pink science

Cancer made me realise I wanted

more from life

TAKEACTION! Find out how you can get involved in Breast Cancer Awareness Month

TIME TO REMEMBER

We celebrate the lives of two of our most inspiring supporters

PLUS Your letters and pictures, Girls vs Boys, the latest policy news and diary

BREAST CANCER CAMPAIGN MAGAZINE / AUTUMN 2012

PINKSCIENCE

IMPROVING TREATMENT

How one of our grant- supported projects could hold the key to more effective chemotherapy

YOUR SUPPORT IS HELPING FUND

RESEARCH INTO TREATMENT

CHOICES AND FERTILITY

GET TO KNOW US

OUR MISSION

Everything we do at Breast Cancer

Campaign is focused on one thing:

beating breast cancer. The charity

is bringing its unique community

of supporters, scientists and those

touched by breast cancer closer

through a new way of thinking:

Pink Science. It sums up the charity’s

pioneering approach to breast

cancer research, which identifies

and funds the research projects

with the greatest potential to save

and improve lives – and, ultimately,

find a cure for breast cancer.

HOW WE SPEND YOUR MONEY

Today, the charity supports 92

research projects, with combined

funding of almost £16 million, in 36

centres of excellence across the UK

and Ireland. All our donations come

from the fundraising efforts of

people like you – thank you. Over

the past 16 years, the charity has

awarded 367 grants with a total

value of £40 million to universities,

medical schools and research

institutes. And the figures are rising.

UNDERSTANDING PINK SCIENCE

We chose a jigsaw piece as our logo

because it symbolises the missing

piece of the puzzle that is the cure

for breast cancer. Everyone can be

part of Pink Science; not just the

scientists whose work we fund but

also our supporters and, of course,

those touched by breast cancer.

47,700women diagnosed

with breast cancer

every year

12,000women who die

from breast cancer

every year

80%of women diagnosed

with breast cancer

today will still be

DOLYH�LQ�¿YH�\HDUV

1 in 8chance a woman will

get breast cancer in

her lifetime

3years between

screening invitations

for women aged

50 to 70

340men diagnosed with

breast cancer every

year – it proves fatal

for around 80

£40million

TOTAL WE HAVE AWARDED

IN GRANTS TO FUND

BREAST CANCER

RESEARCH IN THE

PAST 16 YEARS

TO FIND OUT MORE PLEASE VISIT OUR WEBSITE

BREASTCANCERCAMPAIGN.ORG OR CALL OUR

SUPPORTER CARE TEAM ON 020 7749 4114

JOIN OUR FACEBOOK GROUP

OR FOLLOW US ON TWITTER

@BCCAMPAIGN

BREAST

CANCER

FACTS

Pink Science

covers every

aspect of breast

cancer research.

Its eight themes

mirror the cancer

journey, making

Pink Science

accessible and

relevant to all.

Prevention

Treatment

Emotional

Education

Biology

Genetics

Diagnosis

Growth

WHAT DO THE PINK ICONS MEAN?F

igure

s r

ela

te to U

K a

nd a

re c

orr

ect at tim

e o

f goin

g to p

ress

WE CAN ALL BE

PART OF THE CUREWelcome to the Breast Cancer Awareness Month issue of

Pink Science. This October we’re calling on everyone to turn

awareness into action and BE PART OF THE CURE. From

taking part in wear it pink to buying one of our Pink Picks –

including items from Asda’s Tickled Pink and Debenhams’

Think Pink ranges, Zandra Rhodes and nails inc. – there are

lots of ways to get involved.

Thanks to your incredible support we have already granted

£40 million to various research teams throughout the UK

and Ireland. You can read about the work of Dr Jeremy

Blaydes on page 14, and there’s an update from Dr Jo Morris,

Dr Richard Grose and Dr Jenny Gomm on pages 16-17 – just

a few examples of our pioneering breast cancer research.

Also in this issue, we remember two friends of the charity,

Emma Freeborn and Kirste Bowman, who both sadly passed

away earlier this year. You can’t help but be inspired by the

stories of these wonderful women on pages 24-25.

As always, awareness and action remain critical in beating

breast cancer. We can all BE PART OF THE CURE this October.

Baroness Delyth MorganChief Executive, Breast Cancer Campaign

PINK SCIENCE is produced by Northstar (thisisnorthstar.com) for Breast Cancer Campaign. Project Editor Emma Barlow Deputy Project Editor Lisa Paul Designer Pippa Hester Group Project Editor Robin Swithinbank Group Art Director Matt Warner Group Production Editor Andy Tidball Production Manager Helen Craig Managing Director Mark Beazleigh. For Breast Cancer Campaign: 0HGLD�5HODWLRQV�2I¿FHU�Isabel Monk

04-11 Notebook

Find out how you can get

involved in Breast Cancer

Awareness Month, including this

year’s Big Pink Jump. Plus, our

latest news and policy updates

12-13Fundraising

We meet Campaign super

supporter Gerard Varin, who

ran an incredible 806 miles

from Derbyshire to Switzerland

in the name of charity

14-17Research

Dr Jeremy Blaydes discusses

his team’s research, which

could hold the key to preventing

resistance to chemotherapy. And

we present a trio of scientists

working towards a cure

18-23Against the odds

Read the miraculous story

of Carly Gibson, who went on

to have two children after being

diagnosed with breast cancer,

aged just 29

24-25We remember

We look at the lives of two

of our most inspirational

supporters, Emma Freeborn

and Kirste Bowman

26-31Pink pages

Browse fab products in Pink

Picks. Plus, your letters, a tasty

treat, our gallery and key dates

Inside this issue

[ W E LC O M E ] 03

BREASTCANCERCAMPAIGN.ORG

N OT E B O OKBREAST CANCER CAMPAIGN NEWS FROM AROUND THE UK

TIME

TO TAKE

ACTION There are lots of ways to get involved in Breast Cancer Action Month…

October has traditionally been

the month we’ve called

Breast Cancer Awareness Month,

but this year we are repositioning it

as Breast Cancer Action Month! We

are calling on all of our supporters

to take action to help us continue

funding more groundbreaking

breast cancer research.

