positions that were not included in last month’s e-mail ... · eunice kennedy shriver . national...

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Thursday, January 6, 2011 1:58 PM Page 1 of 19 From: Owens, Roland (NIH/OD) [E] [[email protected]] Sent: Wednesday, January 05, 2011 3:25 PM Subject: NIH Research Positions-January Update Dear Colleagues: Please feel free to pass on these job advertisements as you see fit. The NIH Intramural Research Program provides an ideal environment for scientists, with competitive start up packages (for its tenure-track and tenure-eligible positions) and no grant writing or teaching requirements. The NIH is dedicated to building an inclusive and diverse community in its training and employment programs. Four positions that were not included in last month’s e-mail are labeled “Newly Advertised”. Sincerely, Roland A. Owens, Ph.D. Assistant Director, Office of Intramural Research Office of the Director National Institutes of Health U.S. Department of Health and Human Services E-mail: [email protected] Tenure-Track Position Laboratory of Neurogenetics, NIA (deadline: January 22) The Laboratory of Neurogenetics (LNG) of the National Institute on Aging (NIA) is recruiting an independent scientist for a Tenure Track position within its Intramural Research Program (IRP) in Bethesda, MD. This position is 100% research and provides the unique and extensive resources of the NIH. The successful candidate will have a strong background and extensive experience in the molecular genetics of neuromuscular diseases. Specialized knowledge and expertise in the genetics of simple, Mendelian disease as well as experience in defining the role of genetics in complex disease is required. In particular experience with genome wide methods to assess the role of

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Page 1: positions that were not included in last month’s e-mail ... · Eunice Kennedy Shriver . National Institute of Child Health and Human Development (NICHD), a major research component

Thursday, January 6, 2011 1:58 PM

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! From: Owens, Roland (NIH/OD) [E] [[email protected]] Sent: Wednesday, January 05, 2011 3:25 PM Subject: NIH Research Positions-January Update Dear Colleagues: Please feel free to pass on these job advertisements as you see fit. The NIH Intramural Research Program provides an ideal environment for scientists, with competitive start up packages (for its tenure-track and tenure-eligible positions) and no grant writing or teaching requirements. The NIH is dedicated to building an inclusive and diverse community in its training and employment programs. Four positions that were not included in last month’s e-mail are labeled “Newly Advertised”. Sincerely, Roland A. Owens, Ph.D. Assistant Director, Office of Intramural Research Office of the Director National Institutes of Health U.S. Department of Health and Human Services E-mail: [email protected] Tenure-Track Position Laboratory of Neurogenetics, NIA (deadline: January 22) The Laboratory of Neurogenetics (LNG) of the National Institute on Aging (NIA) is recruiting an independent scientist for a Tenure Track position within its Intramural Research Program (IRP) in Bethesda, MD. This position is 100% research and provides the unique and extensive resources of the NIH. The successful candidate will have a strong background and extensive experience in the molecular genetics of neuromuscular diseases. Specialized knowledge and expertise in the genetics of simple, Mendelian disease as well as experience in defining the role of genetics in complex disease is required. In particular experience with genome wide methods to assess the role of

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Job Openings at the National Institutes of Health January - 2011
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common and rare genetic variants in disease is highly desirable and specifically, experience in running and analyzing genome wide association studies and large-scale second generation sequencing experiments. The incumbent will direct the research goals and resources of the Neuromuscular Disease Research Unit, in addition to playing a role in the management structure of the LNG. The incumbent will play a major role in training staff and postdoctoral fellows and maintaining research continuity within the laboratory. An M.D., Ph.D., or equivalent degree is required. Salary is commensurate with research experience and accomplishments, and a full Civil service package of benefits (including retirement, health, life and long term care insurance, Thrift Savings Plan participation, etc.) is available. Additional information regarding the NIA, IRP and the LNG are available at the following website http://www.grc.nia.nih.gov. To apply: Please send cover letter, curriculum vitae, bibliography, statement of research interest and three letters of recommendation to: Peggy Grothe, Intramural Program Specialist; Office of the Scientific Director, Vacancy # NIA-IRP-11-02, National Institute on Aging, NIH Biomedical Research Center, 251 Bayview Blvd., Suite 100, Baltimore, Maryland 21224. Applications must be received by January 22, 2011. If additional information is needed, please call 410-558-8012 or e-mail to [email protected]. DHHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs.

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Senior Investigator and Head Humoral Immunology Section, VRC (deadline: February 1) The Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) is seeking an outstanding candidate to head the newly established Humoral Immunology Section, within the Virology Laboratory, located at Building 40, 40 Convent Drive, main NIH campus, Bethesda, Maryland. This new section will closely interact with the Virology Laboratory Section, the Structural Biology Section, the BSL-3 Virology Section, and the Structural BioInformatics Section, all located within the Virology Laboratory. All these laboratories support the VRC mission objectives of developing an HIV-1 vaccine candidate that elicits neutralizing antibodies to circulating viral isolates, and advancing such a vaccine into clinical trials. The Chief of the Humoral Immunology Section will exercise scientific leadership and be responsible for evaluating basic research vaccine strategies to elicit antibodies that neutralize HIV, and for studying antibody-mediated protective immune responses against HIV-1. Specifically, the Chief of the Humoral Immunology Section will be responsible for conducting independent intramural research on understanding antibody-mediated protective immune responses against HIV-1 via studies of both the plasma antibody compartment and the B-cell compartment. He/she will be responsible for conducting top-tier independent research to define structural and functional mechanisms of Env neutralization, and to evaluate antibody responses from natural disease infection and from preclinical and clinical vaccine studies. It is expected that research conducted by this Senior Investigator will serve as a critical basis for development of tangible products for prevention of HIV-1 infection. The incumbent will serve as a member of the VRC Principal Investigator group which

