2 mean 41 mmHg = 35 breaths/min

120 sec120 sec

120 sec

A. Flow limitationB. HyperventilationC. Obstructive hypoventilationD. Technical problem

120 sec in N2 sleepSpO2 85- 97%EtCO2 mean 25 mmHg

A. Flow limitationB. HyperventilationC. Obstructive hypoventilationD. Technical problem

120 sec in N2 sleepSpO2 85- 97%EtCO2 mean 25 mmHg

No Pleth WaveformBad Pleth: SpO2 85-97%

Good Pleth: SpO2 98%

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120 sec in N3 sleepSpO2 mean 96%EtCO2 mean 54 mmHg

A. Normal breathingB. Obstructive hypoventilationC. Central hypoventilationD. Sleep-related hypoxemia

120 sec in N3 sleepSpO2 mean 96%EtCO2 mean 54 mmHg

A. Normal breathingB. Obstructive hypoventilationC. Central hypoventilationD. Sleep-related hypoxemia

EtCO2 wave

EtCO2 # 39 mmHg

Airflow

Chest effort

Abd effort

SpO2 100%90%

41 mmHg40 mmHg

Desat to 84%

36 mmHg38 mmHg

10 sec

Snore/noise

60 sec fragmentA. Cardiac evaluation

B. CNS imaging

C. CPAP titration

D. PHOX2B testing

EtCO2 wave

EtCO2 # 39 mmHg

Airflow

Chest effort

Abd effort

SpO2 100%90%

41 mmHg40 mmHg

Desat to 84%

36 mmHg38 mmHg

10 sec

Snore/noise

60 sec fragmentA. Cardiac evaluation

B. CNS imaging

C. CPAP titration

D. PHOX2B testing

A. AnemiaB. Abnormal hemoglobinC. Hydroxyurea therapyD. Obstructive sleep apnea

120 sec in N3 sleepSpO2 mean 84%EtCO2 mean 38 mmHg

A. AnemiaB. Abnormal hemoglobinC. Hydroxyurea therapyD. Obstructive sleep apnea

120 sec in N3 sleepSpO2 mean 84%EtCO2 mean 38 mmHg

11/20/2015

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A. Cheyne-Stokes respirationB. Central sleep apneaC. Central sleep apnea with hypoventilationD. Obstructive sleep apnea

120 sec in sleepSpO2 mean 92%TcCO2 61 mmHg

A. Cheyne-Stokes respirationB. Central sleep apneaC. Central sleep apnea with hypoventilationD. Obstructive sleep apnea

120 sec in sleepSpO2 mean 92%TcCO2 61 mmHg

120 sec in wakeSpO2 mean 98%

EtCO2 4020 mmHg

A. Cardiogenic artifactB. Cell phone artifactC. Diaphragm flutterD. Panic attack

120 sec in wakeSpO2 mean 98%

EtCO2 4020 mmHg

A. Cardiogenic artifactB. Cell phone artifactC. Diaphragm flutterD. Panic attack

Thank [email protected]