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N.C. Weekly Influenza Summary - April 13, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY 2018-2019 INFLUENZA SEASON WEEK ENDING APRIL 13, 2019 ILINet has now expanded to include emergency department data that were previously reported separately. *For more information about national data visit https://www.cdc.gov/flu/weekly/index.htm. (Influenza-Like Illness in ILINET) Influenza Surveillance, NC 2016-2019 0% 1% 2% 3% 4% 5% 6% 7% 8% 9% 10% 11% % ILI 10/06 10/20 11/03 11/17 12/01 12/15 12/29 01/12 01/26 02/09 02/23 03/09 03/23 04/06 04/20 05/04 05/18 Week Ending Date 2018-2019 2017-2018 2016-2017 Statewide Updates Influenza-like illness (ILI) slightly decreased for week ending April 13, 2019. The geographic spread of flu was LOCAL for week ending 4/13/2019. Of the four samples submitted to the State Laboratory of Public Health (SLPH) for viral testing this week (ending 4/13/2019) none were positive for influenza virus. Hospital-based Public Health Epidemiologists (PHEs) reported 152 positive influenza virus results out of 1517 samples tested during week 15 (ending 4/13/2019); 96 were positive for influenza A(unknown), 28 were positive for influenza A(H3), 16 were positive for influenza A(H1), and 12 were positive for influenza B virus. Regional Updates The proportion of visits due to ILI in Region 4 (Southeastern US) was at 2.23% for week 14 (ending 4/6/2019). The baseline for the region is 2.2%. National Updates The proportion of outpatient visits due to ILI nationally was at 2.76% for week 14 (ending 4/6/2019). The national baseline for ILI is 2.2%. International Updates Worldwide seasonal influenza subtype A viruses accounted for a majority of detections. For more country specific details please visit: http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/ For more flu information visit https://flu.nc.gov and https://www.cdc.gov/flu.

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Page 1: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 1

NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY2018-2019 INFLUENZA SEASONWEEK ENDING APRIL 13, 2019

ILINet has now expanded to include emergency department data that were previously reported separately.

*For more information about national data visit https://www.cdc.gov/flu/weekly/index.htm.

(Influenza-Like Illness in ILINET)

Influenza Surveillance, NC 2016-2019

0%

1%

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% I

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Week Ending Date

2018-20192017-20182016-2017

StatewideUpdates

Influenza-like illness (ILI) slightly decreased for week ending April 13, 2019.

The geographic spread of flu was LOCAL for week ending 4/13/2019.

Of the four samples submitted to the State Laboratory of Public Health (SLPH) for viral testing this week(ending 4/13/2019) none were positive for influenza virus.

Hospital-based Public Health Epidemiologists (PHEs) reported 152 positive influenza virus results out of1517 samples tested during week 15 (ending 4/13/2019); 96 were positive for influenza A(unknown), 28were positive for influenza A(H3), 16 were positive for influenza A(H1), and 12 were positive for influenza Bvirus.

RegionalUpdates

The proportion of visits due to ILI in Region 4 (Southeastern US) was at 2.23% for week 14 (ending4/6/2019). The baseline for the region is 2.2%.

NationalUpdates

The proportion of outpatient visits due to ILI nationally was at 2.76% for week 14 (ending 4/6/2019). Thenational baseline for ILI is 2.2%.

InternationalUpdates

Worldwide seasonal influenza subtype A viruses accounted for a majority of detections. For more countryspecific details please visit:http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/

For more flu information visit https://flu.nc.gov and https://www.cdc.gov/flu.

