occupational and environmental medicine · 44 cocarla a, corneag, dengel h,gabors, milea m,papilian...

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British Journal of Industrial Medicine 1993;50: 1057 From January 1994 the British Journal of Industrial Medicine will be redesigned to appear in A4 size with a new title: Occupational and Environmental Medicine The new editor will be Dr Anne Cockcroft, consultant and senior lecturer in occupational medicine, Royal Free Hospital and School of Medicine. She will continue the sound tradition developed by Dr Tony Waldron of publishing good scientific papers on industrial medicine, and in the January issue will give her views on the directions in which the jotrrnal might evolve in the field of occupational and environmental medicine. New papers and correspondence about papers previously submitted should be sent to: Dr Anne Cockcroft Occupational and Environmental Medicine BMA House Tavistock Square London WC 1 H 9JR United Kingdom 1057

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Page 1: Occupational and Environmental Medicine · 44 Cocarla A, CorneaG, Dengel H,GaborS, Milea M,Papilian VV. Carbon black pneumoconiosis. IntArch OccupEnviron Health 1976;36:217-28. (In

British Journal of Industrial Medicine 1993;50: 1057

From January 1994 the British Journal of Industrial Medicine will be redesigned to appear in A4size with a new title:

Occupational and Environmental Medicine

The new editor will be Dr Anne Cockcroft, consultant and senior lecturer in occupationalmedicine, Royal Free Hospital and School of Medicine. She will continue the sound traditiondeveloped by Dr Tony Waldron of publishing good scientific papers on industrial medicine,and in the January issue will give her views on the directions in which the jotrrnal might evolvein the field of occupational and environmental medicine.

New papers and correspondenceabout papers previously submittedshould be sent to:

Dr Anne CockcroftOccupational and Environmental MedicineBMA HouseTavistock SquareLondon WC 1H 9JRUnited Kingdom

1057

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British Journal of Industnial Medicine 1993;50:1058-1072

Editor's Choice

Dust exposure and mortality in chrysotile mining,1910-75by J C McDonald, F D K Liddell, GW Gibbs, G E Eyssen, and A D McDonald

(British Journal of Industrial Medicine 1980;37: 11-24)

Corbett McDonald has had a distinguished andvaried career at the Public Health LaboratoryService, at McGill University and at the LondonSchool of Hygiene and Tropical Medicine, andnow-in so called retirement-at the NationalHeart and Lung Institute. His outstanding contri-bution to the field of occupational epidemiologyhas been in the field of asbestos related diseases.The present paper describes almost the end resultof a study begun in 1966 and carried on for 12years on a cohort of 11 379 workers exposed tochrysotile in the asbestos mines and mills ofQuebec. This work elegantly demonstrates that"Essentially linear relationships [exist] betweenindices of exposure, based on dust concentration(mpcf) multiplied by length of service, and lung.cancer, pneumoconiosis, and total number ofdeaths". Furthermore, McDonald and his col-

leagues go on to say that they "are now able toassess, with reasonable confidence, the mortalityrisk associated with work at different levels of dustconcentrations". They also claimed that it would bepossible, "for social decisions to be made as to whatlevel, if any, is 'acceptable'."

McDonald's work over the years showed con-

clusively that the development of asbestos relateddiseases was a function of the degree and durationof exposure and laid low the fallacy of the notionthat a single fibre could cause cancer. One mighthave expected his observations would have beenwelcomed, implying as they did that there wereconditions under which asbestos could be workedwithout harm to health. But this was not to be so.He and his colleagues were subjected to a campaignof vituperation that was designed to achievepolitical rather than scientific ends. So far as I knowhe has never fully given an account of this episodeand he may find it too painful to do so, although itwould certainly be enlightening and instructive.

As part of the 50th birthday celebration, we are arranging to reprint 12 papers, the Editor'sChoice, which have appeared in previous issues of the Journal. They have been chosenpartly to illustrate the range and scope of the Journal over the years and partly becausethey are or were important in their day. More significantly, they have been chosen becausethey exemplify some of the best in scientific writing and can all be read with great pleasureand all who wish to communicate their observations, their ideas, or their enthusiasmswould do well to study them and learn from them.We will publish one paper each month through the year and they will appear in the

order in which they were originally published.

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McDonald, Liddell, Gibbs, Eyssen, and McDonald

19 Elwood PC, Cochrane AL. A follow-up study of workersfrom an asbestos factory. Br J Ind Med 1964;21:304-7.

'" Weiss W. Mortality of a cohort exposed to chrysotileasbestos. JOM 1977;19:737-40.

21 Selikoff IJ, Hammond EC. Multiple risk factors inenvironmental cancer. In: Proceedings of Con.ference onPersons at High Risk of Cancer: an Approach to CancerEtiology and Control, December 10-12 1974. Key.Biscayne, Florida, 1975.

" McDonald AD, McDonald JC. Mesothelioma aftercrocidolite exposure during gas mask manufacture.

Environ Res 1978;17:340-6."3 McDonald JC, McDonald AD. Epidemiology of

mesothelioma from estimated incidence. Prey Med1977 ;6:426-46.

"4 McDonald JC. Exposure relationships and malignantmesothelioma. In: Glen HW, ed. Proceedings ofAsbestos Symposium, Johannesburg 3-7 October 1977.Randburg: National Institute for Metallurgy, 1978.

"Doll R. Retrospective and prospective studies. In: WittsLJ, ed. Medical surveys and clinical trials. London:Oxford University Press, 1964:84-5.

Vancouver style

All manuscripts submitted to Occup Environ Medshould conform to the uniform requirements formanuscripts submitted to biomedical journals(known as the Vancouver style.)

Occup Environ Med, together with many otherinternational biomedical journals, has agreed toaccept articles prepared in accordance with theVancouver style. The style (described in full inthe BM7, 24 February 1979, p 532) is intendedto standardise requirements for authors.

References should be numbered consecutivelyin the order in which they are first mentioned inthe text by Arabic numerals above the line on eachoccasion the reference is cited (Manson' confirmedother reports2-5 . . .). In future references to paperssubmitted to Occup Environ Med should include:the names of all authors if there are seven or less

or, if there are more, the first six followed by et al;the title of journal articles or book chapters; thetitles of journals abbreviated according to thestyle of Index Medicus; and the first and final pagenumbers of the article or chapter. Titles not inIndex Medicus should be given in full.

Examples of common forms of references are:

1 International Steering Committee of Medical Editors,Uniform requirements for manuscripts submitted to bio-medical journals. BrMedJ7 1979;1:532-5.

2 Soter NA, Wasserman SI, Austen KF. Cold urticaria: releaseinto the circulation of histamine and eosinophil chemotac-tic factor of anaphylaxis during cold challenge. N Engl J7Med 1976;294:687-90.

3 Weinstein L, Swartz MN. Pathogenic properties of invadingmicro-organisms. In: Sodeman WA Jr, Sodeman WA,eds. Pathologic physiology, mechanisms of disease. Phila-delphia: W B Saunders, 1974:457-72.

24

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The 1891-1920 birth cohort of Quebec chrystolite miners and millers: mortality 1976-88

4 Liddell FDK, McDonald JC, Thomas DC. Methods of cohortanalysis: appraisal by application to asbestos mining. Journalof the Royal Statistical Society Series A 1977;140:469-9 1.

5 McDonald JC, Liddell FDK, Gibbs GW, Eyssen GE,McDonald AD. Dust exposure and mortality in chrysotilemining, 1910-75. BrJ7 Ind Med 1980;37:11-24.

6 Liddell FDK. Maintaining progress in the analysis of cohortstudies. In: Hogstedt C, Reuterwall C, eds. Progress in occu-pational epidemiology. Amsterdam: Elsevier, 1988:71-4.

7 Peto J, Seidman H, Selikoff IJ. Mesothelioma mortality inasbestos workers: implications for models of carcinogenesisand risk assessment. BrJ3 Cancer 1982;45:124-35.

8 Gibbs GW, Lachance M. Dust exposure in the chrysotileasbestos mines and mills of Quebec. Arch Environ Health1972;24: 189-97.

9 Berry G. The analysis of mortality by the subject-yearsmethod. Biometrics 1983;39:173-84.

10 Coleman MP, Hermon C, Douglas A. Person-years (PYRS): aFortran program for cohort study analysis. Lyon: InternationalAgency for Research on Cancer, 1989. (Internal Report No89/006.)

11 Goldberg M. Calculation of population mortality rates for theProvince of Quebec, Rural Quebec and the Eastern Townships.Privately circulated, 1989.

12 Berry G, Newhouse ML, Antonis P. Combined effects ofasbestos and smoking on mortality from lung cancer andmesothelioma in factory workers. Br 7 Ind Med 1985;42:12-8.

13 Enterline PE, Hartley J, Henderson V. Asbestos and cancer: acohort followed up to death. Br 7 Ind Med 1987;44:396-401.

14 McDonald AD, Liddell FDK, McDonald JC. Malignantmesothelioma in Quebec chrystolite miners and millers: apreliminary report. In: Proceedings of the 9th InternationalSymposium on Epidemiology in Occupational Health,Cincinnati, Ohio, September 1992. (In press.)

15 Selikoff IJ, Hammond EC, Seidman H. Mortality experienceof insulation workers in the United States and Canada,1943-1976. Ann NYAcad Sci 1979;330:91-116.

16 Sluis-Cremer GK, Liddell FDK, Logan WPD, BezuidenhoutBN. The mortality of amphibole miners in South Africa,1946-80. Br7 Ind Med 1992;49:566-75.

17 Vacek PM, McDonald JC. Risk assessment using exposureintensity: an application to vermiculite mining. Br3 Ind Med1991 ;48:543-7.

Accepted 5 April 1993

Correspondence and editorials

Occupational and Environmental Medicine wel- to an absolute minimum. Letters are accepted oncomes correspondence relating to any of the the understanding that they may be subject tomaterial appearing in the journal. Results from editorial revision and shortening.preliminary or small scale studies may also be The journal also publishes editorials which arepublished in the correspondence column if this normally specially commissioned. The Editorseems appropriate. Letters should be not more welcomes suggestions regarding suitable topics;than 500 words in length and contain a minimum those wishing to submit an editorial, however,of references. Tables and figures should be kept should do so only after discussion with the Editor.