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advises the VRC Director regarding scientific progress, and future scientific directions including design, planning and execution of basic, translational and clinical research. The Chief of the Humoral Immunology Section will have independent resources to carry out the research activities described above, as appropriate. The qualified candidate will have an M.D., or Ph.D., and should be an acknowledged authority and expert in humoral immunology and HIV vaccine development. In addition the selected individual will have demonstrated proven ability to independently carry out a strong independent research program. The selected individual will also be expected to contribute to and provide oversight of collaborative basic, translational and clinical research, involving or based upon vaccine strategies intended to elicit antibodies that neutralize HIV, or to study antibody-mediated protective immune responses against HIV-1. Salary will be based on the individual’s qualifications and experience. To apply for the position, interested candidates should submit their curriculum vitae, bibliography, a detailed statement of how your expertise can contribute to the success of the mission goals of the Humoral Immunology Section along with three letters of reference to: National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Attn: Bryan McClelland Building 40, Room 1100; 40 Convent Drive; Bethesda, MD 20892-3013 or email to [email protected] by February 1, 2011. Interested candidates may contact Dr. Richard Koup, Chair, NIAID Search Committee, at [email protected] for further information. Further information regarding VRC laboratories is available at www.niaid.nih.gov/about/organization/vrc/Pages/default.aspx <http://www.niaid.nih.gov/about/organization/vrc/Pages/default.aspx> . DHHS and NIH are Equal Opportunity Employers.

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Newly Advertised Scientific Director Division of Intramural Research, NICHD (deadline: February 15) The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (HHS), seeks to identify an outstanding Scientific Director to lead its Division of Intramural Research (DIR), located in Bethesda, Maryland. The NICHD Scientific Director leads a basic and clinical research program directed toward developing a greater understanding of the biological, medical, reproductive and behavioral aspects of normal and abnormal human development. The NICHD’s current research emphasis is on the cellular and molecular developmental mechanisms and interactions that guide a single fertilized egg cell through its development into a multi-cellular, highly organized and specialized adult organism. This position offers a unique and exciting opportunity for an extremely capable individual to develop and implement an overall vision for the NICHD/DIR and to plan and oversee basic fundamental, clinical and applied research programs. The Scientific Director will evaluate research efforts and establish program priorities, allocate resources, direct training of pre-doctoral and post-doctoral fellows, collaborate with other NIH programs, and advise the NICHD Director and senior staff on DIR programs and on areas of scientific interest to the Institute. The incumbent plays a key role in

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creating and maintaining a nurturing research environment that encourages creativity, collaboration among scientists from different disciplines, effective training of post-doctoral fellows, and efficient utilization of resources. The DIR has a staff of approximately 1,200 and a current annual budget in excess of $185 million. In addition to the managerial/administrative responsibilities outlined above, the Scientific Director is expected to carry out his/her own high quality research program. Resources commensurate with the proposed program will be provided. QUALIFICATIONS: Applicants must possess an M.D., Ph.D., or equivalent degree, and have demonstrated scientific leadership and/or senior-level research experience in a basic and/or clinical research program of national and international standing in an area relevant to maternal and child health or human development. The successful candidate will have a compelling vision for the future of the field, proven experience in managing and directing a scientific research program, and well-honed administrative and interpersonal skills. The NICHD seeks candidates who have a commitment to scientific excellence and the energy, enthusiasm, and innovative thinking necessary to maintain the DIR’s research efforts at the forefront of science. SALARY/BENEFITS: Salary is competitive and will be commensurate with the experience of the candidate. A full package of Federal Civil Service benefits is available, including: retirement, health and life insurance, long term care insurance, leave, and a Thrift Savings Plan (401K equivalent). The successful candidate is subject to a background investigation and financial disclosure requirements. HOW TO APPLY: Interested candidates should submit a letter of interest, including a brief description of research and administrative experience; curriculum vitae and bibliography; and full contact information of five references. Application packages should be sent via e-mail to Mr. Michael Rosenthal at: [email protected]. Applications should be received by February 15, 2011. HHS and NIH are Equal Opportunity Employers

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Newly Advertised Senior Investigator Division of Intramural Research, NIDA (deadline: February 25) The Intramural Research Program (IRP), National Institute of Drug Abuse (NIDA), a research component of the National Institutes of Health (NIH), Department of Health and Human Services (DHHS), is seeking an outstanding and internationally recognized senior scientist to initiate a multidisciplinary cognitive neuroscience program aimed at determining the behavioral, cognitive, and physiological mechanisms of substance use, abuse and addiction. The successful candidate must possess a Ph.D., M.D., or D.O. degree and have an outstanding publication record in cognitive neuroscience and substance abuse. In view of the required integrative approach, the successful candidate will be expected to collaborate with other research groups within NIDA and NIH - a proven ability to establish and sustain collaborative work is highly desirable. Candidates must submit a CV, a statement of proposed research objectives and goals (3 pages or less), 4 letters of recommendation (from non-collaborators) to: Joshua Kysiak, Intramural Program Specialist, NIDA IRP, 251 Bayview Boulevard, Suite 200, Room 04A524, Baltimore, Maryland 21224. Telephone 443-740-2465, FAX

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443-740-2865, Email: [email protected]. Application materials must be received by close of business on February 25, 2011; late applications will not be considered. DHHS and NIH are Equal Opportunity Employers.

