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    Anatomy and Physiology

    MSK

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    Anatomical Terms

    Sagittal Plane vertical plane passing throughthe center of the body dividing it into right andleft halves

    Coronal plane imaginary vertical plane at right

    angle to the sagittal plane

    Horizontal or transverse plane at right anglesto both the median and coronal planes

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    Figure 1.

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    Terms related to movement

    Flexion movement that takes place in thesagittal plane, usually an anterior movement

    Extension - straightening of a joint, usuallytakes place in a posterior direction

    Abduction movement away from the midline

    Adduction movement towards the midline

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    Terms related to movement

    Rotation movement of a part of the bodyaround its long axis

    Medial rotation - anterior surface faces mediallyLateral rotation anterior surface faces laterally

    Circumduction combination of fl, ext, add, abd.

    Protraction to move forward

    Retraction to move backward

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    Terms related to movement

    Inversion sole faces medially

    Eversion - sole faces laterally

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    Skin

    Epidermis :

    a) stratum corneum responsible for the waterproof characteristics of the skin

    b) stratum lucidum present only in the sole

    and palm

    c) stratum granulosum water retention andheat regulation

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    Skin

    d) stratum spinosum protects the basal layer

    e) stratum basale/germinativum regenerativelayer

    Dermis contains network of blood vessels,lymphatics, nerve endings, collagen and elasticfibers

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    Figure 2. skin

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    Bone

    - Living tissue with a calcified extracellularcomponents that adapts to stress applied to it

    Development:

    membranous direct transformation of

    condensed mesenchyme

    endochondral formed by replacing pre-formed cartilage model

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    Bone

    Macroscopic appearance:

    compact bone - ivory surface layer of maturebone

    Trabecular bone/cancellous/spongy bone interior of mature bone

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    Bone

    Cellular components:

    Osteoblast bone builders

    Osteoclast bone sculptors, found in howships

    lacunae

    Osteocytes osteoblasts incorporated in thematrix of bone

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    Composition of bone

    Hydroxyapatite resp. for bone hardness

    - composed of calcium, phosphate, and carbonate

    - 70% of the weight of bone

    Type 1 collagen 90% of the organic component

    of bone

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    Haversian system

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    Regional classification of bones

    1. Axial bones

    skull

    - cranium and face 22

    - auditory ossicles 6

    - hyoid 1

    vertebrae 26 Ribs 24

    Sternum 1

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    Regional classificaation of bones

    2. Appendicular bones

    Upper limb 64 bones

    Lower limb 62 bones

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    Types of boneaccording to general shapeLong bones humerus, femur, fibula

    Flat bones skull bones, sternum,

    Short bones carpal bones

    Irregular bones vertebra, pelvis

    Pneumatic bones - sinuses

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    Clinical correlation

    Fracture break on the normal continuity of thebone

    May be open or close

    May be classified according to completeness ordisplacement

    SSx: abnormal mobility,crepitus, swelling,ecchymosis, deformity, pain, tenderness, mmspasm

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    Fracture Classification

    Open Fx Gustilo ClassificationType 1 1 cm wound or less

    Type 2 - >1 cm wound with moderate softtissue damage

    Type 3 Extensive soft tse damage andcrushing due to high velocity trauma

    A adequate coverage

    B bone exposed with periosteal strippingC Circulation disrupted; arterial repair

    required

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    Transverse

    Spiral

    Oblique

    Comminuted

    Displaced

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    Stages of fracture healing

    1. Hematoma formation begins within 24 hrs

    2. Granulation tissue formation proliferation ofyoung fibroblast, ingrowths of capillaries 24

    to 72 hrs

    3. Callus formation complex structure formed

    by the granulation tissue,osteoblastproliferation, at the end of this stage the twoends move as one but cannot withstand stress(3 14 days)

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    Stages of fracture healing

