Peng Li, PhD Curriculum Vitae

Contact Information

School of Nursing NB 485D University of Alabama at Birmingham

Phone: (205) 996 0376 Fax: (205) 996 9165 Email: pli@uab.edu

Birmingham, AL 35294

------------------------------------------------------------------------------------------------------------------------------------ Education

2014 Ph.D., Biostatistics; University of Alabama at Birmingham Dissertation: Small sample inference of cluster randomized trials 2011 M.S., Biostatistics; University of Alabama at Birmingham Thesis: Versatile gene-based association analysis of obesity in a European American

population 2005 M.S., Computer Science; University of Alabama at Birmingham 1996 M.S., Biochemistry; Wuhan University, China 1993 B.S., Biology; Wuhan University, China

------------------------------------------------------------------------------------------------------------------------- Current Employment

Assistant Professor, School of Nursing, UAB

------------------------------------------------------------------------------------------------------------------------- Professional Experience

04/2019 ~ Associate Scientist, UAB the Nutrition Obesity Research Center (NORC) 09/2018 ~ Assistant Professor, School of Nursing, UAB 11/2018 ~ Scientist, UAB Comprehensive Diabetes Center 06/2015 ~ Scientist, UAB Center for Clinical and Translational Science (CCTS) 06/2015 ~ 09/2018 Scientist, Department of Biostatistics, School of Public Health, UAB 09/2014 ~ 06/2015 Statistician, the Office of Energetics, School of Public Health, UAB 05/2011 ~ 08/2014 Graduate Student Assistant, Department of Biostatistics, UAB 08/2007 ~ 04/2011 Research Associate, Vascular Biology & Hypertension Program, UAB 07/2000 ~ 07/2007 Research Assistant, Vascular Biology & Hypertension Program, UAB 08/1996 ~ 06/2000 Research Assistant, Division of Biochemistry, Cardiovascular Institute & Fuwai

Hospital, Beijing, China

------------------------------------------------------------------------------------------------------------------------- Workshop and Short Courses

2015 First Short Course on Strengthening Causal Inference in Behavioral Obesity Research, UAB 2015 Second Short Course on Mathematical Sciences in Obesity Research, UAB 2013 ASA Biopharmaceutical Section FDA-Industry Statistics Workshop, Washington D.C.

2011 1st NIGMS Short Course on Statistical Genetics and Genomics, UAB 2010 SQL Development Certificate, UAB

------------------------------------------------------------------------------------------------------------------------------------ Research Interest

Study design; Causal inference; Cluster randomized trial; Randomized control trial; Correlated data analysis; GEE; GLMM; Small sample inference; Power and sample size estimation; Claims and Registry data (SEER, NCDB, Medicare); Missing data

Nursing research; Palliative care; Surgery and organ transplantation; Cancer research; Obesity, nutrition and metabolic diseases; Bone diseases; Cardiovascular diseases; Health behavior of children; Statistical genetics

------------------------------------------------------------------------------------------------------------------------------------ Teaching

2019 – Instructor, NUR 700, Clinical Data Mgmt & Analysis, School of Nursing, UAB 2019 – Instructor, NST 758, Inferential Statistics I, School of Nursing, UAB 2016 – 2017 Tutor, BST632 Statistical Theory II, Department of Biostatistics, UAB 2015 – 2017 Tutor, BST631 Statistical Theory I, Department of Biostatistics, UAB 2011 – 2013 Teaching Assistant, BST631 Statistical Theory I; Department of Biostatistics, UAB 1993 – 1996 Teaching Assistant, Laboratories for Biochemistry, Enzyme Chemistry and Protein Chemistry;

Wuhan University

------------------------------------------------------------------------------------------------------------------------------------ Professional Membership

American Statistical Association Eastern North American Region/International Biometric Society

American Heart Association

------------------------------------------------------------------------------------------------------------------------------------ Honors and Awards

2015 Science Unbound Foundation’s 2014 Best Paper by a UAB student in obesity-related research. "Genetic association analysis of 30 genes related to obesity in a European American population” Int J Obes (Lond). 2014, 38(5):724-9. doi: 10.1038/ijo.2013.140.

2014 Charles R. Katholi Distinguished Dissertation Award, Department of Biostatistics at the UAB School of Public Health,

2011 – 2014 NHLBI T32 Pre-doctoral Fellowship (T32HL079888), 2008 Travel Award, Southern Section-American Federation for Medical Research (SAFMR) and

the Southern Society for Clinical Investigation. 2005 Trainee Research Award, Southern Section-American Federation for Medical Research

(SAFMR) and the Southern Society for Clinical Investigation.

2001 Second Award of Chinese Medical Science and Technology Award, from Chinese Medical Association (#200102156U0101): “Study of the function of RAS in the heart hypertrophy by the chymase and rennin transgenic models”.

------------------------------------------------------------------------------------------------------------------------------------ Academic Services Internal Statistical Service

CTSA Consortium Scientific Review Committee Scientific Review Committee, Department of Medicine, UAB Biostat Drop-In Clinic: Weekly in the Center for Clinical and Translational Science (CCTS), UAB

Data Safety and Monitoring Board

Trial: “Assessment of a Community Support Worker Intervention for PLWH in Rural Ethiopia.” ClinicalTrials.gov Identifier: NCT02448394 Other Identifier: R01 MH105290-01 Responsible party: University of Minnesota - Clinical and Translational Science Institute PI: Alan R Lifson, MD, MPH Email: lifso001@umn.edu

Invited Statistical Reviewer for Journals

Clinical Trials Statistics in Medicine Journal of Statistical Computation and Simulation Computational Statistics and Data Analysis Biometrical Journal BMC Medical Research Methodology International Journal of Obesity Obesity American Journal of Clinical Nutrition (Top reviewer at 2015, 2016, 2017) European Journal of Clinical Investigation Surgery for Obesity and Related Diseases PLOS ONE

------------------------------------------------------------------------------------------------------------------------------------ Invited Lectures

• “Cluster Randomized Trials”. Scientific and Statistical Principles Session in NUTRITION 2018, June 9, 2018, Boston, MA

• “Missing Data in Randomized Clinical Trials”. Fourth Short Course on Mathematical Sciences in Obesity Research, UAB. Jun 19, 2017

• “Missing Data in Randomized Clinical Trials”. Third Short Course on Mathematical Sciences in Obesity Research, UAB. Jun 21, 2016

• “Design & Cluster Randomized Trials and Accommodating Clustering in Animal Studies”. Second Short Course on Mathematical Sciences in Obesity Research, UAB. Jun 22, 2015

• “Missing Data in Randomized Clinical Trials”. Second Short Course on Mathematical Sciences in Obesity Research, UAB. Jun 22, 2015

• “What If Missing Not at Random in Obesity Research?” in “Open Problems in Obesity”. Mathematics Colloquium, Department of Mathematics, UAB. Feb 27, 2015

