national engineering research center for biomaterials...
TRANSCRIPT
OUTLINE
The first national institute for biomaterials approved
by Ministry of Science & Technology in 2000, an
independent legal entity, relying on Sichuan
University
An innovation-platform of Sci. & Tech. for biomedical
engineering, set by Ministry of Education
The “International Sci. and Tech. cooperation and
exchange base for Biomedical Materials” in the
Ministry of Science and Technology.
Functions: research, education, industrial
incubator…
OUTLINE
NERCB
Chinese Committee for Biomaterials (CCBM)
Testing & Evaluation Center for Medical Devices &
Biomaterials (STEC-MDB)
R & D Department
Clinical
Application
Department
Business Dep.
& Information
Department
Dep. of
Middle Scale
Manufacturing
GMP scale
supporting organization established by
4
Staff & Students
Associate Prof.
Professor
Lecturer & Assistant R & D, Administration
Total staff: 120
Ph. D. Student
MS Student
Post Dr
458
65
58
25
1621
Total students: 118
All Professors have overseas background.
Current Research Projects
Provincial
National18
53
International
Provincial
Ongoing Projects (26)
Ministry of Science & Technology (MOST)
1 National Basic Research Program of China (973 Program)
3 National High Technology Research & Development
Programs (863 Program)
NSFC: 3 Key Research Programs
5 International Collaboration Programs
Products
HA Ceramic
Dental Implants
with HA Coating PLGA Barrier Film
PLA Adhesion-proof velum
HA powders Osteoinducing Ceramic
Artificial Hip Joint
with HA Coating
6 class III Products approved by CFDA
International Collaboration
Worldwide academic exchanges and
collaboration with key international institutes
on biomaterials have been established.
UK
Italy
Finland
Germany
The Netherlands
Sweden
USA
Australia
India
Japan
Korea
……
8
Honorary & Visiting Prof.
Honorary Professors
Prof. D. Williams, Liverpool University, UK
Prof. W. Bonfield , Cambridge University, UK
Prof. C. J. Kirkpatrick, Johannes Gutenberg University,
Germany, Chairman of ESB
Prof. K de Groot, University of Leiden, the Netherlands
Prof. JCY Leong, Academician of Chinese Academy of Science,
University of Hongkong
Prof. J. Kopecek, Univ. of Utah, USA
Prof. E. Wagner, University of Munich
Visiting Professors
U. Gross , Professor, Free University of Berlin, Germany
JCY Cheng, Professor, Chinese University of HK
PJ Li, Senior Material Scientist, DePuy Co.( Johnson &
Johnson), USA
Educations
9
An international committee for Ph. D dissertation defense
(China, Japan, Australia)
The Ph. D. candidate Co-supervised by XD Zhang &
Leiden Univ.
Graduate students
Co-advisors with famous oversea universities
Academic Collaboration
10
Zhang signed cooperationAgreement with J. Tanaka
Zhang, Bonfield, K.de GrootCooperation agreement onresearch & education
C.J. Kirkpatrick awardedthe Honorary Prof. of SCU
Gu signed cooperation Agreement with R. Brown in UCL
J. Kopecek (U Utah) awardedthe Honorary Prof. of SCU
RESEARCH AREA--1
Tissue Inducing Biomaterials
Bone inducing biomaterials
Calcium phosphate ceramics with a specific
composition and structure
Non-osseous tissue inducing biomaterials
Natural polymer composites for cartilage inducing
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RESEARCH AREA 2
Biomaterials for drug/gene delivery and
molecular imaging
Intelligent with sensitivities of temperature, pH or
bio-molecules
Targeting drug delivery systems of cellular-
specific
Novel Carriers
Polymeric micelles
Nanocapsules
Liposomes
Hydrogels
Hollow Nanoparticles
Peptide dendrimers12
RESEARCH AREA--3
Surface/Interface Modification
Bioactivation of Titanium surface Plasma Sprayed HA Coating
Liquid Phase Plasma Spray
Electrochemistry
Alkali-heat Treatment
Chlorine Group Immobilization (to inhibit bacterial growth)
Functionalization of Magnetic Nano-particles Interaction of functional groups with specific cells
Detection & separation of bio-molecules
Anti-thrombosis of Titanium Surface Plasma immersion ion implantation
Endothelium of surface
13
RESEARCH AREA--4
Novel Biomaterials: Molecular Design &
Controllable Preparation
Multifunctional peptide dendrimers Imaging probes
Drug delivery system
DNA vector for gene therapy
Biologic separation & detection
Supramolecular nano-hydrogel Drug delivery system
Tissue repair
Nano-biomaterals Composites of natural polymers and hydroxyapatite for
tissue regeneration, drug delivery and DNA vectors
Magnetic Nanoparticles for tissue repair, separation &
detection, targeting DDS, DNA vectors14
RESEARCH AREA--5
Biomaterials for Tissue EngineeringDesign & Synthesis of Novel Biodegradable
Polymers
Polyesters, Polycarbonate, Polypeptides and their
copolymers, Hydrogels, Natural Polymers
Bulk & Surface Modification of Biodegradable
Polymers
Fabrication of Tissue Engineering Scaffolds
Vascular Network
Cartilage
Bone
Cell-Scaffold Interactions
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Chinese Committee for Biomaterials (CCBM)
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Academic organization under the direction of the Chinese
Association for Sci. & Tech.
One of the six founders of International Union Society for
Biomaterials Science & Engineering (IUS-BSM)
Hosting & co-organizing international academic symposia
China-Europe Symposium on Biomaterials (once every two years)
Asian Symposium on Biomaterials (once every two years)
9th WBC (2012, Chengdu)
2014 National Nano-Biological and Medical conference
Testing & Evaluation Center for Medical Devices & Biomaterials (STEC-MDB)
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An independent national evaluation center, founded by
NERCB
Issuing test reports with legal authority in both China &
abroad
Service items
Class III & part of class II medical devices & biomaterials
Biocompatibility tests and evaluations according to ISO10993
Physical and chemical tests
Consulting services for product testing, standards set-up &
amendment, various training courses
Potential Collaboration
Scientific Collaboration To apply joint funding
To hold the Thematic Workshop
To build joint lab
Education Cooperation To supervise graduate students jointly and exchange
young scientists Short term: 1-3 months (Summer school etc.)
Long term: 1-3 years (Sandwich PhD etc.)
Industrial Cooperation To jointly establish biomaterials factories or provide
advanced manufacturing technique
Testing and Evaluation Center Support for research and product development
Results recognized by most organizations