    4. Consolidation broken bone ends are bridged,there is already a well formed bone, 2 6 weeks

    5. Remodelling final stage of healing where thebroken bone fragments are absorbed (6 wks 2

    yrs)

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    Principles of fracture treatment

    Reduction (close or open) to regain alignment

    Fixation to maintain reduction and preventany harmful stress until union has occurred

    - external : POP, fiber glass, cast, braces

    - internal : screws, plates, IM nails

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    Principles

    Traction:

    1. skin traction done by means of adhesive orreinforced foam rubber strips and encircling

    elastic bandage- use when not more than 5 or 6 lbs pull isrequired

    Bucks traction used to exert traction in thelong axis of the lower limb with knee and hip innormal position

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    Principles

    Russel traction done for older children, madeup of rope and pulley arrangement with head

    halter for cervical injury and canvass girdle forpelvis

    Bryants traction for children below 3 yearsold; usually with femoral shaft fracture, hip inflexed position

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    Principles

    Skeletal traction

    - balanced skeletal traction thomas splint andpearson attachment

    - Cruthfield tong used for fracture of the

    cervical spine

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    Figure 3 tractions

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    Traction Apparatus

    WeightsShould hang free

    Must be securedAvoid bumping or knocking

    Should not be a pendulum

    Should not be removed unless ordered by attending

    or emergency

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    Ropes

    There should be no frayed spots or knots in the

    running lengthshould not drag on the bedclothes or the bed

    frame

    No ropes should rest against one another

    Pulleys. The rope should rest securely in thepulley grooves. Pulley clamps must be securely

    attached to the bed frame and must not bemoved unless ordered

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    Spreader Bars. The spreader bars shouldcause no pressure on adjacent skin areas

    Footplate. The footplate should maintain andsupport the foot in a neutral position, with no

    pressure on either side of the foot, the heel, orthe toes. It must not rest against the foot of thebed, as this interferes with the traction pull.

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    . Footplate. The footplate should maintain andsupport the foot in a neutral position, with nopressure on either side of the foot, the heel, orthe toes. It must not rest against the foot of thebed, as this interferes with the traction pull.

    . Trapeze. The trapeze should be suspendedfrom the overhead bar of the bed frame so thatthe patient can reach and grasp it without strain

    and without twisting out of proper alignment.

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    Hammocks, Slings, and Halters. Theseshould be free of wrinkles and cause no pressure

    on bony prominence or joints. If paddingmaterial is used, it must be clean, dry, and freeof wrinkles and crumbs.

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    Skeletal traction

    Always check the insertion sites for signs ofinfection

    Daily dressing

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    Castsa. Short leg cast--extends from below the knee to

    the base of the toes.

    b. Long leg cast--extends from the upper ormiddle thigh to the base of the toes.

    c. Short arm cast--extends from below the elbow

    to the palm.d. Thumb spica or gauntlet cast--extends from

    below the elbow to the palm and includes thethumb

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    Long arm cast--extends from axilla to palm, withthe elbow normally immobilized at a right angle.

    Walking cast--a short or long leg cast with arubber or metal walking device attached to thefoot.

    Body cast--encases the trunk.h. Shoulder spica cast--a body cast that encases

    the trunk, shoulder, and elbow.

    i. Hip spica cast--a body cast that encases thetrunk and one or both lower extremities

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    Care of new castExpose to air , should not be covered

    Handle a wet cast carefully

    Support the cast

    Instruct the patient on its care

    Elevate the involved extremity once cast is dry

    Check for sharp edgesCheck circulation

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    Once dry:

    Check for sharp edges

    Check for loose bits inside the cast

    Check circulation, nerve integrity

    Check for odor

    Check integrity of the castPt education

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    After cast removalSupport the extremity

    Encourage exercise/use of extremity

    Avoid vigorous attempts to remove dead skincells, crusted exudates

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    Ambulatory aidsCrutches inc. base of support,moderate degree

    of stability, relieve weight bearing on the lower

    extremities

    Measurement : subtract 16 inches from the

    patients height, alt: 2 inches below axilla to apoint 6 inches in front and 2 inches lateral to thefoot, supine: axilla to a point 6 8 inches lateralto the heel

