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    Prof. Dr.Mohd Ismail Noor FASc, FIUNS

    President, Malaysian Association for the study ofObesity (MASO)

    Department of Nutrition and DieteticsFaculty of Allied Health SciencesUniversiti Kebangsaan Malaysia

    Kuala Lumpur

    Obesity Epidemic: Issues andChallenges in Malaysia

    Nestle Media Workshop, 21 July 2006. Cyberjaya

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    OBESITY:Issues and Challenges

    Global and regional scenario

    BMI Classification issues

    Prevalence of Obesity

    Etiology of Obesity

    Health Implication and cost

    Combating Obesity

    Conclusion

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    We are unanimous in our belief that OBESITYis a hazard

    to health and a detriment to well-being. It is common

    enough to constitute one of the most important MEDICAL& PUBLIC HEALTH problem of our time, whether we

    judge importance by a shorter expectation of life, increased

    morbidity, or cost to the community in terms of both

    MONEY andANXIETY.Professor Waterloo

    MRC Report 1976

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    Disease of the New MillenniumIOTF, 1998

    Obesity: a time bomb to be defused

    Bray, 2000 Treatment of obesity: Mission Impossible

    Golay, 2000

    Overweight and Obesity: A new nutritionEmergency?

    SCN, WHO 2005

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    Global epidemic of obesity

    1.7 billion

    1.1 billion

    >300 million

    IOTF (2005)

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    Obesity Rates Could Double In 30 Years

    %

    ofpo

    pulatio

    nBMI>30

    IOTF, 1998

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    Overweight and Obesity prevalence among adults in Asia

    Country Year Sex OWT

    (%)

    Obese

    (%)

    Source

    Iran 1999 M

    F

    44.1

    51.0

    10.2

    26.4

    Ghassemi*

    2002

    Malaysia 1996 M

    F

    15.1

    17.9

    2.9

    5.7

    Ismail et al*2002

    Korea 1998 M

    F

    24.3

    23.5

    1.7

    3.0

    Lee et al*

    2002

    Japan 1995 MF

    22.318.3

    2.23.1

    Popkin etal*, 2002

    China 1997 M

    F

    12.0

    13.8

    2.5

    2.4

    Du et al*

    2002

    Thailand 1996 M

    F

    13.2

    25.0

    ?

    ?

    Kosulwat*

    2002

    Philippines 1993 M

    F

    11.0

    11.8

    1.7

    3.4

    Solon*

    2002

    Hong Kong 1997 M

    F

    33.0

    (M&F)

    5.4

    7.0

    Janus

    1997

    India 1998 M

    F

    4.0

    4.0

    0.5

    0.5

    Shetty*

    2002

    *Obesity Review, August 2002

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    Obesity is a key & spreading issue in developed &

    developing countries (BMI>30.0)

    Ismail, 1998

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    Prevalence of overweight and obesity in selected

    Asian countries ( Urban vs Rural )

    Country Year Area OWT

    (%)

    OBESE

    (%)

    Source

    Iran 1999 U

    R

    28.0

    19.9

    12.4

    6.8

    Ghassemi*

    2002

    Malaysia 1996 U

    R

    17.4

    15.5

    4.5

    4.3

    Ismail et

    al,* 2002

    India 1998 U

    R

    10.9

    7.3

    1.1

    0.8

    Shetty*

    2002

    *Obesity Review, August 2002

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    Classification of Body Weight in Adults According to

    Body Mass Index, BMI

    Classification BMI, kg/m2 Risk of co-morbidities

    Underweight < 18.5 Low (but risk of other clinicalproblems increased)

    Normal range 18.5 24.9 Average

    Overweight > 25.0

    Pre-Obese 25.0 29.9 Increased

    Obese Class I 30.0 34.9 Moderate

    Obese Class II 35.0 39.9 Severe

    Obese Class III > 40.0 Very severe

    WHO, 1998

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    The Asia-Pacific

    perspective:

    Redefining

    obesitytreatment

    and its

    February 2000

    World Health Organization

    Western Pacific Region

    IASO INTERNATIONAL ASSOCIATION FOR THE STUDY OF OBESITY

    International Obesity TaskForce

    IOTF (2000)

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    Proposed Classification of Weight by Body Mass Index

    in Adult Asians

    Classification BMI, kg/m2

    Risk of co-morbidities

    Underweight < 18.5 Low (but risk of other clinicalproblems increased)

    Normal range 18.5 22.9 Average

    Overweight > 23.0

    At Risk 23.0 24.9 Increased

    Obese Class I 25.0 29.9 ModerateObese Class II > 30.0 Severe

    IOTF, 2000

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    Are population specific BMI cut-off points for overweight and obesity

    necessary?

    Recent studies in Hong Kong, Singapore, Indonesia and Japan suggestedthat these populations have a relatively high body fat % at low BMI

    Meta-analysis in Asian populations revealed:

    - Caucasian prediction equation cannot be applied to all Asian

    populations.

    - In general, both male and female Asians have more body fat

    then their European counterparts of the same age and BMI.

    - Calculated BMI cut-off points vary considerably from (21.6

    25.9) for

    overweight and from (26.3- 30.8) for obesity

    WHO Consultation, July 2002.

    Issues

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    Asian BMI action point - BMI>23

    Source: THE LANCET Vol 363 January 10, 2004 www.thelancet.com

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    = Suggested cutpoints for reporting population BMI distribution and specific action

    levels for populations and individuals

    overweight Obese I Obese II Obese III

    Ranges for

    determining

    public health and

    clinical action

    levels based on

    BMI

    underweight

    16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40

    Low to Moderate Risk

    Moderate to High Risk

    High to Very High Risk

    WHO

    classification

    Lancet, 2004

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    Waist Circumference

    Correlatesabdominal fat distribution

    and associated ill health.

    Increased risk: Men > 94 cm (37 in.)

    Women > 80 cm (32 in.)

    Lower values have been proposed for

    Asian man

    ( 90cm for men and 80cm for women)

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    The Obesity Epidemic

    Malaysian scene

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    NATIONAL HEALTH AND MORBIDITY

    SURVEY (1996-97)

    2.9

    5.7

    4.5

    4.3

    5.1

    3.5

    5.0

    15.1

    17.9

    17.4

    15.5

    17.3

    16.0

    20.6

    Male

    Female

    Urban

    Rural

    Malay

    Chinese

    Indian

    Obese

    (BMI > 30 kg/m2)

    (%)

    Overweight

    (BMI 25-29.9 kg/m2)

    (%)

    Adults

    Lim et al, 2000

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    Prevalence of Obesity in Malaysi

    0.0

    2.0

    4.0

    6.0

    8.0

    10.0

    12.0

    14.0

    16.0

    Men Women

    Obes

    ity%(

    BMI>30)

    NHMS 1996

    MANS 2002/2003

    NHMS National Health & Morbidity Survey- 1996

    MANS Malaysian Adults Nutrition Survey- 2002/03

    PREVALENCE AND TRENDS OF OBESITY1 AMONGST MALE

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    PREVALENCE AND TRENDS OF OBESITY1 AMONGST MALE

    ADOLESCENTS IN SECONDARY SCHOOLS

    1990 1997

    School n Obese

    no.

    % n Obese

    no.

