physiology - mcq bank[1]
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1.Thecarotidbodies:a)havealowbloodflowpergram
oftissueb)containbaroreceptorsc)respondtochangesinpHd)respond
tosmallchangesinPaO
2e)arelocatedonthe
externalcarotidarteries
2.Thefollowingareexamplesofactivetransport:
a)sodiumextrusion
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fromcellsb)waterreabsorptionfromthe
proximalconvolutedtubulec)potassiumexcretioninthedistalconvolutedtubuled)
glucoseabsorptionfromthegutc)waterreabsorptionintheloopofHenle
3.Growthhormoneandinsulinhaveoppositeeffectson:a)carbohydrateuptakebymuscleb)catabolismoffatc)synthesisoffatd)
synthesisofprotein
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e)somaticgrowth
4.Stimulation
ofthetenthcranialnervecauses:a)slowingofA-Vconductionb)
constrictionofcoronaryvesselsc)increasedsecretionofgastricacidd)miosise)
relaxationofthepylorus
5.Anincreaseinsympatheticstimulationtotheheartcauses:a)afallindiastolictimeb)afall
indP/dtc)
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anincreaseinstrokevolumed)dilation
ofthecoronaryvasculaturee)anincreaseinmyocardialoxygenconsumption
6.Ifoxygenisaddedtoinspiredairtoincreaseitspartial
pressurefrom20kPa(150mmHg)to60kPa(450mmHg):a)dissolvedoxygenwillincreaseapproximatelythree-foldb)theoxygencontentoftheblood
willincreaseapproximately
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three-foldc)thePaNwillremainthesame
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d)thePaOwill
increaseapproximatelythree-fold
2e)hypercarbiawillbeprevented
7.Pulmonaryvascularresistanceisincreasedby:a)serotoninb)hypocarbiac)
hypoxiad)afallinpHe)adrenaline
8.Onchangingfromtheuprighttothesupineposition:a)baroreceptoractivitydecreasesb)
legveinpressure
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isreducedc)thebloodvolumein
thepulmonarycirculationfallsd)strokevolumeincreasese)reninactivityincreases
9.Thefallinurineoutputassociatedwithmajortraumamay
becausedby:a)haemorrhageb)ariseinantidiuretichormoneactivityc)afallinaldosteroneactivityd)anincreaseinthelevelof
circulatingcatecholaminese)
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ariseincorticosteroidoutput
10.Inthefoetalcirculationbeforebirth:a)thePOishigherin
theductusvenosusthanintheductusarteriosus
2b)blood
cangofromtherightatriumtotheaortawithoutpassingthroughtheleftatriumandventriclec)thePOintheaorticarchishigher
thaninthe
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descendingaorta
2d)blood
flowingthroughtheforamenovalecomesprincipallyfromthesuperiorvenacava
e)bloodpassesthroughtheductusarteriosusbecauseofthehighpulmonaryvascular
resistance
11.Inthecentralvenouspressurewaveform:a)theawaveoccursafterventricularsystoleb)thevwaveiscausedby
atrialcontractionc)
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theawaveisabsentinatrial
fibrillationd)theawavecorrespondswithclosureoftheaorticvalve
e)thevwaveoccursduringdiastole
12.Reninactivityis
increasedby:a)anincreaseincirculatingadrenalineb)hypotensionc)increasedsodiumingestiond)anincreaseinaldosteroneoutpute)hypovolaemia
13.