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    Ambulatory AidsCanes widen base of support, provide limited

    stability and unweighing (30%)

    Measurement: greater trochanter to a point 6inches to the side of toes

    Types: standard cane, quad cane

    Gait : held in the hand opposite the involvedextremity, cane and involved extremity advencedtogether, followed by uninvolved

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    Ambulatory aidsForearm crutches: the cuff should cover the

    proximal third of the forearm, about 1 1and a

    half inches below the elbow

    Axillary crutches: provide increased trunk support

    over forearm crutchesMay be difficult to use in small areas

    Prolonged leaning on the axillary bar can resultin vascular or nerve damage

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    Ambulatory aidsForearm crutches: have forearm cuff and a hand

    grip

    Provide less stability but increased ease ofmovement

    Frees hand for use without dropping the crutch

    Forearm platform cruthches used for patientswho cannot bear weight through their hands

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    Ambulatory AidsWalkers:

    -widen base of support

    - provide increased lateral and anterior stability

    - can reduce weight bearing on one or both LE

    - frequently prescribed for patients with

    debilitating conditions, poor balance, or lowerextremity injury when use of crutches isprecluded

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    Ambulatory aidsTypes:

    Folding collapsible, mobility in community,

    carsRolling available with either two or four

    wheels , facilitates walking as a continues

    movementReciprocal walker hinged, allows advancement

    of one side of walker one at a time

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    Ambulatory aidsStair climbing walker has two posterior

    extensions and additional hand grips off of the

    rear legs for use on stairsHemi walker modified for use with one hand

    only, hand grip is located in center front ofwalker

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    Sample ambulatory aids

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    Gait patternsWeight bearing status:

    Non- weight bearing

    Partial weight bearing

    Full weight bearing

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    Gait patternsFour point gait

    Indication: weakness in both legs or poor

    coordinationPattern sequence: left crutch, right foot, right

    crutch, left foot

    Advantages: excellent stability, always have 3 pt

    contact with the ground

    Disadvantages: slow walking speed

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    Gait patternsThree - point gait

    Indication: Inability to bear weight on one leg

    Pattern sequence: first move both crutches andthe weaker limb forward, then bear all your weightdown through the crutches, and move theunaffected leg forward

    Advantage: eliminates all weight bearing on theaffected leg

    Disadvantage: good balance is required

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    Gait patternTwo point gait

    Indication: weakness in both legs or poor

    coordinationPattern sequence: L crutch and R foot

    together,then R crutch and L foot together

    Advantage: faster than 4 point gait

    Disadvantage; may be difficult to learn the pattern

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    Gait patterns

    Swing through gaitIndication: inability to fully weight bear on both

    legs

    Pattern sequence: advance both crutches forward

    then while bearing all weight down through bothcrutches, swing both legs forward at the same timepast the crutches

    Advantage: fastest gaitDisadvantage: energy consuming, requires good

    UE strenght

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    Gait patternSwing to gait

    Indication: patients with weakness of both lower

    extremitiesPattern sequence: same as swing through but legs

    are not brought forward past the crutches.

    Advantage: easy to learn

    Disadvantage: requires good UE strenght

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    Gait patternsTripod gait

    Indication: initial pattern for patients with

    paraplegia learning to do swing to gait patternPattern sequence: advance L crutch, then right

    crutch, then drag both legs to the crutches

    Advantage: provides good stability

    Disadvantage: very energy consuming

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    Gait patternsStairs: good go to heaven, the bad go to hell

    Guarding:

    Level surfaces: stand slightly behind and to oneside , typically on the involved side

    Stairs: below the patient

    Ascent: behind and on the involved side

    Descent: in front and on the involved side

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    JointsSite where two or more joints meet

    Classification:

    Fibrous: joined by fibrous tse, very littlemovement , ex: sutures, inf. tibiofibular jt.

