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PathologicalSocietyUnderstanding Disease
Nottingham Pathology 2016
Hosted byAcademic Unit of Molecular Pathology
Division of Cancer and Stem Cells School of Medicine, University of Nottingham
VenueEast Midlands Conference Centre and Orchard Hotel
The University of Nottingham, University Park, NG7 2RJ
Companion SessionsAIDPATH · British Lymphoma Pathology Group
Association of Clinical Electron Microscopists · Renal EQAUK Cardiac Pathology Network · UK NEQAS ICC & ISH
9th Joint Meeting of the British Division of the International Academy of Pathology
and the Pathological Society of Great Britain & Ireland
28 June – 1 July 2016
Cover picture creditsThe publishers wish to thank the following for granting permission to use their photographs:Top/Main picture ........................ Photographer: Gerry MolumbyLower two pictures .................... Experience Nottinghamshire
Nottingham Pathology 2016
Important Deadlines
Abstract SubmissionWednesday 9 March 2016 (midnight)
Early Bird RegistrationMonday 23 May 2016 (midnight)
Advance Registration Deadline Monday 13 June 2016 (midnight)
08.00Registration and Coffee
08.55–11.50Symposium: Gynaecological Pathology
09.00–09.30Dr R Graham, Manchester Early Detection Biomarkers for Ovarian Cancer
09.30–10.00Dr S Nicum, Oxford Angiogenesis in Ovarian Cancer
10.00–10.30Prof CS Herrington, EdinburghMolecular Stratification of Vulval Cancer and its Precursors
10.30–10.50Refreshment Break and Trade Exhibition
10.50–11.20Dr J Doorbar, CambridgeCervical Neoplasia: Mechanisms of Disease Progression, Biomarkers and Therapeutic Targets
11.20–11.50Prof MJ Arends, Edinburgh Molecular Pathology of Endometrial Cancer
08.55–11.55Symposium: Pulmonary Pathology
09.00–09.15Prof A Nicholson, London Introduction: Pulmonary Pathology in 2016
09.15–09.45Dr JPC LeQuesne, LeicesterTargeting the Genetic Pathology of Lung Cancer: Where We Are and Where We Are Going
09.45–10.15Prof K Kerr, Aberdeen Immune Checkpoint Modulation in Non-Small Cell Lung Cancer: A Paradigm Shift?
10.15–10.35Refreshment Break and Trade Exhibition
10.35–11.05Prof JR Gosney, Liverpool Diagnostic Pathology of Lung Cancer in 2016: Managing the Challenge and Getting the Answers
11.05–11.35Dr P Cane, LondonQuality and Consistency in the Diagnostic Pathology of Lung Cancer: The LungPath Audit
11.35–11.55Prof A Nicholson, London Panel Discussion and Concluding Comments
12.00–13.00Kristin Henry LectureProf AG Nicholson, LondonEvolution of Classifications in Lung Pathology
13.00–14.00Lunch, Poster Viewing and Trade Exhibition
08.55–11.50Trainees’ Symposium: The Pathologist in the MDT
08.55–11.50Prof AM Hanby, Leeds Prof D Dodwell, Leeds Mr K Horgan, Leeds Dr N Sharma, Leeds A Mock Breast MDT Meeting, illustrating important pathology ‘do’s’ and ‘don’ts’ and the pivotal contribution that pathology makes to the MDT.