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Newly Advertised Scientific Director Division of Intramural Research, NIEHS (deadline: February 28) The National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health is seeking exceptional candidates for the position of Scientific Director for its Division of Intramural Research (DIR). The Scientific Director sets the priorities of the intramural research program and advises the Director on the scientific direction of the NIEHS. The NIEHS supports and conducts research to understand biological and chemical processes and the contribution of environmental agents to human disease and dysfunction, including mechanisms of environmentally associated diseases (www.niehs.nih.gov <http://www.niehs.nih.gov> ). Areas of research include but are not limited to Molecular Pharmacology and Toxicology, Molecular Genetics, Structural Biology, Signal Transduction, Neurobiology, Molecular Carcinogenesis, Reproductive and Developmental Toxicology, Comparative Medicine, Epidemiology, Respiratory Biology, Biostatistics and Clinical Research. This position offers a unique and exciting opportunity for an extremely capable leader to plan and oversee basic and applied research programs, evaluate research efforts, establish program priorities, allocate resources, direct training of pre-and post-doctoral fellows, collaborate with other NIH programs, foster interdisciplinary synergistic biomedical research, and advise the NIEHS Director and senior staff on the DIR and areas of science of interest to the Institute. The DIR is organized into four scientific programs including 12 laboratories and branches conducting laboratory, clinical, and population-based research. The Intramural Division has a staff of approximately 800 employees with an annual budget of approximately $110M. The selected candidate may have a modest independent research program if funds and space are available. The NIEHS seeks candidates who have a commitment to scientific excellence and the energy, enthusiasm, and innovative thinking necessary to lead a dynamic and diverse research program. Applicants must have a MD, PhD or equivalent degree and should have demonstrated scientific leadership and extensive scientific accomplishments including a research program of national and international standing in an area relevant to environmental health. Salary is commensurate with level of experience and accomplishments. Interested candidates should send a cover letter including a brief description of research and administrative experience, a one-page vision statement for leading the DIR, curriculum vitae with bibliography, and full contact information for three to five individuals who may be contacted to provide letters of reference to: Ms. Stephanie Jones (DIR-11-01), Office of Human Resources, NIH, PO Box 12233,(MD K1-01), Research Triangle Park, NC 27709; or via email to [email protected] by February 28, 2011. DHHS and NIH are Equal Opportunity Employers. We are dedicated to building a diverse community in our training and employment programs.

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Newly Advertised Statistician, Tenure or Tenure-Track Radiation Epidemiology Branch, DCEG-NCI (deadline: April 15) The Radiation Epidemiology Branch (REB, http://dceg.cancer.gov/reb, Chief, Dr. Martha Linet), a component of NCI’s intramural Division of Cancer Epidemiology and Genetics (DCEG), is recruiting a statistician to develop an independent research program focusing on development of statistical models that incorporate dose uncertainties, that provide cancer risk projections for low-dose exposures, that can be used to estimate radiation-induced lifetime risks, that quantify the effect of key modifiers on radiation-related cancer risks, or that provide mathematical formulations of biological models for radiation carcinogenesis. Current REB research includes studies of late effects of radiological diagnostic examinations, radiotherapy, occupational exposures, or nuclear fallout from above-ground tests, military sources (Japanese atomic bomb survivors) or radiation accidents (Chernobyl). REB is also evaluating late health effects of new radiation technologies in medicine including the estimation of doses, extremely low-frequency and radio-frequency electromagnetic field exposures, and ultraviolet radiation. In addition, REB studies are examining gene-radiation interaction in studies of breast and thyroid cancer, etiologic and genetic studies (including genome-wide association studies) of brain tumors and thyroid cancer, and the development of various strategies for reconstructing historical radiation doses of medical radiation workers and populations exposed to environmental, military, and accidental sources of radiation exposure. Challenges for the statistician include modeling the excess relative and absolute risk as a function of dose, evaluating the modifying effects of dose-rate and type of radiation, addressing effects on risk estimates of uncertainties from complex dosimetry systems, developing appropriate analytic approaches for special study designs, identifying and describing gene-environment interaction, and developing strategies to identify true associations in genome-wide scans for disease-producing genetic variants. REB investigators are encouraged to collaborate with scientists in other parts of the DCEG, including members of the Biostatistics Branch and the Human Genetics Program. Candidates must have a doctorate in biostatistics, statistics, mathematics or a related discipline (with additional post-doctoral experience in statistics). They must have at least two years of post-doctoral research experience and an established record of publications that demonstrates their ability to apply cutting edge, appropriate statistical models and analyze and interpret data from radiation epidemiology studies. They should also have knowledge of and demonstrated capacity to apply state-of-the-art statistical and epidemiologic methods in at least one of the following areas of research: risk assessment, measurement (dosimetry) errors, genetic susceptibility in relation to radiation carcinogenesis, or mechanisms of radiation carcinogenesis. Collaboration with epidemiologists, dosimetrists, health or medical physicists, radiologists, and laboratory investigators is central to the success of our research. Candidates must document the strong verbal and written communication skills that will be required to write effective research papers, present work at scientific meetings, and convey information clearly to staff, collaborators, consultants and contractors. Candidates must also be sufficiently experienced to function independently, both in the development of their own research efforts and in the mentoring and supervision of less experienced investigators. Appropriate office space and resources will be provided.

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Salary is competitive and commensurate with research experience and accomplishments, and a full Civil Service package of benefits (including retirement, health insurance, life insurance, and a thrift savings plan) is available. Candidates may be eligible for the NIH Loan Repayment Program (http://www.LRP.NIH.gov). This position is not restricted to U.S. citizens. Interested individuals should send a cover letter, curriculum vitae, brief summary of research interests, experience and future plans, copies of no more than 5 selected publications and three letters of reference to: Ms. Judy Schwadron; Division of Cancer Epidemiology and Genetics; National Cancer Institute; 6120 Executive Blvd., Room EPS 8073; Rockville, MD 20852-7242; or e-mail: [email protected]. The closing date of the advertisement is April 15, 2011. A completed package of your application is required in order to be considered for this position. DHHS and NIH are Equal Opportunity Employers.

