poster 415 reduction of uti incidence and bacteriuria in sci patient using standardized 36mg pac...

1
Poster 415 Reduction of UTI Incidence and Bacteriuria in SCI Patient Using Standardized 36mg PAC Cranberry Extract Supplement. Matthew Sand, MD (Shepherd Center, Atlanta, GA, United States); Chrissy Warren, MS. Disclosures: M. Sand, No Disclosures: I Have No Relevant Financial Relationships to Disclose. Case Description: Adult female patient with spinal cord injury that utilizes clean intermittent catheterization (CIC). Patient had a history of recurrent UTIs. Patient was initially administered one 100mg capsule B.I.D. of nitrofurantoin for 7 days, along with a once daily dose of 36mg Proanthocyanidins (PAC) in the form of a standardized cranberry extract. Once the antibiotic therapy was concluded, the patient continued to take the once daily dose of 36mg Proanthocyanidins (PAC) for 6 months. Setting: Rehabilitation Hospital. Results or Clinical Course: At 3 months and 6 months, a urinalysis was performed. There was a signicant reduction in asymptomatic bacteriuria, as well as reduced incidence of acute urinary tract infections. Discussion: Recurrent urinary tract infections (UTIs) are a frus- trating problem that plagues SCI patients and poses a challenge to practitioners. This UTI management method provides a cost- effective approach to prevention of infection and reduction in antibiotic utilization thus reducing antibiotic resistance. Conclusions: Reduction of UTI incidence and bacteriuria levels among SCI patients who self-catheterize can be achieved using a standardized 36mg PAC cranberry extract supplement. Poster 416 Partial Preservation of Sacral Sensation and Lower Motor Neuron Function in a Patient with Rhizotomy of Sacral Nerve Roots: A Case Report. Jeffrey LaVallee, MD (University of Virginia, Charlottes- ville, VA, United States); Geoffrey Smith, MD. Disclosures: J. LaVallee, No Disclosures: I Have No Relevant Financial Relationships to Disclose. Case Description: A 64-year-old woman with a large sacro- coccygeal chordoma. Setting: Inpatient rehabilitation hospital. Results or Clinical Course: The patient initially presented with a one-year history of lower back pain. Imaging revealed a large (9.8 cm 3 cm 8 cm) inltrative sacral mass extending into the spinal canal, which was biopsied and diagnosed as a sacrococcygeal chordoma. She subsequently underwent surgical resection of the chordoma, which included partial sacrumectomy, decompressive L5-S3 laminectomy, and rhizotomy of the right S2 and bilateral S3-S5 nerve roots. Postoperative physical examination revealed at least partial preservation of sensation to light touch and pin prick in all of the sacral dermatomes with the exception of the right-sided S3-S4 dermatome. The bulbocavernosis and anocutaneous reexes were partially preserved and there was a weak volitional anal contraction present. Given the partial preservation of sacral reexes the patient was started on a bowel program consisting of daily suppository with manual disimpaction as needed. This program was continued throughout her inpatient rehabilitation course with moderate success at maintaining bowel continence and was continued post discharge. Discussion: The nding of partially preserved lower sacral sensation and reexes on physical examination is inconsistent with the operative report stating that the right S2 and bilateral S3-S5 nerve roots were sacriced. In theory, this patient should have presented with saddle anesthesia and areexic pelvic oor. However, this was not the case with this patient, and the bowel program was adjusted accordingly. Possible explanations include an aberrant neuroanatomical variation of the lumbosacral plexus with pathways above S2 innervating structures typically innervated by the lower sacral nerve roots. It is unclear if the chordoma, which is thought to arise from ectopic notochord remnants, is associated with this aberrant anatomy or if this is coincidental. Conclusions: Neuroanatomical variations of the lumbosacral plexus may cause unexpected clinical outcomes. Poster 417 An Unusual Case of Bilateral C5 Palsy After Cervical Fusion. Melissa Xenidis, DO (Marianjoy Rehabilitation Hospital, Wheaton, IL, United States); Dennis Keane, MD. Disclosures: M. Xenidis, No Disclosures: I Have No Relevant Financial Relationships to Disclose. Case Description: A 76-year-old man with a history of mechanical fall and resultant neck pain, but normal neurological examination, was found with severe cervical stenosis from C3-4 to C6-7 on cervical MRI investigation. He underwent C3-T1 lam- inectomy and fusion, in which immediately post-op he was noted to have 0/5 strength in the bilateral C5 myotomes (shoulder abduction and elbow exion) as well as diminished pin prick sensation in the bilateral C5 dermatomes. Re-imaging of the cervical spine showed only post-op ndings and no signs of spinal cord or nerve root impingement. Setting: Acute Inpatient Rehabilitation Hospital. Results or Clinical Course: Neurologic symptoms persisted through his 3 week acute inpatient rehabilitation stay and upon discharge he was modied independent for transfers and gait, while requiring minimal assistance for his ADLs. Discussion: Unilateral C5 palsy is not an uncommon compli- cation after cervical laminectomy and fusion surgeries with the rate reaching as high as 10.6%. Symptoms can include paralysis of the deltoid and/or bicep brachii, with possible sensory decits and/or intractable pain in the corresponding dermatome. Though no direct causality can be linked with incidences, there are some anatomical considerations hypothesized. The rootlet and root of C5 are shorter than in other segments and may be more prone to tethering during vertebral body shifting. C5 is usually the apex of cervical lordosis and the midpoint of de- compression, which could place greater shifting movement at this segment. While 70% of affected patients show complete recovery from paralysis within 7.9 months, 30% remain with residual motor paralysis. Conclusions: Physicians and patients need to be aware of the potential risk of C5 palsy after cervical fusion surgery. Affected patients need to have adequate therapies, education, appropriate adaptive equipment to maximize functional independence, and much encouragement as with time the majority of affected patients will have full recovery. PM&R Vol. 6, Iss. 9S, 2014 S331

