1. Dr Dipesh Tamrakar 1st Yrs JR SPH & CM

2. Content Introduction Problem Statement Important NTD in context to Nepal Impact Challenges Recent Advances 3. Introduction Neglected tropical disease is an umbrella term for alarge group of diseases. there is still ambiguity about the term neglected tropical diseases 4. Definition WHO...Chronically endemic and epidemic-prone tropical diseases, which have a very significant negative impact on the lives of poor populations [and] remain critically neglected in the global public health agenda. 5. Protozoan Infections Leishmaniasis Human African trypanosomiasis (sleeping sickness) Chagas disease Viral Infections Dengue & dengue haemorrhagic fever Rabies Bacterial Infections Leprosy Trachoma Buruli ulcer Endemic Trepanomatoses(Yaws, Pinta, Bejel Helminth Infections Soil-transmitted helminth infections (Ascariasis, Trichuriasis, Hookworm) Lymphatic filariasis (elephantiasis) Onchocerciasis (river blindness) Schistosomiasis Dracunculiasis (guineaworm disease) Cysticercosis and other zoonotic helminthiasis Food borne Nematodes(clonorchias is, opisthorchiasis, fasciolasis 6. Definition contd.. Global Network for Neglected Tropical Diseases The neglected tropical diseases are a group of 13 parasitic and bacterial infections that affect over 14 billion people, most of whom live on less than $125 per day. Diseases: Aascariasis, Buruliulcer, dracunculiasis, human Africantrypanosomiasis, hookworm, leishmaniasis, leprosy,lymphaticfilariasis, onchoceriasis, schistosomiasis, trachoma, trichuriasis 7. Defination contd Neglected Tropical Disease Program (USAID)These diseases disproportionately impact the poor and rural populations, who lack access to safe water, sanitation, and essential medicines. They cause sickness and disability, compromise childrens mental and physical development, and result in blindness and severe disfigurement. Targeted diseases: Lymphaticfilariasis, schistosomiasis, trachoma onchocerciasis, soiltransmitted helminthiasis 8. WHY They are called neglected Tropical Disease two important shared characteristics - First, these diseases predominate in the tropics - Second, they have all to a greater or lesser extent beenneglected by funders, researchers and policy-makers 9. Why neglected? Do not travel easily not a threat to Western society New tools and interventions not attractive-not asignificant market -