09.00–12.00 (17.00)Undergraduate Day
09.00–09.15Dr RJ Byers, ManchesterMr C Slater, ManchesterIntroduction
09.15–09.45Prof P Quirke, Leeds, President, Pathological Society of GB & IrelandPathSoc: Reaching Out to Undergraduates
09.45–10.00Undergraduate Sub-Committee How PathSoc Support Student Societies
10.00–10.30Dr S Lishman, London, President, Royal College of PathologistsUndergraduates and National Pathology Week
10.30–10.50Refreshment Break and Trade Exhibition
10.50–11.10Dr N West, LeedsA Research Career in Pathology
11.10–11.30Dr A McGregor, LeicesterTraining in Histopathology
11.30–12.00Prof AJ Freemont, ManchesterMolecular Pathology: From Bench to Blood Test
09.00–11.50 (17.00)AIDPATH Digital Pathology
Visit www.path.org.ukfor programme details
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PRogRAmmE oVERVIEw Tuesday 28 June 2016PRogRAmmE oVERVIEw Tuesday 28 June 2016
14.00–17.00Symposium: Journal of Pathology – Models of Human Disease
14.00–14.30Dr O Sansom, Glasgow Mouse Models of Intestinal Cancer
14.30–15.00Dr S Charnock-Jones, Cambridge Models of Endometriosis and Ovarian Clear Cell Carcinoma
15.00–15.30Dr CB Whitelaw, EdinburghLarge Animal Models of Human Disease
15.30–15.55Refreshment Break and Trade Exhibition
15.55–16.25Dr J Doorbar, CambridgeModels of Human Papillomavirus- Associated Disease
16.25–16.55Dr D Adams, Cambridge Cross-Species Models of Human Melanoma
14.00–17.00Symposium: Hepatobiliary Pathology
14.00–14.30Prof G Aithal, Nottingham Genetic Factors and Mechanisms underlying Drug Induced Liver Injury
14.30–15.00Prof SG Hubscher, Birmingham Patterns of Drug-Induced Liver Injury
15.00–15.30Dr S Davies, CambridgeLiver Disease in the Immunocompromised Patient
15.30–15.55Refreshment Break and Trade Exhibition
15.55–16.25Prof F Campbell, LiverpoolChallenges in Pancreas Pathology
16.25–16.55Dr AM Zaitoun, Nottingham The Role of the Pathologist in the Diagnosis, Management and Prognosis of Pancreatobiliary Neoplasms
14.00–17.00Symposium: Head and Neck Pathology
14.00–14.40Dr MC Robinson, Newcastle upon Tyne PREDICTR Study: Biomarkers in Oropharyngeal Squamous Cell Carcinoma
14.40–15.20Prof CJLM Meijer, Amsterdam, The Netherlands Is it Worth Vaccinating Boys Against HPV – A Pathologist’s Perspective
15.20–15.45Refreshment Break and Trade Exhibition
15.45–16.20Dr A Sandison, LondonThe New WHO Classification of Head and Neck Tumours: Principle Changes and New Entities
16.20–16.55Dr S Thomas, BristolHead and Neck 5000 Study – Now Being Analysed
17.00–17.50Public LectureTitle and Speaker to be announced
18.30–20.30welcome Reception and (Optional) Cave TourNottingham CastleBuses at 18.00
14.00–17.00oral Presentations
14.00–16.50Undergraduate Day
14.00–14.05Dr R Byers, Manchester Introduction to the Session
14.05–14.20Platform 1
14.20–14.35Platform 2
14.35–14.50Platform 3
14.50–15.05Platform 4
15.05–15.20Platform 5
15.20–15.45Refreshment Break and Trade Exhibition
15.45–15.50Presentation: Undergraduate Essay Prize Winner 2016
15.50–16.05Platform 6
16.05–16.20Platform 7
16.20–16.35Platform 8
16.35–16.50Platform 9
14.00–17.00AIDPATH Digital Pathology
Visit www.path.org.ukfor programme details
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PRogRAmmE oVERVIEw Tuesday 28 June 2016PRogRAmmE oVERVIEw Tuesday 28 June 2016
08.00Registration and Coffee
08.55–11.50Symposium: Gastrointestinal Pathology
