organ & tissue transplants. what is transplantation? replacing a damaged, non- functional or...
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Organ & Tissue Transplants
What is transplantation?
• Replacing a damaged, non-functional or missing organ or tissue with an organ or tissue from another donor
There are multiple types of transplants:Autografts – From the same persons bodyAllografts – From another sourceIsograft – From an identical source (twin or clone)Xenografts – From another species
What can be transplanted?
Organs1
2
3
What can be transplanted?
Tissues1
2
Autografts• Transplant of organ tissue from within the
same person
• Less risk of rejection
• Examples?
Skin Grafts
Bypass Surgery
Tommy John Surgery
Veins used to bypass coronary blockage
Ulnar collateral ligament replaced with one from elsewhere in body
Allografts• Transplant of organ tissue from one person to
another
• Most transplants are allografts
• Donors can be living or deceasedTissues can be stored for transplants up to 5 years Organs last about 24 hours after death
• Examples?
Face Transplant
Kidney Transplant
First successful full facial transplant was in Barcelona in 2010
Xenografts• Transplant of organ tissue from another species
• High risk of rejection
• Lifespan and disease issues
• But long waitlists for organs make this potentially useful in the future
Baby Fae
• Received a baboon heart transplant in 1984
• Incompatible blood types (O vs AB)
• Experimental and contraversial!
Isografts• Transplant of organ tissue from identical source
• Very rare because of requirements, but very successful! Low rejection rate.