Acuteantagonismof
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betaadrenergicreceptorscauses:a)hyperglycaemiab)
peripheralvasodilatationc)suppressionofuterinecontractility
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d)pupillarydilatation
e)areductionincardiacoutput
14.Unilateraltransectionof
dorsalnerverootsC3-T2produces:a)motorparalysisb)lossofsensationc)
lossofreflexesd)lossofsympatheticandsudomotortonee)hypotonia
15.Therateofgastricemptyingis:a)delayedbyfat
intheduodenum
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b)delayedbysecretinc)delayedby
fatintheoesophagusd)enhancedbyalcohole)independentofvolume
andtypeoffoodingested
16.Anincreaseinaldosteroneproduction
occursinresponseto:a)ingestionofsodiumchlorideb)anincreaseinbloodvolumec)anincreasedintakeofpotassiumd)angiotensinIIe)
trauma
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17.Cerebrospinalfluid:a)isthemain
sourceofbrainnutritionb)ismainlyproducedbyactivesecretionfrom
thechoroidplexusc)containsvirtuallynoglucosed)pHchangesrapidlyin
responsetochangesinplasmapHe)pressureincreaseswithjugularvenousobstruction
18.Carbonicanhydraseisfoundathighconcentrationin:a)
plasmab)red
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bloodcellsc)renaltubularcellsd)
gastricparietalcellse)cardiacmusclecells
19.TheHb-oxygen
dissociationcurveshiftstotherightin:a)acutehypoxiab)storedblood
c)metabolicacidosisd)respiratoryalkalosise)hypothermia
20.Thefunctionalresidualcapacity:a)isincreasedintheobeseb)isapproximately10%
higherinmen
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thaninwomenc)fallswithgeneral
anaesthesiad)increasesonchangingfromthesupinetothestandingposition
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e)fallswithincreasingageANSWERS1.FFTFF2.TFTTF3.TTTFF4.TFTFT5.TFTTT6.TFFTF7.TFTTF8.FTFTF9.TTFTT10.TTTFT11.FFTFT12.TTFFT13FFFFT14.FTTFF15.TTFFF16.FFTTT17.FTFFT18.FTTTF19.FFTFF20.FTTTTVisitwww.anaesthesiauk.comformorearticlesandpracticequestio
ns!
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Printthispage!PhysiologyMCQBank1Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!1.
Incalculatingtheshuntfraction,thefollowingneedtobemeasuredor
estimated:a)mixedvenousoxygencontentb)pulmonaryend-capillaryoxygencontentc)arterial
oxygencontentd)alveolarpartialpressureofoxygene)haemoglobinconcentration
2.Pulsepressureincreaseswithanincreasein:a)strokevolumeb)
leftventricularend-diastolic
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volumec)arterialpartialpressureofoxygen
d)systemicvascularresistancee)bloodviscosity
3.Acuteuntreated
haemorrhagicshockinapatientwillleadto:a)anincreaseinphysiological
dead-spaceb)anincreaseinthearterio-venousPCOdifference
2c)afallinthepulmonaryvascularvolumed)anincreaseinantidiuretichormone
secretione)an
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increaseinplasmabicarbonateconcentration
4.Anincreaseinaldosteronesecretionfollows:a)asodiumchlorideload
b)ariseinbloodvolumec)anincreaseinoralpotassiumabsorption
d)traumac)anincreaseinproductionofangiotensinII
5.Stimulationofalpha-adrenergicreceptorswillcause:a)vasoconstrictionofthecoronaryarteries
b)increasedtone
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inthebladderneckmusclec)increased
plateletaggregationd)lipolysise)bronchodilation
ANSWERS
1.TTTTT
2.TTFFF3.TFTTF4.FFTTT5.TTTFF
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Printthispage!PhysiologyMCQBank2Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!6.
