osteoarthritis
DESCRIPTION
Osteoarthritis pptTRANSCRIPT
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Textbook readingOSTEOARTHRITIS
Siti Nur AmiraNursyimaaNor Ezyan SyaminSarinah ArsyadVista Ririn SitoAstrid MariaKintan Ramadhani
PEMBIMBING:dr. Proridr.Wiradr.Edwin
Supervisor : dr. Henry Yurianto, M.Phil, Ph.D, SpOT
DIBAWAKAN DALAM RANGKA TUGAS KEPANITERAAN KLINIKBAGIAN ORTOPEDI DAN TRAUMATOLOGIFAKULTAS KEDOKTERAN UNIVERSITAS HASANUDDINMAKASSAR 2015
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Articular cartilagetransmit load and movementfrictional resistance to movement and surface glidinggel-like matrix consisting of a proteoglycan, chondrocytes, type II collagen absorb changes in load and mitigate deformationcollagen network copes with tensile forces
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CapsuleThe soft tissues enclosing the joint surfaceLigamentProvide stability
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SynoviumProvides a nonadherent covering for the articular surfaces and it produces synovial fluidSynovial fluidReducing friction during movement and has slight adhesive properties which assist in maintaining joint stability
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Release of proteolytic enzymesCartilage deformationProteoglycan matrix depletionChondrocyte damageCollagen failure
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Cardinal features
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More joints are affected in women than in men.
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Kellgren JH, Lawrence JS. Radiological assessment of osteoarthritis.Annals of the Rheumatic Diseases 1957;16:494-501
Grade ONo radiological changeGrade 1Doubtful: Minute osteophyte, doubtful significanceGrade 2Minimal: Definite osteophyte, unimpaired joint spaceGrade 3Moderate: Moderate diminution of joint spaceGrade 4Severe: Joint space greatly impaired, with sclerosis of subchondral bone
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*******************The pathologic features readily correlate with the radiographic features of knee OA, i.e. loss of joint space, subchondral cysts, and attempts at repair or regeneration such as sclerosis and osteophytes.