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About Dr. Neal Rouzier

Neal Rouzier, M.D.Seminar Instructor

Dr. Rouzier specializes in bioidentical hormone replacement for men and women. He is the Director of The Preventive Medicine Clinics of the Desert, specializing in the medical management of aging and preventive medicine. His passion for literature research has led him to be one of the most credible speakers in this field. The basis for this course is an extensive review of evidence-based medicine that should serve as a reference source, and direct the practitioner in determining the best methods for hormone replacement. The scientific standard should be the standard when it comes to prescribing bioidentical hormones.

About the CouRseFor those familiar with Dr. Rouzier’s style and presentation, these seminars are designed to pack an inordinate amount of practical information into a motivating 2 or 3 day experience. His courses can be described in several ways. They are a literature review demonstrating the health benefits and physiology of hormones, the detrimental effects of hormone deprivation and the importance of hormone replacement. More importantly, the literature review demonstrates that there is a difference in types of hormones and that synthetic ≠ bioidentical. Finally, and most importantly, in every study the literature supports that normal levels ≠ optimal levels, which is of utmost importance when monitoring and adjusting hormones for optimal health and well-being.

Dr. Rouzier, trained in Family Practice and Emergency Medicine, is recognized as a renowned leader and expert in the field of bioidentical hormone replacement. He has over 16 years of experience as an educator and practicing physician. His professional knowledge and teaching excellence are reflected in the popularity of his courses. It is Dr. Rouzier’s goal in these workshops to share his experience, expertise and techniques. You will improve diagnostic skills, intensify preventive approaches, provide more comprehensive services and enhance your practice style. Increased knowledge of the field will result in increased quality of care and patient satisfaction. Adding preventive medicine will promote a more effective and satisfying medical practice. Following seminar attendance, Dr. Rouzier will remain available in the future to assist you with any questions to ensure your success. His courses build on one another and should be attended in order of Part I, Part II and finally Part III. Inside this 2011 seminar brochure, you’ll find the course description, educational goals and agenda for each of the three courses, followed by other pertinent event details such as dates, location and accommodations.

Who should consider attending this seminar? Any healthcare professional working within the medical community who is interested in understanding the preventive medicine and quality of life issues, and the safe use of hormones in the medical management of aging.

This overview will hopefully stimulate your interest as you begin to explore the notion of healthy aging. Natural hormones are pharmaceutical, bio identical (human identical) hormones derived from plants and synthetically manufactured. This course provides all the nuts and bolts of prescribing, monitoring, adjusting and troubleshooting.

sPeCIAL NotICe:New three-day agenda for Part I and Part II.

See page 14 for details.

P: 888-222-2966 www.worldlinkmedical.com

“ It is probably the most gratifying thing I’ve done in my entire career.”Randy Birken, MD

“ This one out does others in all ways: cost, location, utility, and practicality.”Sadhana Kamath, MD“

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• Provides the essential clinical protocols to treat patients with bioidentical hormones.• Enhances Physician and Practitioner knowledge of nutrition, fitness, and overall preventive health• Past course graduates can expect to be updated on the most recent medical studies and protocols to maintain best treatment practices.

THE BENEFITS

• Evidence-based. Over 50 years of medical literature to support unique patient protocols.• Practical. Right away, Physicians and Practitioners can learn the ‘ins-and-outs’ of bio identical hormone therapy and implement it into their practice.• Valuable. Graduates continue to report a higher return on investment compared to alternative conferences.

• You are seeking a preventive, proactive approach to medicine. • You want to increase a meaningful and productive relationship with your patients by helping them restore their physical, emotional, and sexual well-being. • You are looking for a CME course that provides information you can successfully incorporate into your medical practice.

THE DIFFERENCE

YOU SHOULD ATTEND IF

oPtIMIZAtIoN oF heALth thRouGh oPtIMIZAtIoN oF hoRMoNes:A Literature Review Demonstrating that Synthetic HRT ≠ Bioidentical HRT

Clinical studies have demonstrated that DHEA has a beneficial effect on immune response, sex drive, metabolism and emotional stability. DHEA benefits the immune system and reduces visceral fat associated with diabetes mellitus. Other health-related benefits include support of cognitive function, helping the body cope with stress, and protection against heart disease through its effects on lipids and body fat.

DHEA

Melatonin regulates the circadian rhythm as well as the deep stages of sleep. Studies suggest that the immune system depends on melatonin’s effects of deep sleep. In the January 1997 issue of the New England Journal of Medicine, melatonin was demonstrated to be a powerful antioxidant hormone that can protect against cancer. There are hundreds of studies showing that melatonin can scavenge free radicals, and be a safe sleep-enhancing hormone.

MELATONIN

Over 50 years of studies demonstrate that loss of estrogen increases cardiovascular disease, Alzheimer’s Disease, osteoporotic fractures, urogenital atrophy, macular degeneration and depression. Recent studies sort out the confusion created by the WHI (Women’s Health Initiative) and conclude that certain types of hormones cause harm in some women, whereas different hormones avoid the harm and provide significant protection. A thorough literature review helps sort out the differences and provides credence and confidence for the use of bioidentical estrogens as based on our medical evidence.