From wearing it pink with friends,

to jumping out of a plane for The

Big Pink Jump – there are so many

ways that you can get involved and

BE PART OF THE CURE.

And this year’s wear it pink on

26 October is extra special as we

celebrate its 10th anniversary.

We’ve set our sights on raising

£2 million, which will take the total

raised to a whopping £25 million!

So register today and wear it pink

to work or school – or invite a group

of your friends to come round and

have a wear it pink Big Night In.

To help make your wear it pink

event a success, Mary Berry has

shared her pink macaroon recipe

with Pink Science readers – see

page 29. And you can toast your

fundraising efforts with Levi Roots’

special pink mocktail (opposite).

Plus, don’t forget you can order

your pink Breast Cancer Campaign

vest from Damart – £4 from each

sale will be donated to Campaign.

With your help we can make 26

October the biggest wear it pink yet!

STAR SUPPORT

Chris Cracknell, England Rugby Sevens player, wears it pink

[ N O T E B O O K ] 0 5


RASPBERRY & PINEAPPLE LEMONADE

PAINT YOUR

PINKIE PINK

PRETTY IN PINK

TV star Kate Thornton (below)

models Damart’s vest – £4 from

each one sold goes to Campaign

CAPED CRUSADERS

wear it pink and join

Breast Cancer Campaign’s

community of scientists,

supporters and breast

cancer survivors –

our superheroes

Start the party with a mocktail by Levi Roots Levi Roots can usually be found

singing about his famous Reggae

Reggae sauce, but this October he’s

designed a mocktail recipe for your

wear it pink Big Night In.

Remember to ask your guests for

a £5 donation – it’s never been more

fun to raise money for Campaign...

Put 450g raspberries and 4tbsp of

sugar in a bowl. Stir gently, cover and

set aside for one hour. Transfer to a

food processor and blitz to a purée.

Push the mixture through a sieve,

mix in the juice of 10 limes, 250ml

pineapple juice and 1 litre soda water.

Add sugar to taste and serve with ice.

We’ve joined up with leading

beauty brand nails inc. to produce

a pink sparkly nail varnish to raise

vital funds and awareness this

Breast Cancer Action Month.

We are asking everyone

to follow model Poppy

Delevigne (right) and paint

their pinkie nail pink to show

the world that they have

been part of the action.

mani-cure

Taken from ‘Sweet’ by Levi Roots, published by Mitchell Beazley

06 [ N O T E B O O K ]


You could help us to get Breast

Cancer Action Month off to

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so sign up now to take part in an

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and raise funds for vital research.

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raise awareness and funds for

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to take action and help us to fund

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we will BE PART OF THE CURE.

JUMP INTO

ACTION Why not unleash your inner daredevil and take part in our Big Pink Jump for Breast Cancer Action Month

There is one small and important action we can all take this month

Whether you help Paint the

Town Pink, wear it pink, or

Paint your Pinkie Pink this

October, you will be part of

our mass action to help beat

breast cancer. But don’t forget

there is one small action you

can do that is perhaps the

most important, and that’s to

be breast aware and check

yourself regularly. A brief

routine check can be crucial

in catching the disease early.

So stay healthy and follow our

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BEBREAST

AWARE

HOW TO BE PART OF THE ACTION

SUPPORTRESEARCH

CAMPAIGN WITH US

08 [ N O T E B O O K ]


FUNDRAISER OF

THE YEAR

Kevin Hunt

RAG OF THE YEAR Loughborough Students RAG

WEAR IT PINK

FUNDRAISER Veolia Environmental Services

COMMUNITY

AMBASSADOR

Shirley Hallam

Sheila Weightman

CONTRIBUTION TO

RESEARCH

Campaign Tissue Bank

RESEARCH TEAM

OF THE YEAR

Dr Jeremy Blaydes and his team

OUTSTANDING

CONTRIBUTION Nottingham Karnival

Manchester and Salford

Regional Group

REGIONAL GROUP

Pink on Wight

SCHOOL OF THE YEAR

Pembridge Hall School

OUTSTANDING

CORPORATE PARTNERS

Asda, Pentel, Vanish

THIS YEAR’S WINNERS ARE...

Whether running, walking, holding collections or fundraising events, our supporters know how to put the fun into fundraising. Here we say thanks to just a few of them

FUNDRAISERS GO FOR IT

We celebrated the inspiring

work done by supporters and

researchers at our sixth annual

awards reception, which was held

at the House of Lords in May.

There were 14 winners in all,

from individual fundraisers such

as Kevin Hunt, who featured on

the cover of the spring issue of

Pink Science, to some of our

corporate partners including

Asda, Pentel and Vanish.

Two groups were also

presented with an award for their

outstanding and continued support

of Breast Cancer Campaign.