Upload: chrissy

Post on 16-Feb-2017

214 views

Category:

Documents


2 download

TRANSCRIPT

Page 1: Poster 415 Reduction of UTI Incidence and Bacteriuria in SCI Patient Using Standardized 36mg PAC Cranberry Extract Supplement

PM&R Vol. 6, Iss. 9S, 2014 S331

Poster 415Reduction of UTI Incidence and Bacteriuria in SCIPatient Using Standardized 36mg PAC CranberryExtract Supplement.Matthew Sand, MD (Shepherd Center, Atlanta, GA,United States); Chrissy Warren, MS.

Disclosures: M. Sand, No Disclosures: I Have No RelevantFinancial Relationships to Disclose.Case Description: Adult female patient with spinal cord injurythat utilizes clean intermittent catheterization (CIC). Patient hada history of recurrent UTIs. Patient was initially administered one100mg capsule B.I.D. of nitrofurantoin for 7 days, along witha once daily dose of 36mg Proanthocyanidins (PAC) in the form ofa standardized cranberry extract. Once the antibiotic therapy wasconcluded, the patient continued to take the once daily dose of36mg Proanthocyanidins (PAC) for 6 months.Setting: Rehabilitation Hospital.Results or Clinical Course: At 3 months and 6 months,a urinalysis was performed. There was a significant reduction inasymptomatic bacteriuria, as well as reduced incidence of acuteurinary tract infections.Discussion: Recurrent urinary tract infections (UTIs) are a frus-trating problem that plagues SCI patients and poses a challenge topractitioners. This UTI management method provides a cost-effective approach to prevention of infection and reduction inantibiotic utilization thus reducing antibiotic resistance.Conclusions: Reduction of UTI incidence and bacteriuria levelsamong SCI patients who self-catheterize can be achieved usinga standardized 36mg PAC cranberry extract supplement.

Poster 416Partial Preservation of Sacral Sensation and LowerMotor Neuron Function in a Patient with Rhizotomy ofSacral Nerve Roots: A Case Report.Jeffrey LaVallee, MD (University of Virginia, Charlottes-ville, VA, United States); Geoffrey Smith, MD.