ESTROGEN

Although testosterone is the primary male hormone, women also benefit from its supplementation. Levels of testosterone decline with age in men and women. At optimal levels, research shows testosterone increases bone density and bone formation, enhances energy and sex drive, decreases body fat, increases muscle strength, lowers blood pressure and modulates cholesterol levels. Testosterone is a hormone that neither men nor women should be without and we’ll present the scientific evidence to support this.

TESTOSTERONE

This metabolic hormone secreted by the thyroid gland regulates temperature, metabolism and cerebral function. Insufficient thyroid levels result in fatigue, increased cholesterol levels and increased risk of coronary artery disease. With age, thyroid hormone levels gradually decline resulting in a decreased metabolism, which affects all cells and organs. Low thyroid causes low energy, and thinning of hair, skin and nails. The dictum that normal levels are not optimal levels is extremely important when it comes to thyroid.

THYROID

Failure of memory and lack of mental clarity can be among the most frustrating aspects of aging. Studies indicate that pregnenolone might be beneficial against age-related cognitive decline.

PREGNENOLONE

oPtIMIZAtIoN oF heALth thRouGh oPtIMIZAtIoN oF hoRMoNes:A Literature Review Demonstrating that Synthetic HRT ≠ Bioidentical HRT

PROGESTERONEData demonstrates that synthetic progestins increase the risk of breast cancer, heart disease, strokes, bleeding and depression. Studies demonstrate that not only does micronized progesterone not increase these risks, but it also protects against them. Studies demonstrate a synergistic effect of progesterone with estrogen, whereas progestins negate estrogen’s positive benefits. This literature review will demonstrate the difference between progesterone and progestins and how this difference is the key to understanding the importance of progesterone.



Upon completion of this workshop, the healthcare professional will be able to:

1. Describe how to effectively educate your local community on the health benefits of proper nutrition, exercise, and better personal health choices. 2. Demonstrate an understanding of the behavioral indicators that impact patient compliance. 3. Apply the clinical techniques that increase compliance, resulting in improved patient care. 4. Develop individual elements into a successful wellness program based on medical specialty, strengths, and the needs of the local community. 5. Identify a process that has been used to accomplish specific community healthcare goals. 6. Evaluate the qualifications of support staff to maximize a successful wellness program.7. Create synergistic partnerships to support and sustain change. 8. Identify the limitations of conventional allopathic practice in addition to the breadth and therapeutic potency of an integrated approach, including: hormone analysis and balancing for maximum therapeutic potency in service and devotion to the patient.9. Apply a graduated approach to practice transition by identifying the balance between hormone replacement and mental focus, while maintaining the conventional portion of your practice. 10. Identify the financial factors which are impeding physicians from delivering maximally efficient and therapeutic care and how to deal with them.11. Discuss current literature on the role of thyroid, adrenal, and sex hormones as they pertain to conditions thought to be “psychiatric” or “mental health” areas of concern.12. Demonstrate the concept of “stabilizing the biological platform” in mental health. Learn how to stop blaming or stigmatizing the patient when depression and mental disorders do not seem to be responding to conventional treatment. 13. Demonstrate an understanding of aggressive psychopharmacology, as well as dealing with the need for use of emergency psychotropics in conventional medical practice.14. Understand, quickly grasp, and expertly diagnose and treat with straightforward psychotropics, as needed.15. Evaluate and become proficient in the medical literature that supports biologically identical hormone replacement in contrast to chemically altered hormones and realize that “all hormones are not the same” as demonstrated in the literature.16. Describe the diagnosis and treatment of adult onset growth hormone deficiency.17. Identify the techniques used to administer acceptable levels of human growth hormone (HGH).18. Examine and discuss possible side effects of HGH and how to properly adjust dosing.19. Distinguish the different types of secretagogues and evaluate their effectiveness as an alternative to HGH therapy.20. Implement therapeutic management of andropause based on studies reported in prestigious medical journals.21. Identify the types, doses and methods to administer testosterone to men and women.22. Determine the uses of testosterone for men and women, including complications, precautions, side effects and monitoring.23. Discuss the uses of Finasteride, Dutasteride, Anastrozole in the management of testosterone administration.24. Identify the uses of melatonin including correct dosing and monitoring.25. Apply strategies for the effective uses of DHEA and pregnenolone including correct dosing and monitoring.26. Evaluate new evidence that contradicts the WHI Study on estrogen treatment in women.27. Demonstrate an understanding of the health benefits of estrogen and progesterone in contrast to the health detriments of synthetic estrogen and progestin.28. Describe the types, doses and methods used to administer estrogen and progesterone.29. Discuss recent literature, questions and answers that demonstrate the beneficial effects of hormones in improved function and healing and a better quality of life.30. Explain current concepts of thyroid replacement and compare and contrast different types of thyroid as supported in the medical literature.31. Recognize various methods of testing for thyroid deficiencies and what labs and approaches are best.32. Discuss and analyze interesting cases in bio identical hormone replacement therapy.33. Recognize the difference between “normal levels” and “optimal levels” of hormones and the benefits or detriments as demonstrated by current medical studies.34. Implement best clinical practices in diagnosing, prescribing, monitoring and adjusting of BHRT for improved function and quality of life.35. Develop and apply business management principles to set up a preventive medicine practice.36. Analyze and review treatment protocols in case management and troubleshooting techniques used in BHRT.

