1

anti-epileptic drugs

2

Photographs of some currently licensed brand and branded generic anti-epileptic drugs (AEDs) used to treat epilepsy in children, young people and adults in the UK.

AEDs are listed alphabetically by their generic name. Where no brand or branded generic version is available, a generic version is included. *Indicates where generic versions are also available.

Tablets and capsules are shown actual size. Colours may vary slightly depending on the device used to access this information.

For more about licensing and indications for use, see the British National Formulary (BNF) and the British National Formulary for Children (BNFC).

For more information about consistency of supply of AEDs, see page 35.

3

Acetazolamide* – acetazolamide

Tablets 250mg

1.1cm

4

Briviact – Briviracetam

Tablets 100mg

75mg

50mg

25mg

10mg

1.5cm

5

Carbamazepine* – Tegretol/Tegretol Prolonged Release

Prolonged release 400mg

200mg

Tablets 400mg

200mg

100mg

1.7cm

6

Carbamazepine* – Carbagen/Carbagen prolonged release

Tablets 400mg

200mg

200mg

1.3cm

Prolonged release tablets 400mg

7

Clobazam* – Frisium

Tablets 10mg

0.7cm

8

Clobazam* – Tapclob

Suspension

5mg/5ml 10mg/5ml

9

Eslicarbazepine acetate – Zebinix

Tablets 800mg

200mg

1.9cm

10

Ethosuximide* – ethosuximide

Capsules 250mg

1.5cm

11

Gabapentin* – Neurontin

Capsules 400mg*

300mg*

100mg*

Tablets 800mg*

600mg*

2.1cm

12

Lacosamide – Vimpat

Tablets 200mg

150mg

100mg

50mg

1.6cm

13

Lamotrigine* – Lamictal

Dispersible Tablets

100mg

25mg

5mg

2mg

Tablets200mg

100mg

50mg

25mg

1cm

14

Levetiracetam* – Keppra

Tablets 1000mg

750mg

500mg

250mg

1.9cm

15

500mg

250mg

Levetiracetam* – Desitrend

Note – sachets not to scale

Granule – 2mm

1000mg

Sachets/granules

16

Oxcarbazepine* – Trileptal

Tablets 600mg

300mg

150mg

1.9cm

17

Perampanel – Fycompa

Tablets

12mg

10mg

8mg

4mg

6mg

2mg

0.8cm

18

Phenobarbital* – phenobarbital

Tablets 60mg

30mg

15mg

0.7cm

19

Phenytoin* – Epanutin

Tablets Chewable Infatabs

50mg

1cm

20

Phenytoin* – Phenytoin Sodium Flynn

Capsules 300mg

25mg

100mg

50mg

1.9cm

21

Piracetam* – Nootropil

Tablets 1200mg

800mg

2.1cm

22

Pregabalin* – Lyrica

Capsules 300mg

225mg

200mg

150mg

100mg

75mg

50mg

25mg

2cm

23

Primidone* – primidone

Tablets 250mg

50mg

0.9cm

24

Rufinamide – Inovelon

Tablets400mg

200mg

100mg

1.8cm

25

Sodium Valproate* – Epilim/Epilim Chrono

Note – sachets not to scale

Sachets/granules

750mg

500mg

250mg

100mg

50mg

Crushable Tablets 100mg

200mg

Tablets500mg

Epilim Chrono Tablets

500mg

1000mg

300mg

Granule < 1mm

200mg

1.7cm

26

Sodium Valproate* – Episenta

Sachets/granules

1000mg

500mg

Note – sachets not to scale

Granule – 2mm

Capsules 300mg

150mg

0.9cm

27

Sodium Valproate* – Epival

Tablets 500mg

300mg

300mg

1.8cm

28

Stiripentol – Diacomit

Sachets/powder 500mg

250mg

250mg

Capsules 500mg

Note – sachets not to scale

1.8cm

29

Tiagabine – Gabitril

Tablets 15mg

10mg

5mg

1.3cm

30

Topiramate* – Topamax

Capsules 50mg

25mg

15mg

Tablets 200mg

100mg

50mg

25mg

2cm

31

Valproic acid – Convulex

300mg

150mg

Capsules 500mg

2.1cm

32

Vigabatrin – Sabril

Tablets 500mg

Tablets/granules

Note – sachet not to scale

Granule > 1mm

1.7cm

33

Zonisamide* – Zonegran

Capsules 100mg

50mg

25mg

1.9cm

34

further information Epilepsy Society information

Medication for epilepsy booklet Epilepsy for pharmacists factsheet Medicines use review – epilepsy consultation brief other organisations

NICE – Epilepsies: diagnosis and managementnice.org.uk/guidance/cg137 MHRA – Valproate use by women and girls gov.uk/guidance/valproate-use-by-women-and-girls

35

Every effort is made to ensure that all information is correct at the time of publishing. This information is not intended to be a substitute for medical guidance. Epilepsy Society is not responsible for any actions taken as a result of using this information. None of this information should be reproduced, in full or in part, without written permission from Epilepsy Society.

consistency of supply

“Consistent supply… of a particular manufacturer’s AED preparation is recommended, unless the prescriber, in consultation… considers that this is not a concern.”

The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care.

National Institute for Health and Clinical Excellence, 2012.

For more about consistency of supply visit:epilepsysociety.org.uk/generic-and-branded-anti-epileptic-drugs

36

Epilepsy SocietyChesham Lane, Chalfont St. Peter, Bucks SL9 0RJ01494 601 300

©Epilepsy Society August 2018Registered charity no. 206186

epilepsysociety.org.uk

The production of this booklet has been made possible through unrestricted educational grants from Desitin Pharma Ltd and UCB Pharma Ltd.