Page 2: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 2

INFLUENZA-LIKE ILLNESSES

By Reporting Sites, 2018-2019

Week # - Ending (Sentinels Reporting) # ILI # Patients % ILI

#40 - 10/06/2018 157 974 108,547 0.90

#41 - 10/13/2018 160 1139 108,746 1.05

#42 - 10/20/2018 161 1261 109,669 1.15

#43 - 10/27/2018 161 1425 104,003 1.37

#44 - 11/03/2018 162 1548 106,418 1.45

#45 - 11/10/2018 161 1428 94,176 1.52

#46 - 11/17/2018 162 1389 82,670 1.68

#47 - 11/24/2018 159 1263 75,983 1.66

#48 - 12/01/2018 159 1843 102,756 1.79

#49 - 12/08/2018 158 1793 101,347 1.77

#50 - 12/15/2018 155 1779 90,867 1.96

#51 - 12/22/2018 152 1928 96,749 1.99

#52 - 12/29/2018 155 2573 92,349 2.79

#1 - 01/05/2019 157 2776 102,884 2.70

#2 - 01/12/2019 154 2366 102,084 2.32

#3 - 01/19/2019 158 2620 102,440 2.56

#4 - 01/26/2019 157 3601 102,915 3.50

#5 - 02/02/2019 155 4914 107,517 4.57

#6 - 02/09/2019 156 7608 121,081 6.28

#7 - 02/16/2019 158 7143 113,442 6.30

#8 - 02/23/2019 156 6405 109,587 5.84

#9 - 03/02/2019 156 4963 106,467 4.66

#10 - 03/09/2019 156 3876 101,799 3.81

#11 - 03/16/2019 154 3694 108,147 3.42

#12 - 03/23/2019 156 2994 109,642 2.73

#13 - 03/30/2019 153 2675 110,024 2.43

#14 - 04/06/2019 151 2118 106,396 1.99

#15 - 04/13/2019 147 1784 108,577 1.64

Page 3: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 3

PHE RESPIRATORY VIRAL PATHOGEN SURVEILLANCE

Positive test results for selected respiratory viruses are reported on a weekly basis by Public Health Epidemiologists(PHEs) located in seven of the largest hospital networks across North Carolina. The graph below shows the number ofpositive tests for respiratory syncytial virus (RSV), parainfluenza, adenovirus, rhinovirus, and human metapneumovirus(hMPV) by week.

These data provide a useful indication of which other respiratory viruses are circulating and possibly contributing to ILI inthe state. Please note that the total number of tests performed is not available from all hospital networks, so the overallproportion testing positive cannot be calculated. Also, testing protocols and practices differ among hospitals. Finally,these numbers reflect test results from participating hospitals only and might not be reflective of the entire state.

*Most facilities use tests that do not distinguish rhinoviruses from enteroviruses.

(Data source: NC DETECT)

PHE Surveillance: Positive Respiratory Virus Test Results by Week

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InfluenzahMPVRhinovirus*AdenovirusParainfluenzaRSV

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• Influenza was the most frequently identified respiratory viral pathogen during week 15 (ending 04/13/2019) followed by Rhinovirus*.

Influenza Virus Isolates Identified by PHE Facilities for 2018–2019 Season*Influenza Virus Isolates Identified by PHE Facilities for 2018–2019 Season*

Virus Type# New positive results

(04/07/2019- 04/13/2019)# Cumulative positive results

(09/30/2018-05/18/2019)

A(H1) 16 785

A/H3 28 1037

A (subtype unknown) 96 7077

B 12 155

Total 152 9054

*2018-2019 influenza season began September 30, 2018.NOTE: This table includes isolates tested as of 09/30/2018.

Page 4: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 4

PHE ACUTE RESPIRATORY ADMISSIONS SURVEILLANCE

The number of patients admitted to the hospital with fever plus respiratory symptoms in the absence of a known causeother than influenza is reported on a weekly basis by Public Health Epidemiologists (PHEs) located in seven of the largesthospital networks across North Carolina. The graph below shows the number of acute respiratory illness admissions toparticipating hospitals by age group.