• “Generalized Estimating Equation in Analyzing Cluster-Randomized Trials with Small Number of Clusters”. Center of Biostatistics and Bioinformatics, the University of Mississippi Medical Center. April 30, 2014

------------------------------------------------------------------------------------------------------------------------------------ Research Supports Active NIH/NCATS 1UL1TR001417 Robert P. Kimberly (PI) 08/18/15-03/31/19 UAB Center for Clinical and Translational Science (CCTS) Role: Biostatistician NPCRC 000515918 Erin Currie (PI) 07/01/17-06/30/19 Do Health Disparities in the Deep South Impact Neonatal Palliative Care? Role: Biostatistician NIH/NINDS 1R21NS101672 Jianhua Zhang (PI) 09/30/17-08/31/19 Lysosomal enhancement strategies in dopaminergic neurodegeneration Role: Co-I (Biostatistician) NPCRC 000515918 Yasemin Turkman (PI) 07/01/18-06/30/20 Enhancing Access and Acceptability of Palliative Care Services for Underserved Persons with Advanced Cancer in the Deep South Role: Biostatistician NIH/NCI R21 CA223126 Lyse Norian (PI) 07/01/18-06/30/20 Identifying Outcome Mediators of Calorie Restriction Mimetic use in Renal Cancer Role: Co-I (Biostatistician) DoD CA171145 Jianmei Leavenworth (PI) 09/01/18-08/31/21 Boosting the systemic and in situ CD4+ T-cell responses to malignant gliomas by oncolytic HSV virotherapy Role: Co-I (Biostatistician) NIH/NIDDK 1U01DK120379 Anath Shalev (PI) 09/15/18-07/31/22 Development of an early diagnostic biomarker and novel treatment strategy for t1d Role: Collaborator (Biostatistician)

Completed HudsonAlpha Inst for Biotechnology Bruce R. Korf (PI) 08/01/17-09/30/18 Clinical Sequencing across Communities in the Deep South (CSER2) Role: Biostatistician

NIH/FIC 1R21TW010310 David C. Schwebel (PI) 09/21/15-08/31/18 Delivering virtual reality through mobile platforms: child pedestrian safety training in china. Role: Co-I (Biostatistician) NIH/NIDDKD R03 DK106432 Derek DuBay (PI) 07/15/15-05/31/18 A Pragmatic Video Intervention to Promote African American Organ Donor Registration at the Department of Motorized Vehicles Role: Biostatistician UAB SPARC Beth Comeaux (PI) 01/01/17-12/31/17 Development of an Evidence-Based Tool that Would Define a Benchmark for End of Care and Initiation of Hospice for Patients with Hepatocellular Carcinoma with or Without Cirrhosis Role: Biostatistician NIH/AHRQ 4U19HS021110-05 Kenneth G. Saag (PI) 09/01/15-08/31/17 UAB deep south arthritis and musculoskeletal CERTS. Role: Biostatistician NIH/NICHD 5R21HD075960 David C. Schwebel (PI) 01/01/16-09/30/16 A website to teach children safety with dogs: development and evaluation Role: Biostatistician NIH/NHLBI T32 HL079888 Hemant Tiwari (PI) 05/01/11-08/09/14 UAB Biostatistics pre-doctoral training program Role: Trainee

------------------------------------------------------------------------------------------------------------------------- Publications

Chapter in book 1. Oparil S, Li P, Chen YF. Pulmonary vascular remodeling in pulmonary hypertension: evidence from animal

models to man. In: Clozel M and Rubin LJ. Ed. The Endothelin System in Cardiopulmonary Diseases. Switzerland: Friedrich Reinhardt Verlag; 2004: 143-158

Peer-reviewed papers on statistics and study design 1. Li P, Stuart EA. Best (but oft-forgotten) practices: missing data methods in randomized controlled nutrition trials.

Am J Clin Nutr. 2019; 109(3):504-508. PMID:30793174. DOI: https://doi.org/10.1093/ajcn/nqy271 2. Murillo AL, Affuso O, Peterson CM, Li P, Wiener HW, Tekwe CD, Allison DB. Illustration of Measurement Error

Models for Reducing Bias in Nutrition and Obesity Research Using 2-D Body Composition Data. Obesity (Silver Spring). 2019; 27(3):489-495. doi: 10.1002/oby.22387. PubMed PMID: 30672124.

3. Ejima K, Pavela G, Li P, Allison DB. Generalized lambda distribution for flexibly testing differences beyond the mean in the distribution of a dependent variable like body mass index. Int J Obes (Lond). 2018; 42(4):930-933. NIHMSID: NIHMS910065. doi: 10.1038/ijo.2017.262.

4. George BJ, Li P, Lieberman HR, Pavela G, Brown AW, Fontaine KR, Jeansonne MM, Dutton GR, Idigo AJ, Parman MA, Rubin DB, Allison DB. Randomization to Randomization Probability: Estimating Treatment Effects under Actual Conditions of Use. Psychol Methods. 2018; 23(2):337-350. NIHMSID: NIHMS850811. doi: 10.1037/met0000138. PMID:28406674

5. Ejima K, Li P (Co-first author), Smith DL, Nagy TR, Kadish I, van Groen T, Dawson JA, Yang Y, Patki A, Allison DB. Observational Research Rigor Alone Does Not Justify Causal Inference. Eur J Clin Invest. 2016; 46(12):985-993. doi: 10.1111/eci.12681

6. George BJ, Beasley TM, Brown AW, Dawson J, Dimova R, Divers J, Goldsby TU, Heo M, Kaiser KA, Keith SW, Kim MY, Li P, Mehta T, Oakes JM, Skinner A, Stuart E and Allison DB. Common scientific and statistical errors in obesity research. Obesity, 2016, 24: 781–790. doi: 10.1002/oby.21449

7. Ivanescu AE, Li P, George B, Brown AW, Keith SW, Dheeraj Raju D, Allison DB. The importance of prediction model validation and assessment in obesity and nutrition research. Int J Obes (Lond). 2016; 40(6):887-94. NIHMSID: NIHMS727944 PMID:26449421 PMCID:PMC4826636

8. Li P, Stuart EA, Allison DB. Multiple Imputation: a flexible tool for handling missing data. JAMA. 2015; 314(18):1966-7. doi: 10.1001/jama.2015.15281. PMID:26547468

9. Brown AW, Li P, Bohan Brown MM, Kaiser KA, Keith SW, Oakes JM, Allison DB. Best (but oft forgotten) practices: designing, analyzing, and reporting cluster randomized controlled trials. Am J Clin Nutr. 2015, 102(2):241-8. doi: 10.3945/ajcn.114.105072. PMID:26016864

10. Li P, Redden DT. Comparing denominator degrees of freedom approximations for the generalized linear mixed model in analyzing binary outcome in small sample cluster-randomized trials. BMC Med Res Methodol. 2015; 15(1):38. PMID: 25899170. PMCID: PMC4458010

11. Li P, Redden DT. Small sample performance of bias-corrected sandwich estimators for cluster-randomized trials with binary outcomes. Stat Med. 2015, 34(2):281-296. PubMed PMID: 25345738; PMCID: PMC4268228.

