observation and result

OBSERVATION AND RESULTS

The study entitled “Effect of panchatikta Taila Matra Basti in

the patients suffering from Katishula vis-a vis Lumbar Spondylosis.”

was planned to evaluate effect of Panchatikta Taila on the patient of

Katishula. For that Panchatikta Taila Matra Basti along with Madhu

was given to one group comprising 20 patients of Katishula for 9

days. This group of treatment was termed as Group A. To compare

the effect of Madhu in Matra Basti, another group comprising 20

patients of Katishula was given Panchatikta Taila Matra Basti for 9

days. This group was termed as Group B.

Prior to start of the study in both groups, patients selected for

study were closely observed for a period of two days. In this period of

observation detailed history of patients was evaluated as per Performa

of case record form mentioned in the ending of materials and methods.

In these two days, all investigations were carried out and these values

were termed as before treatment. As well as the status of the patient

was also recorded with respect to symptoms and signs found in the

patient of Katishula of this series.

After completion of duration all the required investigations of all

the patients from both groups were again done. All these values were

recorded and termed as after treatment values. The status of all the

94

symptoms and signs were also recorded after completion of treatment.

Thus the change in the status of symptoms, signs and investigations

were recorded. The history recorded in this study on case record form,

revealed the facts and findings, which are presented herewith in the

tabular form. Some of them are highlighted with the help of graphical

presentations.

TABLE-9

Table Showing Age-wise distribution of 40 patients of KATISHULA

Sr. No.

Age Group Group A Group B Total No. Patients

PercentageNo. of pts.

% No. of pts

%

1) Balyavasta (0-16yrs.)

00 00 00 00 00

2) Tarunavasta (17-40yrs.)

09 45 10 50 19 47.5

3) Praudhavasta (41-60 yrs.)

11 55 10 50 21 52.5

. Ayurvedic concept of age is somewhat different with respect to

modern science.Age group as described by Sharangdhara was

considered in this study. In the present study maximum number of

patients (52.5%) were from the praudha-Avastha of Age while, 47.5%

patients were from taruna avasta (Table 9).

95

TABLE-10

Table Showing Sex-wise distribution of 40 patients of KATISHULA

Sr. No.

Sex Group A Group B Total No. Patients


% No. of pts

%

1) Male 6 30 8 40 14 35

2) Female 14 70 12 60 26 65

Table-10 reveals that maximum numbers of patients (65%) were

female whereas 35% of patients were male.

TABLE-11

Table Showing Religion -wise distribution of 40 patients of

KATISHULA

Sr. No.

Religion Group A Group B Total No. Patients


% No. of pts

%

1) Hindu 19 95 18 90 37 92.5

2) Muslim 01 05 00 00 1 2.5

3) Christian 00 00 02 10 2 5.0

Table-11 data reveals that maximum number of patients (92.5%)

were from Hindu religion, followed by 5% from Christian religion

whereas 2.5% from Muslim religion.

96

TABLE-12

Table Showing Economical status of 40 patients of KATISHULA

Sr. No.

Economical status

Group A Group B Total No. Patients


% No. of pts

%

1) Poor 02 10 01 05 03 7.5

2) Middle class 18 90 18 90 36 90

3) Rich 00 00 01 05 01 2.5

90% of patients in Group A and 90% of Group B were found to

be Middle-class income group. However 10% from Group Aand 5%

from Group B were found to be Lower class group. While only 5% of

higher class noted from Group B. (Table 12)

TABLE-13

Table Showing Educational status of 40 patients of KATISHULA

Sr. No.

Educational status

Group A Group BTotal No. Patients

PercentageNo. of

pts.%

No. of

pts%

1) Uneducated 01 05 03 15 04 10

2)Educated up

to SSC09 45 07 35 16 40

3) HSC 04 20 03 15 7 17.5

4) Graduate 06 30 07 35 13 32.5

97

In this series 05% people from Group A and15% from Group B

were found to be uneducated. Remaining patients were educated up to

different level of education. In that 45% in Group A and 35% in Group

B were found to be educated up to HSC. While 30% in Group A and

35% in Group B, were found to be graduate people.

TABLE-14

Table Showing Chronicity of disease of 40 patients of KATISHULA

Sr. No.

Chronicity of disease


PercentageNo. of

pts.%

No. of

pts%

1) 0-1 yrs 09 45 08 40 17 42.5

2) 1-5 yrs 06 30 07 35 13 32.5

3) 5-10 yrs 04 20 04 20 08 20

4) <10 yrs 01 5 01 5 02 5

In this maximum patient (42.5%) have symptoms since last

1year back.32.5%have same symptom since 5 years.20% patients

have same complaint since 10 years and rest 5% since more than 10

years.

