Nitritos y cáncer del tracto digestivo.

Revisión bibliográfica

Autor: Dra. Zulema FuentesCPHE La Habana

Maestrante en Salud Ambiental

Zaldivar R.: Epidemiology of gastric and colo-rectal cancer in the United States and Chile with particular reference to the role of dietary and nutritional variables, nitrate fertilizer pollution, and N-nitroso compounds.

Zentralbl. Bakteriol. Orig. B 1977. May;164(3):193-217

Zaldivar R, et als. Nitrate nitrogen levels in drinking water of urban areas with high- and low-risk populations for stomach cancer: an environmental epidemiology study.

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978 Oct 30;92(3):227-34.

CNR (1981) The health effects of nitrate, nitrite, and N-nitroso compounds.

Part 1 of a two-part study by the Committee on Nitrite and Alternative Curing Agents in Food.

Report by the US National Research Council, National Academy of Sciences. Washington, DC, National Academy Press.

Jensen OM. Nitrate in drinking water and cancer in northern Jutland, Denmark, with special reference to stomach cancer. Ecotoxicol Environ Saf. 1982 Jun;6(3):258-67.

Gilli G, et als.: Concentrations of nitrates in

drinking water and incidence of gastric

carcinomas: first descriptive study of the

Piemonte Region, Italy. Sci Total Environ.

1984 Mar 1;34(1-2):35-48.

OMS (1985b) Health hazards from nitrate in drinking-water. Report on a WHO meeting, Copenhagen, 5-9 March 1984. Copenhagen, WHO Regional Office for Europe (Environmental Health Series No. 1)

Beresford SA: Is nitrate in the drinking water associated with the risk of cancer in the urban UK?

Int J Epidemiol. 1985 Mar; 14(1): 57-63.

Kyrtopoulos SA, et als: Studies in gastric carcinogenesis. III. The kinetics of nitrosation of gastric-juice components in vitro and their implications for the in vivo formation of N-nitroso compounds in normal and in hypochlorhydric populations.

Carcinogenesis. 1985 Aug;6(8):1141-5.

http://www.ncbi.nlm/.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=4017184

Joossens JV, et als: Nutrition and cancer. Biomed Pharmacother. 1986;40(4):127-38 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=pubmed&dopt=Abstract&list_uids=3539216

Hall CN, et als: Evaluation of the nitrosamine hypothesis of gastric carcinogenesis in precancerous conditions.Gut. 1986 May;27(5):491-8http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3699560

Mettlin C. Dietary factors for cancer of specific sites.Surg Clin North Am. 1986 Oct;66(5):917-29

Bonney GE, et als: Genetic etiology of gastric carcinoma: II. Segregation analysis of gastric pH, nitrate, and nitrite.Genet Epidemiol. 1987;4(2):103-14http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3582957

Hall CN, et als: Evaluation of the nitrosamine hypothesis of gastric carcinogenesis in man. IARC Sci Publ. 1987;(84):527-30 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3679436

Knight TM, et als: The availability of dietary nitrate for the endogenous nitrosation of L-proline. IARC Sci Publ. 1987;(84):518-23.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3679434

Correa P. Modulation of gastric carcinogenesis: updated model based on intragastric nitrosation.IARC Sci Publ. 1987;(84):485-91http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3679427

Andreica V, et als: Contributions to the study of gastric carcinogenesis. Med Interne. 1987 Jan-Mar;25(1):15-24http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3589444

La Vecchia C, et als: A case-control study of diet and gastric cancer in northern Italy. Int J Cancer. 1987 Oct 15;40(4):484-9.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3117710

ECETOC (1988) Nitrate and drinking water. Brussels, European Chemical Industry Ecology and Toxicology Centre (Technical Report No. 27).

Wakabayashi K, et als: Mutagens and carcinogens produced by the reaction of environmental aromatic compounds with nitrite. Cancer Surv. 1989;8(2):385-99http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2696586

Kalble T, et als: The role of nitrate, nitrite and N-nitrosamines in carcinogenesis of colon tumours following ureterosigmoidostomy. Urol Res. 1990;18(2):123-9.

Lauer K.: The history of nitrite in human nutrition: a contribution from German cookery books. J Clin Epidemiol. 1991;44(3):261-4.

Leclerc H,et als: Nitrates in drinking water and cancer. Faculté de Medecine, Lille. Bull Acad Natl Med. 1991 Apr;175(4):651-66

Song PJ, Xu GP.:Study on relationship between occurrence of intragastric lesions and drinking water and nitrate intake via water in the inhabitants from a high-risk area for stomach cancer. Zhonghua Yu Fang Yi Xue Za Zhi. 1991 Jul;25(4):211-3. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=pubmed&dopt=Abstract&list_uids=2624938

Rademacher JJ et als: Gastric cancer mortality and nitrate levels in Wisconsin drinking water. Arch Environ Health. 1992 Jul-Aug;47(4):292-4.