Peer-reviewed papers on collaborative research, as biostatistician

12. Wang J, Rousso C, Christensen BI, Li P, Kau CH, MacDougall M, Lamani E. Ethnic differences in the root to crown ratios of the permanent dentition. Orthod Craniofac Res. 2019 Jan 16. doi: 10.1111/ocr.12288. [Epub ahead of print] PubMed PMID: 30650237

13. Paluri R, Madan A, Li P, Jones B, Saleh M, Jerome M, Miley D, Keef J, Robert F. Phase 1b trial of nintedanib in combination with bevacizumab in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2019 Jan 2. doi: 10.1007/s00280-018-3761-y. [Epub ahead of print] PubMed PMID: 30603797.

14. McCaskill GM, Clay OJ, Li P, Kennedy RE, Burgio KL, Brown CJ. Kilocalorie Expenditure and All-Cause Mortality in Older Male Veterans and Non-Veterans. Journal of Aging and Physical Activity. 2019; 27(1):67-72

15. Wills BW, Pearson J, Hsu A, Li P, Shah A, Naranje S. Preoperative hematocrit on early prosthetic joint infection and deep venous thrombosis rates in primary total hip arthroplasty: A database study, J Clin Orthop Trauma. 2019, 10(1):124-127

16. Lee SR, Shrestha K, Staggers J, Li P, Naranje SM, Shah A, Impact of Timeto-Surgery from Injury on Postoperative Infection and Deep Vein Thrombosis in Periprosthetic Knee Fractures, Chin J Traumatol. 2018, 21(6):329-332.

17. Richardson MB, Li P, Gohlke JM, and Allison DB. Effects of indoor thermal environment on human food intake, productivity, and comfort: pilot randomized crossover trial. Obesity (Silver Spring). 2018, 26(12):1826-1833. doi: 10.1002/oby.22328.

18. Ovalle F, Grimes T, Xu G, Patel AJ, Grayson TB, Thielen LA, Li P and Shalev A. Verapamil and beta cell function in adults with recent-onset type 1 diabetes. Nature Medicine, 2018; 24(8):1108-1112. doi: 10.1038/s41591-018-0089-4.

19. Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters R, Delahaye F, Hubbard G, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran P, Cohen P, Barzilai N, and Huffman D. Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. Nature Communications. 2018; 9(1):2394. doi: 10.1038/s41467-018-04805-5.

20. Wills BW, Sheppard ED, Smith WR, Staggers JR, Li P, Shah A, Lee SR, Naranje SM. Impact of operative time on early joint infection and deep vein thrombosis in primary total hip arthroplasty. Orthop Traumatol Surg Res. 2018; 104(4):445-448

21. Schwebel DC, Wu Y, Li P, Severson J, He Y, Xiang H, Hu G. Evaluating Smartphone-Based Virtual Reality to Improve Chinese Schoolchildren's Pedestrian Safety: A Nonrandomized Trial. J Pediatr Psychol. 2018; 43(5): 473-484 doi: 10.1093/jpepsy/jsx147.

22. Danila MI, Outman RC, Rahn EJ, Mudano AS, Redden DT, Li P, Allison JJ, Anderson FA, Wyman A, Greenspan SL, LaCroix AZ, Nieves JW, Silverman SL, Siris ES, Watts NB, Miller MJ, Curtis JR, Warriner AH, Wright NC and Saag KG. Evaluation of a Multi-modal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis: A Randomized Clinical Trial. J Bone Miner Res. 2018; 33(5):763-772. doi:10.1002/jbmr.3395

23. Salas AA, Li P, Parks K, Lal CV, Martin CR, Carlo WA. Early progressive feeding in extremely preterm infants: a randomized trial. Am J Clin Nutr. 2018; 107(3):365-370. doi: 10.1093/ajcn/nqy012.

24. Lutful Kabir F, Ambalavanan N, Liu G, Li P, Solomon GM, Lal CV, Mazur M, Halloran B, Szul T, Gerthoffer WT, Rowe SM, Harris WT. microRNA-145 Antagonism Reverses TGF-β Inhibition of F508del CFTR Correction in Airway Epithelia. Am J Respir Crit Care Med. 2018; 197(5):632-643. doi: 10.1164/rccm.201704-0732OC.

25. Cannon A, Chen MJ, Li P, Boyd KP, Theos A, Redden DT, Korf B. Cutaneous neurofibromas in Neurofibromatosis type I: a quantitative natural history study. Orphanet J Rare Dis. 2018; 13(1):31. doi: 10.1186/s13023-018-0772-z.

26. Matin T, Naseemuddin M, Shoreibah M, Li P, Kyanam Kabir Baig K, Wilcox CM, Peter S. Case series on multimodal endoscopic therapy for gastric antral vascular ectasia, a tertiary center experience. World J Gastrointest Endosc. 2018; 10(1): 30-36

27. Bertrand LA, Thomas LJ, Li P, Buchta CM, Boi SK, Orlandella RM, Brown JA, Nepple KG, Norian LA. Obesity as defined by waist circumference but not body mass index is associated with higher renal mass complexity. Urol Oncol. 2017; 35(11):661.e1-661.e6. doi: 10.1016/j.urolonc.2017.06.058.

28. Schwebel DC, Johnston A, Shen J, Li P. Evaluating Otto the Auto: Does Engagement in an Interactive Website Improve Young Children’s Transportation Safety? Int J Environ Res Public Health. 2017, 14(7), 804; doi:10.3390/ijerph14070804

29. White JA, Gray SH, Li P, Simpson HN, McGuire BM, Eckhoff DE, Abdel Aal AMK, Saddekni S and Dubay DA. Current guidelines for chemoembolization for hepatocellular carcinoma: Room for improvement? Hepatology Communications, 2017; 1: 338–346. doi:10.1002/hep4.1046

30. Gray SH, White JA, Li P, Kilgore ML, Redden DT, Abdel Aal AK, Simpson HN, McGuire B, Eckhoff DE, Dubay DA. A SEER Database Analysis of the Survival Advantage of Transarterial Chemoembolization for Hepatocellular Carcinoma: An Underutilized Therapy. J Vasc Interv Radiol. 2017; 28(2):231-237.e2. doi: 10.1016/j.jvir.2016.09.022. PMID:27939085

31. Schwebel DC, Li P, McClure LA, Severson J. Evaluating a Website to Teach Children Safety with Dogs: A Randomized Controlled Trial. Int J Environ Res Public Health. 2016, 13(12): 1198; doi:10.3390/ijerph13121198

32. Saddekni MB, Saag KG, Dudenbostel T, Oparil S, Calhoun DA, Sattui SE, Feig DI, Muntner P, Redden DT, Foster PJ, Rahn EJ, Biggers SR, Li P, Gaffo AL. The Effects of Urate Lowering Therapy on Inflammation, Endothelial Function, and Blood Pressure (SURPHER) Study Design and Rationale. Contemporary Clinical Trials. 2016; 50:238-244. doi: 10.1016/j.cct.2016.08.016. PMID:27587282

33. Dover LL, Jacob R, Wang TN, Richardson JH, Redden DT, Li P, DuBay D. Improved Postoperative Survival for Intraductal growth Subtype of Intrahepatic Cholangiocarcinoma. The American Surgeon, 2016; 82(11): 1133-9.