    Cartilaginous: may be primary or secondary

    Primary if the bones are united by a plate or bar ofhayline cartilage e.g.: union between epiphysis anddiaphysis

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    Secondary if bones are united by fribrocartillage

    e.g.: symphysis pubis

    Synovial Joint joint cavity lined by synovium,posses joint capsule, surfaces lubricated by

    synovial fluid

    types: hinge, ball and socket, saddle jt, ellipsoid,condyloid, pivot, plane jt

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    Type of synovial jointPlane : articular surfaces are flat or almost flat.

    - Sternoclavicular and acriomioclavicular jt

    Hinge : resemble hinge of a door

    - elbow, knee, ankle

    Pivot : central bony pivot surrounded by a bonyligamentous ring

    - Atlantoaxial and sup. Radioulnar jts

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    Condyloid : have two distinct convex surfaces

    that articulate with two distinct concave surfaces- MCP jt

    Ellipsoid : elliptical convex articular surface thatfits into an elliptical concave surface

    - Wrist jointSaddle joint : surfaces are reciprocally concave-

    convex. Example CMC of the thumb

    Ball and socket shoulder and hip

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    Types of joint

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    ArthritisInflammation of the joint

    Non inflammatory idopathic, posttraumatic,congenital

    Inflammatory most common is RA

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    Rheumatoid arthritisSym. Inflammatory arthritis involving small and

    large jts of at least 6 wks duration

    Diagnostic criteria:

    Morning stiffness

    Arthritis of at least 3 areas lasting greater than 6wks

    Involvement of hand joints > 6wks

    Must be symmetrical

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    Rheumatoid nodules

    RF (+)

    Xray evidenceAt least 4/7 to make a diagnosis

    Commonly affected jts : wrists, MCP, PIP, ankle,mtp, knees, shoulder, hips, elbow

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    Systemic manifestations:Anorexia, weight loss, fatigue

    Bouchards node osteophyte formation aroundPIPHeberdens node enlargement of DIPOpera glass hand severe destruction and

    resorption of synovial jt folded telescopeappearancePeripheral neuropathies mild and in the elderlyScleritis, episcleritis

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    ManagementAspirin, salicylates

    DMARDS gold, methotrexate, plaquenil

    Rehabsurgery

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    OsteoarthritisA form of chronic arthritis found in the middle

    aged and elderly

    Characterized by degenerative changes in thearticular cartillage and osteophyte formation

    Primary no underlying cause

    Secondary result of antecedent dse/injury

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    Prevalence:M>F - M - >45 y.o.F=M in generalSSx:Early stage :

    Stiffness of 1 or more joints associated with achingpainSlight enlargement of the affected jts which may be

    slightly tender about the margins

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    Bony enlargement of the DIP one of thecommonest sign

    Late stage LOM and disability

    Pain

    Jt malalignmentCrepitation

    Jt locking esp knees

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    Early fatigue

    Management

    General measures:

    Rest, weight reduction, brief ROM exercises

    non- weight bearing

    Drug therapy non specific, ASA drug of choice

    Rehab

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    Crystalline Arthropathies

    Gout - monosodium urate

    Pseudogout calcium pyrophosphate

    Manifestation:

    Abrupt onset, very painful, swollen, warm andtender joints may awaken sleep

    Mild attacks resolve spontaneously 1 to 2 days

    Severe attacks may last for a weekIn pseudogout may last for a month

    Attacks may be provoked by trauma, currentillness

    Labs elevated ESR, leukocytosis

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    Usually monoarticular

    Most common site 1st MTP but ca also involve

    the ankles, knees, wrist, fingers, elbows

    In pseudogout most common - knee

    Elbows, wrist, ankle, shoulder, hip

    Treatment of choice indomethacin 75 100mg, then 50 mg q 6

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    Seronegative spondyloarthropatiesAnkylosing spondylitis HLA B27

