NIH Training and Fellowship NIH Training and Fellowship Programs, and Loan RepaymentPrograms, and Loan Repayment

Henry Khachaturian, Ph.D.NIH Extramural Program Policy Officer

Director of Policy, NIH Loan Repayment ProgramsOffice of Extramural Research, NIH

Email: hk11b@nih.gov

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NIH Office of Extramural Research

EB2013/FASEB – April 2013

National Institutes of Health

Our mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce the burdens of illness and disability.

World’s largest source of funding for biomedical research

Support more than 300,000 research personnel at over 3,000 universities and research institutions

27 Institutes and Centers (ICs) with specific research agendas

Research Project Grants:53.0%

Intramural Research:

10.0%

R&D Contracts:11.0%

Research Centers:

10.0%

Career Dev. 2.1%

Other Research:3.5%

All Other:2.0%

Research Mgmt & Support:

5.0%

Research Training:

2.5%

$767,132 Training $626,778 Career$1,393,910

$767,132 Training $626,778 Career$1,393,910

NIH Budget Office: http://officeofbudget.od.nih.gov/index.htm

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FY 2015 President’s Budget: $30,361,653

NRSA Individual and Institutional Training Awards Individual Fellowships Research Career Development Awards Fellowship Review Criteria NIH Loan Repayment Programs

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NIH New Investigators Programs

Predoctoral Individual NRSA (F31)Predoctoral Individual NRSA (F31)Predoctoral Individual MD/PhD NRSA Predoctoral Individual MD/PhD NRSA

(F30)(F30)Postdoctoral Institutional Training Postdoctoral Institutional Training (T32)(T32)Postdoctoral Individual NRSA (F32)Postdoctoral Individual NRSA (F32)

Small Grant Small Grant (R03) (R03) Research Project Research Project Grant (R01)Grant (R01)

Independent Scientist Award (K02)Independent Scientist Award (K02)

Senior Scientist Award (K05Senior Scientist Award (K05) )

Career StageCareer Stage ‘‘Formal’ Training/Career AwardsFormal’ Training/Career Awards

GRADUATE/GRADUATE/MEDICALMEDICALSTUDENTSTUDENT

POSTPOSTDOCTORALDOCTORAL

EARLYEARLY

MIDDLEMIDDLE

SENIORSENIOR

CA

REER

CA

REER

Predoctoral Institutional Training Grant (T32)Predoctoral Institutional Training Grant (T32)

NIH Pathway to Independence (PI) Award NIH Pathway to Independence (PI) Award (K99/R00)(K99/R00)Mentored Research Scientist Development Mentored Research Scientist Development Award (K01)Award (K01)Mentored Clinical Scientist Development Mentored Clinical Scientist Development Award (K08)Award (K08)Mentored Patient-Oriented RCDA (K23)Mentored Patient-Oriented RCDA (K23)Mentored Quantitative RCDA (K25)Mentored Quantitative RCDA (K25)

Midcareer Investigator Award in Midcareer Investigator Award in Patient-Oriented Research (K24) Patient-Oriented Research (K24) Exploratory/Exploratory/

Develop-ment Develop-ment Grant (R21) Grant (R21)

Pre-BacPre-Bac Pre-Bac Institutional Training Grant (T34)Pre-Bac Institutional Training Grant (T34)

Training & Career Development Support 2014

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‘‘Informal’ Training Informal’ Training and Careerand CareerDevelopment on Development on RPGs and RPGs and SupplementsSupplements

Research AwardsResearch Awards

$767M$767M

$627M$627M

Advice for Mapping Your Career With NIH

Review Institute/Center (IC) priorities and goals. Each IC has a research training and career development program.

Learn the NIH application and review process

Identify the grant programs offered by each IC

Make early contact with program officers

Find innovative, well-respected mentors and collaborators

Study successful grant applications- talk to your mentor

Propose your best and most creative ideas

Career Path for a Research Doctoral Degree (Ph.D. or equivalent)

Graduatestudent

IndependentPIPh.D.

Faculty Position

T32 F31F32or

T32K22 R01 R37K02

T32- Institutional training grant (NRSA)-has pre-& postdoc slotsF30 and F31- Individual predoc fellowship (NRSA) (some ICs only support Diversity F30/31s)F32- Individual postdoc fellowship (NRSA)F33- Sr. postdoc fellowship (NRSA)R03- Small GrantR21- Exploratory/Developmental Research GrantR01- Research grant

F33R21R03

Diversity Supplements

K99/R00

PsUs

K02- Independent Scientist AwardK22- Research Scholar Development AwardK99/R00- Pathway to Independence AwardR37- Merit awardP01- Program Project GrantU01- Cooperative Agreement

Career Path for a Clinical Docotoral Degree (M.D. or equivalent)

Medical Student

IndependentPIM.D.