Nottingham Karnival, Nottingham

University’s student RAG group

(above), have been supporting

us for 16 years, and have raised

more than £300,000. And the

work of the Manchester and

Salford Regional Group was also

recognised. They’ve raised more

than £44,000 so far.

A big well done to everyone –

we hope you enjoyed the night.

AWARDS AT THE

HOUSE OF LORDS

KARNIVAL SPIRIT

The Nottingham

group with their prize

[ N O T E B O O K ] 09


We had a brilliant day back in

May when our supporters got

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vs Boys 5k race. It was a very close

call, with both genders putting in a

great effort, but it was the girls that

came out on top. Congratulations!

Simon Hughes MP (pictured right,

with Delyth) supported the event.

+H�VD\V��μ3HRSOH�UDQ�*LUOV�YV�%R\V��

to remind others that more than half

a million people in this country have

had breast cancer and 12,000 die

from it every year. But by funding

UHVHDUFK��ZH�FDQ�¿QG�D�FXUH�¶

Who are the Freemasons?

The Order of Women

Freemasons is the oldest and

largest Masonic organisation

for women in this country.

It was established in 1908 and

works on the same lines as

male freemasonry. Freemasonry

is concerned with moral and

spiritual values, and we like to

do philanthropic things for

national and local charities.

How many members are there?

We have 6,000 members in the

United Kingdom, Australia,

Canada, South Africa, Spain and

Zimbabwe. They are grouped

into over 300 Craft Lodges

operating under a Grand

Master and Grand Lodge.

Is there a ‘typical’ member?

There isn’t a typical type of

person and they come from all

walks of life. This is one of the

nicest aspects of freemasonry

– we welcome women of any

race or faith. You can apply to

join us on our website.

Why Breast Cancer Campaign?

As a female organisation, one

in eight of us will get breast

cancer, and we all know people

who have been affected by this

disease. We wanted to help

women in the future – we’d urge

other groups to do the same.

7R�¿QG�RXW�PRUH�DERXW�

7KH�2UGHU�RI�:RPHQ�

)UHHPDVRQV��YLVLW�RZI�RUJ�XN

THANK YOU

ON YOUR MARKS...

(Left) Celebrity supporters Chris

Cracknell and Sarah Maxwell line

up at the start line

The Order of Women Freemasons have donated £150,000 to Campaign. Zuzanka Penn and Sylvia Major told Pink Science why they want to BE PART OF THE CURE

GIRLS VS BOYS

Take the challenge

12 [ F U N D R A I S I N G ]


Gerard Varin knew a number

of women who had breast

cancer, and had been

thinking about how he could help.

But it was after one of his closest

friends, Tracey Williams, was

diagnosed that Gerard knew he

had to do something.

But rather than raise funds by

signing up for a marathon or local

running event, this father of four set

his own challenge. He decided to

run ‘Home to Home’ – a staggering

800-mile trip through Europe, from

KLV�KRPH�LQ�'XI¿HOG��LQ�'HUE\VKLUH�WR�

the village of Seleute in Switzerland,

where he was born.

Gerard said goodbye to his wife

Helen and four children and set off

on 1 April, with the aim of completing

his challenge in only one month.

Tracey, who inspired the trip,

said: ‘I was really poorly, and Gerard

said that he felt helpless when he

couldn’t make me feel better. So

he decided to raise as much

money as he could.’

Gerard ran most of the journey

alone but was joined occasionally

by family and friends, and by

others who had heard about his

challenge and wanted to show

their support for Gerard and the

cause. Members of the Round

Table helped by offering free

accommodation along the way,

and chartered physiotherapists

volunteered to be on call whenever

he needed them.

Gerard arrived at the village of

Seleute one month later, on 1 May –

he had completed the equivalent of

a marathon a day and raised more

than £35,000 for the charity.

Gerard told Pink Science: ‘It was

hard to believe that after 31 days I’d

A HOMERUN FORRESEARCHAt Breast Cancer Campaign we are lucky to have the support of extraordinary people like Gerard Varin. He went the extra mile – or 806 to be exact – in a mighty run across Europe, from his hometown in Derbyshire to his place of birth in Switzerland

Dedication

[ F U N D R A I S I N G ] 13


DFWXDOO\�¿QLVKHG��7KHUH�ZHUH�

times I thought I couldn’t run

another day, but I received

tremendous support both at

home and from people I met

along the way, which kept me going,

especially at the lowest times.’

‘I’m glad to have raised all this

money for Breast Cancer Campaign,

but now I really appreciate having

the time to put my feet up and

relax!’ he told us.

And Tracey is clearly very proud

of her friend, who went more than

the extra mile. ‘The money he

has raised will do so much for the

hundreds of women diagnosed with

breast cancer every day,’ she said.

‘He’s done a spectacular job.’

To read more about Gerard’s

H[WUDRUGLQDU\�FKDOOHQJH�RU�¿QG�RXW�

how to donate, visit his website –

anglo-suisse.net

Whether you want to run one mile, or 800 like Gerard, there’s

an active fundraising event for everyone. For inspiration, visit

breastcancercampaign.org and click on BE PART OF THE CURE

BE PART OF THE CURE

iron man

Gerard ran the

equivalent of a

marathon a day

on his incredible

journey from

Derbyshire to

Switzerland

START

DUFFIELD,

DERBYSHIRE

FINISH

SELEUTE,

SWITZERLAND

PARIS

BRUSSELS

LUXEMBOURG

CITY

IT’S 800 MILES FROM

HO

ME

TO

HO

ME

, AN

D IT

T

OO

K G

ERAR

D 3

0 D

AYS TO R

UN

!