34. Dudenbostel T, Ghazi L, Liu M, Li P, Oparil S, Calhoun DA. Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension. Hypertension. 2016; 68(4):995-1003. doi: 10.1161/HYPERTENSIONAHA.116.07806. PMID:27528066

35. Bernhard M, Li P, Allison DB, Gohlke JM. Warm ambient temperature decreases food intake in a simulated office setting: A pilot randomized controlled trial. Front. Nutr. 2015, 2:20. doi: 10.3389/fnut.2015.00020. PMID: 26322311, PMCID: PMC4500895

36. Dudenbostel T, Acelajado MC, Pisoni R, Li P, Oparil S, Calhoun D. Refractory hypertension: evidence of heightened sympathetic activity as a cause of antihypertensive treatment failure. Hypertension, 2015; 66(1):126-33. DOI: 10.1161/HYPERTENSIONAHA.115.05449. PMID: 25987662. PMCID: PMC4465856

37. Li P, Tiwari HK, Lin WY, Allison DB, Chung WK, Leibel RL, Yi N, Liu N. Genetic association analysis of 30 genes related to obesity in a European American population. Int J Obes (Lond). 2014, 38(5):724-9. doi: 10.1038/ijo.2013.140. PubMed PMID: 23900445; PMCID: PMC3909018

Communications on obesity and nutrition research, particularly on cluster randomized trials

38. Wood AC, Brown AW, Li P, Oakes JM, Pavela G, Thomas DM, Allison DB. A Comment on Scherr et al "A Multicomponent, School-Based Intervention, the Shaping Healthy Choices Program, Improves Nutrition-Related Outcomes". J Nutr Educ Behav. 2018; 50(3):324-325. doi: 10.1016/j.jneb.2017.12.011

39. George BJ, Goldsby TU, Brown AW, Li P, Allison DB. Unsubstantiated conclusions from improper statistical design and analysis of a randomized controlled trial. Int J Yoga. 2016; 9(1):87-8. doi: 10.4103/0973-6131.171726

40. Thomas DM, Brown A, Dawson JA, Li P, Heymsfield SB, Allison DB. Letter to the Editor: Exceptional Data in Paper on "The effect of meridian massage on BM, BMI, WC and HC in simple obesity patients: a randomized controlled trial". World J Acupunct Moxibustion. 2015; 25(1):66-67.

41. Bernhard MC, Li P, Allison DB, Gohlke JM. Corrigendum: Warm Ambient Temperature Decreases Food Intake in a Simulated Office Setting: A Pilot Randomized Controlled Trial. Front Nutr. 2015; 2:36. doi: 10.3389/fnut.2015.00036.

42. Li P, Brown AW, Oakes JM, Allison DB. Comment on "School-Based Obesity Prevention Intervention in Chilean Children: Effective in Controlling, but not Reducing Obesity". J Obes. 2015; 183528. doi: 10.1155/2015/183528.

43. Li P, Brown AW, Oakes JM, Allison DB. Comment on "Intervention Effects of a School-Based Health Promotion Programme on Obesity Related Behavioural Outcomes". J Obes. 2015; 708181. doi: 10.1155/2015/708181

44. Zalewski BM, Chmielewska A, Szajewska H, Keithley JK, Li P, Goldsby TU, Allison DB. Correction of data errors and reanalysis of "The effect of glucomannan on body weight in overweight or obese children and adults: a systematic review of randomized controlled trials". Nutrition. 2015; 31(7-8):1056-7. doi: 10.1016/j.nut.2015.02.008

45. Li P, Brown AW, Dawson JA, Kaiser KA, Brown MM, Keith SW, Oakes JM, Allison DB. Concerning Sichieri R, Cunha DB: Obes Facts 2014; 7:221–232. The Assertion that Controlling for Baseline (Pre-Randomization) Covariates in Randomized Controlled Trials Leads to Bias is False. Obes Facts. 2015; 8(2):127-9.

Peer-reviewed papers (Role as laboratory scientist)

46. Zhao X, Zhang W, Xing D, Li P, Fu J, Gong K, Hage FG, Oparil S, Chen YF. Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol. 2013; 305(4):H590-8. doi: 10.1152/ajpheart.00571.2012. PMCID: PMC3891247

47. Xing D, Li P (Co-first), Gong K, Yang Z, Yu H, Hage FG, Oparil S, Chen YF. Endothelial cells overexpressing interleukin-8 receptors reduce inflammatory and neointimal responses to arterial injury. Circulation. 2012; 125(12):1533-41. doi: 10.1161/CIRCULATIONAHA.111.078436. PMID: 22361324;PMCID: PMC3685282

48. Gong K, Xing D, Li P, Aksut B, Ambalavanan N, Yang Q, Nozell SE, Oparil S, Chen YF. Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling. Am J Physiol Lung Cell Mol Physiol. 2011; 301(6):L899-907. doi: 10.1152/ajplung.00062.2011. PMID: 21926264

49. Gong K, Xing D, Li P, Hilgers RH, Hage FG, Oparil S, Chen YF. cGMP inhibits TGF-beta signaling by sequestering Smad3 with cytosolic beta2-tubulin in pulmonary artery smooth muscle cells. Mol Endocrinol. 2011; 25(10):1794-803. doi: 10.1210/me.2011-1009. PMID: 21868450

50. Gong K, Chen YF, Li P, Lucas JA, Hage FG, Yang Q, Nozell SE, Oparil S, Xing D. Transforming growth factor-β inhibits myocardial PPARγ expression in pressure overload-induced cardiac fibrosis and remodeling in mice. J Hypertens. 2011; 29(9):1810-9. doi: 10.1097/HJH.0b013e32834a4d03. PMID:21836474. PMCID: PMC3325019

51. Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen YF. Inhibition of transforming growth factor-beta signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart. Am J Physiol Heart Circ Physiol. 2010; 298(2):H424-32. doi: 10.1152/ajpheart.00529.2009. PMID:19933419. PMCID: PMC2822586