FacultyPosition

T35T32or

F32R01 R37

K08or

K23K22

Clinical Training

K02 K24

T35- Short-term Training Grant for Health Professional StudentsF33- Sr. Postdoctoral Fellowship (NRSA)K08- Mentored Clinical Scientist Development AwardK23- Mentored Patient-Oriented Research Career Development AwardK24- Mid-Career Investigator in Patient-Oriented ResearchK07, K12- IC specificPlus all mechanisms from Ph.D. track

F33R21K99/R00

Diversity Supplements

F30

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• Established by the NRSA Act of 1974.̶� Section 487 of PHS Act; Regulations at 42 CFR 66.

• Replaced all previous NIH training authority.

• Name change legislation passed August 2002.

• Supported by 22 of the 24 awarding NIH Institutes and Centers (FIC and NLM have own authority).

• Supported by the Agency for Health Care Research and Quality (AHRQ) and the Health Resources Services Administration (HRSA).

• 2 types of awards:̶� Institutional, e.g. T32, T34, T35, T90/R90.̶� Individual, e.g. F30, F31, F32, F33.

Research Training Awards Authority

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National Research Service Award Policies

Policies that apply to both Training Grants and Fellowships…

Guidelines:

• NIH Grants Policy Statement, Kirschstein—NRSA Section: http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_Part10.htm#_Toc54600187

• Program Announcements & Other Information: http://grants.nih.gov/training/nrsa.htm

Citizenship Requirements Citizenship Requirements

• Must be Citizen, non-citizen national, or lawfully admitted for permanent residence

• Permanent Residents:– Fellowships: Must have been admitted as a

Permanent Resident by the time of award– Training Grants: Must have been admitted as a

Permanent Resident at time of appointment

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Degree Requirements

• Pre-Baccalaureate: Currently enrolled as an honors undergraduate at designated institutions (MARC and COR trainees).

• Predoctoral: Must have a baccalaureate degree and be enrolled in doctoral program leading to PhD or equivalent, or dual research/clinical doctorate such as the MD/PhD.

• Postdoctoral: Must have a PhD or MD or comparable doctoral degree from an accredited domestic or foreign institution.

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NRSA Limitationsions

Duration of Support:– Predoc: 5 years* – Postdoc: 3 Years– Aggregate limits apply: any combination from individual

and/or institutional awards

Exceptions:– Physicians/Clinicians (*combined-degree F30 allows 6

years) – Interruptions (break in service)– Waiver request requires IC prior approval

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Ruth L. Kirschstein National Research Service AwardsRuth L. Kirschstein National Research Service Awards

Overview:

The overall goal of the NIH Ruth L. Kirschstein National Research Service Award (NRSA) program is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs.

NRSA Opportunities: Training grants (Ts): Multi-

slot awards that are used to support research training activities for several individuals.

Fellowships (Fs): Awards for graduate students working on a doctoral degree and researchers who have just earned their doctorates (postdocs).

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NRSA FellowshipsNRSA Fellowships

Overview:

Awarded to Predoctoral or Postdoctoral fellows who are working with mentors.

Training can be at domestic or foreign institutions.

Opportunities in basic and/or clinical research.

Open to any scientific area within the NIH scientific mission.

PhDs and MD/PhDs receive most of the awards.

F-Kiosk: http://grants.nih.gov/training/F_files_nrsa.htm

Core Review Criteria:1. Fellowship Applicant – Academic

record and training, publications, etc.

2. Sponsors, Collaborators, and Consultants

3. Research Training Plan4. Training Potential5. Institutional Environment &

Commitment to Training

Additional Review Consideration:1. Training in the Responsible

Conduct of Research

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F30 and F31 Predoctoral FellowshipsF30 and F31 Predoctoral Fellowships

Overview:

Support Predoctoral Fellows during graduate (possibly medical) training.

F30 (MD/PhD) may support up to 6 years of training.

F31 is limited to 5 years total.

Promising doctoral candidates who will be performing dissertation research.

Some Institutes and Centers only support Diversity F31s.

Fellows may not change the scope, move fellowship, or change mentor without prior NIH approval!

Program Features:

•Stipend: FY 2015: $22,920

•Tuition/Fees: 60% of requested tuition, capped

at $16,000 ($21,000 for MD/PhD programs)

•Institutional Allowance: $4,200 Includes health insurance

•Travel Allowance: Part of IA

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F32 Postdoctoral FellowshipsF32 Postdoctoral Fellowships

Overview:Support Postdoctoral research training.

Promising fellows with the potential to become productive, independent investigators in scientific health-related research fields relevant to the missions of NIH Institutes & Centers.

NRSA support for up to 3 years total. Awardees incur two years of payback.