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Staff Scientist Neuro-Oncology Branch, NCI (deadline: open-ended) The Neuro-Oncology Branch, a trans-Institute program of the National Cancer Institute and the National Institute of Neurological Disorders and Stroke of the National Institutes of Health, is recruiting a Staff Scientist to work in the area of stem cell and/or cancer stem cell genomics and biology. Laboratory projects include the molecular and genetic study of primary glial neoplasms and neural and glioma stem cells for the purpose of identifying stem cell associated signal transduction mechanisms responsible for stem cell self renewal, proliferation, and differentiation. The successful candidate should have a M.D. or Ph.D. degree and at least 3 years of post-doctoral training in molecular and cellular biology. Experience in cancer and/or stem cell biology would be desirable. Please send curriculum vitae, statement of research interests, and two letters of reference to: Howard A. Fine; Chief Neuro-Oncology Branch, National Cancer Institute; 9030 Old Georgetown Rd., Rm. 225; Bethesda, MD 20892; or [email protected]. Candidates may be U.S. citizens, resident aliens, or nonresident aliens. DHHS, NIH, the National Cancer Institute, and the National Institute of Neurological Disorders and Stroke are Equal Employment Opportunity and Affirmative Action employers that value and foster diversity throughout the entire organization.

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Staff Clinician CC and NHGRI Office of Rare Diseases (deadline: open-ended) The NIH is seeking a general internist for a joint appointment in the Internal Medicine Consult Service (IMCS) of the Clinical Center (CC) and the Undiagnosed Diseases Program (UDP), Office of Rare Diseases, National Human Genome Research Institute and the Clinical Center. The Internal Medicine Consult Service provides advice and management for adult patients admitted to specialty

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services at the NIH Clinical Center. The Undiagnosed Diseases Program (UDP) is a trans-NIH initiative whose goals are to provide answers to patients with mysterious conditions that have long eluded diagnosis and to advance medical knowledge about rare and common diseases. As a physician for this rogram, the internist will have the opportunity to capitalize on resources at the nation’s largest hospital devoted entirely to research. As part of this joint program, the internist will consult with patients presenting symptoms of unknown disorders. The overall purpose of the consultations is to determine a diagnosis and/or a possible therapeutic intervention. The internist will be a key member of a collaborative team, which includes several senior attending physicians who participate in the program’s clinical research. The candidate must have an M.D. or M.D/Ph.D. degree and be board certified in internal medicine or family practice, with considerable experience. Clinical expertise in the care of patients with genetic disorders and a strong interest in research are preferred. Curriculum vitae, bibliography, three letters of reference, and selected publications should be submitted to Dr. Fred Gill at: 10 Center Drive, Building 10 (CRC), 2-2731, MSC 1517, Bethesda, MD 20892. Phone: 301 496 9397, e-mail [email protected]. Salary is based on relevant experience and education. DHHS and NIH are Equal Opportunity Employers and encourage applications from women and minorities.

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Tenure Track Position Office of the Scientific Director, NEI (deadline: open-ended) The National Eye Institute (NEI), Office of the Scientific Director, seeks an outstanding clinician-scientist for a tenure-track position to develop an independent translational research program with focus on retinal diseases. The candidate will examine and treat patients with ophthalmic disease, and conduct clinical trials. NEI has particular interest in clinical research related to neuronal-glial interactions in retinal diseases and to genetic retinal degenerative diseases. The candidate must hold an M.D. or M.D./Ph.D. degree from a school in the US or Canada, or an equivalent degree from a foreign medical school. Candidates must be Board-certified by the American Board of Ophthalmology or Board-eligible and are expected to have completed post-residency fellowship training in Medical or Surgical Retina. Salary is commensurate with research experience and accomplishments. A full Federal package of benefits is available (including retirement, health, life and long term care insurance, Thrift Savings Plan etc). This position will remain open until filled. Interested applicants should submit an electronic application including curriculum vitae, a detailed statement of the proposed research, copies of their five most significant publications, and three reference letters to Ms. Mica Gordon at [email protected]. The National Eye Institute does not discriminate in employment on the basis of race, color, religion, sex, national origin, political affiliation, sexual orientation, marital status, disability, age, membership in an employee organization, or other non-merit factor. DHHS and NIH are Equal Opportunity Employers. NIH is dedicated to building a diverse community in its training and employment. NIH is a part of the U.S. Department of Health and Human Services.

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Research Scientist Laboratory of Sensorimotor Research, NEI (deadline: open-ended) The intramural program of the National Eye Institute invites applications for a position as a research scientist within the Laboratory of Sensorimotor Research. This position may be either tenured, or tenure track with conversion to tenure anytime within six years. Applicants will be expected to establish an independent research program related to understanding the neurobiology of the visual and/or oculomotor system. The Laboratory of Sensorimotor Research is devoted to understanding the organization of the brain related to the control of eye movements and visual perception. It has excellent facilities for the study of these systems in awake behaving primates, including dedicated computer systems, a machine shop, an electronics shop, and a histology lab. The Laboratory also provides the opportunity to collaborate on studies of human patients with diseases related to the visual and oculomotor systems. Although the Laboratory of Sensorimotor Research has historically studied primates, scientists using other species to study systems-level organization in ways not currently possible in primates will also be considered. Applicants should have a PhD or an MD/PhD and an outstanding record of accomplishments in visual or visuomotor systems neuroscience. This position will remain open until filled. Candidates should send a brief cover letter, curriculum vitae, bibliography, a one- or two-page statement of current research interests, copies of five recent, relevant publications, and three letters of recommendation to Okihide Hikosaka, Search Committee Chair, Building 49, Room 2A50, NIH, Bethesda, MD 20892-4435. DHHS and NIH are Equal Opportunity Employers.

