norovirus - the perfect human pathogen
TRANSCRIPT
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PATHOGENPATHOGEN
The
Perfect Human
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Highly
ContagiousDiarrhea
The Norovirus alters
the intestinal lining,
causing cells to dump
fluid, which gets
washed out of the bodyalong with many, many,
many noroviruses.
http://phenomena.nationalgeographic.com/2013/01/02/the-norovirus-a-study-in-puked-perfection/
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http://jid.oxfordjournals.org/content/205/11/1622.full
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http://www.ncbi.nlm.nih.gov/pubmed/21876931
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Highly
ContagiousVomit
Noroviruses hijack
our nervous system to
slow down the passage
of food from the
stomach into the
intestines.
http://www.mdpi.com/1999-4915/2/3/748
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Easily
SpreadAirborne
Noroviruses easilyfloat through the air
and settle on
surfaces like food,
countertops, sinks ortoilets.
http://jcm.asm.org/content/48/7/2552
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Tougher Than
Bear GryllsFreeze, Cook or Clean
noroviruses survive
both freezing and
heating and resist
many common chemicaldisinfectants.
http://phenomena.nationalgeographic.com/2013/01/02/the-norovirus-a-study-in-puked-perfection/
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http://blogs.scientificamerican.com/artful-amoeba/2012/01/17/misery-in ducing-norovirus-can-survive-for-months-perhaps-years-in-drinking-water/
http://www.sciencedirect.com/science/article/pii/S0168160505005854
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RapidEvolution
Limited Immunity
noroviruses are genetically diverse andevolve rapidly. That means we’ve only
got a few months of immunity, and then
we’re fair game for another brutal bout
of projectile puking and diarrhea.
http://www.ncbi.nlm.nih.gov/pubmed/16343580?dopt=Abstract
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What Doesn’tKill You...
Moderate Virulencenoroviruses are only moderately virulent
allowing a large pool of potential hosts
to survive...and be reinfected.
again.
and again.
and again...
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Recipe for an Outbreak
1cardealership
1Infectedtoddler1babychangingstation
SeveralBillionNoroviruses2bigpacksofdrypapertowels
16employees(12sick)
Ingredients:
http://www.micro-blog.info/2013/07/this-is-what-happens-when-norovirus-sprays-from-a-toddler/
http://www.salahqutaishat.com/1/post/2013/07/the-st-hit-the-fan-at-an-auto-dealer-in-oregon.html
http://www.ncbi.nlm.nih.gov/pubmed/23559462
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Recipe for an Outbreak
Directions:
1. Bringaninfectedtoddlerto
cardealershipandliberallyspraybabychangingstationwithfeces.Leavethemessforadealershipemployeestocleanup.
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Recipe for an Outbreak
Directions:
2. Cleanupthebabychangingstationusingonly
drypapertowels.Leavesomeinfectedfeces(withbillionsofnoroviruses)visibleonthebabychangingstation.Foradditionaloutbreaksleavethefecesvisibleforweeks.
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Recipe for an Outbreak
Directions:
3. Returntothemeeting,touchsurfaces,handlefoodandinfect75%ofyourco-workers
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Treatment
NOTHING!
•
antiviral drugs•vaccine
•time
•plenty of fluids
Dehydration is the mostcommon complication and
in severe cases can
require IV fluids.
http://www.cdc.gov/norovirus/about/treatment.html
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Prevention
The best way to help
prevent norovirus isto practice proper
hand washing and
general cleanliness.
http://www.cdc.gov/norovirus/preventing-infection.html
Wash Your Hands
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Prevention
Remove vomit or diarrhea
right away!
Use soapy water to wash
surfaces that contacted
vomit or diarrhea and allnearby surfaces, such as
door knobs and toilet
handles
http://www.disinfect-for-health.org/wp-content/themes/disinfect/pdfs/NorovirusIncident_8.5x11_Eng_Color.pdf
Clean contaminatedsurfaces
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Prevention
Rinse thoroughly withplain water
Wipe dry with paper towels
http://www.epa.gov/oppad001/list_g_norovirus.pdf
Clean contaminatedsurfaces
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Prevention
Disinfect surfaces by
applying a chlorine bleach
solution or EPA approved
disinfectant
Disinfect Surfaces
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Prevention
Prepare a chlorine bleach
solution (or disinfectant)
Allow disinfectant to airdry for surfaces unlikely
to have food or mouth
contact
Rinse all surfaces
intended for food or mouth
contact with plain water
before use
Disinfect Surfaces
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Cleaning and
Disinfection Resources• Restroom Cleaning Procedures
• EPA Approved Disinfectants
• Baby Changing Station Sanitation
Instructions
• Industry Cleaning Tips
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M C
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More CommonThan theCold?No. But...
Norovirus is the most
common cause of acute
gastroenteritis in
the United States
https://www.osha.gov/Publications/norovirus-factsheet.pdf
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So What’s
the BigDeal?
It’s expensive!
•21 million illnesses
•2 million outpatient visits
•400,000 emergency department visits•70,000 hospitalizations
•800 deaths each year
http://www.cdc.gov/norovirus/php/illness-outbreaks.html
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It’s more
commonthan youthinkA.G.E.(acute gastroenteritis)
•179 million episodes occur annually
•50% caused by norovirus•NORS started tracking in 2009
•Most illnesses are not tied to a
reported outbreak (1/3000)
http://wwwnc.cdc.gov/eid/article/19/8/13-0482_article.htm
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http://en.wikipedia.org/wiki/Norovirus
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Discovery
The 1968 outbreak of
gastroenteritis at Bronson
Elementary school inNorwalk Ohio prompted a
lot of scientific study.
But it wasn’t until 1972
that Dr Albert Kapikiandiscovered the virus
behind that outbreak.
http://www.niaid.nih.gov/labsandresources/labs/aboutlabs/lid/epidemiologysection/Pages/kapikian.aspx
Dr. Albert Kapikian
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What Can
YOU do?Report unclean
conditions
•Report unclean restrooms to management
•Wash your hands regularly•Stay home when you’re sick (really, no need to
be a hero, let someone else finish those TPS reports.)
http://www.salahqutaishat.com/
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