98

TABLE-15

Table Showing Marital status of 40 patients of KATISHULA

Sr. No. Family

History



% No. of pts

%

1) Unmarried 01 05 00 00 01 2.52) Married 18 90 19 95 37 92.5

3) Widow 01 05 01 05 02 05

4) Widower 00 00 00 00 00 00

In above table only 5% were unmarried, maximum i.e.90% in

Group A and 95% in Group B were married. Only 5% were widow in

each group

TABLE-16

Table Showing Dominant Rasa in Ahar of 40 patients of

KATISHULA

Sr. No. Dominant

Rasa in Ahar



% No. of pts

%

1) Madhur 12 60 10 50 22 552) Amla 12 60 15 75 27 67.5

3) Lavan 05 25 08 40 13 32.5

4) Katu 19 95 18 90 37 92.5

5) Tikta 08 40 08 40 16 40

6) Kashaya 03 15 01 05 04 10

99

Ayurveda bestowed the importance of diet having all six types of

Rasa.Most of the Ayurvedic physicians of ancient era opined that the

diet having six types of Rasa should be ingested. People may have the

habit of consuming one or two particular Rasas excessively and then

may produce diseases related to it.

It was revealed that 95%of peoples in Group As and 90% Group

B were having the habit of ingesting food having Katu rasa. Some of

them had having habit of taking excess Madhura and Amla Rasa, they

were 60% in Group A and 50% and 75% in Group B. Incidance of

Tikta,Kashay and Lavana rasa also noted as shown in the table 16.

TABLE-17

Table Showing Type of Food Ingested by of 40 patients of

KATISHULA

Sr. No. Type of

Food Ingested



% No. of pts

%

1) Vegetarian 06 30 08 40 14 35

3) Mixed 14 70 12 60 26 65

The above table shows that more patients were having mixed

diet (70% in Group A and 60% in group B).Rest of having Vegetarian

diet (30% in Group A and 40% in group B).

100

TABLE-18

Table showing dominant Guna in ahara by 40 patients of

KATISHULA

Sr. No. Dominant

Guna in Ahar



% No. of pts

%

1) Ushna 06 30 07 35 13 32.5

2) Shita 14 70 13 65 27 67.5

3) Laghu 14 70 12 60 26 65

4) Guru 06 30 08 40 14 35

5) Snigdha 08 40 09 45 17 42.5

6) Ruksha 12 60 11 55 23 57.5

7) Veg.oil 20 100 20 100 40 100

8) Ghee 03 15 05 25 08 20

In this study, maximum patients were taking shita and Laghu

guna pradhan ahara. All patients were used veg.oil in their ahara.

TABLE-19

Table Showing Vyasana of 40 patients of KATISHULA

Sr. No.

Vyasana



% No. of pts

%

1) Madyapana 01 05 02 10 03 7.52) Tobacco 05 25 07 35 12 303) Tea/Coffee 19 95 20 100 39 97.54) Smoking 01 05 03 15 04 105) None 01 05 00 00 01 2.5

101

In this study, maximum patients were addicted to bad habit. It

shows maximum patient was addicted to Tea or Coffee. Tobacco

chewing was next to it with 25% in Group A and 35% in Group B.

Smoking and Madyapana were 05% in Group A and 15%, 10% in

Group B respectively.

TABLE-20

Table Showing Type of Work done by 40 patients of KATISHULA

Sr. No.

Type of Work


PercentageNo. of

pts.%

No. of

pts%

1) Sedentary 06 30 08 40 14 352) Standing 03 15 03 15 06 153) Sitting 04 20 02 10 06 154) Labor 07 35 07 35 14 35

The type of work done by the patient is also as important as

Aahar concept narrated by the Acharya Charak. Therefore the history

of work done by patients was pinpointed.

It is observed that the standing type of work done by patients of

Katishula in the both groups was 15% and the sitting type of work done

by the patient’s was 20% in Group A and 10% in Group B as shown in

the table 20. The maximum patients 35% in the both groups was found

to be laborious worker. In the above study 30% in Group A and 40% in

Group B of patients having sedentary type of work

102

TABLE-21

Table showing Sara Parikshana by 40 patients of KATISHULA

Sr. No. Sara

Parikshana



% No. of pts

%

1) Avara 06 30 05 25 11 27.52) Madhyam 11 55 12 60 23 57.53) Pravara 03 15 03 15 06 15

In this study, maximum patients were Madhyam Sara (57.5%).

Only 15% patient’s were Pravara Sara as shown in table.

TABLE-22

Table Showing Doshaj Prakriti in 40 patients of KATISHULA

Sr. No.

Doshaj Prakriti


PercentageNo. of

pts.%

No. of pts

%

1) Vata-Pittaja 09 45 10 50 19 42.5

2) Pitta-Kaphaja 03 15 04 20 07 17.5

3) Kapha-Vataja 08 40 06 30 14 35

Prakruti parikshan is the basic concept of Ayurved and it has

much more importance in Chikitsa.In above table 45% of Group A and

50% of Group B constituted Vata-Pittaja type Prakriti.The incidence for

Pitta-Kaphaja was 15% and 20% patients of Group A and Group B

103

respectively. 40% and 30% patients of Group A and Group B

respectively in Kapha-Vataja type of Prakriti.