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Systems Biology/Bioinformatics Staff Scientist Neuro-Oncology Branch, NCI-NINDS (deadline: open-ended) The Neuro-Oncology Branch, a trans-institute program of the National Cancer Institute and the National Institute of Neurological Disorders and Stroke of the National Institutes of Health is seeking an outstanding candidate to work in the area of cancer genomics, bioinformatics and systems biology, particularly on computational modeling of signaling and gene networks in cancer cells. Ongoing projects include the integration of -omics and clinical data in the exploration of signaling and transcriptional networks that govern cell differentiation, proliferation and migration in primary brain tumors, cancer tumor stem cells and normal embryonic neural stem cells and the translation of those discoveries to patients through the highly integrated clinical brain tumor research program. Applicants should have a strong background in mathematical and computational modeling and be expected to carry out an interdisciplinary project with experimental groups. The Staff Scientist candidate will take a lead role in the mentorship and scientific management of a team of bioinformatics research fellows. The following skills and qualifications are required: 1) PhD in computer science, mathematics, bioinformatics, or related fields, and at least 3 years of post-doctoral

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training in bioinformatics and/or systems biology; 2) experience in machine learning and network generation algorithms; 3) basic knowledge of cell/molecular biology; 4) experience in genome-wide genetic and gene expression data analysis. Please send curriculum vitae, statement of research interests and two letters of reference to: Howard A. Fine, Chief; Neuro-Oncology Branch, National Cancer Institute; MSC 8200, Room 225; 9030 Old Georgetown Road; Bethesda, MD 20892-8200 or to [email protected]. Candidates may be U.S. citizens, resident aliens, or nonresident aliens. DHHS, NIH, the National Cancer Institute and the National Institute of Neurological Disorders and Stroke are Equal Employment Opportunity and Affirmative Action employers that value and foster diversity throughout the entire organization.

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Chief Laboratory of Computational Medicine, NEI (deadline: open-ended) The NEI seeks to develop a new program in computational analysis that fully employs human genomic, transcriptomic, proteomic, metabolomic, neurophysiological and clinical data sets to reconstruct biological networks characteristic of normal and disease states. The magnitude, diversity, rich information content, and hierarchical connectivity of these data sets require the utilization and development of novel quantitative tools. The goal is to understand human disease at a molecular level in order to develop mechanism-based therapeutic interventions. We invite applications for head of a new laboratory of Computational Medicine within the NEI Intramural Research Program. This initiative seeks to integrate and translate knowledge from genetics and biology to a wide range of disease processes using systems, network, statistical and bioinformatics approaches. * Examples in ocular biology amenable to a systems approach would include neuro-immune interactions, gene regulatory networks during disease pathogenesis, protein interaction pathways, neuron-glial-vascular biological networks in the retina, neuronal networks in the CNS, and developmental conditions and disorders. * The research program has interest in developing novel computational methodologies for analyzing large genetic, biological, biomedical, neuronal, and functional data sets. Particular attention will be paid to genotype-phenotype correlations, gene-gene and gene-environment interactions. In parallel, we will actively seek to develop disease intermediate phenotypes that reflect the underlying biology and pathophysiology of disease. * Data sets from large clinical trials, genetic studies (including GWAS), expression profiling in normal and disease conditions, and from the eyeGENE human research repository for monogenic ophthalmic diseases will be developed to reconstruct and understand ocular biological networks that link genetic perturbations, small molecule interactions, and physiological processes, to predict normal and disease states

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The NEI/NIH provides an exceptional environment of dedicated scientists as well as a wide range of resources. We currently envision that this program will be located in the newly constructed Porter Neuroscience complex that houses a diverse set of investigators from many different Institutes. The successful candidate will be expected to recruit tenure-track faculty in areas that may include computational medicine or neuroscience, network biology, genetic or molecular epidemiology, cell and molecular biology, statistical genetics, bioinformatics, and biostatistics into the new Laboratory of Computational Medicine. Applicants should have a MD, MD/PhD or PhD and an outstanding record of accomplishments in genetics, epidemiology, neuroscience, cell and molecular biology, biostatistics, or a related quantitative discipline. Senior scientists would have the opportunity to maintain their participation in existing collaborative research in non-eye diseases if desired. This position will remain open until filled. Applicants should submit curriculum vitae, bibliography, copies of their five most significant publications, a summary of research accomplishments, names of three references, and a detailed experimental plan for the development of this program. These materials should be sent to: The Office of the Scientific Director, National Eye Institute, Attention: Ms. Mica Gordon ([email protected]), NIH Building 31, 31 Center Drive, Room 6A22, Bethesda, MD, 20892. The National Eye Institute does not discriminate in employment on the basis of race, color, religion, sex, national origin, political affiliation, sexual orientation, marital status, disability, age, membership in an employee organization, or other non-merit factor. DHHS and NIH are Equal Opportunity Employers.

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Chief, Visuomotor Disorders Section Laboratory of Sensorimotor Research, NEI (deadline: open-ended) The National Eye Institute (NEI) seeks an outstanding clinician scientist for a tenured or tenure-track position as Chief, Visuomotor Disorders Section in the Laboratory of Sensorimotor Research (LSR) in the Division of Intramural Research. This recruitment is directed towards clinicians with expertise in central disorders that affect vision and/or eye movements (including disorders of binocular function). The post offers a unique opportunity for a talented individual to provide strong and stimulating leadership in an organization dedicated to uncovering new scientific knowledge, both laboratory and clinical. We welcome the full range of candidates at all levels. The Laboratory of Sensorimotor Research is devoted to understanding the organization of the brain related to the control of eye movements, visual perception and their disorders. The Visuomotor Disorders Section Chief is expected to create a vigorous research program dedicated to elucidating the role played by these brain mechanisms in human disease, and to explore treatments. The Chief will develop broad investigational plans, independently and in collaboration with other NEI investigators and research scientists in the United States and abroad. The Chief will examine and treat patients, as well as design, implement and conduct research and clinical protocols. An opportunity exists for the Section Chief to recruit staff and supervise training. The NEI provides an exceptional environment for clinical research including the infrastructure necessary for patient recruitment, a clinical protocol development group, and a Contract Research Organization that provides statistical and epidemiological expertise, data management and analysis, study monitoring,