Inthenormaladultheart:a)mitralvalveclosureoccursbeforetricuspid
valveclosureb)pulmonaryvalveclosureoccursbeforeaorticvalveclosurec)there
isisometriccontractionoftheleftventricleaftertheaorticvalveopensd)atrialcontractionisofmoreimportancetoventricularfillingiftheheart
rateincreasese)
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theaorticvalvecuspsareimmobileduring
ventricularfilling
7.Resistancetolaminarflowinavessel
is:a)proportionaltowallthicknessb)inverselyproportionaltothefourthpower
oftheradiusc)proportionaltolengthd)independentofhaematocrite)proportionaltothepressuredrop
8.Autoregulatorymechanismsusedinhypovolaemia
include:a)an
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increaseinprecapillarysphinctertoneb)an
increaseincapillaryhydrostaticpressurec)adecreaseinbaroreceptoractivityd)
stimulationofthejuxtaglomerularapparatuse)anincreaseinangiotensinII
9.Myocardialcontractilityisincreasedby:a)catecholaminesb)anincreaseinheartratec)anincreaseinfibrelengthd)anincreaseinparasympathetic
nervoussystemactivity
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e)calciumions
10.The
carotidsinuses:a)havestretchreceptorsintheirwallsb)giveafferent
impulsesviatheglossopharyngealnervec)stimulatetherespiratorycentred)containchemoreceptors
e)stimulatethevasomotorcentre
ANSWERS
6.TFFTT7.FTTFF8.TTTTT9.TTTFT10.TTFFT
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Printthispage!PhysiologyMCQBank3Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!11.
Thefollowingcauseadecreaseinthearterialpartialpressureofoxygen:
a)anaemiab)carbonmonoxidec)hyperventilationd)ariseinphysiologicaldead-space
e)oldage
12.Ironabsorptionisdependenton:a)totalbodyvitaminCb)HClinthestomachc)anintactcolonic
mucosad)total
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bodyirone)erythropoietinlevelsinthe
blood
13.Ifanormalpersonhyperventilatesfor2hours
toanarterialPCOof42kPa:
a)thecerebralblood
flowdecreasesb)thestandardbicarbonatedecreasesc)theHb-oxygendissociationcurveshiftstotheleftd)theionisedcalciumconcentrationdecreasese)theplasma
bicarbonateincreases
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14.Hypoglycaemiamayresultfrom:a)
excessiveinsulinsecretionb)alpha-adrenergicstimulationc)beta-adrenergicstimulationd)glucagonsecretion
e)hypothermia
15.Ingestedlipid:a)isimportantinprostaglandinsynthesis
b)increasesinthefaeceswithadecreaseinbilesecretionc)isabsorbedviatheintestinallymphaticsd)ismainlyintheformof
triglyceridese)can
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beusedasasourceofATP
production
ANSWERS
11.FFFFT12.FTFTF13.TFTTF14.TFTFF15.TTTTT
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Printthispage!PhysiologyMCQBank4Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!16.
Thefollowingmaybefoundinnormaladultvenousblood:a)3%
carboxyhaemoglobinb)5%methaemoglobinc)70%oxyhaemoglobind)2%freehaemoglobine)2%
fetalhaemoglobin
17.Innormalhumanlungs:a)alowPOproducespulmonaryvasodilatation
2b)beta-2agonistscausebronchoconstrictionc)pulmonary
vascularresistanceis
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increasedbyserotonind)pulmonaryvascularresistance
isdecreasedbyhistaminee)pulmonaryvascularresistanceisdecreasedbynoradrenaline
18.Thenormalresponsetosurgeryincludes:a)adecreasein
urinevolumeb)adecreaseintheurinaryexcretionofsodiumc)adecreaseinplasmacortisolleveld)anincreaseintheurinaryexcretion
ofnitrogene)
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anincreaseintheurinaryexcretionof
potassium
19.Capillarypermeabilityisincreasedby:a)bradykininb)
adrenalinec)calciumd)vasopressinc)histamine
20.Expectedchangesin
apatientwithaphaeochromocytomainclude:a)adecreasedhaematocritb)adecreasedtotalbloodvolumec)adecreasedserumsodiumconcentrationd)anabnormal
glucosetolerancetest
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e)areducedmetabolicrate
ANSWERS
16.TFTFF17.FFTFF18.TTFTT19.TFFFT20.FTFTF
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Printthispage!PhysiologyMCQBank5Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!1.