09.00–09.30Prof A Sottoriva, London Somatic Evolution of Colorectal Cancer
09.30–10.00Prof L Vermeulen, Amsterdam, The Netherlands Stratified Medicine in Colorectal Cancer
10.00–10.30Dr SA McDonald, LondonSomatic Evolution of Barrett’s / Oesophageal Cancer
10.30–10.50Refreshment Break and Trade Exhibition
10.50–11.20Prof HI Grabsch, Maastricht, The NetherlandsMolecular Heterogeneity of Gastric Cancer
11.20–11.50Prof T Yao, Kyoto, Japan Guest Lecture, Japanese Society of Pathology: Gastric Adenocarcinoma of Fundic Gland Type. A New Entity
08.55–11.50Symposium: Breast Pathology
09.00–09.30Dr A Lee, Nottingham The Role of Immunohistochemistry in Diagnosis in Breast Pathology
09.30–10.00Prof SE Pinder, London An Update on the Biology, Pathology and Implictions of Breast Cancer Risk Lesions
10.00–10.30Dr E Rakha, NottinghamAn Update on the Molecular Classification of Breast Cancer
10.30–10.50Refreshment Break and Trade Exhibition
10.50–11.20Prof LJ Jones, LondonThe Role of Myoepithelial Cells in Breast Disease
11.20–11.50Prof JS Reis-Filho, New York, USAContribution of Molecular Techniques to Understanding the Biology of Uncommon Breast Lesions
12.00–12.45CL oakley LectureDr TA Graham, LondonQuantifying Clonal Evolution in the Human Colon
13.00–14.00Lunch, Poster Viewing and Trade Exhibition
08.00–08.55Trainees’ meet The Experts: Dermatopathology
08.00–08.25Dr W Merchant, Leeds
08.25–08.50Dr AM Robson, London
08.55–12.00Symposium: Genitourinary Pathology
09.00–09.30Dr M Varma, Cardiff Atypical Large Glandular Proliferations of the Prostate
09.30–10.00Prof DM Berney, London An Introduction to the New Grading System for Prostate Cancer
10.00–10.30Dr T Walton, NottinghamWhat the Clinician Wants in Prostatic Biopsy and Prostatectomy Reporting
10.30–10.50Refreshment Break and Trade Exhibition
10.50–11.20Dr H Ahmed, LondonPathology and Imaging in Prostate Cancer
11.20–11.50Prof C Magi-Galuzzi, Cleveland, USA Prostate Cancer: Molecular and Immunochemical Approaches
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PRogRAmmE oVERVIEw wednesday 29 June 2016PRogRAmmE oVERVIEw wednesday 29 June 2016
14.00–17.00oral Presentations — 1
15.15–15.45Refreshment Break and Trade Exhibition
14.00–17.00oral Presentations — 2
15.15–15.45Refreshment Break and Trade Exhibition
17.00–18.30Poster Viewing and Chairman’s Rounds
14.00–17.00oral Presentations — 3
15.15–15.45Refreshment Break and Trade Exhibition
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PRogRAmmE oVERVIEw wednesday 29 June 2016PRogRAmmE oVERVIEw wednesday 29 June 2016
08.00Registration and Coffee
08.55–12.00Symposium: Mechanisms of Disease – Cutting Edge Topics
09.00–09.30Prof J Shaw, Leicester Circulating Tumour DNA
09.30–10.00Prof L Durrant, Nottingham Cancer Immunotherapy
10.00–10.30Prof D Bates, NottinghamPros and Cons in Pathological Angiogenesis – Why Stopping Blood Vessels Growing is Harder in Some Pathologies than Others
10.30–11.00Refreshment Break and Trade Exhibition
11.00–11.30Prof W Irving, NottinghamViral Oncogenesis and Hepatocellular Carcinoma
11.30–12.00Dr M Srinivasan, Nottingham Targeting DNA Repair for Personalisation of Breast Cancer Therapy
08.55–12.00Symposium: Musculoskeletal Pathology
09.00–09.30Dr P Taniere, BirminghamGIST, An Expanding Molecular Landscape Driving a Diagnostic Service – What’s New and Relevant
09.30–10.00Dr N Pillay, London Is There a Role for Genetics in the Diagnosis of Undifferentiated Sarcomas?
