4. Discuss the incidence, epidemiology and aetiology of chronic peptic ulcer (Gastric and Duodenal ulcers)

4. Discuss the incidence, epidemiology and aetiology of chronic peptic ulcer (Gastric and Duodenal ulcers)Main aetiological factors: hyperacidity,Helicobactergastritis, duodeno-gastric reflux, NSAIDs, smoking and genetic factors FeaturesGastric UlcerDuodenal ulcer

Incidence13 (more common)

Age distributionIncreases with ageIncreases up to 35 years of age

Social classMore common in low socioeconomic classesEven distribution

Blood groupAO

Acid levelNormal or lowElevated or normal

H. Pylori gastritisAbout 70%95-100%

Source : Underwoods Pathology textbook , page 334.

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