Theliver:a)receivesmostofitsoxygensupplyfromtheportal
veinb)hasitshighestoxygentensionatthecentreofalobule
c)producesheparind)hasanormalportalvenouspressureofgreaterthan20mmHge)receivesapproximately25%ofthecardiacoutput
2.Skeletalmuscle
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bloodflow:a)increaseswithnoradrenalineb)
receives50%ofthecardiacoutputatrestc)mayceaseduring
isometriccontractiond)increaseswithrhythmiccontractione)increaseswithadrenaline
3.Inthermoregulation:a)respiratoryheatlossisinsignificantundernormalconditionsb)brownfatisanimportantsourceofheatproductioninneonatesc)
shiveringisdue
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toimpulsesconductedviaautonomicefferentsd)
peripheralvasoconstrictionincreasesheatproductione)sweatingismediatedbysympatheticcholinergic
neurones
4.Adrenaline:a)issynthesizedbydemethylationofnoradrenalineb)
increasescoronarybloodflowc)increasesfreefattyacidsinthebloodd)mobilizesglycogenstoresfromthelivere)ismetabolizedintheplasma
bymonoamineoxidase
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5.Glucagon:a)isa
positiveinotropeb)isproducedbythebetacellsofthepancreas
c)stimulatesproductionoffreefattyacidsinthebloodd)releaseis
increasedinstarvatione)stimulatesglycogensynthesis
ANSWERS
1.TFTFT2.FFTTT3.TTFFT(fundamentalsofanaesthesia,2ndeditionpage446)4.FTTTF5.TFTTF
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Surfactant:a)isamucopolypeptideb)causesadecreaseinsurfacetension
c)resultsinthesamesurfacetensionfordifferentsizedalveolid)causes
anincreaseincompliancee)productionisreducedafteraprolongedreductioninpulmonarybloodflow
7.Sinusarrhythmia:a)producesalengthening
oftheP-R
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intervalb)producesalengtheningofthe
R-Rintervalc)ismaximalwithbreathholdingd)ismoremarked
duringexercisee)ismoremarkedin70yearoldsthanin20
yearolds
8.Apressure-volumecurvecanbeusedformeasuring:a)theworkofbreathingb)functionalresidualcapacityc)anatomicaldead
spaced)compliance
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e)respiratoryquotient
9.The
absoluterefractoryperiodforcardiacmuscleis:a)aslongasthe
entireactionpotentialb)theperiodwhennofurtheractionpotentialcanbe
stimulatedc)twicethelengthoftheS-Tintervald)aslongasthemechanicalcontractione)shorterforpacemakertissuethanfornormalcardiac
muscle
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10.Inayoungnormaladult:a)
theglomerularfiltrationrateisapproximately125ml/minb)the24hour
urinecreatininecontentisapproximately800mgc)urinespecificgravityisalways
lessthan1000d)renalbloodflowisapproximately20%ofcardiacoutpute)over50%ofwaterreabsorptionfromtheglomerularfiltrateoccursin
thecollectingducts
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ANSWERS
6.FTFTT7.FTFFF
8.TFFTF9.FTFFT10.TFFTF
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Totalplasmacalcium:a)increaseswithphosphateb)increaseswitharise
inalbumin,c)changesitsdegreeofionisationwithpHchangesd)is
decreasedinosteoporosise)isaffectedbyvitaminD
12.Thereisincreasedintestinalmotilitywith:a)increasedintraluminalpressureb)anticholinesterasedrugs
c)sympatheticblock
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toT4d)stimulationofthesplanchnic
nervese)increasedcirculatingadrenaline
13.Ahealthyadultbreathing
anFIOof0.1will:2
a)haveadecreasedcardiacoutput
b)haveanormalPaO
2c)haveachangedalveolarPCO
2d)haveanunchangedrespiratoryratee)initiallyhavea