TABLE-23

Table Showing Samhanana of 40 patients of KATISHULA

Sr. No.

Samhanana


PercentageNo. of

pts.%

No. of

pts%

1) Avar 05 25 06 30 11 27.5

2) Madhyam 11 55 11 55 22 55

3) Pravara 04 20 03 15 07 17.5

TABLE-24

Table Showing Satva-Bala of 40 patients of KATISHULA

Sr. No.

Satva-Bala


PercentageNo. of

pts.%

No. of pts

%

1) Avar 06 30 05 25 11 27.5

2) Madhyam 11 55 12 60 23 57.5

3) Pravara 03 15 03 15 06 15

104

TABLE-25

Table Showing Vyayama Shakti Parikshana of 40 patients of KATISHULA

Sr. No.

Vyayama Shakti


PercentageNo. of

pts.%

No. of

pts%

1) Avar 04 20 03 15 07 17.52) Madhyam 11 55 11 55 22 553) Pravara 05 25 06 30 11 27.5

TABLE-26

Table Showing Akrititaha Parikshana of 40 patients of KATISHULA

Sr. No.

Akriti


PercentageNo. of

pts.%

No. of pts

%

1) Krisha 07 35 08 40 15 37.5

2) Madhyam 10 50 09 45 19 47.5

3) Sthula 03 15 03 15 06 15

TABLE-27

Table Showing Deshatah Parikshana of 40 patients of KATISHULA

Sr. No.

Deshatah


PercentageNo. of

pts.%

No. of

pts%

1) Anupa 10 50 08 40 18 45.5

2) Jangla 06 30 07 35 13 32.5

3) Sadharana 04 20 05 25 09 22.5

105

TABLE-28

Table Showing Ahar-Shakti Parikshana of 40 patients of KATISHULA

Sr. No.

Ahar-Shakti


PercentageNo. of

pts.%

No. of pts

%

A) Abhyavaharana Shakti1) Avar 04 20 03 15 07 17.52) Madhyam 14 70 12 60 26 653) Pravara 02 10 05 25 07 17.5B) Jaran-Shakti1) Avar 05 25 05 25 10 252) Madhyam 13 65 10 50 23 57.53) Pravara 02 10 05 25 07 17.5C) Agni1) Visham 08 40 06 30 14 352) Tikshna 03 15 02 10 05 12.53) Manda 02 10 03 15 05 12.54) Madhyam 07 35 09 45 16 40

Dashavidha – Parikshana :

All the patients included in this study were examined with

respect to Ashtavidha, Dashavidha, Strotasa etc. Parikshana.

Dashvidha parikshana such as Prakruti, Sara, etc. help to have the

idea regarding of the dominance of Bala, of the patients.

In this series Dvandva type of Prakruti was encounted which is

mention before.

Most of the patients are having Madhyam type of Samhanan

(55% of Group A and Group B as per Table- 23). In this study Satva

106

was also investigated. Maximum number patients (about 55 % of

Group A and 60%of Group B) having Madhyam type of Satva already

shown in Table – 24)

Vyamshakti is nothing but the work. A parameter which gives

idea about Deha Bala. In the Katishula, Bala of patients which depends

on Dhatu-Saratva is reduced. Maximum patients of this series had

Madhyam Vyam Shakti(55% in both group), which had been indicated

in table-25.

Examination of Agni:

Examination of status of Agni is one of the important factors, as

Proper Agni is essential for the metabolism. Therefore it is at most

important to have the idea regarding the status of Agni of patients of

Katishula. The patients registered; in this series were investigated with

respect to Abyavaran Shakti, Jaran Shakti. It was noted that 70%

patients in Group A and 60% in Group B had Madhyam Abhyavaran

Shakti, while that of 65% of Group A and 50% of Group B having

Madhyam type of Jaran shakti. Also it can be noted that 20% of Group

A and 25% of Group B patients having Pravara Abhyavaran shakti and

only 10% and 25% respectively having Pravara Jaran shakti. It means

that peoples of Katishula were more likely goes towards Mithya-ahar.

107

Examination of Sthulata Krishata exclusively principles of

management of Katishula, depends upon Sthulata and Krishata of

Patients. In this series 50% patients of treated, and 45% patients of

controlled having Madhayam Akruti; Krisha was noted in 35% and 40%

patients of Group A and Group B respectively. (Table – 26)

About 50% of Group A and 40% of controlled patients was found

to be residential of Anupa Desh, 30% and 35% patients of Group A and

Group B was found to be residential of Jangala Desh as per shown in

Table – 27.

108

TABLE-29

Showing Incidence of main Vyadhi Ghataka involved 40 patients of KATISHULA

Sr. No.

