partnership with plantform corporation molecular factory

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Partnership with PlantForm Corporation MOLECULAR FACTORY: GRAVITYFLOW 2015 Starting point: PlantForm Corporation: Canadian biotech company producing biosimilar drugs and vaccines through GMO agrobacteria infiltration of the tobacco plant Nicotiana Benthamiana. Intravision patent: Vacuum infiltration of transgenic tobacco PlantForm patent: Biosimilar Herceptin in transgenic tobacco plant.

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Page 1: Partnership with PlantForm Corporation MOLECULAR FACTORY

Partnership with PlantForm CorporationMOLECULAR FACTORY: GRAVITYFLOW2015 Starting point:PlantForm Corporation: Canadian biotech company producing biosimilar drugs and vaccines through GMO agrobacteria infiltration of the tobacco plant Nicotiana Benthamiana.

Intravision  patent:  Vacuum  infiltration  of  transgenic  tobacco

PlantForm  patent:  Biosimilar  Herceptin  in  transgenic  tobacco  plant.

Page 2: Partnership with PlantForm Corporation MOLECULAR FACTORY
Page 3: Partnership with PlantForm Corporation MOLECULAR FACTORY

The GravityFlow system - a “high-tech/ low-tech”

Page 4: Partnership with PlantForm Corporation MOLECULAR FACTORY

The Intravision Timeline:

Projects:

Research:

Eurostar on GMO Barley, ORF, Iceland

Photobiolgy on fish in

aquaculture

Cooperation CESRF

UoGuelph

Photosystem sealed research

chamber.(PS1000)

NSERC grant on Romaine salad

and beans

Photosystem sealed research

chamber.(PS2000)

Intravision GROUP

established

Intravision GREENS

established

New Jersey &Welland facilities

complete

Pilot facility in Paris France

AI Farmerassistant

operational

AI DeepLearning/pattern

Recognition starts

1998 2009 2016 2018 2019 2020 2022

GravityFlow system

invented

We the Roots Toronto pilot operational

Reserach on micro-algae

started

Page 5: Partnership with PlantForm Corporation MOLECULAR FACTORY

Tech-transfer Space Research:2010 Intravision and CESRF cooperation.

The hypobaric Guelph Blue-Box plant chambers developed to understand if terrestrial food-plants can be grown in low at-mospheric pressures / smaller planets than Earth like on Mars

or on the Moon.

Page 6: Partnership with PlantForm Corporation MOLECULAR FACTORY

Snapshots from the development of plant research LED-lighting and research-chambers.

2009: ORF Genetics, Iceland.GMO barely for production of cytokinesEUROSTAR research funding.

Production of food for manned space travel. Canadian Space Agency funding.

Food production prototype for KISR, Kuwait Institute of Scientific Research

LED retrofit of photo-bioreactor,European Space Agency funding.

Simulate environment on a planet - prior to the establishment of an athmosphere.

Sealed Plant Research chamber, prototype, Internal development project

2016: PhotoSystem; CESRF UoGuelph.

2011: INTICE, with CESRF UoGuelph. 2015: MAPS, with CESRF UoGuelph.

2019: MELISSA photo-bioreactor, 2018: Planet Simulator, McMaster U.

Evolution of Intravision Technology:

Page 7: Partnership with PlantForm Corporation MOLECULAR FACTORY

Tech-Transfer from space research!Photo-System 1000 research chamber

The Research Background

Page 8: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:A sealed environment chamber The sealed PhotoSystem chambers are developed in a tech-transfer from CESRF, UoGuelph to Intravision.

With an 9-band LED-light system including UVC, UVB and UVA light, these chambers are unique in creating new un-derstanding and photo-recipes for both food- and medicinal plants.

For development of an AI these chambers are a precision tool to better study plant physiological responses to environment manipulation under multiple parameters including:

• Temperature• Humidity• Carbon dioxide• Oxygen (higher or lower)• Light (quantity, quality)• Nutrients• Plant water status• Insect predation• Pathogen application/response

Page 9: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:The potential of photobiology!• We use colored LED’s to interact with the plants light-senso-ry mechanismens.

• Use designed broadband light spectrums to direct plant growth and to impact the plants secondary metabolites; ap-peracne, texture, taste, human nutrition content.

• Spectrum variable LEDs to optimize different production phases.

