pharmaceutical compounding individualized patient care
TRANSCRIPT
Pharmaceutical CompoundingIndividualized Patient Care
Outline
I. IntroductionII. Who governs compoundingIII. Expected Growth and the Future
of CompoundingIV. Importance of Quality StandardsV. How I can help you
I. Introduction
Compounding
The preparation, mixing, assembling, altering, packaging, and labeling of a drug, drug-delivery device or device in accordance with a licensed practitioner’s prescription, medication order, or initiative based on the practitioner/patient/pharmacist/compounderrelationship in the course of professional practice
Compounded Lollipops
Role of the Compounding Pharmacist
• “Individualizing Drug Therapy”
History of Pharmacy Compoundingin the U.S.
• In the past, Compounding Was Pharmacy• 1900s gave way to commercially prepared
pharmaceuticals• Many strengths/dosage forms available• Economics changed all that• Limited strengths/dosage forms• “One Size Fits All” approach
Types of Compounding Pharmacies
• Independent Community Pharmacies• Chain Pharmacies• Hospital Pharmacies• Mail-Order Pharmacies• Compounding Only Pharmacies
– Independent (Human and Veterinary)– Specialty (Home Healthcare, Hospital Contract, etc.)
• Nuclear Pharmacies
Extent of Compounding in the U.S.
• More than 70% of pharmacies report they do some compounding(NCPA)
• Virtually all hospitals do compounding• All government hospitals compound• Even chain stores have compounding centers
Reasons for the Growth of Pharmacy Compounding
• Limited dosage forms• Limited strengths• Home health care• Hospice• Nonavailable drug products/combinations
– Discontinued Drugs– Drug Shortages*
• Orphan drugs• Veterinary compounding• New therapeutic approaches• Special Patient Populations
SPECIAL PATIENT POPULATIONS
• Pediatrics• Geriatrics• Bioidentical Hormone
Replacement Therapy• Pain Management• Dental Patients• Environmentally & Cosmetic
Sensitive• Sports Injuries• Veterinary Compounding– Small, Large, Herd, Exotic,
Companion
Why is there so much compounding?
• Loss of manufactured drug products• Office use• Drug shortages• Limited drug products for children and
the elderly• Topical/transdermal administration is
increasing
Compounded Gummy Bears
II. Who governs compounding?
Responsible for Compounding
• State Boards of Pharmacy• FDA• USP Standards
III. Expected Growth and the Future of Compounding
Expected Growth
• Growth in compounding pharmacies to continue
• Discontinued drugs will continue• Drugs in short supply will continue• Alternative drug delivery methods• Dosing adjustment• Short-dated (unstable) drugs• Pediatric formulations lacking
Pharmacogenomics
• Based on the individuals human genome
• Better selection of drugs• Better selection of dose• Better selection of excipients• Compounding may play a
major role!
Compounded Popsicles
IV. Importance of Quality Standards
Quality Standards
• Documentation• Standard Operating Procedures• Analytical Testing• Uniform, Tested Formulas• Accreditation• Certification
V. How I can help you
How I can help you
• Adjust for allergies• Convert tablets/capsules into liquids• Compound topical gels, creams, etc• Make better tasting oral liquids• Other
Thank You!
Any Questions?