fallinpH
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14.Acetylcholineisaneurotransmitter
at:a)sweatglandsb)theadrenalmedullac)theparotidgland
d)parasympatheticgangliae)theneuromuscularjunction
15.Insulin:a)has
thesameeffectonbloodsugarasgrowthhormoneb)inhibitsentryofpotassiumintocellsc)facilitatesproteinanabolismd)increasesdepositionoffats
e)secretionis
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affectedbycatecholamines
ANSWERS
11.FTTFT12.TTTFF13.FFTFF14.TTTTT15.FFTTT
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Inanormalrestingsubject,abradycardiawouldbeexpectedfollowing:a)
anincreaseincarotidsinuspressureb)anincreaseinrightatrialpressure
c)applicationofpressuretotheeyeballd)thereleaseofaValsalvamanoevree)inspiration
17.Thevelocityofconductionofa
nerveactionpotential:
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a)isinverselyrelatedtothecross-sectional
areaoftheaxonb)isfasterinamyelinatedfibrethan
inanunmyelinatedonec)isdecreasedbycoolingthenerved)can
exceed100m/sinhumanse)ishighestinpre-ganglionicautonomicfibres
18.Theplacenta:a)transportsglucosefrommaternaltofoetalblood
byfacilitateddiffusion
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b)cansynthesizeglycogenc)activelytransports
oxygenfrommaternaltofoetalbloodd)allowsproteinmoleculestopass
frommaternaltofoetalbloodbypinocytosise)secretesoestradiol
19.
Oxytocin:a)stimulatesproductionofmilkb)stimulatesejectionofmilkc)releaseisstimulatedbydilatationofthecervixd)issynthesizedinthe
anteriorpituitarye)
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producesmorepowerfuluterinecontractioninthe
presenceofprogesterone
20.Aldosterone:a)productionincreaseswitha
fallinplasmaosmolalityb)productiondecreaseswithafallinbloodvolume
c)productiondecreaseswithariseinplasmareninleveld)increasesurinarypotassiumexcretione)maybeproducedbytumoursoftheadrenalcortex
ANSWERS
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16.TFTTF17.FTTTF18.TFFFT19.FTTFF20.FFFTT
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Printthispage!PhysiologyMCQBank9Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!1.
Adrenalinea)issecretedbytheadrenalcortexb)decreasessystemicvascular
resistanceatlowdosesc)decreasespulmonaryvascularresistanced)constrictsthepupil
e)actsonlyatbeta-1receptors
2.Atypicalmammalianmotorneurone:a)innervatesonlyoneskeletalmusclecellb)ismyelinatedc)
hasitscell
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bodyintheventral(anterior)hornof
thespinalcordd)mightreceiveaninputdirectlyfromGroupIa
afferentfibresinthespinalcorde)wouldbestimulatedbyapplicationof
glycinetoitscellbody
3.Thevagusnerve:a)haslittledirecteffectonthestrengthofventricularcontractionb)containsafferent
andefferentfibres
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c)containsparasympatheticpost-ganglionicfibresd)contains
fibreswhichregulategastricacidsecretione)hasaroleinbladder
emptying
4.Vitalcapacity:a)isthevolumeofairexpired
fromfullinspirationtofullexpirationb)increasesgraduallywithageinadultsc)isgreaterinmenthaninwomenofsimilarageand
heightd)is
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equaltothesumoftheinspiratory
andexpiratoryreservevolumese)maybemeasuredbyspirometry
5.Hyperventilationinanormalsubjectfor24hourswillproducea:a)
fallinPaCO
2b)riseinPaCO
2c)riseinionisedcalciumd)fallincerebrospinalfluidbicarbonatee)risein
plasmabicarbonate