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regulatory guidance, and overall operational support. The NIH Clinical Center provides additional access to exceptionally broad medical and diagnostic resources. In addition, the LSR provides exceptional support for more specialized needs, such as the measurement of eye movements and computational analysis/modeling. The position requires an ability to integrate basic, clinical and translational research, and create an intellectual synergy and an environment for state-of-the art patient care for those suffering from visual dysfunction. At a minimum, candidates should have a Doctor of Medicine degree from a school in the U.S. or Canada approved by a recognized accrediting body in the year of the applicant's graduation, or a Doctor of Medicine or equivalent degree from a foreign medical school which provided education and medical knowledge substantially equivalent to accredited schools in the United States. Candidates should be Board-certified, board eligible or equivalent, have direct clinical experience. Salary is commensurate with research experience and accomplishments. A full Federal package of benefits is available (including retirement, health, life and long term care insurance, Thrift Savings Plan etc). Applicants should submit curriculum vitae, bibliography, copies of their five most significant publications, a summary of research accomplishments and three reference letters. Applicants should also submit a written statement with their perspective on the needs and opportunities necessary to move from the basic understanding of brain mechanisms supporting vision and eye movements to clinical therapeutic interventions and improved patient care. This statement should indicate how the applicant's particular expertise and background could contribute to this transition. Applications should be sent to: Mica Gordon, Executive Assistant, Office of the Scientific Director, National Eye Institute, Building 31, Room 6A22, 31 Center Drive, Bethesda, MD 20892; Tel: 301-451-6763, Email: [email protected]. NIH is dedicated to building a diverse community in its training and employment. NIH is a part of the U.S. Department of Health and Human Services.

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An asterisk next to the closing date in the postings above indicates that applications will continue to be accepted and considered until the position is filled. Below are such positions that still might be accepting applications, listed by the most recent. (That is, no one has told me to remove this posting; check with the contact person listed before applying.)

Tenure Track or Tenure-Eligible Investigator Biostatistics and Bioinformatics Branch, NICHD The Division of Epidemiology, Statistics and Prevention Research (DESPR) of the Eunice Kennedy

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Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), invites applications for the position of Tenure Track or Tenure-Eligible Investigator in the Biostatistics & Bioinformatics Branch (BBB). BBB investigators develop statistical research programs and actively collaborate in cutting-edge studies of genetics, lifestyle, and other environmental causes of reproductive, perinatal and adolescent outcomes. Statistical research is typically motivated by analytic issues encountered in Division studies, including modeling complex longitudinal data, modeling recurrent events, developing new approaches for assessing risk, developing strategies to identify true associations in genome-wide scans for disease-producing genetic variants, and the analysis of nutritional data. Increasingly, analytic issues involving digital imaging and “omics” data are becoming important in Division projects. For example, many Division projects have research components focusing on examining biological function as measured by proteomics, metabolomics, along with other high dimensional biomarkers. These measurements are often longitudinal, raising exciting research opportunities in study design and analysis. Given the Branch's current mix of expertise, we are particularly interested in candidates with established experience in bioinformatics, the analysis of high-dimensional data, and statistical genetics methodology. Applications will be evaluated on demonstrated potential to develop a creative, independent program of statistical research. Available resources include state of the art computing facilities (e.g., the NIH Biowulf cluster super computer), programming support for statistical methodology and collaborative projects from on-site computer and statistical contractors, and access to a diverse array of databases that have longitudinal and high-dimensional data for statistical methods development. Candidates must have an earned doctorate in biostatistics, statistics or a closely related field from an accredited university, an outstanding methods research and collaborative research publication record in the peer-reviewed literature, evidence of success in mentoring junior scientists, and evidence of professional service. Those applying for a tenure-eligible position should have an international reputation. The successful candidate should have strong communication skills to discuss scientific issues and write scientific papers. Full Federal benefits including salary, leave, health and life insurance, long-term care insurance, retirement, and savings plan (401k equivalent) will be provided. Questions about the position can be addressed by Dr. Paul Albert, Senior Investigator and Chief of BBB at 301-496-5582. Interested individuals should email a cover letter describing research interests and professional accomplishments, curriculum vitae, and the names and contact information for three references to: Adrienne Lonaberger; Program Analyst, DESPR, NICHD; 6100 Executive Blvd, Room 7B05; Rockville, MD 20852: or e-mail [email protected]. Applications received by December 15, 2010 will be considered for a first round of interviews, but applications will be accepted until the position is filled. The DHHS and NIH are Equal Opportunity Employers.

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Tenure Track Investigator Human Genetics Branch, NIMH The Division of Intramural Research Programs (DIRP) of the National Institute of Mental Health (NIMH) invites applications for a tenure-track investigator position to form a new research program focused on the functional genomics of neuropsychiatric phenotypes. The program is located within

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the Human Genetics Branch (Francis J. McMahon, Chief). The program aims to apply new genetic/genomic methods and approaches to characterize genes involved in psychiatric disorders. The ideal candidate would be interested in the biologic relevance of genetic variation involved in neuropsychiatric phenotypes. The candidate is expected to take advantage of the existing NIH infrastructure such as core facilities and to capitalize on existing intramural research resources and its scientific strengths. Applicants should 1) have a Ph.D. and/or M.D.; 2) have demonstrated the ability to make advances in neurogenetics and functional genetics in peer-reviewed original work; 3) have a growing body of high quality publications in this field; and 4) show promise to be an independent investigator. We seek candidates whose research areas match one or more of the following program aims: 1)Functional genomics - Determine the biological function of susceptibility loci for psychiatric disorders by use of genomic approaches and/or in vitro or in vivo experiments in cells or model organisms; 2) Gene regulation - Investigate patterns and control of gene expression in tissues/cells of relevance for major psychiatric illnesses; 3) Systems biology - Apply cutting-edge statistical and computational methods to genome-wide and transcriptome-wide data to elucidate the biological impact of heritable or acquired genetic variation relevant to psychiatric disease. Candidate will be provided with an attractive resource package that will include personnel and a budget to conduct this research. Salary will be commensurate with experience and accomplishments, and a full Civil Service package of benefits (including retirement, health, life, and long term care insurance, Thrift Savings Plan participation, etc.) is available. The NIMH program is located on the Bethesda, MD, campus, which offers outstanding resources and unparalleled opportunities for interdisciplinary collaborations with scientists throughout the National Institutes of Health (NIH). The NIMH is a major research component of the NIH and the Department of Health and Human Services (DHHS), which have nationwide responsibility for improving the health and well-being of all Americans. Interested applicants should send curriculum vitae, bibliography, statement of research interests (including perspectives on the relevance of their current and planned research to the etiology of mental illness and current DIRP research), accomplishments, and goals, together with three letters of reference to: Chair, Search Committee for a Human Functional Geneticist; DIRP, NIMH, NIH, Bldg. 10, Rm. 4N-222; 9000 Rockville Pike, Bethesda, MD 20892-1381; or e-mail to [email protected]. Review of applications will begin on December 1, 2010, but applications will continue to be accepted and considered until the position is filled. NIH and DHHS are Equal Opportunity Employers