WorldlInk MEdIcAl SEMInAr SErIES PArt IOptimal Hormone Replacement = The Best Preventive Medicine

22.5 AMA PRA Category 1 Credits, 22.5 Nursing Contact Hours, 22.5 Pharmacy CE

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SEMInAr SErIES PArt I - obJEctIVES contInuEd:

CouRse DesCRIPtIoN: Part One is a workshop utilizing a case study approach designed to help physicians successfully and knowledgeably treat their age management patients. Friday’s sessions will focus primarily on how to implement a successful nutrition and fitness program into practice, with a strong focus on patient behavioral change. From there we will explore hormone replacement from a Psychiatric point of view and how to transition to an integrated medical practice. Then, in two information-jammed, technique-packed days you’ll get the real nuts and bolts of hormone replacement therapy. You’ll learn about monitoring and troubleshooting HRT through literature presentations, case studies and open discussions. Your practice of natural hormone replacement therapy will be based on peer-reviewed medical research and a wealth of clinical experience. This is the most comprehensive course taught on this subject, designed to give you practical information and skills that you can use on a daily basis. The curriculum is an evidence-based program on preventive medicine designed to enhance your diagnostic and prescribing skills when optimizing hormones for both men and women.

FRIDAyFRIDAy MoRNINGTimothy McKnight, M.D.

7:30 – 8:00 a.m. – RegistRation

8:00 – 9:00 a.m.motivating YouR CommunitY to BeCome Fit FoR LiFe

• Overview of a successful wellness program• Results of a successful wellness program• Lessons learned

- What the participants (critiques) have taught us- What the results have taught us

9:00 – 10:00 a.m.inFLuenCing BehavioRaL Change FoR Positive outComes

• Altering Behavior Chemistry: the Mind-Body Connection

-How we learn-How we re-program behavior

• Mind-Body awareness techniques- Meditation Exercise- Eating Exercise- Body Balance exercise- Forming new habits exercise (signing name)- Get outside the box exercise (9 dots puzzle)- Perception exercises- Neurolinguistic programming

10:00 – 10:15 a.m. – BReak

SEMInAr SErIES PArt I - AgEndA:

37. Describe how to write prescriptions for compounded hormones to pharmacies, and how different formulations can affect absorption, efficacy and side effects.38. Correct any inaccurate or inappropriately prescribed hormone therapy to conform to scientific standards as seen in medical literature.39. Implement current strategies into your practice to improve the level of care and patient compliance in the treatment of adult hormone deficiencies.40. Assure that prescribed hormones meet standards of care based on attaining adequate serum levels and symptom improvement.

10:15 – 11:15 a.m.FoRmuLating a PRomising WeLLness PRogRam

• Plan, Execute, Evaluate, Revise• Key ingredients to being successful in wellness

- Educate, motivate, inspire, change- Learning from AA and other treatment

programs• How to help patients ask the right questions

about healing- Start asking the right questions (examples of

“wrong” and “right” questions)• Individualizing Your Wellness Program

- Your Personal Belief Systems – Exercises• Formulating your own Program

- Begin with the End in Mind- Know your strengths, weaknesses, resources,

partnerships

11:15 a.m. – 12:00 P.m.CoLLaBoRating to enhanCe Change

• The power of collaboration/teamwork • Partnering within your program • Partnering within your community

12:00 – 2:30 P.m. – LunCh BReak

non-Cme Compounding Pharmacy Tour to include lunch and Business Development sessions. Transportation to and from the Hilton Garden Inn will be arranged.

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SEMInAr SErIES PArt I - AgEndA contInuEd:

FRIDAy AFteRNooNLouis Cady, M.D.

2:30 – 3:15 P.m. hoW to tRansition FRom a tRaditionaL aLLoPathiC PRaCtiCe to a hoListiC and integRated mediCaL PRaCtiCe

3:15 – 4:00 P.m.mentaL heaLth and hoRmones: What in the WoRLd do hoRmones have to do With CuRRent aLLoPathiC PsYChiatRY?