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ANSWERS
1.FTTFF2.FTTTF3.TTFTF
4.TFTFT5.TFFFF
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6.Theblood-brainbarrier:a)resultsincertainmoleculesintheblood
takinglongertoequilibratewithtissuefluidinthebrainthanwithtissue
fluidelsewhereb)permitsCOtopassfreely
2c)ismorepermeabletowater-solublesubstancesthanfat-solublesubstancesd)ismorepermeablein
neonatesthanin
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adultse)isreadilycrossedbydopamine
7.Areflexaction:a)maybecarriedoutby
skeletal,smoothorcardiacmuscleorbyglandsb)isnotinfluencedby
highercentresinthebrainc)resultsfromactivityinatleasttwocentralnervoussynapsesinseriesd)mayinvolvesimultaneouscontractionofsome
skeletalmusclesand
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relaxationofotherse)canbemonosynaptic
orpolysynaptic
8.Platelets:a)areproducedinthebone
marrowb)increaseinnumberaftertissuedamagec)haveasmallnucleus
d)altertheirshapewhentheymakecontactwithcollagene)areactivatedbyADPandthrombin
9.Thepressure:a)dropacross
themajorveins
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issimilartothatacrossthemajor
arteriesb)dropacrossthehepaticportalbedissimilartothat
acrossthesplenicvascularbedc)inthehepaticportalveinishigher
thanthatintheinferiorvenacavad)dropacrossthevascularbedinthefootisgreaterwhenstandingthanwhenlyingdowne)
dropacrossthe
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pulmonarycirculationisthesameasacross
thesystemiccirculation
10.Athletesdifferfromnormalindividualsin
having:a)ahigherrestingcardiacoutputb)ahigherrestingheartrate
c)adecreasedmusclemassd)ahighermaximumoxygenconsumptione)increasedmuscularefficiencyathighbloodlactatelevels
ANSWERS
6.TTFTF7.TFFTT8.TTFTT
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9.FFTFF10.FFFTT
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1.Stimulationoftheparasympatheticnervoussystem:a)increasestheheartrate
b)decreasestherateofgastricemptyingc)dilatesthepupild)causes
vasoconstrictione)causescontractionofthedetrusormuscleinthebladder
2.Pregnancyattermisassociatedwitha:a)20%decreasein
redcellmass
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b)riseincardiacoutputc)fall
inPaCO
2d)fallinhaematocrite)lowprotein-boundiodine
3.TheP5Ois:a)theoxygensaturationwhenthearterial
partialpressureofoxygenis50mmHgb)thearterialoxygentensionwhenhaemoglobinis50%saturatedc)anindicatorofthepositionofthe
oxygendissociationcurve
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d)raisedinfoetalbloode)lowered
inchronicanaemia
4.Inahealthyadulthumanheart
the:a)leftventricularend-systolicvolumeisapproximately30mlb)firstheart
soundcoincideswiththeonsetofventricularsystolec)strokevolumeisapproximately70mld)leftventricularend-diastolicpressureisabout50mmHge)
secondheartsound
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iscausedbyclosureoftheaortic
andpulmonaryvalves
5.Renin:a)isreleasedfromgranules
inthejuxtaglomerularcellsoftheafferentarterioleb)levelsintheblood
increaseinresponsetoafallinplasmasodiumconcentrationc)levelsintheblooddecreasewhenrenalperfusionisdecreasedd)releaseisenhanced
byangiotensinII
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e)releaseisinhibitedbyantidiuretichormone
ANSWERS
1.FFFFT2.FTTTF3.FTTFF4.TTTFT5.TTFFT
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Printthispage!PhysiologyMCQBank13Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!