14 [ R E S E A RC H ]


Photo

gra

phy: C

harlie

Cam

pbell

Working together for winning results

RESEARCHING THE CURE

Based at the Cancer Sciences Unit

at the University of Southampton,

Dr Jeremy Blaydes and his team

(pictured opposite) absolutely know

the value of working together.

‘Increasingly in science we are working

collaboratively,’ says Dr Blaydes, ‘because

if you’ve got something that you think is going

to make a difference, you work with the people

who are going to make that happen.’

We celebrated this in May when they

were named Breast Cancer Campaign’s

Research Team of the Year 2011

at our annual awards reception

held at the House of Lords.

This prize-winning team has

completed two three-year grants

from Breast Cancer Campaign

and is now in the midst of its third.

All of the research has focused

on molecules called C-terminal

binding proteins (CtBPs).

CtBPs are found in all cells, but

Dr Blaydes has discovered they

become particularly important

in cancer cells. ‘We know that in

cancer cells a type of molecule

called a metabolite makes these

CtBPs come together in pairs, which actually

helps cancer cells to grow and survive,’ he says.

Dr Blaydes had a background in CtBPs

before moving to Southampton in 2000 to

set up a research group. He hopes the work

they are doing could play a major part in

solving one of the biggest problems in

treating breast cancer – patients developing

a resistance to chemotherapy.

Chemotherapy is an extremely important

treatment for many types of breast cancer,

but for around 40 per cent of patients it

eventually ceases to be effective.

Dr Blaydes’ team has tested how integral

CtBPs are to chemotherapy. ‘We found if you

take away the CtBPs from breast cancer cells

and then combine that with chemotherapy,

breast cancer cells die much more quickly,’

he explains. ‘Chemotherapy damages DNA

but CtBPs keep these cells with DNA

damage alive,’ he continues.

This groundbreaking work is an example of

the sort of project that might not be possible

without funding from Breast Cancer Campaign.

‘Campaign has just been fantastic in backing

us,’ Dr Blaydes says. ‘We didn’t

really know where our research

was going to go and the funding

from Campaign has taken us

through to where we are now.’

The team is currently focusing

on ways to split these conjoined

CtPBs apart using potential lead

compounds – or drugs. When

Pink Science visited them in

the lab, the team had just made

something of a breakthrough.

‘We make CtPBs so they are

present on their own and then

we add the metabolite, which

makes them pair up,’ says

Dr Blaydes. ‘We’ve just discovered that when

we add our drug, those pairs break up again,

which is very exciting to see.’

It’s a really important result, and takes the

team a step closer to improving breast cancer

treatment. ‘The goal is always to try to make

a difference, and we’re trying to do something

that is going to make life better for patients

with breast cancer,’ Dr Blaydes says. ‘There

are many areas we could work on but we’ve

made a decision and now we have to go for it.

‘I’m pretty convinced so far with what we’ve

done that we’re on the right track.’

DR JEREMY BLAYDES AND HIS TEAM COULD HOLD THE KEY

TO STOPPING PATIENTS’ RESISTANCE TO CHEMOTHERAPY

WE’RE DOING

SOMETHING

THAT IS GOING

TO MAKE LIFE

BETTER FOR

PATIENTS WITH

BREAST

CANCER

“

”

[ X X X X X X ] 0 0

WWW.BREASTCANCERCAMPAIGN.ORG

Dr Jeremy Blaydes

and his team were

named Campaign’s

Research Team of

the Year 2011

16 [ R E S E A RC H ]


Supporting innovative science

The discovery of BRCA mutations and the part they

play in inheriting an increased risk of breast cancer

has been revolutionary, but there’s a lot to learn about

how these mutations increase the risk of breast cancer.

Dr Jo Morris is an expert in BRCA gene mutations

and has received funding from Campaign since 2006,

when she was awarded a prestigious fellowship grant.

Now Dr Morris and her team are focusing on one

of the most common mutations in the BRCA1 gene –

a mistake in a piece of protein called ‘RING’. All previous

studies into how this mistake in RING might cause

breast cancer have been inconclusive.

So Dr Morris will be modifying normal, non-cancerous

breast cells in the lab so they produce the mutated

BRCA1 protein. This resource will not just support

Dr Morris’s research but will enable researchers to study

how the BRCA1 RING controls the way in which breast

cancer cells respond to therapies, and could even lead

to the development of new treatments.

The trillions of cells in our bodies talk to each other

all the time so they know when to grow, move and

mature. They do this by using signalling molecules, such

as Fibroblast Growth Factors, which work by binding

to cell surface receptors. One such surface receptor

is FGFR1, and it’s these, and their effect on breast

cancer cells, that Dr Richard Grose is investigating.

His research has found an entirely new way that

FGFR1 can signal in breast cancer cells – a part of the

receptor is not acting at the cell surface but is rather

moving inside the cell. He has shown how this changes

the level of different proteins and actually controls the

movement and spread of cells in breast cancer.

Now Dr Grose is aiming to continue his work by

investigating what controls this portion of FGFR1 moving

inside the cell, and how the genes that FGFR1 switch on

contribute to the movement of breast cancer cells.

It could lead to new ways of treating breast cancer,

and possibly prevent breast cancer from spreading.