4:00 – 4:30 – BReak

4:30 – 5:15 P.m.“PetaL to the metaL” aLLoPathiC PsYChiatRY FoR geneRaLists

• Your patients are on HRT but their mental health issues persist - What to do next?

sAtuRDAyNeal Rouzier, M.D.8:00 – 9:00 a.m.intRoduCtion to hoRmone RePLaCement theRaPY

• Importance of optimization of all hormones as per the medical literature

• Health and quality of life benefits• The best preventive medicine to maintain well-

being and reduce morbidity & mortality• Normal is not optimal; and optimal is best• Examples of optimal labs vs. normal labs• HRT replacement: Have we been doing it

incorrectly all this time?• What we should know about hormones but were

never taught• Why we do what we do based on the medical literature

9:00 – 10:00 a.m.human gRoWth hoRmone = human heaLing hoRmone

• HGH: What doesn’t it do? It does everything good

• A literature review demonstrating improvement in health & well-being

• The safest hormone without side effects when administered correctly• Prescribing, monitoring, adjusting, documenting

for HGH• Which test is best: growth hormone levels, ITT,

IGF-1, IGF-PB3

10:00 – 10:15 a.m. – BReak

10:15 a.m. – 12:00 P.m.testosteRone: saFe and neCessaRY FoR Both men and Women

• Various types are available but which is best• Applications: How, where, when, and why to

apply• Complications, precautions, side effects and

monitoring• What levels are normal and what levels are

optimal • PSA, free PSA, and prostate cancer• DHT, Estradiol, Finasteride, Anastrazole,

5α-reductase inhibitors, & aromatase inhibitors• A literature review

testosteRone FoR Women: the FeeL-good hoRmone FoR Women too

• It is not just a male hormone• What types, doses and levels work best• Application: How, where, when, why to apply • Side effects and treatment with Spironolactone• Extensive literature review

12:00 – 1:00 P.m. – LunCh BReak

1:00 – 2:00 P.m. meLatonin, dhea and PRegnenoLone: aLL hoRmones PRovide heaLth BeneFits

• Melatonin: The great sleep and immune enhancer• Treatment & prevention for cancer, HTN,

migraines• Administration & monitoring: How much is

enough?• DHEA: How DHEA improves health and

longevity• DHEA: How to prescribe, monitor, and adjust

for maximum benefit• A literature review supporting optimal levels• Side effects and use of spironolactone• Pregnenolone: The mother of all sex hormones• Memory enhancer? And what about cancer?• A literature review of these hormones• Administration, monitoring and adjusting

2:00 – 3:45 P.m.menoPause: estRogen & PRogesteRone aRe aBsoLuteLY neCessaRY FoR heaLth & WeLL-Being

• Natural vs. synthetic; Risk vs. benefit – a literature review of types of estrogens

• Health benefits and feel-good benefits of HRT• Don’t fear it: The most recent consensus views• Informed consent for stopping HRT and harm of

hormone deprivation• What types of estrogen: How, what, where, why?

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SEMInAr SErIES PArt I - AgEndA contInuEd:


• ACOG and NAMS: no study to show efficacy of BHRT wrong!

• Doses, monitoring levels, adjusting, selection: What works best and when

• The importance of serum monitoring• Transdermal vs. oral: Benefits and harm of each• Does age make a difference?• Indication and contraindications: Problems with

synthetic vs. bioidentical vs.compounded• New evidence that contradicts the conclusions of the

WHI Trial.• Different strategies for managing PMS, Peri-

menopause, and MenopausePRogesteRone: Just as imPoRtant as estRogen

• Absolutely necessary in all women at whatever age• A literature review: There is not one negative study• Protection against breast cancer, uterine cancer, heart

disease• MP ≠ MPA, natural vs. synthetic, good vs. harmful• If some is good, more is better? Absolutely• Dosing, monitoring, adjusting, and the importance

of optimization• Serum vs. saliva testing and harm of progesterone

deprivationComPounded BhRt: the good, the Bad, and the ugLY

• From worthless to lifesaving: It all depends on quality and dosing

3:45 P.m. – 4:00 P.m. – BReak

4:00 – 5:30 P.m.thYRoid: WhY Patients demand it

• The most misunderstood and ignored hormone• Thyroid test is normal, so what?• Types of hypothyroidism• Does your patient need their thyroid to be optimal?

You bet! • Understanding lab values• What is responsible for low thyroid symptoms when

TSH is normal?• Types of thyroid hormones, dosing, monitoring,

adjusting• Treatment of fatigue: TSH or Free T3?• Endocrine viewpoint (labs) vs. patient perspective

(symptoms)• Signs and symptoms of sub-optimal thyroid

replacement and treatment• Literature support for optimization: Treat the labs

or the patient?• Improvement of health and well-being through

optimization

5:30 – 6:30 P.m.summaRY & RevieW

• Interesting cases• HRT indications, contra-indications, risks,

benefits• Side effects, problems, complications• Dosing & adjustment of various types available

with lab reference comparisons• Cautions, suggestions, things to do, and mistakes

to avoid

suNDAy8:00 – 9:45 a.m.Case management: eveRYthing You shouLd knoW

• The nuts & bolts for practicing HRT correctly• Administration and appropriate dosing• Monitoring the patient and adjustment

9:45 P.m. – 10:00 a.m. – BReak

10:00 a.m. – 12:00 P.m.Case management: eveRYthing You shouLd knoW

• Proper case management, problems and complications

• Mistakes to avoid• Lab interpretation & lab comparisons• Different optimal levels for different laboratories