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Gardiner, Trethowan, Harrington, Rossiter, Calvert

39 Komarova LT. Hygienic evaluation of the production of car-bon black by the furnace method. Gig Tr Prof Zabol1973;17:32-6. (In Russian.)

40 Slepicka J, Eisler L, Mirejovsky P, Simecek R. Lung changesin workers due to long-term employment in the productionof carbon black. 1racovni Lekarstvi 1970;22:276-81. (InCzechoslavakian.)

41 Troitskaya NA, Velichkovskii BT, Bikmullina SK, SazhinaTG, Corodnova NV, Andreyeva TD. Substantiation of themaximum permissible concentration of industrial carbonblack in the air of production areas. Gigiena Truda iProfessional'nye Zabolevaniya 1975;17:32-6. (In Russian.)

42 Valic F, Beritic-Stahuljak D, Mark B. A follow-up study offunctional and radiological lung changes in carbon blackexposure. Internationales Archiv fur Arbeitsmedizin1975;34:51-63. (In German.)

43 Wehr KL, Johanson WG, Chapman JS, Pierce AK.Pneumoconiosis among activated carbon workers. ArchEnviron Health 1975;30:578-82.

44 Cocarla A, Cornea G, Dengel H, Gabor S, Milea M, PapilianVV. Carbon black pneumoconiosis. Int Arch Occup EnvironHealth 1976;36:217-28. (In French.)

45 Kollo RM. A health evaluation of working conditions in a

channel black plant. Trudy Leningradskogo Sanitarno-Gigienicheskogo 1980;62:128. (In Russian.)

46 Beritic-Stahuljak D, Cigula M, Rubala D, Valic F, Mark B.Changes in the respiratory system of carbon black workersover a period of fourteen years. Acta Medica Yugoslavia1980;34:363-72. (In Russian.)

47 Beck B, Gohlke R, Sturm W, Bergmann L, Wolf E. Carbonblack lung as an occupational disease. Z Erkrank Atm-Org1985;164:254-66. (In German.)

48 Sheers G, Rossiter CE, Gilson JC, Mackenzie FAF. UKNaval dockyards asbestosis study: radiological methods inthe surveillance of workers exposed to asbestos. Br J IndMed 1978;35:195-203.

49 Komarova LT. The effect of air contamination in the produc-tion of carbon black on the morbidity and health of theworkers. Nauchnye Trudy, Ormkii Meditsinski Institut1965;61:115-21. (In Russian.)

50 Oleru UG, Elegbeleye 00, Enu CC, Olumide YM.Pulmonary function and symptoms of Nigerian workersexposed to carbon black in dry cell battery and tire factories.Environ Res 1983;30:161-8.

Accepted 22 February 1993

Destruction ofmanuscripts

From 1 July 1985 articles submitted for publicationwill not be returned. Authors whose papers arerejected will be advised of the decision and themanuscripts will be kept under security for threemonths to deal with any inquiries and thendestroyed.

1096

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Bnitish Journal ofIndustrial Medicine 1993;50:1128-1134

AUTHOR INDEX TO VOLUME 50, 1993

A

ABRAHAM J see FoRST L S and ABRAHAM JADAMSSON M see PERSSON P et alALEGIANI S S see BISANTI L et alAu.EN J A see McKENNA K M et alAMELTL J see CHOUDAT D et alAMERASINGHE P see SENANAYAKE N et alAMLEE E see FANDREM S I et alANDERSEN A see DANIELSEN T E et al

ELLINGSEN D G et alFANDREM S I et al

ANDERSEN J B see GLtNEL P et alANDERSON K see McCoNNELL R et alANDERSON K E see McCoNNELL R et alANGLE C see NELSON K et alANUNDI H see EDLING C et al

WALLES S A S et alATTFIELD M D see SEIXAS N S et alAYRES J G see GANNON P F G et al

B

BABAPULLE M see SENANAYAKE N et alBANNISTER R M see STRAUSS M E et alBARBON R see CARDENAS A et alBARREGARD L see ELLINGSEN D G et al

SALLSTEN G et alBARRICK E D see STRAUSS M E et alBARUFFN A see PISATI G et alBASA-CIERPIALEK Z see BECHER H et alBASANAYAKE V see SENANAYAKE N et alBAUM JM see LEINSTER P et alBAXTER P J see LEINSTER P et alBECHER H et al: Effect of occupational air pollutants on

various histological types of lung cancer: a population basedcase-control study, 136

BEGIN R et al: Computed tomography in the early detection ofasbestosis, 689see also DANIEL H et al

BEKESI J G see FISCHBEIN A et alBELIN L see NnLsSON R et alBENAMGHAR L see CHAU N et alBENDER J R: Pulmonary effects of exposure to fine fibreglass:

irregular opacities and small airways obstruction:correspondence, 381

BENSON L 0, TETA M J: Mortality due to pancreatic and lym-phopoietic cancers in chlorohydrin production workers, 710see also TETA M J et al

BERITIC T: Misconceptions about blood lead concentrations:forum, 1123

BERNARD A see HOTZ P et alBERNARD A M see CARDENAS A et al

ROELS H et alBERTAUX L see DESCHAMPS D et alBERTRAND J P see CHAU N et alBERTRAND P see BEGIN R et alBEULINK G D J see VAN SrrrERT N J et al

BIREMBAUT Y see MOUUN J J et alBISANTI L et al: Cancer mortality in ethylene oxide workers,317

BLANc M see MOuLIN J J et alBLANN A D see MCKENNA KM et alBLASCHKE E see TORNLING G et alBLOTW J see LINETM S et alBODETIER-BADE MM see VAN RooIJ J G M et alBOMAN A see CAMNER P et alBOND G G, ROSSBACHER R: A review of potential human

carcinogenicity of the chlorophenoxy herbicides MCPA,MCPP, and 2,4-DP, 340

BOOGAARD P J et al: Effects of exposure to low concentrationsof chlorinated hydrocarbons on the kidney and liver ofindustrial workers, 331see also VAN SrrrERT N J et al

BORM P J A, SCHINS P F R: Lymphocyte subsets in subjectsexposed to asbestos: changes in circulating natural killercells: correspondence, 575see also EvELo C T A et al

Bos R P see EVELO C T A et alBoTTA M see MAGNANI C et alBOULENGUEZ C see MAREZ T et alBRESLOW N E see CHECKOWAY H et alBROCHARD P see CHOUDAT D et alBRUCH J et al: Toxicological investigations on silicon carbide.

1. Inhalation studies, 797; 2. In vitro cell tests and longterm injection tests, 807

BUCHET J P see CARDENAS A et alROELS H et alSWENNEN B et al

BUCKELL M et al. Chronic mercury poisoning (1946,3,55):editor's choice, 97

BUDEL P see MAGNANI C et alBUNDSCHUH I see ROELS H et alBURGE P S see GANNON P F G et al

C

CAFFARI B see BISANTI L et alCALVERT I A see GARDINER K et alCAMNER P et al: Inhalation of cobalt by sensitised guinea pigs:

effects on the lungs, 753CAPKUN V see ETEROVIC D et alCARDENAS A et al: Markers of early renal changes induced by

industrial pollutants. I Application to workers exposed to

mercury vapour, 17: II Application to workers exposed tolead, 28see also ROELS H et al

CARPENTER R G et al: Death rates of miners and ex-minerswith and without coalworkers' pneumoconiosis in SouthWales (1956,13,102): editor's choice, 577

CASE R A M et al: Tumours of the urinary bladder in work-men engaged in the manufacture and use of certain dyestuffintermediates in the British chemical industry (1954,11,75):editor's choice, 389

CASSOU B see DERRIENNIC F et alCHAN J see MUIR D C F et al

1128

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Author Index

CHAU N et al: Mortality of iron miners in Lorraine (France):relations between lung function and respiratory symptomsand subsequent mortality, 1017Mortality in retired coke oven plant workers, 127

CHECKOWAY H et al: Mortality among workers in thediatomaceous earth industry, 586

CHEN R et al: Mortality from lung cancer among copperminers, 505

CHETTLE D R see GORDON C L et alCHIA K S see LEE J and CHIA K SCHIAZZE L et al: A case-control study of malignant and non-

malignant disease among employees of a fibreglass manu-facturing facility: correspondence, 287A case-control study of malignant and non-malignantrespiratory disease among employees of a fibreglass manu-facturing facility. II Exposure assessment, 717

CHINN D J et al: Pre-employment lung function at age 16years as a guide to lung function in adult life, 422

CHMIELNICKA J see MATCZAKW and CHMIELNICKA JCHOUDAT D et al: Respiratory symptoms, lung function, andpneumoconiosis among self employed dental technicians, 443

CHURG A, STEVENS B: Absence of amosite asbestos in airwaymucosa of non-smoking long term workers with occupa-tional exposure to asbestos, 355

CLAPP R see McCoNNEiLL R et alCLARKEW G see CARPENTER R G et alCLAUSEN J et al. Lung function in insulation workers, 252COCHRANE A L see CARPENTER R G et alCoLE R B see GANNON P F G et alCOLMAN N see BEGIN R et alCOLMSJO A see LOF A et alCOMMINS B T see WALLER R E et alCONNELLAN S see GANNON P F G et alCOOKSONW 0 C M see DE KLERK N H et alCoRN C J see DODSON R F et alCOTES J E see CHINN D J et alCOULTAS D B see MuLLoY K B et alCRUDDAS A M see GARDNER M J et alCRUICKSHANK C N D, SQUIRE J R: Skin cancer in the

engineering industry from the use of mineral oil (1950,7,1):editor's choice, 289

D

DALENE M see PERSSON P et alDALLY S see DESCHAMPS D et alDALPHIN J C et al: Prevalence and risk factors for chronic

bronchitis and farmer's lung in French dairy farmers, 941DANIEL H et al: Effects of phosphorylation of chrysotile on

pleuropulmonary fibrogenicity and carcinogenicity, 167DANIELL W et al: Neuropsychological performance and sol-

vent exposure among car body repair shop workers, 368:correspondence reply, 1 126

DANIELSEN T E et at: Incidence of cancer among welders ofmild steel and other shipyard workers, 1097

DANILOVSKAJA Y V see GUSEV V A et alDAVIS J M G: The need for standardised testing procedures

for all products capable of liberating respirable fibres: theexample of materials based on cellulose: forum, 187