Vyadhi Ghatak involved


PercentageNo. of

pts.%

No. of

pts%

A) Dosha-Involved

1)Vata-Dominance

20100

20100

40 100

2)Pitta-Dominance

12 60 09 45 21 52.5

3)Kapha-Dominance

04 20 05 25 09 22.5

B) Dhatu-Involved1) Rasa Dhatu 06 30 05 15 11 27.52) Rakta Dhatu 11 55 13 65 24 60

3)Mamsa Dhatu

05 25 03 15 08 20

4) Meda Dhatu 03 15 04 20 07 17.5

5) Asthi Dhatu 20100

20100

40 100

6) Majja Dhatu 12 60 11 55 23 57.5

7)Shukra Dhatu

00 00 00 00 00 00

C) Strotas Involved1) Rasa-vaha 12 60 10 50 22 552) Rakta-vaha 09 45 09 45 18 453) Mamsa-vaha 05 25 05 25 10 254) Meda-vaha 03 15 03 15 06 15

5) Asthi-vaha 20100

20100

40 100

6) Majja-vaha 20100

18 90 38 95

Concept of Vyadhi in Ayurveda is unique, which deals with

Dosha, Dushya, Srotas and particular region on the body. Katishula is

generalized disease in which whole body is affected.

109

Incidence for Dosha dushti:

Incidence for involvement of Dosha was evaluated with the help

of Dosha-Vruddhi Laxanas. In this study 100% of patients in the both

groups exhibited dominance of Vata Dushti Laxanas. Dominance of

Pitta dushti was found in 60% in Group A and 45% in group B of

Katishula, while that Kapha dominance was found to be 20% and 25%

in Group A and Group B respectively. (Table 21)

Incidence for Dhatu Dushti:

In this study it was observed that Asthi Dhatu Dushti was

observed in all patients of both the groups. Mamsa Dushti was found in

25% of Group A and 15% of Group B of patients. 55% of Group A and

65% of Group B of patients is found to be Dushti in Rakta Dhatu also.

60% of Group A and 55% of Group B of patients is found to be Majja

Dhatu Dushti.

Involvement of Srotasa:

In this study Asthivaha Srotas were involved in all patients of

both the groups.100% and 90% of patients in Group A and Group B

was found to be Dushti in Majjavaha Srotas respectively.

110

45% in Raktavaha Strotas,25% in Mansavaha Strotas and 15%

in Medavaha Strotas Dushti were found in both group respectively.

TABLE-30

Table Showing Effect of Symptoms Score of 40 Patients of

Katishula

Sr. No.

Symptom

Group A Group B

BT ATDiffere

ncePercentage of Relief

BT ATDifference

Percentage of Relief

1 Katishula 46 16 30 65.21 48 25 23 47.91

2Akunchan Prasaranyoh Shula

36 10 26 72.22 37 16 21 56.75

3Pidanasahatva

38 11 27 71.05 38 16 22 57.89

4Shulasya Kala

31 11 20 64.51 36 14 22 61.11

5 Anidra 30 5 25 83.33 28 9 19 67.85

Effect of Therapy on symptoms Score:

It was observed that overall percentage of relief was more in

Group A than Group B. The symptoms such as katishala, Akunchan

Prasaranyoh Shula, pidansahatva, shulasya kala, anidra etc. were

studied in this series as described in Table

111

TABLE-31

Table Showing Effect on Symptoms of 20 Patients of Katishula of

Group A group by Wilcoxon-Matched –Pairs-Signed-Ranks Test

Sr.no

Symptom Mean SD SEd

Sum of All

Signed Ranks

No.of Pairs

Z P

1 KatishulaBTATDiff.

2.30.81.5

0.47020.52310.513

0.10520.117

0.1148210 20 3.919 <0.001

2. Akunchan Prasaranyoh

ShulaBTATDiff

1.80.51.3

0.52310.607

0.4702

0.1170.13580.1052

210 20 3.919 <0.001

3. PidanasahatvaBTATDiff

1.90.551.35

0.55250.60480.4894

0.12360.13530.1095

210 20 3.919 <0.001

4. Shulasya KalaBTATDiff

1.550.55

1

0.60480.60480.7255

0.13530.13530.1623

120 15 3.407 <0.001

5. AnidraBTATDiff.

1.50.251.25

0.5130.44430.6387

0.11480.09940.1429

171 18 3.72 <0.001

112

Statistical Analysis of the Effect of Therapy on Symptoms of

Katishula of Group A by Wilcoxon-Matched –Pairs Signed Ranks

Test:

Katishula: Sum of all signed ranks was 210.The number of pairs were

20. Z value was 3.9199, which was statistically very highly significant,

P<0.001 (Table-31)

Akunchan Prasaranyoh Shula: Sum of all signed ranks was 210.The

number of pairs were 20. Z value was 3.9199, which was statistically

very highly significant, P<0.001 (Table-31)