12:00 – 1:00 P.m. – WoRking LunCh BReak

sPeCiaL guest sPeakeR, CaRoLYn RouzieR: “setting uP mY PReventive mediCine PRaCtiCe: What WoRks and What doesn’t”

• Outline, worksheet, forms, letters and consents• How to bill• Different types of programs• Necessary equipment• Evaluating pharmacies and laboratories• Products and services

1:00 – 2:00 P.m.RevieW oF PRaCtiCaL aPPLiCation

• More treatment protocols• Maintaining scientific standards• Troubleshooting and case management• Complicated cases: See if you get them correct

2:00 - 3:15 P.m.100 Written Questions and Answers with Discussion3:15 P.m. – WRaP-uP/ evaLuation/ adJouRnment

• Lessons learned

due to the fast paced nature of the course, Parts I and II must be com-pleted before attending Part III.

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23.5 AMA PRA Category 1 Credits, 23.5 Nursing Contact Hours, 23.5 Pharmacy CE WorldlInk MEdIcAl SEMInAr SErIES PArt II

Optimal Hormone Replacement Means Maintaining and Assuring Serum Levels that are Optimal, Based on Proven Scientific Protocols

Upon completion of this workshop, the healthcare professional will be able to:

1. Discuss the concept of a practical biomarker of physiological aging in the context of the National Institute on Aging’s claim that there are as of yet no validated biomarkers of aging.2. Identify five biomarkers of aging which, when combined, result in an informative overall picture of a patient’s aging process.3. Demonstrate the preventive health benefits of maintaining good intestinal flora.4. Describe the various clinical disorders that are caused by a lack of probiotics and how to treat them.5. Determine the structure and function of human telomeres and telomerase.6. Discuss the literature demonstrating the strong association between telomere length and aging/chronic disease risk.7. Examine clinically available methods for telomere length measurement (qPCR, Flow-FISH, and STELA for short telomeres).8. Evaluate the currently available ways to slow telomere shortening through diet, exercise, stress reduction, antioxidants, BHRT, and small-molecule telomerase activation.9. Outline key elements in HRT presented in Part One: Mastering the Protocols for Optimization of Hormone Replacement Therapy.10. Identify important issues in the relationship between hormones and cancer: cause, provocation or protection?11. Outline problem-solving techniques for difficult cases presenting with multiple disease processes and the potential benefits of hormones.12. Discuss literature citing new indications, risks, benefits and complications of estrogen, progesterone and testosterone therapy.13. Determine advanced treatment modalities and dosing strategies for estrogen and progesterone, including new and specific approaches to these therapies. 14. Describe important aspects of the WHI findings: identify the experts that refute this study, and other factors not included in the trials that would change the conclusions.15. Determine advanced treatment modalities, including new and specific approaches to HGH, thyroid and testosterone in age management and disease prevention. 16. Discuss over 40 articles that demonstrate thyroid replacement does not cause osteoporosis, even in TSH suppressive doses.17. Identify various new therapies for erectile/sexual dysfunction in men and women.18. Evaluate the epidemiology of cardiovascular disease and diabetes and the various treatment strategies as they pertain to medication, diet, exercise, lifestyle change and nutritional supplements.19. Explore the role of omega 3 fatty acids, antioxidants and glucose and their influence on insulin, inflammation, disease progression and atherosclerosis.20. Describe the strategies for using the new cardiovascular risk markers, inflammation markers, new lipid parameters and how to make sense of all the new lipid fractionation components.21. Identify the roles of niacin and EFA in diabetes and atherosclerosis.22. Identify rational approaches to vitamins and supplements with a review of the medical literature supporting their use in wellness as well as citing any harmful effects and interactions.23. Determine current screening methods and management strategies of the most common pre-menopausal hormone disorder, Polycystic Ovary Syndrome (PCOS).24. Implement diagnostic and treatment strategies for PCOS.25. Apply diagnostic and treatment strategies for hirsutism and hair loss.26. Implement strategies for treating osteoporosis using hormone replacement therapy.27. Discuss interesting cases in bio identical hormone replacement therapy.28. Identify current indications, risks and benefits of using cortisol for the treatment of chronic fatigue. 29. Determine rational approaches for the evaluation of fatigue with emphasis on cellular hypofunction as it pertains to thyroid hormone.30. Describe, based on the literature, when to use oral vs. saliva testing.31. Utilize the knowledge gained to improve patient outcomes in BHRT.

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CouRse DesCRIPtIoN: Part Two follows the Part One series with advanced concepts and up-to-date research. Due to the fast-paced nature of the course, This three-day seminar will keep you current on the appropriate skills needed to manage everyday problems. It will serve as a short refresher, including important new therapies, clinical pearls, tricks of the trade, advanced techniques and difficult case management sessions. Additionally, the Friday session will focus on the role of Probiotics, Nutritional Supplements and Telomeres in preventing and treating the common diseases of aging. The field of age management medicine continues to grow at a rapid rate, mak-ing it difficult to stay abreast of all the changes. Included in Part Two is an hour-long lecture that reviews the scientific literature giving credence for this type of practice. Over 200 peer-reviewed articles, the foundation for Dr. Rouzier’s advanced course, will be provided as a reference for the participant. This is the same lecture Dr. Rouzier gives to medical academies to inform physicians of the health benefits of age management therapies.

due to the fast paced nature of the course, Part I must be completed before attending Part II.