DE BEER M see MURRAY J et alDE BROE M E see CARDENAS A et al

ROELS H et alDE GAUDEMARIs R see MOULIN J J et alDE KLERK N H et al: Radiographic abnormalities and mortal-

ity in subjects with exposure to crocidolite, 902DEBIEuvRE D see DALPHIN J C et alDEBIOLLES M P see MOULIN J J et alDEMERS P A see CHECKOWAY H et al

DEPIERRE A see DALPHIN J C et alDERRIENNIC F et al: Evolution of osteoarticular disorders as a

function of past heavy physical work factors: longitudinalanalysis of 627 retired subjects living in the Paris area, 851

DESCHAMPS D et al: Evoked potentials and cerebral bloodflow in solvent induced psycho-organic syndrome, 325

DIAMOND R see WHITE R F et alDODSON R F et al: Analysis of ferruginous bodies in bron-

choalveolar lavage from foundry workers, 1032DoLL R: Mortality from lung cancer in asbestos workers

(1955,12,81): editor's choice, 484DONALDSON K see LI X Y et alDUBIEz A see DALPHIN J C et alDUFRESNE A see McDONALD J C et alDujiy Z see ETEROVId D et alDUNNIGAN J: Chrysotile asbestos revisited: correspondence, 862DYER J et al: Plumboporphyria (ALAD deficiency) in a lead

worker: a scenario for potential diagnostic confusion, 1 1 19

E

EDLING C et al: Increase in neuropsychiatric symptoms afteroccupational exposure to low levels of styrene, 843Occupational exposure to organic solvents as a cause ofsleep apnoea, 276see also FRIIS L et al; WALLES S A S et al

EDME J L see MAREZ T et alEDWARDS J W, PRIESTLY B G: Sister chromatid exchanges in

lymphocytes of petroleum retailers, 149EFSKIND J see ELLINGSEN D G et alEKLUND A see TORNLING G et alELINDER C G see JARUP L and ELINDER C GELLAPOLA S B see SENANAYAKE N et alELLER P M: Neuropsychological performance and solvent

exposure among car body repair shop workers: corres-pondence, 1126

ELLINGSEN D G et al: Assessment of renal dysfunction inworkers previously exposed to mercury vapour at a

chloralkali plant, 881Incidence of cancer and mortality among workers exposed tomercury vapour in the Norwegian chloralkali industry, 875Mercury and selenium in workers previously exposed tomercury vapour at a chloralkali plant, 745Relation between exposure related indices and neurologicaland neurophysiological effects in workers previouslyexposed to mercury vapour, 736

ELLIOTT C see CHINN D J et alERICSSON J L E see LINET M S et alETEROViR D et al: High resolution pulmonary computedtomography scans quantified by analysis of density distribu-tion: application to asbestosis, 514

EVANOFF B A et al: Mortality and incidence of cancer in acohort of Swedish chirnney sweeps: an extended follow upstudy, 450

EVELO C T A et al: Decreased glutathione content andglutathione S-transferase activity in red blood cells of coalminers with early stages of pneumoconiosis, 633

EYSSEN G E see McDONALD J C et al

F

FABBRI LM see VANDENPLAS 0 et alFANDRFM S I et al: Incidence of cancer among workers in aNorwegian nitrate fertiliser plant, 647

FAUCON D see MOULiN J J et alFECHNER M see CHINN D J et alFELS L M see CARDENAS A et alFIGUEREDO A see CHAU N et al

1129

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Author Index

FILION R see BEGIN R et alFIORETTA G see GUBERAN E et alFISCHBEIN A et al: The immune system as target for subclini-

cal lead related toxicity, 185FLAK E see BECHER H et alFLYVHOLM M-A: Contact allergens in registered cleaning

agents for industrial and household use, 1043FORST L S, ABRAHAM J: Hypersensitivity pneumonitis present-

ing as sarcoidosis, 497FOURNIER J see NEjJARI A et alFRANCHINI I see CARDENAS A et al

ROELS H et alFRAuMENI J F see LINET M S et alFRECH W see ELLINGSEN D G et alFRIs L et al: Mortality and incidence of cancer among sewage

workers: a retrospective cohort study, 653FRYAR C see CHIAZZE L et alFUjINo A see MORIMOTO Y et alFUNAKI M see YANo E et al

G

GAARDER P I see ELUNGSEN D G et alGABREELS F see ROELEVELD N et alGANNON P F G et al: Health, employment, and financial out-comes in workers with occupational asthma, 491The SHIELD scheme in the West Midlands Region,United Kingdom, 791

GARCIA J G N see DODSON R F et alGARDINER K et al: Respiratory health effects of carbon black: a

survey of European carbon black workers, 1082GARDNER M J et al: A cohort study of workers exposed toformaldehyde in the British chemical industry: an update,827see also SHORE R E et al

GARNIER R see DESCHAMPS D et alGARRICK D P see DYER J et alGARY Y see MouLiN J J et alGIBBS G W: Biological indicators and their clinical signifi-

cance in persons exposed to mineral fibres: report of aworkshop held in Japan, 24-25 November 1991, 412see also McDoNALD J C et al

GLANCY J J see DE KLERK N H et alGUNDMEYER H W see HUGHES JM et alGOLDOFTM et al: Nasal melanoma: correspondence, 767GoLNICK J see NELSON K et alGOMOLA K see BECHER H et alGONO E see BRUCH J et alGORDON C L et at: An improved instrument for the in vivo

detection of lead in bone, 637GoTo S see OGAWA Y et alGREENBERG M: Asbestos and cancer: history and public

policy: correspondence, 95GRIFiN M J see MAEDA S and GRIFFIN M JGRnFrrH D E see DODSON R F et alGROENENDAL H see NELEMANS P J et alGROESENEKEN D see VEULEMANS H et alGUBERAN E et al: Mortality and incidence of cancer among a

cohort of self employed butchers from Geneva and theirwives, 1008

GUtNEL P et al: Incidence of cancer in persons with occupa-tional exposure to electromagnetic fields in Denmark, 758

GURUNATHAN G see SENANAYAKE N et alGUSEV V A et al: Effect of quartz and alumina dust on genera-

tion of superoxide radicals and hydrogen peroxide by alveo-lar macrophages, granulocytes, and monocytes, 732

GuSTAVSSON P see EvANoFF B A et alGUTZWILLER F see HOTZ P et al

H

HAGMAR L et al: Cancer incidence and mortality in theSwedish polyurethane foam manufacturing industry, 537Incidence of cancer and exposure to toluene diisocyanate andmethylene diphenyldiisocyanate: a cohort based case-referentstudy in the polyurethane foam manufacturing industry, 1003see also FRUS L et at; PERSSON P et al

HAGUENOER J M see MAREZ T et alMOuLIN J J et al

HAKULINEN T R see KAUPPINEN T P et alHAMAGUCHI T see TAKEBAYASHI T et alHAMMAD Y Y see HUGHES J M et alHARABuCm I et at Circadian variations of acute toxicity andblood and brain concentrations of inhaled toluene in rats, 280see also KISHI R et al

HARRNGTON JM see GARDINER K et alHART T B see SENANAYAKE N et alHEDENSTROM H see MAIMBERG P et alHERNBERG S G see KAUPPINEN T P et alHEYER N J see CHECKOWAY H et alHIGASHI T see MOIuMOTO Y et alHIRATAM see OGAWA Y et alHJELM E W see IF A et alHOBBS M S T see DE KLERK N H et alHOGSTEDT C see EVANOFF B A et alHOLLAND R I see EuLINGSEN D G et alHONEYBOURNE D see GANNON P F G et alHORSTMAN S W see DANIELL W et alHORSTMANN V see JAKOBSSON K et alHORTE L-G, TOREN K: Smoking adjusted mortality due toasthma in a population of Swedish working women:correspondence, 575

HOSKERM E see CASE RAM et alHOSODA K see TAKEBAYASHI T et alHOTTER G see CARDENAS AHOTTER G see ROELS H et alHOTZ P et al: Serum laminin, hydrocarbon exposure, and

glomerular damage, 1104Hu H see WHITE R F et alHUANG H see CHEN R et alHUANG J et al: Comprehensive health evaluation of workers in

the ceramics industry, 112HUGHES JM et al: Follow up study of workers exposed to manmade mineral fibres, 658

HUILAN Z, ZHIMING W: Study of occupational lung cancer inasbestos factories in China, 1039

HuISMAN B see vAN S1TTERT N J et alHULTBERG B see ELLINGsEN D G et alHUNTER D see BuCKELIL M et alHUNTING K L, WELCH L S: Occupational exposure to dustand lung disease among sheet metal workers, 432

HUSTINX W N M et alt Systemic effects of inhalational methylbromide poisoning: a study of nine cases occupationallyexposed due to inadvertent spread during fumigation, 155

I

ICHIKAWA Y E see OGAWA Y et alIGISU H: Haemolysis of human erythrocytes by pen-

tachlorophenol and its suppression by albumin, 378IKEDA T see HARABUCHI I et al

KATAKURA Y et alKISHI R et al

INGLIS A see DYER J et alIPPOLITO FM see BISANTI L et alIVAIDI C see MAGNANI C et alIWATSUBO Y see DERRIENNIC F et al

1130

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Author Index

JACKSON J, JoNEs A H: Haemolytic anaemia in a case of occu-

pational asthma due to maleic anhydride: correspondence, 191

JADON N see MUIR D C F et alJAKOBSSON K et at: Mortality and cancer morbidity among

cement workers, 264

JARRHoiM B: Incidence of lung cancer by histological type among

asbestos cement workers in Denmark: corespondnce, 767JARup L, ELINDER C G: Incidence of renal stones among cad-

mium exposed battery workers, 598JARvHoLM B see SANDEN A et alJEDRYCHOWSKIW see BECHER H et alJEGADEN D see MOULIN J J et alJOHANSON G see EDLING C et al

WALLES S A S et alJOHANSSON A see CAMNER P et alJONATHAN G see CARPENTER R G et alJONES A H see JACKSON J and JONES A HJONES R N see HUGHES J M et alJONGENEELEN F J see VAN Rooij J G M et alJULIAN J see MUIR D C F et alJUNG D see MUTTRAY A et al

