news you can use… pete koval, pharmd megan shah, pharmd candidate cone health family medicine july...
TRANSCRIPT
News You Can Use…
Pete Koval, PharmD
Megan Shah, PharmD Candidate
Cone Health Family Medicine
July 2015
Drug Launched
• Risedronate, generic for Actonel, is now available• Risedronate is used for the treatment and
prevention of osteoporosis and treatment of Paget’s disease.
• Available as 5 mg, 30 mg, and 35 mg tablets
06/2/2015 Pharmacy Times
Trial Review
• IMPROVE-IT trial shows cardiac benefit of adding ezetimibe 10 mg to simvastatin 40 mg after ACS• Simvastatin/ezetimibe reduced CV events by
~7% vs. simvastatin monotherapy (NNT=50)• Baseline LDL of 94 mg/dl was reduced to 54
g/dl with simvastatin/ezetimibe and 70 mg/dl with simvastatin alone.
06/4/2015 N Engl J Med
Pharmacy Business
• CVS Health bought Target pharmacies and clinics• Target pharmacies will operate under CVS
name inside Target stores.• Target clinics will be rebranded as
MinuteClinic
06/15/2015 NY Times
New Indication
• Zomig (zolmitriptan) nasal spray has been FDA approved for treatment of migraines with or without aura in pediatric patients >12 years of age• Previously was only indicated for age >18.• Starting dose for pediatric patients is 2.5 mg
daily with a max dose of 10 mg daily.
06/16/2015 Medscape
New Drug Approval
• Kengreal (cangrelor) gained FDA approval to prevent blood clots in patients undergoing PCI• Intravenous antiplatelet drug (P2Y12
inhibitor)• Administered as a 30 mcg/kg bolus injection,
followed by a 4 mcg/kg/min infusion for 2 to 4 hours.
06/22/2015 FDA.gov
FDA Warning
• FDA issued a warning of permanent loss of skin color for Daytrana (methylphenidate) patch.• Skin condition is called chemical leukoderma• Time of onset ranges from 2 months to 4
years
06/24/2015 FDA.gov