FRIDAyFRidaY moRning

7:30 – 8:00 a.m. – RegistRation

8:00 – 9:00 a.m.BiomaRkeRs oF aging: essentiaL tooLs FoR the next geneRation age management PhYsiCian

Joseph Raffaele, MD

9:00 – 10:00 a.m.a gut CheCk on Patient CaRe: the RoLe oF PRoBiotiCs in PReventive heaLth

Vaughn Johnson, D.o.

10:00 – 10:30 a.m. – BReak

10:30 – 11:30 a.m.teLomeRe taLk: What the PRaCtiCing PhYsiCian needs to knoW in 2012Joseph Raffaele, M.D.

11:30 – 2:30 P.m. – LunCh BReak

non-Cme ComPounding PhaRmaCY touR to inCLude LunCh and Business deveLoPment sessions. tRansPoRtation to and FRom the hiLton gaRden inn WiLL Be aRRanged.

2:30 – 3:00 P.m. – RetuRn to the hiLton gaRden inn

FRIDAy AFteRNooNneal RouzieR, M.D.

3:00 – 6:00 P.M.age management RevieW

• Literature review of hormones• Cancer and hormones, HGH, Testosterone,

Estrogen and Progesterone• New studies refute the WHI mistakes

6:00 – 8:00 P.M. (NoN-CMe)

inFoRmaL Question and ansWeR PeRiod

• Difficult cases• Open discussion

sAtuRDAy8:00 – 10:00 a.m.advanCed sCientiFiC RevieW

• Estrogen • Progesterone• New evidence contradicting the WHI Trials• Transdermal vs. Oral: the debate continues

10:00 – 12:00 noonadvanCed sCientiFiC RevieW, Cont.

• HGH• Thyroid• Testosterone

12:00 – 1:00 P.m. – LunChBReak

1:00 – 2:00 P.m.diaBetes

• Insulin resistance• EPA’s• Benefits of exercise

2:00 – 4:00 P.m.CaRdioLogY

• Preventive therapy markers• Niacin• Cases studies

4:00 – 6:00 P.m.vitamins and suPPLements

SEMInAr SErIES PArt II - AgEndA:

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SEMInAr SErIES PArt II - AgEndA contInuEd:

suNDAy8:00 – 9:00 a.m.PoLYCYstiC ovaRY sYndRome

9:00 – 10:00 a.m.hiRsutism and haiR Loss in men and Women

10:00 – 11:00 A.M.osteoPoRosis

• Estrogen metabolites• NTX

11:00 – 12:00 noon

inteResting Cases

12:00 – 1:00 P.m. – LunCh BReak

1:00 – 2:00 P.m.ChRoniC Fatigue and oPtimaL tReatment modaLities

• Cortisol• Thyroid

2:00 – 3:00 P.m. test YouR knoWLedge - RevieW

• 100 questions with answers and discussion


“Excellent – very knowledgeable and motivating, and willing to answer questions at any time!”

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CouRse desCRiPtion: The educational process for Part III is both didactic and interactive with maximum audience participation. All of the most complex, interesting, and confusing cases experienced by Dr. Rouzier over the last ten years are presented. The participants decide on the corrective management. Although there are no medical boards for this type of practice, Part III is similar to a medical board that digs deeper into the complexities of age management medicine. Clinical cases will be analyzed to formulate appropriate treatments and management to improve the understanding and level of care provided to patients. The Part I cases and studies are simple and straightforward. However, a thorough understanding of Parts I and II are necessary to understand many of the scientific papers presented in Part III. Studies are presented that demonstrate more harm and cancer caused by regular, standard treatments for cholesterol than by PremPro®. Progesterone causes decreased absorption of estrogen yet it can be prevented. Most patients have very low Vitamin D levels (which are harmful), yet most doctors don’t know how to optimally treat and monitor. Differentiation between adrenal hyperplasia and PCOS is important, as well as understanding treatment of thin women vs. obese women. It is also important to understand when women require transdermal vs. oral estrogen. The risk of prostate cancer decreases for every doubling of estradiol level or SHBG. Finally, estrogen’s effect on lipids and SHBG are what is most protective against CVD. Each of these topics will be thoroughly addressed.

due to the fast paced nature of the course, Parts I and II must be completed before attending Part III.