Disclosures: J. LaVallee, No Disclosures: I Have No RelevantFinancial Relationships to Disclose.Case Description: A 64-year-old woman with a large sacro-coccygeal chordoma.Setting: Inpatient rehabilitation hospital.Results or Clinical Course: The patient initially presentedwith a one-year history of lower back pain. Imaging revealed a large(9.8 cm � 3 cm � 8 cm) infiltrative sacral mass extending into thespinal canal, which was biopsied and diagnosed as a sacrococcygealchordoma. She subsequently underwent surgical resection of thechordoma, which included partial sacrumectomy, decompressiveL5-S3 laminectomy, and rhizotomy of the right S2 and bilateralS3-S5 nerve roots. Postoperative physical examination revealed atleast partial preservation of sensation to light touch and pin prick inall of the sacral dermatomes with the exception of the right-sidedS3-S4 dermatome. The bulbocavernosis and anocutaneous reflexeswere partially preserved and there was a weak volitional analcontraction present. Given the partial preservation of sacral reflexesthe patient was started on a bowel program consisting of dailysuppository with manual disimpaction as needed. This programwas continued throughout her inpatient rehabilitation course

with moderate success at maintaining bowel continence and wascontinued post discharge.Discussion: The finding of partially preserved lower sacralsensation and reflexes on physical examination is inconsistent withthe operative report stating that the right S2 and bilateral S3-S5nerve roots were sacrificed. In theory, this patient should havepresented with saddle anesthesia and areflexic pelvic floor.However, this was not the case with this patient, and the bowelprogram was adjusted accordingly. Possible explanations includean aberrant neuroanatomical variation of the lumbosacral plexuswith pathways above S2 innervating structures typically innervatedby the lower sacral nerve roots. It is unclear if the chordoma, whichis thought to arise from ectopic notochord remnants, is associatedwith this aberrant anatomy or if this is coincidental.Conclusions: Neuroanatomical variations of the lumbosacralplexus may cause unexpected clinical outcomes.

Poster 417An Unusual Case of Bilateral C5 Palsy After CervicalFusion.Melissa Xenidis, DO (Marianjoy Rehabilitation Hospital,Wheaton, IL, United States); Dennis Keane, MD.

Disclosures: M. Xenidis, No Disclosures: I Have No RelevantFinancial Relationships to Disclose.Case Description: A 76-year-old man with a history ofmechanical fall and resultant neck pain, but normal neurologicalexamination, was found with severe cervical stenosis from C3-4 toC6-7 on cervical MRI investigation. He underwent C3-T1 lam-inectomy and fusion, in which immediately post-op he was notedto have 0/5 strength in the bilateral C5 myotomes (shoulderabduction and elbow flexion) as well as diminished pin pricksensation in the bilateral C5 dermatomes. Re-imaging of the cervicalspine showed only post-op findings and no signs of spinal cord ornerve root impingement.Setting: Acute Inpatient Rehabilitation Hospital.Results or Clinical Course: Neurologic symptoms persistedthrough his 3 week acute inpatient rehabilitation stay and upondischarge he was modified independent for transfers and gait, whilerequiring minimal assistance for his ADLs.Discussion: Unilateral C5 palsy is not an uncommon compli-cation after cervical laminectomy and fusion surgeries with therate reaching as high as 10.6%. Symptoms can include paralysisof the deltoid and/or bicep brachii, with possible sensory deficitsand/or intractable pain in the corresponding dermatome.Though no direct causality can be linked with incidences, thereare some anatomical considerations hypothesized. The rootletand root of C5 are shorter than in other segments and may bemore prone to tethering during vertebral body shifting. C5 isusually the apex of cervical lordosis and the midpoint of de-compression, which could place greater shifting movementat this segment. While 70% of affected patients show completerecovery from paralysis within 7.9 months, 30% remain withresidual motor paralysis.Conclusions: Physicians and patients need to be aware of thepotential risk of C5 palsy after cervical fusion surgery. Affectedpatients need to have adequate therapies, education, appropriateadaptive equipment to maximize functional independence, andmuch encouragement as with time the majority of affected patientswill have full recovery.