Page 10: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:A sealed growth environment Light spectrums on strawberries in vegetative phase.

Page 11: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:A sealed growth environ-ment Correlation between light intensity and CO2 consentrations of:

• 400ppm CO2 (normal air)• 1200ppm CO2

Page 12: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:A sealed growth environment Impact of light spectrums on strawberries in vegetative phase.

1200 ppm CO2

400 ppm CO2

Page 13: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:A sealed growth environment Impact of light spectrums on strawberries in vegetative phase.

Page 14: Partnership with PlantForm Corporation MOLECULAR FACTORY

The PhotoSystem chamber:A sealed growth environment Impact of light spectrums on strawberries in vegetative phase.

Page 15: Partnership with PlantForm Corporation MOLECULAR FACTORY

A “smart” farmers assistant!The understanding of the correlations between a specific plant-genetics biology and growth environ-ment in the PhotoSystem chambers, becomes the INPUT defining the range of environmental regula-tions needed in a commercial GravityFlow system.

The data harvest from the PhotoSystem chambers are then further built on and developed by the AI in the GravityFlow systems.

Currently we are engaged in the first step of this process, building an image database, and establish-ing the-rules for pattern recognition.

Monitoring plant status and applying image pattern recognition with deep learning combined with multi-variable analysis and weighted decision-making - optimizing environment in polynomial time.

… Nutrition comp.… Light spectrum… Light intensity… Air-speed… Air-moisture… Temperature

DEVELOPING A PLATFORM FOR DEEP LEARNING AND AIBuilding an AI-platform:

Page 16: Partnership with PlantForm Corporation MOLECULAR FACTORY

INTRAVISION Greens approach in the USA:Proven ability to produce and compete at large scale with commodity price level:

US$0.78 US$2.12

Cost for INTRAVISION toproduce and deliver one head of

romaine lettuce to NYC*

2017 Peak annualized retailprices advertised by large

grocery chains*

* Based on current NJ facility with 12,000 sq. ft of grow space, operating 52/7 at current prices for water and power and other

inputs.

* www.producerpriceindex.com

Page 17: Partnership with PlantForm Corporation MOLECULAR FACTORY

The US Opportunity

120 million People

5000 kilometer- 3 days

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Romani salad, by far the biggest commodity in the USAField grown in California and Arizona and trucked 5000km to New York

Starting point: The US opportunity

Page 19: Partnership with PlantForm Corporation MOLECULAR FACTORY

Re-Inventing production of food plantsRomaine salad

• From field grown 6 to 9 plants m2 in GravityFlow• From 12 to 9 weeks production time• 10 tier tall this equals 90 plants m2 the last 4-weeks.• Using 1-2% of freshwater compared to field.

Page 20: Partnership with PlantForm Corporation MOLECULAR FACTORY

Re-Inventing production of food plantsRomani salad

Page 21: Partnership with PlantForm Corporation MOLECULAR FACTORY

Plant research and GravityFlow optimization

• NSERC funded proejct at UoGuelph.

• The commercially most important leafy green in the US marketplace; ”the Caesar Salad”.

• MSc student #1 - researching romaine salad for production in a GravityFlow mulitlayer sys-tem.

• MSc student #2 - researching use of excess biomass.

• Work includes developing an image-databa-se for deep machine learning applications.

Page 22: Partnership with PlantForm Corporation MOLECULAR FACTORY

Plant research and GravityFlow optimization

• NSERC funded proejct at UoGuelph.

• PhD student researching beans for producti-on in a GravityFlow mulitlayer system.

• Beans being an important source of protein, cornerstone in vegan diets.

• Work includes developing an image-databa-se for deep machine learning applications.

Page 23: Partnership with PlantForm Corporation MOLECULAR FACTORY

The Global Challenge:How do we feed 10 Billion People?

The Pressure of feeding the world has coincided with the reduction in production cost of LED lighting technology, creating an Ag/tech revolution as an alternative sustainable option to feed the worlds growing demand. Vertical farming is forecast to grow at 23% CAGR

Global increase of living standards

Lack of clean water - the #1. challenge

Rapidly growing urbanisation

Desertification of arable land

Pollution of water, air and ground

Increasing global populationDesertification map.