    %

    Section 16, Shah

    Alam

    1383 3 0.2 731 51 7.0

    Seaport, Kelana

    Jaya

    1213 12 1.0 1224 71 5.8

    SSAAS, Shah

    Alam

    1039 9 0.9 936 57 6.1

    Subang Jaya 1119 11 1.0 1127 48 4.3

    Total 4754 35* 0.7 4018 227** 5.7

    Ratio 1:136 1:18

    1 WHO (1995), Ismail & Vickneswary (1998)

    **Malay 140 (62%), Chinese 56 (25%), Indian 31 (13%)

    *Malay 15 (43%), Chinese 13 (37%), Indian 7 (20%)

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    10.9

    10.7 10.1 10.5

    6.0

    5.5

    6.3

    5.7

    0

    2

    4

    6

    8

    10

    12

    North Central South East

    Region

    Percent(

    Prevalence of Overweight & Obesity according to

    Regions in Peninsular Malaysia (6-12 years)

    n = 11264

    n=2845n = 2875 n = 2825 n = 2719

    UKM/Nestle study 2002

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    4.9

    6.6

    9.0

    10.0

    12.6

    16.9

    15.4

    4.5

    6.7

    7.9

    11.912.4

    13.8

    15.5

    0

    2

    4

    6

    8

    10

    12

    14

    16

    18

    6 7 8 9 10 11 12

    Age(Years)

    Perce

    nt(%)

    Male Female

    Prevalence of Overweight in Children

    according to age & sex

    N = 11264

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    10.8

    5.9

    10.3

    5.8

    0

    2

    4

    6

    8

    10

    12

    Overweight Obese

    Per

    cent(%)

    Male Female

    Prevalence of Overweight & Obesity according to Sex

    n = 11264

    n = 1188

    n = 661

    UKM/Nestle study 2002

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    4.95.1 5.0

    5.9 5.8

    7.48.1

    5.1

    5.75.3 5.3

    6.1

    6.77.0

    0

    1

    2

    3

    4

    5

    6

    7

    8

    9

    6 7 8 9 10 11 12

    Age (Years)

    Percent(%

    Male Female

    Prevalence of Obesity in Children according to age

    and sex

    N = 11264

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    10.510.1

    11.7

    6.2

    4.7

    6.7

    0

    2

    4

    6

    8

    10

    12

    14

    Malay Chinese Indian

    Ethni

    Perce

    nt(%)

    Overweight Obese

    Prevalence of Overweight & Obesity according to

    ethnic groups

    n = 11264

    n = 7803n = 2511 n = 950

    UKM/Nestle study2002

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    Prevalence of overweight/obesity1among

    children in Asia Pacific

    0 5 10 15 20

    Thailand*+

    Taiwan*

    South Korea

    Singapore@

    Philippines***

    NewZeal.**

    Malaysia#

    Japan*@

    Hong Kong*

    China

    Australia

    %

    Boys

    Girls

    1IOTF, *>120%

    ** 95th /WHO 1995

    ***85th, NHANES

    # Malaysia: Cole et al 2000;

    + Thailand: both sexes

    @ Red bar for younger, purple older age groups

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    Prevalence of overweight and obesity in

    10-year-old boys and girls

    Country Boys Girls

    Sample % Overweight* Sample % Overweight*

    Italy 334 29.6 344 31.4

    Japan 392 27.8 384 18.5

    Singapore 1660 25.5 1584 17.6

    Germany (Munich) 314 22.9 309 25.9

    Hungary 117 20.5 115 13.9

    Hong Kong 661 20.3 623 10.1

    Germany (Dresden) 415 15.4 369 17.6

    Germany (Jena) 114 10.5 122 13.9UK 1222 9.5 1113 14.4

    Netherlands 847 4.5 897 6.7

    MALAYSIA 1046 18.4 943 18.5

    * Figures includes overweight and obese using the IOTF standarddefining total overweight as

    -

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    Influences on Energy Balance and Weight Gain

    ENVIRONMENTAL & SOCIETAL INFLUENCES

    Individual / Biological

    SusceptibilityDietary & Physical

    Activity Patterns

    BODY FAT STORES

    ENERGY REGULATIONINTAKE EXPENDITURE

    FAT

    CHO

    PROTEIN

    BMR

    TEF

    ACTIVITY

    STABLE

    WEIGHTGAIN LOSS

    WHO, 1998

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    ENVIRONMENTAL MODIFIERS IN WEIGHT-