K

KATAKURA Y et at: Distribution of radioactivity from 1 4C-

formaldehyde in pregnant mice and their fetuses, 175see also KiSHI R et al

KAuPPINEN T P et at: Chemical exposures and respiratory

cancer among Finnish woodworkers, 143Kmo M see MORIMOTO Y et alKIELKOWSKI D see MURRAY J et alKIEMENEY L A L M see NELEMANS P J et alKILBURN K J et at:- Pulmonary effects of exposure to fine fibre-

glass: irregular opacities and small airways obstruction:correspondence, 863

KING W J: A potential cause of bladder cancer: correspondence,

380KiSHi R et at: Acute effects of trichloroethylene on blood

concentrations and performance decrements in rats andtheir relevance to humans, 470see also HARABUCHI I et al; KATAKURA Y et al

KIYOSAwA H see HARABUCHI I et alKJUUS H see ELLINGSEN D G et al

FANDREM S I et alKNUDSEN 0 see DANIELSEN T E et alKONIETZKO J see MuTTRAY A et alKORN T see NELSON K et alKORSGAARD B see RAFFN E et alKoZONO J see CHIAZzE L et alKusIAK R A et al: Mortality from lung cancer in Ontario

uranium miners, 920Mortality from stomach cancer in Ontario miners, 117

L

1LAMB D see Li XY et at

LANDRIGAN P J see McCoNNELL R et alLANDRO-OLSTAD M see ELLINGSEN D G et alLANE R E: The care of the lead worker (1949,6,125): editor's

choice, 193

LANGARD S see DANIELSEN T E et alLAPLANTE J J see DALPHIN J C et alLARSSON S see SANDEN A et alLATERRItRE B see MOULIN J J et alLAUwERYS R see HOTZ P et al

SWENNEN B et al

IAUWERYS R R see CARDENAs A et alROELS H et al

LAWTHER P J see WALLER R E et alLEANDERSON P see NEiJARI A et alLEE H S see NG TP et alLEE J: Sample size and power considerations to procure the

required number of subjects with a certain attribute: corres-pondence, 765CHIA K S: Estimation of prevalence rate ratios for crosssectional data: an example in occupational epidemiology:correspondence, 861see also GoLDovr M et al

LEINSTER P et al: An assessment of exposure to glutaraldehydein hospitals: typical exposure levels and recommendedcontrol measures, 107

LEONARD M see MouLIN J J et alLETOURNEUX M see CHOUDAT D et alLEwiN-SMrrH R G: Objective testing for vasospasm in thehand-arm vibration syndrome: correspondence, 381

LI X Y et al: Production of interleukin 1 by rat pleural leuco-cytes in culture after intratracheal instillation of crocidoliteasbestos, 90

LIDDELL F D see MCDONALD J C et alI LLTE F see DESCHAMPS D et alLIMING P, XuN W: Lymphocyte B and T cell subsets in

peripheral blood from patients with asbestosis, 183LINDBERG A see EDLING C et alLINET M S et al: Non-Hodgkin's lymphoma and occupation

in Sweden: a registry based analysis, 79LISON D see Swennen B et alLiss G M, TARLO S M: Toluene diisocyanate induced

asthma: outcome according to persistence or cessation ofexposure: correspondence, 1055

LOF A et at: Toxicokinetics of toluene and urinary excretion ofhippuric acid after human exposure to 2H8-toluene, 55

LOMONOSOVA 0 S see Gusev V A et alLUGTENBURG D see VAN SrTTERT N J et alLuKAS E see ktrKAkovA I et alLUKKONEN R A see KAUPPINEN T P et alLUNDBORG M see CAMNER P et alLUNDMARK B-O see LOF A et alLuo J-CJ see FISCHBEIN A et alLYNGE E see GUENEL P et al

RAFFN E et al

M

McCoNNELL R et al: Angiosarcoma, porphyria cutanea tarda,and probable chloracne in a worker exposed to waste oilcontaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 699

MCCREDIE M, STEWART J H: Risk factors for kidney cancer inNew South Wales. IV. Occupation, 349

MCDONALD A D see MCDONALD J C et alMcDoNALD D B see CASE R A M et alMCDONALD J C et al: Dust exposure and mortality in chrysotile

mining, 1910-75 (1980,37,1 1): editor's choice, 1058The 1891-1920 birth cohort of Quebec chrysotile minersand millers: mortality 1976-88, 1073

MCGRANN S see MCKENNA KM et alMCKENNA K M et al: An investigation into the acute vascular

effects of riveting, 160MCLAUGHLIN J K see LINETM S et alMAEDA K see YANO E et alMAEDA S, GRiFIN M J: Temporary threshold shifts in finger-

tip vibratory sensation from hand-transmittted vibrationand repetitive shock, 360

MAEHLE W see MUIR D C F et alMAGGINI M see BisANTi L et at

1 131

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Author Index

MAGNANI C et al: A cohort study on mortality among wives ofworkers in the asbestos cement industry in CasaleMonferrato, Italy, 779

MAHEU M F see DALPHIN J C et alMALKER H S R see LINET M S et alMALKUSCH W see BRUCH J et alMALMBERG P et at: Changes in lung function of granite

crushers exposed to moderately high silica concentrations: a12 year follow up, 726

MALo J-L see VANDENPLAS 0 et alMANCN A see MAGNANI C et alMAPP C E see VANDENPLAS 0 et alMAREZ T et al: Bronchial symptoms and respiratory function

in workers exposed to methylmethacrylate, 894MARINI F see MouuN J J et alMASSARDIER C see Moulin J J et alMASSCHELEIN R see VEULEMANS H et alMATCZAK W, CHMIELNICKA J: Relation between variouschromium compounds and some other elements in fumesfrom manual metal arc stainless steel welding, 244

MATSUNAGA C see YANo E et alMEDING B see NILsSON R et alMENTZER K: Pulmonary effects of exposure to fine fibreglass:

irregular opacities and small airways obstruction: corres-pondence, 863

MEREAU M see MOULIN J J et alMEULENBELT J see HUSTINX W N M et alMIDLAND THORACIC SocIETY RESEARCH GROUP see GANNONP F G et al

MIKOCZY Z see HAGMAR L et alMILTON R see BucKELLM et alMIRER F E, PARK R M: A case-control study of malignant and

non-malignant disease among employees of a fibreglassmanufacturing facility: correspondence, 287

MITRA S: A study of the health conditions of child workers ina small scale leather industry in Calcutta, 938

MIYAKE H see HARABUCHI I et alKATAKURA Y et alKISHI R et al

MONFORT C see DERRIENNIC F et alMONNET E see DALPHIN J C et alMONTGOMERY M R see REASORM J and MONTGOMERY M RMOORE F see CARPENTER R G et alMOREY C see WHITE R F et alMORGAN W K C: Coal mining, emphysema, and compensa-

tion revisited: forum, 1051see also MUIR D C F et al

MORIMOTO Y et al: Synergistic effects of mineral fibres andcigarette smoke on the production of tumour necrosis factorby alveolar macrophages of rats, 955

MORLAND T see ELLINGSEN D G et alMOSSMAN B T: Mechanisms of asbestos carcinogenesis and

toxicity: the amphibole hypothesis revisited: editorial, 673MOULN J J et al: A mortality study among mild steel and

stainless steel welders, 234see also CHAU N et al

MOULINM see MOULIN J J et alMOULTON L H see SEIXAS N S et alMUIR D C F. Bias: forum, 1122MUIR D C F et al: Prevalence of small opacities in chest radio-

graphs of nickel sinter plant workers, 428MULLER J see KUSIAK R A et alMULLOY K B et al: Use of chest radiographs in epidemiologi-

cal investigations of pneumoconioses, 273MUR JM see CHAUN et al

MOULIN J J et alMURRAY J et al: Cor pulmonale and silicosis: a necropsy based

case-control study, 544

MUSK AW see DE KLERK N H et alMUTTI A see CARDENAS A et al

ROELS H et alMUTTRAY A et al: Subclinical impairment of colour visionamong workers exposed to styrene: correspondence, 766

N

NEJARI A et al: Mineral fibres: correlation between oxidisingsurface activity and DNA base hydroxylation, 501

NELEMANS P J et al: Melanoma and occupation: results of acase-control study in The Netherlands, 642

NELSON K et al: Manganese encephalopathy: utility of earlymagnetic resonance imaging, 510

NETTERSTROM B see CLAUSEN J et alNEWHOUSE M L, THOMPSON H: Mesothelioma of pleura andperitoneum following exposure to asbestos in the Londonarea (1965,22,262): editor's choice, 769

NG T P et al: Further evidence of human silica nephrotoxicityin occupationally exposed workers, 907

NICKELS J I see KAUPPINEN T P et alNILSSON K see EDLING, C et alNILSSON R et al: Asthma, rhinitis, and dermatitis in workers

exposed to reactive dyes, 65NORDHAGEN H P see ELLINGSEN D G et alNoRDLINDER R see NILSSON R et alNORSTROM A see LOF A et alNUYTS GD see CARDENAS A et al

ROELS H et al

0

O'DONNELL J see DaniellW et alOGAWA Y et at: Latency of the Achilles tendon reflex for

detection of reduced functions of the peripheral nervous

system in workers exposed to lead, 229OGLE C J see RUNDLE E M et alOKAYAMA A see OGAWA Y et alOKUI T see KATAKURA Y et alOKUTANI H see HUANG J et alOMAE K see TAKEBAYASHI T et alOSTIGUY G see BtGrN R et alO'SULLVAN M see DODSON R F et al

p

PANNETT B see GARDNER M J et alSHORE R E et al

PANTIN C F A see GANNON P F G et alPARK R M see MIRER F E and PARK RMPARTANEN T J see KAUPPINEN T P et alPATRIS A see CHAU N et alPEARSON JT see CASE R AM et alPERNET D see DALPHIN J C et alPERRY K M A see BUCKELLM et alPERSSON P et al: Biological monitoring of occupational

exposure to toluene diisocyanate: measurement of toluene-diamine in hydrolysed urine and plasma by gas chromatog-raphy-mass spectrometry, 1111

PEZERAT H see NEJJARI A et alPHAM Q T see CHAU N et alPHOON W H see NG T P et alPISATI G et al: Toluene diisocyanate induced asthma: out-come according to persistence or cessation of exposure, 60:correspondence, 1055

PoLIo J C see DALPHIN J C et alPONTI A see BISANTI L et alPOOLE C J M: Seamstress's finger, 668

