origami protein handout (pdf)

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© Arizona Science Center & Ask A Biologist Funded by the National Center for Research Resources of the National Institutes for Health Page 2 Previous crease Fold here 2 3 1 4 1. Fold a single piece of paper in half diagonally 2. Fold the paper in half diagonally again 3. Your folded paper should look like this 4. Unfold the paper 5 6 7 8 5. Fold the paper in half 6. Fold the paper in half again 7. Your folded paper should look like this 8. Unfold the top layer of the square halfway Paper Protein Activity Part 1: Amino Acids 1

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Page 1: Origami Protein Handout (PDF)

© Arizona Science Center & Ask A Biologist Funded by the National Center for Research Resources of the National Institutes for Health Page 2

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1. Fold a single piece of paper in half diagonally2. Fold the paper in half diagonally again3. Your folded paper should look like this4. Unfold the paper

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5. Fold the paper in half6. Fold the paper in half again7. Your folded paper should look like this8. Unfold the top layer of the square halfway

Paper Protein Activity Part 1: Amino Acids

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Page 2: Origami Protein Handout (PDF)

© Arizona Science Center & Ask A Biologist Funded by the National Center for Research Resources of the National Institutes for Health Page 2

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9. Open the top layer of the square and flatten it into a triangle, using the existing creases10. Your folded paper should look like this11. Flip it over12. Unfold the top layer halfway

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13. Open the top layer and flatten it into a triangle, using the existing creases14. Your folded paper should look like this15. Fold the edges of the top layer only into the center line16. Your folded paper should look like this

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17. Flip it over18. Fold the edges of the top layer only into the center line19. You’ve now completed one amino acid. Repeat these steps with another piece of paper until

you’ve created a total of eight amino acids.

And, that’s it! Once you have amino acids, you are ready to move onto Part 2 to make the protein channel.

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Page 3: Origami Protein Handout (PDF)

© Arizona Science Center & Ask A Biologist Funded by the National Center for Research Resources of the National Institutes for Health Page 2

Paper Protein Activity Part 2: Protein Channel

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1. Make eight amino acids. Each amino acidhas four tabs that open up into a pocket

2. Place two amino acids so the open endsface each other. Insert the top tabs of one amino acid into the tabs of the other

3. Your paper should look like this4. Fold your paper shape in half5. Your amino acid should look like this

5. Your amino acid should look like this

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Page 4: Origami Protein Handout (PDF)

© Arizona Science Center & Ask A Biologist Funded by the National Center for Research Resources of the National Institutes for Health Page 2

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11 12 13 14

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98

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2 31

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6. Continue adding units using step 2-4

7. When you are finished, you should have a string

8. Your protein channel is complete, andshould look like this

9. Your protein model can change shapes byflipping the point to the center, all at once

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