    Psoriatic arthritis

    Inflammatory bowel dseReiters dse

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    MuscleFunctional unit is the sarcomere

    Type of fibers:

    Type 1 or slow twitch muscles:

    - aerobic

    - fatigue resistant- high oxidative enzymes low in myosin ATPaseactivity

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    Type 2 or fast twitch muscle

    Anaerobic

    Prone to fatigue

    High in glycolytic enzyme and myosin ATPase

    activity

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    Sarcomere

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    Skeletal MuscleEach muscle fiber is multinucleate and behaves

    as a single unit. It contains bundles of myofibrils

    surrounded SR and invaginated by transversetubules

    Thick filaments present in the A band

    Contains myosin

    Each myosin molecule has 2 heads attached to asingle tail. The heads bind ATP and actin

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    Thin filaments are anchored at the z lines

    Present in the I bands

    Contain actin, troponin, and tropomyosin

    Troponin- a regulatory protein, a complex of threeglobular proteins

    Troponin T attaches to tropomyosin

    Troponin I inhibits interaction between actin andmyosin

    Troponin C avidly binds to calcium

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    Contraction

    1. Action potentials in the muscle cell membraneinitiate depolarization of the T tubules

    2. Depolarization of the T tubules opens Carelease channels in the SR

    3. Increase intracellular calcium

    4. Calcium binds to troponin C

    5. Myosin heads interact with actin filaments6. relaxation

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    Isometric contraction generation of tensionwithout shortening

    Isotonic contraction shorten at a constantafterload

    Atrophy decrease in muscle cell size

    Hypertrophy increase in muscle cell size

    Hyperplasia increase in the number of musclecells

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    MMT0 (zero) no muscular contraction

    1 (trace) a barely detectable flicker or trace ofcontraction

    2 (poor) active movement, gravity eliminated

    3 (fair) active movement against gravity

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    4 (Good) active movement against gravity andsome resistance

    5 (Normal) active movement against fullresistance

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    Duchenne Muscular DystrophyMost common and most disabling of the

    muscular dystrophies

    Defect of the X chromosome at the Xp21 locusBegins in early childhood with relatively

    progressive course

    Muscle weakness is obvious at the age 4 -5

    Death usually during adolescence seldomsurvive beyond 25 y.o.

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    Common cause of death resp infection

    Usually wheelchair bound by 10 -12

    SSx:Pseudohypertrophy of calf muscle

    Lordotic posture, protruded abdomen

    Waddling gait

    Gower sign

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    Myasthenia gravisAn autoimmune disorder characterized by

    weakness and execessive faigability often

    confined to ocular,palatal,or pharyngeal muscleF>M

    Destruction of Ach receptors

    Most common SSx ptosis, diplopia, dysphagia,dysarthria, weakness

    Later choking, nasal regurgitation

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    Nasal speech, hanging jaw sign

    Trident tongue one central and two

    longitudinal furrows in the tongue

    Management anticholinesterase ex.Neostigmine, pyridostigmine

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    Head and NeckSkull bones of the head, face, mandible

    Cranium head and face

    Calvaria bones of head onlyLayers of the SCALP:

    Skin

    subCutaneous tissue

    Aponeurosis

    Loose areolar tissue

    periosteum

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    Areolar space dangerous space, infections mayspread from scalp to meninges via the emissary

    veinsMuscles of facial expression supplied by the

    facial nerve

    Muscles of mastication supplied by yourtrigeminal nerve

    Extraoccular muscles supplied by cranial nervesIII, IV, VI

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    Eye closure muscles supplied by Cranial nerve7 (that is why eyelids lag in Bells palsy)

    Eye opening cranial nerve 3

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    Back and SpineMade up of 33 vertebrae

    7 cervical

    12 thoracic5 lumbar

    5 sacral

    4 coccygeal

    28 inches in length, 4 curves on lateral view

    Lordosis,kyphosis

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    Parts of a typical vertebra

