The PerkinElmer® Clarus® 560 D Gas Chromatograph/MassSpectrometer (GC/MS) combines the dependable diffusion-pump and electron ionization (EI) capabilities of the high-performance Clarus 600 D MS with the robust Clarus 500 GC,enabling laboratories to conduct reliable and cost-effectiveroutine analyses.

It offers state-of-the-art electronics for the fastest scanningrates and widest mass range, coupled with the most robust,flexible GC autosampler, intuitive touch-screen interface andtwo GC detector channels, while maintaining a compact foot-print for minimal bench space.

With the Clarus 560 D GC/MS, PerkinElmer delivers on yourexpectations through outstanding dependability, precision,performance and cost for everyday GC/MS applications.Advanced technology and ease-of-use mean you’ll maximizeyour uptime.

Clarus 560 D Gas Chromatograph/Mass Spectrometer – dependableresults, again and again

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State-of-the-art electronics provide the fastest scanning rates and increased productivity

Easy-maintenance design, utilizingtools such as a plug-and-play ionsource

The latest in TurboMass™ GC/MSsoftware, including over 70 reporttemplates and customizable reporting

Reliable GC with the most robust,flexible autosampler, a variety ofinjector/detector options, plus anintuitive touch-screen interface

Compact footprint maximizeslaboratory bench space

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Rugged design for maximum uptime

The Clarus 560 D GC/MS is built tough to deliverreliability, reduced costs and easy maintenance.

Our exclusive gold-component technology enhancesoverall instrument stability and significantly reducesdowntime by minimizing contamination.

Design logic saves maintenance time

The logical design of the Clarus 560 D GC/MS meansthat you save time on routine maintenance tasks.

• Quick source changeover reduces the risk of contami-nating the quadrupole analyzer: you have easy accessto the ion source from the front of the instrumentwithout exposing the ion optics or vacuum manifold.

• Routine cleaning of electron ionization (EI) innersource: no wire connections needed.

• Filament replacement is quick and easy due to therobust filament system’s self-aligning design, whichalso means consistent performance, analysis afteranalysis.

• Cleanable RF-only prefilters are easy to maintain:located in front of the quadrupole analyzer.

• Intelligent diffusion-pump electronics and hardwarefor maximum uptime and dependable operation.

Design controls maximize system safeguards

Built-in controls in the Clarus 560 D GC/MS reducebreakdowns and lower operating and repair costs.

• Sealed, long-life photomultiplier detector lowers operat-ing costs: eliminates expensive and contamination-proneelectron multipliers that need periodic replacement.

• Unique programmable pneumatic control (PPC) safe-guards the system from column damage and ion-source contamination: automatically turns off the GC oven and transfer-line heating should carrier-gas pressure drop.

• Independent control of the instrument ion source andtransfer-line temperatures maximizes spectral quality:reduces contamination and protects thermally labilecompounds from uncontrolled fragmentation. Thetemperatures can be set up to 350 ˚C.

• Power outages will not damage the system: the Clarus560 D GC/MS can be attached to a nitrogen purgewhich prohibits oxygen from entering the systemduring venting. This minimizes contamination andspeeds pump-down.

Updated diffusion-pump vacuum technologyprovides reliable operation

The Clarus 600 D GC/MS offers the latest in fail-safediffusion-pump design with a reliable vacuum inside the mass analyzer chamber. This, combined with newsoftware programming, provides enhanced dependability.

• The air-cooled oil diffusion pump is combined with apowerful mechanical backing pump to achieve optimalGC/MS vacuum conditions.

• Updated diffusion-pump system design uses toolssuch as innovative baffles and valves to ensure systemintegrity and maximize system uptime.

• Controlled by unique software to provide seamlesspump-down and venting of the mass analyzer; intelli-gent software uses fail-safe features to allow systemventing only when the pump is cooled and ready,preventing potential damage to the analyzer fromimproper manual venting.

Innovative tools boost laboratory efficiency

The Clarus 560 D GC/MS features innovative and uniqueproductivity-enhancing tools that help laboratories operateeffectively and efficiently.

Fast scanning for the most accurate and precisedata ever

The Clarus 560 D GC/MS acquires more spectra (up to65 scans/second) across a GC peak than most GC/MSsystems. Up to 100 scans/second is achieved for Selected

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Figure 1. Clarus 560 D mass analyzer.

Figure 2. Diffusion-pump venting sequence.