    REGULATION POTENTIAL THAT INFLUENCE

    1.CHOICE & AMOUNT

    OF FOOD CONSUMED

    2.CHOICE & AMOUNT OF

    PHYSICAL ACTIVITY

    availability

    cost

    energy density

    fat

    sugar

    palatability variety

    portion size

    access to recreational sports

    nonmotorized form of

    transportation

    television

    labour-saving devices

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    The Global Paradox

    While wealthy industrialized nations spend

    significant amount of money to convince their

    populations to replace dietary fats with a

    simpler diet based on grains, vegetables andfruits,

    the developing nations use their growing

    incomes to replace their traditional diets, rich

    in fibers and grains, with diets that include agreater proportion of fats and sugars.

    Drewnowski & Popkin, 1997

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    2200

    2300

    2400

    2500

    2600

    2700

    2800

    2900

    3000

    3100

    1961

    -63

    1964

    -66

    1967

    -69

    1970

    -72

    1973

    -75

    1976

    -78

    1979

    -81

    1982

    -84

    1985

    -87

    1988

    -90

    1991

    -93

    1994

    -9619

    97

    Calories

    Protein

    Fat

    100

    90

    80

    70

    60

    50

    40

    Changes in availability of calories, protein and fat in Malaysia, 1961-1997

    Source: Food Balance Sheet of Malaysia (FAO)

    100%

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    Changes in sources of calories in Malaysia, 1961-1997

    Food Balance Sheet FAO (1961-1997)

    0%

    10%

    20%

    30%

    40%

    50%

    60%

    70%

    80%

    90%

    100%

    1961-63 1970-72 1979-81 1988-90 1997

    Cereals Starchy roots Vegetables & fruits

    Pulses Meat, fish, egg Milk-excl butter

    Sweeteners Oils & fats Miscellaneous

    %

    of

    C a

    l orie s

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    Summary on Nutrition Practice: Fast Foods

    Majority 50% once a month

    20% once a week

    5% more than twice a week

    15% everyday!!

    Twice as many rural children compared to

    urban had never taken fast foods

    By ethnic: percentage of Indians who had nevertaken fast foods were higher than

    Malays and Chinese

    UKM/Nestle report (2002)- 11500 Primary school children in Peninsular Malaysia

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    Know your Fast FoodsKnow your Fast FoodsKnow your Fast FoodsKnow your Fast Foods

    A quarter-pound cheeseburger, largefries,

    and a 16 oz. sodaprovides

    1,166 calories

    51 g fat95 mg cholesterol

    1,450 mg sodium

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    Physical Activity Past Present

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    DAILY ACTIVITY PATTERNS OF OBESE SUBJECTS

    (min/day)

    0

    100

    200

    300

    400

    500

    600

    700

    Lying/Sleep

    Sitting

    Standing

    Walking

    Personal

    necessities

    Moderate

    exercise

    Adolescents (13-17

    yrs)

    Adults (20-24 yrs)

    minute

    Ismail, 1998

    DAILY ACTIVITY PATTERN OF MALAYSIANS

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    DAILY ACTIVITY PATTERN OF MALAYSIANS

    ACCORDING TO AGE-GROUPS

    0

    10

    20

    30

    40

    50

    60

    70

    80

    90

    male

    female

    male

    female

    male

    female

    Adolescents

    Adults

    Elderly

    Light

    Moderate

    Active

    1

    2

    3

    Poh et al(1996),

    Ismail et al(1993)

    Razali & Ismail (1996)

    1

    2

    3

    %

    of d

    ay

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    Basal metabolic rate (MJ/day), total daily energy

    expenditure (MJ/day) and physical activity level (PAL)

    Subjects Age Male Female

    (yr) BMR TDEE PAL BMR TDEE PAL

    Adolescent25 12-14 5.08 7.89 1.55 4.80 7.09 1.48

    Adolescent26 16-18 5.76 8.64 1.50 5.02 7.64 1.52Young Adults27 18-30 5.85 9.40 1.61 4.77 7.58 1.59