10.00–10.30Dr MF Amary, London Molecular Pathology of Bone Tumours – Getting More Accurate Diagnostic, Prognostic and Predictive Information
10.30–11.00Refreshment Break and Trade Exhibition
11.00–11.30Dr A Grigoriadis, LondonStem Cells and Lineage Commitment in Bone Tumours
11.30–12.00Dr F Puls, Gothenburg, SwedenThe Expanding Family of Ewing’s and Related Tumours
08.25–12.30Symposium: Renal Pathology
08.30–08.42Dr C Roufosse, London I Learned Something New About That Case
08.42–08.54Dr NS Brearley, Portsmouth I Learned Something New About That Case
08.54–09.06Dr K Wood, Newcastle upon TyneI Learned Something New About That Case
09.06–09.18Dr R Perera, LondonI Learned Something New About That Case
09.18–09.30Prof ISD Roberts, OxfordI Learned Something New About That Case
09.30–10.00Prof HT Cook, LondonAutosonal Dominant Tubulointerstitial Kidney Disease
10.00–10.30Dr C Roufosse, London Banff 2015 Report
10.30–10.50Refreshment Break and Trade Exhibition
10.50–11.10Dr M Sheaff, London RC Path / Renal Registry Issues
11.10–12.00Prof ISD Roberts, Oxford Renal EQA
12.00–12.30Dr D Neil, Birmingham Renal Transplant EQA
08.00–09.00Trainees’ meet The Experts: GI-Sessile Serrated Lesions
08.00–08.30Prof GT Williams, Cardiff
08.30–09.00Dr AC Bateman, Southampton
08.00Registration and Coffee
09.00–12.00 (17.00)UK NEQAS ICC and ISH
Visit www.path.org.ukfor programme details
09.00–12.00 (17.00)BLPg (British Lymphoma Pathology Group)
Visit www.path.org.ukfor programme details
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PRogRAmmE oVERVIEw Thursday 30 June 2016PRogRAmmE oVERVIEw Thursday 30 June 2016
13.30–16.00ACEm(Association of Clinical Microscopists)
Visit www.path.org.ukfor programme details
12.00–17.00UK NEQAS ICC and ISH
Visit www.path.org.ukfor programme details
12.00–17.00BLPg (British Lymphoma Pathology Group)
Visit www.path.org.ukfor programme details
12.00–13.30Lunch, Poster Viewing and Trade Exhibition
12.00–13.00Pathological Society Annual general meeting
14.00–17.00Plenary oral Presentations
15.30–16.00Refreshment Break and Trade Exhibition
17.15–18.00Doniach LectureProf IO Ellis, NottinghamLooking at Breast Cancer
19.30–23.00Conference Dinnerwith dodgems and musical entertainment provided by Mood Indigo
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PRogRAmmE oVERVIEw Thursday 30 June 2016PRogRAmmE oVERVIEw Thursday 30 June 2016
08.30–10.00Trainee: Slide Seminar Discussion
08.30–08.40Dr K Moutasim, Southampton Case 1
08.40–08.50Dr K Allen, Leeds Case 2
08.50–09.00Dr M Clarke, Brighton Case 3
09.00–09.10Dr O Dotsenko, Sheffield Case 4
09.10–09.20Dr G Petts, Manchester Case 5
09.20–09.30Dr J Sampson, Newcastle upon Tyne Case 6
09.30–09.40Case Competition Winner: Trainee
09.40–09.50Case Competition Winner: Undergraduate
09.00–12.30 (14.45)BLPg (British Lymphoma Pathology Group)
Visit www.path.org.ukfor programme details
09.00–12.30 (17.00)UK Cardiac Pathology Network
Visit www.path.org.ukfor programme details
08.00Registration and Coffee
09.55–12.30Symposium (in association with The Royal College of Pathologists): Molecular Pathology – Transformative Technologies
10.00–10.30Dr M Jiminez-Linan, Cambridge The Pathologist and the 100K Genome Project
10.30–11.00Dr A Sharif, Nottingham Principles of Next Generation Sequencing
11.00–11.30Refreshment Break
11.30–12.00Dr X Fernandez, Thermo-Fisher ScientificNext Generation Sequencing (2): Applications
12.00–12.30Dr S Picton, Pacific BiosciencesSMRT® Technology – A Paradigm Shift in Sequencing
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PRogRAmmE oVERVIEw Friday 1 July 2016PRogRAmmE oVERVIEw Friday 1 July 2016
12.30–13.30Lunch
13.30–16.30Symposium (in association with The Royal College of Pathologists): Molecular Pathology – Transformative Technologies (continued)
13.30–14.00Prof Z Takats, London Imaging Mass Spectometry
14.00–14.30Dr B Gangadharan, Oxford The Use of Proteomics in Diagnostics: Liver Fibrosis Biomarkers
14.30–15.00Prof PS Monks, Leicester Breathomics – The New Molecular Pathology?
