Planning, Priority Setting, and Budget

Development for NIH AIDS Research

Robert W. Eisinger, Ph.D. Office of AIDS Research

National Institutes of Health

Focus of Presentation

• Overview of OAR

• Priority Setting Process

• Budget Development Process

• Trans-NIH Management, Coordination, and

Evaluation

National Institute

on Alcohol Abuse

and Alcoholism

National Institute

of Arthritis and

Musculoskeletal

and Skin Diseases

National Cancer

Institute

National Institute

of Diabetes and

Digestive and

Kidney Diseases

National Institute

of Dental and

Craniofacial

Research

National Institute

on Drug Abuse

National Institute

of Environmental

Health Sciences

National Institute

on Aging

National Institute

of Child Health

and Human

Development

National Institute on

Deafness and Other

Communication

Disorders

National Eye

Institute

National Human

Genome Research

Institute

National Heart,

Lung, and Blood

Institute

National Institute

of Mental Health

National Institute

of Neurological

Disorders and

Stroke

National Institute

of General

Medical Sciences

National Institute

of Nursing Research

National Library

of Medicine

Center for

Information

Technology

Center for

Scientific Review

National Center

for Complementary

and Alternative

Medicine

National Institute

of Allergy and

Infectious Diseases

John E. Fogarty

International

Center

National Center for

Advancing

Translational

Sciences

Warren Grant

Magnuson

Clinical Center

National Institute on

Minority Health and

Health Disparities

National Institute of

Biomedical Imaging

and Bioengineering

Office of the Director

Office of AIDS

Research

DHHS/NIH/OD/OAR

National Institutes of Health

NIH Office of AIDS Research

• Unique role and legislative authorities

• Annual trans-NIH strategic plan

• Annual trans-NIH budget tied to the strategic

plan

• Trans-NIH coordination, management, and

evaluation

• A unified NIH research front against the AIDS

pandemic

Annual Trans-NIH Strategic Plan: Setting

Scientific Priorities

Trans-NIH Plan for HIV-Related

Research

OAR Planning Process

Trans-NIH Coordinating Committees

NIH Institutes and Centers

Other government entities with research responsibilities

Non-government experts from academia, foundations,

and industry

Community representatives

OAR Advisory Council

Uses of the Annual Strategic Plan

Informs the scientific community, the public, and

AIDS-affected communities about the Trans-NIH

AIDS research agenda

Frames the development of the Trans-NIH AIDS

budget

Determines the use of NIH AIDS-designated dollars

Coding permits tracking and monitoring of

expenditures

Strategic Plan Areas:

Investing in Basic Research

- Etiology and Pathogenesis

Reducing New Infections

- Microbicides

- Vaccines

- Behavioral and Social Science

- Treatment as Prevention

Improving Disease Outcomes for HIV-

Infected Individuals

- Drug Discovery, Development, and Treatment

- Research Toward a Cure

Strategic Plan Areas:

Reducing HIV-Related Disparities

Special Populations:

- Racial and Ethnic Populations

- Women and Girls

- Research in International Settings

Training, Infrastructure, and Capacity Building

Translating Research From Bench to Bedside

to Community

- Natural History and Epidemiology

- Information Dissemination

NIH AIDS Research

Overarching Priorities

A strong foundation of basic science

Prevention research, including

development of vaccines, microbicides,

and behavioral interventions

Research toward a cure

Current NIH Objectives in Behavioral

and Social Science Research

Preventive Intervention Research

Basic Behavioral and Social Science Research

Consequences of HIV Infection

Research Methods

Behavioral and Social Science

Research Portfolio

Adherence/compliance/retention in care

Stigma, discrimination, poverty, criminal justice

Neurocognitive complications

Drug and alcohol use; drug interactions

Integrate BSSR into design and evaluation of interventions

Develop and test innovative interventions reflecting the cultural and social context of the lives of various populations

Trans-NIH Budget Development Process

Budget Development Process

Institutes and Centers (ICs) develop new/expanded program initiatives, with budget requests, for each scientific area