52. Ambalavanan N, Nicola T, Li P, Bulger A, Murphy-Ullrich J, Oparil S, Chen YF. Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions. Pediatr Res. 2008; 63(1):26-32. doi:10.1203/PDR.0b013e31815b690d. PMID:18043506. PMCID: PMC2517580

53. Li P, Wang D, Lucas J, Oparil S, Xing D, Cao X, Novak L, Renfrow MB, Chen YF. Atrial natriuretic peptide inhibits transforming growth factor beta-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ Res. 2008; 102(2):185-192. doi: 10.1161/CIRCRESAHA.107.157677. PMID: 17991884

54. Ambalavanan N, Li P, Bulger A, Murphy-Ullrich J, Oparil S, Chen YF. Endothelin-1 mediates hypoxia-induced increases in vascular collagen in the newborn mouse lung. Pediatr Res. 2007; 61(5 Pt 1):559-64. doi:10.1203/pdr.0b013e318045beae. PMID:17413856. PMCID: PMC2517238

55. Li P, Oparil S, Novak L, Cao X, Shi W, Lucas J, Chen YF. ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells. J Appl Physiol. 2007; 102(1):390-8. doi: 10.1152/japplphysiol.00468.2006. PMID:17038494

56. Franco V, Chen YF, Feng JA, Li P, Wang D, Hasan E, Oparil S, Perry GJ. Eplerenone prevents adverse cardiac remodelling induced by pressure overload in atrial natriuretic peptide-null mice. Clin Exp Pharmacol Physiol. 2006; 33(9):773-9. doi: 10.1111/j.1440-1681.2006.04434.x. PMID:16922805

57. Chen YF, Feng JA, Li P, Xing D, Ambalavanan N, Oparil S. Atrial natriuretic peptide-dependent modulation of hypoxia-induced pulmonary vascular remodeling. Life Sci. 2006; 79(14):1357-65. doi: http://dx.doi.org/10.1016/j.lfs.2006.03.051. PMID:16714036

58. Chen YF, Feng JA, Li P, Xing D, Zhang Y, Serra R, Ambalavanan N, Majid-Hassan E, Oparil S. Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling. J Appl Physiol. 2006; 100(2):564-71. doi: 10.1152/japplphysiol.00595.2005. PMID:16223981

59. Li P, Oparil S, Feng W, Chen YF. Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. J Appl Physiol. 2004; 97(4):1550-8; discussion 1549. doi: 10.1152/japplphysiol.01311.2003. PMID:15121739

60. Li P, Oparil S, Sun JZ, Thompson JA, Chen YF. Fibroblast growth factor mediates hypoxia-induced endothelin-- a receptor expression in lung artery smooth muscle cells. J Appl Physiol. 2003; 95(2):643-51; discussion 863. doi: 10.1152/japplphysiol.00652.2002. PMID:12851419

61. Wang D, Oparil S, Feng JA, Li P, Perry G, Chen LB, Dai M, John SW, Chen YF. Effects of pressure overload on extracellular matrix expression in the heart of the atrial natriuretic peptide-null mouse. Hypertension. 2003; 42(1):88-95. doi: 10.1161/01.HYP.0000074905.22908.A6. PMID:12756220

62. Li P, Chen PM, Wang SW, Chen LY. Time-dependent expression of chymase and angiotensin converting enzyme in the hamster heart under pressure overload. Hypertens Res. 2002; 25(5):757-62. doi: http://dx.doi.org/10.1291/hypres.25.757. PMID:12452330

63. Chen LY, Li P, He Q, Jiang LQ, Cui CJ, Xu L, Liu LS. Transgenic study of the function of chymase in heart remodeling. J Hypertens. 2002; 20(10):2047-55. PMID: 12359984

64. Zhang PH, Li P, Han XN, Zhang XC, Chen LY. Inhibitory effect of Xuezhikang on matrix metalloprotease-2 secreted by macrophage. Chin J Cardiol. 2001; 29(8): 497-99.

65. Li P, Chen LY. Function of chymase in the heart angiotensin II formation in transgenic mice. Chin Sci Bulletin, 2001; 46(11): 922-25.

66. Wang X, Li P, Chen LY. Activities of angiotensin converting enzyme and chymase-like in the heart of chymase transgenic mice. Basic Med Sci Clin (china). 2000; 20(3): 90-93.

67. Chen PM, Chen LY, Fan MZ, Ni XH, Li P. Establishment of hamster myocardial hypertrophic model and detection of chymase and ACE gene expression in the left ventricle. Chin J Hypertens. 2000; 8(1):52-55.

68. Li P, He Q and Chen LY. Intron deletion in heterologous gene in transgenic mice and its effect on gene expression. Chin J Biochem Mol Biol, 1999; 15(5): 704-708.

69. Li P and Chen LY. Tissue-specific expression of MLC2-chymase fusion gene in the transgenic mice --- Quantification by competitive PCR. Chin J Biochem Mol Biol, 1999; 15(4):629-632.

70. He Q, Li P, Jiang LQ, Chen LY. A new method of screening transgenic animal: PCR and its products sequencing. Prog Biochem Biophys. 1997; 24(6):552-554

71. Li P and Zou GL. Studies on the enzyme-like activity of Bleomycin A5. J Wuhan Univ, 1997; 43(4):517-522.

72. Li P, Zou GL and Shen X. Studies on the transient fluorescence induced by the bleomycin A5-iron complex in solution with oxygen. Acta Biophysica Sinica, 1997; 13(1):128-132.

73. Li P and Zou GL. Function of the hydroxyl radical in bleomycin A5-induced DNA degradation. Acta Biochimica et Biophysica Sinica. 1997; 29(1):92-97

74. Li P, Zou GL and Shen X. Studies on the chemiluminescence induced by rapid mixing bleomycin A5 with Fe2+ and Oxygen. Acta Biophysica Sinica, 1996; 12(4):719-723.

75. Li P and Zou GL. Sequence-selective binding of bleomycin A5 to DNA. J Wuhan Univ, 1996; 42(2):764-768 76. Zou GL, Hu P and Li P. Studies on preparation and properties of stearic acid-modified superoxide dismutase.

Chin Biochem J, 1996; 12(1):64-67. 77. Zou GL, Xia L and Li P. Preparation and characterization of superoxide dismutase soluble in organic solvents.