    Adults27 30-60 5.66 9.53 1.68 4.79 8.17 1.70

    Elderly28 >60 4.92 7.35 1.50 4.37 6.74 1.54

    Armed Forces

    29

    20-30 5.74 12.08 2.10 NA NA NAElite Athlete30 20-30 6.84 14.91 2.18 5.39 10.67 1.98

    25 Yap (2001), 26 Victor (1999), 27 Ismail et al. (1994), 28 Razali (1996),29 Ismail et al. (1996), 30 Ismail et al. (1997)

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    Adapting exercise guidelines for energy balanceAdapting exercise guidelines for energy balance

    PAL 1.0

    PAL 1.8

    PAL 1.60

    PAL 1.50

    BMR

    CVD Guideline

    Sedentary

    Energy Balance

    Erlichman, Kerbey & James, 2002. Obesity

    Reviews, 3: 257-271 and 273-287.

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    How much physical activity is enough to preventunhealthy weight gain?

    Current guidelines of 30 minutes of moderate activity daily is

    important for limiting health risks to chronic diseases For preventing weight gain or regain, compelling evidence suggest

    a 60-90 minutes of moderate activity

    To prevent a transition to overweight and obesity, a PAL of 1.7 orapproximately 45-60 minutes per day of moderate activity isneeded.

    For children even more activity time is recommended

    Stock Conference, Bangkok, March 2002

    Issues

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    Diabetes

    Gall bladder disease

    Hypertension

    Dyslipidaemia

    Insulin resistance

    Breathlessness

    Sleep apnoea

    Greatly increased(relative risk >>3)

    Coronary heart disease

    Osteoarthritis (knees)

    Hyperuricaemia andgout

    Moderately increased(relative risk

    ca 2-3)

    Cancer (breast cancer in

    postmenopausal women,endometrial cancer, coloncancer

    Reproductive hormoneabnormalities

    Polycystic ovary syndrome

    Impaired fertilityLow back pain

    Increased anaesthetic risk

    Foetal defects arising frommaternal obesity

    Slightly increased(relative risk

    ca 1-2)

    Relative risk of health problems associated with

    obesity in developed countries .

    WHO, 1997

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    Social Consequences

    Community

    Loss of productivity

    Sick days

    Individual

    Employment prospects

    Marriage/DivorceStress/Self esteem

    Quality of Life

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    Annual direct costs of disease in relation to BMI

    Wolf and Colditz, 1996

    Ann

    ual

    co

    st ( U

    S$bi llion

    s)

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    Published Costs of Obesity

    Direct

    USA 1998

    $51.6 billion (5.7%)

    NZ 1996

    $135 million (2.5%)

    France 1995

    FF 12 billion (2%)

    Netherlands 1995

    DG 1 billion (4%)*

    Indirect

    $47.6 billion

    FF0.57 billion

    * 3% from BMI 25-30

    Caterson & Broom (2001)

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    Published Costs of Obesity

    Direct

    Canada 1999 (2.4%)

    $1.8 billion* UK 1994 (15%)

    GBP30 million

    England 1999 (1.1%)

    GBP130 million

    GBP15 million

    Indirect

    * BMI > 27

    GBP165 million

    Overweight

    Obese

    Caterson & Broom (2001)

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    Williamson DF et al, Am JWilliamson DF et al, Am J EpidemiolEpidemiol 19951995

    Lean MEJ et al, Diabetic Med 1990Lean MEJ et al, Diabetic Med 1990

    Benefits of 10 % weight lossBenefits of 10 % weight loss

    20% reduction20% reductionin all-causein all-causemortalitymortality

    30% reduction30% reductionin diabetes-in diabetes-associatedassociated

    mortalitymortality

    Life expectancy increases w ith w eight lossLife expectancy increases w ith w eight lossamong obese diabetic patientsamong obese diabetic patients