    Body weight bearing portionPedicle short and thick posterior projections of

    the body

    Lamina flat part that unites the pedicles

    Arch formed by the lamina and pediclesTransverse process arise at the jxn of pedicle

    and lamina

    Spinous process posteriorly directed processfrom midpoint of lamina

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    The vertebra

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    Cervical vertebrae1st, 2nd, 7th are atypicalGen. characteristics :

    Has transverse foramen in the transverseprocessesBifid spinous processesSmall vertebral bodies

    Atlas no body and spinous processAxis odontoid processVertebra prominens - landmark

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    Thoracic VertebraePresence of costal facets

    Heart shape body

    Spinous process long and inclined downwards

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    Lumbar vertebraLarge size largest and strongest

    Body is kidney shape

    Short spinous processPresence of mamillary process

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    CorrelationPotts dse TB of the spine

    Commonly seen in Children below 10 yrs old

    Lower thoracic and upper lumbarUsually affects the vertebral body leads to

    vertebral collapse and gibbus formation

    MX : anti tb drugs for up to two years

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    Disc Herniation90% occurs at the L4 L5, L5-S1 level

    Common 30 50 y.o

    SSx Recurrent episodes of back pain and pain in the

    lower leg

    Prolonged sitting/standing aggravates the pain

    Sciatic pain

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    Treatment:

    Laminectomy

    Laminotomyrehab

    Sho lder

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    ShoulderBall and socket joint

    Commonly dislocated anteriorly

    Rotator cuff

    Supraspinatus

    InfraspinatusTeres minor

    Flexion: ant. Fibers of deltoid

    Extension: teres major

    Abduction: deltoidsAdduction: pectoralis

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    ElbowHinge or ginglymus joint

    Nursemaids elbow common 6 years old and

    belowFlexion: biceps brachi, brachialis,

    brachioradialis

    Extension: triceps brachi and anconeus

    Supination: supinator, biceps

    Pronation: pronator teres

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    Wrist JointCondyloid or ellipsoid joint

    Carpal bones:from lateral to medial, proximal to

    distal rowScaphoid (most commonly fractured), lunate

    (most commonly dislocated), triquetrum, pisiform(smallest)

    Trapezium, trapezoid, capitate, hamate

    Hand

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    Hand

    Thenar emminence: copmosed of the muscles,abductor pollicis brevis, flexor pollicis brevis,opponens pollicis

    Hypothenar eminence : abductor digiti minimi,flexor digiti minimi, opponens digiti minimi

    All intrinsic muscles of the hand are supplied by

    the ulnar nerve except AFOLS (thenar musclesand lumbricals 1 and 2) which is supplied by themedian nerve

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    HandFlexion of PIP: flexor dig. Supeficialis

    Flexion of DIP: flexor dig. Profundus

    Radial nerve injury: wrist drop

    Ulnar nerve: claw hand

    Median nerve: ape hand

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    hipBall and socket joint

    Most commonly dislocated posteriorly

    Femur longest bone in the bodyFlexion: iliopsoas

    Extension: gluteus maximus

    Abduction: gluteus mediusAdduction: adductors

    k

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    knee

    Patella largest sesamoid bone in the bodyMedial meniscus usually damaged compared

    to lateral meniscus because it is more fixed

    Unhappy triad:

    Tear involving the ant. Cruciate ligament, medialcollateral ligament, medial meniscus

    Flexion: hamstring muscles

    Extension: quadriceps femoris

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    Ankle and footFoot 26 bones

    Ant. Talofibular ligament most commonly

    injured in ankle sprainsDorsiflexion: tibialis anterior and extensors of

    digits

    Plantarflexion: triceps surae

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    Man go abroad to wonder at the height of themountain, the huge waves of the sea, the long

    course of rivers, the vast compass of the ocean,the circular motion of the starsbut they passby themselves and dont even notice.

    -Augustine-