OAR reviews ICs’ initiatives in relation to the Plan and OAR priorities

Consultations between ICs and OAR throughout process

Budget is developed in consultation between the OAR Director and NIH Director

OAR allocates budget levels to each IC

$2,921 $2,902 $2,906 $2,928 $3,019 $3,085 $3,059 $3,075 $3,095

$2,898

$3,122

50

550

1050

1550

2050

2550

3050

3550

2005 2006 2007 2008 2009 2010 2011 2012 2013

CR

2013

PS

2014

PB

Doll

ars

in

Mil

lio

ns

Fiscal Year

Total AIDS Funding

FY 2005 – FY 2014

IC Funding Distribution FY 2012-2014 (dollars in thousands)

DHHS/NIH/OD/OAR

FY 2014

Institute / FY 2012 FY 2013 President's

Center Actual CR Budget

NCI $271,692 $273,355 $278,101

NHLBI 67,995 68,431 60,982

NIDCR 20,061 20,301 17,130

NIDDK 30,951 31,140 30,136

NINDS 46,857 47,144 47,229

NIAID 1,572,973 1,583,052 1,631,577

NIGMS 65,202 65,601 69,597

NICHD 144,924 146,189 152,923

NEI 8,902 8,956 --

NIEHS 5,338 5,371 5,122

NIA 5,632 5,666 5,888

NIAMS 4,925 4,955 5,455

NIDCD 1,877 1,888 1,888

NIMH 190,387 191,733 163,264

NIDA 319,292 321,347 332,286

NIAAA 28,380 28,554 29,378

NINR 12,642 12,719 12,809

NHGRI 7,130 7,174 7,120

NIBIB 3,699 3,722 1,287

NIMHD 20,446 20,571 21,331

NCCAM 1,610 1,620 1,610

NCATS 68,328 68,766 66,417

FIC 24,241 24,389 27,017

NLM 7,665 7,712 8,412

OD

OAR 63,802 64,192 64,392

ORIP 79,844 80,333 80,365

Subtotal, OD 143,646 144,525 144,757

TOTAL, NIH $3,074,795 $3,094,881 $3,121,716

FY 2014 Funding by Scientific Area of

Emphasis of the NIH Plan for HIV-Related

Research (dollars in thousands)

FY 2012 FY 2013 FY 2014

Area of Emphasis Actual CR PB

HIV Microbicides $129,919 $134,627 $133,800

Vaccines 556,613 560,962 574,966

Behavioral and Social Science 420,084 421,684 430,209

Therapeutics

Therapeutics as Prevention 56,561 58,126 66,026

Drug Discovery, Development and Treatment 650,059 659,261 651,168

Total, Therapeutics 706,620 717,387 717,194

Etiolgy and Pathogenesis 668,244 674,697 693,851

Natural History and Epidemiology 257,973 253,342 247,385

Training, Infrastructure, and Capacity Building 280,775 281,474 272,062

Information Dissemination 54,567 50,708 52,249

Total, Budget Authority $3,074,795 $3,094,881 $3,121,716

Trans-NIH Management

and Coordination

Facilitate trans-institute programs

Manage multi-institute research

– Centers for AIDS Research (CFAR) Steering

Committee

Foster research through designated funds, targeted

workshops

Identify areas that require focused attention

Tracking AIDS Research Funds

All ICs are required to code all NIH-funded intramural

and extramural AIDS-related research projects

All projects coded to objectives of the Plan

Information includes:

– Principal Investigator

– Institution

– Funding

– Mechanism

ARIS data uploaded to RCDC

Overview

OAR has and continues to shift AIDS research

program priorities and resources to meet the

changing epidemic and scientific opportunities

This investment in AIDS research has produced

critical scientific advances

AIDS research has also assisted prevention and

treatment of other important diseases

New challenges and opportunities lie ahead

Additional Information

Additional information is available

on the National Institutes of Health

Office of AIDS Research

Web site

http://www.oar.nih.gov

NIH… Turning Discovery Into Health®