1.Thefollowingaresecretedfromtheadrenalcortex:a)testosteroneb)
aldosteronec)angiotensind)noradrenalinee)deoxycorticosterone
2.Aldosterone:a)secretion
increasesinresponsetoafallinbloodvolumeb)isapolypeptidec)producesanincreaseinrenalarterialpressured)producesafall
inurinevolume
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e)increasesthereabsorptionofsodium
3.Cerebrospinalfluid:a)isactivelysecretedbythechoroidplexus
b)isthemajornutritionsourceofthebrainc)hasthesame
pHasarterialbloodd)containsvirtuallynoglucosee)hasahigherchloridelevelthanplasma
4.Redbloodcellproduction:a)
increasesduringacclimatisation
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toaltitudeb)canoccurinthe
spleenc)isdependentonnormalgastricsecretoryactivityd)isstimulated
byhypercarbiae)isdependentonervthropoietin
5.Bile:a)salts
contributetothesolubilityofcholesterolinthebileb)containsbilirubinmainlyintheunconjugatedformc)contributesmorethanpancreaticsecretiontothe
neutralisationofacid
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fromthestomachd)becomesmorealkaline
followingconcentrationinthegallbladdere)isproducedatarate
ofapproximately2000ml/day
ANSWERS
1.FTFFT2.TFTFT3.TFFFT4.TTTFT
5.TFFFF
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Printthispage!PhysiologyMCQBank14Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!
1.Carbonicanhydraseplaysaroleinthe:a)productionofHCl
bytheparietalcellsofthestomachb)secretionofhydrogenionsfrom
thefluidintherenaltubulesc)passageofCOfromthepulmonarycapillariestothealveoli
2d)secretionofbicarbonatebythe
pancrease)production
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ofredbloodcells
2.
Inapatientwithseverehypovolaemia,the:a)physiologicaldead-spaceincreasesb)
arterio-venousoxygendifferencedecreasesc)alveolar-arterialoxygendifferenceincreasesd)minutevolumeincreases
e)arterialPCOincreases
2
3.ThegroupAantigen:a)ispresentontheredcellsofagroupApatient
b)mayoccur
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inthesalivaofagroupA
patientc)istransmittedasanautosomalrecessivecharacteristicd)ismore
commonthanthegroupBantigene)isthemostcommoncauseof
haemolyticdiseaseofthenewborn
4.Theactionofnoradrenalinemaybeterminatedby:a)monoamineoxidaseinthenerveterminalb)catechol-O-methyltransferasein
theliverc)
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catechol-O-methyltransferaseinthenerveterminald)dopa
decarboxylaseinthenerveterminale)neuronalreuptake
5.An
increaseinthe2.3-DPGconcentrationinredbloodcellsoccursin:a)anaemia
b)acclimatisationtoaltitudec)storedbloodd)trainedathletese)cyanoticheartdisease
ANSWERS
1.TTFFF2.TFTTF3.TTFTF4.TTFFT5.TTFFT
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Printthispage!PhysiologyMCQBank15Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!
1.Innormalcerebrospinalfluid,the:a)chlorideconcentrationishigherthan
inbloodb)glucoseconcentrationisthesameasinplasmac)PCOis
higherthaninmixedvenousblood
2d)pHisthesameasinarterialbloode)bicarbonateconcentrationisthesameas
inarterialblood
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2.Whenbreathingoutagainst
aclosedglottis,the:a)intratrachealpressurerisesb)heartrateslows
transientlyc)rightventricularoutputincreasesd)leftventricularoutputhasasustained
increasee)systolicarterialpressurefallsthenrises
3.Changingpositionfromstandingtosupine:a)increasesstrokevolumeb)increasesbaroreceptoractivity
c)increasesthe
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pulmonarybloodvolumed)decreaseslegvein
pressuree)decreasestheheartrate
4.Vagalstimulationproduces:
a)afallinheartrateb)anincreaseinatrialcontractilityc)
anincreaseinventricularcontractilityd)slowingofA-Vconductione)afallinstrokevolume
5.Thefollowingarerepresentativeofmyocardial
afterload:a)mean
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aorticpressureb)meanpulmonaryarterypressure
c)leftventricularend-diastolicvolumed)leftventricularend-diastolicpressuree)the
rateofriseofleftventricularpressure
ANSWERS
1.TFTFF
2.TTFFF3.TTTTT4.TFFTT5.TTFFF
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Printthispage!PhysiologyMCQBank161.Onascendingtoanaltitudeof6000m,changesinclude:
a)anincreaseinminutevolumeb)aninitialincreaseinplasmapHc)ariseinurinepHd)afallinarterialPO2e)anincreaseincerebralbloodflow2.Transferrinis:a)involvedinironuptakebythegutmucosab)involvedinirontransportacrossthegutmucosac)involvedinirontransporttomuscled)involvedinirontransporttostoragesitese)normallyonly35%saturatedwithiron3.Breathing100%oxygenatatmosphericpressureforaprolongedperiodcauses:a)retrosternalpainb)dizzinessc)auditorydisturbancesd)convulsionse)atelectasis4.Thefollowingtransfusionswillleadtoagglutination:5.Chemoreceptorsinthearterialsystem:a)haveahigherrateofoxygenconsumptionpergramthanbraintissueb)respondtochangesinoxygentensionandnotcontentc)respondtochangesinpHd)conductafferentinformationviatheglossopharyngealandvagusnervese)arefoundinthecarotidsinusANSWERS1.TTTTF2.FFTTT3.