Acta Biochimica et Biophysica Sinica. 1996; 28(1):83-88. 78. Zou GL, Xu CB, Hu P and Li P. Studies on the preparation and properties of gelatin microspheres containing

superoxide dismutase. J Wuhan Univ, 1995; 41(4):517-520. 79. Zou GL, Qiu MY, Li P and Wei MH. Comparative studies on the methods for the preparation of superoxide

dismutase. J Wuhan Univ, 1995; No.2 special issue on biophysics: 16-19. 80. Zou GL and Li P. Progress on Bleomycin. Chemistry of Life, 1994; 14(5):42-44. Conference presentation (Abstracts, Presenter if first-authored)

1. Anusiewicz CV, Li P, Patrician P. (2019, April). Workplace Bullying among Alabama Inpatient Nurses: A Cross-sectional Study, 2019 AAOHN National Conference, Jacksonville, FL

2. Anderson JL, Li P, Bukusi EA, Darbes LA, Hatcher AM, Helova A, Kwena K, Musoke PL, Oyaro P, Rogers AJ, Turan JM. Estimating the Moderating Effects of Maternal Depressive Symptoms in an Intervention to Promote HIV-Prevention Health Behaviors in Pregnant/Postpartum Women in Rural Southwestern Kenya , 10th Anniversary Conference: Global Mental Health Research without Borders, 2019, April , Bethesda, MD

3. Currie, ER., Li P, Boss R, Wolfe J, Perna SJ, Buckingham S, McKillip K, Dionne-Odom JN, Ejem D, Antia L, & Bakita, M. (2019, March). Access to pediatric palliative care in minority and rural deep south neonatal intensive care (ICU) patients: Patterns of care from 2009-2017. Poster presented at the American Academy of Hospice and Palliative Medicine and Hospice and Palliative Nurses Association Annual Assembly, Orlando, FL. *Hospice and Palliative Nurses Poster Award

4. Deupree JP, Peterson D, Li P. (2018, October). Associations Between Patient Education Materials, Consumer Satisfaction Rates, CMS 30-day Readmission Penalties and the Size of Hospitals. Health Literacy Annual Research Conference, Boston University, MA

5. Schwebel DC, Wu Y, Li P, Severson J, He Y, Xiang H, Hu G. Can we teach children to cross streets using virtual reality delivered by smartphone? results from china. Injury Prevention 2018. 24(Suppl 2):A51.1-A51

6. Everett AS, Dulaney C, Li P, Bredel M, Robert F, Fiveash J, Boggs DH. No Survival Benefit with Prophylactic Cranial Irradiation in Extensive Stage Small Cell Lung Cancer: An Analysis from the National Cancer Database. ASTRO 2018. San Antonio, TX

7. Abou‐Arraj RV, Hsu J, Kaur M, Geisinger M, Hardy S, Li P, Geurs NC. A prospective randomized clinical trial to compare free gingival grafts and connective tissue grafts around implants lacking keratinized mucosa. Journal of Clinical Periodontology. 2018, 45(S19):20. https://doi.org/10.1111/jcpe.40_12913

8. Burgio K, Kraus S, Johnson T, Markland, Vaughan C, Li P, Redden D, Goode P. Combined Behavioral and Drug Treatment of Lower Urinary Tract Symptoms in Men: The COBALT Randomized Controlled Trial. ICS 2018 Philadelphia

9. Schwebel DC, Wu Y, Li P. Severson J, He Y, Xiang H, Hu G. Can we teach children to cross streets using virtual reality delivered by smartphone? Results from China. SAFETY 2018 Bangkok

10. Dulaney C, Fiveash J, Li P, Boggs DH. Pilot study of stereotactic radiosurgery and tumor treating fields for patients with small cell lung cancer brain metastases. J Radiat Oncol. 2018, https://doi.org/10.1007/s13566-018-0348-5

11. Burgio K, Kraus S, Johnson II TM, Markland A, Vaughan C, Li P, Redden D, Goode P. PD59-01 Combined Behavioral and Drug Treatment of Lower Urinary Tract Symptoms in Men: The Cobalt Randomized Trial. The Journal of Urology. 2018; 199(4S): e1139

12. Manne A, Reddy S, Heslin M, Jacob R, Vickers SM, Contreras CM, Kasi A, Christein J, Li P, Posey J, Paluri RK. Retrospective review of FOLFIRINOX in local advanced pancreatic cancer: Single institution experience. J Clin Oncol 2017, 35 (15_suppl): e15714-e15714

13. Dulaney C, Fiveash J, Li P, Boggs H. Radiation therapy patterns of care for non-small cell lung cancer brain metastases: an analysis of the national cancer database. Neuro-Oncology. 2017; 19(suppl_6): vi41

14. Dover L, Li P, Saddekni S, White J, Shen S, Paluri R, and Jacob R. Optimal Timing of Stereotactic Radiation Therapy Following Transarterial Chemoembolization for Locally Advanced Hepatocellular Carcinoma. International Journal of Radiation Oncology • Biology • Physics , 2017; 99(2 ): E144

15. Danila MI, Rahn EJ, Mudano AS, Outman RC, Li P, Redden DT, Anderson FA, Greenspan SL, LaCroix AZ, Nieves JW, Silverman SL, Siris ES, Watts NB, Ladores S, Meneses K, Curtis JR and Saag KG. Factors associated with readiness for adopting osteoporosis treatment change. Arthritis & Rheumatology. 2017; 69(S10):

16. Danila MI, Rahn EJ, Mudano AS, Outman RC, Li P, Redden DT, Anderson FA, Greenspan SL, LaCroix AZ, Nieves JW, Silverman SL, Siris ES, Watts NB, Ladores S, Meneses K, Curtis JR and Saag KG. Temporal increase in side effect concerns of osteoporosis medications among women with previous fractures. Arthritis & Rheumatology. 2017; 69(S10):

17. Danila MI, Rahn EJ, Mudano AS, Outman RC, Li P, Redden DT, Anderson FA, Greenspan SL, LaCroix AZ, Nieves JW, Silverman SL, Siris ES, Watts NB, Ladores S, Meneses K, Curtis JR and Saag KG. Reasons for Stopping Osteoporosis Medications among Women with Previous Fractures. Journal of Bone And Mineral Research 2017; 32, S249-S250

18. Nandagopal L, Heslin MJ, Porterfield JR, Jacob R, Li P, Posey J, Paluri R. Adjuvant therapy associated with improved survival in gall bladder cancer: a single institution retrospective study. Cancer Research. 2017; 77(13 Supplement):3283-3283

19. Manne A, Reddy S, Li P, Contreras CM, Christein J, Vickers SM, Heslin M, Jacob R, Wang TN, Kasi A, Posey J, Paluri RK. Clinical outcomes of early-stage ampullary carcinoma: A single institutional experience. J Clin Oncol 2017:35 (suppl 4S; abstract 456)

20. Danila MI, Outman RC, Rahn EJ, Mudano AS, Redden DT, Li P, Anderson FA, Anderson JP, Greenspan SL, LaCroix AZ, Nieves JW, Silverman SL, Siris ES, Watts NB, Miller MJ, Curtis JR, Warriner AH, Wright NC and Saag KG. The Activating Patients at Risk for Osteoporosis Study: A Randomized Trial within the Global Longitudinal Study of Osteoporosis in Women Cohort. Arthritis & Rheumatology. 2016; 68(S10):322