1132

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Author Index

POPE D see SoRAHAN T and POPE DPOWERS D see KILBURN K H et alPRATT D S, RASK-ANDERSEN A: Inhalation fever: a proposed

unifying term for febrile reactions to inhalation of noxioussubstances: correspondence, 287

PRICE R G see CARDENAS A et alROELS H et al

PRIESTLY B G see EDWARDS JW and PRIESTLY B GPROCHAZKA B see STrTKARovA I et alPROCTOR S see WHITE R F et alPULKKAIA E I see KAUPPINEN T P et alPYE I F see DYER J et al

R

RAFFIN E et al: Incidence of lung cancer by histological typeamong asbestos cement workers in Denmark, 85; corres-pondence, 767

RAMIS I see CARDENAS A et alROELS H et al

RAMPEN F H J see NELEMANS P J et alRASCHETTI R see BISANTI L et alRASK-ANDERSEN A see PRATr D S and RASK-ANDERSEN ARASKMARK P see GUENEL P et alRAYMOND L see GUBERAN E et alRAYMOND L W: Semen quality in welders exposed to radiant

heat: correspondence, 1055REASOR M J, MONTGOMERY M R: Hexachlorophene exposure

in a young patient with soft tissue sarcoma: correspondence,670

REBSTOCK E see CHAu N et alREHN B see BRUCH J et alREID G see MURRAY J et alREURE M see MOULIN J J et alREYGAGNE A see DESCHAMPS D et alRIBBENS P H see VAN SITrERT N J et alRIGAL L see MOULIN J J et alRITCHIE A C see KUSIAK R A et alROBERT G see MOULIN J J et alROBERTS R see MUIR D C F et alROBERTSON A S see GANNON P F G et alROBINS T G see SEIXAS N S et alROCCHI P S J see BOOGAARD P J et alROELEVELD N et al: Mental retardation and parental occupation:

a study on the applicability of job exposure matrices, 945ROELS H et at: Markers of early renal changes induced by

industrial pollutants. III Application to workers exposed tocadmium, 37see also CARDENAS A

Roos J see MUIR D C F et alROSELL6 J see CARDENAS A et alROSENBERG C R: An analysis of the reliability of self reportedwork histories from a cohort of workers exposed to poly-chlorinated biphenyls, 822

ROSENSTOCK L see DANIELLW et alROSSBACHER R see BOND G G and ROSSBACHER RROSSIGNOL C see CHOUDAT D et alROSSITER C E: Pulmonary effects of exposure to fine fibre-

glass: irregular opacities and small airways obstruction:correspondence, 381see also GARDINER K et al

RUIJTEN M W M M et al: Verification of effects on the ner-vous system of low level occupational exposure to CS2, 301

RUITER D J see NELEMANS P J et alRUNDLE E M et al: Analyses of the 1990 chest health survey of

china clay workers, 913RUSHTON L: Further follow up of mortality in a UnitedKingdom oil distribution centre cohort, 561

Further follow up of mortality in a United Kingdom oilrefinery cohort, 549

RUSSELLW see MCCONNELL R et al

S

SAETTA M see VANDENPLAS 0 et alSAKURAI H see TAKEBAYASHI T et alSALLE H J A see RuIJTEN MWM M et alSALLSTEN G et al: Decrease in mercury concentration in blood

after long term exposure: a kinetic study of chloralkali work-ers, 814

SAMET J M see MULLOY K B et alSANDEN A et al: The importance of lung function, non-malig-

nant diseases associated with asbestos, and symptoms aspredictors of ischaemic heart disease in shipyard workersexposed to asbestos, 785

SATO A see LOF A et alSATOH T see TAKEBAYASHI T et alSAVELKOUL T J F see HUSTINXWN M et alSCHIING R: Donald Hunter 1898-1978: Editor BJIM

1944-50: editorial, 5SCHILLING R S F: A university's contribution to occupational

health, 418Hazards of deep-sea fishing (1971,28,27): editor's choice,961

SCHINS P F R see BORM P J A and SCHINS P F RSCHOLTE R see NELEMANS P J et alSCHUTZ A see SALLSTEN G et alSEATON A: Coal mining, emphysema, and compensation

revisited: forum reply, 1051SEBASTIEN P see DANIEL H et alSEGNAN N see BISANTI L et alSEIXAS N S et al: Longitudinal and cross sectional analyses of

exposure to coal mine dust and pulmonary function in newminers, 929

SENANAYAKE N et al: An epidemiological study of the healthof Sri Lankan tea plantation workers associated with longterm exposure to paraquat, 257

SHERWOOD BURGE P see GANNON P F G et alSHIBATA E see HUANG J et alSHIRALI P see MAREz T et alSHORE R E et al: Ethylene oxide: an assessment of the epi-

demiological evidence on carcinogenicity, 971SILBERGELD E K see MCCONNELL R et alSKARPING G see PERSSON P et alSONG H see BRUCH J et alSONGW see BRUCH J et alSORAHAN T, POPE D: Mortality and cancer morbidity of

production workers in the United Kingdom flexiblepolyurethane foam industry, 528Mortality study of workers employed at a plant manufactur-ing chemicals for the rubber industry: 1955-86, 998

SPITZER W 0: Low back pain in the workplace: attainablebenefits not attained: editorial, 385

SPRINGER J see KUSIAK R A et alSQUIRE J R see CRUICKSHANK C N D and SQUIRE J RSTANESCU D see SWENNEN B et alSTEBBINS A see DANIELLW et alSTEENLAND K, STAYNER L: An epidemiological study of work-

ers potentially exposed to ethylene oxide: correspondence, 1 125STEENO 0 see VEULEMANS H et alSTETKAkOVA I et al: Somatosensory evoked potentials in work-

ers exposed to toluene and styrene, 520STEVENS B see CHURG A and STEVENS BSTEWART A, WITTS L J: Chronic carbon tetrachloride intoxi-

cation (1944,1,1 1): editor's choice, 7STEWART J H see MCCREDIE M and STEWART J H

1133

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Author Index

STocKs J M see DODSON R F et alSTOLTE H see CARDENAS A et al

ROELS H et alSTRAuss M E et al: Mortality experience of employeesexposed to 2-mercaptobenzothiazole at a chemical plant inNitro, West Virginia, 888

STROMBERG U see HAGMAR L et alSUGAR E R see RUNDLE E M et alSUNDBLAD B-M see MALMBERG P et alSWENNEN B et al: Epidemiological survey of workers exposed

to cobalt oxides, cobalt salts, and cobalt metal, 835

T

TAKEBAYASHI T et al: Evaluation of delta-aminolaevulinic acidin blood ofworkers exposed to lead, 49

TAKEUCHI Y see HUANG J et alTANAKA I see MORIMOTO Y et alTANAKA K see YANo E et alTARLO S M see Liss G M and TARLO S MTAYLOR P J: Individual variations in sickness absence

(1967,24,169): editor's choice, 865TAYLOR S A see CARDENAS A et al

ROELS H et alTECULESCU D see CHAu N et alTERRACiNI B see MAGNANI C et alTETA M J et al: Mortality study of ethylene oxide workers in

chemical manufacturing: a 10 year update, 704see also BENSON L 0 AND TErAM J

THIELEMANS N see HOTZ P et alTHOMASSEN Y see ELLINGSEN D G et alTHOMPSON H see NEWHOUSE M L and THOMPSON HTOAMAIN J P see MOUuN J J et alTocIYj J see ETEROvIC D et alTOREN K see HORTE L-G and TOKEN KTORNUNG G et al: Long term effects of alumina on compo-

nents of bronchoalveolar lavage fluid from rats, 172ToSON B see DALPHIN J C et alTRAN DINH Y see DESCHAMPS D et alTRENT L S see WONG 0 and TRENT L STRETHOWAN NW see GARDNSER K et alTRIEM S see CHOUDAT D et alTSANG P see FISCHBEIN A et al

U

UDUPIHLLE M see SENANAYAKE N et alULFBERG J see EDLING C et alURBAN P see krfrTAkovA I et alUSEL M see GUBRAN E et al

V

VAN DE LAAR R T H see HUSTINX WN M et alVAN HUFFELEN A C see HUSTINXW NM et alVAN SrITERT N J et al: A nine year follow up study of renal

effects in workers exposed to cadmium in a zinc ore

refinery, 603Application of the urinary S-phenylmercapturic acid test as

a biomarker for low levels of exposure to benzene inindustry, 460see also BOOGAARD P J et al

VANDENPLAS 0 et al: Occupational asthma and extrinsic alve-olitis due to isocyanates: current status and perspectives, 213

VANRooIJ J G M et al: Estimation of individual dermal andrespiratory uptake of polycyclic aromatic hydrocarbons in12 coke oven workers, 623

VATOLKINA 0 Y see GUSEV V A et al

VAUGHAN T see Goldoft M et alVELICHKOVSKY B T see Gusev V A et alVERBEEK A L M see NELEMANS P J et alVERBERK M M see RUIJTENMWMM et alVERWEY J C see HUSTINX W N M et alVEULEMANS H et al: Exposure to ethylene glycol ethers and

spermatogenic disorders in man: a case-control study, 71VICREY C see CHOUDAT D et alVIOSSAT M see MOULIN J J et alVrITALE J N see TETA M J et al

W

WAHLBERG J E see CAMNER P et alWAHRENDORF J see BECHER H et alWALLER R E et al: Air pollution in a city street (1965,22,128):

editor's choice, 677WALLES S A S et al: Exposure dependent increase in DNA

single strand breaks in leucocytes from workers exposed tolow concentrations of styrene, 570

WARSHAW R H see KILBURN K H et alWASS U see NILsSON R et alWASTIAUX A see DANIEL H et alWATKINS D K see CHIAZZE L et alWEBBER C E see GORDON C L et alWEi L see CHEN R et alWEILL B see CHOUDAT D et alWEILL H: Future of research into occupational lung disease:

editorial, 481see also HUGHES J M et al

WEINER J A see LINETM S et alWEIR D C see GANNON P F G et alWEISS N see GOLDOFr M et alWEISS W: Pulmonary effects of exposure to fine fibreglass:

irregular opacities and small airways obstruction: corres-

pondence, 1054WELCH L S see HUNTING K L and WELCH L SWELINDER H see HAGMAR L et al