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Tenure/Tenure-Track Investigator Systems Immunology and Infectious Disease Modeling, NIAID The National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), is seeking an outstanding individual for its new Program in Systems Immunology and Infectious Disease Modeling (PSIIM). Modern technology allows the deep analysis of biological systems at multiple levels. The challenge is not only to collect the large amounts of data new technologies can generate at different scales of biological organization, but also to organize it in a manner that enhances our understanding of how such systems operate. Achieving this goal requires an interdisciplinary effort, and for this reason PSIIM is organized as an integrated team of scientists

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and support staff structured in groups. These groups will have access to the latest technology for gene expression profiling, next generation sequencing, high content screening of RNAi libraries, imaging, and genomic and proteomic analysis, as well as a substantial computer infrastructure, together with modern conventional laboratory facilities for cell and animal experimentation. They will also have access to BSL-3 facilities for working with infectious agents of high priority for human health and biodefense. Although PSIIM has been established within NIAID and has an immune/infectious disease focus, it is also expected to play a major role in fostering the growth of systems biology efforts throughout NIH. PSIIM staff will interact extensively with investigators in other components of the NIH intramural research program, including but not limited to the National Center for Biotechnology Information, NIH Chemical Genomics Center, Center for Information Technology, and Center for Human Immunology, all of which have activities emphasizing systems and informatic approaches to biomedicine. Current groups in PSIIM include Immunology, Computational Biology—Modeling and Simulation, Molecular/Cell Biology—High-throughput Screening, Proteomics, and Systems Genomics. PSIIM is now recruiting for a tenure-track or tenure level team leader appointment in the following area: Transcriptional Networks and Control of Differentiation: The incumbent will be responsible for applying and, as required, developing novel experimental and computational methods for the systems-wide analysis of gene regulatory pathways and networks, with a specific emphasis on the transcription factor circuits that define cell fate and that translate extracellular signaling into cellular responses. As part of this effort, the incumbent will engage in quantitative measurements of transcription factor and gene expression, analysis of protein-DNA interactions, and assessment of the contributions of epigenetic modifications/chromatin remodeling events to regulation of the behavior of such transcriptional networks. PSIIM is especially interested in recruiting an individual with a strong interest in the application of these methods to the integration of information on cell signaling events, developmental state, and gene regulatory circuits into comprehensive models of the control of cellular differentiation, for example, of effector CD4+ T cells or iPS. This position and its research activities are fully funded by the intramural research program of NIAID. The team leader is expected to build a working group consisting of postdoctoral fellows, students, technicians, and staff scientists. The team leader will work with the program director and other PSIIM faculty to help set the goals for PSIIM and to determine how best to reach these goals as an integrated group. To ensure appropriate career trajectories for those joining the PSIIM team effort, NIH has modified its tenure policies to take specific account of contributions made in such a team science setting. Members of PSIIM will be expected to play a major role in development of an integrated computational systems approach to biology, the application of these methods to questions of substantial biomedical importance, and the dissemination of the tools and techniques developed in PSIIM across the NIH intramural program and in the extramural academic and industrial spheres. Applicants should be seeking a challenge in which creativity, technical expertise, and a strong desire to achieve in a team setting will be critical for success. Interested candidates may contact Ronald Germain, M.D., Ph.D., Program Director, PSIIM, DIR, NIAID, at 301-496-1904 or [email protected] for additional information about this position. Additional information about PSIIM is available online at www.niaid.nih.gov/LabsAndResources/labs/aboutlabs/psiim/ <http://www.niaid.nih.gov/LabsAndResources/labs/aboutlabs/psiim/> . Applicants must have a Ph.D., M.D., or equivalent degree in a relevant field with extensive

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postdoctoral experience, as well as a strong publication record demonstrating potential for creative research. To apply, submit your curriculum vitae, bibliography, and a detailed statement of how your expertise can contribute to the success of the PSIIM program to Hanh Ngo at [email protected]. In addition, three letters of reference must be sent directly from the referee to Robert Hohman, Ph.D., Chair, NIAID Search Committee, c/o Hanh Ngo at [email protected] or 10 Center Drive, MSC 1356, Building 10, Room 4A22, Bethesda, MD 20892-1356. E-mail is preferred. Applications will be reviewed starting on October 3, 2010 and will be accepted until the position is filled. Further information regarding the DIR laboratories is available at www.niaid.nih.gov/about/organization/dir/ <http://www.niaid.nih.gov/about/organization/dir/> , and information on working at NIAID is available on our Web site at www.niaid.nih.gov/careers/dps <http://www.niaid.nih.gov/careers/dps> . For more information about the NIAID systems biology program, visit www.nih.gov/catalyst/2006/06.09.01/page1.html <http://www.nih.gov/catalyst/2006/06.09.01/page1.html> . HHS, NIH, and NIAID are equal opportunity employers.