21. Saddekni MB, Saag SG, Dudenbostel T, Calhoun DA, Feig DI, Muntner P, Foster PJ, Biggers SR, Rahn E, Li P, Oparil S, Redden DT, Gaffo AL. Serum urate and its association with Blood Pressure and Endothelial Dysfunction in young adults. Arthritis & Rheumatology. 2016; 68(S10):2287

22. Saddekni MB, Gaffo AL, Foster PJ, Rahn EJ, Biggers SR, Li P, Saag KG. Serum urate and its association with race in young adults: Baseline analysis from a randomized clinical trial. Arthritis & Rheumatology. 2016; 68(S10):2297

23. Richardson MCB, Li P, Gohlke JM, Allison, DB. Effects of the indoor thermal environment on human food intake: a pilot randomized controlled trial. TOS 2016

24. Dover L, DuBay D, Li P, Redden D, Saddekni S, Shen S, Jacob R. Protocol RAD 0902: A Pilot Study of Transarterial Chemoembolization Followed by Stereotactic Radiation Therapy for Locally Advanced Hepatocellular Carcinoma. Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2S):S143.

25. Richardson MCB, Allison DB, Li P, Gohlke JM. Thermal exposure influences food intake in a sedentary office setting. Journal of the Alabama Academy of Science, 2015; 86(2), 112-114.

26. Li P, Kadish I, van Groen T, Dawson JA, Patki A, Allison DB. Disparate weight gain associations with self-selected and randomly assigned food consumption in mice: Can one confidently infer causality from even the ultimately well-conducted observational study? TOS 2015.

27. Li P, Allison DB, George B, Schwartz TS, Leibel RL, Carmody J. Potential effects of embryo genotype on maternal glucose homeostasis: an example of “fetal drive”. TOS 2015.

28. Dudenbostel T, Acelajado MC, Li P, Oparil S, Calhoun DA. Non‐dipper Pattern is Associated with Urinary Metanephrines in Patients with Refractory Hypertension. HBPR 2014; Hypertension, 64:(Suppl 1)

29. Li P, Redden D. Generalized estimating equation in analyzing group-randomized trials with limited number of groups. ENAR 2014.

30. Dudenbostel, T, Calhoun D, Li P. Increased urinary sodium levels in a large cohort of obese patients and paradox aldosterone regulation after sodium loading. ICE/ENDO 2014.

31. Hage FG, Hilgers R, Li P, Yang Z, Oparil S, Chen Y-F. Endothelial Cell Transfusion Protects Against Chronic Kidney Disease-Induced Endothelial Dysfunction in Nephrectomized Rats. Circulation 2011; 124.

32. Li P, Xing D, Gong K, Hage F, Oparil S, Chen Y. Targeted Delivery of Endothelial Cells Overexpressing IL8RA and IL8RB Receptors Promotes Structural and Functional Recovery of the Left Ventricle in Rats Following Myocardial Infarction. ASH 2011

33. Gong K, Xing D, Li P, Ambalavanan N, Oparil S, Chen Y-F. ANP-cGMP-PKG activation inhibits TGFβ-induced smad3 nuclear translocation by increasing smad3 binding to cytosolic β2-tubulin in rat pulmonary arterial smooth muscle cells. The Journal of Clinical Hypertension. 2011:13(7):535

34. Gong K, Chen Y-F, Li P, Zhang W, Hage F, Ambalavanan N, Oparil S, Xing D. PPARg Agonist Inhibits, and PPARg Antagonist Exacerbates, Pressure Overload-Induced Cardiac Fibrosis and Dysfunction. ASH, 2011

35. Gong K, Xing D, Li P, Yang Q, Oparil S, Chen Y-F. Activation of PPAR gamma by rosiglitazone inhibits pressure overload-induced cardiac hypertrophy and improves diastolic dysfunction in mice. Faseb Journal 2011; 25.

36. Gong K, Xing D, Li P, Hilgers RH, Hage FG, Oparil S, Chen Y-F. cGMP Inhibits TGF-beta Signaling by Sequestering Smad3 with Cytosolic beta 2-Tubulin in Pulmonary Artery Smooth Muscle Cells. Molecular Endocrinology 2011; 25: 1794-1803.

37. Gong K, Xing D, Li P, Aksut B, Ambalavanan N, Yang Q, Nozell SE, Oparil S, Chen Y-F. Hypoxia induces downregulation of PPAR-gamma in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-beta signaling. American Journal of Physiology-Lung Cellular and Molecular Physiology 2011; 301: L899-L907.

38. Gong K, Chen Y-F, Li P, Lucas JA, Hage FG, Yang Q, Nozell SE, Oparil S, Xing D. Transforming growth factor-beta inhibits myocardial PPAR gamma expression in pressure overload-induced cardiac fibrosis and remodeling in mice. Journal of Hypertension 2011; 29: 1810-1819.

39. Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen Y-F. Inhibition of transforming growth factor-beta signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart. American Journal of Physiology-Heart and Circulatory Physiology 2010; 298: H424-H432.

40. Li P, Xing D, Gong K, Zhang W, Hage F, Oparil S, Chen Y-F. Targeted Delivery of Endothelial Cells by Overexpressing Interleukin-8 Receptors Inhibits Neointimal Responses to Vascular Injury: Novel Mechanism of Vasoprotection. Circulation 2010; 122.

41. Gong K, Li P, Lucas J, Xing D, Aksut B, Hage F, Yang Q, Nozell S, Oparil S, Chen Y. Disruption of transforming growth factor beta(tgf beta) signaling blocks pressure overload-induced downregulation of endogenous peroxisome proliferator-activated receptor gamma(ppar gamma) expression in heart. Journal of Investigative Medicine 2010; 58: 443-444.

42. Lucas JA, Miller AP, Zhang Y, Li P, Oparil S, Chen Y. Overexpression of dominant negative transforming growth factor (tgf)-beta type ii receptor (dntgf beta rii) attenuates pressure overload-induced cardiac remodeling and dysfunction. Journal of Investigative Medicine 2009; 57: 301-301.

43. Li P, Gong K, Lucas J, Zhang Y, Yang Q, Oparil S, Chen Y-F. TGF-beta Downregulates PPARgamma Gene Expression in Pulmonary Arterial Smooth Muscle Cells (PASMCs): Novel Mechanism of Hypoxia-induced Pulmonary Vascular Remodeling. Circulation 2009; 120: S1022-S1022.

44. Lucas JA, Miller AP, Zhang Y, Li P, Oparil S, Chen Y-F. Blocking of Transforming Growth Factor (TGF)-beta Signaling Exacerbates Pressure Overload-induced Left Ventricular Remodeling and Dysfunction. Circulation 2008; 118: S483-S484.

