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Optical recognition of polyps

Bassioukas P. Stefanos

Department of Advanced Therapeutic Endoscopy, Bioclinic Hospital Athens

Is optical diagnosis and interpretation of colonic polyps useful?

Clinical case 1:

• 56 year-old male diagnosed with a recto-sigmoid LST-G mixed type under whitelight endoscopy, approximately 7cm

• Biopsies (10 samples) showed adenoma with low to intermediate dysplasia

• Due to tumor size CT scan and Pelvic MRI was performed

• MRI diagnosed wall thickening (possible T2 stage tumor), with a 10cm length occupying more than 50% of lumen periphery

Treatment Decision

• Surgery – low anterior resection

• But …… biopsies are negative for infiltrative malignancy….

• New image enhanced endoscopy and targeted biopsies for diagnosis

14x12 cm, Fibrosis Grade 3 Adenoma with low grade dysplasia and focal high grade

dysplasia, R0 resection

Clinical case 2

• 74 year-old female diagnosed with a 3 cm ascending colon LST-NG type polyp

• Biopsies showed high grade dysplasia

Treatment Decision

• It is not a cancer…

• Let’s try en-block removal for definite diagnosis

AdenoCa

Lesion morphologyParis Classification

Risk Stratification for Covert Invasive Cancer Among Patients Referred for Colonic Endoscopic Mucosal Resection:

A Large Multicenter Cohort Burgess N et al. Gastroenterology 2017;153:732–742

Am J Gastroenterol. 2017 Jan;112(1):54-64.

Magnification Chromoendoscopy

Kudo Pit-Pattern

Deep sm 28%

Deep sm

90%

Image Enhanced Endoscopy

overall accuracy for sm 70%

Surface/Vessel architectureMagnification virtual endoscopy

Sm1, V/Ly (0)

Conclusions

• Optical recognition is very important to determine diagnosis and choose the right therapy

• Use high definition endoscopes with image enhanced technology in cases of IIc-depressed lesions and LST-NG/G mixed types

• If this is not possible, just spray 0.3% Indigo Carmine for better interpretation

• Do not take multiple biopsies if you consider resectability. Fibrosis!! Do not tattoo under the lesion!

• One or two targeted samples are sufficient.

• Share your cases with other colleagues. We all get better endoscopists…

Optical recognition of polyps

Bassioukas P. Stefanos

Department of Advanced Therapeutic Endoscopy, Bioclinic Hospital Athens