patholgy practical revision - semester 3 [8] - by shy you

7/30/2019 Patholgy Practical Revision - Semester 3 [8] - By Shy You

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Identification [diagnosis]

Organ [State the name of organ]

Say if the organ is complete, cut

opened, cross-sectioned, or only a partof it is present. (Sometimes a group of

organs are present. Ex. Group of lymph

nodes)

Comment [Description]


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10 things to think of [Jar] Number External surface Site Size Shape Colour Consistency

Contents CoverCapsule Cut section


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1. Caseating tuberculous lymphadenitis.2. Non-caseating granuloma.

Gumma of testis

3. Non-caseating granuloma.Gumma of liver

4. Metastasis in Liver.5. Ulcerative carcinoma, Colon.

6. Multiple uterine leiomyomata.

7. Benign (mature) cystic teratoma, Ovary.

8. Benign papilloma, Skin.Compound [Branching], Squamous

9. Squamous cell carcinoma, Skin.

10. Basal cell carcinoma, Skin.- Rodent ulcer

11. Lipoma (benign tumor), Subcutaneous tissue.


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Caseating tuberculous lymphadenitis


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Non-caseating granulomaGumma of testis


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Non-caseating granulomaGumma of testis Organ: Testis & spermatic cord [Section]

Comment:

Testis: Enlarged.

Gumma (lesion):

Multiple in number.

Variable in size.

Colour: Greyish-white. Shape: Serpigenousoutline (irregular).

Consistency: Rubbery.

Well circumscribed.


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Non-caseating granulomaGumma of liver


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Non-caseating granulomaGumma of liver

Organ: Live. [Slice of sectioned liver] Comment:

Liver:

Slightly enlarged.

Irregular external suface.

Gumma:

Single.

Subcapsular (Peripheral) Colour: Greyish-white.

Shape: Serpigenous outline.

Consistency: Rubbery.

Well circumscribed.


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Metastasis in Liver


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Metastasis in Liver Organ: Slice/Piece of liver. [Section]

Comment:

Liver:

Enlarged.

External surface: Irregular.

Metastatic masses:

Uncapsulated.

Irregular sizes and shapes. Invading the surroundings.

Number: Multiple.

Site: Subcapsular(at periphery).

Central umbilications.


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Ulcerative carcinoma, Colon


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Ulcerative carcinoma, Colon Organ: Piece of colon. [Open] Comment:

Tumor:

Single, Large, Ovoid, Non-capsulated,Irregular, Invading the surronding tissues.

Ulcer: Number: Single.

Size: Large. Edge: Everted & Raised.

Margins (Outlines): Irregular.

Floor: Dirty, nectoric.

Base: Hard, fixed, indurated.


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Multiple uterine leiomyomata


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Multiple uterine leiomyomata Organ: Uterus, with adenxia [Section]

Comment: Uterus: Enlarged.

External surface: Irregular (nodular). Narrowing of uterine cavity.

Tumor: Number: Multiple.

Size: Variable. Shape: Regular; oval or rounded.

Capsule: Non-capsulated [False capsule] => Well-defined, well circumscribed.

Cut section: Whorly appearance.


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Benign(mature)cystic teratoma, Ovary


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Benign(mature)cystic teratoma, Ovary

Organ: Ovary.[Open]

Comment:

Ovary:

Enlarged.

Replaced by tumor tissue.

Tumor:

Large.

Cut section: Unilocular cyst. Lumen: Contains hair, bone, teeth, sebaceous

secretions, skin.

B i ill Ski


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Benign papilloma, SkinCompound [Branching], Squamous


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B i ill Ski


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Benign papilloma, SkinPapillary skin lesion Organ: Skin (excisional biopsy), [Cut section]

Comment:

Papilloma:

Large.

Enlarged.

Cut section: central brownish cores.

Covered by skin.


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Squamous cell carcinoma, Skin


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Squamous cell carcinoma, Skin Organ: Piece of skin.

Comment: Tumor:

Malignant.

Single.

Non-Capulated. Invading the surroundings.

Ulcer: Single.

Large.

Edges: Raised & Everted.

Margins: Irregular outline.

Floor: Dirty, necrotic.

Base: Large, fixed, indurated.

Basal cell carcinoma Skin


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Basal cell carcinoma, Skin- Rodent ulcer


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Basal cell carcinoma Skin


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Basal cell carcinoma, Skin- Rodent ulcer

Organ: Piece of skin. Comment:

Malignant tumor: Single.

Small. Non-capsulated.

Rodent ulcer: Number: Single.

Size: Small. Edge: Raised, Inverted (rolled in), beaded.

Floor: Dirty, necrotic.

Margins: Irregular outline.

Base: Hard, indurated.

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Lipoma (benign tumor), Subcutaneous tissue

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Lipoma (benign tumor), Subcutaneous tissue Organ: Piece of skin, subcutaneous tissue.

Comment:

Thin capsule.

Not invading.

Regular.

Colour: Yellow.

Consistency: Soft.

Touch: Greasy.

Appearance: Fatty.

Cut section: Lobulated surface.


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Things to think of [Slide] Cells

Arrangement

Shape

Stroma C.T.

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A. Lipoma.B. Squamous cell carcinoma (SCC).

C. Basal cell carcinoma (BCC).

D. Adenocarcinoma, Colon.

E. Early (Non-caseating) TB.

F. Late (Caseating) TB.

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Lipoma

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Lipoma

Benign tumor Organ: Skin and subcutaneous tissue.

Cells:

Adult, mature, fat cells.

Aggregated, proliferated.

Stroma:

Thin capsule.

Thin traversing connective tissue fibers.


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Squamous cell carcinoma

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Organ: SkinDermis containing tumors. Cells:

Arranged in irregular massescell nestsepithelial pearls.

Masses: Outer layer: Columnar

Middle layer: Polygonal

Inner layer: Flat cells, with central keratinization. Shape: Pleomorphism, hyperchromatism,

few mitotic figures.

Stroma: Scanty C.T. stoma.

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Basal cell carcinoma

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Organ: Skin, ulcerative epidermis. Cells:

Arrangement:

Irregular masses, different in size and shape. Geographical appearance.

Shape:

Tall, columnar/basaloid cells.

Peripheral nuclear palisading manner.

Stroma: Retracted C.T. stroma.

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Adenocrcinoma colon

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Adenocrcinoma colon

Organ: Part of colonic wall. Cells:

Glandular arrangement, of different sizes

and shapes. Multiple, irregular acini.

Shape: Pleomorphism, hyperchromatism,

abundant mitotic figures.

Stroma: C.T. stroma between cells.


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Adenocrcinoma colon


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Adenocrcinoma colon

Normal colon

Adenocarcinoma ofcolon

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Non-Caseating granuloma

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Early TB in a lymph node. Tubercles:

Multiple.

Different in sizes and shapes. Epithelioid macrophages.

(Large, faint cytoplasm, elongated vesicular nucleus)

Multinucleated giant cells:

Nuclei arranged in horse-shoe pattern[Langhans Giant cells]

Nuclei irregularly scattered [Foreign body type]

Non Caseating granuloma


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Non-Caseating granulomaEarly TB



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Tuberculous Caseous Lymphadenitis

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Late TB in a lymph node. Inflammatory cells (epithelioid cells,

lymphocytes, Langhans giant cells): Forming

poorly-developed tubercles. Large area of caseation:

Homogenous, structureless.

Faint, eosinophilic, pink. Granular.



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patholgy practical revision - semester 3 [8] - by shy you

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