45. Li P, Wang D, Lucas J, Oparil S, Xing D, Cao X, Novak L, Renfrow MB, Chen Y-F. Atrial natriuretic peptide inhibits transforming growth factor beta-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ Res 2008; 102: 185-192.

46. Li P, Renfrow M, Lucas J, Oparil S, Chen Y. Protein kinase G (PKG) over-phosphorylate smad3: Potential inhibitor of TGF-beta-induced cardiac fibrosis and remodeling. Journal of Investigative Medicine 2008; 56: 371-371.

47. Ambalavanan N, Nicola T, Li P, Bulger A, Murphy-Ullrich J, Oparil S, Chen Y-F. Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions. Pediatric Research 2008; 63: 26-32.

48. Li P, Oparil S, Novak L, Cao X, Shi W, Lucas J, Chen Y-F. ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells. Journal of Applied Physiology 2007; 102: 390-398.

49. Ambalavanan N, Li P, Bulger A, Murphy-Ullrich J, Oparil S, Chen Y-F. Endothelin-1 mediates hypoxia-induced increases in vascular collagen in the newborn mouse lung. Pediatric Research 2007; 61: 559-564.

50. Miller AP, Robertson C, Xing D, Li P, Chen Y-F, Chatham JC, Oparil S. The role of O-GlcNAcylation in aging-related loss of estrogenic vasoprotection. Circ Res 2006; 99: 1282-1282.

51. Franco V, Chen Y-F, Feng JA, Li P, Wang D, Hasan E, Oparil S, Perry GJ. Eplerenone prevents adverse cardiac remodelling induced by pressure overload in atrial natriuretic peptide-null mice. Clinical and Experimental Pharmacology and Physiology 2006; 33: 773-779.

52. Chen Y-F, Wang D, Xing D, Li P, Cao X, Oparil S. ANP-cGMP-PKG signaling blocks TGF-beta 1-induced myofibroblast transformation and phospho-Smad3 nuclear translocation, but not Smad3 phosphorylation, in mouse cardiac fibroblasts. Circ Res 2006; 99: E46-E46.

53. Chen Y-F, Li P, Novak L, Cao X, Oparil S. Atrial natriuretic peptide (ANP) signaling inhibits extracellular matrix expression in rat pulmonary arterial smooth muscle cells (PASMCs) by blocking transforming growth factor (TGF)-betainduced nuclear translocation of phosphorylated Smad2 and Smad3. Journal of Hypertension 2006; 24: 153-153.

54. Chen Y-F, Feng J-A, Li P, Xing D, Ambalavanan N, Oparil S. Atrial natriuretic peptide-dependent modulation of hypoxia-induced pulmonary vascular remodeling. Life Sci 2006; 79: 1357-1365.

55. Chen YF, Feng JA, Li P, Xing DQ, Zhang Y, Serra R, Ambalavanan N, Majid-Hassan E, Oparil S. Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling. Journal of Applied Physiology 2006; 100: 564-571.

56. Li P, Oparil S, Majid-Hassan E, Hsiung MK, Shi WB, Cao X, Chen YF. ANP and cGMP block TGF-beta-induced nuclear translocation of phosphorylated Smad2 and Smad3 and expression of extracellular matrix protein in rat pulmonary arterial smooth muscle cells. Circulation 2005; 112: U114-U114.

57. Li P, Oparil S, Chen YF. Atrial natriuretic peptide and cyclic guanosine monophosphate block the stimulatory effects of transforming growth factor beta 1 on extracellular matrix messenger ribonucleic acid expression in cultured pulmonary artery smooth muscle cells. Journal of Investigative Medicine 2005; 53: S318-S318.

58. Feng JA, Oparil S, Li P, Xing DQ, Serra R, Chen YF. Transgenic mice with transforming growth factor (TGF)-beta type II receptor dysfunction have attenuated hypoxia-induced pulmonary hypertension and remodeling. Journal of the American College of Cardiology 2005; 45: 378A-378A.

59. Feng JA, Li P, Xing D, Serra R, Oparil S, Chen YF. Transgenic mice with transforming growth factor beta type II receptor dysfunction have attenuated hypoxia-induced pulmonary hypertension and remodeling. Journal of Investigative Medicine 2005; 53: S291-S291.

60. Feng JA, Li P, Xing D, Serra R, Oparil S, Chen YF. Transgenic mice with transforming growth factor beta type II receptor dysfunction have attenuated hypoxia-induced pulmonary hypertension and remodeling. Journal of Investigative Medicine 2005; 53: S327-S327.

61. Chen YF, Feng JA, Li P, Xing DQ, Serra R, Ambalavanan N, Oparil S. TGF-beta and ANP signaling play opposing roles in hypoxia-induced pulmonary vascular remodeling. Circulation 2005; 112: U209-U210.

62. Sheridan AE, Feng JA, Wang D, Li P, Oparil S, Chen YF. Atrial natriuretic peptide modulates extracellular matrix expression in pathologic but not physiologic left ventricular hypertrophy. Journal of Investigative Medicine 2004; 52: S263-S263.

63. Li P, Oparil S, Feng WG, Chen YF. Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. Journal of Applied Physiology 2004; 97: 1550-1558.

64. Li P, Oparil S, Chen YF. Fibroblast growth factor upregulates periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. Journal of Investigative Medicine 2004; 52: S288-S289.

65. Li P, Oparil S, Chen YF. Fibroblast growth factor upregulates periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. American Journal of Hypertension 2004; 17: 172A-172A.

66. Wang DJ, Oparil S, Feng JA, Li P, Perry G, Chen LB, Dai MR, John SWM, Chen YF. Effects of pressure overload on extracellular matrix expression in the heart of the atrial natriuretic peptide-null mouse. Hypertension 2003; 42: 88-95.

67. Li P, Oparil S, Sun JZ, Thompson JA, Chen YF. Fibroblast growth factor mediates hypoxia-induced endothelin-A receptor expression in lung artery smooth muscle cells. Journal of Applied Physiology 2003; 95: 643-651.

68. Li P, Oparil S, Chen YF. Hypoxia upregulates expression of periostin, a novel extracellular matrix protein, in rat lung via p13 kinase-MAP kinase signaling pathway. Journal of the American College of Cardiology 2003; 41: 308A-308A.

69. Wang DJ, Feng JA, Li P, Oparil S, Perry G, Chen YF. Effects of transverse aortic constriction on cardiac gene expression in the atrial natriuretic peptide knockout mouse. Hypertension 2002; 40: 420-420.

70. Li P, Oparil S, Chen YF. Fibroblast growth factor-1 stimulates endothelin-A receptor expression in pulmonary arterial smooth muscle cells via transcriptional activation. Faseb Journal 2002; 16: A1118-A1118.

Last update: 5/21/2019