Möller H (1995) Adverse health effects of nitrate and its metabolites: epidemiological studies in humans. In: Health aspects of nitrate and its metabolites (particularly nitrite). Proceedings of an international workshop, Bilthoven (Netherlands), 8-10 November 1994. Strasbourg,

Council of Europe Press, pp. 255-268.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=28515

07

Morales-Suarez-Varela MM, et als: Impact of nitrates in drinking water on cancer mortality in Valencia, Spain. Eur J Epidemiol. 1995 Feb;11(1):15-2.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7489769

OMS (1996) Toxicological evaluation of certain food additives and contaminants. Prepared by the Forty-Fourth Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Geneva, World Health Organization, International Programme on Chemical Safety (WHO Food Additives Series 35).

Bingham SA, et als.: Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis. 1996 Mar;17(3):515-23

Gangolli SD et als: Assessment: nitrate, nitrite and N-nitroso compounds. European journal of pharmacology, environmental toxicology and pharmacology section. 1998 : 292:1-38

van Loon AJ, et als.: Intake of nitrate and nitrite and the risk of gastric cancer: a prospective cohort study. Br J Cancer. 1998 Jul;78(1):129-35http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9662263

Yang CY, et als:. Calcium, magnesium, and nitrate in drinking water and gastric cancer mortality. Jpn J Cancer Res. 1998 Feb;89(2):124-30.

Barrett JH, et als. Nitrate in drinking water and the incidence of gastric, esophageal, and brain cancer in Yorkshire, England. Cancer Causes Control. 1998 Mar;9(2):153-9.

Van Leeuwen JA, et als: Associations between stomach cancer incidence and drinking water contamination with atrazine and nitrate in Ontario (Canada) agroecosystems, 1987-1991.Int J Epidemiol. 1999 Oct;28(5):836-40.

Knekt P, et als: Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: a follow-up study. Int J Cancer. 1999 Mar 15;80(6):852-6.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10074917

Palli D: Epidemiology of gastric cancer: an evaluation of available evidence. J Gastroenterol. 2000;35 Suppl 12:84-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=pubmed&dopt=Abstract&list_uids=8967726

Paik DC, et als: The epidemiological enigma of gastric cancer rates in the US: was grandmother's sausage the cause?Int J Epidemiol. 2001 Feb;30(1):181-2. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=pubmed&dopt=Abstract&list_uids=11171883

Weyer PJ, et als: Municipal drinking water nitrate level and cancer risk in older women: the Iowa Women's Health Study.

Epidemiology. 2001 May;12(3):327-38.

Sandor J, et als.: Association between gastric cancer mortality and nitrate content of drinking water: ecological study on small area inequalities. Eur J Epidemiol. 2001;17(5):443-7

Bingham SA, et als: Effect of white versus red meat on endogenous N-nitrosation in the human colon and further evidence of a dose response. J Nutr. 2002 Nov;132(11 Suppl):3522S-3525S

Cross AJ, et als.: Red meat and colorectal cancer risk: the effect of dietary iron and haem on endogenous N-nitrosation. IARC Sci Publ. 2002;156:205-6.

Gulis G, et als.: An ecologic study of nitrate in municipal drinking water and cancer incidence in Trnava District, Slovakia. Environ Res. 2002 Mar;88(3):182 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12051796

Archer DL: Evidence that ingested nitrate and nitrite are beneficial to health.J Food Prot. 2002 May;65(5):872-5.Related Articles, Links http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12030305

Tari A, et als: Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients? Dig Dis Sci. 2003 Sep;48(9):1730-6.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14560992

Engel LS, et als:. Population attributable risks of esophageal and gastric cancers. J Natl Cancer Inst. 2003 Sep 17;95(18):1404-13.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=13130116

Kleinjans JC, et als: Contamination of drinking water: evaluation of genotoxic risk in human populations. Epidemiology. 2003 Nov;14(6):640-9

Iijima K, et als. Novel mechanism of nitrosative stress from dietary nitrate with relevance to gastro-oesophageal junction cancers. Carcinogenesis. 2003 Dec;24(12):1951-60http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12970071

Kodama K, et als: Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk? Eur J Gastroenterol Hepatol. 2003 Sep;15(9):987-93.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=pubmed&dopt=Abstract&list_uids=12923371

GEO América Latina y el Caribe. Perspectivas para el Medio Ambiente 2003 PNUMA Oficina Regional para América Latina y el Caribe, México, D. F., México. ISBN: 92-807-2295-6.

Turkdogan MK, et als: I. Dietary nitrate and nitrite levels in an endemic upper gastrointestinal (esophageal and gastric) cancer region of Turkey. Turk J Gastroenterol. 2003 Mar;14(1):50-3. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14593538

De Roos AJ ,et als. Nitrate in public water supplies and the risk of colon and rectum cancers. Carcinogenesis. 2003 Dec;24(12):1951-60.

Lee WJ, et als: Agricultural pesticide use and adenocarcinomas of the stomach and oesophagus.Occup Environ Med. 2004 Sep;61(9):743-9.

Tran GD, et als:Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China.Int J Cancer. 2005 Jan 20;113(3):456-63

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15455378&dopt=Abstract