SPREAD OF BREAST CANCER

BRCA1 CELL DEVELOPMENT

RESEARCH UPDATEWe look at a trio of scientists whose groundbreaking work is

supported by funding from Breast Cancer Campaign

NAME:

Dr Richard Grose spEcialty:

Cancer Cell BiologyUNIVERSITY:

Barts Cancer InstituteRESEARCH:

Fibroblast Growth Factors

£40 MILLION

367 GRANTS

48,000 PEOPLE

are diagnosed in the UK each year,

which is why we must continue

to invest in groundbreaking

UHVHDUFK�WR�¿QG�D�FXUH

have been awarded to some of the

UK’s leading scientists, which

has enabled us to improve our

understanding of breast cancer

is the total amount that we have

awarded in grants throughout the

UK and Ireland so our scientists

can BE PART OF THE CURE

NAME:

Dr Jo Morris spEcialty:

Breast Cancer PredispositionUNIVERSITY:

University Of BirminghamRESEARCH:

BRC gene mutations

18 [ FA M I LY M AT T E R S ]


I dealt with having cancer because the fear of not having any children was much worse

“

”WORDS Emma Barlow

PHOTOGRAPHY Charlie Campbell

[ FA M I LY M AT T E R S ] 19

WWW.BREASTCANCERCAMPAIGN.ORG



f, in 2004, someone had told Carly

Gibson that in eight years’ time she

would not only be alive and well but

also married with two beautiful children,

she wouldn’t have believed them.

Back then, life for Carly had taken

a bad turn. Aged only 29, she found

a small lump, and was diagnosed

with ER+, HER2+ breast cancer.

ER+ or oestrogen receptor positive breast cancers

are stimulated to grow and spread by the hormone

oestrogen, which attaches to receptors on the surface

of cancer cells. Carly’s cancer was also HER2 positive,

meaning the cells had extra copies of the protein HER2

which stimulated her cancer to grow even more.

‘My world was absolutely ripped apart,’ says Carly,

who lives near Bristol. ‘I was nearly 30 years old and

moving back in with my Mum and Dad, my boyfriend

had left me and I had cancer – everything was awful.’

Like the thousands of young women diagnosed with

breast cancer every year, Carly worried about the future

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able to have children.

&DUO\¶V�GRFWRUV�UHFRPPHQGHG�ZDLWLQJ�¿YH�\HDUV�DIWHU�

being treated for breast cancer before getting pregnant,

to ensure the treatment had been successful and the

cancer wouldn’t come straight back. For Carly this would

mean waiting until her late 30s, and, because of the

hormone-blocking treatments used to treat her ER+

cancer, there was a chance of her body starting an

early menopause.

‘I dealt with having cancer because the fear of not

having any children was much worse,’ Carly explains.

‘That seemed more hopeless than the cancer coming

back. It sounds crazy but that’s how I felt.’

Fertility and breast cancer is an area that has recently

become a focus of Campaign’s research. A study

by Professor Ros Corney (see page 23) has

investigated the psychological effect it can have

on women. Reassuringly, evidence has shown that

becoming pregnant after being treated for ER+ breast

cancer does not reduce a woman’s chances of

long-term survival.

Carly underwent a lumpectomy and had her lymph

nodes removed – and it was a huge relief to

¿QG�WKDW�WKH�FDQFHU�KDGQ¶W�VSUHDG��7KH�GRFWRUV�

prescribed anti-oestrogen drugs tamoxifen and Zoladex

(which work by blocking oestrogen from attaching to

the receptors, and suppressing the body’s production

of oestrogen, respectively) as well as radiotherapy

For young women like Carly Gibson, one of the hardest things about having breast cancer is coming to terms with its effect on their fertility

I

HAPPY FAMILYCarly thought she

may never have children after

being diagnosed with ER+ breast cancer



W WHAT IS OESTROGEN RECEPTOR POSITIVE CANCER?

How a normal breast tissue cell compares to an ER+ breast cancer cell

OESTROGEN RECEPTOR POSITIVE

(ER+) BREAST CANCER CELL

In an ER + breast cancer cell there

are more of these receptors so more

signals are sent to the nucleus,

which encourages the cancer cell to

survive and multiply

NORMAL CELL

This is a view of a normal breast

tissue cell. Oestrogen latches on

to oestrogen receptors and sends

signals to the cell nucleus

and chemotherapy for Carly. The recommendation of

chemotherapy was yet another blow as it meant there

ZDV�D�VLJQL¿FDQW�FKDQFH�WKDW�VKH�ZRXOG�QRW�EH�DEOH�WR�

have children at all.

‘It was a wake-up call. I suddenly thought, what have

,�EHHQ�GRLQJ"�,�KDG�SXW�P\�FDUHHU�¿UVW�±�,�ZDV�DQ�HYHQWV�

manager and always busy – and I could feel the life

I wanted slipping away,’ Carly says.

So after a lot of discussion with her family and her

doctors, Carly made up her mind. She would not get

the chemotherapy but agreed to have Zoladex and

WDPR[LIHQ�IRU�¿YH�\HDUV��DQG�H[WUD�UDGLRWKHUDS\�

Then came some positive news. She met Chris

Gibson in May 2005 and by Christmas 2006 the couple

had moved to Portugal. ‘We quit our jobs and had some

WLPH�RXW��,�KDG�¿QLVKHG�P\�UDGLRWKHUDS\�EXW�KDG�WR�KDYH�

=RODGH[�LQMHFWLRQV�LQ�3RUWXJDO��,�ÀHZ�KRPH�IRU�FKHFN�XSV�

but other than that I was so happy and healthy.’