Repay the 1st year by staying in research a 2nd year

Fellows may not change the scope, move fellowship, or switch mentor without prior NIH approval!

Program Features:

•Stipends: FY 2014: $42,000 (Level-0) to

$55,272 (Level-7)

•Tuition/Fees: 60% of requested tuition, capped

at $4,500 ($16,000 for those seeking another doctoral degree)

•Institutional Allowance: $7,850 Includes health insurance

•Travel Allowance: Up to $1,000

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Kirschstein-NRSA training grants and fellowships Pre- and Post-Doctoral full-time training positions

awarded

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Kirschstein-NRSA pre-doctoral fellowships (F31s) Applications, awards, and success rates

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Kirschstein-NRSA post-doctoral fellowships (F32s) Applications, awards, and success rates

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My Application

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$$$

Center for Scientific Review

Assigns IRG in CSR or IC

Scientific Review Group

Evaluates Scientific Merit

Institute or Center (IC)

Evaluates Relevance

Advisory Council

Recommends Action

IC DirectorAllocates Funds

PI / Institution Submits application

Conduct Research

Revision / Resubmission

The NIH Review Process

Fellowship Applicant:Fellowship Applicant: Are the applicant’s academic record and research

experience of high quality? Does the applicant have the potential to develop into an

independent and productive researcher in biomedical, behavioral or clinical science?

Does the applicant demonstrate commitment to a career as an independent researcher in the future?

Fellowship Review Criteria (1 of 5)

Sponsors, Collaborators, and Consultants:Sponsors, Collaborators, and Consultants: Are the sponsor(s’) research qualifications (including recent publications) and

track record of mentoring individuals at a similar stage appropriate for the needs of the applicant?

Is there evidence of a match between the research interests of the applicant and the sponsor(s)? Do the sponsor(s) demonstrate an understanding of the applicant’s training needs as well as the ability and commitment to assist in meeting those needs?

Is there evidence of adequate research funds to support the applicant’s proposed research project and training for the duration of the fellowship?

If a team of sponsors is proposed, is the team structure well justified for the mentored training plan, and are the roles of the individual members appropriate and clearly defined?

Are the qualifications of any collaborator(s) and/or consultant(s), including their complementary expertise and previous experience in fostering the training of fellows, appropriate for the proposed research project?

Fellowship Review Criteria (2 of 5)

Research Training Plan:Research Training Plan: Is the proposed research plan of high scientific quality, and

is it well integrated with the proposed training plan? Is the research project consistent with the applicant’s stage

of research development? Is the proposed timeframe feasible to accomplish the

proposed research training? Based on the sponsor’s description of his/her active

research program, is the applicant’s proposed research project sufficiently distinct from the sponsor’s funded research for the applicant’s career stage?

Fellowship Review Criteria (3 of 5)

Training Potential:Training Potential: Do the proposed research project and training plan have

the potential to provide the applicant with the requisite individualized and mentored experiences that will develop his/her knowledge and research and professional development skills?

Does the training plan take advantage of the applicant’s strengths and address gaps in needed skills? Does the training plan document a clear need for, and value of, the proposed training for the applicant?

Does the proposed research training have the potential to serve as a sound foundation that will clearly lead the fellow to an independent and productive research career?

Fellowship Review Criteria (4 of 5)

Institutional Environment & Commitment to Training:Institutional Environment & Commitment to Training: Are the research facilities, resources (e.g. equipment,

laboratory space, computer resources, subject populations), and training opportunities (e.g. seminars, workshops, professional development opportunities) adequate and appropriate?

Is the institutional environment for the applicant’s scientific development of high quality?

Is there appropriate institutional commitment to fostering the applicant’s mentored training toward his/her research career goals?

Fellowship Review Criteria (5 of 5)

Resources:Resources: NIH Extramural Training Mechanisms:

http://grants1.nih.gov/training/extramural.htm

Ruth L. Kirschstein National Research Service Award (NRSA): http://grants1.nih.gov/training/nrsa.htm

NIH Career Development Awards: http://grants1.nih.gov/training/careerdevelopmentawards.htm

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NIH Office of Extramural Research

Extramural Loan Repayment Programs

Clinical Research

Pediatric Research

Health Disparities Research

Contraception and Infertility Research

Clinical Research for Individuals from Disadvantaged Backgrounds

In exchange for a two-year research commitment, NIH repays qualified educational debt up to $35,000 per year. Payments made to lenders.

Research must be funded by a domestic nonprofit, university or U.S. federal, state or local government entity.

Recipients conduct research for an average of at least 20 hours per week over a quarter.

Tax liability on the loan payments is partially offset.

Apply September 1 – November 15.

1,600 researchers funded each year. Success rate is 40 percent for new applicants and 70 percent for renewals.

Additional Information: http://www.lrp.nih.gov/

Extramural Loan Repayment Programs