Page 24: Partnership with PlantForm Corporation MOLECULAR FACTORY

The GravityFlow IMPACT:

• Building 550m x 220m - 9HA• Building 550m x 220m - 9HA• Approximately 96.000 ton of green produce• Approximately 96.000 ton of green produce• 32 MW electrical power to lights + energy for dehumification• 32 MW electrical power to lights + energy for dehumification• 1200m3 water daily recycled from air• 1200m3 water daily recycled from air• 9 MW solar capacity on roof• 9 MW solar capacity on roof

Large scale food production system suited for any environmental condition

Page 25: Partnership with PlantForm Corporation MOLECULAR FACTORY

The large-scale automated plant factory!

Implementation of Scientific research:

Complete System Management:

We at intravision have been developing our technology through corporations and partnerships multiple public and private institutions with the common aim to optimising plant growth and production processes.

2009: ORF Genetics, Iceland.GMO barely for production of cytokines

EUROSTAR research funding.

Production of food for manned space

travel. Canadian Space Agency funding.

Food production prototype for KISR, Kuwait Institute of Scientific Research

LED retrofit of photo-bioreactor, European Space Agency funding.

Production of food for manned space travel, Canadian Space Agency funding.

Sealed Plant Research chamber, prototype, In-ternal development project

2016: PS-1000, with UoGuelph.

Spectrum response pattern analysis

Environmental conditions for analysis

Extracted environmental data

2011: INTICE, with CESRF UoGuelph. 2015: MAPS, with CESRF UoGuelph. 2019: MELISSA photo-bioreactor, 2018: Planet Simulator, Aangstrom.

… Nutrition comp.… Light spectrum… Light intensity… Air-speed… Air-moisture… Temperature

Automated and optimised for maximum results

Nutrient station with UV and particle filters between main and

return

Direct pressure regulated nutrient delivery to each plant

tray

Collection and removal of excess nutrients cycled back to return

tank

The Nutrient Cycle

Up to 95% of the water usage is re-covered, filtered and reused through a

seamless automated nutrient deliver and recovery system.

Dehumidification system returns distilled water to nutrient cycle

Direct delivery system of airflow to plants from both above and

below.

Infusion of CO2 into system for accelerated growth cycles

Regulation of temperature, humidity and O2 levels

The Atmospheric Cycle

Monitors, regulates and optimises the environmental atmospheric condition

within the closed system as to insure the best results.

DEVELOPING A PLATFORM FOR DEEP LEARNING AND AI

Automated and optimised for maximum results

Nutrient station with UV and particle filters between main and

return

Direct pressure regulated nutrient delivery to each plant

tray tray

Collection and removal of excess nutrients cycled back to return

tanktank

The Nutrient Cycle

Up to 95% of the water usage is recovered, filtered and reused through a

seamless automated nutrient deliver and recovery system.

Main Nutrient Tank

Return Nutrient Tank UV Filter

Return Pump

Pump Out

Return water from air dehumidification System

Regulation of Humidity and Temperature

Infusion of C02

Extraction of RoomAtmosphere

Extraction of RoomAtmosphere Atmosphere

Extraction of RoomExtraction of RoomAtmosphere Atmosphere

Dehumidification System

Particle Filter

In the Pipeline

Over 95% less water consumption

Year-round local supply

No pesticides / herbicides Blockchain security

Consistent high-quality product

Lower and less volatile production costs

Page 26: Partnership with PlantForm Corporation MOLECULAR FACTORY

Seeding

Cutting

Germination

Propagation

Transplant

Transplant Harvest

Harvest

Drying

Packaging

Extraction

Cooling

Blockchain Traceability

Pre-Production Post Production

Seed Program

AI ControlSystem

Delivery

Intravision Greens / Software & AI

Sales & product delivery

Production Planning

Blockchain Traceability

Optimized Plant Modules

Deep Machine Learning

Production Flow (RFID tracked)

Production Environment Monitoring and Regulation

Environment Control/ Regulation

Product Safety SAP

Product Quality - shelflife

Sustainability Reporting

Soscial Resposebility / equality.....

Digitalisation

Page 27: Partnership with PlantForm Corporation MOLECULAR FACTORY

11

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11

• 130 Cannabinoler identifisert.• Svært lite forskning utført.• Nye forskninginstitusjoner under bygging i Canada.• Intravision leverer lys og forskningskammer til UoGuelph Cannabis Center.

