plasma membrane structure and transport
TRANSCRIPT
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Phospholipid Molecules
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• The cell membrane is a phospholipid bilayer with proteins, lipids and carbohydrates.
Figure 3.3
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Colesterol 50% lípidos
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Phytosterols
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bacterial
animal
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Lipids bilayer is fluid
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• Lipids of the bilayer fluid or liquid-crystalline state• Proteins move within the membrane
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Membrana asimétrica
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Triglicéridos
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Adaptación homeoviscosa en composición de membranasde poikilotérmicos
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Figure 3.3
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• The cell membrane is a phospholipid bilayer with proteins, lipids and carbohydrates.
Figure 3.3
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Membrane Protein Synthesis
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Membrane proteins functions
Figure 3.4
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Fig. 5-10a, p. 114
Integrin
(a) Anchoring. Somemembrane proteins, suchas integrins, anchor thecell to the extracellularmatrix; they also connect tomicrofilaments within the cell.
Outsidecell
Insidecell
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Fig. 5-10g, p. 114
Insidecell 2
(g) Intercellular junction.Cell adhesion proteinsattach membranes ofadjacent cells.
Insidecell 1
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Fig. 5-10b, p. 114
Outsidecell
(b) Passive transport.Certain proteins formchannels for selectivepassage of ionsor molecules.
Insidecell
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Fig. 5-10c, p. 114
Outsidecell
Insidecell
(c) Active transport.Some transport proteinspump solutes across themembrane, which requiresa direct input of energy.
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Fig. 5-10d, p. 114
Outsidecell
Insidecell
(d) Enzymatic activity.Many membrane-boundenzymes catalyzereactions that take placewithin or along themembrane surface.
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Fig. 5-10e, p. 114
Outsidecell
Insidecell
(e) Signal transduction.Some receptors bind withsignal molecules such ashormones and transmitinformation into the cell.
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Fig. 5-10f, p. 114
Antigen
(f) Cell recognition.Some glycoproteins functionas identification tags. Forexample, bacterial cells havesurface proteins, or antigens,that human cells recognizeas foreign.
Outsidecell
Insidebacterial
cell
Antibody
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Transport across membranes
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Diffusion
Figure 3.18
• Movement of a substance from an area of high concentration to low
• Concentration gradient and electrochemical potential• (down and up the gradient)
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Diffusion across the Cell Membrane
Figure 3.19
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Cystic fibrosis transmembrane conductance regulator
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Osmosis
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Figure 3.20
Osmotic Pressure
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Transport across the membrane
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Passive TransportFacilitated Diffusion
Permeases
Figure 3.22
Uniport
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Efecto alostérico y especificidad
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Figure 3.23
Active Transport
Antiport
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Gradientes de concentración
Gradientes electroquímicos
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Figure 3.24
Secondary Active Transport
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symport
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