JAKOBSSON K et alWELLER M P I: Asbestos and cancer: history and public

policy: correspondence, 671WHITE R F et al: Residual cognitive deficits 50 years after lead

poisoning during childhood, 613WILD P see MouLIN J J et alWINTER P D see GARDNER M J et alWITTS L J see STEWART A and WIrTS L JWOLFF C see CLAUSEN J et alWONG 0, TRENT L S: An epidemiological study of workers

potentially exposed to ethylene oxide, 308: correspondencereply, 1125

x

XUNW see LIMING P AND XUN W

y

YAMAOKA K see YANO E et alYANO E et al. Effect of smoking on pleural thickening in

asbestos workers, 898YOKOSAKI Y see MORIMOTO Y et al

z

ZANETTI R see MAGNANI C et alZEDDA S see PISATI G et alZHIMINGW see HUILAN Z and ZHIMINGWZIELHUIS G A see ROELEVELD N et al

1134

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British Journal ofIndustrial Medicine 1993;50:1135-1140

SUBJECT INDEX TO VOLUME 50, 1993Note: All conferences, notices and other announcements are under one heading: NOTICES

A

Achilles tendon reflex latency in detection of peripheral ner-vous system impaired from lead exposure, 229

Air pollutants, occupational, effect on histological types oflung cancer, 136

Air pollution in a city street: editor's choice, 677Airways obstruction, and fine fibreglass exposure: correspon-

dence, 381, 382, 863, 1054ALAD deficiency, see delta-Aminolaeuvulinic acid:

Aminolaevulinic acid dehydratase: PlumboporphyriaAlbumin suppression of haemolysis of erythrocytes by

pentachlorophenol, 378Allergens, contact, in registered cleaning agents for industrial

and household use, 1043Alumina

long term effects on components of bronchoalveolar lavagefluid from rats, 172and quartz dust, effect on generation of superoxide radicalsand hydrogen peroxide by alveolar macrophages, granulo-cytes, and monocytes, 732

Alveolar macrophages, production of TNF, synergistic effectsof mineral fibres and cigarette smoke, rats, 955

Amendment, 672delta-Aminolaevulinic acid, in blood of workers exposed to

lead, evaluation, 49Aminolaevulinic acid dehydratase deficiency in lead worker,

scenario for potential diagnostic confusion, 1119Amosite asbestos, absence in airways of non-smoking longterm workers exposed to asbestos, 355

Angiosarcoma, porphyria cutanea tarda, and probablechloracne, in worker exposed to waste oil contaminatedwith 2,3,7,8-tetrachlorodibenzo-p-dioxin, 699

Asbestosanalysis of ferruginous bodies in BAL from foundryworkers, 1032and cancer, history and public policy: correspondence, 95, 671carcinogenesis and toxicity, mechanisms, amphibolehypothesis revisited: editorial, 673cement workers

lung cancer incidence by histological type, Denmark, 85;correspondence, 767

mortality among wives, Casale Monferrato, Italy, 779chrysotile, revisited: correspondence, 862deliberate concealment of hazards, and bias: forum, 1122exposure

absence of amosite asbestos in airways of non-smokers,355and predictors of ischaemic heart disease, shipyard

workers, 785factories, occupational lung cancer, China, 1039lymphocyte subsets in subjects exposed to, changes in circu-lating natural killer cells: correspondence, 575mesothelioma of pleura and peritoneum following exposure,London area: editor's choice, 769workers

effect of smoking on pleural thickening, 898mortality from lung cancer (1955,12,81): editor's choice, 484

AsbestosisCT in early detection, 689and high resolution pulmonary computed tomography scansquantified by analysis of density distribution, 514lymphocyte B and T cell subsets in peripheral blood, 183

Asthmaoccupationaldue to isocyanates, 213; amendment, 672and haemolytic anaemia due to maleic anhydride: corre-

spondece, 191health, employment, and financial outcomes in workers

with, 491SHIELD scheme, West Midlands Region, UK, 791

smoking adjusted mortality, Swedish working women: corre-spondence, 575toluene diisocyanate induced, outcome according to persis-tence or cessation of exposure, 60: correspondence, 1055in workers exposed to reactive dyes, 65

B

B cell subsets in peripheral blood in asbestosis, 183BASIC program for sample size and power considerations

for number of subjects with certain attribute: corespondece,765

Battery workers, cadmium exposed, incidence of renal stones,598

Benzene, urinary S-phenylmercapturic acid test as biomarkerfor low levels of exposure, 460

Bias in attitude, and a 'blind eye' turned against hazards ofasbestos: forum, 1122

Bladder cancer, potential cause: correspondence, 380British Journal ofIndustrial Medicie, 50 years on: editorial, 1Bronchial symptoms and respiratory function, methyl-

methacrylate exposure, 894Bronchoalveolar lavage, analysis of ferruginous bodies,

foundry workers, 1032Bronchoalveolar lavage fluid, long term effects of alumina on

components, rats, 172Butchers, self employed, and their wives, mortality and inci-

dence of cancer, Geneva, 1008

C

Cadmiumexposed battery workers, incidence of renal stones, 598exposure in zinc ore refinery, renal effects, nine year followup study, 603markers of early renal changes, 37

Calcutta, child workers in small scale leather industry, healthconditions, 938

Canceramong workers in a Norwegian nitrate fertiliser plant, 647and asbestos, history and public policy: correspondence, 95,671and ethylene oxide exposure, 308: correspondence, 1125incidence and mortalityamong cohort of self employed butchers and their wives,

1135

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Subject Index

Geneva, 1008mercury vapour exposure, chloralkali industry, Norway,

875kidney, New South Wales, risk factors, occupation, 349morbidity, cement workers, 264morbidity and mortality polyurethane foam industrySweden, 537UK, 528

mortality, ethylene oxide workers, 317mortality and incidence among sewage workers, 653in persons with occupational exposure to electromagneticfields, Denmark, 758

Car body repair shop workers, neuropsychological perfor-mance and solvent exposure, 368: correspondence, 1126

Carbon black, respiratory health effects, survey of Europeancarbon black workers, 1082

Carbon disulphide, low level exposure, nervous system effects,301

Carbon tetrachloride, chronic intoxication (1944,1,11):editor's choice, 7

Carcinogenicity, effects of phosphorylation of chrysotile, 167Cement workers

mortality and cancer morbidity, 264see also Asbestos

Ceramics industry, comprehensive health evaluation ofworkers, 112

Cerebral blood flow, in solvent induced psycho-organic syn-drome, 325

Chemical exposures and respiratory cancer, Finnish wood-workers, 143

Chest health survey, china clay workers, 1990, analyses, 913Chest radiographs, in epidemiological investigations of pneu-

moconioses, 273Child workers, health conditions, small scale leather industry,

Calcutta, 938Chimney sweeps, mortality and incidence of cancer, Sweden,450

China, occupational lung cancer in asbestos factories, 1039China clay workers, 1990 chest health survey, analyses, 913Chloracne, probable, angiosarcoma, and porphyria cutanea

tarda, in worker exposed to waste oil contaminated with2,3,7,8-tetrachlorodibenzo-p-dioxin, 699

Chloralkali industry, cancer incidence and mortality, mercuryvapour exposure, Norway, 875

Chloralkali plant, mercury and selenium in workers previouslyexposed to mercury vapour, 745

Chloralkali workers, decrease in mercury concentration inblood after long term exposure, 814

Chlorinated hydrocarbons, effects on kidney and liver of expo-sure to low concentrations, 331

Chlorohydrin production workers, mortality due to pancreaticand lymphopoietic cancers, 710

Chlorophenoxy herbicides, potential carcinogenicity, 340Chromium compounds, and some other elements in fumesfrom manual metal arc stainless steel welding, relationbetween, 244

Chronic bronchitis, and farmer's lung, French dairy farmers,prevalence and risk factors, 941

Chrysotileminers and millers, 1891-1920 birth cohort, mortality1976-88, Quebec, 1073mining, dust exposure and mortality, 1910-75: editor'schoice, 1058phosphorylation, effects on pleuropulmonary fibrogenicityand carcinogenicity, 167

Chrysotile asbestos, revisited: correspondence, 862Cigarette smoke and mineral fibres, synergistic effects on pro-

duction ofTNF by alveolar macrophages, rats, 955

Circadian variations of acute toxicity and blood and brainconcentrations of inhaled toluene, rats, 280

Cleaning agents, registered, for industrial and household use,contact allergens, 1043

Coal mine dust exposure, and pulmonary function in newminers, 929

Coal minerswith early pneumoconiosis, decreased glutathione contentand glutathione S-transferase activity in red blood cells, 633emphysema, and compensation revisited: forum, 1-051pneumoconiosis, miners and ex-miners with and without,death rates, South Wales (1956,13,102): editor's choice, 577

Cobalt, inhalation by sensitised guinea pigs, effects on lungs,753

Cobalt oxides, cobalt salts, and- cobalt metal exposure, epi-demiological survey of workers, 835

Cognitive deficits 50 years after lead poisoning during child-hood, 613

Coke oven plant workers, retired, mortality, 127Coke oven workers, dermal and respiratory uptake of PAHs,623

Colour vision, subclinical impairment, workers exposed tostyrene: correspondence, 766

Compensation, coal mining and emphysema: forum, 1051Computed tomography in early-detection of asbestosis, 689Contact allergens in registered cleaning agents for industrialand household use, 1043

Copper miners, mortality from lung cancer, 505Cor pulmonale and silicosis, necropsy based case-control

study, 544Crocidolite asbestos, intratracheal instillation, and production

of IL-1 by pleural leucocytes in culture, rat, 90Cross sectional data, estimation of prevalence rate ratios for,example in occupational epidemiology: correspondence, 861

CS2, low level exposure, nervous system effects, 301Cutting oils, and skin cancer, engineering industry (1950,7,1):

editor's choice, 289

D

Dairy farmers, chronic bronchitis and farmer's lung, preva-lence and risk factors, France, 941

Deep-sea fishing, hazards: editor's choice, 961Denmark, lung cancer incidence by histological type among

asbestos cement workers, 85; correspondence, 767Dental technicians, self employed, respiratory symptoms, lung

function, and pneumoconiosis, Paris, 443Dermatitis, in workers exposed to reactive dyes, 65Diatomaceous earth industry, mortality among workers, 586DNA single- strand breaks, exposure dependent increase, in

leucocytes from workers exposed to low concentrations ofstyrene, 570

2,4-DP, potential carcinogenicity, 340Dust

exposure, and mortality, in chrysotile mining, 1910-75:editor's choice, 1058occupational exposure, and lung disease, sheet metal work-ers, 432