Ion Monitoring (SIM). The result is the most accurateand precise data ever, easily beating the generallyaccepted criteria of at least 7-10 data points per chroma-tographic peak, for performance unmatched by any othercompetitive quadrupole GC/MS system.

Improve productivity and sensitivity with SIFIscanning

With a powerful process called Selected Ion and Full Ion (SIFI™) scanning, SIM data is collected whilesimultaneously acquiring data in the full-scan mode.First implemented by PerkinElmer in 1998, SIFI pro-vides significant laboratory benefits. Because only a singleinjection is required, laboratories will incur savings inproductivity and sample preparation. Additionally, itprovides laboratories the ability to detect and quantifycompounds difficult to determine at low levels withgreater accuracy and sensitivity, and finally the ability to reach SIM detection limits and full-scan librarysearching in a single run.

Gain flexibility and automation capability with the integrated autosampler

The integrated Clarus GC autosampler provides a mech-anically robust, dependable system with the flexibilityand automation capability you need. It provides completeapplication flexibility, accommodating three syringesizes (0.5, 5.0 and 50 µL) and three injection speeds(slow, normal and fast). Its smart design assures efficientutilization of the gas chromatograph, providing unob-structed access to either injection port, allowing anycombination of analyses. It offers built-in quality assur-ance, as optical sensors consistently monitor systemperformance. The GC touch screen delivers smooth navi-gation: with multilingual capability, including errormessages, so you can work in the language of yourchoice.

TurboMass software drives routine orresearch-intensive analyses

Data acquisition

TurboMass™ GC/MS software makes it easy to acquiredata for either qualitative or quantitative sample analysis.

• Sample-centric software is intuitive to learn and use.

• Methods are easy to set up and store for the routine user.

• Project-based organization collects all the necessarymethod information and data in one location, facilitatingarchiving.

• Data collection uses a simple checklist. Just check offthe desired steps and press the “OK” button to initiatedata collection and reporting.

• Use the AutoBuild feature to speed development of quantitative methods. Just a few clicks and thenecessary information are transferred from the chro-matogram, spectrum and library search results to themethod.

Chromatogram and spectrum viewers for easydata screening during and after acquisition

Screening data using the powerful chromatogram and spectrum viewers is a simple and easy process.Chromatograms and spectra can be displayed at anypoint during or after acquisition, saving you valuabletime during post-run processing. Chromatograms fromup to 16 different acquisitions (including the one cur-rently being acquired, with real-time updating) can bedisplayed simultaneously with a single drag-and-click of

Figure 4. SIFI scanning ensures accurate identification, while simulta-neously providing enhanced quantifiable sensitivity from the selectedion signal.

Figure 3. Chromatographic signal at fast scan speed (red) compared toslow scan speed (green).

the mouse. This enables quick comparison to referencechromatograms. Single mouse clicks allow selection ofextracted mass ions, chromatogram overlays, peak in-tegration and more. Spectrum-peak averaging and back-ground subtraction of unwanted ions are flexible and easy,as is verification of spectrum quality to environmentalmethod criteria. Similarly, the spectrum viewer allowsfor spectral comparison of up to 14 spectra from thesame or different chromatograms using single mouseclicks at any time during acquisition or post run. Mass-spectral library search is just a single mouse click away.

Efficient, effective post-run data review ensurescorrect peak selection and compliance

Data review is an important preliminary step in anyquantitative application, to ensure that only correctlyintegrated and identified peaks are used in quantitationand further evaluation. The interactive data-reviewenvironment speeds this step of the process.

Automated tuning optimizes mass spec performance

Tuning the mass spectrometer is critical to ensure thatgood library-searchable spectra are generated fromanalyses. TurboMass software automatically tunes themass spectrometer using a new-generation proprietarytune (UltraTune®), providing enhanced stability andreproducibility.

GC detector support adds flexibility

You can use two additional GC detectors simultaneouslywith your Clarus GC/MS system. All acquisition, displayand quantitation can be performed by TurboMass software.You also have the option of using our TotalChrom® Chro-matography Data Systems (CDS) workstation or client/server software for these processes.

Environmental data evaluation and reportingpackage speeds quality results

TurboMass software is especially designed to meet the strict quality-assurance (QA) and quality-control (QC) compliance requirements of environmental and other types of laboratories. Maximize your lab’s productivity with the superior data review,evaluation and report-generating capabilities ofTurboMass software, while ensuring complete compliance with required methodologies.

