nifa food safety portfolio: an overview · –food safety, nutrition and health (15%) –practical...
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NIFA Food Safety Portfolio:
an overview
Max Teplitski, Ph.D.
National Program Leader
Food Safety and Microbiology
USDA NIFA IFSN
Opportunities and challenges in
Food Safety and Food Security
2002 (tomatoes), 141 cases
2006 (tomatoes), 183 cases
2008 (cantaloupes), 51 cases
2009 (alfalfa sprouts), 235 cases
2010 (alfalfa sprouts), 140 cases
2011 (sprouts), 25 cases
2008 (tomatoes/peppers), 1442 cases
2012 (cantaloupes), 261 cases
2013 (cucumbers), 84 cases
2014 (cucumbers), 257 cases
Identifying, characterizing and mitigating such
foodborne hazards is one of the goals of
NIFA’s Food Safety portfolio
Survival and internalization of human pathogens in leafy greens University of California - Davis
Images courtesy of Dr. M. Melotto
Survival and internalization of human pathogens in leafy greens (2) University of California - Davis
Survival and internalization of human pathogens in leafy greens (3) University of California - Davis
• Salmonella (not E.coli) evolved to evade
plant defense responses
• Weakened plant defense responses lead
to an increase (1-2 log/cm2) in human
pathogens • Lettuce cultivars differ (1-1.5 log) in
susceptibility to Salmonella
Dissemination of pathogens with surface water: an intervention Cornell University
Images courtesy of Dr. R. Ivanek
Dissemination of pathogens with surface water: an intervention (2) Cornell University
•Chance of contamination is higher
in furrow plots than in drip-irrigated
plots
•UV irradiation reduced pathogen
load by 100-1,000 fold
•Water treatment with urea reduced
pathogen load by 100-1,000 fold
Focus of NIFA Food Safety programs
• Prevention, detection, and control of food and waterborne pathogens
• Ecology of food-borne pathogens
• Plant-pathogen interactions
• Improved processing to promote food safety
• Improving safety of fresh produce
• Ensuring safety of production systems, including organic agriculture
• Systems approach for mitigation of antibiotic resistance
• Interactions between food safety, nutrition and human health
• Providing food safety education
Agriculture and Food Research Initiative
• Peer-reviewed competitive grants program
• FY15 funding: ~$274 million
• Projects funded: 554
– Plant health and production, plant products (~29%)
– Bioenergy, natural resources, and environment (17.5%)
– Food safety, nutrition and health (15%)
– Practical education to improve the lives of Youth, Consumers and Families (12%)
– Animal health and production, animal products (~11%)
– Agriculture economics and rural communities (10%)
– Agriculture systems and technology (5%)
Antimicrobial resistance and mitigation strategies in beef cattle University of Florida
Images by Dr. KC Jeong
Antimicrobial resistance and mitigation strategies in beef cattle (2) University of Florida
Antimicrobial resistance and mitigation strategies in beef cattle (3) University of Florida
Antimicrobial resistance and mitigation strategies in beef cattle (4) University of Florida
Images by Dr. KC Jeong
Vaccine to reduce Campylobacter in chickens University of Arizona
• Recombinant Salmonella Vaccine (oral and spray) reduced
Campylobacter load by 100-10,000 CFU/g feces in vaccine
trials
• U.S. Patent (approved), pending in Europe, China and Brazil
• Stakeholder survey to collect current interventions and
awareness of new FSIS performance standards
• Dynamic simulation model representative of a broiler
production system with inputs from stakeholders to allow
prediction of efficacy and costs of various interventions
Images courtesy of Dr. B.Law
Novel Salmonella control practices and integrated education NC State University
Images courtesy of Dr. H. Hassan
Novel Salmonella control practices and integrated education (2) NC State University
• Prebiotic GOC reduced Salmonella
load by 2-2.5 log (99% reduction)
• Vaccination reduced Salmonella load
by 3-3.5 log (99.9% reduction)
• GOC modulated gut microbiota (more
Firmicutes, Bacilli) to resist Salmonella
• Novel bacteriocin-producing
Lactobacillus isolated
• Developed education and software
programs about food-borne pathogens
and food safety for K-12, 4-H and the
public
Controlling Lawsonia infections of pigs to reduce Salmonella shedding: an intervention trial
University of Minnesota
Images courtesy of Dr. R. Isaacson
Controlling Lawsonia infections of pigs to reduce Salmonella shedding: an intervention trial (2)
University of Minnesota
•Lawsonia intracellularis increases shedding of
Salmonella enterica
•Vaccination against L. intracellularis will reduce
shedding of S. enterica
•Challenge with S. enterica reduced microbiota
but either challenge with L. intracellularis or use of a
live attenuated vaccine increased microbial diversity
Recovery of low-tolerance pathogens from foods and water University of Hawaii-Manoa
• Electroflotation to achieve truly real time detection of trace
contaminants with portable biotechnology
Images courtesy of Dr. D. Jenkins
Rapid food safety test with phage-conjugated nanoparticles Cornell University
Images courtesy of Dr. S. Nugen
Engineered water nanostructures (EWNS) to inactivate pathogens in fresh produce
Harvard University
Science-Based Messages to Improve Consumers’ Storage, Handling, and Preparation of Poultry and Poultry Products
Tennessee State
• Bacteria survive on some food packages
for months
• Youth are willing to share food safety
information with parents (74% increase in
youth’s knowledge, 64% willing to share
with parents)
• Adding food safety steps within recipe
instructions increases safe food handling
behaviors by 82-94%
• Type of kitchen lighting impacts visual
perception of meat doneness
http://www.tnstate.edu/tsuaged/peepcurriculum.aspx
Images courtesy of Dr. S. Godwin
USDA-NIFA FDA-CFSAN
FSMA Implementation Partnership
FSMA Framework for Industry Curriculum Development and Dissemination
Overall Vision
Add-on curricula
NIFA Food Safety Programs
• Approximately $40 million each year
• Range from $300,000 to $5 million
• Conference grants – up to $50,000
• International collaborations
• Training of future work force