Dyes, reactive, asthma, rhinitis, and dermatitis in exposedworkers, 65

Dyestuff industry workmen, urinary bladder tumours(1954,11,75): editor's choice, 389

E

Electromagnetic fields, cancer incidence in persons with occu-pational exposure, Denmark, 758

1136

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Subject Index

Emphysema, coal mining, and compensation revisited: forum,1051

Encephalopathy, manganese, utility of early MRI, 510Engineering industry, skin cancer from use of mineral oil

(1950,7,1): editor's choice, 289Erythrocytes, haemolysis by pentachlorophenol, suppressionby albumin, 378

Ethylene glycol ethers, exposure, and spermatogenic disor-ders, case-control study, 71

Ethylene oxide, assessment of epidemiological evidence oncarcinogenicity, 971

Ethylene oxide workerscancer mortality, 317in chemical manufacturing, mortality study, 10 year update,704potentially exposed, 308: correspondence, 1125

Evoked potentials and cerebral blood flow, in solvent inducedpsycho-organic syndrome, 325

Extrinsic alveolitis, due to isocyanates, 213; amendment, 672

F

Farmer's lung, and chronic bronchitis, French dairy farmers,prevalence and risk factors, 941

Ferruginous bodies in BAL from foundry workers, analysis,1032

Fibreglass, fine, pulmonary effects of exposure, irregular opac-ities and small airways obstruction: correspondence, 381, 382,863, 1054

Fibreglass manufacturingmalignant and non-malignant disease among employees:correspondence, 287malignant and non-malignant respiratory disease. IIExposure assessment, 717

Fibres based on cellulose, need for standardised testing proce-dures: forum, 187

Fibrogenicity, pleuropulmonary, effects of phosphorylation ofchrysotile, 167

Fingertip vibratory sensation from hand-transmitted vibrationand repetitive shock, temporary threshold shifts, 360

Finland, woodworkers, chemical exposures and respiratorycancer, 143

Formaldehyde14C-labelled, radioactivity from, distribution in pregnantmice and their fetuses, 176exposure, British chemical industry, cohort study ofworkers, update, 827

Foundry workers, analysis of ferruginous bodies in BAL, 1032France, dairy farmers, chronic bronchitis and farmer's lung,

prevalence and risk factors, 941France (Lorraine), iron miners, lung functions, respiratorysymptoms, and subsequent mortality, 1017

Fumigation, inadvertent inhalational methyl bromide poison-ing, 155

G

Geneva, mortality and incidence of cancer among selfemployed butchers and their wives, 1008

Glomerular damage, hydrocarbon exposure and serumlaminin, 1104

Glutaraldehyde exposure in hospitals, assessment, typicalexposure levels and recommended control measures, 107

Glutathione, decreased content, and glutathione S-transferaseactivity, in red blood cells of coal miners with early pneu-moconiosis, 633

Granite crushers exposed to moderately high silica concentra-tions, lung function changes, 12 year follow up, 726

H

Haemolysis of erythrocytes by pentachlorophenol and its sup-pression by albumin, 378

Haemolytic anaemia, in occupational asthma, due to maleicanhydride: correspondence, 191

Hand-arm vibration syndrome, objective testing forvasospasm: correspondence, 381

Hexachlorophene exposure in young patient with soft tissuesarcoma: correspondence, 670

High resolution pulmonary computed tomography scansquantified by analysis of density distribution, and asbestosis,514

Hippuric acid, excretion after 2H8-toluene exposure, 55Hunter, Donald 1898-1978, Editor BJIM 1944-50: editorial, 5Hydrocarbon exposure, serum laminin, and glomerular dam-

age, 1104Hydrogen peroxide and superoxide radicals, generation by

alveolar macrophages, granulocytes, and monocytes, effectof quartz and alumina dust, 732

Hypersensitivity pneumonitis presenting as sarcoidosis, 497

Immune system, as target for subclinical lead related toxicity,185

Inhalation fever, proposed unifying term for febrile reactionsto inhalation of noxious substances: correspondence, 287

Insulation workers, lung function, 252Interleukin 1, production by pleural leucocytes in culture after

intratracheal instillation of crocidolite asbestos, rat, 90Iron miners, lung function, respiratory symptoms, and subse-

quent mortality, Lorraine (France), 1017Ischaemic heart disease, predictors, shipyard workers exposed

to asbestos, 785Isocyanates, causing occupational asthma and extrinsic alve-

olitis, 213; amendment, 672

K

Kidneycancer, New South Wales, risk factors, occupation, 349effects of chlorinated hydrocarbons, low concentrations,331

L

Laminin, serum, hydrocarbon exposure, and glomerular dam-age, 1104

Leadblood concentrations, misconceptions: forum, 1123in bone, improved instrument for in vivo detection, 637evaluation of delta-aminolaevulinic acid in blood of exposedworkers, 49exposure, and Achilles tendon reflex latency, in detection ofperipheral nervous system impairment, 229markers of early renal changes, 28poisoning during childhood, cognitive deficits 50 yearsafter, 613-related toxicity, subclinical, immune system as target, 185

Lead worker, care (1949,6,125): editor's choice, 193Leather industry, small scale, child workers, health conditions,

Calcutta, 938Leucocytesfrom workers exposed to low concentrations of styrene, expo-sure dependent increase in DNA single strand breaks, 570pleural, IL production in culture after intratracheal instilla-tion of crocidolite asbestos, rat, 90

1137

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Subject Index

Liver, effects of chlorinated hydrocarbons, low concentra-tions, 331

Low back pain in the workplace, attainable benefits notattained: editorial, 385

Lung cancerhistological types, effect of occupational air pollutants, 136incidence by histological type among asbestos cementworkers, Denmark, 85; correspondence, 767mortality

asbestos workers (1955,12,81): editor's choice, 484copper miners, 505uranium miners, Ontario, 920

occupational, in asbestos factories, China, 1039see also Respiratory cancer

Lung diseaseoccupational, future of research: editorial, 481sheet metal workers, and occupational exposure to dust,432

Lung functionin insulation workers, 252and non-malignant diseases associated with asbestos, pre-dictors of ischaemic heart disease, shipyard workers, 785pre-employment, at age 16 years, as guide to lung functionin adult life, 422respiratory symptomsand pneumoconiosis, among self employed dental techni-

cians, Paris, 443and subsequent mortality, iron miners, Lorraine

(France), 1017LymphocytesB and T cell subsets, in peripheral blood in asbestosis, 183of petroleum retailers, sister chromatid exchanges, 149subsets, in subjects exposed to asbestos, changes in circulat-ing natural killer cells: correspondence, 575

Lymphopoietic and pancreatic cancers, in chlorohydrin pro-duction workers, mortality, 710

M

Magnetic resonance imaging, in manganese encephalopathy,510

Maleic anhydride, causing haemolytic anaemia in occupa-tional asthma: correspondence, 191

Man made mineral fibres, workers exposed to, follow upstudy, 658

Manchester University, Chair of Occupational Health,1945-1993, 418

Manganese encephalopathy, utility of early MRI, 510Manual metal arc stainless steel welding, relation betweenchromium compounds and some other elements in fumes,244

MCPA, MCPP, potential carcinogenicity, 340Melanoma

nasal: correspondence, 767and occupation, results of case-control study in TheNetherlands, 642

Mental retardation and parental occupation, applicability ofjob exposure matrices, 945

2-Mercaptobenzothiazole exposure, mortality trends, chemicalplant, West Virginia, 888

Mercurydecreased concentration in blood after long term exposure,chloralkali workers, 814poisoning, chronic (1946,3,55): editor's choice, 97and selenium, in workers previously exposed to mercuryvapour at a chloralkali plant, 745

Mercury vapour exposure

chloralkali industry, cancer incidence and mortality,Norway, 875

relation between exposure related indices and neuro-logical and neurophysiological effects, 736markers of early renal changes, 17previous exposure, chloralkali plant, renal dysfunction, 881

Mesothelioma of pleura and peritoneum following exposure toasbestos, London area: editor's choice, 769

Methyl bromide poisoning, inhalational, systemic effects, 155Methylene diphenyldiisocyanate exposure, and cancer

incidence, polyurethane foam manufacturing industry,1003

Methylmethacrylate exposure, bronchial symptoms and respi-ratory function, 894

Mineral fibresand cigarette smoke, synergistic effects on production ofTNF by alveolar macrophages, rats, 955correlation between oxidising surface activity and DNAbase hydroxylation, 501exposure, biological indications and significance, workshop,Japan, November 1991: meeting report, 412man made, workers exposed to, follow up study, 658

Mineral oil, and skin cancer, engineering industry (1950,7,1):editor's choice, 289

Minersand ex-miners, with and without coalworkers' pneumoco-niosis, death rates, South Wales (1956,13,102): editor'schoice, 577stomach cancer mortality, Ontario, 117

Mortality1976-88, of 1891-1920 birth cohort of Quebec chrysotileminers and millers, 1073among wives of asbestos cement industry workers, CasaleMonferrato, Italy, 779cement workers, 264and dust exposure, in chrysotile mining, 1910-75: editor'schoice, 1058experience of employees exposed to 2-mercaptobenzothia-zole, chemical plant, Nitro, West Virginia, 888from lung cancer, uranium miners, Ontario, 920and incidence of cancer among cohort of self employedbutchers and their wives, Geneva, 1008and radiographic abnormalities, in crocidolite exposure, 902study of workers employed at plant manufacturing chemi-cals for the rubber industry, 1955-86, 998

N

Nasal melanoma: correspondence, 767Natural killer cells, circulating, changes, in subjects exposed

to asbestos: correspondence, 575Nephrotoxicity, silica, in occupationally exposed workers, fur-

ther evidence, 907Neuropsychiatric symptoms, increase after occupational expo-

sure to low levels of styrene, 843Neuropsychological performance and solvent exposure, carbody repair shop workers, 368: correspondence, 1126

New South Wales, kidney cancer, risk factors, occupation,349

Nickel sinter plant workers, prevalence of small opacities inchest radiographs, 428

Nitrate fertiliser plant, cancer incidence, Norway, 647Non-Hodgkin's lymphoma

exposure to ethylene oxide, 308: correspondence, 1125and occupation, Sweden, registry based analysis, 79