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Tenure-Track Investigator Dense Reconstruction of the Nervous System/Connectomics, NINDS The Division of Intramural Research of the National Institute of Neurological Disorders and Stroke (NINDS), NIH has begun an international search for outstanding investigators for tenure-track positions in the area of circuit/system neuroscience. In particular, we seek neuroscientists using high resolution, high-throughput imaging technologies to reconstruct the detailed structure and connectivity of nervous system circuits. The NINDS Division of Intramural Research boasts active basic, translational and clinical research programs in neuroscience, neurological disorders and stroke. These programs operate within the NIH Intramural Research Program, one of the largest and most active basic and clinical research environments in the world, and are a central component of a vibrant neuroscience community at NIH. The successful individual will initiate and direct an independent research program focused on developing and applying high-throughput reconstruction techniques to important problems in circuit function, development or degeneration. The candidate will have earned a Ph.D., MD or MD/PhD degree and will employ excellent scientific and communication skills to configure an original, productive and collaborative research program. Outstanding candidates who have established internationally recognized highly accomplished research programs may also be considered for a tenured position to build a dynamic, productive research group. Laboratory facilities, shared research facilities, research funds and salary are competitive with premier academic institutions. Applicants should send curriculum vitae, bibliography, statement of research interests, and have three letters of reference sent to: Dr. Jeffrey Diamond, National Institute of Neurological Disorders and Stroke, c/o Nhuyen Quach, Office of the Scientific Director, Division of Intramural Research, Building 35 Room GA908, NIH, Bethesda, MD 20892 or [email protected]. Applications will be reviewed beginning September 15, 2010 and proceed until successful candidates are recruited. HHS and NIH are Equal Opportunity Employers.

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Tenure-Track/Tenure-Eligible Investigator Chemical Biology Laboratory, NCI CCR The Chemical Biology Laboratory (CBL), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (DHHS) is accepting applications for the position of Tenure Track/Tenure-Eligible Investigator to develop an independent research program addressing problems at the interface of chemistry and biology. Ideal candidates will establish dynamic, collaborative programs that develop and apply chemical methods, tools and materials to define and manipulate the biological processes that impact cancer and/or AIDS. Additionally, Investigator is expected to establish an internationally recognized program and direct a research group composed of postdoctoral fellows and technicians. Of particular interest, chemists developing and implementing novel imaging tools; controlling cell fate via small molecules; and synthetic chemists developing novel methodology to enable the preparation of complex biologically active molecules. Candidates must possess a Ph.D. in Chemistry or related Physical Science. Although this search is directed at the tenure track level, outstanding candidates at the tenured level will also be considered. The position is located at the NCI campus in Frederick, MD. This location offers state-of-the-art Chemical Biology laboratories as well as core facilities including mass spectrometry; NMR spectroscopy; protein expression and proteomics; electron, optical and small animal imaging and other advanced technologies. The Incumbent will be provided with laboratory space, research equipment, staff support, and an annual supply budget. Consideration of applicants will begin September 1, 2010 and will continue until the position is filled. Salary is competitive and is commensurate with experience and full benefits (including retirement, health insurance, life insurance, and a Thrift Savings plan). This position is not restricted to U.S. citizens. To apply, please submit a cover letter, curriculum vitae, description of research plans (~ 5 pages), and arrange to have 3 letters of recommendation sent to: Ms. Deanna Dougherty, Administrative Officer, NCI-Frederick, P.O. Box B, Bldg. 578/6, Frederick, MD 21702-1201, Tel. 301-846-5199, Fax 301-846-6053, E-mail: [email protected]. PDF files are encouraged. This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs. DHHS, NIH, and NCI are Equal Opportunity Employers.

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Chief, Hematology Service Department of Laboratory Medicine, CC The National Institutes of Health (NIH) invites candidates with strong clinical, leadership, managerial and scientific credentials to apply for the position of Chief, Hematology Service, Department of Laboratory Medicine, Clinical Center, Bethesda, MD. The NIH Clinical Center is the largest hospital in the world totally dedicated to translational clinical research. This position has become available at a truly exciting time in the history of NIH. The NIH Clinical Center's Hematology Service provides clinical research support for the innovative translational clinical research programs at the National Institutes of Health, thereby offering remarkable opportunities for scientific collaboration. The Hematology Service consists of six

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sections: Automation, Special Hematology, Bone Marrow Morphology and Immunohistochemistry, Coagulation, Molecular Testing and Flow Cytometry. These sections support hematology laboratory testing for all inpatient and outpatient clinical research programs involving both pediatric and adult patients. The Service has a long standing research program directed at new methods development; and collaborative and translational research linked to Institute initiatives. In addition, the Hematology Service serves as a partner in the ACGME approved Hematology fellowship program (based in the NHLBI) and the Hematopathology fellowship program (based in the NCI). The Hematology service currently consists of 38 staff members, including four physicians (two hematopathologists and two hematologists) plus the Chief of the Service. Candidates must be a physician with board certification in pathology or hematology, with additional certification in hematopathology or extensive experience in hematopathology; and a current medical license. He/she must also have a minimum of 10 years experience in hematology and hematopathology, as well as laboratory management experience. Candidates should demonstrate prior direct involvement in research protocols with a clinical component; as well as having a record of innovative research productivity. Salary and appointment mechanism will be commensurate with laboratory hematology, hematopathology and managerial experience; as well as scientific accomplishments. Review of applications will begin on or about August 15, 2010, but applications will be accepted until this position is filled. Reply with a letter of interest, CV and the names of six references to Dr. Henry Masur, Chair, Hematology Search Committee, c/o Ms. Kathy Hilburn, CC, NIH, Bldg 10, Room 2C306, 10 Center Dr., MSC 1508, Bethesda, MD 20892 or [email protected]. The Department of Health and Human Services and NIH are equal opportunity employers. ---------------------- Link to NIH Fellowships, Staff Scientist and Tenured/Tenure-Track Research Positions https://www.training.nih.gov/ <https://www.training.nih.gov/> https://www.training.nih.gov/career_services/jobs <https://www.training.nih.gov/career_services/jobs> Link to NIH Jobs http://www.jobs.nih.gov/ <http://www.jobs.nih.gov/> Searchable database of all NIH intramural research projects http://intramural.nih.gov/search/index.tml Clinical Training at NIH http://www.cc.nih.gov/training/index.html http://www.cc.nih.gov/training/gme.html

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