Page 29: Partnership with PlantForm Corporation MOLECULAR FACTORY

1

INTRAVISION MedTech

Combining photobiology with controlled environent tech and atuomation...in marijuana production

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10

DevelopedBloomPhasePlants do not produce chemicals for fun! During the last weeks of the bloom phase Intravision propose light stress induced by UVA and/or UVB LED’s.

EarlyBloomPhaseThe standard approach for blooming cannabis plants is through the light/dark rythm shift from 18:6 hours to 12:12 hours. Flowering of plants are however also regulated by the red to far-red light ratio, so Intravision has included far-red light into all flower plants to assist in boosting large flowers.

VegetationPhaseThe basis for the Intravision grow-lights lies in our vegetation spectrums, which are optimized for speed of biomass production, mainly composed by red, green and either white or purple LEDs. However, the cannabis plant need a sufficiently sturdy stem to suppoert the biomass in the late stages, so a certain level of blue light needs to be included in the vegetation phase to secure optimum plant morphology development.

INTRAVISIONMEDTECH|Marijuana

Compactplantswithstrongstem,wideleavesandgoodroots.

Biggerflowers Denserbiomass,biggerflowers,increasedchrystals.

Page 31: Partnership with PlantForm Corporation MOLECULAR FACTORY

Intravision / Cannabis Approach & Technologies

The Automated FactoryIntravision has adapted the patent applied GravityFlow System towards both cannabis vegetation and Flower Rooms.

The fundament of our approach is the use of moving GrowBoxes that are being fed with nutrients in our hybrid hydroponic solution, where we keep a certain reservoir of nutrients inside each GrowBox in-between the fillings.

The flower room GrowBoxes has space for 4 large plants produced in standard 2-gallon pots that are dropped into the larger carrier.

Page 32: Partnership with PlantForm Corporation MOLECULAR FACTORY

The GRAVITYFLOW system for tall flowering plants

Page 33: Partnership with PlantForm Corporation MOLECULAR FACTORY

MIX

ROOM 10FLOWERROOM 11ROOM 12

FLOWERROOM 13FLOWER

222

210209208207

204

REPLANTINGROOM

246

230

VEG

ETA

TION

PRO

POG

ATIO

N22

9

245VEG TRAY FILLING

243

200CORRIDOR 1

AIR

LOCK 3

FLOWER FLOWERROOM 9

FLOWERROOM 8

FLOWERROOM 7

FLOWERROOM 6

FLOWERROOM 2

FLOWERROOM 3

FLOWERROOM 4

FLOWERROOM 5

MECHANICAL

ELECTRICAL

CO

RRID

OR

2

AIRLOCK 2

NUTRIENTTROLLEYPAKRING

DRYING

POSTPRODUCTION

SECURESTORAGE

STAGING

LOCK 2

AIR

CO

RRID

OR

424

1

freightelevator

drop down traysto ground

and washing

POTTING

LARGE TRAYS

SMALL TRAYS

UNI-PW250.100PALLET WASHER

UNI-PW250.100PALLET WASHER

BOXES PUT IN CORRECTPOSITION WITH LID

turning station

205IRRIGATION

206a

EQUIPMENT STORAGE206b

211 212 213 214

FLO

WER

ROO

M 1

217218219220221

MOTHER 1

MOTHER 2

MOTHER 3227

226

225

215

223

223

231

HARVEST232

237REPLANTING

235

236

WASHING

STORAGE

CO

RRID

OR

322

8

244

238

239

240b242

201

MENS WASHROOM.SHOWER AND CHANGING ROOM

205

107

107

107

107

107

107

107

107

PRODUCTION STAFFLUCH ROOM

MANAGERSOFFICE 2

MANAGERSOFFICE 3

MANAGERSOFFICE 4

MENS W.C.

OFFICIES

MANAGERSOFFICE 6

MANAGERSOFFICE 7

CONFRENCE ROOM122

STAIR 2202

216

Lifetable section of belt

PC11,1010POTTING MACHINE

2 GALLON POTSSTORAGE

Material in

Material in

GROWTH MEDIUMSTORAGE

-VEGITATION SYSTEM-

GROWTH MEDIUMSTORAGE

-FLOWERING SYSTEM-

STORAGEMEDIUM

234

STORAGEWASTE

I.T.

LUNCH ROOM

WOMENSW.C.

MANAGERSOFFICE 5

MANAGERSOFFICE

OFFICE ENTRANCE

SECURITY

107107

107

107

107

107

107

ELECT.