15.00–15.30Refreshment Break
15.30–16.00Prof H Sewell, Nottingham Early Cancer Detection Using Tumour Specific Autoantibodies: the signal has been there all along
16.00–16.30Dr D-H Kim, Nottingham Metabolomics: Shedding Light on Human Health and Diseases
17.00End of Conference
12.30–14.45BLPg (British Lymphoma Pathology Group)
Visit www.path.org.ukfor programme details
12.30–17.00UK Cardiac Pathology Network
Visit www.path.org.ukfor programme details
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PRogRAmmE oVERVIEw Friday 1 July 2016PRogRAmmE oVERVIEw Friday 1 July 2016
RegistRationRegistration is online only via: www.path.org.uk
advance RegistRation Advance registration will close on monday 13 June 2016 (midnight).Thereafter delegates may only register on-site on arrival at the meeting.
cancellationsA cancellation fee of £20 will be deducted from any refund due for cancellations received in writing by Wednesday 8 June 2016. No refunds will be made after Wednesday 8 June 2016.
RefReshmentsAll refreshments, including lunch, are included in the daily registration fee.
delegate enRolment (AT THE MEETING)Enrolment at the Delegate Reception Desk will take place from 08.00 hrs each day unless stated otherwise.
X concessionsDelegates from categories: Non-Member Undergraduate Student and Non-Member Concessionary must provide an identification document as proof of their student or trainee status, including NTNs where applicable. Proof must be by way of a statement from the Head of Department. Please email to: [email protected] (see registration website for template wording).
special offeR: NoN-MeMber UK UNdergradUate StUdeNtSJoin the Royal College of Pathologists and get free membership of the Pathological Society to benefit from free meeting registration for Nottingham Pathology 2016 and all future Pathological Society scientific meetings.
For more information use the URLs below:https://www.rcpath.org/discover-pathology/are-you-an-undergraduate-.htmlhttp://www.pathsoc.org/index.php/about/undergraduates
EARLY BIRD REgISTRATIoN FEESUNTIL mIDNIgHT oN moNDAY 23 mAY 2016
Delegate Type Fee Categories Per Day or Part Day
Conference Dinner
BDIAP or Pathological Society Member
Ordinary Member, Consultant and/or equivalent position £ 115 £ 60
BDIAP or Pathological Society Concessionary Member
Biomedical Scientist; Honorary or Senior Member; PhD Student; Post-Doctoral Fellow, Technician and Trainee
£ 38 £ 60
Pathological Society Undergraduate Student Member
Undergraduate Student Free £ 30
Non-MemberConsultant and/or equivalent position £ 165 £ 60
Non-Member Concessionary XBiomedical Scientist; PhD Student; Post-Doctoral Fellow, Technician and Trainee
£ 53 £ 60
Non-Member Undergraduate Student XSee special offer below
Undergraduate Student £ 53 £ 60
LATE REgISTRATIoN FEESFRom mIDNIgHT oN TUESDAY 24 mAY 2016
Delegate Type Fee Categories Per Day or Part Day
Conference Dinner
BDIAP or Pathological Society Member
Ordinary Member, Consultant and/or equivalent position £ 170 £ 80
BDIAP or Pathological Society Concessionary Member
Biomedical Scientist; Honorary or Senior Member; PhD Student; Post-Doctoral Fellow, Technician and Trainee
£ 60 £ 80
Pathological Society Undergraduate Student Member
Undergraduate Student Free £ 30
Non-MemberConsultant and/or equivalent position £ 250 £ 80
Non-Member Concessionary XBiomedical Scientist; PhD Student; Post-Doctoral Fellow, Technician and Trainee
£ 80 £ 80
Non-Member Undergraduate Student XSee special offer
Undergraduate Student £ 80 £ 80
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FEES AND REgISTRATIoN FEES AND REgISTRATIoN
slide seminaR competition and Review sessionviewingDigital slide images of all cases will be available for preview on from 09.00 on Tuesday 28 June and will be available on the website in advance of the meeting.
discussion sessionFriday 1 July.
pRizeThe prize is a case of champagne. The winner will be announced at the Conference Dinner on Thursday 30 June. At the discretion of the winner, by tradition, this is shared amongst those present at the dinner!