The couple were married in October 2007 and, before

WKHLU�KRQH\PRRQ��&DUO\�ÀHZ�KRPH�WR�VHH�KHU�RQFRORJLVW��

‘I said, “I know we agreed I’d have the hormone

WUHDWPHQWV�IRU�¿YH�\HDUV�EXW�DFWXDOO\�,�GRQ¶W�WKLQN�

I want to!” They were really good about it,’ she says.

But the doctors were not sure how her body would

react to having a baby. They told her that it could take

Oestrogen receptor

Signal

Oestrogen

KEY

NORMAL ER+ BREAST CANCER


THROUGH THE

GENERATIONS

Carly’s mum Pat and daughter Lydia will always know of the

risk of breast cancer

[ X X X X X X ] 0 0


Thanks to your support, our research is helping young

women with breast cancer like Carly. To BE PART OF

THE CURE, visit breastcancercampaign.org

BE PART OF THE CURE

A lthough rarer in young women, breast

cancer can develop at any stage in a

woman’s life. When it does, it leaves a lot of

young women, like Carly, not only having to

come to terms with having the disease but

also worrying about whether or not they will

be able to have children in the future.

Professor Ros Corney from the School

of Psychology and Counselling at the

University of Greenwich is an expert in

health psychology. With funding from

Breast Cancer Campaign, she has been

studying the psycho-social issues faced

by young women with breast cancer who

haven’t had children.

Professor Corney interviewed 20 women

who were aged between 20 and 41 when

they were diagnosed with breast cancer.

In some instances she also spoke to the

women’s partners. She found that most

of the women were worried about fertility,

especially those who were not using

assisted reproductive techniques (ARTS)

such as freezing eggs or embryos to use

in IVF later.

Her study found that the emphasis placed

on fertility issues varied considerably from

hospital to hospital, and many of the women

felt they had not been given adequate

information on the impact their treatments

could have on fertility. Single women in the

group were even less likely to have their

fertility needs considered.

Only 11 of the women were asked by

health professionals if they would like to

undergo ARTS. And nearly all of the women

worried if pregnancy could make their cancer

come back, and whether their children

would have a higher risk of getting cancer.

At the end of her study, Professor Corney

made some key recommendations including

separate consultations focusing on

IHUWLOLW\��OHDÀHWV�IRU�\RXQJHU�ZRPHQ�RQ�DOO�

aspects of breast cancer and routine

counselling for young women with the

disease. It’s clearly an area where more

work needs to be done. At Campaign, we

hope to support more vital research like

Professor Corney’s in the future.

PROFESSOR ROS CORNEY

HELPING YOUNG

WOMEN WITH

BREAST CANCER

“

”

up to a year for the hormones to settle down and were

seriously concerned the cancer could then come back.

But Carly weighed up the risks, and by the time she and

Chris returned from their honeymoon, she was pregnant.

After Lydia was born in 2008, Carly took her

into the hospital in Bristol where she had been

receiving treatment. ‘That was really emotional,’

she says. ‘All the nurses came over crying and I was

crying. It was a really special thing.’

The doctors were still concerned, and Carly very

nervously agreed to have a mammogram soon after

the birth. Thankfully, she was clear – the cancer hadn’t

come back. So the time had

come for Carly to resume her

treatment. But, she had other

ideas. ‘I wanted another baby!’

she explains.

‘I thought I might not get to

see Lydia grow up, so she would

need someone else.’

Just 12 months after Lydia

was born, Carly gave birth to

Rowan. It was not easy and,

after she went back on tamoxifen

and Zoladex, life didn’t get much

EHWWHU��μ7KH�¿UVW�\HDU�RI�5RZDQ¶V�

life is just a blur if I’m honest – all

the hormones, two babies – and

I knew how lucky I was but I

GH¿QLWHO\�GLGQ¶W�IHHO�YHU\�OXFN\�¶�

Today, two and a half years after Rowan’s birth,

Carly is 37 and has received the all-clear. She only

has to visit the hospital every 12 months. But after

all the hormone treatment, her body has entered the

early stages of the menopause. If she’d waited until now

to have the children, it would have been too late. ‘I look

back on it and I think, “was I a bit silly?” But I just knew

that I wanted children – I wanted that life,’ says Carly.

‘She’s been through so much,’ says Carly’s mum,

Pat. ‘And she does get a bit down, but I just have to say,

“Look what you’ve got now”.’

‘I know I’m the luckiest woman in the world,’ says

Carly. ‘But I’ve been through so much and I know how

important it is that more research is done for young

women like me. I don’t want my daughter, Lydia, to ever

have to worry about not being able to have children. Or

about getting to see her children grow up.’