TFFFT4.TTFFT5.FTTTFDonorRecipienta)BOb)ABAc)BABd)OABe)ABOVisitwww.anaesthesiauk.comformorearticlesandpracticequestions!
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Printthispage!PhysiologyMCQBank17Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!
1.Inthehealthyheart,anincreaseinstrokevolumeisseen
withanincreasein:a)dP/dTb)aorticsystolicpressurec)leftventricular
end-diastolicvolumed)leftventricularend-systolicpressuree)heartrate
2.Thea-waveofthecentralvenouspressurewaveform:a)iscausedby
atrialcontractionb)
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isnotseeninatrialfibrillationc)
iscausedbyatrialfillingduringventricularcontractiond)decreaseswithinspiration
e)isfollowedbythev-wave
3.Intheelectrocardiogram,the:
a)P-RintervalisequivalenttotheA-Vnodalconductiontimeb)T-waveisequivalenttoventricularrepolarisationc)Q-Tintervalisequivalenttothe
durationofventricular
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contractiond)U-waverepresentssinoatrialnoderepolarisation
e)durationofanormalP-waveis0.2seconds
4.
Ptosisresultsfrom:a)parasympatheticblockb)sympatheticblockc)facialnerveblock
d)trigeminalnerveblocke)oculomotornerveblock
5.Thefollowingareprecursorsofadrenaline:a)tyrosineb)phenylalaninec)noradrenalined)dopamine
e)isoprenaline
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ANSWERS
1.TFTFF2.TTFFF3.TTTFF
4.FTTFT5.TTTTF
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Printthispage!PhysiologyMCQBank18Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!
1.Thefollowingleadtoanincreaseininsulinsecretion:a)glucagon
b)adrenalinec)growthhormoned)starvatione)majortrauma
2.
Adenylcyclase:a)increasestheconversionofATPtocyclicAMPb)iscloselylinkedtoalpha-andbeta-adrenergicreceptorsc)isinhibitedbyaminophyllined)
releaseistriggered
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bycyclicAMPe)actsata
mitochondriallevel
3.Surfactant:a)containsphospholipidsb)preventsoedema
formationinthealveolarwallc)reducessurfacetensionbyapproximately30%d)
producesamonomolecularlayere)stabilisesthesizeofanalveolus
4.Theoxyhaemoglobindissociationcurveisshiftedtotheleftby:a)
anincreasein
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arterialPCO
2b)acidosisc)
chronicanaemiad)carbonmonoxidee)afallintemperature
5.Intheadult,growthhormonestimulates:a)glucoseuptakeintocellsb)
calciumabsorptionfromthegutc)proteinsynthesisd)fatsynthesise)bonegrowth
ANSWERS
1.TFTFT2.TTFFF3.TTFFT4.FFFTT5.FFTFT
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