pdb history structural biology highlightscdn.rcsb.org/rcsb-pdb/v2/about-us/pdb-history-print.pdf ·...

1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 PDB established 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2025 2024 2023 2022 2021 2020 Early structures include carboxypeptidase chymotrypsin cytochrome b5 hemoglobin lactate dehydrogenase myoglobin rubredoxin subtilisin trypsin inhibitor IUCr policy on data deposition published PDB moves to RCSB PDB MSD at the EBI becomes a deposition center for PDB data 10,000 th structure is released Osaka University opens a PDB data deposition center wwPDB established by RCSB PDB, PDBe, PDBj 50 th anniversary of the PDB New Validation Reports provided for NMR, 3DEM BMRB joins wwPDB Deposition of experimental data (X-ray, NMR) mandatory 50,000 th structure is released PDB40 Symposium Deposition of chemical shift data mandatory First tRNA structures determined (Kim et al., 1973; Robertus et al., 1974) First DNA (Z-DNA) in PDB (Wang et al., 1979) First B-DNA structure determined (Drew et al., 1981) Nobel prize awarded to A. Klug for Development of crystallographic electron microscopy and discovery of the structure of biologically important nucleic acid-protein complexes Nobel prize awarded to J. Deisenhofer, R. Huber, H. Michel for The determination of the 3D structure of of a photosynthetic reaction centre First NMR structure released in PDB: protein BDS-I (Driscoll et al., 1989) First EM structure released in PDB: bacteriorhodopsin (Henderson et al., 1990) Nobel prize awarded to P.D. Boyer, J.E. Walker, J.C. Skou for Elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP) and discovery of an ion-transporting enzyme EMDB established at MSD-EBI First ribosome structures in PDB (Ban et al., 2000; Carter et al., 2000; Schluenzen et al., 2000) Nobel prize awarded to K. Wüthrich for Development of NMR spectroscopy for determining the 3D structure of biological macromolecules in solution Last PDB archive distribution by postal mail (8 DVDs) Implementation of PDB Entry Versioning PDB-Dev: A Prototype System for Integrative/Hybrid Structural Models announced in Structure Nobel Prize awarded to J. Dubochet, J. Frank, R. Henderson for Developing Cryo-electron Microscopy for the High-resolution Structure Determination of Biomolecules in Solution UNESCO celebrates the International Year of Crystallography >100,000 structures in the archive OneDep: New system for Deposition-Validation-Biocuration Nobel Prize awarded to M. Karplus, M. Levitt and A. Warshel for the Development of Multiscale Models for Complex Chemical Systems Nobel prize awarded to V. Ramakrishnan, T.A. Steitz, A.E. Yonath for Studies of the structure and function of the ribosome First structure from an X-ray Free Electron Laser (Chapman et al., 2011) First release of remediated data Nobel prize awarded to R.D. Kornberg for Studies of the molecular basis of eukaryotic transcription Nobel prize awarded to R. MacKinnon for Potassium channels Validation Reports required for manuscript submission to Journal of Biological Chemistry Nobel Prize awarded to R.J. Lefkowitz and B.K. Kobilka for Studies of G-protein-coupled Receptors PDB History Structural Biology Highlights Nobel Prize awarded to Frances H. Arnold for the Directed Evolution of Enzymes >150,000 structures in the archive

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Page 1: PDB History Structural Biology Highlightscdn.rcsb.org/rcsb-pdb/v2/about-us/pdb-history-print.pdf · crystallographic electron microscopy and discovery of the structure of biologically

1979

1978

1977

1976

1975

1974

1973

1972

1971

1970

PDB established

1989

1988

1987

1986

1985

1984

1983

1982

1981

1980

1999

1998

1997

1996

1995

1994

1993

1992

1991

1990

2009

2008

2007

2006

2005

2004

2003

2002

2001

2000

2019

2018

2017

2016

2015

2014

2013

2012

2011

2010

2029

2028

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2025

2024

2023

2022

2021

2020

Early structures include carboxypeptidase

chymotrypsin cytochrome b5

hemoglobin lactate dehydrogenase

myoglobin rubredoxin

subtilisin trypsin inhibitor

IUCr policy on data deposition published

PDB moves to RCSB PDB

MSD at the EBI becomes a deposition center for PDB data

10,000th structure is released

Osaka University opens aPDB data deposition center

wwPDB established byRCSB PDB, PDBe, PDBj

50th anniversary of the PDB

New Validation Reports provided for NMR, 3DEM

BMRB joins wwPDB

Deposition of experimental data (X-ray, NMR) mandatory50,000th structure is released

PDB40 SymposiumDeposition of chemical shift data mandatory

First tRNA structures determined(Kim et al., 1973; Robertus et al., 1974)

First DNA (Z-DNA) in PDB (Wang et al., 1979)

First B-DNA structure determined (Drew et al., 1981)

Nobel prize awarded to A. Klug for Development of crystallographic electron microscopy and discovery of the structure of biologically important nucleic acid-protein complexes

Nobel prize awarded to J. Deisenhofer, R. Huber, H. Michel for The determination of the 3D structure of of a photosynthetic reaction centre

First NMR structure released in PDB:protein BDS-I (Driscoll et al., 1989)

First EM structure released in PDB:bacteriorhodopsin (Henderson et al., 1990)

Nobel prize awarded to P.D. Boyer, J.E. Walker, J.C. Skou for Elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP) and discovery of an ion-transporting enzyme

EMDB established at MSD-EBIFirst ribosome structures in PDB (Ban et al., 2000; Carter et al., 2000; Schluenzen et al., 2000)

Nobel prize awarded to K. Wüthrich for Development of NMR spectroscopy for determining the 3D structure of biological macromolecules in solution

Last PDB archive distribution by postal mail (8 DVDs)

Implementation of PDB Entry Versioning

PDB-Dev: A Prototype System for Integrative/Hybrid Structural Models announced in Structure

Nobel Prize awarded to J. Dubochet, J. Frank, R. Henderson for Developing Cryo-electron Microscopy for the High-resolution Structure Determination of Biomolecules in Solution

UNESCO celebrates the International Year of Crystallography

>100,000 structures in the archive

OneDep: New system for Deposition-Validation-Biocuration

Nobel Prize awarded to M. Karplus, M. Levitt and A. Warshel for the Development of Multiscale Models for Complex Chemical Systems

Nobel prize awarded to V. Ramakrishnan, T.A. Steitz, A.E. Yonath for Studies of the structure and function of the ribosome

First structure from an X-ray Free Electron Laser (Chapman et al., 2011)

First release of remediated dataNobel prize awarded to R.D. Kornberg for Studies of the molecular basis of eukaryotic transcription

Nobel prize awarded to R. MacKinnon for Potassium channels

Validation Reports required for manuscript submission to Journal of Biological Chemistry

Nobel Prize awarded to R.J. Lefkowitz and B.K. Kobilka for Studies of G-protein-coupled Receptors

PDB History Structural Biology Highlights

Nobel Prize awarded to Frances H. Arnold for the Directed Evolution of Enzymes>150,000 structures in the archive