240a

107ENTRANCE

203

MENS WASHROOM.SHOWER AND CHANGING ROOM

Sealed and closed space between rooms

Sealed and closed space between rooms

Sealed and closed space between rooms

Sealed and closed space between rooms

Automated potting machine leading onto a conveyer belt and into the manual replanting station

planting medium brought into potting machine by overhead feed line originating in the medium storage room

Pick up area for newly planted trays ready for Flower Rooms

Manual station of putting 2 gallon pots into 2x2 trays

Auto Unloader Between Gravity Flow System andConveyer system

Area of modification

Manual transplant in station with workers on either side of conveyer belt system.Large trays moving through center and 2gallon prefilled pots moving on outer edges.

Space between Lift Shaft and structural elements left for nutrient lines

Sealed and closed space between rooms

Glass divider between harvest room and plants going out to flower roomscreating a sealed

Return conveyer belt into harvest room.Once plants have been removed from the trays, the trays can then move on to the washing room.

Per Lysaa

1:200

Drawing Description

Address

General notes

1

Ph: (+46) 0733661128© Intravision Group AS

www.intravisiongroup.com

Projection

Tolerances:Except where otherwise stated all measurement are in mm

04-sep-18

DATE

LINEAR ANGULARX +/- 0,50 X +/-0,50X,X +/- 0,20 X,X +/-0,20

Georgian Bay Biomed

Collingwood Ontario

X,XX +/- 0,10 X,XX +/- 0,10X,XXX +/- 0,05 X,XXX +/- 0,05

REV.

without written permission.

1

as the basis manufacturing or sale of apparatusbe reproduced, copied, or usedThey are issued in strict confidence and shall not

These drawings and specifications are the

Dwg. Nr.

Flow Diagram

Notes on drawing details:This drawing dose not take into consideration the most recent design changes. Only to be used as a flow diagram

Reviewed byMorgan Patterson

17-Jan-19

Issued for REVIEW

IVG-GGB-Diagram-1

Sheet

DESCRIPTION

1 of 1Scale

REVISIONS

Size

Project Title:

Reason for issue

Drawn byRevision

Updated Floor plan

Project Overview

2Project Overview

property of the Intravision Group AS

A1

17-Jan-19

Drawing name

Date

7

8 7 6 5

6

4 3 2 1

5 4

L

K

J

3

I

H

G

2 1

A

B

C

D

E

F

16 15 14

L

13

A

K

J

12

I

H

11

B

G

16

10

N

15 14

9

C

13 12 11 10

D

9

E

F

8

Page 34: Partnership with PlantForm Corporation MOLECULAR FACTORY

INTRAVISION  – Plant  factories  for  food-­‐ and  medicinal  plants

Page 35: Partnership with PlantForm Corporation MOLECULAR FACTORY

Half system seen from wall side

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View from aisle

Page 38: Partnership with PlantForm Corporation MOLECULAR FACTORY

View seen through the wall.

Page 39: Partnership with PlantForm Corporation MOLECULAR FACTORY

Intravision / Cannabis Vegetation System

The Vegetation SystemThe illustration to the left shows a 7-layer vegetation GravityFlow system designed for a 3-week cycle and 18-inch tall plants at end cycle.

The integrated LED lights system is a 2-chan-nel spectrum empowering the grower to regu-late the compactness of the plants.

Page 40: Partnership with PlantForm Corporation MOLECULAR FACTORY

Intravision / Cannabis Flower RoomThe Flower RoomT

Page 41: Partnership with PlantForm Corporation MOLECULAR FACTORY

Intravision / Cannabis Flower RoomThe Flower RoomT

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Intravision / Cannabis Flower RoomThe ”Vertical Loop”.

The 2-layer Flower Room system loops the plants vertically using automated lift systems on each side, this allows for:

(1) Access to load/ unload on ground floor.(2) Establishment of large homogeneous fields.(3) Establishment of automated plant inspec-tion systems on the re-stacking lift.(4) Stationary plant inspection / pruning sta-tion.

Intravision AURORA lights at VIVO Cannabis

GrowBoxes are looping vertically, lifted by automation and rolling down the slope.

Page 43: Partnership with PlantForm Corporation MOLECULAR FACTORY

GravityFlow System Pilot Plant, Toronto

Thank you