In conjunction with other surveillance information, these data help us monitor for changes in severity of respiratoryillness during periods when influenza is circulating. Please note that these reports are not limited to patients withlaboratory-confirmed influenza infection. Also, these numbers reflect admissions to participating hospitals only and arenot be reflective of the entire state.

Data source: NC DETECT

PHE Surveillance: Hospital Admissions for Acute Respiratory Illness by Week

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Week Ending Date

TotalAge UnknownAge 65+Age 25 - 64Age 5 - 24Age 0 - 4

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• Acute respiratory admissions decreased during week 15 (ending 04/13/2019).

• The highest number of acute respiratory admissions during week 15 was for patients Age 25 - 64 followed by Age 65+.

Page 5: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 5

Influenza Positive Tests Reported by the NC State Laboratory of Public Health (SLPH)

† Percent of submitted specimens for any influenza.

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B (not subtyped)B (Yamagata)B (Victoria)Seasonal A (H3)2009 A (H1N1)A (not subtyped)

Percent Positive †

Influenza Virus Isolates From In-State Patients Identified by the State Laboratory Of Public Health 2018–2019 Season*Influenza Virus Isolates From In-State Patients Identified by the State Laboratory Of Public Health 2018–2019 Season*

Virus Type # New Positive Results # Cumulative Positive Results

A (unknown) 0 10

2009 A(H1N1) 0 87

A(H3) 0 76

B (unknown) 0 0

B (Victoria) 0 1

B (Yamagata) 0 1

Total 0 175

*2018-2019 influenza season began September 30, 2018.NOTE: This table includes isolates tested as of 09/30/2018. This table does not include influenza isolates

identified by other laboratories.

Influenza Positive Tests Reported by the NC State Laboratory of Public Health (SLPH) and PHE Facilities

† Percent of submitted specimens for any influenza.

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Seasonal BSeasonal A (H3)A (H1)A (not subtyped)

Percent Positive †

Page 6: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 6

FLU SURVEILLANCE BY REGIONS

*This graph begins with data starting week ending October 6, 2018 for the 2018-2019 influenza season.

NC DETECT ED Influenza-Like Illness (ILI), 2018-2019

Percentage of Total Visits by Week

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Week Ending Date

Region 7Region 6Region 5Region 4Region 3Region 2Region 1

Flu Surveillance Regions

Region 1 Region 2 Region 3 Region 4Region 5 Region 6 Region 7

ALAMANCE

ALEXANDER

ALLEGHANY

ANSON

ASHE

AVERY

BEAUFORT

BERTIE

BLADEN

BRUNSWICK

BUNCOMBE

BURKE

CABARRUS

CALDWELL

CAMDEN

CARTERET

CASWELL

CATAWBA CHATHAM

CHEROKEE

CHOWAN

CLAY

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COLUMBUS

CRAVEN

CUMBERLAND

CURRITUCK

DAREDAVIDSON

DAVIE

DUPLIN

DURHAM

EDGECOMBE

FORSYTH

FRANKLIN

GASTON

GATES

GRAHAM

GRANVILLE

GREENE

GUILFORD

HALIFAX

HARNETT

HAYWOOD

HENDERSON

HERTFORD

HOKE

HYDE

IREDELL

JACKSON

JOHNSTON

JONES

LEE

LENOIR

LINCOLN

MC DOWELL

MACON

MADISON MARTIN

MECKLENBURG

MITCHELL

MONTGOMERYMOORE

NASH

NEW HANOVER

NORTHAMPTON

ONSLOW

ORANGE

PAMLICO

PASQUOTANK

PENDER

PERQUIMANS

PERSON

PITT

POLK

RANDOLPH

RICHMOND

ROBESON

ROCKINGHAM

ROWAN

RUTHERFORD

SAMPSON

SCOTLAND

STANLY

STOKESSURRY

SWAIN

TRANSYLVANIA

TYRRELL

UNION

VANCE

WAKE

WARREN

WASHINGTON

WATAUGA

WAYNE

WILKES

WILSON

YADKIN

YANCEY

3

45

6

1

7

2

Page 7: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 7

NC INFLUENZA-ASSOCIATED DEATHS

An influenza-associated death is defined for surveillance purposes as a death (adult or pediatric) resulting from aclinically compatible illness that was confirmed to be influenza by an appropriate laboratory or rapid diagnostic test withno period of complete recovery between the illness and death.