I’VE BEEN

THROUGH

SO MUCH –

I KNOW HOW

IMPORTANT

DOING MORE

RESEARCH IS

FOR WOMEN

LIKE ME



EMMA FREEBORN:In February this year we lost two of our most inspiring supporters. Emma Freeborn and Kirste Bowman were both diagnosed with breast cancer in 2005, but this was not enough to stop either woman from continuing with their busy lives and raising money and awareness for Campaign

THEIR LEGACY LIVES ON

Emma (above) was diagnosed with HER2 positive

breast cancer when she was just 27 and she had a

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and won a Cosmopolitan�PDJD]LQH�DZDUG��DORQJ�ZLWK�

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(PPD��DQ�μLQVSLUDWLRQ¶��6KH�ZDV��DQG�ZLOO�FRQWLQXH�WR�EH��

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We remember

happy

Kirste with

husband John and

at Run to the Beat

ALWAYS AN INSPIRATION

inspiring

Emma was not

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what she needed


RUNNING ALL THE WAY

OLYMPIC TORCH

BURNS FOR KIRSTE


KIRSTE BOWMAN:

If you’ve been inspired by Kirste and

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YLVLW�EUHDVWFDQFHUFDPSDLJQ�RUJ

BE PART OF THE CURE

A QXPEHU�RI�RXU�%UHDVW�&DQFHU�&DPSDLJQ�

supporters were torchbearers in the 2012

Olympic Torch relay–and Kirste should have

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%RZPDQ�FDUULHG�WKH�WRUFK�RQ�KHU�EHKDOI��+H�

told Pink Science what it meant to him:

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enjoyed the experience!

A lEading light

-RKQ�OLJKWV�WKH�

‘cauldron’ in

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Chelmsford

“

”

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26 [ P I N K P I C K S ]


SPEND AND SAVE

There’s never been a better excuse to splash out at the shops. Watch out

for ‘pink picks’ like these and a contribution from your shopping will

help Breast Cancer Campaign to fund life-saving research

Pink Picks

BEJEWELLED

Buy this gorgeous rhodium-

plated pink crystal ribbon

pendant and bid.tv will

donate 99p to Campaign

£9.99, bid.tv

99p donation to Campaign

HAPPY SHOPPER

This bright pink bag

designed by Julien

Macdonald will brighten up

even the dullest of days

£2.50, asda.co.uk

80p donation to Tickled Pink

CUP OF LOVE

Pour yourself a truly heart-

warming drink in these pretty

mugs with love hearts

£2.50, call 01268 505 090

Ethos is donating £10,000 to

Campaign this year

SWEET DREAMS

Everything you need for a

matching bedroom – bid.tv

are selling this pretty-in-pink

bed set in a bag

£14.32, bid.tv

£1.43 donation to Campaign

WALK ON SUNSHINE

Multipacks of Walkers’

delicious SunBites have

gone all rosy for Tickled Pink

£1, asda.co.uk

PepsiCo will donate £85,000

to Tickled Pink

TOP BUY

Order your pink vest

and help us celebrate

10 years of fantastic

Damart support

£16-18, damart.co.uk

£4 donation to Campaign

GET JUICY

Satisfy your thirst with this

delicious English Apple juice

from Copella

£1, asda.co.uk

PepsiCo will donate £85,000

to Tickled Pink

Policy News

POWER UP

Charge your phone or

MP3 player on the go with

the genius Pink Pebble

Smartstick from Veho

From £20, amazon.co.uk


PINKIE PINK

Bring a touch of glamour to

this October’s wear it pink

and paint your ‘pinkie’ pink

with this nails inc. shade

£11, nailsinc.com


HIGH FASHION

This brooch by Zandra

Rhodes is as iconic and

glamorous as the lady who

designed it

£30, adele-marie.com

£3 donation to Tickled Pink

[ P I N K P I C K S ] 27


TIE IT UP

This cute lace bow jumper is

available from Asda, and

£1 from every sale will go

to Tickled Pink

£6, asda.co.uk

£1 donation to Tickled Pink

DRINK PINK

Grab a bottle of Lucozade’s

brand new pink

lemonade drink to support

Tickled Pink

£1.99, asda.co.uk


DEAR DIARY

Never miss a date

with this beautiful

leather-look personal

organiser from Filofax

��¿ORID[�FR�XN


ROSE-TINTED

Write, doodle or draw

with this gorgeous pink

gel pen with black ink

from Pentel

£2.99, pentel.co.uk


PINK PERFECTION

Buy this gorgeous London

Treasures Pink Crystal

Bracelet and bid.tv will

donate £1.49 to Campaign

£14.99, bid.tv

£1.49 donation to Campaign

COMFORT FOOD

Mrs Crimble’s are donating

an amazing £25,000 from

sales of their Cranberry

macaroons to Campaign

£1.69, mrscrimbles.com


SWEET CHARITY

Perfect with a cup of tea

– special pink packs of

Jaffa Cakes are supporting

Tickled Pink

£1, asda.co.uk


SWEET TOOTH

Indulge your sweet tooth

with this rich milk chocolate

to help raise money for

Andi’s Fund

£1.35, seedandbean.co.uk

13.5p donation to Campaign

FEELING ROSY

Shampoo and conditioner

from celebrity hairstylist

Andrew Barton

��RU��IRU�WZR��DVGD�FR�XN�

£6,000 total donation to

Tickled Pink

THINK PINK

Tell the whole world exactly

what you think about Think

Pink with this fun T-shirt

from Debenhams

£12, debenhams.com

£4 donation to Think Pink

BE PART OF

THE CURE

We’re grateful to all

the companies and

organisations who

support Breast

Cancer Campaign.

For more products

sold in aid of the

FKDULW\��RU�WR�¿QG�

out the details of

stockists near

you, please visit

our product pages

at breastcancer

campaign.org

IN THE PINK

9DQLVK�LV�MRLQLQJ�WKH�¿JKW�

against breast cancer and

supporting wear it pink

once again with a donation

of £250,000

£3-6, most supermarkets

28 [ L E T T E R S ]


YOUR POINT OF VIEWWe love it when you get in touch with your letters and questions, or to share your experiences. So here’s a pick of our favourites...