Upon completion of this workshop, the healthcare professional will be able to: 1. Outline key elements in age management presented in Part Two: Mastering the Protocols for Optimization of Hormone Replacement Therapy, per relevant literature and case studies.2. Discuss the most current literature for bio identical hormone replacement therapy (BHRT), Human Growth Hormone (HGH), thyroid, testosterone, pregnenolone, Dehydroepiandrosterone (DHEA), melatonin, estrogen and progesterone.3. Determine the risks and benefits of transdermal estrogen vs. oral estrogen.4. Discuss new research demonstrating estrogen’s protective effects in men as well as lack of any harm.5. Examine current recommendations for hormone replacement therapy by the North American Menopause Society (NAMS) and American College of Obstetricians and Gynecologists (ACOG). 6. Describe rational approaches to the use of hormones in cancer patients, including recent studies that demon strate progesterone’s protection against breast cancer and the adverse effects of progestins. 7. Discuss new therapies for prostate cancer as well as better diagnostic sensitivity and specificity of MRI-S scan.8. Determine current management strategies for preventing loss of pregnancy in Polysystic Ovary Syndrome (PCOS), as well as preventing and treating postpartum depression.9. Describe the clinical evaluation including laboratory analysis and treatment of Vitamin D deficiency. 10. Examine literature reviews as to what level of Vitamin D protects against cancer, CAD, osteoporosis, dementia, type II DM and AMD.11. Discuss the pathophysiology of vaginal atrophy and the use of rings, tabs, troches and creams.12. Discuss the importance of sex hormone binding globulin (SHBG) in men and women and why it is most predictive of CAD, MS and cancer. 13. Describe the data demonstrating that androgen suppression therapy, as well as estrogen deprivation, is associated with poor survival in men in comparison with placebo.14. Outline advanced treatment protocols for over 100 clinical cases based on clinical presentation, history and complications.15. Discuss the inverse relationship of estrogen and prostate cancer.16. Develop an understanding of treatment rationale through case presentations.17. Appreciate the lack of efficacy of estriol in spite of purported benefits.18. Review the recent recommendations from Family Practice Recertification on the use of IGF-1 instead of the ITT to diagnosis GH deficiency.19. Discuss recent studies demonstrating IGFBP-3 induces apoptosis in prostate cancer and breast cancer. 20. Review the antiproliferative, oncostatic, immuno-stimulatory and thrombopoetic effects of melatonin.21. Describe the difference in clotting between Premarin®, Provera® and micronized progesterone.22. Examine data proving that oral progesterone decreases clotting risk and inflammation as opposed to Provera® that increases these risks.23. Appreciate the data demonstrating that only certain types of estrogen reduce fatty acid synthesis thereby resulting in a protection against atherosclerosis.24. Demonstrate an understanding of the importance of maintaining low levels of aldosterone.25. Demonstrate an understanding of the importance of body weight in determining which type of HRT to prescribe. 26. Describe the data demonstrating that testosterone both decreases and increases CAD in women and learn to decipher the correct approach. 27. Identify the two mechanisms by which estrogen treats and protects against prostate cancer.

15.0 AMA PRA Category 1 Credits, 15.0 Nursing Contact Hours, 15.0 Pharmacy CE WorldlInk MEdIcAl SEMInAr SErIES PArt III

Evidence-Based Medicine


sAtuRDAy7:30 – 8:00 a.m. – RegistRation

8:00 – 9:00 a.m.intRoduCtion and RevieW

• Compounded hormones and estriol: does the science support the claims?

• Saliva testing• Bioidentical hormone review• Recent relevant literature review

9:00 – 10:00 a.m.thYRoid and testosteRone

• Thyroid T3 use in depression, functional hypothyroidism and prevention of CAD

• Thyroid does not cause osteoporosis• Testosterone use after prostate cancer• Different testosterone therapies have different

effects on lipids, blood levels and side effects

10:00 – 11:00 a.m. 200 Case studies With Q & a

11:00 – 12:00 noonhuman gRoWth hoRmone

• New articles for off-label use• How to diagnose and treat deficiency• HGH and cancer: a review of the world data• New articles to support safety

12:00 – 1:00 P.m.- LunCh BReak

1:00 – 2:00 P.m. hoRmone LiteRatuRe RevieW • Estrogen’s role in men for osteoporosis, CAD and prostate cancer

2:00 – 3:00 P.m.200 Case studies With Q & a, Cont.

3:00 – 4:00 P.m.PCos: What the Books don’t teLL You • How to handle tough PCOS cases • Aldosterone: it must be treated • Diagnosis and treatment of adrenal hyperplasia • Focus on the vagina: the various ways to treat it

4:00 – 5:00 P.m.PRogesteRone and PostPaRtum dePRessionhoW to Raise and LoWeR shBg: When and WhYshBg and Cad, dm and htn 5:00 – 6:00 P.m.Question and ansWeR time

suNDAy8:00 – 9:00 a.m.200 Case studies and PResentations, Cont.

9:00 – 10:00 a.m.vitamin d • Diagnosing, prescribing, monitoring and adjusting • A literature review • A lab review

10:00 – 11:00 a.m.the antiPRoLiFeRative, onCostatiC, immune stimuLatoRY and thRomBoPoetiC eFFeCts oF hRt

11:00 – 12:00 noonestRogen • Oral vs. transdermal: which is best and why • Hormones and clotting

12:00 – 1:00 P.m. – LunCh BReak

1:00 – 2:00 P.m.mmP, CLotting FaCtoRs, inFLammatoRY PRoteins and FattY aCid esteRs in Cvd

2:00 – 3:00 P.m.andRogen dePRivation theRaPY: hoW to PRevent the inCReased moRtaLitY, Cad and dm side eFFeCts200 Case studies With Q & a, Cont.