Pidansahatva :- Sum of all signed ranks was 210.The number of pairs

were 20. Z value was 3.9199, which was statistically very highly

significant, P<0.001 (Table-31)

Shulasya Kala: Sum of all signed ranks was 120.The numbers of pairs



Anidra: Sum of all signed ranks was 171.The numbers of pairs were


P<0.001 (Table-31)

113

TABLE-32

Table Showing Effect on Symptoms of 20 Patients of Katishula of

Group B by Wilcoxon- Matched –Pairs-Signed-Ranks Test

Sr.no

Symptom Mean SD SEdSum of All

Signed Ranks

No.of Pairs

Z P

1 KatishulaBTATDiff.

2.41.251.15

050260.71640.4894

0.11240.16030.1095

190 19 3.82 <0.001

2. Akunchan Prasaranyoh ShulaBTATDiff

1.850.81.05

0.81270.83350.394

0.18180.18650.0882

190 19 3.82 <0.001

3. PidansahatvaBTATDiff

1.90.81.1

0.71820.95150.5525

0.16070.21290.1236

171 18 3.723 <0.001

4. Shulasya KalaBTATDiff

1.80.71.1

0.76780.80130.5525

0.17180.17930.1236

171 18 3.723 <0.001

5. AnidraBTATDiff.

1.40.450.95

0.50260.60480.6048

0.11240.13530.1353

136 16 3.516 <0.001

114

Statistical Analysis of the Effect of Therapy on Symptoms of

Katishula of Group B by Wilcoxon - Matched –Pairs Signed Ranks

Test

Katishula : Sum of all signed ranks was 190.The number of pairs were


P<0.001 (Table-32)

Akunchan Prasaranyoh Shula: Sum of all signed ranks was 190.The

numbers of pairs were 19. Z value was 3.82, which was statistically

very highly significant, P<0.001 (Table-32)

Pidansahatva: Sum of all signed ranks was 171.The numbers of pairs



Shulasya Kala: Sum of all signed ranks was 171.The numbers of pairs



Anidra: Sum of all signed ranks was 136.The number of pairs were


P<0.001 (Table-32)

115

TABLE-33

Table Showing Comparison between two groups with respect to

Symptoms Score by Mann-Whitney test

Sr.no

Symptom R1 Mean U SDMean ± 1.96SD

Z P

1 Katishula 455 190 135 35.59120.25-259.75

1.53 >0.05

2.Akunchan

Prasaranyoh Shula

437 190 153 35.59120.25-259.75

1.32 >0.05

3. Pidansahatva 413 180 157 34.20112.96-247.032

0.65 >0.05

4.Shulasya

Kala270 135 120 19.55

96.682-173.31

0.741 >0.05

5. Anidra 344 144 115 28.9887.2-

200.800.983 >0.05

Comparison between two groups with respect to symptom score

was statistically evaluated by Mann-Whitney test. There is no

significant difference was found in two groups.

116

TABLE- 34

Sr. No.

Physical

Parameters

Mean ± SD Mean of Diff.

± SD

SEd t P

BT AT

1

Angle of Flexion (in deg.)

Group A

Group B

94.75 ± 10.696

90.25 ± 11.751

104.25 ± 11.728

97.5 ± 11.865

9.5 ±3.203

7.25 ± 3.795

0.716

0.849

13.255

8.537

<0.001

<0.001

2

Angle of Extension (in

deg)

Group A

Group B

19.25 ± 4.375

18.75± 4.8327

25 ± 4.588

25 ± 3.973

6.5 ± 2.350

6.25 ± 2.75

0.525

0.615

12.359

10.156

<0.001

<0.001

3

Distance Between Ground

And Middle Finger of Patient

(in cm)

Group A

Group B

19.45 ±4.8175

21.1 ± 5.702

15.3±5.212

17.15 ± 4.837

4.15 ± 1.496

3.95 ± 2.235

0.334

0.5001

12.396

7.8983

<0.001

<0.001

Table Showing Effect on Physical Parameters of 40 Patients of

KATISHULA

117

Effect of therapy on physical parameters was statistically

evaluated by Paired t test as follows.

Angle of Flexion: The mean Angle of flexion in Group A before

starting the treatment was 94.75 ± 10.696which increase up

to104.25±11.728.Increase in Angle of Flexion by 9.5 ±3.203 was tested

statistically by paired ‘t’ test, t was 13.255 which was very highly

significant, P<0.001(Table-34)

In the same manner Angle of Flexion in Group B also increased

by 7.25 ± 3.795 of which t was 8.537 and was very highly significant,

P<0.001 (Table-34)

Angle of Extension: Angle of Extension of Group A increased from

19.25 ± 4.375 to 25 ± 4.588. Increase in Angle of Extension by 6.5 ±

2.350 was statistically very highly significant because t was 12.359,

P<0.001(table-34)