submission of abstRacts – deadlinewednesday 9 march 2016 (midnight)Abstracts must be submitted online via: www.path.org.uk
Unless otherwise instructed by the authors, all abstracts will be published in the Journal of Pathology On-line Supplement at the discretion of the Meetings Secretaries and the Editor.Presenters must register for the meeting in advance.
tRade exhibitionThere will be a Trade Exhibition at the meeting adjacent to the poster and catering areas.
tRavelling to nottinghamFor travel information please visit this link:
accommodationAccommodation has been reserved for delegates, please visit: www.path.org.uk
inteRnet accessWi-Fi internet access will be available for delegates at the meeting.
venue locationEast Midlands Conference Centre, University of Nottingham, Nottingham Park, Nottingham NG7 2RJ.
fRee papeR sessionsoRal communicationsPresentations will be allocated 15 minutes each, to include discussion. These will be selected on the basis of the written abstracts. those papers not selected for oral presentation will be required to be presented as posters.
plenaRy oRal sessionThere will be a Plenary Oral Session in which the highest ranking submitted oral abstracts will be presented.
prizeA prize for the best Plenary Oral Presentation will be awarded by the Journal of Pathology at the Conference Dinner.
poster viewing and poster RoundsOfficial Poster Chairman will review the posters as shown in the Programme Summary. A drinks reception will also be held. It is requested that posters remain on display until Thursday 30 June.
posteR pRizesbdiap posteR pRizesAwarded for the best 3 posters relevant to diagnostic pathology.
pathological society posteR pRizesPathological Society’s Sir Alastair Currie Prize and second and third poster prizes
winneRsWinners will be announced at the Conference Dinner on 30 June.
posteR pResentationsPublication of abstracts in the Journal of Pathology On-Line SupplementThe presenting author (or another author) must attend the meeting to present the poster during their allocated poster round in order for the abstract to be published in the Journal of Pathology On-line Supplement.
Travel information
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ADDITIoNAL INFoRmATIoN ADDITIoNAL INFoRmATIoN
continuing pRofessional development (cpd)Royal college of pathologistsThis Meeting has been approved by the Royal College of Pathologists for the purpose of Continuing Professional Development. The following credits will be awarded: Full Day*Tuesday 28 June 6 creditsWednesday 29 June 6 creditsThursday 30 June 6 creditsFriday 1 July 4 credits* The Society is not permitted to issue certificates for less than full day attendance. Delegates should use their reflective notes section of their CPD Portfolio to self-accredit if attending less than full days.
institute of biomedical science (ibms)Applications for accreditation have been submitted and this page will be updated when approval has been received.
notice to membeRsPlease ensure that all relevant information regarding this Meeting is passed on to any non-members who wish to participate.
disclaimeRThe British Division of the IAP and Pathological Society of Great Britain & Ireland cannot be held responsible for any injury or loss sustained during the Meeting.
fuRtheR infoRmationAny further information or amendments tothis programme will be posted on the meeting webite: www.path.org.uk
Please note all timings, titles and speakers are subject to alteration.
social activitiestuesday 28 JuneWelcome Reception. Nottingham Castle (free of charge – reserve your ticket when registering online) with optional Cave Tours (£5 per ticket).
For information on Nottingham Castle visit this link:
thuRsday 30 JuneConference Dinner, Banqueting Suite, East Midlands Conference Centre.Includes dodgems and musical entertainment provided by Mood Indigo. For more information see their website: www.mood-indigo.co.uk
Tickets are £60 (price increases after 23 may). £30 for undergraduates. Please reserve your ticket when registering online.
local places of inteRestFor information please visit: www.experiencenottinghamshire.com
enquiRiesmeeting websitewww.path.org.uk
british division of the international academy of pathologyAddress PO Box 73, Westbury-on-Trym, Bristol BS9 1RYTelephone +44 (0)117 907 7940Fax +44 (0)117 907 7941E-mail [email protected]
pathological society of great britain & irelandAddress 150 Minories, London EC3N 1LSTelephone +44 (0)20 7347 5751 / 5752E-mail [email protected]
Nottingham Castle
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ADDITIoNAL INFoRmATIoN ADDITIoNAL INFoRmATIoN