NC Influenza-Associated Deaths*

Influenza-Associated DeathsThis Week (04/07/2019 – 04/13/2019)

Total Influenza-Associated DeathsThis Season (starting 09/30/2018)

4 192

*These numbers are based on reports submitted by providers to the NC Division of Public Health. Data arepreliminary and subject to change as updated information becomes available. Deaths that occurred on or after

09/30/2018 will be reflected in this report for the 2018-2019 season.

Reported in North Carolina by Age Group*

Laboratory Confirmed Influenza-Associated Deaths

08

1624324048566472808896

104112120

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0-4 5-17 18-24 25-49 50-64 65+

Age Group (Years)

Reported in North Carolina by Week of Death*

Laboratory Confirmed Influenza-Associated Deaths

0 0 01 1

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PediatricAdult

Page 8: NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE … · N.C. Weekly Influenza Summary - April 6, 2019 1 NORTH CAROLINA WEEKLY INFLUENZA SURVEILLANCE SUMMARY WEEK ENDING APRIL 6, 2019

N.C. Weekly Influenza Summary - April 13, 2019 8

ILI Network Provider Locations, NC 2018-2019

Non-Hospital Participants In North Carolina’s Influenza Sentinel Surveillance Program Report Data To CDC

LOCAL HEALTH DEPARTMENT/DISTRICT OFFICES - 21

Alamance County Health Department

Cabarrus Health Alliance

Caldwell County Health Department

Craven County Health Department

Duplin County Health Department

Franklin County Health Department

Henderson County Health Department

Johnston County Health Department

Lee Primary Care

Montgomery County Health Department

Northampton County Health Department

Pender County Health Department

Pitt County Public Health Center

Richmond County Health Department

Rockingham County Health Department

Stanly County Health Department

Stokes Family Health Center

Surry County Health and Nutrition Center

Union County Health Department

Wake County Health Department, Children’s Clinic

Wilkes County Health Department

PRIVATE PRACTITIONERS - 24

Bakersville Community Medical Center

Blue Cross and Blue Shield of N.C.

Blue Ridge Community Health Services

Butner-Creedmoor Family Medicine

Catawba Family Care

Coastal Childrens Clinic

Colerain Primary Care

Creswell Primary Care

Dilworth Pediatrics

ECU Brody School of Medicine – Department ofPediatrics

Family Care Center

Haywood Pediatric and Adolescent Medicine Group, PA

Hot Springs Health Program

MEDAC Health Services at Shipyard Blvd.

MEDAC Health Services at Porter’s Neck

MEDAC Health Services at Military Cutoff

Minute Clinic - Cary

Murfreesboro Primary Care

Oxford Family Physicians

PrimeCare

PrimeCare of Northpoint

Roanoke Chowan Community Health Center

SAS Institute Health Care Center

Sisters of Mercy Urgent Care, South

COLLEGES AND UNIVERSITIES STUDENT HEALTHPROGRAMS - 15

Appalachian State University Student Health Services

Davidson College Student Health Center

ECU Student Health Services

Elizabeth City State University Student Health Services

Elon University R. N. Ellington Health and CounselingCenter

Fayetteville State University

Meredith College Student Health Center

NC Agricultural &Technical State University StudentHealth Services

NC State University Student Health Services

UNC-Chapel Hill Student Health Services

UNC-Charlotte Student Health Services

UNC-Greensboro Student Health Services

UNC-Pembroke Student Health Services

Wake Forest University Student Health Services

Winston-Salem State University