In case of Group B Angle of Extension increased from 18.75 ±

4.8327 to 25 ± 3.973. Increase in Angle of Extension by 6.25 ± 2.75

was statistically very highly significant because t was 10.156, P<0.001

118

Distance Between Ground And Middle Finger of Patient: Distance

between Ground and Middle Finger of Patient of Group A reduced from

19.45 ± 4.8175 to 15.3 ± 5.212. Decrease in Distance between Ground

and Middle Finger of Patient by 4.15 ± 1.496 was statistically very

highly significant because t was 12.396, P<0.001(table-34)

In case of Group B Distance Between Ground And Middle

Finger of Patient reduced from21.1 ± 5.702 to 17.15 ± 4.837.Decrease

in Distance Between Ground And Middle Finger of Patient by 3.95 ±

2.235 was statistically very highly significant because t was 7.898,

P<0.001

119

TABLE- 35

Table Showing Effect on Haematological Parameters of 40

Patients of Katishula by Paired t Test

Sr. No

Haematological

Parameters

Mean ± SDMean of Diff.± SD

SEd t P

BT AT

1

Haemoglobin

Group A

Group B

11.685 ±

1.2209

11.755 ±

1.1865

11.895 ±

1.1264

11.99 ±

1.2809

0.21 ± 0.5004

0.235 ± 0.68

0.1119

0.1521

1.875

1.5447

>0.05

>0.05

2

ESR

Group A

Group B

28.5 ± 7.8639

30.25 ±

7.3044

26.75 ±

6.9953

28.8 ± 6.8333

1.75 ± 4.0246

1.45 ± 4.3222

0.9003

0.9669

1.9436

1.4995

>0.05

>0.05

3

Serum.Calcium

Group A

Group B

8.685 ±

0.825

8.23 ± 0.6449

9.0425 ±

0.6904

8.36 ± 0.6159

0.357 ± 0.8459

0.13 ± 0.3326

0.1892

0.0744

1.8890

1.7470

>0.05

>0.05

5

Serum.Alkaline

Phosphatage

Group A

Group B

63.69 ±

17.322

58.58 ±

3.876

62.1 ± 13.095

58.54 ±

4.153

1.591 ± 5.800

0.039 ± 2.32

1.297

0.520

1.225

0.07

>0.05

>0.05

120

Effect of Therapy on Hematological Parameters:

Hemoglobin: Hemoglobin slightly increased by 0.21 ± 0.5004 in Group

A, paired t was 1.875 and was insignificant. In Group B it was

increased by 0.235 ± 0.68. Paired t was 1.5447 which was also

insignificant. (Table - 35)

ESR: ESR decreased by 1.75 ± 4.0246 in Group A, paired t was 1.94

and was insignificant. In Group B it decreased by 1.45 ± 4.322. Paired t

was 1.4995 which was also insignificant. (Table - 35)

Serum Calcium: Sr.Calcium increased by 0.3575 ± 0.8459 in Group

A, paired t was 1.8890 and was insignificant. In Group B it was

increased by 0.13 ± 0.3326. Paired t was 1.7470 which was also

insignificant. (Table-35

Serum Alkaline Phosphatage: Sr.Alkaline Phosphatage decreased

by 1.591 ± 5.800 in Group A, paired t was 1.225 and was insignificant.

In Group B it was decreased by 0.039 ± 2.32. Paired t was 0.07 which

was also insignificant. (Table - 35)

121

TABLE-36

Table Showing Effect on Lipid profile Parameters of 40 Patients of

Katishula by Paired t Test

Sr. No

Lipid Profile

Parameters

Mean ± SDMean

of Diff.± SD

SEd t PBT AT

1

Cholesterol

Group A

Group B

178.69 ± 35.8741

180.43 ± 36.927

173.465 ± 36.29

172.5 ± 31.375

5.225 ± 8.2879

7.90 ± 12.720

1.8541

2.845

2.8180

2.77

<0.05

<0.05

2

Triglyceride

Group A

Group B

137.595 ± 80.222

136.64 ± 66. 7708

127.38 ± 73.32

126.975 ±

72.6947

10.215 ±

23.1718

9.67 ± 22.49

5.1838

5.0331

1.9705

1.9212

>0.05

>0.05

3

HDL

Group A

Group B

32.267 ± 5.7796

33.084 ± 6.2411

35.46 ± 6.9766

30.18 ± 4.90

3.193 ± 6.3364

2.89 ± 5.15

1.4175

1.154

2.2525

2.50

<0.05

<0.05

122

4

LDL

Group A

Group B

148.06 ± 36.58

147.483 ±

28.8153

153.03 ±

38.1890

144.0065 ±

29.277

4.969 ± 13.487

3.4765 ±

11.8874

3.0172

2.6593

1.6468

1.3072

>0.05

>0.05

5

VLDL

Group A

Group B

27.095 ± 15.5057

25.5455 ±

15.0714

25.222 ±

16.2808

23.9355 ±

11.7790

1.8725 ±

6.0494

1.61 ± 5.2828

1.3533

1.1825

1.3836

1.3615

>0.05

>0.05

Effect of Therapy on Lipid Prpfile Parameters:-

Cholesterol: Cholesterol of Group A decreased from 178.69 ±

35.8741 to 173.465 ± 36.2945.Decrease in cholesterol by 5.225 ±

8.2879, was statistically significant because t was 2.8180, P<0.05

(table-36)