QWe had a great attendance

at our recent event and

managed to raise £2,000. It would

be great if one of your team could

come along and be presented

with the cheque in person?

Mr Bosworth, Kenilworth

A Thank you for your amazing

fundraising. We are always

keen to meet and personally thank

our supporters who are helping to

fund our groundbreaking research.

But we are only one small London-

EDVHG�RI¿FH�DQG�GR�QRW�KDYH�

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VWDII��:H�GR��KRZHYHU��KDYH�VRPH�

ZRQGHUIXO�YROXQWHHUV�ZKR�FDQ�IXO¿O�

this sort of role and who do support

our charity by attending cheque

presentations. We will always try to

¿QG�D�YROXQWHHU�LI�ZH�FDQ��

QI’m interested in running

the Bupa Virgin London

Marathon 2013 for your charity as

it is very closely linked with my

family. Why is there a minimum

sponsorship of £1,750 and what

happens if I don’t raise enough?

Lisa, Bournemouth

AWe set a minimum sponsorship

OHYHO�IRU�D�QXPEHU�RI�UHDVRQV��

)LUVWO\��ZH�KDYH�WR�EX\�RXU�SODFHV�

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WKLV�FRVW��:H�DOVR�SD\�WR�DGYHUWLVH�

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support and awareness as possible.

And, of course, Campaign relies

RQ�VLJQL¿FDQW�GRQDWLRQV�WR�IXQG�

research. We ask all runners to sign

a fundraising pledge and to accept

our terms and conditions to raise

the minimum amount. We are here

WR�SURYLGH�VXSSRUW��SURPRWLRQDO�

materials and sponsorship forms.

$QG�GRQ¶W�IRUJHW�WKDW�\RX�KDYH�D�

couple of months after the race has

¿QLVKHG�LQ�ZKLFK�WR�FROOHFW�WKH�UHVW�

of your sponsorship.

CHEQUE MATE

HOW CAN WE HELP?

WHY IS SPONSORSHIP SO HIGH?

Q My company is planning

to hold a fundraising

event in October during Breast

Cancer Action Month, and I’d

like to obtain an information

pack about workplace

fundraising to help with ideas?

Lisa, Runcorn Cheshire

A We’re delighted to hear that

you and your company are so

keen to support us by fundraising

in the workplace. At Campaign,

ZH�EHOLHYH�WKDW�HYHU\RQH�FDQ�

BE PART OF THE CURE. We’re

a unique community of scientists

and supporters dedicated

to pioneering breast cancer

research. October is a great

WLPH�WR�JHW�LQYROYHG��DQG�RQH�

of the best ways is by holding

a wear it pink day on October

26. This is Campaign’s biggest

IXQGUDLVLQJ�HYHQW�ZKHQ�SHRSOH�

wear pink at work, school or

home and make a donation to

Breast Cancer Campaign. Visit

wearitpink.co.uk to register.

)XQGUDLVLQJ�SDFNV�ZLOO�EH�DYDLODEOH�

from early September.

In July, we were thrilled to reach our

400,000th ‘like’ on Facebook. To

celebrate this milestone, we offered

WR�JLYH�DZD\�IUHH�SLQN�ULEERQ�HQDPHO�

pin badges to you, our supporters.

2YHU��RI�\RX�UHTXHVWHG�RXU�SLQ�

badge, and we know you’ll be

wearing them with pride.

A huge thank you to all of you who

FRQWULEXWH�WR�WKH�FRQYHUVDWLRQV�RQ�RXU�

social networks. They wouldn’t be

such a success without you, so

here’s to more ’likes’ in the future.

GET IN TOUCH

WRITE TO US AT:

Breast Cancer Campaign,

Clifton Centre, 110 Clifton Street,

London EC2A 4HT

CALL supporter care:

020 7749 4114

EMAIL US AT:

[email protected]

visit OUR WEBSITE:

breastcancercampaign.org/aboutus

TWEET US:

@BCCampaign

FACEBOOK AT:

facebook/breast

cancercampaign

FACEBOOK

MILESTONE

30 [ G A L L E RY ]


1

CHARITY

STARS

Taking part

You’ve been busy fundraising, and we’d like to say thank you

1 AET Swim School and Tamworth Life Saving Club swam

the length of the English Channel in their pool to raise

more than £1,700. 2 The Stowmarket and North Tyneside

regional groups walked Hadrian’s Wall, raising £1,000.

3�9LFFL�&ROH��7LQD�2OG¿HOG�DQG�$LPHH�&ROH�UDLVHG��

on their Snowdon challenge. 4 Marie McPherson trekked

Kilimanjaro, raising £5,000. 5 Noble Fuels staff walked

from Saltburn by the Sea to Whitby Abbey, raising almost

£1,600. 6 Lin Pelling’s annual Pink Tractor Road Run

raised £2,500. 7 Mike King’s team walked the Yorkshire

Three Peaks, raising over £6,000. 8 Nikki Elmer ran the

Severn Bridge to Wales and back, raising £300. Thank you!

2

3

4

5

6

7

8

26 OCT

2012

Breast Cancer Campaign is a charity registered by the Charity Commission for England and Wales (no.299758). wear it pink® is a registered trademark.

REQUEST YOUR FREE FUNDRAISING PACK TODAY AT:

wearitpink.co.uk 0800 107 3104

At work, at school

or even on a nigh t in, people

across the country will be coming

together to wear something pink in

the fight against breast cancer.

Hold a wear it pink day on

26 October and get ready to

be part of the cure.

pink science

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