    Weight loss (kg) in first 12 monthsWeight loss (kg) in first 12 months

    Lean et al.Lean et al. DiabetDiabetMed, 1990; 7: 228Med, 1990; 7: 228--3333

    Life

    expectancy

    (yea

    rs)

    Life

    expectancy

    (yea

    rs) 1818

    1616

    1414

    1212

    1010

    88

    0000 22 44 66 88 1010 1212 1414 1616

    95% confidence interval95% confidence interval

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    A Vicious Circle

    Disrespect of

    obesity asa serious

    condition

    Overemphasis

    on cosmetic

    weight loss

    Advocatingabsurd body

    weight idealsProfessional

    Public

    Media

    Rossner, 1997

    CAUSAL WEB OF SOCIETAL INFLUENCES ON OBESITY PREVALENCE

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    INTERNATIONALFACTORS

    Development

    Globalizationof

    Markets

    SchoolFood

    WORK/SCHOOL/

    HOME

    Infections

    Labor

    WorksiteExercise

    SchoolActivity

    LeisureActivity/Facilities

    WorksiteFood

    Agriculture/Gardens/

    Local Markets

    COMMUNITIES

    Health CareSystem

    PublicSafety

    PublicTransport

    Manufactured/Imported

    Food

    Sanitation

    NATIONAL/STATE

    Food Policy

    Urbanization

    TransportPolicy

    EducationPolicy

    Health Policy

    OBESIT

    Y

    PREVALENCE

    INDIVIDUAL

    EnergyExpenditure

    FoodIntake:

    NutrientDensity

    Ritenbaugh C, Kumanyika S, Morabia A, Jeffery R, Antipatis V. IOTF website 1999: http://www.iotf.org

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    Strategy for thePrevention of

    Obesity- Malaysia

    G lNPANM II ( 2006-2015 )

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    Incorporating nutrition objectives and strategies into policies and

    programmes of relevant agencies

    Foundation

    strategy

    Facilitatingstrategies

    Improving household food security especially among the low income

    Promoting optimal infant & young children feeding practices

    Preventing and controlling nutritional deficiencies

    Promoting healthy eating and active living

    Supporting efforts to protect consumers in food quality & safety

    Specific objectivesTo improve

    nutritional

    status of all

    To preventand control

    diet-related

    non-communicable diseases

    TO ACHIEVE AND MAINTAIN THE NUTRITIONAL WELL-

    BEING OF MALAYSIANS

    General

    Objective

    Enablingstrategies

    Ensuring

    all have

    access tonutrition

    information

    Continuousassessment

    and monitoringof the nutrition

    Situation

    Promotingcontinuous

    researchanddevelopment

    Ensuringnutrition

    anddietetics arepractised

    by trainedprofessionals

    Strengthening

    institutionalcapacity innutritionalactivities

    NPANM II ( 2006 2015 )

    Specific objective 1

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    p j

    To Improve nutritional status

    The nutritional status of all Malaysians can be furtherenhanced through:

    Improving breastfeeding and complementary feedingpractices

    Improving food intake and dietary practices

    Reducing protein-energy malnutrition

    Reducing micronutrient deficiency

    Reducing overweight and obesity

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    Formation of Malaysian Council for ObesityPrevention (MCOP)

    Initiated 3 working groups namely:

    1) Childhood Obesity Prevention

    2) Increasing Awareness

    3) Research on Obesity Prevention

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    The current nutrition and health scenario suggests that

    Malaysia have not benefited from the western experience

    We need to intervene strategically before the typical

    dietary

    pattern associated with western affluence become

    widespread and established within our population

    The problem is real and need urgent attention for it may

    be just the tip of the ice-berg.

    There is a need to carry out National Nutrition Survey

    periodically

    There is a need for Health Economic Analysis

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    Slide 9

    http://c/My%20Documents/Bengkel%20IRPA%202003%20-%20metabolic%20cost.ppt#Slide%209http://c/My%20Documents/Bengkel%20IRPA%202003%20-%20metabolic%20cost.ppt#Slide%209