JUNE- 2006 (Computerized)

MICROBIOLOGY

1. Bacteria lacking catalase are sensitive to ... oxygen or superoxide ion or hydrogen peroxide?2. E coli grown in presence of DNA from a phage or something gets that DNA ----> Transformation.3. Main disadvantage of autoclave ---> dull or corrode sharp edges.4. Organism used in spore strip to check working of a sterlization unit---> Bacillus stearothermophilis (other options were all different bacilli)5. Cellulitis is commonly cause by---> Staphylococcus aureus (other things in the ques atleast were not imp. for cellutitis)6. What causes scarlet fever in S. pyogenes infection---> 7. Gas gangrene----> C. perfringens8. Food poisoning after a person eats rice stored in the fridge for a day or 2-----> B. cereus9. Conjugation ---> all are true except one kinda question.10. Burn infection ---> Pseudomonas aeruginosa11. The type of bacteria that shows an increase following eruption on primary teeth---> anaerobic???12. Periodontal infection with pus discharge ---> Actinomyces israelii13. Infection in contact wearers ----> chlamydia???14. Virus implicated in cervical cancer ----> human papilloma virus (16 & 18)15. HSV 1 stays in ---> "sensory" ganglia of trigeminal nerve (motor ganglia of trigeminal was also an option)16. HHV 8 ---> Kaposi's sarcoma17. Virus showing antigenic drifts and shifts----> Influenza virus.18. Something on Rubella (German measles)19. Retrovirus to incorporated needs---> reverse transcriptase20. Pneumonia in AIDS patients---> Pneumocystis carinii21. What is there on the surface of a B cell that binds antigen ----> Immunoglobulins22. Effect of drugs used in post transplant patient---> brings down...???23. Which one has both afferent and efferent lymphatic ducts---> lymph nodes???24. CD4 cells recognize antigen presented on ---> MHC 225. Important for opsonization ---> C3b26. Penicillins---> prevents the final step in cell wall synthesis

PATHOLOGY

1. Type of necrosis when sudden ischemia ---> coagulative necrosis2. What precedes Vasodilatation in acute inflammatory response ---> Vasocontriction3. Diagnosis of Cystic Fibrosis---> elevated Na and Cl in sweat.4. Patient has symptoms of dysphagia, some food remains accumulated in esophagus after eating etc. ----> Achalasia5. In a patient with esophageal varices ---> hemoptysis6. Malignant tumor of smooth muscles---> Leiomyosarcoma7. Location of Crohn's disease---> Colon?? ( ileum...rectum etc)8. Blood in stool, ulcers of rectum, decending colon ---> Ulcerative colitis9. HBV antigen that shows infectivity---> HBeAg10. Where are fats stored in fatty liver---> inside the liver cells11 Patient dies 24 hrs after a MI , biopsy would show ---> myocardial necrosis + inflammatory cells ???12. Which of the following might be a cause of hypertension ---> pheocromocytoma13. Childhood malignant tumor ---> Neuroblastoma / wilms tumor (both options were there... dont rem the ques well)14. Patient with hypercalcemia---> primary hyperparathyroidism15. Calcification in Atherosclerotic plaque ---> dystrophic calcification ???16. Cells present in granulomatous inflammtion---> monocyte/macrophage with lymphocytes???17. Role of vit. K in clotting?18. Leukemia in childhood---> Acute lymphocytic leukemia19. Child with enlarged skull bones n long bones with increased alkaline phoshatase ----> pagets disease 20. Iron is tranported in blood in the form of ---> Transferrin21. chylomicron etc

BIOCHEMISTRY/PHYSIOLOGY

1. In Henderson-Hasselbalch equation pH=PKa when---> conjugate acid = conjugate base2. pH was given, was asked to find out concentration of [H+]3. An inhibtor binds to the enzyme at the active site this inhibitor---> can be overcome by increasing the substrate4. Site of beta oxidation or something 5. question based on site of electron transport chan6. Bond between the base and sugar in a nucleotide---> glycosidic???7. chromosome number at telophase of mitosis in a human cell8. Location of parietal cells or something in stomach9. B.P. = Cardiac Output * total peripheral resistance (confirm this)10. Acidic hormone or anterior pitutary---> GH (Prolactin was not an option)11. some effect of glucagon thru cAMP12. In what case does the gas diffusion decreases ---> when the membrane thickness increases13. What receptors are stimulated in Hering Breuer reflex ---> stretch receptors in the lungs14. Patient with dettachment of retina on left eye, response of his pupil to bright light15. All the capillary and interstitial pressures were given, was asked to calculate the net flow.16. Where in small intestine are the crypts of Lieberkuhn located---> epithelium ?? other options were submucosa, muscularis...etc