Norway, chloralkali industry, cancer incidence and mortality,mercury vapour exposure, 875

Notices, 95, 192, 288, 384, 576, 671, 768, 1056

1138

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Subject Index

0

Occupational Health, Chair at Manchester University,1945-1993, 418

Oil distribution centre cohort, further follow up of mortality,UK, 561

Oil refinery cohort, further follow up of mortality, UK, 549Ontario

miners, stomach cancer mortality, 117uranium miners, mortality from lung cancer, 920

Opacitiesirregular, pulmonary, and fine fibreglass exposure: corres-

pondence, 381, 382, 863, 1054small, prevalence in chest radiographs of nickel sinter plantworkers, 428

Organic solvents, occupational exposure as cause of sleepapnoea, 276

Osteoarticular disorders, evolution, as function of past heavyphysical work factors, 627 retired subjects living in Parisarea, 851

p

Pancreatic and lymphopoietic cancers, in chlorohydrin pro-

duction workers, mortality, 710Paraquat, long term exposure, tea plantation workers, epi-

demiology of health, Sri Lanka, 257Parental occupation and mental retardation, applicability of

job exposure matrices, 945Paris, respiratory symptoms, lung function, and pneumoco-

niosis, self employed dental technicians, 443Pentachlorophenol, and haemolysis of erythrocytes, suppres-

sion by albumin, 378Peripheral nervous system impairment, detection after lead

exposure by latency of Achilles tendon reflex, 229Petroleum retailers, sister chromatid exchange in lympho-

cytes, 149S-Phenylmercapturic acid, urinary test as biomarker for low

levels of exposure to benzene, 460Pleural leucocytes, IL-1 production in culture after intra-

tracheal instillation of crocidolite asbestos, rat, 90Pleural thickening, effect of smoking, asbestos workers, 898Plumboporphyria (ALAD deficiency) in lead worker, scenario

for potential diagnostic confusion, 1119Pneumoconiosis

chest radiographs in epidemiological investigations, 273coalworkers', miners and ex-miners with and without, deathrates, South Wales (1956,13,102): editor's choice, 577early, coal miners, decreased glutathione content and glu-tathione S-transferase activity in red blood cells, 633respiratory symptoms, and lung function, among selfemployed dental technicians, Paris, 443

Pneumonitis, hypersensitivity, presenting as sarcoidosis, 497Pollutants, industrial, markers of early renal changes. I

Application to workers exposed to mercury vapour, 17; IIApplication to workers exposed to lead, 28; III Applicationto workers exposed to cadmium, 37

Polychlorinated biphenyl exposure, reliability of self reportedwork histories from cohort of workers, 822

Polycyclic aromatic hydrocarbons, dermal and respiratoryuptake, 12 coke oven workers, 623

Polyurethane foam manufacturing industry, cancer morbidityand mortalitySweden, 537UK, 528

toluene diisocyanate and methylene diphenyldiisocyanateexposure, and cancer incidence, 1003

Porphyria cutanea tarda, angiosarcoma, and probable

chloracne, in worker exposed to waste oil contaminatedwith 2,3,7,8-tetrachlorodibenzo-p-dioxin, 699

Pre-employment lung function at age 16 years, as guide tolung function in adult life, 422

Pregnancy, distribution of radioactivity from 14C-formalde-hyde in pregnant mice and their fetuses, 176

Prevalence rate ratios, estimation, for cross sectional data,example in occupational epidemiology: correspondence, 861

Psycho-organic syndrome, solvent induced, evoked potentialsand cerebral blood flow, 325

Pulmonary effects of fine fibreglass exposure, irregular opaci-ties and small airways obstruction: correspondence, 381, 382,863, 1054

Pulmonary function, and coal mine dust exposure, newminers, 929

Q

Quartz and alumina dust, effect on generation of superoxideradicals and hydrogen peroxide by alveolar macrophages,granulocytes, and monocytes, 732

Quebecchrysotile miners and millers, 1891-1920 birth cohort, mor-tality 1976-88, 1073dust exposure and mortality in chrysotile mining, 1910-75:editor's choice, 1058

R

Radiant heat, semen quality in exposed welders:correspondence, 1055

Radiographic abnormalities and mortality in crocidolite expo-sure, 902

Renal changes induced by industrial pollutants, markers. IApplication to workers exposed to mercury vapour, 17; IIApplication to workers exposed to lead, 28; III Applicationto workers exposed to cadmium, 37

Renal dysfunction, previous mercury vapour exposure, chlo-ralkali plant, 881

Renal effects after exposure to cadmium in a zinc ore refinery,nine year follow up study, 603

Renal stones, incidence among cadmium exposed batteryworkers, 598

Repetitive shock, temporary threshold shifts, 360Respiratory cancerand chemical exposures, Finnish woodworkers, 143see also Lung cancer

Respiratory disease, malignant and non-malignant, in fibre-glass manufacturing. II Exposure assessment, 717

Respiratory function, and bronchial symptoms, methyl-methacrylate exposure, 894

Respiratory health effects of carbon black, survey of Europeancarbon black workers, 1082

Respiratory symptoms, lung function, and pneumoconiosis,among self employed dental technicians, Paris, 443

Rhinitis, in workers exposed to reactive dyes, 65Riveting, acute vascular effects, 160Rubber industry, plant manufacturing chemicals for, mortality

study of workers, 1955-86, 998

S

Sarcoidosis, hypersensitivity pneumonitis presenting as, 497Seamstress's finger, 668Selenium and mercury in workers previously exposed to mer-

cury vapour at a chloralkali plant, 745Semen quality, in welders exposed to radiant heat: correspon-

dence, 1055

1139

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Subject Index

Sewage workers, cancer, mortality and incidence, 653Sheet metal workers, occupational exposure to dust and lung

disease, 432SHIELD scheme, West Midlands Region, UK, to study occu-

pational asthma, 791Shipyard workers

cancer incidence, 1097exposed to asbestos, predictors of ischaemic heart disease, 785

Sickness absence, individual variations: editor's choice, 865Silica

lung function changes in granite crushers exposed to mod-erately high concentrations, 12 year follow up, 726nephrotoxicity, in occupationally exposed workers, furtherevidence, 907

Silicon carbide, toxicological investigationsinhalation studies, 797in vitro cell tests and long term injection tests, 807

Silicosis and cor pulmonale, necropsy based case-controlstudy, 544

Sister chromatid exchanges in lymphocytes of petroleumretailers, 149

Skin cancer, from use of mineral oil, engineering industry(1950,7,1): editor's choice, 289

Sleep apnoea, occupational exposure to organic solvents ascause, 276

Smokingadjusted mortality due to asthma, Swedish working women:correspondence, 575among fireglass workers: correspondence, 287effect on pleural thickening, asbestos workers, 898

Soft tissue sarcoma, and hexachlorophene exposure: correspon-dence, 670

Solvent exposure, neuropsychological performance, car bodyrepair shop workers, 368: correspondence, 1126

Solvent induced psycho-organic syndrome, evoked potentialsand cerebral blood flow, 325

Somatosensory evoked potentials in workers exposed totoluene and styrene, 520

Spermatogenic disorders, and exposure to ethylene glycolethers, case-control study, 71

Sri Lanka, tea plantation workers associated with long termparaquat exposure, epidemiology of health, 257

Steelmild, welders, cancer incidence, 1097mild and stainless, mortality study among welders, 234

Stomach cancer, mortality, Ontario miners, 117Styrene

exposure dependent increase in DNA single strand breaksin leucocytes of workers exposed to low concentrations, 570increase in neuropsychiatric symptoms after occupationalexposure to low levels, 843somatosensory evoked potentials in exposed workers, 520subclinical impairment of colour vision among exposedworkers: correspondence, 766

Subjects with a certain attribute, sample size and power con-siderations to procure required number, BASIC program:correspondence, 765

Superoxide radicals and hydrogen peroxide, generation byalveolar macrophages, granulocytes, and monocytes, effectof quartz and alumina dust, 732

Swedenchimney sweeps, mortality and incidence of cancer, 450non-Hodgkin's lymphoma and occupation, registry basedanalysis, 79

T

T cell subsets in peripheral blood in asbestosis, 183Tea plantation workers associated with long term paraquat

exposure, epidemiology of health, Sri Lanka, 257Temporary threshold shifts in fingertip vibratory sensationfrom hand-transmitted vibration and repetitive shock, 360

2,3,7,8-Tetrachlorodibenzo-p-dioxin, contaminated waste oil,angiosarcoma, porphyria cutanea tarda, and probablechloracne in exposed worker, 699

Title change to Occupational and Environmental Medicine, 1057Toluene 2H8, toxicokinetics of toluene and urinary excretion

of hippuric acid after exposure, 55Toluene

inhaled, circadian variations of acute toxicity and blood andbrain concentrations, rats, 280somatosensory evoked potentials in exposed workers, 520

Toluene diisocyanateexposure, and cancer incidence, polyurethane foam manu-facturing industry, 1003induced asthma, outcome according to persistence or cessa-tion of exposure, 60: correspondence, 1055occupational exposure, biological monitoring, 1111

Trichloroethylene, acute neurobehavioural effects, 470Tumour necrosis factor, production by alveolar macrophages,

synergistic effects of mineral fibres and cigarette smoke,rats, 955

U

Uranium miners, mortality from lung cancer, Ontario, 920Urinary bladder tumours, in workmen in dyestuff industry

(1954,11,75): editor's choice, 389

V

Vascular effects, acute, of riveting, 160Vasospasm, in hand-arm vibration syndrome, objective test-

ing: correspondence, 381Vibration, hand-transmitted, temporary threshold shifts, 360

W

Waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin, angiosarcoma, porphyria cutanea tarda, and proba-ble chloracne in exposed worker, 699

Weldersexposed to radiant heat, semen quality: correspondence, 1055mild and stainless steel, mortality study, 234of mild steel, and other shipyard workers, cancer incidence,1097

Welding fumes, relation between chromium compounds andsome other elements, 244

West Virginia, chemical plant, 2-mercaptobenzothiazole expo-sure, mortality trends, 888

Woodworkers, chemical exposures and respiratory cancer,Finland, 143

z

Zinc ore refinery, cadmium exposure, renal effects, nine yearfollow up study, 603

1140