Fast, simple and flexible reporting completes the process

Most labs must present their data in an attractive, stan-dardized format for reporting to internal or externalclients. TurboMass software includes over 70 standardtemplates, allowing report generation with just a fewclicks. Report templates are designed to meet the specificneeds of labs conducting environmental, forensic, clinicalor toxicological diagnostics, as well as general chemicalanalysis. Examples of reports are included to make thechoice simple.

TurboMass software is LIMS-compatible for simple datatransfer of worklists from LIMS and GC/MS back to yourLIMS: standard report templates for data transfer areprovided to smooth the path to your LIMS, either before or after method QC evaluation.

Figure 5. TIC (total ion chromatogram), extracted ions (121 and 106),and TIC integration.

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Figure 6. Interactive data review.

Hardware

Mass range 1.0-1200 u (amu)

Detector Sealed long-life photomultiplier

Analyzer Quadrupole with prefilter: 131 mm x 12 mm circular rods; 16 mm x 12 mm prefilter rods

Mass stability ±0.1 m/z mass accuracy over 48 hours

EI voltage 10-100 eV

Pump Air-cooled oil diffusion

Vacuum gauge Standard, single wide-range gauge for all pumping options

GC transfer line Settable from 50 ˚C to 350 ˚C

Source Temperature settable from 50 ˚C to 350 ˚C; No wires – plug and play

Calibrant gas PFTBA (FC-43), Tris(perfluoroheptyl)-s-triazine for high mass calibration (optional), or user selectable

MSVent Optional accessory for MS isolation

Performance

Scan rate Fully variable up to 12,500 amu/sec

Maximum Up to 65 scans/second full scan, depending on mass range

Acquisition rate Up to 100 samples/second, selected ion monitoring (SIM)

Linear dynamic range Electronic: 106 -107 depending on acquisition rate

Scan functions/run 32 sets (full scan/SIM) of up to 32 ions per function

Data system

Methods Electronically transferable between Clarus 600, Clarus 560, Clarus 500, TurboMass Gold and TurboMass GC/MS systems

Acquisition MS detector with two GC detectors (optional)

SIFI Simultaneous full-scan data acquisition with selected ion monitoring (SIM)

UltraTune autotune User selectable: standard (BFB/DFTPP) or custom tuning

Reporting Environmental: standard – Forensic: standard – Customizable: standard

Sensitivity

Test Amount Detection Limits (S/N)EI full scan 1 pg of octafluoronaphthalene 100:1 RMS

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Clarus 560 D MS Specifications

For a complete listing of our global offices, visit www.perkinelmer.com/lasoffices

©2007 PerkinElmer, Inc. All rights reserved. The PerkinElmer logo and design are registered trademarks of PerkinElmer, Inc. SIFI, TurboMass and TurboMatrix are trademarks andPerkinElmer, Clarus, UltraTune and TotalChrom are registered trademarks of PerkinElmer, Inc. or its subsidiaries, in the United States and other countries. All other trademarks not owned by PerkinElmer, Inc. or its subsidiaries that are depicted herein are the property of their respective owners. PerkinElmer reserves the right to change this document at any time withoutnotice and disclaims liability for editorial, pictorial or typographical errors.

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Optional libraries and software

Libraries NIST Mass Spectral LibraryWiley Mass Spectral LibraryPfleger/Maurer/Weber Drugs, Pollutants, Pesticides and Metabolites Library

Software Ion Signature Deconvolution MS software

Physical

Power 120 VAC ±10% @ 50/60 Hz ±1% 1000 VA; 230 VAC ±10% @ 50/60 Hz ±1% 1000 VA

Operating 10 ˚C to 30 ˚Ctemperature

Relative humidity 20-80%, non-condensing

Weight Clarus 560 D GC/MS: 46.3 kg (102 lb); Forepump: 25.9 kg (57 lb)

Dimensions (HxWxD) 51 x 33 x 74 cm (20 x 13 x 29 in)With Clarus 500 GC and Autosampler: 79 x 99 x 74 cm (31 x 39 x 29 in)

Create an integrated analytical solution

Combine the Clarus 560 D GC/MS with our market-leading TurboMatrix™ Headspace or Thermal Desorption samplehandling, flexible user-friendly software and world-class service and support for an integrated, complete analyticalsolution.

PerkinElmer – the clear choice in gas chromatography

PerkinElmer is the only chromatography supplier who develops, manufactures, supports and services every product it offers to provide a truly integrated system. This means one expert supplier – with best-in-class instruments and aworld-class service and support organization – can address all of your applications and troubleshooting needs, fromsample handling to data handling.