opportunities in biotechnology. biotechnology facts more than 250 million people have received...

Opportunities

in

BIOTECHNOLOGY

Biotechnology Facts

• More than 250 million people have received biotech drug products and vaccines

• 350 biotech drug products and vaccines currently in clinical trials

• Hundreds of medical diagnostic tests approved

• Biotech crop acreage estimated at 125 million acres

Biotechnology Facts

• 1273 biotechnology companies in the U.S., of which over 300 are publicly held

• U.S. biotechnology industry employs 150,000 people

• $10.7 billion spent on R&D in 2000

• Revenues of $22.3 billion

0

5

10

15

20

25

30

1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000

$

Source: Ernst & Young

Exhibit 9: Biotech Revenues Increase(public and private)

Ind

us

try

Re

ve

nu

es

($

in

Bil

lio

ns

)

Year

Diagnostics/Radiopharmaceuticals/Contrast Agents 4%

Ophthalmic/Ophthalmologic/Eye 4%

Vaccines/Adjuvants 4%

Gynecological & Genito-Urinary 3%

Other 15%

Cancer 28%

Sources: NDA Pipeline, Ernst & Young

Exhibit 11: The Biotech Pipeline: Phase III Trials

Respiratory/Pulmonary 5%

Metabolic 5%

Blood & Coagulation 6%

Cardiovascular 6%

Infectious & Viral Diseases 9%

Nervous System 11%


Years

0 16842 6 10 12 14

Post-Marketing Testing

FDA Review & Approval

Phase III (1,000-5,000 patients volunteers used to monitor reactions to long-term drug use)

Phase II (100-300 healthy volunteers used to check for efficacy and side effects)

Phase I (20-30 healthy volunteers used to check for safety and dosage)

Preclinical Testing(Lab and animal testing)

Discovery(2-10 years)

Overview of the Drug Discovery Process


5,000 to 10,000 compounds screened

250 lead candidates in preclinical testing

5 drug candidates enter clinical testing: 80% pass Phase 1

30% pass Phase 2

80% pass Phase 3

One drug approved by the FDA

Overview of the Drug Screening and Selection Process

Clinical Development– Phased Clinical Development

• Phase 1: define dosing regimen(s) & acute safety• Phase 2: estimate efficacy & safety in patients• Phase 3: prove comparative efficacy & safety• Phase 3b & 4: differentiate in the marketplace

– “Plan for Success” of every compound• parallel uncoordinated activities• high resource expenditures

What Does Industry Look For?• Ethical

• Energetic

• Creative

• Good training in fundamentals of scientific inquiry

• Relevant background in specific discipline or field

• Good "people skills"– communication– team orientation

• Scientific Method/Experimental Design A

• Technical Competence A

• Communication:

Scientific hypotheses/data/results A-C

As member of interdisciplinary team C-

Project/team leadership & mgmt. D

Academic Training:An Industrial Report Card

What Kinds of Teams Do You Find in a Biotech Company?

• Project Teams (Research)• Product Development Teams• Money Raising Teams• Business Development Teams• Marketing and Sales Teams

Characteristics of Great Teams

• Great teams have to work together

• Members have a common vision


• People on great teams are optimistic, not realistic. They believe they can do things no one else has ever done before. This is not realism.

• Studies have shown that optimists - even when their optimism isn’t warranted - accomplish more than people who are pessimists.


• On great teams, the right person has the right job. It’s absolutely essential to find the right niche for each person or to let them find their own perfect niche.

• It’s too easy to believe that people are interchangeable. Truly talented people are rarely interchangeable.

• Great teams are not micro-managed.

• Members of the group need to have relative autonomy in order to be creative.



• Share information effectively.

• Require a lot of ideas and these ideas have to be shared.

• Prefer civility as the social climate for creative collaboration

TOYS $$$ Education

• Write down ONE thing from each slide.

• Title your paper “Toys $$$ Education”

• Place your name, pd, date, etc on paper

• Your binder should now have:– 1. Scavenger hunt– 2. Latin words– 3. This paper

No High School

• Own boss Millions to bankruptcy

• $40,000 - $80,000 - $1,000,000+

• ??????????

• Fast food $5,000 - $15,000• Work for Family ?

• Do they want you to work for them ???

High School degree

• Non specialized + doing what others tell you to do everyday $20,000 - $40,000

• ???

What about that job at the mills my parents got right out of high school?

• The mills are highering fewer people. All new highers have education beyond high school.

Trade / AA degree

• Factory laborer $20,000 - $65,000

• Mechanic, Electrician, Plumber

• Nurse, Message therapist, Secretary

• $20,000 - $80,000

• Store Manager $30,000 - $80,000

• ???

College

• Specialized in a field

• Education $35,000 - $65,000

• Environmental $25,000 - $95,000

• Business $30,000 - $100,000

• ???

Masters / PhD

• Doctor $100,000 - $300,000

• Lawyer $60,000 - $400,000

• Director of business$80,000 - $160,000

• VP of a business $120,000 - $500,000

• CEO / Boss $280,000 - $800,000+

What do you want?

• Want Need for Income• Apartment $25,000

– (what education do you need to afford an apartment?)– (If you have a roommate and share $, what education do you need?)

• House small 3 bedroom $40,000» ($200,000)

• House medium 3 bdrm $60,000» ($250,000)

• House w/land, 10 acres ($300,000 +) $70,000• Large house $100,000+

» ($350,000+)

Toys

• Want Extra Income needed• Nice car $5,000 / year more

» New car ($20,000)

• Boat $5,000• Wave runner, motor bike, 4 wheeler $3,000 /yr/each

» ($3,000 each + supplies)

• Vacations $2,000/person in family» ($1,500 min to Hawaii, Vegas, Disneyland)

• Get Married $5,000-20,000 more• New clothes, eat out, etc $???,???

Retirement??????????

• Do you plan on working your entire life?

• Are you saving money so you can retire when you are 65 years old? Add $5,000+/yr

• What if your car breaks down? $1,000

• What if you get sick? $1,000-$10,000

Education level

• 1. Add up what you want in the future in regards to the income you’ll need to have.

• 2. What education level will you need and how many years till you’ll probably get there?

• Answer ____________________

opportunities in biotechnology. biotechnology facts more than 250 million people have received...

Documents