In case of Group B cholesterol slightly decreased from 180.43 ±

36.92 to 172.5 ± 31.375.decrease in cholesterol by 7.90 ± 12.720 was

statistically significant because t was 2.77, P<0.05 (table – 36)

123

HDL: HDL of Group A increased from 32.267 ± 5.7796 to 35.46 ±

6.9766. Increase in HDL by 3.193 ± 6.3364 was statistically significant

because t was 2.2525, P<0.05 (table-36)

In case of Group B HDL decreased from 33.084 ± 6.2411 to

30.18 ± 4.90. Decrease in HDL by 2.89 ± 5.15 was statistically

insignificant because t was 2.50, P<0.05 (Table-36)

Triglyceride: Triglyceride of Group A decreased from 137.59 ± 80.222

to 127.38 ± 73.32. Decrease in Triglyceride by 10.215 ± 23.1718 was

statistically insignificant because t was 1.9705, P>0.05 (table-36)

In case of Group B triglyceride decreased by 136.64 ± 66.7708

was statistically insignificant because t was 1.9212, P>0.05 (table-36)

LDL: LDL increased by 4.969 ± 13.487 in Group A, paired t was

1.6468 which was insignificant. In Group B it increased by 3.4765 ±

11.8874. Paired t was 1.307 which was also insignificant. (Table - 36)

VLDL: - VLDL decreased by1.87 ± 6.0494 in Group A; paired t was

1.38 and was insignificant. In Group B it decreased by 1.61 ± 5.2858.

Paired t was 1.36 and was also insignificant. (Table - 36)

TABLE- 37

124

Table Showing Variance Ratio Test before Treatment of Physical

Parameters

Sr. No

Physical Parameters

Before Treatment SD

F Ratio PGroup A SD

Group B SD

1Angle of Flexion

10.696 11.751 1.20 >0.05

2Angle of

Extension4.375 4.832 1.21 >0.05

3

Distance Between

Ground And Middle Finger

of Patient

4.817 5.702 1.40 >0.05

Variance Ratio Test Before Treatment:-

Variance ratio for Angle of Flexion, Angle of Extension, Distance

between Ground and Middle Finger of Patient, presented in Table-37

showed that there was no significant difference between two groups

with respect to this physical parameters. Therefore further statistical

evaluation was done to see the difference between two groups with

respect to these characters only by unpaired t test

TABLE-38

Table Showing Variance Ratio Test before Treatment of

Lipid Profile Parameters

125

Sr. No

Lipid Profile Parameters

Before Treatment SD

F Ratio PGroup ASD

Group BSD

1 Cholesterol 35.874 36.927 1.059 >0.05

2 HDL 5.779 6.241 1.16 >0.05

Variance ratio for Cholesterol, HDL in table – 38 showed that

there was no significant difference between two groups with respect to

these lipid profile parameters. Therefore further statistical evaluation

was done to see the difference between two groups with respect to

these characters by unpaired t test.

TABLE-39

Table Showing Comparison between Two Groups by

Unpaired t Test

Sr. No

Parameters

Mean of Diff. ± SD

Sed. t PGroup A Group B

1. Cholesterol 5.225 ± 8.287 7.90 ± 12.720 3.39 0.78 >0.05

2. HDL 3.193±6.336 2.89 ± 5.15 1.825 0.16 >0.05

126

3.Angle of Flexion

9.5 ± 3.203 7.25 ± 3.795 1.01 2.227 <0.05

4.Angle of

Extention6.5 ± 2.350 6.25 ± 2.75 0.80 0.937 >0.05

5.

Distance Between

Ground And Middle Finger

of Patient

4.15 ± 1.496 3.95 ± 2.235 0.60 0.33 >0.05

Comparison between Two Groups:

Comparison between two groups were statistically done by

unpaired t’ test.