3:00 P.m. – WRaP-uP / evaLuation / adJouRnment


SEMInAr SErIES PArt III - AgEndA:

13

Premarin® and PremPro® are the registered trademarks of Wyeth Pharmaceuticals Inc.Provera® is the registered trademark of Pfizer Inc.

Telomere Talk and Biomarkers of Aging: What the Practicing Physician Needs to Know in 2012.Joseph Raffaele, M.D.


neW FoR PaRt i – On Friday, we’ll focus primarily on how to implement a successful nutrition and fitness program into practice, with a strong focuss on behavioral change. From there we will explore hormone replacement from a Pyschyatric point of view and how to transition to an integrated medical practice.

AMA PrA cAtEgory 1 crEdIt StAtEMEnt

Jointly sponsored by the Foundation for Care Management and WorldLink Medical.

MedQuest Pharmacy provided in-kind support for this workshop.

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Foundation for Care Management (FCM) and WorldLink Medical. FCM is accredited by the ACCME to provide continuing medical education for physicians.

FCM designates this educational activity for a maximum of 22.5 (Part I), 23.5 (Part II) and 15.0 (Part III) AMA PRA Category 1 creditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

nuRsing CRedit statement

The Foundation for Care Management is an approved provider of continuing nursing education by the Colorado Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. Approval Period: July 1, 2009 - June 30, 2012. Provider #FCM-0612.

PhaRmaCY CRedit statement

The Foundation for Care Management is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

Part I Program #0347-9999-12-001-L01-P. *This CE is knowledge based (K). Initial release January 27-29, 2012.

Part II Program #0347-9999-10-002-L01-P. *This CE is knowledge based (K). Initial release May 11-13, 2012.

Part III Program #0347-9999-10-003-L01-P. *This CE is knowledge based (K). Initial release October 19-21, 2012.

The Part I and Part II courses are now three-day events, featuring additional lectures designed to help you expand and grow your practice.

nEW for 2012

Changing Patient Behavior to be Fit for Life:Successfully Implement Nutrition and WellnessTimothy McKnight, M.D.

Mental Health and Hormones: What do Hormones Have to do With Allopathic PsychiatryLouis Cady, M.D.

neW FoR PaRt ii – Before delving into an advanced scientific review of hormone replacement therapy, Friday’s morning session will focus entirely on the role of probiotics, nutritional supplements, and telomeres in preventing and treating the common diseases of aging.

A Gut Check on Patient Care: The Role of Probiotics in Preventive Health. Vaughn Johnson, D.O.

14


rEgIStrAtIon InforMAtIon

tWo CoNveNIeNt WAys to ReGIsteR:

Phone: 1-888-222-2966M-F 8:00 am - 5:00 pm, MST.

online: www.worldlinkmedical.com

hotel Accommodations: Hilton Garden InnSalt Lake City, Downtown250 West 600 SouthSalt Lake City, UT 84101Please call 1-801-364-5200, ext. 504. Please ask for Marilyn and reference WorldLink Medical.

Please make reservations early to assure room availability at the corporate rate.

Bring an extra staff member for only $450.00 per person. (Limit two staff members for special pricing. May include administrative support personnel, office managers, medical assistants, RNs, etc.) PLEASE NOTE: Physicians and other prescribing medical pro-fessionals from the same facility each pay full price. They are not considered support staff.

Due to the fast-paced nature of the course, participants MUST HAVE COMPLETED PART I TO ATTEND PART II so the participants can receive the full benefit of course material in Part II. LIKEWISE, PARTICIPANTS MUST HAVE COMPLETED PARTS I AND II TO ATTEND PART III. NO EXCEPTIONS.

RegistRation inCLudes:• First class meeting and conference amenities• Admission to all lectures/discussions• All symposium materials (syllabus containing articles discussed at seminar)

CanCeLLation PoLiCY:There are no refunds on cancellations. However, you may reschedule up to one year following the original course date.

2012 CouRse DAtes - sALt LAke CIty, ut

PaRt i PaRt ii PaRt iii

$795 $795 $795

Jan. 27-29 May 11-13 Oct. 19-21

June 1-3 Sept. 7-9

Aug. 17-19

15

669 West 900 NorthNorth Salt Lake, Utah 84054

PARt I

Jan. 27-29 Salt Lake City, UT June 1-3 Salt Lake City, UT Aug. 17-19 Salt Lake City, UT

PARt II Must have completed Part I to attend Part II

May 11-13 Salt Lake City, UT Sept. 7-9 Salt Lake City, UT

PARt III Must have completed Part II to attend Part III

Oct. 20-21 Salt Lake City, UT

PH: 1-888-222-2966FX: 1-801-294-1401

p: 888-222-2966 · women. he is the director of the preventive medicine clinics of the desert,...

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