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H11-01076-04 C-OGM 02/12 ©2012 OptumRx, Inc.

Oral Glucose Medications Diabetes ActiveCare

When doctors prescribe oral medications to treat type 2 diabetes, many options are available. This guide may help your patients identify the name of the oral medication that has been prescribed for them — and help avoid confusion.

C M Y K

PROJECT # H11-01076-04 C-OGM START DATE: 1/23/12

APP’D: 2/16/12

PRINT SIZE 11" x 17"BLEED N/AMEDIA Printed poster

COLOR CMYK for COATED STOCK

COMPONENT: Cholesterol- Oral Glucose Meds Chart

Name That Medicine

Alpha-Glucosidase InhibitorsDrug Name Representative

Brand NameDoses Available (mg)

How it Works

Acarbose Precose® 2550100

Inhibitscarbohydratedigestion todelay and lessen the rise in post meal glucose levels

Miglitol Glyset® 2550100

Dopamine AgonistDrug Name Representative

Brand NameDoses Available (mg)

How it Works

Bromocriptine Mesylate

Cycloset® 0.8

Unclear

DPP-4 InhibitorsDrug Name Representative

Brand NameDoses Available (mg)

How it Works

Linagliptin Tradjenta™ 5 Enhances function of both alpha and beta cells to improve glucose uptake and decrease glucoseproduction

Sitagliptin Phosphate

Januvia® 2550100

SaxagliptinPhosphate

Onglyza® 2.55

ThiazolidinedionesDrug Name Representative

Brand NameDoses Available (mg)

How it Works

Pioglitizone Actos® 153045

Increases insulinsensitivity toincrease glucoseuptake andreduce bloodglucose levels

MeglitinidesDrug Name* Indicates Generic

is Available

Representative Brand Name

Doses Available (mg)

How it Works

Nateglinide* Starlix® 60120

Short acting agents that increase insulin secretion and decrease bloodglucose in people with capacity toproduce insulin

Repaglinide Prandin® 0.51.02.0

SulfonylureasDrug Name* Indicates Generic

is Available

Representative Brand Name

Doses Available (mg)

How it Works

Chlorpropamide* Diabenese 250 Short acting agents that increase insulin secretion and decrease bloodglucose in people with capacity toproduce insulin

Glimepiride* Amaryl® 124

Glipizide* Glucotrol® 510

GlipizideExtendedRelease*

Glucotrol® XL 2.55.010.0

Glyburide* Diabeta® 1.25 2.50 5.00

GlyburideMicronized*

Glynase®

Pres Tab®1.53.06.0

Tolazamide* Tolinase 250500

Tolbutamide* Orinase 500

BiguanidesDrug Name* Indicates Generic

is Available

Representative Brand Name

Doses Available (mg)

How it Works

Metformin* Glucophage® 500850 1000

Increases insulinsensitivity todecrease bloodglucose levels:• Decreases

liver glucose production

• Increases insulin sensitivity

Metformin Extended Release*

Glucophage® XR

500750

Metformin Liquid

Riomet® 500/5ml

CombinationsDrug Name* Indicates Generic

is Available

Representative Brand Name

Doses Available (mg)

How it Works

Actos/Metformin

ACTOplus met™ 15/500 15/850

Enhancesglucose uptakeand decreasesglucose production

Linagliptin/ Metformin

Jentadueto™ 2.5/500 2.5/850 2.5/1000

Sitagliptin/Metformin

JANUMET® 50/50050/1000

Glipizide/Metformin*

Metaglip™ 2.5/250 2.5/500 5/500

Increases insulinproductionand decreases glucose productionGlyburide/

Metformin*Glucovance® 1.25/250

2.5/500 5/500

Bile Acid SequestrantDrug Name* Indicates Generic

is Available

Representative Brand Name

Doses Available

How it Works

Colesevelam* Welchol® 3.75 gm Unclear

In addition to medications included here, multiple combination medications continue to become available, combining the mechanisms of action of two classes of drugs in one medication. Examples of such include DuetactTM and JANUMET®.

Sources: Adapted from www.drugdigest.org, and The Art and Science of Diabetes Self-Management Education, 2010.

Invite your Medicare patients to order their diabetes testing supplies today! 1-800-364-7176 | www.optumrx.com/diabetes

Also available in 625 mg tablets