Angle of Flexion: Mean of difference in Group A was 9.5 ± 3.203

which was compared with that of mean of difference in Group B. It was

7.25 ± 3.795.Unpaired t was 2.227, P <0.05 which suggested that

difference of mean exhibited by Group A was significant. (Table-39)

Angle of Extension:- Mean of difference in Group A was 6.5 ± 2.350

which was compared with that of mean of difference in Group B. It was

6.25 ± 2.75.Unpaired t was 0.937, P >0.05 which suggested that there

was no significant difference of mean between two groups.(Table-39)

Distance between Ground and Middle Finger of Patient: - Mean of

difference in Group A was 4.15 ± 1.496 which was compared with that

of mean of difference in Group B. It was 3.95 ± 2.235.Unpaired t was

127

0.33, P >0.05 which suggested that there was no significant difference

of mean between two groups. (Table-39)

Cholesterol: - Mean of difference in Group A was 5.225 ± 8.287 which

was compared with that of mean of difference in Group B. It was 7.90 ±

12.720.Unpaired t was 0.78, P >0.05 which suggested that there was

no significant difference of mean between two groups. (Table-39)

HDL: - Mean of difference in Group A was 3.193 ± 6.3364 which was

compared with that of mean of difference in Group B. It was 2.89 ±

5.15.Unpaired t was 0.1660, P >0.05 which suggested that there was

no significant difference of mean between two groups. (Table-39)

Total Effect of Therapy:

Total effect of therapy has been evaluated in terms of cured, markedly

improved, improved and unchanged.

TABLE-40

Table Showing Total Effect of Therapy in 20 Patients of Katishula

of Group A.

Sr.No.

Ave.% of Relief in

Ave.% of Relief in

Total Total % of Relief

Remarks

128

Symptoms

Signs

1 11.53069 93.33333 104.864 52.43201 Markedly Improved2 16.85102 60 76.85102 38.42551 Improved3 26.76834 46.66667 73.43501 36.7175 Improved4 8.838555 50 58.83855 29.41928 Improved5 9.02232 93.33333 102.3557 51.17783 Markedly Improved6 13.59218 93.33333 106.9255 53.46276 Markedly Improved7 14.34815 90 104.3482 52.17408 Markedly Improved8 15.02229 100 115.0223 57.51115 Markedly Improved9 8.936694 50 58.93669 29.46835 Improved10 9.131983 50 59.13198 29.56599 Improved11 16.09553 100 116.0955 58.04777 Markedly Improved12 20.14396 30 50.14396 25.07198 Improved13 14.38409 100 114.3841 57.19204 Markedly Improved14 16.33155 100 116.3316 58.16578 Markedly Improved15 22.03878 50 72.03878 36.01939 Improved16 21.74125 90 111.7413 55.87063 Markedly Improved17 26.06156 76.66667 102.7282 51.36411 Markedly Improved18 22.05475 93.33333 115.3881 57.69404 Markedly Improved19 16.36823 40 56.36823 28.18412 Improved20 25.02518 40 65.02518 32.51259 Improved

TABLE-41


of Group B.

Sr.No.

Ave.% of Relief in

Symptoms

Ave.% of Relief in

Signs

Total Total % of Relief

Remarks

1 14.83455 90 104.8345 52.41727 Markedly Improved2 10.23479 90 100.2348 50.1174 Markedly Improved3 15.89428 90 105.8943 52.94714 Markedly Improved4 11.70406 40 51.70406 25.85203 Improved5 32.4335 20 52.4335 26.21675 Improved6 23.55416 36.66667 60.22083 30.11041 Improved7 15.66856 40 55.66856 27.83428 Improved

129

8 9.286239 100 109.2862 54.64312 Markedly Improved9 10.42266 100 110.4227 55.21133 Markedly Improved10 12.97731 90 102.9773 51.48865 Markedly Improved11 13.38216 90 103.3822 51.69108 Markedly Improved12 13.38523 90 103.3852 51.69261 Markedly Improved13 6.884963 50 56.88496 28.44248 Improved14 33.4733 16.66667 50.13997 25.06998 Improved15 13.01946 50 63.01946 31.50973 Improved16 11.49058 40 51.49058 25.74529 Improved17 6.772823 93.33333 100.1062 50.05308 Markedly Improved18 17.24505 86.66667 103.9117 51.95586 Markedly Improved19 19.5741 36.66667 56.24077 28.12038 Improved20 13.43026 36.66667 50.09693 25.04846 Improved

TABLE-42


Sr.No.Total

Effect of Therpy

Group A Group B Total

No. of Pts.

%No.of Pts.

%No. of Pts.

%

1 Cured 0 0% 0 0% 0 0%

2Markedly Improved

11 55% 10 50% 21 52.5%

3 Improved 09 45% 10 50% 09 47.5%

130

4 Unchanged 0 0% 0 0% 0 0%

In case of Group A 11 patients (55%) were markedly improved

and 09 patients (45%) were improved.

In case of Group B 10 patients (50%) were markedly improved and 10

patients (15%) were improved.

TABLE-43

Table Showing Comparison between Two Groups by Chi-Square

Test

Sr.No.

Group Improved Markedly improved

Total Chi-square value

1 Group A (O)=09 (O)=11 20

0.08

>0.05

(E)=9.5 (E)=10.5

2 Group B (O)=10 (O)=10 20

131

(E)=9.5 (E)=10.5

Comparison between two groups was statistically evaluated by

chi-square test. The value is 0.08 which was statistically insignificant

which suggested that there was no significant difference between two

groups with respect to therapy.

132

observation and result

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